Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 12, 2009, Pages 4917-4922

  Pan, Ying Xian ^a   Xu, Jin ^a   Xu, Mingming ^a   Rossi, Grace C ^b   Matulonis, Joshua E ^a   Pasternak, Gavril W ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b LONG ISLAND UNIVERSITY   (United States)

Author keywords

Analgesia; Knockout; Opiate receptor

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; BETA FUNALTREXAMINE; DIAMORPHINE; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; FENTANYL; G PROTEIN COUPLED RECEPTOR; METHADONE; MORPHINE; MORPHINE 6 ACETATE; MORPHINE 6 GLUCURONIDE; MU 1 OPIATE RECEPTOR; MU OPIATE RECEPTOR; NALOXONE; NALTRINDOLE; UNCLASSIFIED DRUG; BETA-FUNALTREXAMINE; DRUG DERIVATIVE; NALTREXONE; OPRM PROTEIN, MOUSE;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG MEGADOSE; EXON; EXON 11; GASTROINTESTINAL TRANSIT; GENE DISRUPTION; GENETIC VARIABILITY; HOT PLATE TEST; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; TAIL FLICK TEST; THERMOREGULATION; ALTERNATIVE RNA SPLICING; ANIMAL; DRUG EFFECT; GENE TARGETING; GENETICS; HETEROZYGOTE; MOUSE MUTANT; MUTATION;

MUS; RATTUS;

ALTERNATIVE SPLICING; ANALGESIA; ANIMALS; EXONS; GASTROINTESTINAL TRANSIT; GENE TARGETING; HEROIN; HETEROZYGOTE; MICE; MICE, KNOCKOUT; MORPHINE; MUTATION; NALOXONE; NALTREXONE; RECEPTORS, OPIOID, MU;

EID: 63849228557     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0811586106     Document Type: Article

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