메뉴 건너뛰기




Volumn 17, Issue 6, 2013, Pages 631-638

Everolimus in tuberous sclerosis patients with intractable epilepsy: A treatment option?

Author keywords

Everolimus; Intractable epilepsy; mTOR; Refractory seizures; Tuberous sclerosis

Indexed keywords

EVEROLIMUS;

EID: 84887989959     PISSN: 10903798     EISSN: 15322130     Source Type: Journal    
DOI: 10.1016/j.ejpn.2013.06.002     Document Type: Article
Times cited : (78)

References (35)
  • 1
    • 84867101893 scopus 로고    scopus 로고
    • Management of epilepsy associated with tuberous sclerosis complex (TSC): Clinical recommendations
    • On behalf of the participants of the TSC Consensus Meeting for SEGA und Epilepsy Management 10.1016/j.ejpn.2012.05.004
    • P. Curatolo, S. Jozwiak, R. Nabbout On behalf of the participants of the TSC Consensus Meeting for SEGA und Epilepsy Management Management of epilepsy associated with tuberous sclerosis complex (TSC): clinical recommendations Eur J Paediatr Neurol 16 2012 582 586 10.1016/j.ejpn.2012.05.004
    • (2012) Eur J Paediatr Neurol , vol.16 , pp. 582-586
    • Curatolo, P.1    Jozwiak, S.2    Nabbout, R.3
  • 2
    • 42949140259 scopus 로고    scopus 로고
    • Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
    • L.H. Zeng, L. Xu, D.H. Gutmann, and M. Wong Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex Ann Neurol 63 2008 444 453
    • (2008) Ann Neurol , vol.63 , pp. 444-453
    • Zeng, L.H.1    Xu, L.2    Gutmann, D.H.3    Wong, M.4
  • 3
    • 80052313178 scopus 로고    scopus 로고
    • Everolimus: An mTOR inhibitor for the treatment of tuberous sclerosis
    • D.N. Franz Everolimus: an mTOR inhibitor for the treatment of tuberous sclerosis Expert Rev Anticancer Ther 11 8 2011 1181 1192
    • (2011) Expert Rev Anticancer Ther , vol.11 , Issue.8 , pp. 1181-1192
    • Franz, D.N.1
  • 4
    • 84873653141 scopus 로고    scopus 로고
    • Everolimus long-term safety and efficacy in subependymal giant-cell astrocytoma
    • D.A. Krueger, M.M. Care, K. Agricola, C. Tudor, M. Mays, and D.N. Franz Everolimus long-term safety and efficacy in subependymal giant-cell astrocytoma Neurology 80 2013 574 580
    • (2013) Neurology , vol.80 , pp. 574-580
    • Krueger, D.A.1    Care, M.M.2    Agricola, K.3    Tudor, C.4    Mays, M.5    Franz, D.N.6
  • 5
    • 83455164990 scopus 로고    scopus 로고
    • Everolimus: In patients with subependymal giant cell astrocytoma associated with tuberous sclerosis complex
    • M.P. Curran Everolimus: in patients with subependymal giant cell astrocytoma associated with tuberous sclerosis complex Paediatr Drugs 14 1 2012 51 60
    • (2012) Paediatr Drugs , vol.14 , Issue.1 , pp. 51-60
    • Curran, M.P.1
  • 6
    • 84655166921 scopus 로고    scopus 로고
    • Effective everolimus treatment of inoperable, life-threatening subependymal giant cell astrocytoma and intractable epilepsy in patient with tuberous sclerosis complex
    • M. Perek-Polnik, S. Jozwiak, E. Jurkiewicz, D. Perek, and K. Kotulska Effective everolimus treatment of inoperable, life-threatening subependymal giant cell astrocytoma and intractable epilepsy in patient with tuberous sclerosis complex Eur J Paediatr Neurol 16 2012 83 85
    • (2012) Eur J Paediatr Neurol , vol.16 , pp. 83-85
