Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different ages

Journal of Neurochemistry

Volumn 78, Issue 2, 2001, Pages 339-348

  Maccarrone, Mauro ^a,b   Attinà, Marina ^a   Bari, Monica ^a   Cartoni, Antonella ^b   Ledent, Catherine ^a   Finazzi Agrò, Alessandro ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Anandamide hydrolase; Anandamide transporter; CB1 receptor knockout; CD1 mouse; Endocannabinoids

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ANANDAMIDE; CANNABINOID 1 RECEPTOR; FATTY ACID AMIDASE; PALMIDROL;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HIPPOCAMPUS; ISOELECTRIC POINT; MALE; MOLECULAR WEIGHT; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

ANIMALIA;

EID: 0034924282     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00413.x     Document Type: Article

References (41)

1. Modulation of neuronal serotonin uptake by the imipramine recognition site: Evidence for an endogenous ligand
2. 2 receptor responses by an anandamide transport inhibitor
3. Biosynthesis, uptake and degradation of anandamide and palmitoylethanolamide in leukocytes
4. Oleamide: An endogenous sleep-inducing lipid and prototypical member of a new class of biological signaling molecules
5. Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide
6. Oxidative metabolism of anandamide
7. Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain
8. Control of pain initiation by endogenous cannabinoids
9. 2 receptor mediated behaviour in the rat by oleamide and the role of cannabinoid receptors
10. Isolation and structure of a brain constituent that binds to the cannabinoid receptor
11. 2 receptor-mediated actions of anandamide in mouse brain
12. Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease
13. Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
14. Molecular characterization of human and mouse fatty acid amide hydrolase
15. Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity
16. Determination of the phospholipid precursor of anandamide and other N-acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons
17. Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain
18. Accumulation of N-arachidonoylethanolamide (anandamide) into cerebellar granule cells occurs via facilitated diffusion
19. Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter
20. Reversible hydrolysis and synthesis of anandamide demonstrated by recombinant rat fatty acid amide hydrolase
21. 1 receptor knockout mice
22. Anandamide hydrolysis by human cells in culture and brain
23. Anandamide uptake by human endothelial cells and its regulation by nitric oxide
24. Down-regulation of anandamide hydrolase in mouse uterus by sex hormones
25. Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors
26. Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage
27. GC/MS analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture
28. Putative role of neuronal 5-1ipoxygenase in an aging brain
29. Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): Vanilloid receptor ligands that inhibit anadamide-facilitated transport and bind to CB1 cannabinoid receptors
30. Pharmacology of cannabinoid CB1 and CB2 receptors
31. Structural determinants for recognition and translocation by the anandamide transporter
32. Cannabinoids, endogenous ligands and synthetic analogs
33. Rapid isoelectric focusing in a vertical polyacrylamide minigel system
34. Comparative biology of the endocannabinoid system. Possible role in the immune response
35. Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain
36. Anandamide: A candidate neurotransmitter heads for the big leagues
37. A second endogenous cannabinoid that modulates long-term potentiation
38. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
39. The effect of dioxygenation of N-linoleoylamides on their cannabinomimetic properties
40. Inhibition by anandamide of gap junctions and inercellular calcium signalling in striatal astrocytes
41. Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice