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Volumn 181, Issue 8, 2005, Pages 507-514

Optimizing cancer radiotherapy with 2-deoxy-D-glucose: Dose escalation studies in patients with glioblastoma multiforme

Author keywords

2 deoxy D glucose; Dose escalation; Glioblastoma multiforme; Radiotherapy; Safety and tolerance

Indexed keywords

DEOXYGLUCOSE; FUROSEMIDE; MANNITOL;

EID: 23044507635     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00066-005-1320-z     Document Type: Article
Times cited : (229)

References (60)
  • 1
    • 0027761378 scopus 로고
    • Glioblastoma revisited: Do clinical observations match basic science theory? Radiosurgery: clinical observations
    • Alexander E 3rd. Glioblastoma revisited: do clinical observations match basic science theory? Radiosurgery: clinical observations. J Neurooncol 1993;15:169-73.
    • (1993) J Neurooncol , vol.15 , pp. 169-173
    • Alexander III, E.1
  • 2
    • 0028158474 scopus 로고
    • Brain tumour protocols in North America
    • Bernstien M, Rutka J. Brain tumour protocols in North America. J Neurooncol 1993;17:231-51.
    • (1993) J Neurooncol , vol.17 , pp. 231-251
    • Bernstien, M.1    Rutka, J.2
  • 3
    • 0023132221 scopus 로고
    • Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription
    • Birnbaum MJ, Haspel HC, Rosen OM. Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription. Science 1987;235:1495-8.
    • (1987) Science , vol.235 , pp. 1495-1498
    • Birnbaum, M.J.1    Haspel, H.C.2    Rosen, O.M.3
  • 4
    • 0033079597 scopus 로고    scopus 로고
    • Oncogenic alterations of metabolism
    • Dang CV, Semenza GL. Oncogenic alterations of metabolism. Trends Biochem Sci 1999;24:68-72.
    • (1999) Trends Biochem Sci , vol.24 , pp. 68-72
    • Dang, C.V.1    Semenza, G.L.2
  • 5
    • 0021359372 scopus 로고
    • Issues in the in vivo measurement of glucose metabolism of human central nervouus system tumours
    • Dichiro G, Brooks RA, Patronas NT, et al. Issues in the in vivo measurement of glucose metabolism of human central nervouus system tumours. Ann Neurol 1984;15:S138-46.
    • (1984) Ann Neurol , vol.15
    • Dichiro, G.1    Brooks, R.A.2    Patronas, N.T.3
  • 6
    • 0032943244 scopus 로고    scopus 로고
    • Hematoporphyrin derivative potentiate the radiosensitive effects of 2-DG in cancer cells
    • Dwarakanath BS, Adhikari JS, Jain V. Hematoporphyrin derivative potentiate the radiosensitive effects of 2-DG in cancer cells. Int J Radiat Oncol Biol Phys 1999;43:1125-33.
    • (1999) Int J Radiat Oncol Biol Phys , vol.43 , pp. 1125-1133
    • Dwarakanath, B.S.1    Adhikari, J.S.2    Jain, V.3
  • 7
    • 0026168635 scopus 로고
    • Effects of gamma-rays and glucose analogs on the energy metabolism of a cell line derived from human cerebral glioma
    • Dwarakanath BS, Jain V. Effects of gamma-rays and glucose analogs on the energy metabolism of a cell line derived from human cerebral glioma. Ind J Biochem Biophys 1991;28:203-9.
    • (1991) Ind J Biochem Biophys , vol.28 , pp. 203-209
    • Dwarakanath, B.S.1    Jain, V.2
  • 8
    • 0023277191 scopus 로고
    • Modification of the radiation-induced damage by 2-deoxy-D-glucose in organ cultures of human cerebral gliomas
    • Dwarakanath BS, Jain VK. Modification of the radiation-induced damage by 2-deoxy-D-glucose in organ cultures of human cerebral gliomas. Int J Radiat Oncol Biol Phys 1987;13:741-6.
