Pitolisant, an inverse agonist of the histamine H3 receptor: An alternative stimulant for narcolepsy-cataplexy in teenagers with refractory sleepiness

Clinical Neuropharmacology

Volumn 35, Issue 2, 2012, Pages 55-60

  Inocente, Clara ^a,b   Arnulf, Isabelle ^c,d   Bastuji, Hélène ^a   Thibault Stoll, Anne ^e   Raoux, Aude ^a,d   Reimão, Rubens ^b   Lin, Jian Sheng ^a   Franco, Patricia ^a,d  

^a UNIVERSITÉ LYON 1   (France)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d National Reference Centre for Orphan Diseases   (France)

^e Clinique Sainte BARBE   (France)

Author keywords

children; histamine; narcolepsy; sleep disorders; wakefulness

Indexed keywords

CLOMIPRAMINE; DEXAMPHETAMINE; ESCITALOPRAM; HISTAMINE H3 RECEPTOR; MAZINDOL; METHYLPHENIDATE; MODAFINIL; OXYBATE SODIUM; PITOLISANT; VENLAFAXINE; VERAPAMIL;

ADOLESCENT; ARTICLE; CASE REPORT; CATALEPSY; CATAPLEXY; CHILD; DISEASE COURSE; DISEASE SEVERITY; DIZZINESS; DRUG ACTIVITY; DRUG DOSE INCREASE; DRUG TARGETING; DRUG WITHDRAWAL; FEMALE; FLUSHING; HALLUCINATION; HEADACHE; HEART PALPITATION; HEART VENTRICLE EXTRASYSTOLE; HOT FLUSH; HUMAN; INSOMNIA; IRRITABILITY; LEG PAIN; MALE; MORNING DOSAGE; NARCOLEPSY; NAUSEA; OFF LABEL DRUG USE; PRIORITY JOURNAL; RESPIRATION DEPRESSION; RISK BENEFIT ANALYSIS; SCHOOL CHILD; SIDE EFFECT; SOMNOLENCE; TACHYCARDIA; URINE RETENTION; WAKEFULNESS; WEIGHT GAIN;

ADOLESCENT; CATAPLEXY; CENTRAL NERVOUS SYSTEM STIMULANTS; DRUG INVERSE AGONISM; FEMALE; FOLLOW-UP STUDIES; HISTAMINE AGONISTS; HUMANS; MALE; NARCOLEPSY; OFF-LABEL USE; PIPERIDINES; RECEPTORS, HISTAMINE H3; SLEEP STAGES;

EID: 84862791691     PISSN: 03625664     EISSN: 1537162X     Source Type: Journal    
DOI: 10.1097/WNF.0b013e318246879d     Document Type: Article

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