-
1
-
-
0027595948
-
Tissue engineering
-
Langer R., Vacanti J.P. Tissue engineering. Science 1993, 260:920-926.
-
(1993)
Science
, vol.260
, pp. 920-926
-
-
Langer, R.1
Vacanti, J.P.2
-
2
-
-
1842484779
-
Designing materials for biology and medicine
-
Langer R., Tirrell D.A. Designing materials for biology and medicine. Nature 2004, 428:487-492.
-
(2004)
Nature
, vol.428
, pp. 487-492
-
-
Langer, R.1
Tirrell, D.A.2
-
3
-
-
84877018587
-
How smart do biomaterials need to be? A translational science and clinical point of view
-
Holzapfel B.M., Reichert J.C., Schantz J.T., Gbureck U., Rackwitz L., Noth U., Jakob F., Rudert M., Groll J., Hutmacher D.W. How smart do biomaterials need to be? A translational science and clinical point of view. Adv. Drug Deliv. Rev. 2013, 65:581-603.
-
(2013)
Adv. Drug Deliv. Rev.
, vol.65
, pp. 581-603
-
-
Holzapfel, B.M.1
Reichert, J.C.2
Schantz, J.T.3
Gbureck, U.4
Rackwitz, L.5
Noth, U.6
Jakob, F.7
Rudert, M.8
Groll, J.9
Hutmacher, D.W.10
-
4
-
-
84881112672
-
The evolution of the cancer niche during multistage carcinogenesis
-
Barcellos-Hoff M.H., Lyden D., Wang T.C. The evolution of the cancer niche during multistage carcinogenesis. Nat. Rev. Cancer 2013, 13:511-518.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 511-518
-
-
Barcellos-Hoff, M.H.1
Lyden, D.2
Wang, T.C.3
-
5
-
-
0035005758
-
Seed and soil revisited: contribution of the organ microenvironment to cancer metastasis
-
(vii-viiii)
-
Fidler I.J. Seed and soil revisited: contribution of the organ microenvironment to cancer metastasis. Surg. Oncol. Clin. N. Am. 2001, 10:257-269. (vii-viiii).
-
(2001)
Surg. Oncol. Clin. N. Am.
, vol.10
, pp. 257-269
-
-
Fidler, I.J.1
-
6
-
-
50549121134
-
The distribution of secondary growths in cancer of the breast
-
Paget S. The distribution of secondary growths in cancer of the breast. Lancet 1889, 1:571-573.
-
(1889)
Lancet
, vol.1
, pp. 571-573
-
-
Paget, S.1
-
7
-
-
1942422761
-
Update on NCI in vitro drug screen utilities
-
Holbeck S.L. Update on NCI in vitro drug screen utilities. Eur. J. Cancer 2004, 40:785-793.
-
(2004)
Eur. J. Cancer
, vol.40
, pp. 785-793
-
-
Holbeck, S.L.1
-
8
-
-
75749158184
-
Biomaterials offer cancer research the third dimension
-
Hutmacher D.W. Biomaterials offer cancer research the third dimension. Nat. Mater. 2010, 9:90-93.
-
(2010)
Nat. Mater.
, vol.9
, pp. 90-93
-
-
Hutmacher, D.W.1
-
9
-
-
0042358985
-
Cell culture: biology's new dimension
-
Abbott A. Cell culture: biology's new dimension. Nature 2003, 424:870-872.
-
(2003)
Nature
, vol.424
, pp. 870-872
-
-
Abbott, A.1
-
10
-
-
77953066865
-
The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures
-
Krause S., Maffini M.V., Soto A.M., Sonnenschein C. The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures. BMC Cancer 2010, 10:263.
-
(2010)
BMC Cancer
, vol.10
, pp. 263
-
-
Krause, S.1
Maffini, M.V.2
Soto, A.M.3
Sonnenschein, C.4
-
11
-
-
77955692939
-
Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts
-
Olsen C.J., Moreira J., Lukanidin E.M., Ambartsumian N.S. Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts. BMC Cancer 2010, 10:444.
-
(2010)
BMC Cancer
, vol.10
, pp. 444
-
-
Olsen, C.J.1
Moreira, J.2
Lukanidin, E.M.3
Ambartsumian, N.S.4
-
12
-
-
84876077149
-
A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer
-
Clark A.K., Taubenberger A.V., Taylor R.A., Niranjan B., Chea Z.Y., Zotenko E., Sieh S., Pedersen J.S., Norden S., Frydenberg M., Grummet J.P., Pook D.W., Stirzaker C., Clark S.J., Lawrence M.G., Ellem S.J., Hutmacher D.W., Risbridger G.P. A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer. Biomaterials 2013, 34:4777-4785.
-
(2013)
Biomaterials
, vol.34
, pp. 4777-4785
-
-
Clark, A.K.1
Taubenberger, A.V.2
Taylor, R.A.3
Niranjan, B.4
Chea, Z.Y.5
Zotenko, E.6
Sieh, S.7
Pedersen, J.S.8
Norden, S.9
Frydenberg, M.10
Grummet, J.P.11
Pook, D.W.12
Stirzaker, C.13
Clark, S.J.14
Lawrence, M.G.15
Ellem, S.J.16
Hutmacher, D.W.17
Risbridger, G.P.18
-
13
-
-
77952300112
-
Can tissue engineering concepts advance tumor biology research?
-
Hutmacher D.W., Loessner D., Rizzi S., Kaplan D.L., Mooney D.J., Clements J.A. Can tissue engineering concepts advance tumor biology research?. Trends Biotechnol. 2010, 28:125-133.
-
(2010)
Trends Biotechnol.
, vol.28
, pp. 125-133
-
-
Hutmacher, D.W.1
Loessner, D.2
Rizzi, S.3
Kaplan, D.L.4
Mooney, D.J.5
Clements, J.A.6
-
14
-
-
70349329669
-
Translating tissue engineering technology platforms into cancer research
-
Hutmacher D.W., Horch R.E., Loessner D., Rizzi S., Sieh S., Reichert J.C., Clements J.A., Beier J.P., Arkudas A., Bleiziffer O., Kneser U. Translating tissue engineering technology platforms into cancer research. J. Cell. Mol. Med. 2009, 13:1417-1427.
-
(2009)
J. Cell. Mol. Med.
, vol.13
, pp. 1417-1427
-
-
Hutmacher, D.W.1
Horch, R.E.2
Loessner, D.3
Rizzi, S.4
Sieh, S.5
Reichert, J.C.6
Clements, J.A.7
Beier, J.P.8
Arkudas, A.9
Bleiziffer, O.10
Kneser, U.11
-
15
-
-
77956187576
-
Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells
-
Loessner D., Stok K.S., Lutolf M.P., Hutmacher D.W., Clements J.A., Rizzi S.C. Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells. Biomaterials 2010, 31:8494-8506.
-
(2010)
Biomaterials
, vol.31
, pp. 8494-8506
-
-
Loessner, D.1
Stok, K.S.2
Lutolf, M.P.3
Hutmacher, D.W.4
Clements, J.A.5
Rizzi, S.C.6
-
16
-
-
84880507847
-
A bioengineered 3D ovarian cancer model for the assessment of peptidase-mediated enhancement of spheroid growth and intraperitoneal spread
-
Loessner D., Rizzi S.C., Stok K.S., Fuehrmann T., Hollier B., Magdolen V., Hutmacher D.W., Clements J.A. A bioengineered 3D ovarian cancer model for the assessment of peptidase-mediated enhancement of spheroid growth and intraperitoneal spread. Biomaterials 2013, 34:7389-7400.
-
(2013)
Biomaterials
, vol.34
, pp. 7389-7400
-
-
Loessner, D.1
Rizzi, S.C.2
Stok, K.S.3
Fuehrmann, T.4
Hollier, B.5
Magdolen, V.6
Hutmacher, D.W.7
Clements, J.A.8
-
17
-
-
84919650138
-
Hydrogel microwell arrays allow the assessment of protease-associated enhancement of cancer cell aggregation and survival
-
Loessner D., Kobel S., Clements J.A., Lutolf M.P., Hutmacher D.W. Hydrogel microwell arrays allow the assessment of protease-associated enhancement of cancer cell aggregation and survival. Microarrays 2013, 2:208-227.
-
(2013)
Microarrays
, vol.2
, pp. 208-227
-
-
Loessner, D.1
Kobel, S.2
Clements, J.A.3
Lutolf, M.P.4
Hutmacher, D.W.5
-
18
-
-
84899623868
-
Gelatine methacrylamide-based hydrogels: an alternative three-dimensional cancer cell culture system
-
Kaemmerer E., Melchels F.P., Holzapfel B.M., Meckel T., Hutmacher D.W., Loessner D. Gelatine methacrylamide-based hydrogels: an alternative three-dimensional cancer cell culture system. Acta Biomater. 2014, 10:2551-2562.
-
(2014)
Acta Biomater.
, vol.10
, pp. 2551-2562
-
-
Kaemmerer, E.1
Melchels, F.P.2
Holzapfel, B.M.3
Meckel, T.4
Hutmacher, D.W.5
Loessner, D.6
-
19
-
-
77956412826
-
Interactions between human osteoblasts and prostate cancer cells in a novel 3D in vitro model
-
Sieh S., Lubik A.A., Clements J.A., Nelson C.C., Hutmacher D.W. Interactions between human osteoblasts and prostate cancer cells in a novel 3D in vitro model. Organogenesis 2010, 6:181-188.
-
(2010)
Organogenesis
, vol.6
, pp. 181-188
-
-
Sieh, S.1
Lubik, A.A.2
Clements, J.A.3
Nelson, C.C.4
Hutmacher, D.W.5
-
20
-
-
84866039025
-
Phenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironment
-
Sieh S., Taubenberger A.V., Rizzi S.C., Sadowski M., Lehman M.L., Rockstroh A., An J., Clements J.A., Nelson C.C., Hutmacher D.W. Phenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironment. PLoS One 2012, 7:e40217.
-
(2012)
PLoS One
, vol.7
, pp. e40217
-
-
Sieh, S.1
Taubenberger, A.V.2
Rizzi, S.C.3
Sadowski, M.4
Lehman, M.L.5
Rockstroh, A.6
An, J.7
Clements, J.A.8
Nelson, C.C.9
Hutmacher, D.W.10
-
21
-
-
84878114431
-
Humanised xenograft models of bone metastasis revisited: novel insights into species-specific mechanisms of cancer cell osteotropism
-
Holzapfel B.M., Thibaudeau L., Hesami P., Taubenberger A., Holzapfel N.P., Mayer-Wagner S., Power C., Clements J., Russell P., Hutmacher D.W. Humanised xenograft models of bone metastasis revisited: novel insights into species-specific mechanisms of cancer cell osteotropism. Cancer Metastasis Rev. 2013, 32:129-145.
-
(2013)
Cancer Metastasis Rev.
, vol.32
, pp. 129-145
-
-
Holzapfel, B.M.1
Thibaudeau, L.2
Hesami, P.3
Taubenberger, A.4
Holzapfel, N.P.5
Mayer-Wagner, S.6
Power, C.7
Clements, J.8
Russell, P.9
Hutmacher, D.W.10
-
22
-
-
84897037502
-
Paracrine interactions between LNCaP prostate cancer cells and bioengineered bone in 3D in vitro culture reflect molecular changes during bone metastasis
-
Sieh S., Taubenberger A.V., Lehman M.L., Clements J.A., Nelson C.C., Hutmacher D.W. Paracrine interactions between LNCaP prostate cancer cells and bioengineered bone in 3D in vitro culture reflect molecular changes during bone metastasis. Bone 2014, 63:121-131.
-
(2014)
Bone
, vol.63
, pp. 121-131
-
-
Sieh, S.1
Taubenberger, A.V.2
Lehman, M.L.3
Clements, J.A.4
Nelson, C.C.5
Hutmacher, D.W.6
-
23
-
-
84898600942
-
A humanized tissue-engineered in vivo model to dissect interactions between human prostate cancer cells and human bone
-
Hesami P., Holzapfel B.M., Taubenberger A., Roudier M., Fazli L., Sieh S., Thibaudeau L., Gregory L.S., Hutmacher D.W., Clements J.A. A humanized tissue-engineered in vivo model to dissect interactions between human prostate cancer cells and human bone. Clin. Exp. Metastasis 2014, 31(4):435-446.
-
(2014)
Clin. Exp. Metastasis
, vol.31
, Issue.4
, pp. 435-446
-
-
Hesami, P.1
Holzapfel, B.M.2
Taubenberger, A.3
Roudier, M.4
Fazli, L.5
Sieh, S.6
Thibaudeau, L.7
Gregory, L.S.8
Hutmacher, D.W.9
Clements, J.A.10
-
24
-
-
84896728350
-
Species-specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone
-
Holzapfel B.M., Wagner F., Loessner D., Holzapfel N.P., Thibaudeau L., Crawford R., Ling M.T., Clements J.A., Russell P.J., Hutmacher D.W. Species-specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone. Biomaterials 2014, 35:4108-4115.
-
(2014)
Biomaterials
, vol.35
, pp. 4108-4115
-
-
Holzapfel, B.M.1
Wagner, F.2
Loessner, D.3
Holzapfel, N.P.4
Thibaudeau, L.5
Crawford, R.6
Ling, M.T.7
Clements, J.A.8
Russell, P.J.9
Hutmacher, D.W.10
-
25
-
-
84892805731
-
Cancer statistics, 2014
-
Siegel R., Ma J., Zou Z., Jemal A. Cancer statistics, 2014. CA Cancer J. Clin. 2014, 64:9-29.
-
(2014)
CA Cancer J. Clin.
, vol.64
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
26
-
-
84875421047
-
Prostate cancer: is it time to expand the research focus to early-life exposures?