    • (1987) Int J Radiat Oncol Biol Phys , vol.13 , pp. 741-746
    • Dwarakanath, B.S.1    Jain, V.K.2
  • 9
    • 0024418493 scopus 로고
    • Energy linked modifications of the radiation response in a human cerebral glioma cell line
    • Dwarakanath BS, Jain VK. Energy linked modifications of the radiation response in a human cerebral glioma cell line. Int J Radiat Oncol Biol Phys 1989;17:1033-40.
    • (1989) Int J Radiat Oncol Biol Phys , vol.17 , pp. 1033-1040
    • Dwarakanath, B.S.1    Jain, V.K.2
  • 11
    • 0032834447 scopus 로고    scopus 로고
    • Optimization of tumour radiotherapy: Part V. Radiosensitization by 2-deoxy-D-glucose and DNA ligand Hoechst-33342 in a murine tumour
    • Dwarakanath BS, Singh S, Jain V. Optimization of tumour radiotherapy: part V. Radiosensitization by 2-deoxy-D-glucose and DNA ligand Hoechst-33342 in a murine tumour. Ind J Exp Biol 1999;37:865-70.
    • (1999) Ind J Exp Biol , vol.37 , pp. 865-870
    • Dwarakanath, B.S.1    Singh, S.2    Jain, V.3
  • 12
    • 0035879414 scopus 로고    scopus 로고
    • Heterogeneity in 2-deoxy-D-glucose-induced modifications in energetics and radiation responses of human tumour cell lines
    • Dwarakanath BS, Zolzer F, Chandana S, et al. Heterogeneity in 2-deoxy-D-glucose-induced modifications in energetics and radiation responses of human tumour cell lines. Int J Radiat Oncol Biol Phys 2001;50:1051-61.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , pp. 1051-1061
    • Dwarakanath, B.S.1    Zolzer, F.2    Chandana, S.3
  • 13
    • 0026546960 scopus 로고
    • 2-Deoxy-D-glucose inhibits rejoining of radiation-induced DNA double-strand breaks in yeast
    • Frankenberg-Schwager M, Harbich R, Frankenberg D, et al. 2-deoxy-D-glucose inhibits rejoining of radiation-induced DNA double-strand breaks in yeast. Int J Radiat Biol 1992;61:185-90.
    • (1992) Int J Radiat Biol , vol.61 , pp. 185-190
    • Frankenberg-Schwager, M.1    Harbich, R.2    Frankenberg, D.3
  • 14
    • 0027484044 scopus 로고
    • Postoperative hypofractionated radiotherapy versus conventionally fractionated radiotherapy in malignant gliomas. A preliminary report on a randomized trial
    • Glinski B. Postoperative hypofractionated radiotherapy versus conventionally fractionated radiotherapy in malignant gliomas. A preliminary report on a randomized trial. J Neurooncol 1993;16:167-72.
    • (1993) J Neurooncol , vol.16 , pp. 167-172
    • Glinski, B.1
  • 15
    • 0041823221 scopus 로고    scopus 로고
    • Radiotherapy in supratentorial gliomas. A study of 821 cases
    • Heesters M, Molenaar W, Go GK. Radiotherapy in supratentorial gliomas. A study of 821 cases. Strahlenther Onkol 2003;179:606-14.
    • (2003) Strahlenther Onkol , vol.179 , pp. 606-614
    • Heesters, M.1    Molenaar, W.2    Go, G.K.3
  • 16
    • 0023682108 scopus 로고
    • Growth factors rapidly induce expression of the glucose transporter gene
    • Hiraki Y, Rosen OM, Birnbaum MJ. Growth factors rapidly induce expression of the glucose transporter gene. J Biol Chem 1988;263:13655-62.
    • (1988) J Biol Chem , vol.263 , pp. 13655-13662
    • Hiraki, Y.1    Rosen, O.M.2    Birnbaum, M.J.3
  • 17
    • 0015855708 scopus 로고
    • Enzymatic and cerebral metabolic effects of 2-deoxy-D-glucose
    • Horton RW, Meldrum BS, Bachelard HS. Enzymatic and cerebral metabolic effects of 2-deoxy-D-glucose. J Neurochem 1973;21:507-20.
