Alleviation of chronic pain following rat spinal cord compression injury with multimodal actions of huperzine A

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 8, 2013, Pages

  Yu, Dou ^a,b   Thakor, Devang K ^a,b   Han, Inbo ^a,b   Ropper, Alexander E ^a,b   Haragopal, Hariprakash ^a,b   Sidman, Richard L ^c   Zafonte, Ross ^d   Schachter, Steven C ^c,e   Teng, Yang D ^a,b,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b VA BOSTON HEALTHCARE SYSTEM   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d and Red Sox Foundation and Massachusetts General Hospital Home Base Program   (United States)

^e Center for Integration of Medicine and Innovative Technology   (United States)

Author keywords

Botanical medicine; Hyperalgesia

Indexed keywords

ACETYLCHOLINESTERASE; AMPA RECEPTOR; HUPERZINE A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN HOMER 1A;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BODY WEIGHT; BOLUS INJECTION; CHOLINERGIC ACTIVITY; CHOLINERGIC NERVE CELL; CHOLINERGIC SYSTEM; CHRONIC PAIN; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; HISTOPATHOLOGY; HUPERZIA; IMMUNOCYTOCHEMISTRY; INTERNEURON; LONG TERM CARE; MICROGLIA; MUSCLE SPASM; NERVOUS SYSTEM INFLAMMATION; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL CORD COMPRESSION; SPINAL CORD DORSAL HORN; THORACIC SPINAL CORD; UPREGULATION;

ALKALOIDS; ANIMALS; BEHAVIOR, ANIMAL; FEMALE; PAIN; RATS; RATS, SPRAGUE-DAWLEY; SESQUITERPENES; SPINAL CORD COMPRESSION;

EID: 84874228911     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1300083110     Document Type: Article

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