    • Perek-Polnik, M.1    Jozwiak, S.2    Jurkiewicz, E.3    Perek, D.4    Kotulska, K.5
  • 7
    • 64249118425 scopus 로고    scopus 로고
    • Rapamycin reduces seizure frequency in tuberous sclerosis complex
    • J. Muncy, I.J. Butler, and M.K. Koening Rapamycin reduces seizure frequency in tuberous sclerosis complex J Child Neurol 24 4 2009 477
    • (2009) J Child Neurol , vol.24 , Issue.4 , pp. 477
    • Muncy, J.1    Butler, I.J.2    Koening, M.K.3
  • 9
    • 28044456974 scopus 로고    scopus 로고
    • Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2
    • S.F. Tavazoie, V.A. Alvarez, D.A. Ridenour, D.J. Kwiatkowski, and B.L. Sabatini Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2 Nat Neurosci 8 12 2005 Dec 1727 1734
    • (2005) Nat Neurosci , vol.8 , Issue.12 , pp. 1727-1734
    • Tavazoie, S.F.1    Alvarez, V.A.2    Ridenour, D.A.3    Kwiatkowski, D.J.4    Sabatini, B.L.5
  • 10
    • 84858136146 scopus 로고    scopus 로고
    • Everolimus alters white matter diffusion in tuberous sclerosis complex
    • J.M. Tillema, J.L. Leach, D.A. Krueger, and D.N. Franz Everolimus alters white matter diffusion in tuberous sclerosis complex Neurology 78 8 2012 Feb 21 526 531
    • (2012) Neurology , vol.78 , Issue.8 , pp. 526-531
    • Tillema, J.M.1    Leach, J.L.2    Krueger, D.A.3    Franz, D.N.4
  • 11
    • 84865630995 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) inhibition: Potential for antiseizure, antiepileptogenic, and epileptostatic therapy
    • R.C. Ryther, and M. Wong Mammalian target of rapamycin (mTOR) inhibition: potential for antiseizure, antiepileptogenic, and epileptostatic therapy Curr Neurol Neurosci Rep 12 4 2012 Aug 410 418
    • (2012) Curr Neurol Neurosci Rep , vol.12 , Issue.4 , pp. 410-418
    • Ryther, R.C.1    Wong, M.2
  • 12
    • 84877338156 scopus 로고    scopus 로고
    • Crino PB mTOR and epileptogenesis in developmental brain malformations
    • J.L. Noebels, M. Avoli, M.A. Rogawski, R.W. Olsen, A.V. Delgado-Escueta, 4th ed. National Center for Biotechnology Information (US) Bethesda (MD)
    • M. Wong Crino PB mTOR and epileptogenesis in developmental brain malformations J.L. Noebels, M. Avoli, M.A. Rogawski, R.W. Olsen, A.V. Delgado-Escueta, Jasper's basic mechanisms of the epilepsies 4th ed. 2012 National Center for Biotechnology Information (US) Bethesda (MD)
    • (2012) Jasper's Basic Mechanisms of the Epilepsies
    • Wong, M.1
  • 14
    • 0032438210 scopus 로고    scopus 로고
    • Tuberous sclerosis consensus conference: Revised clinical diagnostic criteria
    • E.S. Roach, M.R. Gomez, and H. Northrup Tuberous sclerosis consensus conference: revised clinical diagnostic criteria J Child Neurol 13 1998 624 628
    • (1998) J Child Neurol , vol.13 , pp. 624-628
    • Roach, E.S.1    Gomez, M.R.2    Northrup, H.3
  • 17
    • 77249092260 scopus 로고    scopus 로고
    • Der elektronische Behandlungskalender (Epivista)
    • G. Rabending, and U. Runge Der elektronische Behandlungskalender (Epivista) Z für Epileptologie 15 2002 2 5
    • (2002) Z für Epileptologie , vol.15 , pp. 2-5
    • Rabending, G.1    Runge, U.2
  • 20
    • 0002605320 scopus 로고
    • Some quick sign tests for trend in location and dispersion