    • (1973) J Neurochem , vol.21 , pp. 507-520
    • Horton, R.W.1    Meldrum, B.S.2    Bachelard, H.S.3
  • 19
    • 0020423724 scopus 로고
    • Energetics of cellular repair processes in a respiratory-deficient mutant of yeast
    • Jain VK, Gupta I, Lata K. Energetics of cellular repair processes in a respiratory-deficient mutant of yeast. Radiat Res 1982;92:463-73.
    • (1982) Radiat Res , vol.92 , pp. 463-473
    • Jain, V.K.1    Gupta, I.2    Lata, K.3
  • 20
    • 0018601843 scopus 로고
    • Optimization of cancer therapy: Part III. Effects of combining 2-deoxy-D-glucose treatment with gamma irradiation on normal mice
    • Jain VK, Kalia VK, Gopinath PM, et al. Optimization of cancer therapy: part III. Effects of combining 2-deoxy-D-glucose treatment with gamma irradiation on normal mice. Ind J Exp Biol 1979;17:1320-5.
    • (1979) Ind J Exp Biol , vol.17 , pp. 1320-1325
    • Jain, V.K.1    Kalia, V.K.2    Gopinath, P.M.3
  • 21
    • 0021993763 scopus 로고
    • Effects of 2-deoxy-D-glucose on glycolysis, proliferation kinetics and radiation response of human cancer cells
    • Jain VK, Kalia VK, Sharma R, et al. Effects of 2-deoxy-D-glucose on glycolysis, proliferation kinetics and radiation response of human cancer cells. Int J Radiat Oncol Biol Phys 1985;11:943-50.
    • (1985) Int J Radiat Oncol Biol Phys , vol.11 , pp. 943-950
    • Jain, V.K.1    Kalia, V.K.2    Sharma, R.3
  • 22
    • 0015867688 scopus 로고
    • Influence of energy metabolism on the repair of X-ray damage in living cells. III. Effects of 2-deoxy-D-glucose on liquid holding reactivation in yeast
    • Jain V, Pohlit W, Purohit SC. Influence of energy metabolism on the repair of X-ray damage in living cells. III. Effects of 2-deoxy-D-glucose on liquid holding reactivation in yeast. Biophysik 1973;10:137-42.
    • (1973) Biophysik , vol.10 , pp. 137-142
    • Jain, V.1    Pohlit, W.2    Purohit, S.C.3
  • 23
    • 0017586939 scopus 로고
    • Optimization of cancer therapy. Part II. Effects of combining 2-deoxy-D-glucose treatment with gamma irradiation on sarcoma-180
    • Jain VK, Porschen E, Feinendegen LE. Optimization of cancer therapy. Part II. Effects of combining 2-deoxy-D-glucose treatment with gamma irradiation on sarcoma-180. Ind J Exp Biol 1977;15:714-8.
    • (1977) Ind J Exp Biol , vol.15 , pp. 714-718
    • Jain, V.K.1    Porschen, E.2    Feinendegen, L.E.3
  • 24
    • 0026670040 scopus 로고
    • Effect of 2-deoxy-D-glucose on DNA double strand break repair, cell survival and energy metabolism in euoxic Ehrlich ascites tumour cells
    • Jha B, Pohlit W. Effect of 2-deoxy-D-glucose on DNA double strand break repair, cell survival and energy metabolism in euoxic Ehrlich ascites tumour cells. Int J Radiat Biol 1992;62:409-15.
    • (1992) Int J Radiat Biol , vol.62 , pp. 409-415
    • Jha, B.1    Pohlit, W.2
  • 25
    • 0027476668 scopus 로고
    • Reversibility of inhibition of DNA double strand break repair by 2-deoxy-D-glucose in Ehrlich ascites tumour cells
    • Jha B, Pohlit W. Reversibility of inhibition of DNA double strand break repair by 2-deoxy-D-glucose in Ehrlich ascites tumour cells. Int J Radiat Biol 1993;63:459-67.
