Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy

Epilepsia

Volumn 48, Issue 10, 2007, Pages 1870-1874

  Pieribone, Vincent A ^a,b,c   Tsai, Julia ^a   Soufflet, Christine ^d   Rey, Elisabeth ^g   Shaw, Ken ^a   Giller, Earl ^a,c   Dulac, Olivier ^d,e,f  

^a Marinus Pharmaceuticals Inc   (United States)

^b JOHN B PIERCE LABORATORY   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

^e INSERM   (France)

^f UNIVERSITÉ PARIS DESCARTES   (France)

^g HÔPITAL SAINT VINCENT DE PAUL   (France)

Author keywords

Allopregnanolone; Anticonvulsant; Infantile spasms; Neurosteroid; West syndrome

Indexed keywords

ANTICONVULSIVE AGENT; BETA CYCLODEXTRIN; CLOBAZAM; GANAXOLONE;

ADD ON THERAPY; ADOLESCENT; AGITATION; ANTICONVULSANT ACTIVITY; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL EVALUATION; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVULSION; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG DOSE TITRATION; DRUG MEGADOSE; DRUG TOLERABILITY; DRUG WITHDRAWAL; EXCITATION; FEMALE; FOCAL EPILEPSY; GENERALIZED EPILEPSY; HALLUCINATION; HOSTILITY; HUMAN; MALE; PATIENT COMPLIANCE; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINGLE BLIND PROCEDURE; SOMNOLENCE; TREATMENT RESPONSE;

ADOLESCENT; AGE FACTORS; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; EPILEPSY; FEMALE; HUMANS; MALE; PILOT PROJECTS; PREGNANOLONE; TREATMENT OUTCOME;

EID: 35148899318     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2007.01182.x     Document Type: Article

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