-
1
-
-
84859483480
-
Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures
-
Abraham J., Fox P.D., Condello C., Bartolini A., Koh S. Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures. Neurobiol. Dis. 2012, 46:425-430.
-
(2012)
Neurobiol. Dis.
, vol.46
, pp. 425-430
-
-
Abraham, J.1
Fox, P.D.2
Condello, C.3
Bartolini, A.4
Koh, S.5
-
2
-
-
84891534084
-
Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression
-
Amada N., Yamasaki Y., Williams C.M., Whalley B.J. Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression. Peer J. 2013, 1:e214.
-
(2013)
Peer J.
, vol.1
-
-
Amada, N.1
Yamasaki, Y.2
Williams, C.M.3
Whalley, B.J.4
-
3
-
-
0023041272
-
Anticonvulsant effects of cannabidiol
-
(Letter)
-
Ames F.R., Cridland S. Anticonvulsant effects of cannabidiol. S. Afr. Med. J. 1986, 69:14. (Letter).
-
(1986)
S. Afr. Med. J.
, vol.69
, pp. 14
-
-
Ames, F.R.1
Cridland, S.2
-
4
-
-
84888202438
-
Glial adenosine kinase - a neuropathological marker of the epileptic brain
-
Aronica E., Sandau U.S., Iyer A., Boison D. Glial adenosine kinase - a neuropathological marker of the epileptic brain. Neurochem. Int. 2013, 63:688-695.
-
(2013)
Neurochem. Int.
, vol.63
, pp. 688-695
-
-
Aronica, E.1
Sandau, U.S.2
Iyer, A.3
Boison, D.4
-
5
-
-
33846837628
-
Serotonin and epilepsy
-
Bagdy G., Kecskemeti V., Riba P., Jakus R. Serotonin and epilepsy. J. Neurochem. 2007, 100:857-873.
-
(2007)
J. Neurochem.
, vol.100
, pp. 857-873
-
-
Bagdy, G.1
Kecskemeti, V.2
Riba, P.3
Jakus, R.4
-
6
-
-
33744456750
-
Pharmacokinetic and behavioral effects of allopregnanolone in healthy women
-
Balgård M., Nyberg S., Spigset O., Andersson A., Porankiewicz-Asplund J., Purdy R.H., Zhu D., Bäckström T., Poromaa I.S. Pharmacokinetic and behavioral effects of allopregnanolone in healthy women. Psychopharmacology (Berl.) 2006, 186:414-424.
-
(2006)
Psychopharmacology (Berl.)
, vol.186
, pp. 414-424
-
-
Balgård, M.1
Nyberg, S.2
Spigset, O.3
Andersson, A.4
Porankiewicz-Asplund, J.5
Purdy, R.H.6
Zhu, D.7
Bäckström, T.8
Poromaa, I.S.9
-
7
-
-
84883487503
-
The effect of minocycline on seizures induced by amygdala kindling in rats
-
Beheshti Nasr S.M., Moghimi A., Mohammad-Zadeh M., Shamsizadeh A., Noorbakhsh S.M. The effect of minocycline on seizures induced by amygdala kindling in rats. Seizure 2013, 22:670-674.
-
(2013)
Seizure
, vol.22
, pp. 670-674
-
-
Beheshti Nasr, S.M.1
Moghimi, A.2
Mohammad-Zadeh, M.3
Shamsizadeh, A.4
Noorbakhsh, S.M.5
-
8
-
-
0024321145
-
Anticonvulsant profile of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one
-
Belelli D., Bolger M.B., Gee K.W. Anticonvulsant profile of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one. Eur. J. Pharmacol. 1989, 166:325-329.
-
(1989)
Eur. J. Pharmacol.
, vol.166
, pp. 325-329
-
-
Belelli, D.1
Bolger, M.B.2
Gee, K.W.3
-
11
-
-
84866681617
-
The GABA excitatory/inhibitory shift in brain maturation and neurological disorders
-
Ben-Ari Y., Khalilov I., Kahle K.T., Cherubini E. The GABA excitatory/inhibitory shift in brain maturation and neurological disorders. Neuroscientist 2012, 18:467-486.
-
(2012)
Neuroscientist
, vol.18
, pp. 467-486
-
-
Ben-Ari, Y.1
Khalilov, I.2
Kahle, K.T.3
Cherubini, E.4
-
12
-
-
77954852980
-
Valnoctamide as valproate substitute with low teratogenic potential in mania: double blind controlled clinical trial
-
Bersudsky Y., Applebaum Y., Sharony A., Mishory A., Poderbeasky A., Agam G., Belmaker R.H. Valnoctamide as valproate substitute with low teratogenic potential in mania: double blind controlled clinical trial. Bipolar Disord. 2010, 12:376-382.
-
(2010)
Bipolar Disord.
, vol.12
, pp. 376-382
-
-
Bersudsky, Y.1
Applebaum, Y.2
Sharony, A.3
Mishory, A.4
Poderbeasky, A.5
Agam, G.6
Belmaker, R.H.7
-
13
-
-
84862858037
-
Chemical properties of antiepileptic drugs (AEDs)
-
Bialer M. Chemical properties of antiepileptic drugs (AEDs). Adv. Drug Deliv. Rev. 2012, 64:887-895.
-
(2012)
Adv. Drug Deliv. Rev.
, vol.64
, pp. 887-895
-
-
Bialer, M.1
-
14
-
-
78650178478
-
Progress report on new antiepileptic drugs: a summary of the Tenth Eilat Conference (EILAT X)
-
Bialer M., Johannessen S.I., Levy R.H., Perucca E., Tomson T., White H.S. Progress report on new antiepileptic drugs: a summary of the Tenth Eilat Conference (EILAT X). Epilepsy Res. 2010, 92:89-124.
-
(2010)
Epilepsy Res.
, vol.92
, pp. 89-124
-
-
Bialer, M.1
Johannessen, S.I.2
Levy, R.H.3
Perucca, E.4
Tomson, T.5
White, H.S.6
-
15
-
-
0033061573
-
Progress report on new antiepileptic drugs: a summary of the fourth Eilat conference (EILAT IV)
-
Bialer M., Johannessen S.I., Kupferberg H.J., Levy R.H., Loiseau P., Perucca E. Progress report on new antiepileptic drugs: a summary of the fourth Eilat conference (EILAT IV). Epilepsy Res. 1999, 34:1-41.
-
(1999)
Epilepsy Res.
, vol.34
, pp. 1-41
-
-
Bialer, M.1
Johannessen, S.I.2
Kupferberg, H.J.3
Levy, R.H.4
Loiseau, P.5
Perucca, E.6
-
16
-
-
0035200133
-
Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V)
-
Bialer M., Johannessen S.I., Kupferberg H.J., Levy R.H., Loiseau P., Perucca E. Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V). Epilepsy Res. 2001, 43:11-58.
-
(2001)
Epilepsy Res.
, vol.43
, pp. 11-58
-
-
Bialer, M.1
Johannessen, S.I.2
Kupferberg, H.J.3
Levy, R.H.4
Loiseau, P.5
Perucca, E.6
-
17
-
-
84872163082
-
Progress report on new antiepileptic drugs: a summary of the Eleventh Eilat Conference (EILAT XI)
-
Bialer M., Johannessen S.I., Levy R.H., Perucca E., Tomson T., White H.S. Progress report on new antiepileptic drugs: a summary of the Eleventh Eilat Conference (EILAT XI). Epilepsy Res. 2013, 103:2-30.
-
(2013)
Epilepsy Res.
, vol.103
, pp. 2-30
-
-
Bialer, M.1
Johannessen, S.I.2
Levy, R.H.3
Perucca, E.4
Tomson, T.5
White, H.S.6
-
18
-
-
57849141134
-
Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX)
-
Bialer M., Johannessen S.I., Levy R.H., Perucca E., Tomson T., White H.S. Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009, 83:1-43.
-
(2009)
Epilepsy Res.
, vol.83
, pp. 1-43
-
-
Bialer, M.1
Johannessen, S.I.2
Levy, R.H.3
Perucca, E.4
Tomson, T.5
White, H.S.6
-
19
-
-
74049163222
-
Key factors in the discovery and development of new antiepileptic drugs (AEDs)
-
Bialer M., White H.S. Key factors in the discovery and development of new antiepileptic drugs (AEDs). Nat. Rev. Drug Discov. 2010, 9:68-83.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 68-83
-
-
Bialer, M.1
White, H.S.2
-
20
-
-
33846228427
-
Valproic acid - second generation
-
Bialer M., Yagen B. Valproic acid - second generation. Neurotherapeutics 2007, 4:130-137.
-
(2007)
Neurotherapeutics
, vol.4
, pp. 130-137
-
-
Bialer, M.1
Yagen, B.2
-
21
-
-
10744229235
-
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain
-
Bisogno T., Howell F., Williams G., Minassi A., Cascio M.G., Ligresti A., Matias I., Schiano-Moriello A., Paul P., Williams E.J., Gangadharan U., Hobbs C., Di Marzo V., Doherty P. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J. Cell Biol. 2003, 163:463-468.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 463-468
-
-
Bisogno, T.1
Howell, F.2
Williams, G.3
Minassi, A.4
Cascio, M.G.5
Ligresti, A.6
Matias, I.7
Schiano-Moriello, A.8
Paul, P.9
Williams, E.J.10
Gangadharan, U.11
Hobbs, C.12
Di Marzo, V.13
Doherty, P.14
-
22
-
-
84892937581
-
Brivaracetam as adjunctive treatment for uncontrolled partial epilepsy in adults: a phase III randomized, double-blind, placebo-controlled trial
-
Biton V., Berkovic S.F., Abou-Khalil B., Sperling M.R., Johnson M.E., Lu S. Brivaracetam as adjunctive treatment for uncontrolled partial epilepsy in adults: a phase III randomized, double-blind, placebo-controlled trial. Epilepsia 2014, 55:57-66.
-
(2014)
Epilepsia
, vol.55
, pp. 57-66
-
-
Biton, V.1
Berkovic, S.F.2
Abou-Khalil, B.3
Sperling, M.R.4
Johnson, M.E.5
Lu, S.6
-
24
-
-
84870288653
-
Adenosine augmentation therapy for epilepsy
-
Oxford University Press, Oxford, J.L. Noebels, M. Avoli, M.A. Rogawski, R.W. Olsen, A.V. Delgado-Escueta (Eds.)
-
Boison D. Adenosine augmentation therapy for epilepsy. Jasper's Basic Mechanisms of the Epilepsies 2012, 1150-1160. Oxford University Press, Oxford. J.L. Noebels, M. Avoli, M.A. Rogawski, R.W. Olsen, A.V. Delgado-Escueta (Eds.).
-
(2012)
Jasper's Basic Mechanisms of the Epilepsies
, pp. 1150-1160
-
-
Boison, D.1
-
25
-
-
41149145189
-
Adenosine as a modulator of brain activity
-
Boison D. Adenosine as a modulator of brain activity. Drug News Perspect. 2007, 20:607-611.
-
(2007)
Drug News Perspect.
, vol.20
, pp. 607-611
-
-
Boison, D.1
-
26
-
-
84876373418
-
Adenosine kinase: exploitation for therapeutic gain
-
Boison D. Adenosine kinase: exploitation for therapeutic gain. Pharmacol. Rev. 2013, 65:906-943.
-
(2013)
Pharmacol. Rev.
, vol.65
, pp. 906-943
-
-
Boison, D.1
-
27
-
-
84924294771
-
Subchronic (45 day) oral toxicity study of 2-deoxy-d-glucose (2-DG) in F344 rats with a 15 day recovery period
-
Bordelon N.R., Koester A.J., Arndt T.P., Hong S.P., Brys A.M., Sutula T.P., Joshi P.S., Terse P.S. Subchronic (45 day) oral toxicity study of 2-deoxy-d-glucose (2-DG) in F344 rats with a 15 day recovery period. Int. J. Toxicol. 2013, 33:66.
-
(2013)
Int. J. Toxicol.
, vol.33
, pp. 66
-
-
Bordelon, N.R.1
Koester, A.J.2
Arndt, T.P.3
Hong, S.P.4
Brys, A.M.5
Sutula, T.P.6
Joshi, P.S.7
Terse, P.S.8
-
28
-
-
42549172614
-
Safety and tolerability of brivaracetam (ucb 34714) as adjunctive treatment in adults with refractory partial-onset seizures
-
Brodsky A., Costantini C., von Rosenstiel P. Safety and tolerability of brivaracetam (ucb 34714) as adjunctive treatment in adults with refractory partial-onset seizures. Epilepsia 2007, 48(Suppl. 6):342.
-
(2007)
Epilepsia
, vol.48
, pp. 342
-
-
Brodsky, A.1
Costantini, C.2
von Rosenstiel, P.3
-
29
-
-
84913596032
-
Pediatric super-refractory status epilepticus treated with allopregnanolone
-
Broomall E., Natale J.E., Grimason M., Goldstein J., Smith C.M., Chang C., Kanes S., Rogawski M.A., Wainwright M.S. Pediatric super-refractory status epilepticus treated with allopregnanolone. Ann. Neurol. 2014, 76:911-915.
-
(2014)
Ann. Neurol.
, vol.76
, pp. 911-915
-
-
Broomall, E.1
Natale, J.E.2
Grimason, M.3
Goldstein, J.4
Smith, C.M.5
Chang, C.6
Kanes, S.7
Rogawski, M.A.8
Wainwright, M.S.9
-
30
-
-
0019604414
-
Hypnotic and antiepileptic effects of cannabidiol
-
Carlini E.A., Cunha J.M. Hypnotic and antiepileptic effects of cannabidiol. J. Clin. Pharmacol. 1981, 21:417S-427S.
-
(1981)
J. Clin. Pharmacol.
, vol.21
, pp. 417S-427S
-
-
Carlini, E.A.1
Cunha, J.M.2
-
31
-
-
14444270606
-
A receptor
-
A receptor. J. Pharmacol. Exp. Ther. 1997, 280:1284-1295.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.280
, pp. 1284-1295
-
-
Carter, R.B.1
Wood, P.L.2
Wieland, S.3
Hawkinson, J.E.4
Belelli, D.5
Lambert, J.J.6
White, H.S.7
Wolf, H.H.8
Mirsadeghi, S.9
Tahir, S.H.10
Bolger, M.B.11
Lan, N.C.12
Gee, K.W.13
-
32
-
-
84860146607
-
Results of a phase II placebo-controlled randomized trial of minocycline in acute spinal cord injury
-
Casha S., Zygun D., McGowan M.D., Bains I., Yong V.W., Hurlbert R.J. Results of a phase II placebo-controlled randomized trial of minocycline in acute spinal cord injury. Brain 2012, 135:1224-1236.