    • (1993) Int J Radiat Biol , vol.63 , pp. 459-467
    • Jha, B.1    Pohlit, W.2
  • 26
    • 0020314762 scopus 로고
    • Optimization of cancer therapy. Part IV. Effects of 2-deoxy-D-glucose on radiation-induced chromosomal damage in PHA-stimulated peripheral leukocytes
    • Kalia VK, Jain VK, Otto FJ. Optimization of cancer therapy. Part IV. Effects of 2-deoxy-D-glucose on radiation-induced chromosomal damage in PHA-stimulated peripheral leukocytes. Ind J Exp Biol 1982;20:884-8.
    • (1982) Ind J Exp Biol , vol.20 , pp. 884-888
    • Kalia, V.K.1    Jain, V.K.2    Otto, F.J.3
  • 27
    • 0023639297 scopus 로고
    • Inhibition of rat fibrosarcoma growth by 2-DG
    • Kern KA, Norton JA. Inhibition of rat fibrosarcoma growth by 2-DG. Surgery 1987;102:380-5.
    • (1987) Surgery , vol.102 , pp. 380-385
    • Kern, K.A.1    Norton, J.A.2
  • 28
    • 0020546010 scopus 로고
    • Metabolic and hormonal responses of children and adolescents to fasting and 2-DG
    • Kerr DS, Hansen IL, Levy MM. Metabolic and hormonal responses of children and adolescents to fasting and 2-DG. Metabolism 1983;32:951-9.
    • (1983) Metabolism , vol.32 , pp. 951-959
    • Kerr, D.S.1    Hansen, I.L.2    Levy, M.M.3
  • 29
    • 0036867668 scopus 로고    scopus 로고
    • Importance of hypoxia in the biology and treatment of brain tumour
    • Knisely JP, Rockwell F. Importance of hypoxia in the biology and treatment of brain tumour. Neuroimaging Clin N Am 2002;12:525-36.
    • (2002) Neuroimaging Clin N Am , vol.12 , pp. 525-536
    • Knisely, J.P.1    Rockwell, F.2
  • 30
    • 0037394941 scopus 로고    scopus 로고
    • Radiochemotherapy of malignant glioma in adults. Clinical experiences
    • Kortmann RD, Jeremic B, Weller M, et al. Radiochemotherapy of malignant glioma in adults. Clinical experiences. Strahlenther Onkol 2003;179:219-32.
    • (2003) Strahlenther Onkol , vol.179 , pp. 219-232
    • Kortmann, R.D.1    Jeremic, B.2    Weller, M.3
  • 31
    • 4444336148 scopus 로고    scopus 로고
    • Immediate postoperative radiotherapy or "watch and wait" in the management of adult low-grade glioma?
    • Kortmann RD, Jeremic B, Weller M, et al. Immediate postoperative radiotherapy or "watch and wait" in the management of adult low-grade glioma? Strahlenther Onkol 2004;180:408-18.
    • (2004) Strahlenther Onkol , vol.180 , pp. 408-418
    • Kortmann, R.D.1    Jeremic, B.2    Weller, M.3
  • 32
    • 0001422847 scopus 로고
    • Certain metabolic and pharmacologic effects in cancer patients given infusions of 2-deoxy-D-glucose
    • Landau BR, Laszlo J, Stengle J, et al. Certain metabolic and pharmacologic effects in cancer patients given infusions of 2-deoxy-D-glucose. J Natl Cancer Inst 1958;21:485-94.
    • (1958) J Natl Cancer Inst , vol.21 , pp. 485-494
    • Landau, B.R.1    Laszlo, J.2    Stengle, J.3
  • 33
    • 0442284138 scopus 로고
    • The effect of 2-DG infusions on lipid and carbohydrate metabolism in man
    • Laszalo J, Harlan WR, Klein RF, et al. The effect of 2-DG infusions on lipid and carbohydrate metabolism in man. J Clin Invest 1960;40:171-6.
    • (1960) J Clin Invest , vol.40 , pp. 171-176
    • Laszalo, J.1    Harlan, W.R.2    Klein, R.F.3
  • 34
    • 0027324014 scopus 로고
    • Tumour response to ionising radiation and combined 2-deoxy-D-glucose application in Ehrlich ascites tumour bearing mice: Monitoring of tumour size and microscopic observations
    • Latz D, Thonke A, Juling-Pohlit L, et al. Tumour response to ionising radiation and combined 2-deoxy-D-glucose application in Ehrlich ascites tumour bearing mice: monitoring of tumour size and microscopic observations. Strahlentherapie 1993;169:405-11.
    • (1993) Strahlentherapie , vol.169 , pp. 405-411
    • Latz, D.1    Thonke, A.2    Juling-Pohlit, L.3
  • 35
    • 0029281350 scopus 로고
    • LENT SOMA tables
    • LENT SOMA tables. Radiother Oncol 1995;35:17-60.
    • (1995) Radiother Oncol , vol.35 , pp. 17-60
  • 36
    • 0037242253 scopus 로고    scopus 로고
    • Multivariate analysis of prognostic factors in patients with glioblastoma
    • Lutterbach J, Sauerbrei W, Guttenberger R. Multivariate analysis of prognostic factors in patients with glioblastoma. Strahlenther Onkol 2003;179:8-15.
    • (2003) Strahlenther Onkol , vol.179 , pp. 8-15
    • Lutterbach, J.1    Sauerbrei, W.2    Guttenberger, R.3
  • 37
    • 0037838840 scopus 로고    scopus 로고
    • Hypofractionated radiotherapy for poor prognosis malignant glioma: Matched pair survival analysis with MRC controls
    • McAleese JJ, Stenning SP, Ashley D, et al. Hypofractionated radiotherapy for poor prognosis malignant glioma: matched pair survival analysis with MRC controls. Radiother Oncol 2003;67:177-82.
    • (2003) Radiother Oncol , vol.67 , pp. 177-182
    • McAleese, J.J.1    Stenning, S.P.2    Ashley, D.3
  • 38
    • 15344340524 scopus 로고
    • Metabolism of ascites tumour cells III effects of 2-deoxy-D-glucose phosphorylation on phosphorous metabolism
    • McComb RB, Yushok WD. Metabolism of ascites tumour cells III effects of 2-deoxy-D-glucose phosphorylation on phosphorous metabolism. Cancer Res 1964;24:193-7.
    • (1964) Cancer Res , vol.24 , pp. 193-197
    • McComb, R.B.1    Yushok, W.D.2
  • 39
    • 0027772521 scopus 로고
    • Growth factors, mitogens, oncogenes and the regulation of glucose transport
    • Merall NW, Plevin R, Gould GW. Growth factors, mitogens, oncogenes and the regulation of glucose transport. Cell Signal 1993;5:667-75.
    • (1993) Cell Signal , vol.5 , pp. 667-675
    • Merall, N.W.1    Plevin, R.2    Gould, G.W.3
  • 40
    • 0030009250 scopus 로고    scopus 로고
    • Improving cancer radiotherapy with 2-deoxy-D-glucose: Phase I/II clinical trial on human cerebral glioma
    • Mohanti BK, Rath GK, Anantha N, et al. Improving cancer radiotherapy with 2-deoxy-D-glucose: phase I/II clinical trial on human cerebral glioma. Int J Radiat Oncol Biol Phys 1996;35:103-11.
    • (1996) Int J Radiat Oncol Biol Phys , vol.35 , pp. 103-111
    • Mohanti, B.K.1    Rath, G.K.2    Anantha, N.3
  • 41
    • 3042855912 scopus 로고    scopus 로고
    • Radiotherapy for high-grade gliomas. Does altered fractionation improve the outcome?
    • Nieder C, Andratschke N, Widenmann N, et al. Radiotherapy for high-grade gliomas. Does altered fractionation improve the outcome? Strahlenther Onkol 2004;180:401-7.
    • (2004) Strahlenther Onkol , vol.180 , pp. 401-407
    • Nieder, C.1    Andratschke, N.2    Widenmann, N.3
  • 42
    • 0141794250 scopus 로고    scopus 로고
    • Prediction of pathology and survival by FDG PET in gliomas
    • Padma MV, Said S, Jacobs M, et al. Prediction of pathology and survival by FDG PET in gliomas. J Neurooncol 2003;64:227-37.
    • (2003) J Neurooncol , vol.64 , pp. 227-237
    • Padma, M.V.1    Said, S.2    Jacobs, M.3
  • 43
    • 0019948401 scopus 로고
    • Experimental evaluation of the glucose antimetabolite, 2-deoxy-D-glucose (2-DG), as a possible adjuvant to radiotherapy of tumours. I. Kinetics of growth and survival of Ehrlich ascites tumour cells (EATC) in vitro and growth of solid tumours after 2-DG and X-irradiation
    • Purohit SC, Pohlit W. Experimental evaluation of the glucose antimetabolite, 2-deoxy-D-glucose (2-DG), as a possible adjuvant to radiotherapy of tumours. I. Kinetics of growth and survival of Ehrlich ascites tumour cells (EATC) in vitro and growth of solid tumours after 2-DG and X-irradiation. Int J Radiat Oncology Biol Phys 1982;8:495-9.
    • (1982) Int J Radiat Oncology Biol Phys , vol.8 , pp. 495-499
    • Purohit, S.C.1    Pohlit, W.2
  • 44
    • 0018628457 scopus 로고
    • High dose radiation therapy in the treatment of malignant gliomas: Final report
    • Salazar OM, Rubin P, Feldstein ML, et al. High dose radiation therapy in the treatment of malignant gliomas: final report. Int J Radiat Oncol Biol Phys 1979;5:1733-40.
    • (1979) Int J Radiat Oncol Biol Phys , vol.5 , pp. 1733-1740
    • Salazar, O.M.1    Rubin, P.2    Feldstein, M.L.3
  • 45
    • 0030921103 scopus 로고    scopus 로고
    • c-Myc transactivation of LDH-A: Implication for tumour metabolism and growth
    • Shim H, Dolde C, Lewis BC, et al. c-Myc transactivation of LDH-A: implication for tumour metabolism and growth. Proc Natl Acad Sci USA 1997;94:6658-63.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6658-6663
    • Shim, H.1    Dolde, C.2    Lewis, B.C.3
  • 47
    • 0025065024 scopus 로고
    • Effects of 5-bromo-deoxy-uridine and 2-deoxy-D-glucose on radiation-induced micronuclei in mouse bone marrow
    • Singh SP, Singh S, Jain V. Effects of 5-bromo-deoxy-uridine and 2-deoxy-D-glucose on radiation-induced micronuclei in mouse bone marrow. Int J Radiat Biol 1990;58:791-7.
    • (1990) Int J Radiat Biol , vol.58 , pp. 791-797
    • Singh, S.P.1    Singh, S.2    Jain, V.3
  • 48
    • 0024452804 scopus 로고
    • Design and analysis of phase I clinical trials
    • Storer BE. Design and analysis of phase I clinical trials. Biometrics 1989;45:925-37.
    • (1989) Biometrics , vol.45 , pp. 925-937
    • Storer, B.E.1
  • 49
    • 0024395712 scopus 로고
    • Clinical interest determinations of cellular radiosensitivity
    • Suit HD, Baumann M, Skates S, et al. Clinical interest determinations of cellular radiosensitivity. Int J Radiat Biol 1989;56:725-37.
