μ Opiate receptor gene dose effects on different morphine actions: Evidence for differential in vivo μ receptor reserve

Neuropsychopharmacology

Volumn 25, Issue 1, 2001, Pages 41-54

  Sora, Ichiro ^a   Elmer, Greg ^b   Funada, Masahiko ^a,c   Pieper, Jeanne ^a   Li, Xiao Fei ^a   Hall, F Scott ^a   Uhl, George R ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

Author keywords

Conditioned place preference; Lethality; Locomotion; Physical dependence; Self administration; Tolerance; Transgenic knockout mice

Indexed keywords

MORPHINE SULFATE; MU OPIATE RECEPTOR; NALOXONE; RECEPTOR RESERVE;

ABSTINENCE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; ATTENUATION; CELL POPULATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DEPENDENCE; DRUG EFFECT; DRUG MECHANISM; DRUG SELF ADMINISTRATION; FEMALE; GENE DOSAGE; IN VIVO STUDY; LETHAL DOSE; LOCOMOTION; MALE; MOUSE; NONHUMAN; PAIN THRESHOLD; PLACE PREFERENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BRAIN CHEMISTRY; CONDITIONING (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LETHAL DOSE 50; MALE; MICE; MICE, KNOCKOUT; MORPHINE; MORPHINE DEPENDENCE; MOTOR ACTIVITY; NALOXONE; NARCOTIC ANTAGONISTS; NARCOTICS; NEURONS; NOCICEPTORS; PAIN MEASUREMENT; RECEPTORS, OPIOID, MU; REWARD; SELF ADMINISTRATION;

EID: 0035010041     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(00)00252-9     Document Type: Article

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