-
(2012)
Brain
, vol.135
, pp. 1224-1236
-
-
Casha, S.1
Zygun, D.2
McGowan, M.D.3
Bains, I.4
Yong, V.W.5
Hurlbert, R.J.6
-
33
-
-
84924324220
-
Subtle seizures after TBI in a unique strain of kindling-susceptible rats: electrographic, behavioral, and phenotypic features
-
Cech C., Hanson M., Ting L., Mulvey B., Langberg T., Hutchinson E., Rutecki P., Sutula T.P. Subtle seizures after TBI in a unique strain of kindling-susceptible rats: electrographic, behavioral, and phenotypic features. Poster 1.027 American Epilepsy Society 2012, http://www.aesnet.org/.
-
(2012)
Poster 1.027 American Epilepsy Society
-
-
Cech, C.1
Hanson, M.2
Ting, L.3
Mulvey, B.4
Langberg, T.5
Hutchinson, E.6
Rutecki, P.7
Sutula, T.P.8
-
35
-
-
33745315699
-
Reported medication use in the neonatal intensive care unit: data from a large national data set
-
Clark R.H., Bloom B.T., Spitzer A.R., Gerstmann D.R. Reported medication use in the neonatal intensive care unit: data from a large national data set. Pediatrics 2006, 117:1979-1987.
-
(2006)
Pediatrics
, vol.117
, pp. 1979-1987
-
-
Clark, R.H.1
Bloom, B.T.2
Spitzer, A.R.3
Gerstmann, D.R.4
-
36
-
-
0029780405
-
35S]-TBPS binding in the brain of rats exposed to isoniazid, pentylenetetrazol or stress
-
35S]-TBPS binding in the brain of rats exposed to isoniazid, pentylenetetrazol or stress. Br. J. Pharmcol. 1996, 118:839-846.
-
(1996)
Br. J. Pharmcol.
, vol.118
, pp. 839-846
-
-
Concas, A.1
Mostallino, M.C.2
Perra, C.3
Lener, R.4
Roscetti, G.5
Barbaccia, M.L.6
Purdy, R.H.7
Biggio, G.8
-
37
-
-
33644872086
-
Privileged structures as leads in medicinal chemistry
-
Costantino L., Barlocco D. Privileged structures as leads in medicinal chemistry. Curr. Med. Chem. 2006, 13:65-85.
-
(2006)
Curr. Med. Chem.
, vol.13
, pp. 65-85
-
-
Costantino, L.1
Barlocco, D.2
-
38
-
-
84879070549
-
MTOR inhibitors as a new therapeutic option for epilepsy
-
Curatolo P., Moavero R. mTOR inhibitors as a new therapeutic option for epilepsy. Expert Rev. Neurother. 2013, 13:627-638.
-
(2013)
Expert Rev. Neurother.
, vol.13
, pp. 627-638
-
-
Curatolo, P.1
Moavero, R.2
-
39
-
-
84874849789
-
MTOR inhibitors in tuberous sclerosis complex
-
Curatolo P., Moavero R. mTOR inhibitors in tuberous sclerosis complex. Curr. Neuropharmacol. 2012, 10:404-415.
-
(2012)
Curr. Neuropharmacol.
, vol.10
, pp. 404-415
-
-
Curatolo, P.1
Moavero, R.2
-
40
-
-
17144373720
-
Inhibitors of the mammalian target of rapamycin
-
Dancey J.E. Inhibitors of the mammalian target of rapamycin. Expert Opin. Investig. Drugs 2005, 14:313-328.
-
(2005)
Expert Opin. Investig. Drugs
, vol.14
, pp. 313-328
-
-
Dancey, J.E.1
-
41
-
-
79960328574
-
Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes
-
De Petrocellis L., Ligresti A., Moriello A.S., Allara M., Bisogno T., Petrosino S., Stott C.G., Di Marzo V. Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. Br. J. Pharmacol. 2011, 163:1479-1494.
-
(2011)
Br. J. Pharmacol.
, vol.163
, pp. 1479-1494
-
-
De Petrocellis, L.1
Ligresti, A.2
Moriello, A.S.3
Allara, M.4
Bisogno, T.5
Petrosino, S.6
Stott, C.G.7
Di Marzo, V.8
-
42
-
-
84855345743
-
Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation
-
De Petrocellis L., Orlando P., Moriello A.S., Aviello G., Stott C., Izzo A.A., Di Marzo V. Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. Acta Physiol. (Oxford) 2012, 294:255-266.
-
(2012)
Acta Physiol. (Oxford)
, vol.294
, pp. 255-266
-
-
De Petrocellis, L.1
Orlando, P.2
Moriello, A.S.3
Aviello, G.4
Stott, C.5
Izzo, A.A.6
Di Marzo, V.7
-
43
-
-
84856628201
-
Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Delta(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour
-
Deiana S., Watanabe A., Yamasaki Y., Amada N., Arthur M., Fleming S., Woodcock H., Dorward P., Pigliacampo B., Close S., Platt B., Riedel G. Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Delta(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour. Psychopharmacology (Berl) 2012, 219:859-873.
-
(2012)
Psychopharmacology (Berl)
, vol.219
, pp. 859-873
-
-
Deiana, S.1
Watanabe, A.2
Yamasaki, Y.3
Amada, N.4
Arthur, M.5
Fleming, S.6
Woodcock, H.7
Dorward, P.8
Pigliacampo, B.9
Close, S.10
Platt, B.11
Riedel, G.12
-
44
-
-
4243159924
-
Privileged structures: applications in drug discovery
-
DeSimone R.W., Currie K.S., Mitchell S.A., Darrow J.W., Pippin D.A. Privileged structures: applications in drug discovery. Comb. Chem. High Throughput Screen. 2004, 7:473-494.
-
(2004)
Comb. Chem. High Throughput Screen.
, vol.7
, pp. 473-494
-
-
DeSimone, R.W.1
Currie, K.S.2
Mitchell, S.A.3
Darrow, J.W.4
Pippin, D.A.5
-
45
-
-
77956010986
-
Brivaracetam does not alter spatial learning and memory in both normal and amygdala-kindled rats
-
Detrait E.R., Leclercq K., Loscher W., Potschka H., Niespodziany I., Hanon E., Kaminski R.M., Matagne A., Lamberty Y. Brivaracetam does not alter spatial learning and memory in both normal and amygdala-kindled rats. Epilepsy Res. 2010, 91:74-83.
-
(2010)
Epilepsy Res.
, vol.91
, pp. 74-83
-
-
Detrait, E.R.1
Leclercq, K.2
Loscher, W.3
Potschka, H.4
Niespodziany, I.5
Hanon, E.6
Kaminski, R.M.7
Matagne, A.8
Lamberty, Y.9
-
46
-
-
84902304606
-
Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
-
Devinsky O., Cilio R., Cross H., Fernandez-Ruiz J., French J., Hill C., Katz R., Di Marzo V., Jutras-Aswad D., Notcutt W.G., Martinez-Orgado J., Robson P.J., Rohrback B.G., Thiele E., Whalley B., Friedman D. Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders. Epilepsia 2014, 55:791-802.
-
(2014)
Epilepsia
, vol.55
, pp. 791-802
-
-
Devinsky, O.1
Cilio, R.2
Cross, H.3
Fernandez-Ruiz, J.4
French, J.5
Hill, C.6
Katz, R.7
Di Marzo, V.8
Jutras-Aswad, D.9
Notcutt, W.G.10
Martinez-Orgado, J.11
Robson, P.J.12
Rohrback, B.G.13
Thiele, E.14
Whalley, B.15
Friedman, D.16
-
47
-
-
34848912806
-
Serotonin-1A receptor imaging in recurrent depression: replication and literature review
-
Drevets W.C., Thase M.E., Moses-Kolko E.L., Price J., Frank E., Kupfer D.J., Mathis C. Serotonin-1A receptor imaging in recurrent depression: replication and literature review. Nucl. Med. Biol. 2007, 34:865-877.
-
(2007)
Nucl. Med. Biol.
, vol.34
, pp. 865-877
-
-
Drevets, W.C.1
Thase, M.E.2
Moses-Kolko, E.L.3
Price, J.4
Frank, E.5
Kupfer, D.J.6
Mathis, C.7
-
48
-
-
0034746911
-
Identification of rat H3 receptor isoforms with different brain expression and signalling properties
-
Drutel G., Peitsaro N., Karlstedt K., Wieland K., Smit M.J., Timmerman H., Panula P., Leurs R. Identification of rat H3 receptor isoforms with different brain expression and signalling properties. Mol. Pharmacol. 2001, 59:1-8.
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 1-8
-
-
Drutel, G.1
Peitsaro, N.2
Karlstedt, K.3
Wieland, K.4
Smit, M.J.5
Timmerman, H.6
Panula, P.7
Leurs, R.8
-
49
-
-
36749018204
-
Privileged structures: a useful concept for the rational design of new lead drug candidates
-
Duarte C.D., Barreiro E.J., Fraga C.A. Privileged structures: a useful concept for the rational design of new lead drug candidates. Mini Rev. Med. Chem. 2007, 7:1108-1119.
-
(2007)
Mini Rev. Med. Chem.
, vol.7
, pp. 1108-1119
-
-
Duarte, C.D.1
Barreiro, E.J.2
Fraga, C.A.3
-
50
-
-
30744467689
-
NKCC1 transporter facilitates seizures in the developing brain
-
Dzhala V.I., Talos D.M., Sdrulla D.A., Brumback A.C., Mathews G.C., Benke T.A., Delpire E., Jensen F.E., Staley K.J. NKCC1 transporter facilitates seizures in the developing brain. Nat. Med. 2005, 11:1205-1213.
-
(2005)
Nat. Med.
, vol.11
, pp. 1205-1213
-
-
Dzhala, V.I.1
Talos, D.M.2
Sdrulla, D.A.3
Brumback, A.C.4
Mathews, G.C.5
Benke, T.A.6
Delpire, E.7
Jensen, F.E.8
Staley, K.J.9
-
51
-
-
84872070832
-
Bumetanide reduces seizure frequency in patients with temporal lobe epilepsy
-
Eftekhari S., Mehvari Habibabadi J., Najafi Ziarani M., Hashemi Fesharaki S.S., Gharakhani M., Mostafavi H., Joghataei M.T., Beladimoghadam N., Rahimian E., Hadjighassem M.R. Bumetanide reduces seizure frequency in patients with temporal lobe epilepsy. Epilepsia 2013, 54:9-12.
-
(2013)
Epilepsia
, vol.54
, pp. 9-12
-
-
Eftekhari, S.1
Mehvari Habibabadi, J.2
Najafi Ziarani, M.3
Hashemi Fesharaki, S.S.4
Gharakhani, M.5
Mostafavi, H.6
Joghataei, M.T.7
Beladimoghadam, N.8
Rahimian, E.9
Hadjighassem, M.R.10
-
52
-
-
84897438188
-
The other side of the histamine H3 receptor
-
Ellenbroek B.A., Ghiabi B. The other side of the histamine H3 receptor. Trends Neurosci. 2014, 37:191-199.
-
(2014)
Trends Neurosci.
, vol.37
, pp. 191-199
-
-
Ellenbroek, B.A.1
Ghiabi, B.2
-
53
-
-
0033537263
-
The effects of pharmacological doses of 2-deoxyglucose on cerebral blood flow in healthy volunteers
-
Elman I., Sokoloff L., Adler C.M., Weisenfeld N., Brier A. The effects of pharmacological doses of 2-deoxyglucose on cerebral blood flow in healthy volunteers. Brain Res. 1999, 815:243-249.
-
(1999)
Brain Res.
, vol.815
, pp. 243-249
-
-
Elman, I.1
Sokoloff, L.2
Adler, C.M.3
Weisenfeld, N.4
Brier, A.5
-
54
-
-
0029431596
-
Anticonvulsant effect of fluoxetine in humans
-
Favale E., Rubino V., Mainardi P., Lunardi G., Albano C. Anticonvulsant effect of fluoxetine in humans. Neurology 1995, 45:1926-1927.
-
(1995)
Neurology
, vol.45
, pp. 1926-1927
-
-
Favale, E.1
Rubino, V.2
Mainardi, P.3
Lunardi, G.4
Albano, C.5
-
55
-
-
77955452826
-
Adjunctive brivaracetam for refractory partial-onset seizures. A randomized, controlled trial
-
French J.A., Costantini C., Brodsky A., von Rosenstiel P. Adjunctive brivaracetam for refractory partial-onset seizures. A randomized, controlled trial. Neurology 2010, 75:519-525.
-
(2010)
Neurology
, vol.75
, pp. 519-525
-
-
French, J.A.1
Costantini, C.2
Brodsky, A.3
von Rosenstiel, P.4
-
57
-
-
33750443292
-
2-Deoxy-d-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure
-
Garriga-Canut M., Schoenike B., Qazi R., Bergendahl K., Daley T.J., Pfender R., Morrison J.F., Ockuly J., Stafstrom C., Sutula T., Roopra A. 2-Deoxy-d-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure. Nat. Neurosci. 2006, 9:1382-1387.
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 1382-1387
-
-
Garriga-Canut, M.1
Schoenike, B.2
Qazi, R.3
Bergendahl, K.4
Daley, T.J.5
Pfender, R.6
Morrison, J.F.7
Ockuly, J.8
Stafstrom, C.9
Sutula, T.10
Roopra, A.11
-
58
-
-
77955340185
-
Anticonvulsant and proconvulsant actions of 2-deoxy-d-glucose
-
Gasior M., Yankura J., Hartman A.L., French A., Rogawski M. Anticonvulsant and proconvulsant actions of 2-deoxy-d-glucose. Epilepsia 2010, 51:1385-1394.
-
(2010)
Epilepsia
, vol.51
, pp. 1385-1394
-
-
Gasior, M.1
Yankura, J.2
Hartman, A.L.3
French, A.4
Rogawski, M.5
-
59
-
-
84962482426
-
Whole cannabis extract of high concentration cannabidiol may calm seizures in highly refractory pediatric epilepsies
-
Gedde A.A., Maa E. Whole cannabis extract of high concentration cannabidiol may calm seizures in highly refractory pediatric epilepsies. American Epilepsy Society Annual Meeting, 3.330 2013.
-
(2013)
American Epilepsy Society Annual Meeting, 3.330
-
-
Gedde, A.A.1
Maa, E.2
-
60
-
-
67349158641
-
The histamine H3 receptor as a therapeutic drug target for CNS disorders
-
Gemkow M.J., Davenport A.J., Harich S., Ellenbroek B.A., Cesura A., Hallett D. The histamine H3 receptor as a therapeutic drug target for CNS disorders. Drug Discov. Today 2009, 14:509-515.
-
(2009)
Drug Discov. Today
, vol.14
, pp. 509-515
-
-
Gemkow, M.J.1
Davenport, A.J.2
Harich, S.3
Ellenbroek, B.A.4
Cesura, A.5
Hallett, D.6
-
61
-
-
79957889858
-
Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: relationship to anti-convulsant properties
-
Gillard M., Fuks B., Leclercq K., Matagne A. Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: relationship to anti-convulsant properties. Eur. J. Pharmacol. 2011, 664:36-44.
-
(2011)
Eur. J. Pharmacol.
, vol.664
, pp. 36-44
-
-
Gillard, M.1
Fuks, B.2
Leclercq, K.3
Matagne, A.4
-
63
-
-
36148960127
-
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial
-
Gordon P.H., Moore D.H., Miller R.G., Florence J.M., Verheijde J.L., Doorish C., Hilton J.F., Spitalny G.M., MacArthur R.B., Mitsumoto H., Neville H.E., Boylan K., Mozaffar T., Belsh J.M., Ravits J., Bedlack R.S., Graves M.C., McCluskey L.F., Barohn R.J., Tandan R. Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial. Lancet Neurol. 2007, 6:1045-1053.
-
(2007)
Lancet Neurol.
, vol.6
, pp. 1045-1053
-
-
Gordon, P.H.1
Moore, D.H.2
Miller, R.G.3
Florence, J.M.4
Verheijde, J.L.5
Doorish, C.6
Hilton, J.F.7
Spitalny, G.M.8
MacArthur, R.B.9
Mitsumoto, H.10
Neville, H.E.11
Boylan, K.12
Mozaffar, T.13
Belsh, J.M.14
Ravits, J.15
Bedlack, R.S.16
Graves, M.C.17
McCluskey, L.F.18
Barohn, R.J.19
Tandan, R.20
more..
-
65
-
-
85006171542
-
Marijuana: current concepts
-
Greydanus D.E., Hawver E.K., Greydanus M.M., Merrick J. Marijuana: current concepts. Front. Public Health 2013, 1:42.
-
(2013)
Front. Public Health
, vol.1
, pp. 42
-
-
Greydanus, D.E.1
Hawver, E.K.2
Greydanus, M.M.3
Merrick, J.4
-
67
-
-
0014232652
-
Steroids. CCCX. Structure-activity relationship of some steroidal hypnotic agents
-
Gyermek L., Iriarte J., Crabbé P. Steroids. CCCX. Structure-activity relationship of some steroidal hypnotic agents. J. Med. Chem. 1968, 11:117-125.
-
(1968)
J. Med. Chem.
, vol.11
, pp. 117-125
-
-
Gyermek, L.1
Iriarte, J.2
Crabbé, P.3
-
68
-
-
0021040264
-
Bumetanide: a new loop diuretic (Bumex, Roche Laboratories)
-
Halstenson C.E., Matzke G.R. Bumetanide: a new loop diuretic (Bumex, Roche Laboratories). Drug Intell. Clin. Pharm. 1983, 17:786-797.
-
(1983)
Drug Intell. Clin. Pharm.
, vol.17
, pp. 786-797
-
-
Halstenson, C.E.1
Matzke, G.R.2
-
69
-
-
35848942392
-
5-HT1A receptor binding in temporal lobe epilepsy patients with and without major depression
-
Hasler G., Bonwetsch R., Giovacchini G., Toczek M.T., Bagic A., Luckenbaugh D.A., Drevets W.C., Theodore W.H. 5-HT1A receptor binding in temporal lobe epilepsy patients with and without major depression. Biol. Psychiatry 2007, 62:1258-1264.
-
(2007)
Biol. Psychiatry
, vol.62
, pp. 1258-1264
-
-
Hasler, G.1
Bonwetsch, R.2
Giovacchini, G.3
Toczek, M.T.4
Bagic, A.5
Luckenbaugh, D.A.6
Drevets, W.C.7
Theodore, W.H.8
-
70
-
-
84883200078
-
Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus
-
Hen N., Shekh-Ahmad T., Yagen B., McDonough J.H., Finnell R.H., Wlodarczyk B., Bialer M. Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus. J. Med. Chem. 2013, 56:6467-6477.
-
(2013)
J. Med. Chem.
, vol.56
, pp. 6467-6477
-
-
Hen, N.1
Shekh-Ahmad, T.2
Yagen, B.3
McDonough, J.H.4
Finnell, R.H.5
Wlodarczyk, B.6
Bialer, M.7
-
71
-
-
33646382411
-
Minocycline inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in mice
-
Heo K., Cho Y.J., Cho K.J., Kim H.W., Kim H.J., Shin H.Y., Lee B.I., Kim G.W. Minocycline inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in mice. Neurosci. Lett. 2006, 398:195-200.
-
(2006)
Neurosci. Lett.
, vol.398
, pp. 195-200
-
-
Heo, K.1
Cho, Y.J.2
Cho, K.J.3
Kim, H.W.4
Kim, H.J.5
Shin, H.Y.6
Lee, B.I.7
Kim, G.W.8
-
73
-
-
72249085155
-
Development of multi-electrode array screening for anticonvulsants in acute rat brain slices
-
Hill A.J., Jones N.A., Williams C.M., Stephens G.J., Whalley B.J. Development of multi-electrode array screening for anticonvulsants in acute rat brain slices. J. Neurosci. Methods 2010, 185:246-256.
-
(2010)
J. Neurosci. Methods
, vol.185
, pp. 246-256
-
-
Hill, A.J.1
Jones, N.A.2
Williams, C.M.3
Stephens, G.J.4
Whalley, B.J.5
-
74
-
-
84870498540
-
Cannabidivarin is anticonvulsant in mouse and rat
-
Hill A.J., Mercier M.S., Hill T.D., Glyn S.E., Jones N.A., Yamasaki Y., Futamura T., Duncan M., Stott C.G., Stephens G.J., Williams C.M., Whalley B.J. Cannabidivarin is anticonvulsant in mouse and rat. Br. J. Pharmacol. 2012, 167:1629-1642.
-
(2012)
Br. J. Pharmacol.
, vol.167
, pp. 1629-1642
-
-
Hill, A.J.1
Mercier, M.S.2
Hill, T.D.3
Glyn, S.E.4
Jones, N.A.5
Yamasaki, Y.6
Futamura, T.7
Duncan, M.8
Stott, C.G.9
Stephens, G.J.10
Williams, C.M.11
Whalley, B.J.12
-
75
-
-
83555174546
-
Phytocannabinoids as novel therapeutic agents in CNS disorders
-
Hill A.J., Williams C.M., Whalley B.J., Stephens G.J. Phytocannabinoids as novel therapeutic agents in CNS disorders. Pharmacol. Ther. 2012, 133:79-97.
-
(2012)
Pharmacol. Ther.
, vol.133
, pp. 79-97
-
-
Hill, A.J.1
Williams, C.M.2
Whalley, B.J.3
Stephens, G.J.4
-
76
-
-
84884550462
-
Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism
-
Hill T.D., Cascio M.G., Romano B., Duncan M., Pertwee R.G., Williams C.M., Whalley B.J., Hill A.J. Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism. Br. J. Pharmacol. 2013, 170:679-692.
-
(2013)
Br. J. Pharmacol.
, vol.170
, pp. 679-692
-
-
Hill, T.D.1
Cascio, M.G.2
Romano, B.3
Duncan, M.4
Pertwee, R.G.5
Williams, C.M.6
Whalley, B.J.7
Hill, A.J.8
-
77
-
-
84861349570
-
The extracellular space and epileptic activity in the adult brain: explaining the antiepileptic effects of furosemide and bumetanide
-
Hochman D.W. The extracellular space and epileptic activity in the adult brain: explaining the antiepileptic effects of furosemide and bumetanide. Epilepsia 2012, 53(Suppl. 1):18-25.
-
(2012)
Epilepsia
, vol.53
, pp. 18-25
-
-
Hochman, D.W.1
-
79
-
-
3543092682
-
Minocycline safety and tolerability in Huntington disease
-
Huntington Study Group Minocycline safety and tolerability in Huntington disease. Neurology 2004, 63:547-549.
-
(2004)
Neurology
, vol.63
, pp. 547-549
-
-
-
81
-
-
84924324217
-
Quantitative manganese-enhanced MRI detection of differences between kindling-susceptible and kindling-resistant strains of rats
-
Hutchinson E., Rutecki P., Meyerand E., Sutula T. Quantitative manganese-enhanced MRI detection of differences between kindling-susceptible and kindling-resistant strains of rats. Poster 404.03 Soc. Neurosci. Abstr. 2012, http://www.sfn.org/.
-
(2012)
Poster 404.03 Soc. Neurosci. Abstr.
-
-
Hutchinson, E.1
Rutecki, P.2
Meyerand, E.3
Sutula, T.4
-
82
-
-
84862791691
-
Pitolisant, an inverse agonist of the histamine H3 receptor: an alternative stimulant for narcolepsy-cataplexy in teenagers with refractory sleepiness
-
Inocente C., Arnulf I., Bastuji H., Thibault-Stoll A., Raoux A., Reimão R., Lin J.S., Franco P. Pitolisant, an inverse agonist of the histamine H3 receptor: an alternative stimulant for narcolepsy-cataplexy in teenagers with refractory sleepiness. Clin. Neuropharmacol. 2012, 35:55-60.
-
(2012)
Clin. Neuropharmacol.
, vol.35
, pp. 55-60
-
-
Inocente, C.1
Arnulf, I.2
Bastuji, H.3
Thibault-Stoll, A.4
Raoux, A.5
Reimão, R.6
Lin, J.S.7
Franco, P.8
-
83
-
-
34548024383
-
Tolerability, pharmacokinetics, and neuroendocrine effects of PRX-00023, a novel 5-HT1A agonist, in healthy subjects
-
Iyer G.R., John F., Reinhard J.F., Oshana S., Kauffman M., Donahue S. Tolerability, pharmacokinetics, and neuroendocrine effects of PRX-00023, a novel 5-HT1A agonist, in healthy subjects. J. Clin. Pharmacol. 2007, 47:817-824.
-
(2007)
J. Clin. Pharmacol.
, vol.47
, pp. 817-824
-
-
Iyer, G.R.1
John, F.2
Reinhard, J.F.3
Oshana, S.4
Kauffman, M.5
Donahue, S.6
-
84
-
-
70349189518
-
Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb
-
Izzo A.A., Borrelli F., Capasso R., Di Marzo V., Mechoulam R. Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. Trends Pharmacol. Sci. 2009, 30:515-527.
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 515-527
-
-
Izzo, A.A.1
Borrelli, F.2
Capasso, R.3
Di Marzo, V.4
Mechoulam, R.5
-
85
-
-
76749110725
-
Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo
-
Jones N.A., Hill A.J., Smith I., Bevan S.A., Williams C.M., Whalley B.J., Stephens G.J. Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo. J. Pharmacol. Exp. Ther. 2010, 332:569-577.
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.332
, pp. 569-577
-
-
Jones, N.A.1
Hill, A.J.2
Smith, I.3
Bevan, S.A.4
Williams, C.M.5
Whalley, B.J.6
Stephens, G.J.7
-
86
-
-
84860685529
-
Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
-
Jones N.A., Glynn S.E., Akiyaman S., Hill T.D.M., Hill A.J., Weston S.E., Burnett M.D.A., Yamasaki Y., Stephens G.J., Whalley B.J., Williams C.M. Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures. Seizure 2012, 21:344-352.
-
(2012)
Seizure
, vol.21
, pp. 344-352
-
-
Jones, N.A.1
Glynn, S.E.2
Akiyaman, S.3
Hill, T.D.M.4
Hill, A.J.5
Weston, S.E.6
Burnett, M.D.A.7
Yamasaki, Y.8
Stephens, G.J.9
Whalley, B.J.10
Williams, C.M.11
-
87
-
-
84877610548
-
GABAergic transmission in temporal lobe epilepsy: the role of neurosteroids
-
Joshi S., Rajasekaran K., Kapur J. GABAergic transmission in temporal lobe epilepsy: the role of neurosteroids. Exp. Neurol. 2011, 244:36-42.
-
(2011)
Exp. Neurol.
, vol.244
, pp. 36-42
-
-
Joshi, S.1
Rajasekaran, K.2
Kapur, J.3
-
89
-
-
3042816099
-
Allopregnanolone analogs that positively modulate GABA receptors protect against partial seizures induced by 6-Hz electrical stimulation in mice
-
Kaminski R.M., Livingood M.R., Rogawski M.A. Allopregnanolone analogs that positively modulate GABA receptors protect against partial seizures induced by 6-Hz electrical stimulation in mice. Epilepsia 2004, 45:864-867.
-
(2004)
Epilepsia
, vol.45
, pp. 864-867
-
-
Kaminski, R.M.1
Livingood, M.R.2
Rogawski, M.A.3
-
90
-
-
67349245976
-
Allopregnanolone has no effect on startle response and prepulse inhibition of startle response in patients with premenstrual dysphoric disorder or healthy controls
-
Kask K., Bäckström T., Lundgren P., Sundström Poromaa I. Allopregnanolone has no effect on startle response and prepulse inhibition of startle response in patients with premenstrual dysphoric disorder or healthy controls. Pharmacol. Biochem. Behav. 2009, 92:608-613.
-
(2009)
Pharmacol. Biochem. Behav.
, vol.92
, pp. 608-613
-
-
Kask, K.1
Bäckström, T.2
Lundgren, P.3
Sundström Poromaa, I.4
-
91
-
-
46649113932
-
Allopregnanolone impairs episodic memory in healthy women
-
Kask K., Bäckström T., Nilsson L.G., Sundström-Poromaa I. Allopregnanolone impairs episodic memory in healthy women. Psychopharmacology (Berl) 2008, 199:161-168.
-
(2008)
Psychopharmacology (Berl)
, vol.199
, pp. 161-168
-
-
Kask, K.1
Bäckström, T.2
Nilsson, L.G.3
Sundström-Poromaa, I.4
-
92
-
-
84877314208
-
Efficacy of the histamine 3 receptor (H3R) antagonist pitolisant (formerly known as tiprolisant; BF2.649) in epilepsy: dose-dependent effects in the human photosensitivity model
-
Kasteleijn-Nolst Trenité D., Parain D., Genton P., Masnou P., Schwartz J.C., Hirsch E. Efficacy of the histamine 3 receptor (H3R) antagonist pitolisant (formerly known as tiprolisant; BF2.649) in epilepsy: dose-dependent effects in the human photosensitivity model. Epilepsy Behav. 2013, 28:66-70.
-
(2013)
Epilepsy Behav.
, vol.28
, pp. 66-70
-
-
Kasteleijn-Nolst Trenité, D.1
Parain, D.2
Genton, P.3
Masnou, P.4
Schwartz, J.C.5
Hirsch, E.6
-
93
-
-
9144238050
-
Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity
-
Kenda B.M., Matagne A.C., Talaga P.E., Pasau P.M., Differding E., Lallemand B.I., Frycia A.M., Moureau F.G., Klitgaard H.V., Gillard M.R., Fuks B., Michel P. Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity. J. Med. Chem. 2004, 47:530-549.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 530-549
-
-
Kenda, B.M.1
Matagne, A.C.2
Talaga, P.E.3
Pasau, P.M.4
Differding, E.5
Lallemand, B.I.6
Frycia, A.M.7
Moureau, F.G.8
Klitgaard, H.V.9
Gillard, M.R.10
Fuks, B.11
Michel, P.12
-
94
-
-
0033759542
-
Ganaxolone for treating intractable infantile spasms: a multicenter, open-label, add-on trial
-
Kerrigan J.F., Shields W.D., Nelson T.Y., Bluestone D.L., Dodson W.E., Bourgeois B.F., Pellock J.M., Morton L.D., Monaghan E.P. Ganaxolone for treating intractable infantile spasms: a multicenter, open-label, add-on trial. Epilepsy Res. 2000, 42:133-139.
-
(2000)
Epilepsy Res.
, vol.42
, pp. 133-139
-
-
Kerrigan, J.F.1
Shields, W.D.2
Nelson, T.Y.3
Bluestone, D.L.4
Dodson, W.E.5
Bourgeois, B.F.6
Pellock, J.M.7
Morton, L.D.8
Monaghan, E.P.9
-
96
-
-
0028962088
-
Histamine in cerebrospinal fluid of children with febrile convulsions
-
Kiviranta T., Tuomisto L., Airaksinen E.M. Histamine in cerebrospinal fluid of children with febrile convulsions. Epilepsia 1995, 36:276-280.
-
(1995)
Epilepsia
, vol.36
, pp. 276-280
-
-
Kiviranta, T.1
Tuomisto, L.2
Airaksinen, E.M.3
-
97
-
-
84977566874
-
Safety/tolerability of adjunctive intravenous (IV) brivaracetam (BRV) as infusion or bolus in patients with epilepsy
-
Klein P., Biton V., Dilley D., Barnes M.L., Schiemann J., Lu Z.(S.) Safety/tolerability of adjunctive intravenous (IV) brivaracetam (BRV) as infusion or bolus in patients with epilepsy. Epilepsy Curr. 2014, 14(Suppl. s1):389.
-
(2014)
Epilepsy Curr.
, vol.14
, pp. 389
-
-
Klein, P.1
Biton, V.2
Dilley, D.3
Barnes, M.L.4
Schiemann, J.5
Lu, Z.6
-
98
-
-
0028149787
-
Anticonvulsant activity of neurosteroids: correlation with γ-aminobutyric acid-evoked chloride current potentiation
-
Kokate T.G., Svensson B.E., Rogawski M.A. Anticonvulsant activity of neurosteroids: correlation with γ-aminobutyric acid-evoked chloride current potentiation. J. Pharmacol. Exp. Ther. 1994, 270:1223-1229.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 1223-1229
-
-
Kokate, T.G.1
Svensson, B.E.2
Rogawski, M.A.3
-
99
-
-
0030472538
-
Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice
-
Kokate T.G., Cohen A.L., Karp E., Rogawski M.A. Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice. Neuropharmacology 1996, 35:1049-1056.
-
(1996)
Neuropharmacology
, vol.35
, pp. 1049-1056
-
-
Kokate, T.G.1
Cohen, A.L.2
Karp, E.3
Rogawski, M.A.4
-
100
-
-
33846092175
-
Everolimus drug interactions: application of a classification system for clinical decision making
-
Kovarik J.M., Beyer D., Schmouder R.L. Everolimus drug interactions: application of a classification system for clinical decision making. Biopharm. Drug Dispos. 2006, 27:421-426.
-
(2006)
Biopharm. Drug Dispos.
, vol.27
, pp. 421-426
-
-
Kovarik, J.M.1
Beyer, D.2
Schmouder, R.L.3
-
101
-
-
78049510428
-
Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis
-
Krueger D.A., Care M.M., Holland K., Agricola C., Tudor P., Mangeshkar K.A., Wilson A., Byars T., Sahmoud T., Franz D.N. Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis. N. Engl. J. Med. 2010, 363:1801-1811.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1801-1811
-
-
Krueger, D.A.1
Care, M.M.2
Holland, K.3
Agricola, C.4
Tudor, P.5
Mangeshkar, K.A.6
Wilson, A.7
Byars, T.8
Sahmoud, T.9
Franz, D.N.10
-
102
-
-
84890806945
-
Everolimus treatment of refractory epilepsy in tuberous sclerosis complex
-
Krueger D.A., Wilfong A.A., Holland-Bouley K., Anderson A.E., Agricola K., Tudor C., Mays M., Lopez C.M., Kim M.O., Franz D.N. Everolimus treatment of refractory epilepsy in tuberous sclerosis complex. Ann. Neurol. 2013, 74:679-687.
-
(2013)
Ann. Neurol.
, vol.74
, pp. 679-687
-
-
Krueger, D.A.1
Wilfong, A.A.2
Holland-Bouley, K.3
Anderson, A.E.4
Agricola, K.5
Tudor, C.6
Mays, M.7
Lopez, C.M.8
Kim, M.O.9
Franz, D.N.10
-
103
-
-
84892932590
-
Adjunctive brivaracetam for uncontrolled focal and generalized epilepsies: results of a phase III, double-blind, randomized, placebo-controlled, flexible-dose trial
-
Kwan P., Trinka E., Van P.W., Rektor I., Johnson M.E., Lu S. Adjunctive brivaracetam for uncontrolled focal and generalized epilepsies: results of a phase III, double-blind, randomized, placebo-controlled, flexible-dose trial. Epilepsia 2014, 55:38-46.
-
(2014)
Epilepsia
, vol.55
, pp. 38-46
-
-
Kwan, P.1
Trinka, E.2
Van, P.W.3
Rektor, I.4
Johnson, M.E.5
Lu, S.6
-
105
-
-
84888430082
-
Minocycline exerts acute inhibitory effects on cerebral cortex excitability in humans
-
Lang N., Rothkegel H., Terney D., Antal A., Paulus W. Minocycline exerts acute inhibitory effects on cerebral cortex excitability in humans. Epilepsy Res. 2013, 107:302-305.
-
(2013)
Epilepsy Res.
, vol.107
, pp. 302-305
-
-
Lang, N.1
Rothkegel, H.2
Terney, D.3
Antal, A.4
Paulus, W.5
-
106
-
-
84924324216
-
Unique strains of kindling-susceptible and kindling-resistant rats are behaviorally distinct: evidence background on both seizure-induced plasticity and behavior
-
Langberg T., Miller K., Stafstrom C.E., Sutula T.P. Unique strains of kindling-susceptible and kindling-resistant rats are behaviorally distinct: evidence background on both seizure-induced plasticity and behavior. Poster 447.03 Soc. Neurosci. Abstr. 2012, http://www.sfn.org/.
-
(2012)
Poster 447.03 Soc. Neurosci. Abstr.
-
-
Langberg, T.1
Miller, K.2
Stafstrom, C.E.3
Sutula, T.P.4
-
107
-
-
0033821412
-
Assessment of ganaxolone's anticonvulsant activity using a randomized, double-blind, presurgical trial design
-
Laxer K., Blum D., Abou-Khalil B.W., Morrell M.J., Lee D.A., Data J.L., Monaghan E.P. Assessment of ganaxolone's anticonvulsant activity using a randomized, double-blind, presurgical trial design. Epilepsia 2000, 41:1187-1194. the Ganaxolone Presurgical Study Group.
-
(2000)
Epilepsia
, vol.41
, pp. 1187-1194
-
-
Laxer, K.1
Blum, D.2
Abou-Khalil, B.W.3
Morrell, M.J.4
Lee, D.A.5
Data, J.L.6
Monaghan, E.P.7
-
108
-
-
62949190416
-
A simple quantitative method for analyzing electrographic status epilepticus in rats
-
Lehmkuhle M.J., Thomson K.E., Scheerlinck P., Pouliot W., Greger B., Dudek F.E. A simple quantitative method for analyzing electrographic status epilepticus in rats. J. Neurophysiol. 2009, 101:1660-1670.
-
(2009)
J. Neurophysiol.
, vol.101
, pp. 1660-1670
-
-
Lehmkuhle, M.J.1
Thomson, K.E.2
Scheerlinck, P.3
Pouliot, W.4
Greger, B.5
Dudek, F.E.6
-
109
-
-
35948960395
-
Fructose-1,6-bisphosphate has anticonvulsant activity in models of acute seizures in adult rats
-
Lian X.Y., Khan F.A., Stringer J.L. Fructose-1,6-bisphosphate has anticonvulsant activity in models of acute seizures in adult rats. J. Neurosci. 2007, 27:12007-12011.
-
(2007)
J. Neurosci.
, vol.27
, pp. 12007-12011
-
-
Lian, X.Y.1
Khan, F.A.2
Stringer, J.L.3
-
110
-
-
0023114223
-
Galanin: effects on basal and stimulated insulin and glucagon secretion in the mouse
-
Lindskog S., Ahrén B. Galanin: effects on basal and stimulated insulin and glucagon secretion in the mouse. Acta Physiol. Scand. 1987, 129:305-309.
-
(1987)
Acta Physiol. Scand.
, vol.129
, pp. 305-309
-
-
Lindskog, S.1
Ahrén, B.2
-
111
-
-
0024348129
-
Effects of galanin on insulin and glucagon secretion in the rat
-
Lindskog S., Ahrén B. Effects of galanin on insulin and glucagon secretion in the rat. Int. J. Pancreatol. 1989, 4:335-344.
-
(1989)
Int. J. Pancreatol.
, vol.4
, pp. 335-344
-
-
Lindskog, S.1
Ahrén, B.2
-
112
-
-
0025296281
-
Galanin of the homologous species inhibits insulin secretion in the rat and in the pig
-
Lindskog S., Dunning B.E., Mårtensson H., Ar'Rajab A., Taborsky G.J., Ahrén B. Galanin of the homologous species inhibits insulin secretion in the rat and in the pig. Acta Physiol. Scand. 1990, 139:591-596.
-
(1990)
Acta Physiol. Scand.
, vol.139
, pp. 591-596
-
-
Lindskog, S.1
Dunning, B.E.2
Mårtensson, H.3
Ar'Rajab, A.4
Taborsky, G.J.5
Ahrén, B.6
-
113
-
-
58149269741
-
Mediation of cannabidiol anti-inflammation in the retina by equilibrative nucleoside transporter and A2A adenosine receptor
-
Liou G., Auchampach J.A., Hillard C.J., Zhu G., Yousufzai B., Mian S., Khan S., Khalifa Y. Mediation of cannabidiol anti-inflammation in the retina by equilibrative nucleoside transporter and A2A adenosine receptor. Invest. Ophthalmol. Vis. Sci. 2008, 49:5526-5531.
-
(2008)
Invest. Ophthalmol. Vis. Sci.
, vol.49
, pp. 5526-5531
-
-
Liou, G.1
Auchampach, J.A.2
Hillard, C.J.3
Zhu, G.4
Yousufzai, B.5
Mian, S.6
Khan, S.7
Khalifa, Y.8
-
114
-
-
84924327838
-
Safety and tolerability of adjunctive brivaracetam administered as oral solution in pediatric patients aged at least 1 month to 16 years with epilepsy
-
Liu E., Hepner A., Dilley D., Stockis A., Daniels A. Safety and tolerability of adjunctive brivaracetam administered as oral solution in pediatric patients aged at least 1 month to 16 years with epilepsy. Epilepsy Curr. 2014, 14(Suppl. s1):390-391.
-
(2014)
Epilepsy Curr.
, vol.14
, pp. 390-391
-
-
Liu, E.1
Hepner, A.2
Dilley, D.3
Stockis, A.4
Daniels, A.5
-
115
-
-
84859903461
-
Bumetanide augments the neuroprotective efficacy of phenobarbital plus hypothermia in a neonatal hypoxia-ischemia model
-
Liu Y., Shangguan Y., Barks J.D., Silverstein F.S. Bumetanide augments the neuroprotective efficacy of phenobarbital plus hypothermia in a neonatal hypoxia-ischemia model. Pediatr. Res. 2012, 71:559-565.
-
(2012)
Pediatr. Res.
, vol.71
, pp. 559-565
-
-
Liu, Y.1
Shangguan, Y.2
Barks, J.D.3
Silverstein, F.S.4
-
116
-
-
0030720279
-
The pharmacokinetics of bumetanide in the newborn infant
-
Lopez-Samblas A.M., Adams J.A., Goldberg R.N., Modi M.W. The pharmacokinetics of bumetanide in the newborn infant. Biol. Neonate 1997, 72:265-272.
-
(1997)
Biol. Neonate
, vol.72
, pp. 265-272
-
-
Lopez-Samblas, A.M.1
Adams, J.A.2
Goldberg, R.N.3
Modi, M.W.4
-
117
-
-
84875250685
-
Cation-chloride cotransporters NKCC1 and KCC2 as potential targets for novel antiepileptic and antiepileptogenic treatments
-
Löscher W., Puskarjov M., Kaila K. Cation-chloride cotransporters NKCC1 and KCC2 as potential targets for novel antiepileptic and antiepileptogenic treatments. Neuropharmacology 2013, 69:62-74.
-
(2013)
Neuropharmacology
, vol.69
, pp. 62-74
-
-
Löscher, W.1
Puskarjov, M.2
Kaila, K.3
-
118
-
-
0034457558
-
Serum allopregnanolone levels in pregnant women: changes during pregnancy, at delivery, and in hypertensive patients
-
Luisi S., Petraglia F., Benedetto C., Nappi R.E., Bernardi F., Fadalti M., Reis F.M., Luisi M., Genazzani A.R. Serum allopregnanolone levels in pregnant women: changes during pregnancy, at delivery, and in hypertensive patients. J. Clin. Endocrinol. Metab. 2000, 85:2429-2433.
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 2429-2433
-
-
Luisi, S.1
Petraglia, F.2
Benedetto, C.3
Nappi, R.E.4
Bernardi, F.5
Fadalti, M.6
Reis, F.M.7
Luisi, M.8
Genazzani, A.R.9
-
119
-
-
3042748137
-
The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
-
Lynch B.A., Lambeng N., Nocka K., Kensel-Hammes P., Bajjalieh S.M., Matagne A., Fuks B. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:9861-9866.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 9861-9866
-
-
Lynch, B.A.1
Lambeng, N.2
Nocka, K.3
Kensel-Hammes, P.4
Bajjalieh, S.M.5
Matagne, A.6
Fuks, B.7
-
120
-
-
0034662868
-
The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
-
Malfait A.M., Gallily R., Sumariwalla P.F., Malik A.S., Andreakos E., Mechoulam R., Feldmann M. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:9561-9566.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 9561-9566
-
-
Malfait, A.M.1
Gallily, R.2
Sumariwalla, P.F.3
Malik, A.S.4
Andreakos, E.5
Mechoulam, R.6
Feldmann, M.7
-
121
-
-
0031726154
-
Pharmacokinetics and pharmacodynamics of bumetanide in critically ill pediatric patients
-
Marshall J.D., Wells T.G., Letzig L., Kearns G.L. Pharmacokinetics and pharmacodynamics of bumetanide in critically ill pediatric patients. J. Clin. Pharmacol. 1998, 38:994-1002.
-
(1998)
J. Clin. Pharmacol.
, vol.38
, pp. 994-1002
-
-
Marshall, J.D.1
Wells, T.G.2
Letzig, L.3
Kearns, G.L.4
-
122
-
-
0025024731
-
Histamine receptor-H1, receptor-H2 and receptor-H3 visualized in the brain of human and nonhuman-primates
-
Martinez-Mir M.I., Pollard H., Moreau J., Arrang J.M., Ruat M., Traiffort E., Schwartz J.C., Palacios J.M. Histamine receptor-H1, receptor-H2 and receptor-H3 visualized in the brain of human and nonhuman-primates. Brain Res. 1990, 526:322-327.
-
(1990)
Brain Res.
, vol.526
, pp. 322-327
-
-
Martinez-Mir, M.I.1
Pollard, H.2
Moreau, J.3
Arrang, J.M.4
Ruat, M.5
Traiffort, E.6
Schwartz, J.C.7
Palacios, J.M.8
-
123
-
-
49449094989
-
Anti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A
-
Matagne A., Margineanu D.-G., Kenda B., Michel P., Klitgaard H. Anti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A. Br. J. Pharmacol. 2008, 154:1662-1671.
-
(2008)
Br. J. Pharmacol.
, vol.154
, pp. 1662-1671
-
-
Matagne, A.1
Margineanu, D.-G.2
Kenda, B.3
Michel, P.4
Klitgaard, H.5
-
124
-
-
3042841020
-
Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure-induced neurogenesis in the dentate gyrus
-
Mazarati A., Lu X., Kilk K., Langel U., Wasterlain C., Bartfai T. Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure-induced neurogenesis in the dentate gyrus. Eur. J. Neurosci. 2004, 19:3235-3244.
-
(2004)
Eur. J. Neurosci.
, vol.19
, pp. 3235-3244
-
-
Mazarati, A.1
Lu, X.2
Kilk, K.3
Langel, U.4
Wasterlain, C.5
Bartfai, T.6
-
125
-
-
4444310169
-
Patterns of seizures, hippocampal injury and neurogenesis in three models of status epilepticus in galanin receptor type 1 (GalR1) knockout mice
-
Mazarati A., Lu X., Shinmei S., Badie-Madhavi H., Bartfai T. Patterns of seizures, hippocampal injury and neurogenesis in three models of status epilepticus in galanin receptor type 1 (GalR1) knockout mice. Neuroscience 2004, 128:431-441.
-
(2004)
Neuroscience
, vol.128
, pp. 431-441
-
-
Mazarati, A.1
Lu, X.2
Shinmei, S.3
Badie-Madhavi, H.4
Bartfai, T.5
-
126
-
-
20444413825
-
Regulation of limbic status epilepticus by hippocampal galanin type 1 and type 2 receptors
-
Mazarati A., Lu X. Regulation of limbic status epilepticus by hippocampal galanin type 1 and type 2 receptors. Neuropeptides 2005, 39:277-280.
-
(2005)
Neuropeptides
, vol.39
, pp. 277-280
-
-
Mazarati, A.1
Lu, X.2
-
127
-
-
0019776693
-
Toxicologic evaluation of bumetanide, potent diuretic agent
-
McClain R.M., Dammers K.D. Toxicologic evaluation of bumetanide, potent diuretic agent. J. Clin. Pharmacol. 1981, 21:543-554.
-
(1981)
J. Clin. Pharmacol.
, vol.21
, pp. 543-554
-
-
McClain, R.M.1
Dammers, K.D.2
-
128
-
-
34250626014
-
A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival
-
Meikle L., Talos D.M., Onda H., Pollizzi K., Rotenberg A., Sahin M., Jensen F.E., Kwiatkowski D.J. A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival. J. Neurosci. 2007, 27:5546-5558.
-
(2007)
J. Neurosci.
, vol.27
, pp. 5546-5558
-
-
Meikle, L.1
Talos, D.M.2
Onda, H.3
Pollizzi, K.4
Rotenberg, A.5
Sahin, M.6
Jensen, F.E.7
Kwiatkowski, D.J.8
-
129
-
-
11144354320
-
18F]MPPF-PET study
-
18F]MPPF-PET study. Brain 2004, 127:900-913.
-
(2004)
Brain
, vol.127
, pp. 900-913
-
-
Merlet, I.1
Ostrowsky, K.2
Costes, N.3
Ryvlin, P.4
Isnard, J.5
Faillenot, I.6
Lavenne, F.7
Dufournel, D.8
Le Bars, D.9
Mauguière, F.10
-
130
-
-
77049113736
-
Chronic ingestion of 2-deoxy-d-glucose induces cardiac vacuolization and increases mortality in rats
-
Minor R.K., Smith D.L., Sossang A.M., Kaushik S., Poosala S., Spangler E.L., Roth G.S., Lane M., Allison D.B., deCabo R., Ingraham D., Mattison J.A. Chronic ingestion of 2-deoxy-d-glucose induces cardiac vacuolization and increases mortality in rats. Toxicol. Appl. Pharmacol. 2010, 243:332-339.
-
(2010)
Toxicol. Appl. Pharmacol.
, vol.243
, pp. 332-339
-
-
Minor, R.K.1
Smith, D.L.2
Sossang, A.M.3
Kaushik, S.4
Poosala, S.5
Spangler, E.L.6
Roth, G.S.7
Lane, M.8
Allison, D.B.9
deCabo, R.10
Ingraham, D.11
Mattison, J.A.12
-
131
-
-
0023222060
-
Effects of drugs on the initiation and maintenance of status epilepticus induced by administration of pilocarpine to lithium-pretreated rats
-
Morrisett R.A., Jope R.S., Snead O.C. Effects of drugs on the initiation and maintenance of status epilepticus induced by administration of pilocarpine to lithium-pretreated rats. Exp. Neurol. 1987, 97:193-200.
-
(1987)
Exp. Neurol.
, vol.97
, pp. 193-200
-
-
Morrisett, R.A.1
Jope, R.S.2
Snead, O.C.3
-
132
-
-
0042121318
-
Medicinal chemistry of target family-directed masterkeys
-
Muller G. Medicinal chemistry of target family-directed masterkeys. Drug Discov. Today 2003, 8:681-691.
-
(2003)
Drug Discov. Today
, vol.8
, pp. 681-691
-
-
Muller, G.1
-
133
-
-
58249127284
-
Recent advances in neurobiology of Tuberous Sclerosis Complex
-
Napolioni V., Moavero R., Curatolo P.P. Recent advances in neurobiology of Tuberous Sclerosis Complex. Brain Dev. 2009, 31:104-113.
-
(2009)
Brain Dev.
, vol.31
, pp. 104-113
-
-
Napolioni, V.1
Moavero, R.2
Curatolo, P.P.3
-
134
-
-
84924298475
-
High brain permeability differentiates brivaracetam from levetiracetam and reveals promising potential as acute intervention against prolonged and life threatening seizures
-
Nicolas J., Tytgat D., Matagne A., Staelens L., Klitgaard H., Kervyn S. High brain permeability differentiates brivaracetam from levetiracetam and reveals promising potential as acute intervention against prolonged and life threatening seizures. Epilepsy Curr. 2014, 14:224.
-
(2014)
Epilepsy Curr.
, vol.14
, pp. 224
-
-
Nicolas, J.1
Tytgat, D.2
Matagne, A.3
Staelens, L.4
Klitgaard, H.5
Kervyn, S.6
-
135
-
-
84863886221
-
Effect of gemfibrozil on the metabolism of brivaracetam in vitro and in human subjects
-
Nicolas J.M., Chanteux H., Rosa M., Watanabe S., Stockis A. Effect of gemfibrozil on the metabolism of brivaracetam in vitro and in human subjects. Drug Metab. Dispos. 2012, 40:1466-1472.
-
(2012)
Drug Metab. Dispos.
, vol.40
, pp. 1466-1472
-
-
Nicolas, J.M.1
Chanteux, H.2
Rosa, M.3
Watanabe, S.4
Stockis, A.5
-
136
-
-
84858076505
-
Minocycline as potent anticonvulsant in a patient with astrocytoma and drug resistant epilepsy
-
Nowak M., Strzelczyk A., Reif P.S., Schorlemmer K., Bauer S., Norwood B.A., Oertel W.H., Rosenow F., Strik H., Hamer H.M. Minocycline as potent anticonvulsant in a patient with astrocytoma and drug resistant epilepsy. Seizure 2012, 21:227-228.
-
(2012)
Seizure
, vol.21
, pp. 227-228
-
-
Nowak, M.1
Strzelczyk, A.2
Reif, P.S.3
Schorlemmer, K.4
Bauer, S.5
Norwood, B.A.6
Oertel, W.H.7
Rosenow, F.8
Strik, H.9
Hamer, H.M.10
-
137
-
-
84866143610
-
Behavioral, cognitive, and safety profile of 2-deoxy-2-glucose (2DG) in adult rats
-
Ockuly J.C., Gielissen J.M., Levenick C.V., Zeal C., Groble K., Munsey K., Sutula T.P., Stafstrom C.E. Behavioral, cognitive, and safety profile of 2-deoxy-2-glucose (2DG) in adult rats. Epilepsy Res. 2012, 101:246-252.
-
(2012)
Epilepsy Res.
, vol.101
, pp. 246-252
-
-
Ockuly, J.C.1
Gielissen, J.M.2
Levenick, C.V.3
Zeal, C.4
Groble, K.5
Munsey, K.6
Sutula, T.P.7
Stafstrom, C.E.8
-
138
-
-
43249086546
-
Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors
-
O'Donnell A., Faivre S., Burris H.A., Rea D., Papadimitrakopoulou V., Shand N., Lane H.A., Hazell K., Zoellner U., Kovarik J.M., Brock C., Jones S., Raymond E., Judson I. Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors. J. Clin. Oncol. 2008, 26:1588-1595.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 1588-1595
-
-
O'Donnell, A.1
Faivre, S.2
Burris, H.A.3
Rea, D.4
Papadimitrakopoulou, V.5
Shand, N.6
Lane, H.A.7
Hazell, K.8
Zoellner, U.9
Kovarik, J.M.10
Brock, C.11
Jones, S.12
Raymond, E.13
Judson, I.14
-
139
-
-
84862564038
-
Clinical pharmacology of the loop diuretics furosemide and bumetanide in neonates and infants
-
Pacifici G.M. Clinical pharmacology of the loop diuretics furosemide and bumetanide in neonates and infants. Paediatr. Drugs 2012, 14:233-246.
-
(2012)
Paediatr. Drugs
, vol.14
, pp. 233-246
-
-
Pacifici, G.M.1
-
140
-
-
74149087512
-
Intrathecal huperzine A increases thermal escape latency and decreases flinching behavior in the formalin test in rats
-
Park P., Schachter S., Yaksh T. Intrathecal huperzine A increases thermal escape latency and decreases flinching behavior in the formalin test in rats. Neurosci. Lett. 2010, 470:6-9.
-
(2010)
Neurosci. Lett.
, vol.470
, pp. 6-9
-
-
Park, P.1
Schachter, S.2
Yaksh, T.3
-
142
-
-
0026579057
-
Neuroactive steroids
-
Paul S., Purdy R.H. Neuroactive steroids. FASEB J. 1992, 6:2311-2322.