-
Sutcliffe S., Colditz G.A. Prostate cancer: is it time to expand the research focus to early-life exposures?. Nat. Rev. Cancer 2013, 13:208-518.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 208-518
-
-
Sutcliffe, S.1
Colditz, G.A.2
-
27
-
-
60749137451
-
Beyond chemotherapy: targeted therapies in ovarian cancer
-
Yap T.A., Carden C.P., Kaye S.B. Beyond chemotherapy: targeted therapies in ovarian cancer. Nat. Rev. Cancer 2009, 9:167-181.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 167-181
-
-
Yap, T.A.1
Carden, C.P.2
Kaye, S.B.3
-
28
-
-
77649186477
-
Breast and prostate cancer: more similar than different
-
Risbridger G.P., Davis I.D., Birrell S.N., Tilley W.D. Breast and prostate cancer: more similar than different. Nat. Rev. Cancer 2010, 10:205-212.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 205-212
-
-
Risbridger, G.P.1
Davis, I.D.2
Birrell, S.N.3
Tilley, W.D.4
-
29
-
-
80053157914
-
Unravelling the complexity of metastasis - molecular understanding and targeted therapies
-
Sethi N., Kang Y. Unravelling the complexity of metastasis - molecular understanding and targeted therapies. Nat. Rev. Cancer 2011, 11:735-748.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 735-748
-
-
Sethi, N.1
Kang, Y.2
-
30
-
-
84884535896
-
Cancer drug resistance: an evolving paradigm
-
Holohan C., Van Schaeybroeck S., Longley D.B., Johnston P.G. Cancer drug resistance: an evolving paradigm. Nat. Rev. Cancer 2013, 13:714-726.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 714-726
-
-
Holohan, C.1
Van Schaeybroeck, S.2
Longley, D.B.3
Johnston, P.G.4
-
31
-
-
80053168788
-
Rethinking ovarian cancer: recommendations for improving outcomes
-
Vaughan S., Coward J.I., Bast R.C., Berchuck A., Berek J.S., Brenton J.D., Coukos G., Crum C.C., Drapkin R., Etemadmoghadam D., Friedlander M., Gabra H., Kaye S.B., Lord C.J., Lengyel E., Levine D.A., McNeish I.A., Menon U., Mills G.B., Nephew K.P., Oza A.M., Sood A.K., Stronach E.A., Walczak H., Bowtell D.D., Balkwill F.R. Rethinking ovarian cancer: recommendations for improving outcomes. Nat. Rev. Cancer 2011, 11:719-725.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 719-725
-
-
Vaughan, S.1
Coward, J.I.2
Bast, R.C.3
Berchuck, A.4
Berek, J.S.5
Brenton, J.D.6
Coukos, G.7
Crum, C.C.8
Drapkin, R.9
Etemadmoghadam, D.10
Friedlander, M.11
Gabra, H.12
Kaye, S.B.13
Lord, C.J.14
Lengyel, E.15
Levine, D.A.16
McNeish, I.A.17
Menon, U.18
Mills, G.B.19
Nephew, K.P.20
Oza, A.M.21
Sood, A.K.22
Stronach, E.A.23
Walczak, H.24
Bowtell, D.D.25
Balkwill, F.R.26
more..
-
32
-
-
77951784627
-
Ovarian cancer pathogenesis: a model in evolution
-
Karst A.M., Drapkin R. Ovarian cancer pathogenesis: a model in evolution. J. Oncol. 2010, 2010:932371.
-
(2010)
J. Oncol.
, vol.2010
, pp. 932371
-
-
Karst, A.M.1
Drapkin, R.2
-
33
-
-
84883257841
-
The origin of ovarian cancers-hypotheses and controversies
-
Auersperg N. The origin of ovarian cancers-hypotheses and controversies. Front. Biosci. 2013, 5:709-719.
-
(2013)
Front. Biosci.
, vol.5
, pp. 709-719
-
-
Auersperg, N.1
-
34
-
-
77956495728
-
Ovarian cancer development and metastasis
-
Lengyel E. Ovarian cancer development and metastasis. Am. J. Pathol. 2010, 177:1053-1064.
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 1053-1064
-
-
Lengyel, E.1
-
35
-
-
1542268288
-
Signature of a silent killer: expression profiling in epithelial ovarian cancer
-
Le Page C., Provencher D., Maugard C.M., Ouellet V., Mes-Masson A.M. Signature of a silent killer: expression profiling in epithelial ovarian cancer. Expert. Rev. Mol. Diagn. 2004, 4:157-167.
-
(2004)
Expert. Rev. Mol. Diagn.
, vol.4
, pp. 157-167
-
-
Le Page, C.1
Provencher, D.2
Maugard, C.M.3
Ouellet, V.4
Mes-Masson, A.M.5
-
36
-
-
67649440886
-
The biology of ovarian cancer: new opportunities for translation
-
Bast R.C., Hennessy B., Mills G.B. The biology of ovarian cancer: new opportunities for translation. Nat. Rev. Cancer 2009, 9:415-428.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 415-428
-
-
Bast, R.C.1
Hennessy, B.2
Mills, G.B.3
-
37
-
-
0043240182
-
Ovarian cancer: strategies for overcoming resistance to chemotherapy
-
Agarwal R., Kaye S.B. Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat. Rev. Cancer 2003, 3:502-516.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 502-516
-
-
Agarwal, R.1
Kaye, S.B.2
-
38
-
-
30044438368
-
Intraperitoneal cisplatin and paclitaxel in ovarian cancer
-
Armstrong D.K., Bundy B., Wenzel L., Huang H.Q., Baergen R., Lele S., Copeland L.J., Walker J.L., Burger R.A. Intraperitoneal cisplatin and paclitaxel in ovarian cancer. N. Engl. J. Med. 2006, 354:34-43.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 34-43
-
-
Armstrong, D.K.1
Bundy, B.2
Wenzel, L.3
Huang, H.Q.4
Baergen, R.5
Lele, S.6
Copeland, L.J.7
Walker, J.L.8
Burger, R.A.9
-
39
-
-
78149457486
-
Intraperitoneal therapy for peritoneal cancer
-
Lu Z., Wang J., Wientjes M.G., Au J.L. Intraperitoneal therapy for peritoneal cancer. Future Oncol. 2010, 6:1625-1641.
-
(2010)
Future Oncol.
, vol.6
, pp. 1625-1641
-
-
Lu, Z.1
Wang, J.2
Wientjes, M.G.3
Au, J.L.4
-
40
-
-
84880845489
-
Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study
-
Sieh W., Kobel M., Longacre T.A., Bowtell D.D., deFazio A., Goodman M.T., Hogdall E., Deen S., Wentzensen N., Moysich K.B., Brenton J.D., Clarke B.A., Menon U., Gilks C.B., Kim A., Madore J., Fereday S., George J., Galletta L., Lurie G., Wilkens L.R., Carney M.E., Thompson P.J., Matsuno R.K., Kjaer S.K., Jensen A., Hogdall C., Kalli K.R., Fridley B.L., Keeney G.L., Vierkant R.A., Cunningham J.M., Brinton L.A., Yang H.P., Sherman M.E., Garcia-Closas M., Lissowska J., Odunsi K., Morrison C., Lele S., Bshara W., Sucheston L., Jimenez-Linan M., Driver K., Alsop J., Mack M., McGuire V., Rothstein J.H., Rosen B.P., Bernardini M.Q., Mackay H., Oza A., Wozniak E.L., Benjamin E., Gentry-Maharaj A., Gayther S.A., Tinker A.V., Prentice L.M., Chow C., Anglesio M.S., Johnatty S.E., Chenevix-Trench G., Whittemore A.S., Pharoah P.D., Goode E.L., Huntsman D.G., Ramus S.J. Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study. Lancet Oncol. 2013, 14:853-862.
-
(2013)
Lancet Oncol.
, vol.14
, pp. 853-862
-
-
Sieh, W.1
Kobel, M.2
Longacre, T.A.3
Bowtell, D.D.4
deFazio, A.5
Goodman, M.T.6
Hogdall, E.7
Deen, S.8
Wentzensen, N.9
Moysich, K.B.10
Brenton, J.D.11
Clarke, B.A.12
Menon, U.13
Gilks, C.B.14
Kim, A.15
Madore, J.16
Fereday, S.17
George, J.18
Galletta, L.19
Lurie, G.20
Wilkens, L.R.21
Carney, M.E.22
Thompson, P.J.23
Matsuno, R.K.24
Kjaer, S.K.25
Jensen, A.26
Hogdall, C.27
Kalli, K.R.28
Fridley, B.L.29
Keeney, G.L.30
Vierkant, R.A.31
Cunningham, J.M.32
Brinton, L.A.33
Yang, H.P.34
Sherman, M.E.35
Garcia-Closas, M.36
Lissowska, J.37
Odunsi, K.38
Morrison, C.39
Lele, S.40
Bshara, W.41
Sucheston, L.42
Jimenez-Linan, M.43
Driver, K.44
Alsop, J.45
Mack, M.46
McGuire, V.47
Rothstein, J.H.48
Rosen, B.P.49
Bernardini, M.Q.50
Mackay, H.51
Oza, A.52
Wozniak, E.L.53
Benjamin, E.54
Gentry-Maharaj, A.55
Gayther, S.A.56
Tinker, A.V.57
Prentice, L.M.58
Chow, C.59
Anglesio, M.S.60
Johnatty, S.E.61
Chenevix-Trench, G.62
Whittemore, A.S.63
Pharoah, P.D.64
Goode, E.L.65
Huntsman, D.G.66
Ramus, S.J.67
more..
-
41
-
-
75949124984
-
Treatment strategies for high-risk locally advanced prostate cancer
-
Rosenthal S.A., Sandler H.M. Treatment strategies for high-risk locally advanced prostate cancer. Nat. Rev. Urol. 2010, 7:31-38.
-
(2010)
Nat. Rev. Urol.
, vol.7
, pp. 31-38
-
-
Rosenthal, S.A.1
Sandler, H.M.2
-
42
-
-
69449085747
-
Management of locally advanced prostate cancer
-
Payne H. Management of locally advanced prostate cancer. Asian J. Androl. 2009, 11:81-87.
-
(2009)
Asian J. Androl.
, vol.11
, pp. 81-87
-
-
Payne, H.1
-
43
-
-
0036112592
-
The current state of hormonal therapy for prostate cancer
-
Hellerstedt B.A., Pienta K.J. The current state of hormonal therapy for prostate cancer. CA Cancer J. Clin. 2002, 52:154-179.
-
(2002)
CA Cancer J. Clin.
, vol.52
, pp. 154-179
-
-
Hellerstedt, B.A.1
Pienta, K.J.2
-
44
-
-
0034085989
-
Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients
-
Bubendorf L., Schopfer A., Wagner U., Sauter G., Moch H., Willi N., Gasser T.C., Mihatsch M.J. Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum. Pathol. 2000, 31:578-583.
-
(2000)
Hum. Pathol.
, vol.31
, pp. 578-583
-
-
Bubendorf, L.1
Schopfer, A.2
Wagner, U.3
Sauter, G.4
Moch, H.5
Willi, N.6
Gasser, T.C.7
Mihatsch, M.J.8
-
45
-
-
0002993759
-
The anatomy and pathways of skeletal metastases
-
GK Hall, Boston, L. Weiss, A. Gilbert (Eds.)
-
Galasko C.S. The anatomy and pathways of skeletal metastases. Bone Metastases 1981, 49-63. GK Hall, Boston. L. Weiss, A. Gilbert (Eds.).
-
(1981)
Bone Metastases
, pp. 49-63
-
-
Galasko, C.S.1
-
46
-
-
77953229266
-
Skeletal related events, bone metastasis and survival of prostate cancer: a population based cohort study in Denmark (1999 to 2007)
-
Norgaard M., Jensen A.O., Jacobsen J.B., Cetin K., Fryzek J.P., Sorensen H.T. Skeletal related events, bone metastasis and survival of prostate cancer: a population based cohort study in Denmark (1999 to 2007). J. Urol. 2010, 184:162-167.
-
(2010)
J. Urol.
, vol.184
, pp. 162-167
-
-
Norgaard, M.1
Jensen, A.O.2
Jacobsen, J.B.3
Cetin, K.4
Fryzek, J.P.5
Sorensen, H.T.6
-
47
-
-
79958037582
-
Bone metastasis in prostate cancer: emerging therapeutic strategies
-
Sturge J., Caley M.P., Waxman J. Bone metastasis in prostate cancer: emerging therapeutic strategies. Nat. Rev. Clin. Oncol. 2011, 8:357-368.
-
(2011)
Nat. Rev. Clin. Oncol.
, vol.8
, pp. 357-368
-
-
Sturge, J.1
Caley, M.P.2
Waxman, J.3
-
48
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock I.F., de Wit R., Berry W.R., Horti J., Pluzanska A., Chi K.N., Oudard S., Theodore C., James N.D., Turesson I., Rosenthal M.A., Eisenberger M.A. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N. Engl. J. Med. 2004, 351:1502-1512.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
de Wit, R.2
Berry, W.R.3
Horti, J.4
Pluzanska, A.5
Chi, K.N.6
Oudard, S.7
Theodore, C.8
James, N.D.9
Turesson, I.10
Rosenthal, M.A.11
Eisenberger, M.A.12
-
49
-
-
85028107326
-
Drug resistance in metastatic castration-resistant prostate cancer
-
Seruga B., Ocana A., Tannock I.F. Drug resistance in metastatic castration-resistant prostate cancer. Nat. Rev. Clin. Oncol. 2011, 8:12-23.
-
(2011)
Nat. Rev. Clin. Oncol.
, vol.8
, pp. 12-23
-
-
Seruga, B.1
Ocana, A.2
Tannock, I.F.3
-
50
-
-
77956533396
-
Therapeutic targeting of the prostate cancer microenvironment
-
Karlou M., Tzelepi V., Efstathiou E. Therapeutic targeting of the prostate cancer microenvironment. Nat. Rev. Urol. 2010, 7:494-509.
-
(2010)
Nat. Rev. Urol.
, vol.7
, pp. 494-509
-
-
Karlou, M.1
Tzelepi, V.2
Efstathiou, E.3
-
51
-
-
78649644931
-
Development of an in vitro model to study the impact of BMP-2 on metastasis to bone
-
Kwon H., Kim H.J., Rice W.L., Subramanian B., Park S.H., Georgakoudi I., Kaplan D.L. Development of an in vitro model to study the impact of BMP-2 on metastasis to bone. J. Tissue Eng. Regen. Med. 2010, 4:590-599.
-
(2010)
J. Tissue Eng. Regen. Med.
, vol.4
, pp. 590-599
-
-
Kwon, H.1
Kim, H.J.2
Rice, W.L.3
Subramanian, B.4
Park, S.H.5
Georgakoudi, I.6
Kaplan, D.L.7
-
52
-
-
77953674090
-
The human kallikrein gene family: new biomarkers for ovarian cancer
-
Yousef G.M., Diamandis E.P. The human kallikrein gene family: new biomarkers for ovarian cancer. Cancer Treat. Res. 2009, 149:165-187.
-
(2009)
Cancer Treat. Res.
, vol.149
, pp. 165-187
-
-
Yousef, G.M.1
Diamandis, E.P.2
-
53
-
-
0038036875
-
Parallel overexpression of seven kallikrein genes in ovarian cancer
-
Yousef G.M., Polymeris M.E., Yacoub G.M., Scorilas A., Soosaipillai A., Popalis C., Fracchioli S., Katsaros D., Diamandis E.P. Parallel overexpression of seven kallikrein genes in ovarian cancer. Cancer Res. 2003, 63:2223-2227.
-
(2003)
Cancer Res.
, vol.63
, pp. 2223-2227
-
-
Yousef, G.M.1
Polymeris, M.E.2
Yacoub, G.M.3
Scorilas, A.4
Soosaipillai, A.5
Popalis, C.6
Fracchioli, S.7
Katsaros, D.8
Diamandis, E.P.9
-
54
-
-
79960993915
-
Circulating biomarker tissue kallikrein-related peptidase KLK5 impacts ovarian cancer patients' survival
-
Dorn J., Magdolen V., Gkazepis A., Gerte T., Harlozinska A., Sedlaczek P., Diamandis E.P., Schuster T., Harbeck N., Kiechle M., Schmitt M. Circulating biomarker tissue kallikrein-related peptidase KLK5 impacts ovarian cancer patients' survival. Ann. Oncol. 2011, 22:1783-1790.
-
(2011)
Ann. Oncol.