    • (1989) Int J Radiat Biol , vol.56 , pp. 725-737
    • Suit, H.D.1    Baumann, M.2    Skates, S.3
  • 50
    • 0032438507 scopus 로고    scopus 로고
    • Brain tumour survival: Results from the National Cancer Data Base
    • Surawicz T, Davis F, Freels S, et al. Brain tumour survival: results from the National Cancer Data Base. J Neurooncol 1998;40:151-60.
    • (1998) J Neurooncol , vol.40 , pp. 151-160
    • Surawicz, T.1    Davis, F.2    Freels, S.3
  • 51
    • 23044487054 scopus 로고    scopus 로고
    • The glycolytic inhibitor 2-deoxy-D-glucose does not enhance radiation-induced apoptosis in mouse thymocytes and splenocytes in vitro
    • in press
    • Swamy RK, Manickam J, Adhikari JS, et al. The glycolytic inhibitor 2-deoxy-D-glucose does not enhance radiation-induced apoptosis in mouse thymocytes and splenocytes in vitro. Ind J Exp Biol 2005:43(in press).
    • (2005) Ind J Exp Biol , vol.43
    • Swamy, R.K.1    Manickam, J.2    Adhikari, J.S.3
  • 52
    • 0019065462 scopus 로고
    • Thermoregulatory and related responses to 2-deoxy-D-glucose administration in humans
    • Thompson DA, Lilavivathana U, Campbell RG, et al. Thermoregulatory and related responses to 2-deoxy-D-glucose administration in humans. Am J Physiol 1980;239:R-291-5.
    • (1980) Am J Physiol , vol.239
    • Thompson, D.A.1    Lilavivathana, U.2    Campbell, R.G.3
  • 54
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science 1956;123:309-14.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 55
    • 0017580461 scopus 로고
    • Enzymology of cancer cells
    • Weber G. Enzymology of cancer cells. N Engl J Med 1977;296:541-51.
    • (1977) N Engl J Med , vol.296 , pp. 541-551
    • Weber, G.1
  • 56
    • 0015409718 scopus 로고
    • Glycolysis, respiration, and anomalous gene expression in experimental hepatomas
    • Weinhouse S. Glycolysis, respiration, and anomalous gene expression in experimental hepatomas. Cancer Res 1972;32:2007-16.
    • (1972) Cancer Res , vol.32 , pp. 2007-2016
    • Weinhouse, S.1
  • 57
    • 77049176768 scopus 로고
    • The effect of 2-deoxy-D-glucose on glycolysis and respiration of tumour and normal tissues
    • Woodward GE, Hudson MT. The effect of 2-deoxy-D-glucose on glycolysis and respiration of tumour and normal tissues. Cancer Res 1954;14:599-605.
    • (1954) Cancer Res , vol.14 , pp. 599-605
    • Woodward, G.E.1    Hudson, M.T.2
  • 58
    • 0025099995 scopus 로고
    • Radiosensitivity, recovery and dose rate effect in three human glioma cell lines
    • Yang X, Darling J, McMillan T, et al. Radiosensitivity, recovery and dose rate effect in three human glioma cell lines. Radiother Oncol 1990;19:49-56.
    • (1990) Radiother Oncol , vol.19 , pp. 49-56
    • Yang, X.1    Darling, J.2    McMillan, T.3
  • 59
    • 0030023026 scopus 로고    scopus 로고
    • Wide expression of the human erythrocyte glucose transporter Glut1 in human cancers
    • Younes M, Lechago LV, Somoano JR, et al. Wide expression of the human erythrocyte glucose transporter Glut1 in human cancers. Cancer Res 1996;56:1164-7.
    • (1996) Cancer Res , vol.56 , pp. 1164-1167
    • Younes, M.1    Lechago, L.V.2    Somoano, J.R.3
  • 60
    • 0018834143 scopus 로고
    • Principles of the new World Health Organization (WHO) classification of brain tumours
    • Zulch KJ. Principles of the new World Health Organization (WHO) classification of brain tumours. Neuroradiology 1980;19:59-70.
    • (1980) Neuroradiology , vol.19 , pp. 59-70
    • Zulch, K.J.1


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