-
(1992)
FASEB J.
, vol.6
, pp. 2311-2322
-
-
Paul, S.1
Purdy, R.H.2
-
143
-
-
85019504907
-
Treatment with CBD in oily solutions of drug-resistant pediatric epilepsies
-
(Abstract)
-
Pelliccia A., Grssi G., Romano A., Crocchiolo P. Treatment with CBD in oily solutions of drug-resistant pediatric epilepsies. Congress on Cannabis and the Cannabinoids, Leiden, The Netherlands. International Association for Cannabis as Medicine, Third Conference of Cannabis in Medicine 2005, (Abstract).
-
(2005)
Congress on Cannabis and the Cannabinoids, Leiden, The Netherlands. International Association for Cannabis as Medicine, Third Conference of Cannabis in Medicine
-
-
Pelliccia, A.1
Grssi, G.2
Romano, A.3
Crocchiolo, P.4
-
144
-
-
84655166921
-
Effective everolimus treatment of inoperable, life-threatening subependymal giant cell astrocytoma and intractable epilepsy in a patient with tuberous sclerosis complex
-
Perek-Polnik M., Jóźwiak S., Jurkiewicz E., Perek D., Kotulska K. Effective everolimus treatment of inoperable, life-threatening subependymal giant cell astrocytoma and intractable epilepsy in a patient with tuberous sclerosis complex. Eur. J. Paediatr. Neurol. 2011, 16:83-85.
-
(2011)
Eur. J. Paediatr. Neurol.
, vol.16
, pp. 83-85
-
-
Perek-Polnik, M.1
Jóźwiak, S.2
Jurkiewicz, E.3
Perek, D.4
Kotulska, K.5
-
145
-
-
35148899318
-
Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy
-
Pieribone V.A., Tsai J., Soufflet C., Rey E., Shaw K., Giller E., Dulac O. Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy. Epilepsia 2007, 48:1870-1874.
-
(2007)
Epilepsia
, vol.48
, pp. 1870-1874
-
-
Pieribone, V.A.1
Tsai, J.2
Soufflet, C.3
Rey, E.4
Shaw, K.5
Giller, E.6
Dulac, O.7
-
146
-
-
84871999498
-
Electrographic analysis of the effect of sec-butyl-propylacetamide on pharmacoresistant status epilepticus
-
Pouliot W., Bialer M., Hen N., Shekh-Ahmad T., Kaufmann D., Yagen B., Ricks K., Roach B., Nelson C., Dudek F.E. Electrographic analysis of the effect of sec-butyl-propylacetamide on pharmacoresistant status epilepticus. Neuroscience 2013, 231:145-156.
-
(2013)
Neuroscience
, vol.231
, pp. 145-156
-
-
Pouliot, W.1
Bialer, M.2
Hen, N.3
Shekh-Ahmad, T.4
Kaufmann, D.5
Yagen, B.6
Ricks, K.7
Roach, B.8
Nelson, C.9
Dudek, F.E.10
-
147
-
-
84880615536
-
Newly emerging therapies for neonatal seizures
-
Pressler R.M., Mangum B. Newly emerging therapies for neonatal seizures. Semin. Fetal Neonatal Med. 2013, 18:216-223.
-
(2013)
Semin. Fetal Neonatal Med.
, vol.18
, pp. 216-223
-
-
Pressler, R.M.1
Mangum, B.2
-
148
-
-
0029084958
-
Pharmacokinetics of tablet huperzine A in six volunteers
-
Qian B.C., Wang M., Zhou Z.F., Chen K., Zhou R.R., Chen G.S. Pharmacokinetics of tablet huperzine A in six volunteers. Acta Pharmacol. Sin. 1995, 16(3):96-398.
-
(1995)
Acta Pharmacol. Sin.
, vol.16
, Issue.3
, pp. 96-398
-
-
Qian, B.C.1
Wang, M.2
Zhou, Z.F.3
Chen, K.4
Zhou, R.R.5
Chen, G.S.6
-
149
-
-
57849118517
-
Responses to the combination of the glycolytic inhibitor 2-deoxy-glucose (2DG) and docetaxel (DC) in patients with lung and head and neck (H/N) carcinomas
-
ASCO Ann. Meeting Proc.
-
Raez L.E., Langmuir V., Tolba K., Rocha-Lima C.M., Papadopoulos K., Kroll S., Brawer M., Rosenblatt J., Ricart A., Lampidis T. Responses to the combination of the glycolytic inhibitor 2-deoxy-glucose (2DG) and docetaxel (DC) in patients with lung and head and neck (H/N) carcinomas. J. Clin. Oncol. 2007, 25(s18):14025.
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.18 s
, pp. 14025
-
-
Raez, L.E.1
Langmuir, V.2
Tolba, K.3
Rocha-Lima, C.M.4
Papadopoulos, K.5
Kroll, S.6
Brawer, M.7
Rosenblatt, J.8
Ricart, A.9
Lampidis, T.10
-
150
-
-
79955444505
-
Alzheimer's Disease Cooperative Study. A phase II trial of huperzine A in mild to moderate Alzheimer disease
-
Rafii M.S., Walsh S., Little J.T., Behan K., Reynolds B., Ward C., Jin S., Thomas R., Aisen P.S. Alzheimer's Disease Cooperative Study. A phase II trial of huperzine A in mild to moderate Alzheimer disease. Neurology 2011, 76:1389-1394.
-
(2011)
Neurology
, vol.76
, pp. 1389-1394
-
-
Rafii, M.S.1
Walsh, S.2
Little, J.T.3
Behan, K.4
Reynolds, B.5
Ward, C.6
Jin, S.7
Thomas, R.8
Aisen, P.S.9
-
151
-
-
0033714804
-
Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself
-
Reddy D.S., Rogawski M.A. Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself. J. Pharmacol. Exp. Ther. 2000, 295:1241-1248.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 1241-1248
-
-
Reddy, D.S.1
Rogawski, M.A.2
-
152
-
-
84876086923
-
Neurosteroids - endogenous regulators of seizure susceptibility and role in the treatment of epilepsy
-
Oxford University Press, (Chapter 77), J.L. Noebels, M. Avoli, M.A. Rogawski, R.W. Olsen, A.V. Delgado-Escueta (Eds.) Jasper's Basic Mechanisms of the Epilepsies
-
Reddy D.S., Rogawski M.A. Neurosteroids - endogenous regulators of seizure susceptibility and role in the treatment of epilepsy. Contemporary Neurology Series 2012, vol. 80:984-1002. Oxford University Press, (Chapter 77). fourth ed. J.L. Noebels, M. Avoli, M.A. Rogawski, R.W. Olsen, A.V. Delgado-Escueta (Eds.).
-
(2012)
Contemporary Neurology Series
, vol.80
, pp. 984-1002
-
-
Reddy, D.S.1
Rogawski, M.A.2
-
153
-
-
55249093849
-
Excitatory GABA in rodent developing neocortex in vitro
-
Rheims S., Minlebaev M., Ivanov A., Represa A., Khazipov R., Holmes G.L., Ben-Ari Y., Zilberter Y. Excitatory GABA in rodent developing neocortex in vitro. J. Neurophysiol. 2008, 100:609-619.
-
(2008)
J. Neurophysiol.
, vol.100
, pp. 609-619
-
-
Rheims, S.1
Minlebaev, M.2
Ivanov, A.3
Represa, A.4
Khazipov, R.5
Holmes, G.L.6
Ben-Ari, Y.7
Zilberter, Y.8
-
154
-
-
78651321207
-
The serotonin axis: shared mechanisms in seizures, depression, and SUDEP
-
Richerson G.B., Buchanan G.F. The serotonin axis: shared mechanisms in seizures, depression, and SUDEP. Epilepsia 2011, 52(Suppl. 1):28-38.
-
(2011)
Epilepsia
, vol.52
, pp. 28-38
-
-
Richerson, G.B.1
Buchanan, G.F.2
-
155
-
-
40949124826
-
Effects of PRX-00023, a novel, selective serotonin 1A receptor agonist on measures of anxiety and depression in generalized anxiety disorder: results of a double-blind, placebo-controlled trial
-
Rickels K., Mathew S., Banov M.D., Zimbroff D.L., Oshana S., Parsons E.C., Donahue S.R., Kauffman M., Iyer G.R., Reinhard J.F. Effects of PRX-00023, a novel, selective serotonin 1A receptor agonist on measures of anxiety and depression in generalized anxiety disorder: results of a double-blind, placebo-controlled trial. J. Clin. Psychopharmacol. 2008, 28:235-239.
-
(2008)
J. Clin. Psychopharmacol.
, vol.28
, pp. 235-239
-
-
Rickels, K.1
Mathew, S.2
Banov, M.D.3
Zimbroff, D.L.4
Oshana, S.5
Parsons, E.C.6
Donahue, S.R.7
Kauffman, M.8
Iyer, G.R.9
Reinhard, J.F.10
-
156
-
-
77649219653
-
Engineering galanin analogues that discriminate between GalR1 and GalR2 subtypes and exhibit anticonvulsant activity following systemic delivery
-
Robertson C.R., Scholl E.A., Pruess T.H., Green B.R., White H.S., Bulaj G. Engineering galanin analogues that discriminate between GalR1 and GalR2 subtypes and exhibit anticonvulsant activity following systemic delivery. J. Med. Chem. 2010, 53:1871-1875.
-
(2010)
J. Med. Chem.
, vol.53
, pp. 1871-1875
-
-
Robertson, C.R.1
Scholl, E.A.2
Pruess, T.H.3
Green, B.R.4
White, H.S.5
Bulaj, G.6
-
157
-
-
84891501302
-
Neuroactive steroids for the treatment of status epilepticus
-
Rogawski M.A., Loya C.M., Reddy K., Zolkowska D., Lossin C. Neuroactive steroids for the treatment of status epilepticus. Epilepsia 2013, 54(Suppl. 6):93-98.
-
(2013)
Epilepsia
, vol.54
, pp. 93-98
-
-
Rogawski, M.A.1
Loya, C.M.2
Reddy, K.3
Zolkowska, D.4
Lossin, C.5
-
158
-
-
44949208728
-
The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after multiple increasing oral doses in healthy males
-
Rolan P., Sargentini-Maier M.L., Pigeolet E., Stockis A. The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after multiple increasing oral doses in healthy males. Br. J. Clin. Pharmacol. 2008, 66:71-75.
-
(2008)
Br. J. Clin. Pharmacol.
, vol.66
, pp. 71-75
-
-
Rolan, P.1
Sargentini-Maier, M.L.2
Pigeolet, E.3
Stockis, A.4
-
159
-
-
84893488823
-
The pharmacology of imepitoin: the first partial benzodiazepine receptor agonist developed for the treatment of epilepsy
-
Rundfeldt C., Löscher W. The pharmacology of imepitoin: the first partial benzodiazepine receptor agonist developed for the treatment of epilepsy. CNS Drugs 2014, 28:29-43.
-
(2014)
CNS Drugs
, vol.28
, pp. 29-43
-
-
Rundfeldt, C.1
Löscher, W.2
-
160
-
-
84924324213
-
Therapeutic effects of 2DG at the time of injury on fear conditioning and fear context recall at long intervals after TBI in plasticity-susceptible rats
-
Rutecki P., Osting S., Langberg T., Sutula T. Therapeutic effects of 2DG at the time of injury on fear conditioning and fear context recall at long intervals after TBI in plasticity-susceptible rats. Poster 628.13 Soc. Neurosci. Abstr. 2013, http://www.sfn.org/.
-
(2013)
Poster 628.13 Soc. Neurosci. Abstr.
-
-
Rutecki, P.1
Osting, S.2
Langberg, T.3
Sutula, T.4
-
162
-
-
84892935468
-
Adjunctive brivaracetam in adults with uncontrolled focal epilepsy: results from a double-blind, randomized, placebo-controlled trial
-
Ryvlin P., Werhahn K.J., Blaszczyk B., Johnson M.E., Lu S. Adjunctive brivaracetam in adults with uncontrolled focal epilepsy: results from a double-blind, randomized, placebo-controlled trial. Epilepsia 2014, 55:47-56.
-
(2014)
Epilepsia
, vol.55
, pp. 47-56
-
-
Ryvlin, P.1
Werhahn, K.J.2
Blaszczyk, B.3
Johnson, M.E.4
Lu, S.5
-
163
-
-
0037076419
-
Anticonvulsant activity of a nonpeptide galanin receptor agonist
-
Saar K., Mazarati A.M., Mahlapuu R., Hallnemo G., Soomets U., Kilk K., Hellburg S., Pooga M., Tolf B.R., Shi T.S., Hökfelt T., Wasterlain C., Bartfai T., Langel U. Anticonvulsant activity of a nonpeptide galanin receptor agonist. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:7136-7141.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 7136-7141
-
-
Saar, K.1
Mazarati, A.M.2
Mahlapuu, R.3
Hallnemo, G.4
Soomets, U.5
Kilk, K.6
Hellburg, S.7
Pooga, M.8
Tolf, B.R.9
Shi, T.S.10
Hökfelt, T.11
Wasterlain, C.12
Bartfai, T.13
Langel, U.14
-
164
-
-
0032007546
-
Characterization of the in vitro antiepileptic activity of new and old anticonvulsant drugs
-
Sagratella S. Characterization of the in vitro antiepileptic activity of new and old anticonvulsant drugs. Gen. Pharmacol. 1998, 30:153-160.
-
(1998)
Gen. Pharmacol.
, vol.30
, pp. 153-160
-
-
Sagratella, S.1
-
165
-
-
37549020621
-
Pharmacokinetics and metabolism of 14C-brivaracetam, a novel SV2A ligand, in healthy subjects
-
Sargentini-Maier M.L., Espie P., Coquette A., Stockis A. Pharmacokinetics and metabolism of 14C-brivaracetam, a novel SV2A ligand, in healthy subjects. Drug Metab. Dispos. 2008, 36:36-45.
-
(2008)
Drug Metab. Dispos.
, vol.36
, pp. 36-45
-
-
Sargentini-Maier, M.L.1
Espie, P.2
Coquette, A.3
Stockis, A.4
-
166
-
-
34248592717
-
The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after single increasing oral doses in healthy males
-
Sargentini-Maier M.L., Rolan P., Connell J., Tytgat D., Jacobs T., Pigeolet E., Riethuisen J.M., Stockis A. The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after single increasing oral doses in healthy males. Br. J. Clin. Pharmacol. 2007, 63:680-688.