, vol.22
, pp. 1783-1790
-
-
Dorn, J.1
Magdolen, V.2
Gkazepis, A.3
Gerte, T.4
Harlozinska, A.5
Sedlaczek, P.6
Diamandis, E.P.7
Schuster, T.8
Harbeck, N.9
Kiechle, M.10
Schmitt, M.11
-
55
-
-
84858343537
-
Evaluation of ovarian cancer remission markers HE4, MMP7 and Mesothelin by comparison to the established marker CA125
-
Schummer M., Drescher C., Forrest R., Gough S., Thorpe J., Hellstrom I., Hellstrom K.E., Urban N. Evaluation of ovarian cancer remission markers HE4, MMP7 and Mesothelin by comparison to the established marker CA125. Gynecol. Oncol. 2012, 125:65-69.
-
(2012)
Gynecol. Oncol.
, vol.125
, pp. 65-69
-
-
Schummer, M.1
Drescher, C.2
Forrest, R.3
Gough, S.4
Thorpe, J.5
Hellstrom, I.6
Hellstrom, K.E.7
Urban, N.8
-
56
-
-
0038756386
-
The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma
-
Hellstrom I., Raycraft J., Hayden-Ledbetter M., Ledbetter J.A., Schummer M., McIntosh M., Drescher C., Urban N., Hellstrom K.E. The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma. Cancer Res. 2003, 63:3695-3700.
-
(2003)
Cancer Res.
, vol.63
, pp. 3695-3700
-
-
Hellstrom, I.1
Raycraft, J.2
Hayden-Ledbetter, M.3
Ledbetter, J.A.4
Schummer, M.5
McIntosh, M.6
Drescher, C.7
Urban, N.8
Hellstrom, K.E.9
-
57
-
-
37249080637
-
A multiparametric panel for ovarian cancer diagnosis, prognosis, and response to chemotherapy
-
Zheng Y., Katsaros D., Shan S.J., de la Longrais I.R., Porpiglia M., Scorilas A., Kim N.W., Wolfert R.L., Simon I., Li L., Feng Z., Diamandis E.P. A multiparametric panel for ovarian cancer diagnosis, prognosis, and response to chemotherapy. Clin. Cancer Res. 2007, 13:6984-6992.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 6984-6992
-
-
Zheng, Y.1
Katsaros, D.2
Shan, S.J.3
de la Longrais, I.R.4
Porpiglia, M.5
Scorilas, A.6
Kim, N.W.7
Wolfert, R.L.8
Simon, I.9
Li, L.10
Feng, Z.11
Diamandis, E.P.12
-
58
-
-
84859827944
-
Stromal cell-associated expression of kallikrein-related peptidase 6 (KLK6) indicates poor prognosis of ovarian cancer patients
-
Seiz L., Dorn J., Kotzsch M., Walch A., Grebenchtchikov N.I., Gkazepis A., Schmalfeldt B., Kiechle M., Bayani J., Diamandis E.P., Langer R., Sweep F.C., Schmitt M., Magdolen V. Stromal cell-associated expression of kallikrein-related peptidase 6 (KLK6) indicates poor prognosis of ovarian cancer patients. Biol. Chem. 2012, 393:391-401.
-
(2012)
Biol. Chem.
, vol.393
, pp. 391-401
-
-
Seiz, L.1
Dorn, J.2
Kotzsch, M.3
Walch, A.4
Grebenchtchikov, N.I.5
Gkazepis, A.6
Schmalfeldt, B.7
Kiechle, M.8
Bayani, J.9
Diamandis, E.P.10
Langer, R.11
Sweep, F.C.12
Schmitt, M.13
Magdolen, V.14
-
59
-
-
84890406716
-
Clinical value of protein expression of kallikrein-related peptidase 7 (KLK7) in ovarian cancer
-
Dorn J., Gkazepis A., Kotzsch M., Kremer M., Propping C., Mayer K., Mengele K., Diamandis E.P., Kiechle M., Magdolen V., Schmitt M. Clinical value of protein expression of kallikrein-related peptidase 7 (KLK7) in ovarian cancer. Biol. Chem. 2014, 395:95-107.
-
(2014)
Biol. Chem.
, vol.395
, pp. 95-107
-
-
Dorn, J.1
Gkazepis, A.2
Kotzsch, M.3
Kremer, M.4
Propping, C.5
Mayer, K.6
Mengele, K.7
Diamandis, E.P.8
Kiechle, M.9
Magdolen, V.10
Schmitt, M.11
-
60
-
-
84872025210
-
Reflection on the discovery of carcinoembryonic antigen, prostate-specific antigen, and cancer antigens CA125 and CA19-9
-
Diamandis E.P., Bast R.C., Gold P., Chu T.M., Magnani J.L. Reflection on the discovery of carcinoembryonic antigen, prostate-specific antigen, and cancer antigens CA125 and CA19-9. Clin. Chem. 2013, 59:22-31.
-
(2013)
Clin. Chem.
, vol.59
, pp. 22-31
-
-
Diamandis, E.P.1
Bast, R.C.2
Gold, P.3
Chu, T.M.4
Magnani, J.L.5
-
61
-
-
84860223306
-
Screening for cancer with molecular markers: progress comes with potential problems
-
Baron J.A. Screening for cancer with molecular markers: progress comes with potential problems. Nat. Rev. Cancer 2012, 12:368-371.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 368-371
-
-
Baron, J.A.1
-
62
-
-
78049470983
-
Prostate cancer incidence and mortality trends in 37 European countries: an overview
-
Bray F., Lortet-Tieulent J., Ferlay J., Forman D., Auvinen A. Prostate cancer incidence and mortality trends in 37 European countries: an overview. Eur. J. Cancer 2010, 46:3040-3052.
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 3040-3052
-
-
Bray, F.1
Lortet-Tieulent, J.2
Ferlay, J.3
Forman, D.4
Auvinen, A.5
-
63
-
-
84873703691
-
Active surveillance for prostate cancer: overview and update
-
Klotz L. Active surveillance for prostate cancer: overview and update. Curr. Treat. Options Oncol. 2013, 14:97-108.
-
(2013)
Curr. Treat. Options Oncol.
, vol.14
, pp. 97-108
-
-
Klotz, L.1
-
64
-
-
44949142265
-
Five-alpha-reductase inhibitors for prostate cancer prevention
-
Wilt T.J., MacDonald R., Hagerty K., Schellhammer P., Kramer B.S. Five-alpha-reductase inhibitors for prostate cancer prevention. Cochrane Database Syst. Rev. 2008, CD007091.
-
(2008)
Cochrane Database Syst. Rev.
, pp. CD007091
-
-
Wilt, T.J.1
MacDonald, R.2
Hagerty, K.3
Schellhammer, P.4
Kramer, B.S.5
-
65
-
-
84894386160
-
Circulating biomarkers for detection of ovarian cancer and predicting cancer outcomes
-
Shapira I., Oswald M., Lovecchio J., Khalili H., Menzin A., Whyte J., Dos Santos L., Liang S., Bhuiya T., Keogh M., Mason C., Sultan K., Budman D., Gregersen P.K., Lee A.T. Circulating biomarkers for detection of ovarian cancer and predicting cancer outcomes. Br. J. Cancer 2014, 110:976-983.
-
(2014)
Br. J. Cancer
, vol.110
, pp. 976-983
-
-
Shapira, I.1
Oswald, M.2
Lovecchio, J.3
Khalili, H.4
Menzin, A.5
Whyte, J.6
Dos Santos, L.7
Liang, S.8
Bhuiya, T.9
Keogh, M.10
Mason, C.11
Sultan, K.12
Budman, D.13
Gregersen, P.K.14
Lee, A.T.15
-
66
-
-
84900548218
-
Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer
-
Lin H.M., Castillo L., Mahon K.L., Chiam K., Lee B.Y., Nguyen Q., Boyer M.J., Stockler M.R., Pavlakis N., Marx G., Mallesara G., Gurney H., Clark S.J., Swarbrick A., Daly R.J., Horvath L.G. Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer. Br. J. Cancer 2014, 110:2462-2471.
-
(2014)
Br. J. Cancer
, vol.110
, pp. 2462-2471
-
-
Lin, H.M.1
Castillo, L.2
Mahon, K.L.3
Chiam, K.4
Lee, B.Y.5
Nguyen, Q.6
Boyer, M.J.7
Stockler, M.R.8
Pavlakis, N.9
Marx, G.10
Mallesara, G.11
Gurney, H.12
Clark, S.J.13
Swarbrick, A.14
Daly, R.J.15
Horvath, L.G.16
-
67
-
-
0028203594
-
Early de novo ovarian carcinoma. A study of fourteen cases
-
Bell D.A., Scully R.E. Early de novo ovarian carcinoma. A study of fourteen cases. Cancer 1994, 73:1859-1864.
-
(1994)
Cancer
, vol.73
, pp. 1859-1864
-
-
Bell, D.A.1
Scully, R.E.2
-
68
-
-
19744368302
-
Cancer of the ovary
-
Cannistra S.A. Cancer of the ovary. N. Engl. J. Med. 2004, 351:2519-2529.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2519-2529
-
-
Cannistra, S.A.1
-
69
-
-
67349190538
-
Precursors to pelvic serous carcinoma and their clinical implications
-
Folkins A.K., Jarboe E.A., Roh M.H., Crum C.P. Precursors to pelvic serous carcinoma and their clinical implications. Gynecol. Oncol. 2009, 113:391-396.
-
(2009)
Gynecol. Oncol.
, vol.113
, pp. 391-396
-
-
Folkins, A.K.1
Jarboe, E.A.2
Roh, M.H.3
Crum, C.P.4
-
70
-
-
33846624310
-
Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship
-
Kindelberger D.W., Lee Y., Miron A., Hirsch M.S., Feltmate C., Medeiros F., Callahan M.J., Garner E.O., Gordon R.W., Birch C., Berkowitz R.S., Muto M.G., Crum C.P. Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship. Am. J. Surg. Pathol. 2007, 31:161-169.
-
(2007)
Am. J. Surg. Pathol.
, vol.31
, pp. 161-169
-
-
Kindelberger, D.W.1
Lee, Y.2
Miron, A.3
Hirsch, M.S.4
Feltmate, C.5
Medeiros, F.6
Callahan, M.J.7
Garner, E.O.8
Gordon, R.W.9
Birch, C.10
Berkowitz, R.S.11
Muto, M.G.12
Crum, C.P.13
-
71
-
-
84863230370
-
High-grade serous ovarian cancer arises from fallopian tube in a mouse model
-
Kim J., Coffey D.M., Creighton C.J., Yu Z., Hawkins S.M., Matzuk M.M. High-grade serous ovarian cancer arises from fallopian tube in a mouse model. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:3921-3926.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 3921-3926
-
-
Kim, J.1
Coffey, D.M.2
Creighton, C.J.3
Yu, Z.4
Hawkins, S.M.5
Matzuk, M.M.6
-
72
-
-
84866087898
-
Primary culture and immortalization of human fallopian tube secretory epithelial cells
-
Karst A.M., Drapkin R. Primary culture and immortalization of human fallopian tube secretory epithelial cells. Nat. Protoc. 2012, 7:1755-1764.
-
(2012)
Nat. Protoc.
, vol.7
, pp. 1755-1764
-
-
Karst, A.M.1
Drapkin, R.2
-
73
-
-
84891937100
-
Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models
-
Perets R., Wyant G.A., Muto K.W., Bijron J.G., Poole B.B., Chin K.T., Chen J.Y., Ohman A.W., Stepule C.D., Kwak S., Karst A.M., Hirsch M.S., Setlur S.R., Crum C.P., Dinulescu D.M., Drapkin R. Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models. Cancer Cell 2013, 24:751-765.
-
(2013)
Cancer Cell
, vol.24
, pp. 751-765
-
-
Perets, R.1
Wyant, G.A.2
Muto, K.W.3
Bijron, J.G.4
Poole, B.B.5
Chin, K.T.6
Chen, J.Y.7
Ohman, A.W.8
Stepule, C.D.9
Kwak, S.10
Karst, A.M.11
Hirsch, M.S.12
Setlur, S.R.13
Crum, C.P.14
Dinulescu, D.M.15
Drapkin, R.16
-
74
-
-
39749171410
-
Early events in the pathogenesis of epithelial ovarian cancer
-
Landen C.N., Birrer M.J., Sood A.K. Early events in the pathogenesis of epithelial ovarian cancer. J. Clin. Oncol. 2008, 26:995-1005.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 995-1005
-
-
Landen, C.N.1
Birrer, M.J.2
Sood, A.K.3
-
75
-
-
77649219639
-
The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory
-
Kurman R.J., Shih Ie M. The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory. Am. J. Surg. Pathol. 2010, 34:433-443.
-
(2010)
Am. J. Surg. Pathol.
, vol.34
, pp. 433-443
-
-
Kurman, R.J.1
Shih Ie, M.2
-
77
-
-
41349105997
-
Histologic subtypes of ovarian carcinoma: an overview
-
Soslow R.A. Histologic subtypes of ovarian carcinoma: an overview. Int. J. Gynecol. Pathol. 2008, 27:161-174.
-
(2008)
Int. J. Gynecol. Pathol.
, vol.27
, pp. 161-174
-
-
Soslow, R.A.1
-
78
-
-
75149133405
-
Pathogenesis of ovarian cancer: clues from selected overexpressed genes
-
Shih Ie M., Davidson B. Pathogenesis of ovarian cancer: clues from selected overexpressed genes. Future Oncol. 2009, 5:1641-1657.
-
(2009)
Future Oncol.
, vol.5
, pp. 1641-1657
-
-
Shih Ie, M.1
Davidson, B.2
-
79
-
-
84878772697
-
Ovarian cancer as a genetic disease
-
Lech A., Daneva T., Pashova S., Gagov H., Crayton R., Kukwa W., Czarnecka A.M., Szczylik C. Ovarian cancer as a genetic disease. Front. Biosci. 2013, 18:543-563.
-
(2013)
Front. Biosci.
, vol.18
, pp. 543-563
-
-
Lech, A.1
Daneva, T.2
Pashova, S.3
Gagov, H.4
Crayton, R.5
Kukwa, W.6
Czarnecka, A.M.7
Szczylik, C.8
-
80
-
-
84883528065
-
Predicting time to ovarian carcinoma recurrence using protein markers
-
Yang J.Y., Yoshihara K., Tanaka K., Hatae M., Masuzaki H., Itamochi H., Takano M., Ushijima K., Tanyi J.L., Coukos G., Lu Y., Mills G.B., Verhaak R.G. Predicting time to ovarian carcinoma recurrence using protein markers. J. Clin. Invest. 2013, 123:3740-3750.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3740-3750
-
-
Yang, J.Y.1
Yoshihara, K.2
Tanaka, K.3
Hatae, M.4
Masuzaki, H.5
Itamochi, H.6
Takano, M.7
Ushijima, K.8
Tanyi, J.L.9
Coukos, G.10
Lu, Y.11
Mills, G.B.12
Verhaak, R.G.13
-
81
-
-
61449231569
-
Ovarian cancer: a clinical challenge that needs some basic answers
-
Lawrenson K., Gayther S.A. Ovarian cancer: a clinical challenge that needs some basic answers. PLoS Med. 2009, 6:e25.
-
(2009)
PLoS Med.
, vol.6
, pp. e25
-
-
Lawrenson, K.1
Gayther, S.A.2
-
82
-
-
77955039099
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
-
Audeh M.W., Carmichael J., Penson R.T., Friedlander M., Powell B., Bell-McGuinn K.M., Scott C., Weitzel J.N., Oaknin A., Loman N., Lu K., Schmutzler R.K., Matulonis U., Wickens M., Tutt A. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet 2010, 376:245-251.
-
(2010)
Lancet
, vol.376
, pp. 245-251
-
-
Audeh, M.W.1
Carmichael, J.2
Penson, R.T.3
Friedlander, M.4
Powell, B.5
Bell-McGuinn, K.M.6
Scott, C.7
Weitzel, J.N.8
Oaknin, A.9
Loman, N.10
Lu, K.11
Schmutzler, R.K.12
Matulonis, U.13
Wickens, M.14
Tutt, A.15
-
83
-
-
84864026311
-
BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group
-
Alsop K., Fereday S., Meldrum C., deFazio A., Emmanuel C., George J., Dobrovic A., Birrer M.J., Webb P.M., Stewart C., Friedlander M., Fox S., Bowtell D., Mitchell G. BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group. J. Clin. Oncol. 2012, 30:2654-2663.
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 2654-2663
-
-
Alsop, K.1
Fereday, S.2
Meldrum, C.3
deFazio, A.4
Emmanuel, C.5
George, J.6
Dobrovic, A.7
Birrer, M.J.8
Webb, P.M.9
Stewart, C.10
Friedlander, M.11
Fox, S.12
Bowtell, D.13
Mitchell, G.14
-
84
-
-
84874821284
-
New strategies in the treatment of ovarian cancer: current clinical perspectives and future potential
-
Banerjee S., Kaye S.B. New strategies in the treatment of ovarian cancer: current clinical perspectives and future potential. Clin. Cancer Res. 2013, 19:961-968.
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 961-968
-
-
Banerjee, S.1
Kaye, S.B.2
-
85
-
-
84880333946
-
Poly(adenosine diphosphate-ribose) polymerase expression in BRCA-proficient ovarian high-grade serous carcinoma; association with patient survival
-
Gan A., Green A.R., Nolan C.C., Martin S., Deen S. Poly(adenosine diphosphate-ribose) polymerase expression in BRCA-proficient ovarian high-grade serous carcinoma; association with patient survival. Hum. Pathol. 2013, 44:1638-1647.
-
(2013)
Hum. Pathol.
, vol.44
, pp. 1638-1647
-
-
Gan, A.1
Green, A.R.2
Nolan, C.C.3
Martin, S.4
Deen, S.5
-
86
-
-
84867320871
-
Isolation and characterization of tumor cells from the ascites of ovarian cancer patients: molecular phenotype of chemoresistant ovarian tumors
-
Latifi A., Luwor R.B., Bilandzic M., Nazaretian S., Stenvers K., Pyman J., Zhu H., Thompson E.W., Quinn M.A., Findlay J.K., Ahmed N. Isolation and characterization of tumor cells from the ascites of ovarian cancer patients: molecular phenotype of chemoresistant ovarian tumors. PLoS One 2012, 7:e46858.
-
(2012)
PLoS One
, vol.7
, pp. e46858
-
-
Latifi, A.1
Luwor, R.B.2
Bilandzic, M.3
Nazaretian, S.4
Stenvers, K.5
Pyman, J.6
Zhu, H.7
Thompson, E.W.8
Quinn, M.A.9
Findlay, J.K.10
Ahmed, N.11
-
87
-
-
80053211466
-
Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile
-
Latifi A., Abubaker K., Castrechini N., Ward A.C., Liongue C., Dobill F., Kumar J., Thompson E.W., Quinn M.A., Findlay J.K., Ahmed N. Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile. J. Cell. Biochem. 2011, 112:2850-2864.
-
(2011)
J. Cell. Biochem.
, vol.112
, pp. 2850-2864
-
-
Latifi, A.1
Abubaker, K.2
Castrechini, N.3
Ward, A.C.4
Liongue, C.5
Dobill, F.6
Kumar, J.7
Thompson, E.W.8
Quinn, M.A.9
Findlay, J.K.10
Ahmed, N.11
-
88
-
-
0242523090
-
Human prostate cancer precursors and pathobiology
-
De Marzo A.M., Meeker A.K., Zha S., Luo J., Nakayama M., Platz E.A., Isaacs W.B., Nelson W.G. Human prostate cancer precursors and pathobiology. Urology 2003, 62:55-62.
-
(2003)
Urology
, vol.62
, pp. 55-62
-
-
De Marzo, A.M.1
Meeker, A.K.2
Zha, S.3
Luo, J.4
Nakayama, M.5
Platz, E.A.6
Isaacs, W.B.7
Nelson, W.G.8
-
89
-
-
65549142546
-
Gene expression changes are age-dependent and lobe-specific in the brown Norway rat model of prostatic hyperplasia
-
Bethel C.R., Chaudhary J., Anway M.D., Brown T.R. Gene expression changes are age-dependent and lobe-specific in the brown Norway rat model of prostatic hyperplasia. Prostate 2009, 69:838-850.
-
(2009)
Prostate
, vol.69
, pp. 838-850
-
-
Bethel, C.R.1
Chaudhary, J.2
Anway, M.D.3
Brown, T.R.4
-
90
-
-
77956793432
-
Molecular genetics of prostate cancer: new prospects for old challenges
-
Shen M.M., Abate-Shen C. Molecular genetics of prostate cancer: new prospects for old challenges. Genes Dev. 2010, 24:1967-2000.
-
(2010)
Genes Dev.
, vol.24
, pp. 1967-2000
-
-
Shen, M.M.1
Abate-Shen, C.2
-
91
-
-
7444243188
-
Unusual subtypes of prostate cancer
-
Grignon D.J. Unusual subtypes of prostate cancer. Mod. Pathol. 2004, 17:316-327.
-
(2004)
Mod. Pathol.
, vol.17
, pp. 316-327
-
-
Grignon, D.J.1
-
92
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor B.S., Schultz N., Hieronymus H., Gopalan A., Xiao Y., Carver B.S., Arora V.K., Kaushik P., Cerami E., Reva B., Antipin Y., Mitsiades N., Landers T., Dolgalev I., Major J.E., Wilson M., Socci N.D., Lash A.E., Heguy A., Eastham J.A., Scher H.I., Reuter V.E., Scardino P.T., Sander C., Sawyers C.L., Gerald W.L. Integrative genomic profiling of human prostate cancer. Cancer Cell 2010, 18:11-22.
-
(2010)
Cancer Cell
, vol.18
, pp. 11-22
-
-
Taylor, B.S.1
Schultz, N.2
Hieronymus, H.3
Gopalan, A.4
Xiao, Y.5
Carver, B.S.6
Arora, V.K.7
Kaushik, P.8
Cerami, E.9
Reva, B.10
Antipin, Y.11
Mitsiades, N.12
Landers, T.13
Dolgalev, I.14
Major, J.E.15
Wilson, M.16
Socci, N.D.17
Lash, A.E.18
Heguy, A.19
Eastham, J.A.20
Scher, H.I.21
Reuter, V.E.22
Scardino, P.T.23
Sander, C.24
Sawyers, C.L.25
Gerald, W.L.26
more..
-
93
-
-
33845289802
-
Decreased NKX3.1 protein expression in focal prostatic atrophy, prostatic intraepithelial neoplasia, and adenocarcinoma: association with Gleason score and chromosome 8p deletion
-
Bethel C.R., Faith D., Li X., Guan B., Hicks J.L., Lan F., Jenkins R.B., Bieberich C.J., De Marzo A.M. Decreased NKX3.1 protein expression in focal prostatic atrophy, prostatic intraepithelial neoplasia, and adenocarcinoma: association with Gleason score and chromosome 8p deletion. Cancer Res. 2006, 66:10683-10690.
-
(2006)
Cancer Res.
, vol.66
, pp. 10683-10690
-
-
Bethel, C.R.1
Faith, D.2
Li, X.3
Guan, B.4
Hicks, J.L.5
Lan, F.6
Jenkins, R.B.7
Bieberich, C.J.8
De Marzo, A.M.9
-
94
-
-
0030822020
-
Coding region of NKX3.1, a prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers
-
Voeller H.J., Augustus M., Madike V., Bova G.S., Carter K.C., Gelmann E.P. Coding region of NKX3.1, a prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers. Cancer Res. 1997, 57:4455-4459.
-
(1997)
Cancer Res.
, vol.57
, pp. 4455-4459
-
-
Voeller, H.J.1
Augustus, M.2
Madike, V.3
Bova, G.S.4
Carter, K.C.5
Gelmann, E.P.6
-
95
-
-
0036605972
-
Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis
-
Kim M.J., Bhatia-Gaur R., Banach-Petrosky W.A., Desai N., Wang Y., Hayward S.W., Cunha G.R., Cardiff R.D., Shen M.M., Abate-Shen C. Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Res. 2002, 62:2999-3004.
-
(2002)
Cancer Res.
, vol.62
, pp. 2999-3004
-
-
Kim, M.J.1
Bhatia-Gaur, R.2
Banach-Petrosky, W.A.3
Desai, N.4
Wang, Y.5
Hayward, S.W.6
Cunha, G.R.7
Cardiff, R.D.8
Shen, M.M.9
Abate-Shen, C.10
-
96
-
-
50249133616
-
Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis
-
Gurel B., Iwata T., Koh C.M., Jenkins R.B., Lan F., Van Dang C., Hicks J.L., Morgan J., Cornish T.C., Sutcliffe S., Isaacs W.B., Luo J., De Marzo A.M. Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Mod. Pathol. 2008, 21:1156-1167.
-
(2008)
Mod. Pathol.
, vol.21
, pp. 1156-1167
-
-
Gurel, B.1
Iwata, T.2
Koh, C.M.3
Jenkins, R.B.4
Lan, F.5
Van Dang, C.6
Hicks, J.L.7
Morgan, J.8
Cornish, T.C.9
Sutcliffe, S.10
Isaacs, W.B.11
Luo, J.12
De Marzo, A.M.13
-
97
-
-
34248569769
-
Morphological features of TMPRSS2-ERG gene fusion prostate cancer
-
Mosquera J.M., Perner S., Demichelis F., Kim R., Hofer M.D., Mertz K.D., Paris P.L., Simko J., Collins C., Bismar T.A., Chinnaiyan A.M., Rubin M.A. Morphological features of TMPRSS2-ERG gene fusion prostate cancer. J. Pathol. 2007, 212:91-101.
-
(2007)
J. Pathol.
, vol.212
, pp. 91-101
-
-
Mosquera, J.M.1
Perner, S.2
Demichelis, F.3
Kim, R.4
Hofer, M.D.5
Mertz, K.D.6
Paris, P.L.7
Simko, J.8
Collins, C.9
Bismar, T.A.10
Chinnaiyan, A.M.11
Rubin, M.A.12
-
98
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
Tomlins S.A., Rhodes D.R., Perner S., Dhanasekaran S.M., Mehra R., Sun X.W., Varambally S., Cao X., Tchinda J., Kuefer R., Lee C., Montie J.E., Shah R.B., Pienta K.J., Rubin M.A., Chinnaiyan A.M. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005, 310:644-648.
-
(2005)
Science
, vol.310
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
Pienta, K.J.14
Rubin, M.A.15
Chinnaiyan, A.M.16
-
99
-
-
50349093250
-
Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications
-
Mosquera J.M., Perner S., Genega E.M., Sanda M., Hofer M.D., Mertz K.D., Paris P.L., Simko J., Bismar T.A., Ayala G., Shah R.B., Loda M., Rubin M.A. Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications. Clin. Cancer Res. 2008, 14:3380-3385.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3380-3385
-
-
Mosquera, J.M.1
Perner, S.2
Genega, E.M.3
Sanda, M.4
Hofer, M.D.5
Mertz, K.D.6
Paris, P.L.7
Simko, J.8
Bismar, T.A.9
Ayala, G.10
Shah, R.B.11
Loda, M.12
Rubin, M.A.13
-
100
-
-
70350686099
-
TMPRSS2-ERG gene fusion status in minute (minimal) prostatic adenocarcinoma
-
Albadine R., Latour M., Toubaji A., Haffner M., Isaacs W.B., Meeker A.P.E.A.K., Demarzo A.M., Epstein J.I., Netto G.J. TMPRSS2-ERG gene fusion status in minute (minimal) prostatic adenocarcinoma. Mod. Pathol. 2009, 22:1415-1422.
-
(2009)
Mod. Pathol.
, vol.22
, pp. 1415-1422
-
-
Albadine, R.1
Latour, M.2
Toubaji, A.3
Haffner, M.4
Isaacs, W.B.5
Meeker, A.P.E.A.K.6
Demarzo, A.M.7
Epstein, J.I.8
Netto, G.J.9
-
101
-
-
33748038440
-
Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice
-
Gao H., Ouyang X., Banach-Petrosky W.A., Shen M.M., Abate-Shen C. Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice. Cancer Res. 2006, 66:7929-7933.
-
(2006)
Cancer Res.
, vol.66
, pp. 7929-7933
-
-
Gao, H.1
Ouyang, X.2
Banach-Petrosky, W.A.3
Shen, M.M.4
Abate-Shen, C.5
-
102
-
-
67650917081
-
PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer
-
Sircar K., Yoshimoto M., Monzon F.A., Koumakpayi I.H., Katz R.L., Khanna A., Alvarez K., Chen G., Darnel A.D., Aprikian A.G., Saad F., Bismar T.A., Squire J.A. PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer. J. Pathol. 2009, 218:505-513.
-
(2009)
J. Pathol.
, vol.218
, pp. 505-513
-
-
Sircar, K.1
Yoshimoto, M.2
Monzon, F.A.3
Koumakpayi, I.H.4
Katz, R.L.5
Khanna, A.6
Alvarez, K.7
Chen, G.8
Darnel, A.D.9
Aprikian, A.G.10
Saad, F.11
Bismar, T.A.12
Squire, J.A.13
-
103
-
-
4344591508
-
Enhanced redundancy in Akt and mitogen-activated protein kinase-induced survival of malignant versus normal prostate epithelial cells
-
Uzgare A.R., Isaacs J.T. Enhanced redundancy in Akt and mitogen-activated protein kinase-induced survival of malignant versus normal prostate epithelial cells. Cancer Res. 2004, 64:6190-6199.
-
(2004)
Cancer Res.
, vol.64
, pp. 6190-6199
-
-
Uzgare, A.R.1
Isaacs, J.T.2
-
104
-
-
84886059336
-
Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway
-
Ni J., Cozzi P., Hao J., Beretov J., Chang L., Duan W., Shigdar S., Delprado W., Graham P., Bucci J., Kearsley J., Li Y. Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway. Int. J. Biochem. Cell Biol. 2013, 45:2736-2748.
-
(2013)
Int. J. Biochem. Cell Biol.
, vol.45
, pp. 2736-2748
-
-
Ni, J.1
Cozzi, P.2
Hao, J.3
Beretov, J.4
Chang, L.5
Duan, W.6
Shigdar, S.7
Delprado, W.8
Graham, P.9
Bucci, J.10
Kearsley, J.11
Li, Y.12
-
105
-
-
84899607537
-
Talin1 phosphorylation activates beta1 integrins: a novel mechanism to promote prostate cancer bone metastasis
-
[Epub ahead of print]
-
Jin J.K., Tien P.C., Cheng C.J., Song J.H., Huang C., Lin S.H., Gallick G.E. Talin1 phosphorylation activates beta1 integrins: a novel mechanism to promote prostate cancer bone metastasis. Oncogene 2014, [Epub ahead of print].
-
(2014)
Oncogene
-
-
Jin, J.K.1
Tien, P.C.2
Cheng, C.J.3
Song, J.H.4
Huang, C.5
Lin, S.H.6
Gallick, G.E.7
-
106
-
-
84872702300
-
Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer
-
Li C.R., Su J.J., Wang W.Y., Lee M.T., Wang T.Y., Jiang K.Y., Li C.F., Hsu J.M., Chen C.K., Chen M., Jiang S.S., Weaver V.M., Tsai K.K. Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer. Am. J. Pathol. 2013, 182:363-374.
-
(2013)
Am. J. Pathol.
, vol.182
, pp. 363-374
-
-
Li, C.R.1
Su, J.J.2
Wang, W.Y.3
Lee, M.T.4
Wang, T.Y.5
Jiang, K.Y.6
Li, C.F.7
Hsu, J.M.8
Chen, C.K.9
Chen, M.10
Jiang, S.S.11
Weaver, V.M.12
Tsai, K.K.13
-
107
-
-
84897572526
-
Osteoblasts stimulate the osteogenic and metastatic progression of castration-resistant prostate cancer in a novel model for in vitro and in vivo studies
-
Hagberg Thulin M., Jennbacken K., Damber J.E., Welen K. Osteoblasts stimulate the osteogenic and metastatic progression of castration-resistant prostate cancer in a novel model for in vitro and in vivo studies. Clin. Exp. Metastasis 2014, 31:269-283.
-
(2014)
Clin. Exp. Metastasis
, vol.31
, pp. 269-283
-
-
Hagberg Thulin, M.1
Jennbacken, K.2
Damber, J.E.3
Welen, K.4
-
108
-
-
44949166671
-
Three-dimensional cell culture matrices: state of the art
-
Lee J., Cuddihy M.J., Kotov N.A. Three-dimensional cell culture matrices: state of the art. Tissue Eng. Part B 2008, 14:61-86.
-
(2008)
Tissue Eng. Part B
, vol.14
, pp. 61-86
-
-
Lee, J.1
Cuddihy, M.J.2
Kotov, N.A.3
-
109
-
-
77954518306
-
Tumor engineering: the other face of tissue engineering
-
Ghajar C.M., Bissell M.J. Tumor engineering: the other face of tissue engineering. Tissue Eng. Part A 2010, 16:2153-2156.
-
(2010)
Tissue Eng. Part A
, vol.16
, pp. 2153-2156
-
-
Ghajar, C.M.1
Bissell, M.J.2
-
110
-
-
48349113618
-
Can cancer be reversed by engineering the tumor microenvironment?
-
Ingber D.E. Can cancer be reversed by engineering the tumor microenvironment?. Semin. Cancer Biol. 2008, 18:356-364.
-
(2008)
Semin. Cancer Biol.
, vol.18
, pp. 356-364
-
-
Ingber, D.E.1
-
111
-
-
77952932509
-
Engineering tumors: a tissue engineering perspective in cancer biology
-
Burdett E., Kasper F.K., Mikos A.G., Ludwig J.A. Engineering tumors: a tissue engineering perspective in cancer biology. Tissue Eng. Part B Rev. 2010, 16:351-359.
-
(2010)
Tissue Eng. Part B Rev.
, vol.16
, pp. 351-359
-
-
Burdett, E.1
Kasper, F.K.2
Mikos, A.G.3
Ludwig, J.A.4
-
113
-
-
34547931078
-
Modeling tissue morphogenesis and cancer in 3D
-
Yamada K.M., Cukierman E. Modeling tissue morphogenesis and cancer in 3D. Cell 2007, 130:601-610.
-
(2007)
Cell
, vol.130
, pp. 601-610
-
-
Yamada, K.M.1
Cukierman, E.2
-
114
-
-
48149105146
-
Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells
-
Serebriiskii I., Castello-Cros R., Lamb A., Golemis E.A., Cukierman E. Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells. Matrix Biol. 2008, 27:573-585.
-
(2008)
Matrix Biol.
, vol.27
, pp. 573-585
-
-
Serebriiskii, I.1
Castello-Cros, R.2
Lamb, A.3
Golemis, E.A.4
Cukierman, E.5
-
115
-
-
84864751521
-
In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors
-
Lescarbeau R.M., Seib F.P., Prewitz M., Werner C., Kaplan D.L. In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors. PLoS One 2012, 7:e40372.
-
(2012)
PLoS One
, vol.7
, pp. e40372
-
-
Lescarbeau, R.M.1
Seib, F.P.2
Prewitz, M.3
Werner, C.4
Kaplan, D.L.5
-
116
-
-
77956011271
-
Mineralized human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells with the bone microenvironment
-
Reichert J.C., Quent V.M., Burke L.J., Stansfield S.H., Clements J.A., Hutmacher D.W. Mineralized human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells with the bone microenvironment. Biomaterials 2010, 31:7928-7936.
-
(2010)
Biomaterials
, vol.31
, pp. 7928-7936
-
-
Reichert, J.C.1
Quent, V.M.2
Burke, L.J.3
Stansfield, S.H.4
Clements, J.A.5
Hutmacher, D.W.6
-
117
-
-
84878229047
-
Delineating breast cancer cell interactions with engineered bone microenvironments
-
Taubenberger A.V., Quent V.M., Thibaudeau L., Clements J.A., Hutmacher D.W. Delineating breast cancer cell interactions with engineered bone microenvironments. J. Bone Miner. Res. 2013, 28:1399-1411.
-
(2013)
J. Bone Miner. Res.
, vol.28
, pp. 1399-1411
-
-
Taubenberger, A.V.1
Quent, V.M.2
Thibaudeau, L.3
Clements, J.A.4
Hutmacher, D.W.5
-
118
-
-
0038784546
-
Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix
-
Hotary K.B., Allen E.D., Brooks P.C., Datta N.S., Long M.W., Weiss S.J. Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix. Cell 2003, 114:33-45.
-
(2003)
Cell
, vol.114
, pp. 33-45
-
-
Hotary, K.B.1
Allen, E.D.2
Brooks, P.C.3
Datta, N.S.4
Long, M.W.5
Weiss, S.J.6
-
120
-
-
77956287380
-
A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses
-
Harma V., Virtanen J., Makela R., Happonen A., Mpindi J.P., Knuuttila M., Kohonen P., Lotjonen J., Kallioniemi O., Nees M. A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses. PLoS One 2010, 5:e10431.
-
(2010)
PLoS One
, vol.5
, pp. e10431
-
-
Harma, V.1
Virtanen, J.2
Makela, R.3
Happonen, A.4
Mpindi, J.P.5
Knuuttila, M.6
Kohonen, P.7
Lotjonen, J.8
Kallioniemi, O.9
Nees, M.10
-
121
-
-
84881149808
-
The role of engineering approaches in analysing cancer invasion and metastasis
-
Zaman M.H. The role of engineering approaches in analysing cancer invasion and metastasis. Nat. Rev. Cancer 2013, 13:596-603.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 596-603
-
-
Zaman, M.H.1
-
122
-
-
79551649124
-
A three-dimensional in vitro ovarian cancer coculture model using a high-throughput cell patterning platform
-
Xu F., Celli J., Rizvi I., Moon S., Hasan T., Demirci U. A three-dimensional in vitro ovarian cancer coculture model using a high-throughput cell patterning platform. Biotechnol. J. 2011, 6:204-212.
-
(2011)
Biotechnol. J.
, vol.6
, pp. 204-212
-
-
Xu, F.1
Celli, J.2
Rizvi, I.3
Moon, S.4
Hasan, T.5
Demirci, U.6
-
123
-
-
84863464639
-
31P-magnetic resonance spectra of ovarian cancer cells exposed to chemotherapy within a three-dimensional Matrigel construct
-
Abramov Y., Carmi S., Cohen J.S., Anteby S.O., Ringel I. 31P-magnetic resonance spectra of ovarian cancer cells exposed to chemotherapy within a three-dimensional Matrigel construct. Oncol. Rep. 2012, 28:735-741.
-
(2012)
Oncol. Rep.
, vol.28
, pp. 735-741
-
-
Abramov, Y.1
Carmi, S.2
Cohen, J.S.3
Anteby, S.O.4
Ringel, I.5
-
124
-
-
84866343225
-
In vivo biomarker expression patterns are preserved in 3D cultures of prostate cancer
-
Windus L.C., Kiss D.L., Glover T., Avery V.M. In vivo biomarker expression patterns are preserved in 3D cultures of prostate cancer. Exp. Cell Res. 2012, 318:2507-2519.
-
(2012)
Exp. Cell Res.
, vol.318
, pp. 2507-2519
-
-
Windus, L.C.1
Kiss, D.L.2
Glover, T.3
Avery, V.M.4
-
125
-
-
84884695570
-
Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer
-
Windus L.C., Glover T.T., Avery V.M. Bone-stromal cells up-regulate tumourigenic markers in a tumour-stromal 3D model of prostate cancer. Mol. Cancer 2013, 12:112.
-
(2013)
Mol. Cancer
, vol.12
, pp. 112
-
-
Windus, L.C.1
Glover, T.T.2
Avery, V.M.3
-
126
-
-
59849124087
-
Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer
-
Chu J.H., Yu S., Hayward S.W., Chan F.L. Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer. Prostate 2009, 69:428-442.
-
(2009)
Prostate
, vol.69
, pp. 428-442
-
-
Chu, J.H.1
Yu, S.2
Hayward, S.W.3
Chan, F.L.4
-
127
-
-
84881665292
-
Microfabricated polymeric vessel mimetics for 3-D cancer cell culture
-
Jaeger A.A., Das C.K., Morgan N.Y., Pursley R.H., McQueen P.G., Hall M.D., Pohida T.J., Gottesman M.M. Microfabricated polymeric vessel mimetics for 3-D cancer cell culture. Biomaterials 2013, 34:8301-8313.
-
(2013)
Biomaterials
, vol.34
, pp. 8301-8313
-
-
Jaeger, A.A.1
Das, C.K.2
Morgan, N.Y.3
Pursley, R.H.4
McQueen, P.G.5
Hall, M.D.6
Pohida, T.J.7
Gottesman, M.M.8
-
128
-
-
84883559642
-
In the beginning there were soft collagen-cell gels: towards better 3D connective tissue models?
-
Brown R.A. In the beginning there were soft collagen-cell gels: towards better 3D connective tissue models?. Exp. Cell Res. 2013, 319:2460-2469.
-
(2013)
Exp. Cell Res.
, vol.319
, pp. 2460-2469
-
-
Brown, R.A.1
-
129
-
-
33947518899
-
Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression
-
Barbolina M.V., Adley B.P., Ariztia E.V., Liu Y., Stack M.S. Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression. J. Biol. Chem. 2007, 282:4924-4931.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4924-4931
-
-
Barbolina, M.V.1
Adley, B.P.2
Ariztia, E.V.3
Liu, Y.4
Stack, M.S.5
-
130
-
-
66949150704
-
Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination
-
Moss N.M., Barbolina M.V., Liu Y., Sun L., Munshi H.G., Stack M.S. Ovarian cancer cell detachment and multicellular aggregate formation are regulated by membrane type 1 matrix metalloproteinase: a potential role in I.p. metastatic dissemination. Cancer Res. 2009, 69:7121-7129.
-
(2009)
Cancer Res.
, vol.69
, pp. 7121-7129
-
-
Moss, N.M.1
Barbolina, M.V.2
Liu, Y.3
Sun, L.4
Munshi, H.G.5
Stack, M.S.6
-
131
-
-
80053190887
-
Quantitative analysis of the effect of cancer invasiveness and collagen concentration on 3D matrix remodeling
-
Harjanto D., Maffei J.S., Zaman M.H. Quantitative analysis of the effect of cancer invasiveness and collagen concentration on 3D matrix remodeling. PLoS One 2011, 6:e24891.
-
(2011)
PLoS One
, vol.6
, pp. e24891
-
-
Harjanto, D.1
Maffei, J.S.2
Zaman, M.H.3
-
132
-
-
34648834682
-
The third dimension bridges the gap between cell culture and live tissue
-
Pampaloni F., Reynaud E.G., Stelzer E.H. The third dimension bridges the gap between cell culture and live tissue. Nat. Rev. Mol. Cell Biol. 2007, 8:839-845.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 839-845
-
-
Pampaloni, F.1
Reynaud, E.G.2
Stelzer, E.H.3
-
133
-
-
19644367664
-
Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering
-
Lutolf M.P., Hubbell J.A. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat. Biotechnol. 2005, 23:47-55.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 47-55
-
-
Lutolf, M.P.1
Hubbell, J.A.2
-
134
-
-
35848959463
-
Engineering tumors with 3D scaffolds
-
Fischbach C., Chen R., Matsumoto T., Schmelzle T., Brugge J.S., Polverini P.J., Mooney D.J. Engineering tumors with 3D scaffolds. Nat. Methods 2007, 4:855-860.
-
(2007)
Nat. Methods
, vol.4
, pp. 855-860
-
-
Fischbach, C.1
Chen, R.2
Matsumoto, T.3
Schmelzle, T.4
Brugge, J.S.5
Polverini, P.J.6
Mooney, D.J.7
-
135
-
-
77949313182
-
Artificial ECM: expanding the cell biology toolbox in 3D
-
Lutolf M.P. Artificial ECM: expanding the cell biology toolbox in 3D. Integr. Biol. 2009, 1:235-241.
-
(2009)
Integr. Biol.
, vol.1
, pp. 235-241
-
-
Lutolf, M.P.1
-
136
-
-
84862173770
-
Diagnostic microchip to assay 3D colony-growth potential of captured circulating tumor cells
-
Bichsel C.A., Gobaa S., Kobel S., Secondini C., Thalmann G.N., Cecchini M.G., Lutolf M.P. Diagnostic microchip to assay 3D colony-growth potential of captured circulating tumor cells. Lab Chip 2012, 12:2313-2316.
-
(2012)
Lab Chip
, vol.12
, pp. 2313-2316
-
-
Bichsel, C.A.1
Gobaa, S.2
Kobel, S.3
Secondini, C.4
Thalmann, G.N.5
Cecchini, M.G.6
Lutolf, M.P.7
-
137
-
-
84867142208
-
Recreating the tumor microenvironment in a bilayer, hyaluronic acid hydrogel construct for the growth of prostate cancer spheroids
-
Xu X., Gurski L.A., Zhang C., Harrington D.A., Farach-Carson M.C., Jia X. Recreating the tumor microenvironment in a bilayer, hyaluronic acid hydrogel construct for the growth of prostate cancer spheroids. Biomaterials 2012, 33:9049-9060.
-
(2012)
Biomaterials
, vol.33
, pp. 9049-9060
-
-
Xu, X.1
Gurski, L.A.2
Zhang, C.3
Harrington, D.A.4
Farach-Carson, M.C.5
Jia, X.6
-
138
-
-
69249230753
-
Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells
-
Gurski L.A., Jha A.K., Zhang C., Jia X., Farach-Carson M.C. Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells. Biomaterials 2009, 30:6076-6085.
-
(2009)
Biomaterials
, vol.30
, pp. 6076-6085
-
-
Gurski, L.A.1
Jha, A.K.2
Zhang, C.3
Jia, X.4
Farach-Carson, M.C.5
-
139
-
-
3843084007
-
Reticulated hyaluronan hydrogels: a model for examining cancer cell invasion in 3D
-
David L., Dulong V., Le Cerf D., Chauzy C., Norris V., Delpech B., Lamacz M., Vannier J.P. Reticulated hyaluronan hydrogels: a model for examining cancer cell invasion in 3D. Matrix Biol. 2004, 23:183-193.
-
(2004)
Matrix Biol.
, vol.23
, pp. 183-193
-
-
David, L.1
Dulong, V.2
Le Cerf, D.3
Chauzy, C.4
Norris, V.5
Delpech, B.6
Lamacz, M.7
Vannier, J.P.8
-
140
-
-
79953067209
-
Hyaluronic acid hydrogels for biomedical applications
-
Burdick J.A., Prestwich G.D. Hyaluronic acid hydrogels for biomedical applications. Adv. Mater. 2011, 23:H41-H56.
-
(2011)
Adv. Mater.
, vol.23
, pp. H41-H56
-
-
Burdick, J.A.1
Prestwich, G.D.2
-
141
-
-
58749094831
-
Use of hyaluronan-derived hydrogels for three-dimensional cell culture and tumor xenografts
-
10.14.1-10.14.21
-
Serban M.A., Scott A., Prestwich G.D. Use of hyaluronan-derived hydrogels for three-dimensional cell culture and tumor xenografts. Curr. Protoc. Cell Biol. 2008, 40:10.14.1-10.14.21.
-
(2008)
Curr. Protoc. Cell Biol.
, vol.40
-
-
Serban, M.A.1
Scott, A.2
Prestwich, G.D.3
-
142
-
-
34249880358
-
Tumor engineering: orthotopic cancer models in mice using cell-loaded, injectable, cross-linked hyaluronan-derived hydrogels
-
Liu Y., Shu X.Z., Prestwich G.D. Tumor engineering: orthotopic cancer models in mice using cell-loaded, injectable, cross-linked hyaluronan-derived hydrogels. Tissue Eng. 2007, 13:1091-1101.
-
(2007)
Tissue Eng.
, vol.13
, pp. 1091-1101
-
-
Liu, Y.1
Shu, X.Z.2
Prestwich, G.D.3
-
143
-
-
84869208688
-
Hyaluronan (HA) interacting proteins RHAMM and hyaluronidase impact prostate cancer cell behavior and invadopodia formation in 3D HA-based hydrogels
-
Gurski L.A., Xu X., Labrada L.N., Nguyen N.T., Xiao L., van Golen K.L., Jia X., Farach-Carson M.C. Hyaluronan (HA) interacting proteins RHAMM and hyaluronidase impact prostate cancer cell behavior and invadopodia formation in 3D HA-based hydrogels. PLoS One 2012, 7:e50075.
-
(2012)
PLoS One
, vol.7
, pp. e50075
-
-
Gurski, L.A.1
Xu, X.2
Labrada, L.N.3
Nguyen, N.T.4
Xiao, L.5
van Golen, K.L.6
Jia, X.7
Farach-Carson, M.C.8
-
144
-
-
50349086791
-
A paclitaxel-hyaluronan bioconjugate targeting ovarian cancer affords a potent in vivo therapeutic activity
-
Banzato A., Bobisse S., Rondina M., Renier D., Bettella F., Esposito G., Quintieri L., Melendez-Alafort L., Mazzi U., Zanovello P., Rosato A. A paclitaxel-hyaluronan bioconjugate targeting ovarian cancer affords a potent in vivo therapeutic activity. Clin. Cancer Res. 2008, 14:3598-3606.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3598-3606
-
-
Banzato, A.1
Bobisse, S.2
Rondina, M.3
Renier, D.4
Bettella, F.5
Esposito, G.6
Quintieri, L.7
Melendez-Alafort, L.8
Mazzi, U.9
Zanovello, P.10
Rosato, A.11
-
145
-
-
58849121351
-
Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement
-
Fischbach C., Kong H.J., Hsiong S.X., Evangelista M.B., Yuen W., Mooney D.J. Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:399-404.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 399-404
-
-
Fischbach, C.1
Kong, H.J.2
Hsiong, S.X.3
Evangelista, M.B.4
Yuen, W.5
Mooney, D.J.6
-
146
-
-
80055112089
-
Alginate hydrogels for three-dimensional organ culture of ovaries and oviducts
-
King S.M., Quartuccio S., Hilliard T.S., Inoue K., Burdette J.E. Alginate hydrogels for three-dimensional organ culture of ovaries and oviducts. J. Vis. Exp. 2011, 52:2804.
-
(2011)
J. Vis. Exp.
, vol.52
, pp. 2804
-
-
King, S.M.1
Quartuccio, S.2
Hilliard, T.S.3
Inoue, K.4
Burdette, J.E.5
-
147
-
-
84888637406
-
A biomimetic extracellular matrix for cartilage tissue engineering centered on photocurable gelatin, hyaluronic acid and chondroitin sulfate
-
Levett P.A., Melchels F.P., Schrobback K., Hutmacher D.W., Malda J., Klein T.J. A biomimetic extracellular matrix for cartilage tissue engineering centered on photocurable gelatin, hyaluronic acid and chondroitin sulfate. Acta Biomater. 2014, 10:214-223.
-
(2014)
Acta Biomater.
, vol.10
, pp. 214-223
-
-
Levett, P.A.1
Melchels, F.P.2
Schrobback, K.3
Hutmacher, D.W.4
Malda, J.5
Klein, T.J.6
-
148
-
-
77953025978
-
Cell-laden microengineered gelatin methacrylate hydrogels
-
Nichol J.W., Koshy S.T., Bae H., Hwang C.M., Yamanlar S., Khademhosseini A. Cell-laden microengineered gelatin methacrylate hydrogels. Biomaterials 2010, 31:5536-5544.
-
(2010)
Biomaterials
, vol.31
, pp. 5536-5544
-
-
Nichol, J.W.1
Koshy, S.T.2
Bae, H.3
Hwang, C.M.4
Yamanlar, S.5
Khademhosseini, A.6
-
149
-
-
0038481970
-
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited
-
Fidler I.J. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat. Rev. Cancer 2003, 3:453-458.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 453-458
-
-
Fidler, I.J.1
-
150
-
-
50549121134
-
The distribution of secondary growths in cancer of the breast
-
Paget S. The distribution of secondary growths in cancer of the breast. Lancet 1889, 133:571-573.
-
(1889)
Lancet
, vol.133
, pp. 571-573
-
-
Paget, S.1
-
151
-
-
33845881985
-
Stephen Paget and the 'seed and soil' theory of metastatic dissemination
-
Ribatti D., Mangialardi G., Vacca A. Stephen Paget and the 'seed and soil' theory of metastatic dissemination. Clin. Exp. Med. 2006, 6:145-149.
-
(2006)
Clin. Exp. Med.
, vol.6
, pp. 145-149
-
-
Ribatti, D.1
Mangialardi, G.2
Vacca, A.3
-
152
-
-
84858997017
-
Behavior of seeds and soil in the mechanism of metastasis: a deeper understanding
-
Mathot L., Stenninger J. Behavior of seeds and soil in the mechanism of metastasis: a deeper understanding. Cancer Sci. 2012, 103:626-631.
-
(2012)
Cancer Sci.
, vol.103
, pp. 626-631
-
-
Mathot, L.1
Stenninger, J.2
-
153
-
-
84879162428
-
Q&A: Mina Bissell on tumors as organs
-
Bissell M. Q&A: Mina Bissell on tumors as organs. Cancer Discov. 2013, 3:7.
-
(2013)
Cancer Discov.
, vol.3
, pp. 7
-
-
Bissell, M.1
-
154
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
156
-
-
33746417036
-
Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes
-
Bissell M.J., Kenny P.A., Radisky D.C. Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes. Cold Spring Harb. Symp. Quant. Biol. 2005, 70:343-356.
-
(2005)
Cold Spring Harb. Symp. Quant. Biol.
, vol.70
, pp. 343-356
-
-
Bissell, M.J.1
Kenny, P.A.2
Radisky, D.C.3
-
157
-
-
33644545381
-
Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
-
Overall C.M., Kleifeld O. Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nat. Rev. Cancer 2006, 6:227-239.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 227-239
-
-
Overall, C.M.1
Kleifeld, O.2
-
158
-
-
84904245364
-
Epithelial ovarian cancer experimental models
-
[Epub ahead of print]
-
Lengyel E., Burdette J.E., Kenny H.A., Matei D., Pilrose J., Haluska P., Nephew K.P., Hales D.B., Stack M.S. Epithelial ovarian cancer experimental models. Oncogene 2013, [Epub ahead of print].
-
(2013)
Oncogene
-
-
Lengyel, E.1
Burdette, J.E.2
Kenny, H.A.3
Matei, D.4
Pilrose, J.5
Haluska, P.6
Nephew, K.P.7
Hales, D.B.8
Stack, M.S.9
-
159
-
-
84877047730
-
A preclinical xenograft model of prostate cancer using human tumors
-
Lawrence M.G., Taylor R.A., Toivanen R., Pedersen J., Norden S., Pook D.W., Frydenberg M., Papargiris M.M., Niranjan B., Richards M.G., Wang H., Collins A.T., Maitland N.J., Risbridger G.P. A preclinical xenograft model of prostate cancer using human tumors. Nat. Protoc. 2013, 8:836-848.
-
(2013)
Nat. Protoc.
, vol.8
, pp. 836-848
-
-
Lawrence, M.G.1
Taylor, R.A.2
Toivanen, R.3
Pedersen, J.4
Norden, S.5
Pook, D.W.6
Frydenberg, M.7
Papargiris, M.M.8
Niranjan, B.9
Richards, M.G.10
Wang, H.11
Collins, A.T.12
Maitland, N.J.13
Risbridger, G.P.14
-
160
-
-
4344637470
-
Peritoneal inflammation - a microenvironment for epithelial ovarian cancer (EOC)
-
Freedman R.S., Deavers M., Liu J., Wang E. Peritoneal inflammation - a microenvironment for epithelial ovarian cancer (EOC). J. Transl. Med. 2004, 2:23.
-
(2004)
J. Transl. Med.
, vol.2
, pp. 23
-
-
Freedman, R.S.1
Deavers, M.2
Liu, J.3
Wang, E.4
-
161
-
-
19944426988
-
Peritoneal and subperitoneal stroma may facilitate regional spread of ovarian cancer
-
Wang E., Ngalame Y., Panelli M.C., Nguyen-Jackson H., Deavers M., Mueller P., Hu W., Savary C.A., Kobayashi R., Freedman R.S., Marincola F.M. Peritoneal and subperitoneal stroma may facilitate regional spread of ovarian cancer. Clin. Cancer Res. 2005, 11:113-122.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 113-122
-
-
Wang, E.1
Ngalame, Y.2
Panelli, M.C.3
Nguyen-Jackson, H.4
Deavers, M.5
Mueller, P.6
Hu, W.7
Savary, C.A.8
Kobayashi, R.9
Freedman, R.S.10
Marincola, F.M.11
-
162
-
-
9944223360
-
Correlation of tumor- and stromal-derived MT1-MMP expression with progression of human ovarian tumors in SCID mice
-
Drew A.F., Blick T.J., Lafleur M.A., Tim E.L., Robbie M.J., Rice G.E., Quinn M.A., Thompson E.W. Correlation of tumor- and stromal-derived MT1-MMP expression with progression of human ovarian tumors in SCID mice. Gynecol. Oncol. 2004, 95:437-448.
-
(2004)
Gynecol. Oncol.
, vol.95
, pp. 437-448
-
-
Drew, A.F.1
Blick, T.J.2
Lafleur, M.A.3
Tim, E.L.4
Robbie, M.J.5
Rice, G.E.6
Quinn, M.A.7
Thompson, E.W.8
-
164
-
-
72949119124
-
Integrins in cancer: biological implications and therapeutic opportunities
-
Desgrosellier J.S., Cheresh D.A. Integrins in cancer: biological implications and therapeutic opportunities. Nat. Rev. Cancer 2010, 10:9-22.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
165
-
-
81255188940
-
Tumor angiogenesis: molecular pathways and therapeutic targets
-
Weis S.M., Cheresh D.A. Tumor angiogenesis: molecular pathways and therapeutic targets. Nat. Med. 2011, 17:1359-1370.
-
(2011)
Nat. Med.
, vol.17
, pp. 1359-1370
-
-
Weis, S.M.1
Cheresh, D.A.2
-
166
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1995, 1:27-31.
-
(1995)
Nat. Med.
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
167
-
-
30744479430
-
Angiogenesis in life, disease and medicine
-
Carmeliet P. Angiogenesis in life, disease and medicine. Nature 2005, 438:932-936.
-
(2005)
Nature
, vol.438
, pp. 932-936
-
-
Carmeliet, P.1
-
168
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
Ferrara N., Kerbel R.S. Angiogenesis as a therapeutic target. Nature 2005, 438:967-974.
-
(2005)
Nature
, vol.438
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.S.2
-
169
-
-
84860661389
-
The peritoneal tumour microenvironment of high-grade serous ovarian cancer
-
Leinster D.A., Kulbe H., Everitt G., Thompson R., Perretti M., Gavins F.N., Cooper D., Gould D., Ennis D.P., Lockley M., McNeish I.A., Nourshargh S., Balkwill F.R. The peritoneal tumour microenvironment of high-grade serous ovarian cancer. J. Pathol. 2012, 227:136-145.
-
(2012)
J. Pathol.
, vol.227
, pp. 136-145
-
-
Leinster, D.A.1
Kulbe, H.2
Everitt, G.3
Thompson, R.4
Perretti, M.5
Gavins, F.N.6
Cooper, D.7
Gould, D.8
Ennis, D.P.9
Lockley, M.10
McNeish, I.A.11
Nourshargh, S.12
Balkwill, F.R.13
-
170
-
-
80052855899
-
Interleukin-6 as a therapeutic target in human ovarian cancer
-
Coward J., Kulbe H., Chakravarty P., Leader D., Vassileva V., Leinster D.A., Thompson R., Schioppa T., Nemeth J., Vermeulen J., Singh N., Avril N., Cummings J., Rexhepaj E., Jirstrom K., Gallagher W.M., Brennan D.J., McNeish I.A., Balkwill F.R. Interleukin-6 as a therapeutic target in human ovarian cancer. Clin. Cancer Res. 2011, 17:6083-6096.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 6083-6096
-
-
Coward, J.1
Kulbe, H.2
Chakravarty, P.3
Leader, D.4
Vassileva, V.5
Leinster, D.A.6
Thompson, R.7
Schioppa, T.8
Nemeth, J.9
Vermeulen, J.10
Singh, N.11
Avril, N.12
Cummings, J.13
Rexhepaj, E.14
Jirstrom, K.15
Gallagher, W.M.16
Brennan, D.J.17
McNeish, I.A.18
Balkwill, F.R.19
-
171
-
-
84855393623
-
A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment
-
Kulbe H., Chakravarty P., Leinster D.A., Charles K.A., Kwong J., Thompson R.G., Coward J.I., Schioppa T., Robinson S.C., Gallagher W.M., Galletta L., Salako M.A., Smyth J.F., Hagemann T., Brennan D.J., Bowtell D.D., Balkwill F.R. A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment. Cancer Res. 2012, 72:66-75.
-
(2012)
Cancer Res.
, vol.72
, pp. 66-75
-
-
Kulbe, H.1
Chakravarty, P.2
Leinster, D.A.3
Charles, K.A.4
Kwong, J.5
Thompson, R.G.6
Coward, J.I.7
Schioppa, T.8
Robinson, S.C.9
Gallagher, W.M.10
Galletta, L.11
Salako, M.A.12
Smyth, J.F.13
Hagemann, T.14
Brennan, D.J.15
Bowtell, D.D.16
Balkwill, F.R.17
-
172
-
-
84869886769
-
The role of interleukin-6 in gynaecological malignancies
-
Coward J.I., Kulbe H. The role of interleukin-6 in gynaecological malignancies. Cytokine Growth Factor Rev. 2012, 23:333-342.
-
(2012)
Cytokine Growth Factor Rev.
, vol.23
, pp. 333-342
-
-
Coward, J.I.1
Kulbe, H.2
-
173
-
-
0022891340
-
Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing
-
Dvorak H.F. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med. 1986, 315:1650-1659.
-
(1986)
N. Engl. J. Med.
, vol.315
, pp. 1650-1659
-
-
Dvorak, H.F.1
-
174
-
-
0033199807
-
Possible role of ovarian epithelial inflammation in ovarian cancer
-
Ness R.B., Cottreau C. Possible role of ovarian epithelial inflammation in ovarian cancer. J. Natl. Cancer Inst. 1999, 91:1459-1467.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 1459-1467
-
-
Ness, R.B.1
Cottreau, C.2
-
175
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
Joyce J.A., Pollard J.W. Microenvironmental regulation of metastasis. Nat. Rev. Cancer 2009, 9:239-252.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
176
-
-
84864102322
-
Design and fabrication of tubular scaffolds via direct writing in a melt electrospinning mode
-
Brown T.D., Slotosch A., Thibaudeau L., Taubenberger A., Loessner D., Vaquette C., Dalton P.D., Hutmacher D.W. Design and fabrication of tubular scaffolds via direct writing in a melt electrospinning mode. Biointerphases 2012, 7:13.
-
(2012)
Biointerphases
, vol.7
, pp. 13
-
-
Brown, T.D.1
Slotosch, A.2
Thibaudeau, L.3
Taubenberger, A.4
Loessner, D.5
Vaquette, C.6
Dalton, P.D.7
Hutmacher, D.W.8
-
177
-
-
80053169555
-
Ovarian cancer spheroids use myosin-generated force to clear the mesothelium
-
Iwanicki M.P., Davidowitz R.A., Ng M.R., Besser A., Muranen T., Merritt M., Danuser G., Ince T.A., Brugge J.S. Ovarian cancer spheroids use myosin-generated force to clear the mesothelium. Cancer Discov. 2011, 1:144-157.
-
(2011)
Cancer Discov.
, vol.1
, pp. 144-157
-
-
Iwanicki, M.P.1
Davidowitz, R.A.2
Ng, M.R.3
Besser, A.4
Muranen, T.5
Merritt, M.6
Danuser, G.7
Ince, T.A.8
Brugge, J.S.9
-
178
-
-
81255157465
-
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
-
Nieman K.M., Kenny H.A., Penicka C.V., Ladanyi A., Buell-Gutbrod R., Zillhardt M.R., Romero I.L., Carey M.S., Mills G.B., Hotamisligil G.S., Yamada S.D., Peter M.E., Gwin K., Lengyel E. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat. Med. 2011, 17:1498-1503.
-
(2011)
Nat. Med.
, vol.17
, pp. 1498-1503
-
-
Nieman, K.M.1
Kenny, H.A.2
Penicka, C.V.3
Ladanyi, A.4
Buell-Gutbrod, R.5
Zillhardt, M.R.6
Romero, I.L.7
Carey, M.S.8
Mills, G.B.9
Hotamisligil, G.S.10
Yamada, S.D.11
Peter, M.E.12
Gwin, K.13
Lengyel, E.14
-
179
-
-
41849105806
-
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin
-
Kenny H.A., Kaur S., Coussens L.M., Lengyel E. The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin. J. Clin. Invest. 2008, 118:1367-1379.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1367-1379
-
-
Kenny, H.A.1
Kaur, S.2
Coussens, L.M.3
Lengyel, E.4
-
180
-
-
34548274060
-
Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum
-
Kenny H.A., Krausz T., Yamada S.D., Lengyel E. Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum. Int. J. Cancer 2007, 121:1463-1472.
-
(2007)
Int. J. Cancer
, vol.121
, pp. 1463-1472
-
-
Kenny, H.A.1
Krausz, T.2
Yamada, S.D.3
Lengyel, E.4
-
181
-
-
84873039255
-
Mesenchymal stem cells enhance ovarian cancer cell infiltration through IL6 secretion in an amniochorionic membrane based 3D model
-
Touboul C., Lis R., Al Farsi H., Raynaud C.M., Warfa M., Althawadi H., Mery E., Mirshahi M., Rafii A. Mesenchymal stem cells enhance ovarian cancer cell infiltration through IL6 secretion in an amniochorionic membrane based 3D model. J. Transl. Med. 2013, 11:28.
-
(2013)
J. Transl. Med.
, vol.11
, pp. 28
-
-
Touboul, C.1
Lis, R.2
Al Farsi, H.3
Raynaud, C.M.4
Warfa, M.5
Althawadi, H.6
Mery, E.7
Mirshahi, M.8
Rafii, A.9
-
182
-
-
23844475131
-
Three-dimensional co-culture models to study prostate cancer growth, progression, and metastasis to bone
-
Wang R., Xu J., Juliette L., Castilleja A., Love J., Sung S.Y., Zhau H.E., Goodwin T.J., Chung L.W. Three-dimensional co-culture models to study prostate cancer growth, progression, and metastasis to bone. Semin. Cancer Biol. 2005, 15:353-364.
-
(2005)
Semin. Cancer Biol.
, vol.15
, pp. 353-364
-
-
Wang, R.1
Xu, J.2
Juliette, L.3
Castilleja, A.4
Love, J.5
Sung, S.Y.6
Zhau, H.E.7
Goodwin, T.J.8
Chung, L.W.9
-
183
-
-
84893718890
-
Signaling between tumor cells and the host bone marrow microenvironment
-
Kovacic N., Croucher P.I., McDonald M.M. Signaling between tumor cells and the host bone marrow microenvironment. Calcif. Tissue Int. 2014, 94:125-139.
-
(2014)
Calcif. Tissue Int.
, vol.94
, pp. 125-139
-
-
Kovacic, N.1
Croucher, P.I.2
McDonald, M.M.3
-
184
-
-
84899864278
-
RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization
-
Chu G.C., Zhau H.E., Wang R., Rogatko A., Feng X., Zayzafoon M., Liu Y., Farach-Carson M.C., You S., Kim J., Freeman M.R., Chung L.W. RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization. Endocr. Relat. Cancer 2014, 21:311-326.
-
(2014)
Endocr. Relat. Cancer
, vol.21
, pp. 311-326
-
-
Chu, G.C.1
Zhau, H.E.2
Wang, R.3
Rogatko, A.4
Feng, X.5
Zayzafoon, M.6
Liu, Y.7
Farach-Carson, M.C.8
You, S.9
Kim, J.10
Freeman, M.R.11
Chung, L.W.12
-
185
-
-
84871574173
-
Translation of a tumor microenvironment mimicking 3D tumor growth co-culture assay platform to high-content screening
-
Krausz E., de Hoogt R., Gustin E., Cornelissen F., Grand-Perret T., Janssen L., Vloemans N., Wuyts D., Frans S., Axel A., Peeters P.J., Hall B., Cik M. Translation of a tumor microenvironment mimicking 3D tumor growth co-culture assay platform to high-content screening. J. Biomol. Screen. 2013, 18:54-66.
-
(2013)
J. Biomol. Screen.
, vol.18
, pp. 54-66
-
-
Krausz, E.1
de Hoogt, R.2
Gustin, E.3
Cornelissen, F.4
Grand-Perret, T.5
Janssen, L.6
Vloemans, N.7
Wuyts, D.8
Frans, S.9
Axel, A.10
Peeters, P.J.11
Hall, B.12
Cik, M.13
-
186
-
-
81355147872
-
Three-dimensional cancer-bone metastasis model using ex-vivo co-cultures of live calvarial bones and cancer cells
-
Curtin P., Youm H., Salih E. Three-dimensional cancer-bone metastasis model using ex-vivo co-cultures of live calvarial bones and cancer cells. Biomaterials 2012, 33:1065-1078.
-
(2012)
Biomaterials
, vol.33
, pp. 1065-1078
-
-
Curtin, P.1
Youm, H.2
Salih, E.3
-
187
-
-
84884471160
-
Novel 3D co-culture model for epithelial-stromal cells interaction in prostate cancer
-
Fang X., Sittadjody S., Gyabaah K., Opara E.C., Balaji K.C. Novel 3D co-culture model for epithelial-stromal cells interaction in prostate cancer. PLoS One 2013, 8:e75187.
-
(2013)
PLoS One
, vol.8
, pp. e75187
-
-
Fang, X.1
Sittadjody, S.2
Gyabaah, K.3
Opara, E.C.4
Balaji, K.C.5
-
188
-
-
84876470676
-
Integrin alpha3beta1 regulates tumor cell responses to stromal cells and can function to suppress prostate cancer metastatic colonization
-
Varzavand A., Drake J.M., Svensson R.U., Herndon M.E., Zhou B., Henry M.D., Stipp C.S. Integrin alpha3beta1 regulates tumor cell responses to stromal cells and can function to suppress prostate cancer metastatic colonization. Clin. Exp. Metastasis 2013, 30:541-552.
-
(2013)
Clin. Exp. Metastasis
, vol.30
, pp. 541-552
-
-
Varzavand, A.1
Drake, J.M.2
Svensson, R.U.3
Herndon, M.E.4
Zhou, B.5
Henry, M.D.6
Stipp, C.S.7
-
189
-
-
84880433919
-
Modeling human tumor angiogenesis in a three-dimensional culture system
-
Seano G., Chiaverina G., Gagliardi P.A., di Blasio L., Sessa R., Bussolino F., Primo L. Modeling human tumor angiogenesis in a three-dimensional culture system. Blood 2013, 121:e129-e137.
-
(2013)
Blood
, vol.121
, pp. e129-e137
-
-
Seano, G.1
Chiaverina, G.2
Gagliardi, P.A.3
di Blasio, L.4
Sessa, R.5
Bussolino, F.6
Primo, L.7
-
190
-
-
84876750358
-
3D porous chitosan-alginate scaffolds: a new matrix for studying prostate cancer cell-lymphocyte interactions in vitro
-
Florczyk S.J., Liu G., Kievit F.M., Lewis A.M., Wu J.D., Zhang M. 3D porous chitosan-alginate scaffolds: a new matrix for studying prostate cancer cell-lymphocyte interactions in vitro. Adv. Health Mater. 2012, 1:590-599.
-
(2012)
Adv. Health Mater.
, vol.1
, pp. 590-599
-
-
Florczyk, S.J.1
Liu, G.2
Kievit, F.M.3
Lewis, A.M.4
Wu, J.D.5
Zhang, M.6
-
191
-
-
84869475828
-
Genetic polymorphisms in the human tissue kallikrein (KLK) locus and their implication in various malignant and non-malignant diseases
-
Batra J., O'Mara T., Patnala R., Lose F., Clements J.A. Genetic polymorphisms in the human tissue kallikrein (KLK) locus and their implication in various malignant and non-malignant diseases. Biol. Chem. 2012, 393:1365-1390.
-
(2012)
Biol. Chem.
, vol.393
, pp. 1365-1390
-
-
Batra, J.1
O'Mara, T.2
Patnala, R.3
Lose, F.4
Clements, J.A.5
-
192
-
-
77952918274
-
Genetic variation in microRNA networks: the implications for cancer research
-
Ryan B.M., Robles A.I., Harris C.C. Genetic variation in microRNA networks: the implications for cancer research. Nat. Rev. Cancer 2010, 10:389-402.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 389-402
-
-
Ryan, B.M.1
Robles, A.I.2
Harris, C.C.3
-
193
-
-
77955373045
-
Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus
-
Lawrence M.G., Lai J., Clements J.A. Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus. Endocr. Rev. 2010, 31:407-446.
-
(2010)
Endocr. Rev.
, vol.31
, pp. 407-446
-
-
Lawrence, M.G.1
Lai, J.2
Clements, J.A.3
-
194
-
-
79953253977
-
A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival
-
Batra J., Nagle C.M., O'Mara T., Higgins M., Dong Y., Tan O.L., Lose F., Skeie L.M., Srinivasan S., Bolton K.L., Song H., Ramus S.J., Gayther S.A., Pharoah P.D., Kedda M.A., Spurdle A.B., Clements J.A. A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival. BMC Cancer 2011, 11:119.
-
(2011)
BMC Cancer
, vol.11
, pp. 119
-
-
Batra, J.1
Nagle, C.M.2
O'Mara, T.3
Higgins, M.4
Dong, Y.5
Tan, O.L.6
Lose, F.7
Skeie, L.M.8
Srinivasan, S.9
Bolton, K.L.10
Song, H.11
Ramus, S.J.12
Gayther, S.A.13
Pharoah, P.D.14
Kedda, M.A.15
Spurdle, A.B.16
Clements, J.A.17
-
195
-
-
80051480296
-
Kallikrein-related peptidase 3 (KLK3/PSA) single nucleotide polymorphisms and ovarian cancer survival
-
O'Mara T.A., Nagle C.M., Batra J., Kedda M.A., Clements J.A., Spurdle A.B. Kallikrein-related peptidase 3 (KLK3/PSA) single nucleotide polymorphisms and ovarian cancer survival. Twin Res. Hum. Genet. 2011, 14:323-327.
-
(2011)
Twin Res. Hum. Genet.
, vol.14
, pp. 323-327
-
-
O'Mara, T.A.1
Nagle, C.M.2
Batra, J.3
Kedda, M.A.4
Clements, J.A.5
Spurdle, A.B.6
-
196
-
-
81755162937
-
Association between Prostinogen (KLK15) genetic variants and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data
-
Batra J., Lose F., O'Mara T., Marquart L., Stephens C., Alexander K., Srinivasan S., Eeles R.A., Easton D.F., Al Olama A.A., Kote-Jarai Z., Guy M., Muir K., Lophatananon A., Rahman A.A., Neal D.E., Hamdy F.C., Donovan J.L., Chambers S., Gardiner R.A., Aitken J., Yaxley J., Kedda M.A., Clements J.A., Spurdle A.B. Association between Prostinogen (KLK15) genetic variants and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data. PLoS One 2011, 6:e26527.
