Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery

Journal of Medicinal Chemistry

Volumn 53, Issue 4, 2010, Pages 1871-1875

  Robertson, Charles R ^a   Scholl, Erika Adkins ^a   Pruess, Timothy H ^a   Green, Brad R ^a   White, H Steve ^a   Bulaj, Grzegorz ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GALANIN DERIVATIVE; GALANIN RECEPTOR 1; GALANIN RECEPTOR 2; N METHYLTRYPTOPHAN; NAX 5055; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN SYNTHESIS; SEIZURE;

AMINO ACID SEQUENCE; ANIMALS; ANTICONVULSANTS; CALCIUM; GALANIN; HUMANS; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; RADIOLIGAND ASSAY; RATS; RECEPTOR, GALANIN, TYPE 1; RECEPTOR, GALANIN, TYPE 2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77649219653     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm9018349     Document Type: Article

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