-
(2007)
Br. J. Clin. Pharmacol.
, vol.63
, pp. 680-688
-
-
Sargentini-Maier, M.L.1
Rolan, P.2
Connell, J.3
Tytgat, D.4
Jacobs, T.5
Pigeolet, E.6
Riethuisen, J.M.7
Stockis, A.8
-
167
-
-
84863951068
-
Brivaracetam disposition in renal impairment
-
Sargentini-Maier M.L., Sokalski A., Boulanger P., Jacobs T., Stockis A. Brivaracetam disposition in renal impairment. J. Clin. Pharmacol. 2012, 52:1927-1933.
-
(2012)
J. Clin. Pharmacol.
, vol.52
, pp. 1927-1933
-
-
Sargentini-Maier, M.L.1
Sokalski, A.2
Boulanger, P.3
Jacobs, T.4
Stockis, A.5
-
168
-
-
1942473841
-
Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy
-
Savic I., Lindstrom P., Gulyas B., Halldin C., Andree B., Farde L. Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy. Neurology 2004, 62:1343-1351.
-
(2004)
Neurology
, vol.62
, pp. 1343-1351
-
-
Savic, I.1
Lindstrom, P.2
Gulyas, B.3
Halldin, C.4
Andree, B.5
Farde, L.6
-
169
-
-
84892874222
-
Revisiting the roles of progesterone and allopregnanolone in the nervous system: resurgence of the progesterone receptors
-
Schumacher M., Mattern C., Ghoumari A., Oudinet J.P., Liere P., Labombarda F., Sitruk-Ware R., De Nicola A.F., Guennoun R. Revisiting the roles of progesterone and allopregnanolone in the nervous system: resurgence of the progesterone receptors. Prog. Neurobiol. 2014, 113:6-39.
-
(2014)
Prog. Neurobiol.
, vol.113
, pp. 6-39
-
-
Schumacher, M.1
Mattern, C.2
Ghoumari, A.3
Oudinet, J.P.4
Liere, P.5
Labombarda, F.6
Sitruk-Ware, R.7
De Nicola, A.F.8
Guennoun, R.9
-
170
-
-
79958026433
-
The histamine H3 receptor: from discovery to clinical trials with pitolisant
-
Schwartz J.C. The histamine H3 receptor: from discovery to clinical trials with pitolisant. Br. J. Pharmacol. 2011, 163:713-721.
-
(2011)
Br. J. Pharmacol.
, vol.163
, pp. 713-721
-
-
Schwartz, J.C.1
-
171
-
-
33846223892
-
Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors
-
Scutt A., Williamson E.M. Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors. Calcif. Tissue Int. 2007, 80:50-59.
-
(2007)
Calcif. Tissue Int.
, vol.80
, pp. 50-59
-
-
Scutt, A.1
Williamson, E.M.2
-
172
-
-
84891543694
-
Valnoctamide and sec-propyl-butylacetamide (SPD) for acute seizures and status epielpticus
-
Shekh-Ahmad T., Hen N., McDonough J.H., Yagen B., Bialer M. Valnoctamide and sec-propyl-butylacetamide (SPD) for acute seizures and status epielpticus. Epilepsia 2013, 54(Suppl. 5):98-101.
-
(2013)
Epilepsia
, vol.54
, pp. 98-101
-
-
Shekh-Ahmad, T.1
Hen, N.2
McDonough, J.H.3
Yagen, B.4
Bialer, M.5
-
173
-
-
84894082208
-
Stereoselective anticonvuslant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential
-
Shekh-Ahmad T., Hen N., Yagen B., McDonough J.H., Finnell R.H., Wlodarczyk B., Bialer M. Stereoselective anticonvuslant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential. Epilepsia 2014, 55:353-361.
-
(2014)
Epilepsia
, vol.55
, pp. 353-361
-
-
Shekh-Ahmad, T.1
Hen, N.2
Yagen, B.3
McDonough, J.H.4
Finnell, R.H.5
Wlodarczyk, B.6
Bialer, M.7
-
174
-
-
84863550199
-
Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia
-
Shen H.Y., Singer P., Lytle N., Wei C.J., Lan J.Q., Williams-Karnesky R.L., Chen J.F., Yee B.K., Boison D. Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia. J. Clin. Invest. 2012, 122:2567-2577.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2567-2577
-
-
Shen, H.Y.1
Singer, P.2
Lytle, N.3
Wei, C.J.4
Lan, J.Q.5
Williams-Karnesky, R.L.6
Chen, J.F.7
Yee, B.K.8
Boison, D.9
-
175
-
-
23044507635
-
Optimizing cancer radiotherapy with 2-deoxy-d-glucose: dose escalation studies in patients with glioblastoma multiforme
-
Singh D., Banerji A.K., Dwarakanath B.S., Tripathi R.P., Gupta J.P., Mathew T.L., Ravindranath T., Jain V. Optimizing cancer radiotherapy with 2-deoxy-d-glucose: dose escalation studies in patients with glioblastoma multiforme. Strahlenther. Onkol. 2005, 181:507-514.
-
(2005)
Strahlenther. Onkol.
, vol.181
, pp. 507-514
-
-
Singh, D.1
Banerji, A.K.2
Dwarakanath, B.S.3
Tripathi, R.P.4
Gupta, J.P.5
Mathew, T.L.6
Ravindranath, T.7
Jain, V.8
-
176
-
-
0019941873
-
Neurological and psychiatric side effects of cimetidine - report of 3 cases with review of the literature
-
Sonnenblick M., Rosin A.J., Weissberg N. Neurological and psychiatric side effects of cimetidine - report of 3 cases with review of the literature. Postgrad. Med. J. 1982, 58:415-418.
-
(1982)
Postgrad. Med. J.
, vol.58
, pp. 415-418
-
-
Sonnenblick, M.1
Rosin, A.J.2
Weissberg, N.3
-
177
-
-
84908056755
-
Valnoctamide enhances phasic inhibition: a potential target mechanism for the treatment of benzodiazepine-refractory status epilepticus
-
Spampanato J., Dudek E.F. Valnoctamide enhances phasic inhibition: a potential target mechanism for the treatment of benzodiazepine-refractory status epilepticus. Epilepsia 2014, 10.111/epi.12702.
-
(2014)
Epilepsia
-
-
Spampanato, J.1
Dudek, E.F.2
-
178
-
-
62949110733
-
Novel anticonvulsant and antiepileptic properties of 2-deoxy-d-glucose in experimental epilepsy models
-
Stafstrom C., Ockuly J., Valley M., Roopra A., Sutula T. Novel anticonvulsant and antiepileptic properties of 2-deoxy-d-glucose in experimental epilepsy models. Ann. Neur. 2009, 65:435-448.
-
(2009)
Ann. Neur.
, vol.65
, pp. 435-448
-
-
Stafstrom, C.1
Ockuly, J.2
Valley, M.3
Roopra, A.4
Sutula, T.5
-
179
-
-
77956627000
-
Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies
-
Stein M., Lin H., Jeyamohan C., Dvorzhinski D., Gounder M., Bray K., Eddy S., Goodin S., White E., DiPaola R.S. Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies. Prostate 2010, 70:1388-1394.
-
(2010)
Prostate
, vol.70
, pp. 1388-1394
-
-
Stein, M.1
Lin, H.2
Jeyamohan, C.3
Dvorzhinski, D.4
Gounder, M.5
Bray, K.6
Eddy, S.7
Goodin, S.8
White, E.9
DiPaola, R.S.10
-
180
-
-
84924283901
-
Intravenous dose range finding toxicity of allopregnanolone (ALLO) in neonatal dogs
-
Steinmetz K.L., Rausch L. Intravenous dose range finding toxicity of allopregnanolone (ALLO) in neonatal dogs. Toxicol. Sci. 2013, 132(a1831):389.
-
(2013)
Toxicol. Sci.
, vol.132
, Issue.a1831
, pp. 389
-
-
Steinmetz, K.L.1
Rausch, L.2
-
181
-
-
84892960638
-
Effect of brivaracetam (400mg/day) on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive in healthy women
-
Stockis A., Rolan P. Effect of brivaracetam (400mg/day) on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive in healthy women. J. Clin. Pharmacol. 2013, 53:1313-1321.
-
(2013)
J. Clin. Pharmacol.
, vol.53
, pp. 1313-1321
-
-
Stockis, A.1
Rolan, P.2
-
183
-
-
84896401837
-
Interaction between brivaracetam (100mg/day) and a combination oral contraceptive: a randomized, double-blind, placebo-controlled study
-
Stockis A., Watanabe S., Fauchoux N. Interaction between brivaracetam (100mg/day) and a combination oral contraceptive: a randomized, double-blind, placebo-controlled study. Epilepsia 2014, 55:e27-e31.
-
(2014)
Epilepsia
, vol.55
, pp. e27-e31
-
-
Stockis, A.1
Watanabe, S.2
Fauchoux, N.3
-
184
-
-
84908237589
-
Brivaracetam single and multiple rising oral dose study in healthy Japanese participants: influence of CYP2C19 genotype
-
Stockis A., Watanabe S., Rouits E., Matsuguma K., Irie S. Brivaracetam single and multiple rising oral dose study in healthy Japanese participants: influence of CYP2C19 genotype. Drug Metab. Pharmacokinet. 2014, 9:394-399.
-
(2014)
Drug Metab. Pharmacokinet.
, vol.9
, pp. 394-399
-
-
Stockis, A.1
Watanabe, S.2
Rouits, E.3
Matsuguma, K.4
Irie, S.5
-
185
-
-
0029856835
-
Pharmacokinetics of bumetanide in critically ill infants
-
Sullivan J.E., Witte M.K., Yamashita T.S., Myers C.M., Blumer J.L. Pharmacokinetics of bumetanide in critically ill infants. Clin. Pharmacol. Ther. 1996, 60:405-413.
-
(1996)
Clin. Pharmacol. Ther.
, vol.60
, pp. 405-413
-
-
Sullivan, J.E.1
Witte, M.K.2
Yamashita, T.S.3
Myers, C.M.4
Blumer, J.L.5
-
186
-
-
84872004645
-
Increased expression of TRPV1 in the cortex and hippocampus from patients with mesial temporal lobe epilepsy
-
Sun F.J., Guo W., Zheng D.H., Zhang C.Q., Li S., Liu S.Y., Yin Q., Yang H., Shu H.F. Increased expression of TRPV1 in the cortex and hippocampus from patients with mesial temporal lobe epilepsy. J. Mol. Neurosci. 2013, 49:182-193.
-
(2013)
J. Mol. Neurosci.
, vol.49
, pp. 182-193
-
-
Sun, F.J.1
Guo, W.2
Zheng, D.H.3
Zhang, C.Q.4
Li, S.5
Liu, S.Y.6
Yin, Q.7
Yang, H.8
Shu, H.F.9
-
187
-
-
78650174390
-
Dose-response and time course of action of disease-modifying effects of 2DG on kindling progression: effectiveness of administration after seizures
-
Sutula T., Franzoso S. Dose-response and time course of action of disease-modifying effects of 2DG on kindling progression: effectiveness of administration after seizures. Epilepsia 2008, 49(Suppl. 7):382.
-
(2008)
Epilepsia
, vol.49
, pp. 382
-
-
Sutula, T.1
Franzoso, S.2
-
188
-
-
68549118745
-
Antiepileptic effects of silk-polymer based adenosine release in kindled rats
-
Szybala C., Pritchard E.M., Wilz A., Kaplan D.L., Boison D. Antiepileptic effects of silk-polymer based adenosine release in kindled rats. Exp. Neurol. 2009, 219:126-135.
-
(2009)
Exp. Neurol.
, vol.219
, pp. 126-135
-
-
Szybala, C.1
Pritchard, E.M.2
Wilz, A.3
Kaplan, D.L.4
Boison, D.5
-
189
-
-
0001228360
-
Pharmacological profile of huperzine A, a novel acetylcholinesterase inhibitor from Chinese herb
-
Tang X.C., Han Y.F. Pharmacological profile of huperzine A, a novel acetylcholinesterase inhibitor from Chinese herb. CNS Drug Rev. 2009, 5:281-300.
-
(2009)
CNS Drug Rev.
, vol.5
, pp. 281-300
-
-
Tang, X.C.1
Han, Y.F.2
-
191
-
-
33744456750
-
Pharmacokinetic and behavioral effects of allopregnanolone in healthy women
-
Timby E., Balgard M., Nyberg S., Spigset O., Andersson A., Porankiewicz-Asplund J., Purdy R.H., Zhu D., Bäckström T., Poromaa I.S. Pharmacokinetic and behavioral effects of allopregnanolone in healthy women. Psychopharmacology (Berl.) 2006, 186:414-424.
-
(2006)
Psychopharmacology (Berl.)
, vol.186
, pp. 414-424
-
-
Timby, E.1
Balgard, M.2
Nyberg, S.3
Spigset, O.4
Andersson, A.5
Porankiewicz-Asplund, J.6
Purdy, R.H.7
Zhu, D.8
Bäckström, T.9
Poromaa, I.S.10
-
192
-
-
80955132897
-
A receptor agonist, decreases gonadotropin levels in women. A preliminary study
-
A receptor agonist, decreases gonadotropin levels in women. A preliminary study. Gynecol. Endocrinol. 2011, 27:1087-1093.
-
(2011)
Gynecol. Endocrinol.
, vol.27
, pp. 1087-1093
-
-
Timby, E.1
Hedström, H.2
Bäckström, T.3
Sundström-Poromaa, I.4
Nyberg, S.5
Bixo, M.6
-
193
-
-
84924518312
-
Clinical efficacy and safety of imepitoin in comparison with phenobarbital for the control of idiopathic epilepsy in dogs
-
Tipold A., Keefe T.J., Löscher W., Rundfeldt C., de Vries F. Clinical efficacy and safety of imepitoin in comparison with phenobarbital for the control of idiopathic epilepsy in dogs. J. Vet. Pharmacol. Ther. 2014, (July). 10.1111/jvp.12151.