    • D.R. Cox, and A. Stuart Some quick sign tests for trend in location and dispersion Biometrika 42 1955 80 95
    • (1955) Biometrika , vol.42 , pp. 80-95
    • Cox, D.R.1    Stuart, A.2
  • 21
    • 0025172155 scopus 로고
    • Some covariance models for longitudinal count data with overdispersion
    • P.F. Thall, and S.C. Vail Some covariance models for longitudinal count data with overdispersion Biometrics 46 1990 657 671
    • (1990) Biometrics , vol.46 , pp. 657-671
    • Thall, P.F.1    Vail, S.C.2
  • 22
    • 20044375557 scopus 로고    scopus 로고
    • Intractable seizures in tuberous sclerosis complex: From molecular pathogenesis to the rationale for treatment
    • P. Curatolo, R. Bombardieri, M. Verdecchia, and S. Seri Intractable seizures in tuberous sclerosis complex: from molecular pathogenesis to the rationale for treatment J Child Neurol 20 2005 318 325
    • (2005) J Child Neurol , vol.20 , pp. 318-325
    • Curatolo, P.1    Bombardieri, R.2    Verdecchia, M.3    Seri, S.4
  • 23
    • 84874746597 scopus 로고    scopus 로고
    • Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): A multicentre, randomised, double-blind, placebo-controlled trial
    • J.J. Bissler, J.C. Kingswood, and E. Radzikowska Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial Lancet 381 2013 Mar 9 817 824
    • (2013) Lancet , vol.381 , pp. 817-824
    • Bissler, J.J.1    Kingswood, J.C.2    Radzikowska, E.3
  • 24
    • 84872088946 scopus 로고    scopus 로고
    • Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): A multicentre, randomised, placebo-controlled phase 3 trial
    • D.N. Franz, E. Belousova, and S. Sparagana Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial Lancet 381 9861 2013 Jan 12 125 132
    • (2013) Lancet , vol.381 , Issue.9861 , pp. 125-132
    • Franz, D.N.1    Belousova, E.2    Sparagana, S.3
  • 25
    • 33644839539 scopus 로고    scopus 로고
    • Diarrhea in American infants and young children in the community setting: Incidence, clinical presentation and microbiology
    • L. Vernacchio, R. Vezina, A.A. Mitchell, S.M. Lesko, A.G. Plaut, and W.K. David Diarrhea in American infants and young children in the community setting: incidence, clinical presentation and microbiology Pediatr Infect Dis J 25 1 2006 2 7
    • (2006) Pediatr Infect Dis J , vol.25 , Issue.1 , pp. 2-7
    • Vernacchio, L.1    Vezina, R.2    Mitchell, A.A.3    Lesko, S.M.4    Plaut, A.G.5    David, W.K.6
  • 27
    • 84881310154 scopus 로고    scopus 로고
    • Long-term effect of everolimus on epilepsy and growth in children under 3 years of age treated for subependymal giant cell astrocytoma associated with tuberous sclerosis complex
    • 10.1016/j.ejpn.2013.03.002
    • K. Kotulska, D. Chmielewski, J. Borkowska, E. Jurkiewicz, D. Kuczyński, T. Kmieć, B. Lojszczyk, D. Dunin-Wa̧sowicz, and S. Jóźwiak Long-term effect of everolimus on epilepsy and growth in children under 3 years of age treated for subependymal giant cell astrocytoma associated with tuberous sclerosis complex Eur J Paediatr Neurol 2013 Apr 6 10.1016/j.ejpn.2013.03.002
    • (2013) Eur J Paediatr Neurol
    • Kotulska, K.1    Chmielewski, D.2    Borkowska, J.3    Jurkiewicz, E.4    Kuczyński, D.5    Kmieć, T.6    Lojszczyk, B.7    Dunin-Wa̧sowicz, D.8    Jóźwiak, S.9
  • 28
    • 45849110311 scopus 로고    scopus 로고
    • Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: Effects on mTORC1 and Akt signaling lead to improved survival and function
    • L. Meikle, K. Pollizzi, A. Egnor, I. Kramvis, H. Lane, M. Sahin, and D.J. Kwiatkowski Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function J Neurosci 28 21 2008 May 21 5422 5432
    • (2008) J Neurosci , vol.28 , Issue.21 , pp. 5422-5432
    • Meikle, L.1    Pollizzi, K.2    Egnor, A.3    Kramvis, I.4    Lane, H.5    Sahin, M.6    Kwiatkowski, D.J.7
  • 29
    • 84863727156 scopus 로고    scopus 로고
    • Finding a better drug for epilepsy: The mTOR pathway as an antiepileptogenic target
    • A.S. Galanopoulou, J.A. Gorter, and C. Cepeda Finding a better drug for epilepsy: the mTOR pathway as an antiepileptogenic target Epilepsia 53 7 2012 Jul 1119 1130
    • (2012) Epilepsia , vol.53 , Issue.7 , pp. 1119-1130
    • Galanopoulou, A.S.1    Gorter, J.A.2    Cepeda, C.3
  • 30
    • 76249084241 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) inhibition as a potential anti-epileptogenic therapy: From tuberous sclerosis to common acquired epilepsies
    • M. Wong Mammalian target of rapamycin (mTOR) inhibition as a potential anti-epileptogenic therapy: from tuberous sclerosis to common acquired epilepsies Epilepsia 51 1 2010 27 36
    • (2010) Epilepsia , vol.51 , Issue.1 , pp. 27-36
    • Wong, M.1
  • 31
    • 84874243165 scopus 로고    scopus 로고
    • Vigabatrin inhibits seizures and mTOR pathway activation in a mouse model of tuberous sclerosis complex
    • Epub 2013 Feb 20
    • B. Zhang, S.S. McDaniel, N.R. Rensing, and M. Wong Vigabatrin inhibits seizures and mTOR pathway activation in a mouse model of tuberous sclerosis complex PLoS One 8 2 2013 Epub 2013 Feb 20
    • (2013) PLoS One , vol.8 , Issue.2
    • Zhang, B.1    McDaniel, S.S.2    Rensing, N.R.3    Wong, M.4
  • 32
    • 79952570329 scopus 로고    scopus 로고
    • The ketogenic diet inhibits the mammalian target of apamycin (mTOR) pathway
    • S.S. McDaniel, N.R. Rensing, L.L. Thio, K.A. Yamada, and M. Wong The ketogenic diet inhibits the mammalian target of apamycin (mTOR) pathway Epilepsia 52 3 2011 Mar e7 e11
    • (2011) Epilepsia , vol.52 , Issue.3
    • McDaniel, S.S.1    Rensing, N.R.2    Thio, L.L.3    Yamada, K.A.4    Wong, M.5
  • 34
    • 79958184395 scopus 로고    scopus 로고
    • A pulse rapamycin therapy for infantile spasms and associated cognitive decline
    • E. Raffo, A. Coppola, T. Ono, S.W. Briggs, and A.S. Galanopoulou A pulse rapamycin therapy for infantile spasms and associated cognitive decline Neurobiol Dis 43 2 2011 Aug 322 329
    • (2011) Neurobiol Dis , vol.43 , Issue.2 , pp. 322-329
    • Raffo, E.1    Coppola, A.2    Ono, T.3    Briggs, S.W.4    Galanopoulou, A.S.5
  • 35
    • 33644683295 scopus 로고    scopus 로고
    • Glutamatergic regulation of the p70S6 kinase in primary mouse neurons
    • G. Lenz, and J. Avruch Glutamatergic regulation of the p70S6 kinase in primary mouse neurons J Biol Chem 280 46 2005 Nov 18 38121 38124
    • (2005) J Biol Chem , vol.280 , Issue.46 , pp. 38121-38124
    • Lenz, G.1    Avruch, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.