-
(2014)
J. Vet. Pharmacol. Ther.
, Issue.July
-
-
Tipold, A.1
Keefe, T.J.2
Löscher, W.3
Rundfeldt, C.4
de Vries, F.5
-
194
-
-
0026674117
-
The formalin test: an evaluation of the method
-
Tjolsen A., Berge O.G., Hunskaar J., Roseland H.R., Hole K. The formalin test: an evaluation of the method. Pain 1992, 51:5-17.
-
(1992)
Pain
, vol.51
, pp. 5-17
-
-
Tjolsen, A.1
Berge, O.G.2
Hunskaar, J.3
Roseland, H.R.4
Hole, K.5
-
195
-
-
12244308494
-
PET imaging of 5-HT1A receptor binding in patients with temporal lobe epilepsy
-
Toczek M.T., Carson R.E., Lang L., Ma Y., Spanaki M.V., Der M.G., Fazilat S., Kopylev L., Herscovitch P., Eckelman W.C., Theodore W.H. PET imaging of 5-HT1A receptor binding in patients with temporal lobe epilepsy. Neurology 2003, 60:749-756.
-
(2003)
Neurology
, vol.60
, pp. 749-756
-
-
Toczek, M.T.1
Carson, R.E.2
Lang, L.3
Ma, Y.4
Spanaki, M.V.5
Der, M.G.6
Fazilat, S.7
Kopylev, L.8
Herscovitch, P.9
Eckelman, W.C.10
Theodore, W.H.11
-
197
-
-
0020397052
-
Protein binding and bilirubin displacing properties of bumetanide and furosemide
-
Turmen T., Thom P., Louridas A.T., LeMorvan P., Aranda J.V. Protein binding and bilirubin displacing properties of bumetanide and furosemide. Clin. Pharmacol. 1982, 22:551-556.
-
(1982)
Clin. Pharmacol.
, vol.22
, pp. 551-556
-
-
Turmen, T.1
Thom, P.2
Louridas, A.T.3
LeMorvan, P.4
Aranda, J.V.5
-
198
-
-
0019807732
-
Tuzel Comparison of adverse reactions to bumetanide and furosemide
-
Tuzel Comparison of adverse reactions to bumetanide and furosemide. J Clin. Pharmacol. 1981, 21:615-619.
-
(1981)
J Clin. Pharmacol.
, vol.21
, pp. 615-619
-
-
-
199
-
-
84913531082
-
Successful allopregnanolone treatment of new onset refractory status epilepticus (NORSE) syndrome: first in man experience
-
Vaitkevicius H., Ng M., Moura L., Rosenthal E., Westover M.B., Rosand J., Rogawski M.A., Reddy K., Cole A.J. Successful allopregnanolone treatment of new onset refractory status epilepticus (NORSE) syndrome: first in man experience. Epilepsia 2013, 54(suppl 6):106-124.
-
(2013)
Epilepsia
, vol.54
, pp. 106-124
-
-
Vaitkevicius, H.1
Ng, M.2
Moura, L.3
Rosenthal, E.4
Westover, M.B.5
Rosand, J.6
Rogawski, M.A.7
Reddy, K.8
Cole, A.J.9
-
200
-
-
34249021356
-
Effects of allopregnanolone on sedation in men, and in women on oral contraceptives
-
van Broekhoven F., Bäckström T., van Luijtelaar G., Buitelaar J.K., Smits P., Verke R.J. Effects of allopregnanolone on sedation in men, and in women on oral contraceptives. Psychoneuroendocrinology 2007, 32:555-564.
-
(2007)
Psychoneuroendocrinology
, vol.32
, pp. 555-564
-
-
van Broekhoven, F.1
Bäckström, T.2
van Luijtelaar, G.3
Buitelaar, J.K.4
Smits, P.5
Verke, R.J.6
-
201
-
-
84872056540
-
Efficacy and tolerability of adjunctive brivaracetam in adults with uncontrolled partial-onset seizures: a phase IIb, randomized, controlled trial
-
van Paesschen W., Hirsch E., Johnson M., Falter U., von Rosenstiel P. Efficacy and tolerability of adjunctive brivaracetam in adults with uncontrolled partial-onset seizures: a phase IIb, randomized, controlled trial. Epilepsia 2013, 54:89-97.
-
(2013)
Epilepsia
, vol.54
, pp. 89-97
-
-
van Paesschen, W.1
Hirsch, E.2
Johnson, M.3
Falter, U.4
von Rosenstiel, P.5
-
202
-
-
0036827531
-
Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA(A) receptor in vivo
-
Visser S.A., Gladdines W.W., van der Graaf P.H., Peletier L.A., Danhof M. Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA(A) receptor in vivo. J. Pharmacol. Exp. Ther. 2002, 303:616-626.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.303
, pp. 616-626
-
-
Visser, S.A.1
Gladdines, W.W.2
van der Graaf, P.H.3
Peletier, L.A.4
Danhof, M.5
-
204
-
-
84891543654
-
Brivaracetam
-
Wiley-Blackwell, Chichester, S. Shorvon, E. Perucca, J. Engel (Eds.)
-
von Rosenstiel P., Perucca E. Brivaracetam. The Treatment of Epilepsy 2009, 447-457. Wiley-Blackwell, Chichester. 3rd ed. S. Shorvon, E. Perucca, J. Engel (Eds.).
-
(2009)
The Treatment of Epilepsy
, pp. 447-457
-
-
von Rosenstiel, P.1
Perucca, E.2
-
205
-
-
45949105064
-
Calcium-dependent desensitization of vanilloid receptor TRPV1: a mechanism possibly involved in analgesia induced by topical application of capsaicin
-
Vyklicky L., Novakova-Tousova K., Benedikt J., Samad A., Touska F., Vlachova V. Calcium-dependent desensitization of vanilloid receptor TRPV1: a mechanism possibly involved in analgesia induced by topical application of capsaicin. Physiol. Res. 2008, 57(Suppl. 3):S59-S68.
-
(2008)
Physiol. Res.
, vol.57
, pp. S59-S68
-
-
Vyklicky, L.1
Novakova-Tousova, K.2
Benedikt, J.3
Samad, A.4
Touska, F.5
Vlachova, V.6
-
206
-
-
0023711020
-
The bilirubin-displacing capacity of bumetanide in critically ill babies
-
Walker P.C., Shankaran S. The bilirubin-displacing capacity of bumetanide in critically ill babies. Dev. Pharmacol. Ther. 1988, 11:265-272.
-
(1988)
Dev. Pharmacol. Ther.
, vol.11
, pp. 265-272
-
-
Walker, P.C.1
Shankaran, S.2
-
207
-
-
1842611884
-
Cannabinoids and neuroinflammation
-
Walter L., Stella N. Cannabinoids and neuroinflammation. Br. J. Pharmacol. 2004, 141:775-785.
-
(2004)
Br. J. Pharmacol.
, vol.141
, pp. 775-785
-
-
Walter, L.1
Stella, N.2
-
208
-
-
85027925505
-
Minocycline- and tetracycline-class antibiotics are protective against partial seizures in vivo
-
Wang D.D., Englot D.J., Garcia P.A., Lawton M.T., Young W.L. Minocycline- and tetracycline-class antibiotics are protective against partial seizures in vivo. Epilepsy Behav. 2012, 24:314-318.
-
(2012)
Epilepsy Behav.
, vol.24
, pp. 314-318
-
-
Wang, D.D.1
Englot, D.J.2
Garcia, P.A.3
Lawton, M.T.4
Young, W.L.5
-
209
-
-
45849115460
-
GABA regulates excitatory synapse formation in the neocortex via NMDA receptor activation
-
Wang D.D., Kriegstein A.R. GABA regulates excitatory synapse formation in the neocortex via NMDA receptor activation. J. Neurosci. 2008, 28:5547-5558.
-
(2008)
J. Neurosci.
, vol.28
, pp. 5547-5558
-
-
Wang, D.D.1
Kriegstein, A.R.2
-
210
-
-
0021145816
-
Bumetanide: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use
-
Ward A., Heel R.C. Bumetanide: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use. Drugs 1984, 28:426-464.
-
(1984)
Drugs
, vol.28
, pp. 426-464
-
-
Ward, A.1
Heel, R.C.2
-
211
-
-
84855441268
-
A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage
-
White H.S., Alex A.B., Pollock A., Hen N., Shekh-Ahmed T., Wilcox K.S., McDonough J.H., Stables J.P., Kaufmann D., Yagen B., Bialer M. A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage. Epilepsia 2012, 53:134-146.
-
(2012)
Epilepsia
, vol.53
, pp. 134-146
-
-
White, H.S.1
Alex, A.B.2
Pollock, A.3
Hen, N.4
Shekh-Ahmed, T.5
Wilcox, K.S.6
McDonough, J.H.7
Stables, J.P.8
Kaufmann, D.9
Yagen, B.10
Bialer, M.11
-
212
-
-
33846216571
-
Anticonvulsant activity of Huperzine A, an alkaloid extract of Chinese club moss (Huperzia serrata)
-
White H.S., Schachter S., Lee D., Xiaoshen J., Eisenberg D. Anticonvulsant activity of Huperzine A, an alkaloid extract of Chinese club moss (Huperzia serrata). Epilepsia 2005, 46(Suppl. 8):220.
-
(2005)
Epilepsia
, vol.46
, pp. 220
-
-
White, H.S.1
Schachter, S.2
Lee, D.3
Xiaoshen, J.4
Eisenberg, D.5
-
213
-
-
84887989959
-
Verolimus in tuberous sclerosis patients with intractable epilepsy: a treatment option?
-
Wiegand G., May T.W., Ostertag P., Boor R., Stephani U., Franz D.N. Verolimus in tuberous sclerosis patients with intractable epilepsy: a treatment option?. Eur. J. Paediatr. Neurol. 2013, 17:631-638.
-
(2013)
Eur. J. Paediatr. Neurol.
, vol.17
, pp. 631-638
-
-
Wiegand, G.1
May, T.W.2
Ostertag, P.3
Boor, R.4
Stephani, U.5
Franz, D.N.6
-
214
-
-
0025987983
-
Anxiolytic activity of the progesterone metabolite 5 alpha-pregnan-3 alpha-o1-20-one
-
Wieland S., Lan N.C., Mirasedeghi S., Gee K.W. Anxiolytic activity of the progesterone metabolite 5 alpha-pregnan-3 alpha-o1-20-one. Brain Res. 1991, 565:263-268.
-
(1991)
Brain Res.
, vol.565
, pp. 263-268
-
-
Wieland, S.1
Lan, N.C.2
Mirasedeghi, S.3
Gee, K.W.4
-
215
-
-
84879710932
-
Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis
-
Williams-Karnesky R.L., Sandau U.S., Lusardi T.A., Lytle N.K., Farrell J.M., Pritchard E.M., Kaplan D.L., Boison D. Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis. J. Clin. Invest. 2013, 123:3552-3563.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3552-3563
-
-
Williams-Karnesky, R.L.1
Sandau, U.S.2
Lusardi, T.A.3
Lytle, N.K.4
Farrell, J.M.5
Pritchard, E.M.6
Kaplan, D.L.7
Boison, D.8
-
216
-
-
46149117721
-
Silk polymer-based adenosine release: therapeutic potential for epilepsy
-
Wilz A., Pritchard E.M., Li T., Lan J.Q., Kaplan D.L., Boison D. Silk polymer-based adenosine release: therapeutic potential for epilepsy. Biomaterials 2008, 29:3609-3616.
-
(2008)
Biomaterials
, vol.29
, pp. 3609-3616
-
-
Wilz, A.1
Pritchard, E.M.2
Li, T.3
Lan, J.Q.4
Kaplan, D.L.5
Boison, D.6
-
217
-
-
0004052706
-
Improving effects of huperzine A on spatial working memory in aged monkeys and young adult monkeys with experimental cognitive impairment
-
Ye J.W., Cai J.X., Wang L.M., Tang X.C. Improving effects of huperzine A on spatial working memory in aged monkeys and young adult monkeys with experimental cognitive impairment. J. Pharmacol. Exp. Ther. 1999, 288:814-819.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.288
, pp. 814-819
-
-
Ye, J.W.1
Cai, J.X.2
Wang, L.M.3
Tang, X.C.4
-
218
-
-
84874228911
-
Alleviation of chronic pain following rat spinal cord compression injury with multimodal actions of huperzine A
-
Yu D., Thakor D.K., Han I., Ropper A.E., Haragopal H., Sidman R.L., Zafonte R., Schachter S.C., Teng Y.D. Alleviation of chronic pain following rat spinal cord compression injury with multimodal actions of huperzine A. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:E746-E755.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. E746-E755
-
-
Yu, D.1
Thakor, D.K.2
Han, I.3
Ropper, A.E.4
Haragopal, H.5
Sidman, R.L.6
Zafonte, R.7
Schachter, S.C.8
Teng, Y.D.9
-
219
-
-
42949140259
-
Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
-
Zeng L.H., Xu L., Gutmann D.H., Wong M. Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex. Ann. Neurol. 2008, 63:444-453.
-
(2008)
Ann. Neurol.
, vol.63
, pp. 444-453
-
-
Zeng, L.H.1
Xu, L.2
Gutmann, D.H.3
Wong, M.4
-
220
-
-
0037189932
-
Huperzine A attenuates apoptosis and mitochondria-dependent caspase-3 in rat cortical neurons
-
Zhou J., Tang T. Huperzine A attenuates apoptosis and mitochondria-dependent caspase-3 in rat cortical neurons. FEBS Lett. 2002, 526:21-25.
-
(2002)
FEBS Lett.
, vol.526
, pp. 21-25
-
-
Zhou, J.1
Tang, T.2
-
221
-
-
0035834265
-
Huperzine A attenuates cognitive deficits and hippocampal neuronal damage after transient global ischemia in gerbils
-
Zhou J., Zhang H.Y., Tang X.C. Huperzine A attenuates cognitive deficits and hippocampal neuronal damage after transient global ischemia in gerbils. Neurosci. Lett. 2001, 313:137-140.
-
(2001)
Neurosci. Lett.
, vol.313
, pp. 137-140
-
-
Zhou, J.1
Zhang, H.Y.2
Tang, X.C.3
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