-
(2011)
PLoS One
, vol.6
, pp. e26527
-
-
Batra, J.1
Lose, F.2
O'Mara, T.3
Marquart, L.4
Stephens, C.5
Alexander, K.6
Srinivasan, S.7
Eeles, R.A.8
Easton, D.F.9
Al Olama, A.A.10
Kote-Jarai, Z.11
Guy, M.12
Muir, K.13
Lophatananon, A.14
Rahman, A.A.15
Neal, D.E.16
Hamdy, F.C.17
Donovan, J.L.18
Chambers, S.19
Gardiner, R.A.20
Aitken, J.21
Yaxley, J.22
Kedda, M.A.23
Clements, J.A.24
Spurdle, A.B.25
more..
-
197
-
-
84866060232
-
Genetic association of the KLK4 locus with risk of prostate cancer
-
Lose F., Srinivasan S., O'Mara T., Marquart L., Chambers S., Gardiner R.A., Aitken J.F., Spurdle A.B., Batra J., Clements J.A. Genetic association of the KLK4 locus with risk of prostate cancer. PLoS One 2012, 7:e44520.
-
(2012)
PLoS One
, vol.7
, pp. e44520
-
-
Lose, F.1
Srinivasan, S.2
O'Mara, T.3
Marquart, L.4
Chambers, S.5
Gardiner, R.A.6
Aitken, J.F.7
Spurdle, A.B.8
Batra, J.9
Clements, J.A.10
-
198
-
-
84859843770
-
The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness
-
Lose F., Lawrence M.G., Srinivasan S., O'Mara T., Marquart L., Chambers S., Gardiner R.A., Aitken J.F., Spurdle A.B., Batra J., Clements J.A. The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness. Biol. Chem. 2012, 393:403-412.
-
(2012)
Biol. Chem.
, vol.393
, pp. 403-412
-
-
Lose, F.1
Lawrence, M.G.2
Srinivasan, S.3
O'Mara, T.4
Marquart, L.5
Chambers, S.6
Gardiner, R.A.7
Aitken, J.F.8
Spurdle, A.B.9
Batra, J.10
Clements, J.A.11
-
199
-
-
47549102771
-
Kallikreins as microRNA targets: an in silico and experimental-based analysis
-
Chow T.F., Crow M., Earle T., El-Said H., Diamandis E.P., Yousef G.M. Kallikreins as microRNA targets: an in silico and experimental-based analysis. Biol. Chem. 2008, 389:731-738.
-
(2008)
Biol. Chem.
, vol.389
, pp. 731-738
-
-
Chow, T.F.1
Crow, M.2
Earle, T.3
El-Said, H.4
Diamandis, E.P.5
Yousef, G.M.6
-
200
-
-
84887160644
-
The role of microRNAs in the tumorigenesis of ovarian cancer
-
Di Leva G., Croce C.M. The role of microRNAs in the tumorigenesis of ovarian cancer. Front. Oncol. 2013, 3:153.
-
(2013)
Front. Oncol.
, vol.3
, pp. 153
-
-
Di Leva, G.1
Croce, C.M.2
-
201
-
-
84877832362
-
Identification of miRNA modulators to PARP inhibitor response
-
Neijenhuis S., Bajrami I., Miller R., Lord C.J., Ashworth A. Identification of miRNA modulators to PARP inhibitor response. DNA Repair 2013, 12:394-402.
-
(2013)
DNA Repair
, vol.12
, pp. 394-402
-
-
Neijenhuis, S.1
Bajrami, I.2
Miller, R.3
Lord, C.J.4
Ashworth, A.5
-
203
-
-
34548746977
-
MicroRNA signatures in human ovarian cancer
-
Iorio M.V., Visone R., Di Leva G., Donati V., Petrocca F., Casalini P., Taccioli C., Volinia S., Liu C.G., Alder H., Calin G.A., Menard S., Croce C.M. MicroRNA signatures in human ovarian cancer. Cancer Res. 2007, 67:8699-8707.
-
(2007)
Cancer Res.
, vol.67
, pp. 8699-8707
-
-
Iorio, M.V.1
Visone, R.2
Di Leva, G.3
Donati, V.4
Petrocca, F.5
Casalini, P.6
Taccioli, C.7
Volinia, S.8
Liu, C.G.9
Alder, H.10
Calin, G.A.11
Menard, S.12
Croce, C.M.13
-
204
-
-
77950860321
-
Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer
-
White N.M., Chow T.F., Mejia-Guerrero S., Diamandis M., Rofael Y., Faragalla H., Mankaruous M., Gabril M., Girgis A., Yousef G.M. Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer. Br. J. Cancer 2010, 102:1244-1253.
-
(2010)
Br. J. Cancer
, vol.102
, pp. 1244-1253
-
-
White, N.M.1
Chow, T.F.2
Mejia-Guerrero, S.3
Diamandis, M.4
Rofael, Y.5
Faragalla, H.6
Mankaruous, M.7
Gabril, M.8
Girgis, A.9
Yousef, G.M.10
-
205
-
-
34447132924
-
MicroRNA expression profiling in prostate cancer
-
Porkka K.P., Pfeiffer M.J., Waltering K.K., Vessella R.L., Tammela T.L., Visakorpi T. MicroRNA expression profiling in prostate cancer. Cancer Res. 2007, 67:6130-6135.
-
(2007)
Cancer Res.
, vol.67
, pp. 6130-6135
-
-
Porkka, K.P.1
Pfeiffer, M.J.2
Waltering, K.K.3
Vessella, R.L.4
Tammela, T.L.5
Visakorpi, T.6
-
206
-
-
38049100559
-
An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells
-
Shi X.B., Xue L., Yang J., Ma A.H., Zhao J., Xu M., Tepper C.G., Evans C.P., Kung H.J., deVere White R.W. An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:19983-19988.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 19983-19988
-
-
Shi, X.B.1
Xue, L.2
Yang, J.3
Ma, A.H.4
Zhao, J.5
Xu, M.6
Tepper, C.G.7
Evans, C.P.8
Kung, H.J.9
deVere White, R.W.10
-
207
-
-
84859880428
-
The miRNA-kallikrein axis of interaction: a new dimension in the pathogenesis of prostate cancer
-
White N.M., Youssef Y.M., Fendler A., Stephan C., Jung K., Yousef G.M. The miRNA-kallikrein axis of interaction: a new dimension in the pathogenesis of prostate cancer. Biol. Chem. 2012, 393:379-389.
-
(2012)
Biol. Chem.
, vol.393
, pp. 379-389
-
-
White, N.M.1
Youssef, Y.M.2
Fendler, A.3
Stephan, C.4
Jung, K.5
Yousef, G.M.6
-
208
-
-
67651002343
-
Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell
-
Sotiropoulou G., Pampalakis G., Lianidou E., Mourelatos Z. Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. RNA 2009, 15:1443-1461.
-
(2009)
RNA
, vol.15
, pp. 1443-1461
-
-
Sotiropoulou, G.1
Pampalakis, G.2
Lianidou, E.3
Mourelatos, Z.4
-
209
-
-
84871516015
-
MicroRNAs play a big role in regulating ovarian cancer-associated fibroblasts and the tumor microenvironment
-
Chou J., Werb Z. MicroRNAs play a big role in regulating ovarian cancer-associated fibroblasts and the tumor microenvironment. Cancer Discov. 2012, 2:1078-1080.
-
(2012)
Cancer Discov.
, vol.2
, pp. 1078-1080
-
-
Chou, J.1
Werb, Z.2
-
210
-
-
84871528926
-
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer
-
Mitra A.K., Zillhardt M., Hua Y., Tiwari P., Murmann A.E., Peter M.E., Lengyel E. MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer. Cancer Discov. 2012, 2:1100-1108.
-
(2012)
Cancer Discov.
, vol.2
, pp. 1100-1108
-
-
Mitra, A.K.1
Zillhardt, M.2
Hua, Y.3
Tiwari, P.4
Murmann, A.E.5
Peter, M.E.6
Lengyel, E.7
-
211
-
-
84887467125
-
Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment
-
Nishimura M., Jung E.J., Shah M.Y., Lu C., Spizzo R., Shimizu M., Han H.D., Ivan C., Rossi S., Zhang X., Nicoloso M.S., Wu S.Y., Almeida M.I., Bottsford-Miller J., Pecot C.V., Zand B., Matsuo K., Shahzad M.M., Jennings N.B., Rodriguez-Aguayo C., Lopez-Berestein G., Sood A.K., Calin G.A. Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment. Cancer Discov. 2013, 3:1302-1315.
-
(2013)
Cancer Discov.
, vol.3
, pp. 1302-1315
-
-
Nishimura, M.1
Jung, E.J.2
Shah, M.Y.3
Lu, C.4
Spizzo, R.5
Shimizu, M.6
Han, H.D.7
Ivan, C.8
Rossi, S.9
Zhang, X.10
Nicoloso, M.S.11
Wu, S.Y.12
Almeida, M.I.13
Bottsford-Miller, J.14
Pecot, C.V.15
Zand, B.16
Matsuo, K.17
Shahzad, M.M.18
Jennings, N.B.19
Rodriguez-Aguayo, C.20
Lopez-Berestein, G.21
Sood, A.K.22
Calin, G.A.23
more..
-
212
-
-
0034892043
-
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer
-
Schmalfeldt B., Prechtel D., Harting K., Spathe K., Rutke S., Konik E., Fridman R., Berger U., Schmitt M., Kuhn W., Lengyel E. Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer. Clin. Cancer Res. 2001, 7:2396-2404.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 2396-2404
-
-
Schmalfeldt, B.1
Prechtel, D.2
Harting, K.3
Spathe, K.4
Rutke, S.5
Konik, E.6
Fridman, R.7
Berger, U.8
Schmitt, M.9
Kuhn, W.10
Lengyel, E.11
-
213
-
-
22044445706
-
Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues
-
Riddick A.C., Shukla C.J., Pennington C.J., Bass R., Nuttall R.K., Hogan A., Sethia K.K., Ellis V., Collins A.T., Maitland N.J., Ball R.Y., Edwards D.R. Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues. Br. J. Cancer 2005, 92:2171-2180.
-
(2005)
Br. J. Cancer
, vol.92
, pp. 2171-2180
-
-
Riddick, A.C.1
Shukla, C.J.2
Pennington, C.J.3
Bass, R.4
Nuttall, R.K.5
Hogan, A.6
Sethia, K.K.7
Ellis, V.8
Collins, A.T.9
Maitland, N.J.10
Ball, R.Y.11
Edwards, D.R.12
-
214
-
-
34648815810
-
Emerging roles of proteases in tumour suppression
-
Lopez-Otin C., Matrisian L.M. Emerging roles of proteases in tumour suppression. Nat. Rev. Cancer 2007, 7:800-808.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 800-808
-
-
Lopez-Otin, C.1
Matrisian, L.M.2
-
215
-
-
0035188727
-
How matrix metalloproteinases regulate cell behavior
-
Sternlicht M.D., Werb Z. How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 2001, 17:463-516.
-
(2001)
Annu. Rev. Cell Dev. Biol.
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
216
-
-
0038713433
-
Dipeptidyl peptidase IV overexpression induces up-regulation of E-cadherin and tissue inhibitors of matrix metalloproteinases, resulting in decreased invasive potential in ovarian carcinoma cells
-
Kajiyama H., Kikkawa F., Khin E., Shibata K., Ino K., Mizutani S. Dipeptidyl peptidase IV overexpression induces up-regulation of E-cadherin and tissue inhibitors of matrix metalloproteinases, resulting in decreased invasive potential in ovarian carcinoma cells. Cancer Res. 2003, 63:2278-2283.
-
(2003)
Cancer Res.
, vol.63
, pp. 2278-2283
-
-
Kajiyama, H.1
Kikkawa, F.2
Khin, E.3
Shibata, K.4
Ino, K.5
Mizutani, S.6
-
217
-
-
13944249137
-
Dipeptidyl peptidase inhibits malignant phenotype of prostate cancer cells by blocking basic fibroblast growth factor signaling pathway
-
Wesley U.V., McGroarty M., Homoyouni A. Dipeptidyl peptidase inhibits malignant phenotype of prostate cancer cells by blocking basic fibroblast growth factor signaling pathway. Cancer Res. 2005, 65:1325-1334.
-
(2005)
Cancer Res.
, vol.65
, pp. 1325-1334
-
-
Wesley, U.V.1
McGroarty, M.2
Homoyouni, A.3
-
218
-
-
34249089882
-
Lentiviral vector neutral endopeptidase gene transfer suppresses prostate cancer tumor growth
-
Horiguchi A., Zheng R., Goodman O.B., Shen R., Guan H., Hersh L.B., Nanus D.M. Lentiviral vector neutral endopeptidase gene transfer suppresses prostate cancer tumor growth. Cancer Gene Ther. 2007, 14:583-589.
-
(2007)
Cancer Gene Ther.
, vol.14
, pp. 583-589
-
-
Horiguchi, A.1
Zheng, R.2
Goodman, O.B.3
Shen, R.4
Guan, H.5
Hersh, L.B.6
Nanus, D.M.7
-
219
-
-
13444283315
-
Novel role of prostate-specific membrane antigen in suppressing prostate cancer invasiveness
-
Ghosh A., Wang X., Klein E., Heston W.D. Novel role of prostate-specific membrane antigen in suppressing prostate cancer invasiveness. Cancer Res. 2005, 65:727-731.
-
(2005)
Cancer Res.
, vol.65
, pp. 727-731
-
-
Ghosh, A.1
Wang, X.2
Klein, E.3
Heston, W.D.4
-
220
-
-
84901975672
-
Proteomic and other analyses to determine the functional consequences of deregulated kallikrein-related peptidase (KLK) expression in prostate and ovarian cancer
-
Fuhrman-Luck R.A., Silva M.L., Dong Y., Irving-Rodgers H., Stoll T., Hastie M.L., Loessner D., Gorman J.J., Clements J.A. Proteomic and other analyses to determine the functional consequences of deregulated kallikrein-related peptidase (KLK) expression in prostate and ovarian cancer. Proteomics Clin. Appl. 2014, 8(5-6):403-415.
-
(2014)
Proteomics Clin. Appl.
, vol.8
, Issue.5-6
, pp. 403-415
-
-
Fuhrman-Luck, R.A.1
Silva, M.L.2
Dong, Y.3
Irving-Rodgers, H.4
Stoll, T.5
Hastie, M.L.6
Loessner, D.7
Gorman, J.J.8
Clements, J.A.9
-
221
-
-
28844509164
-
Proteolytically degradable hydrogels with a fluorogenic substrate for studies of cellular proteolytic activity and migration
-
Lee S.H., Miller J.S., Moon J.J., West J.L. Proteolytically degradable hydrogels with a fluorogenic substrate for studies of cellular proteolytic activity and migration. Biotechnol. Prog. 2005, 21:1736-1741.
-
(2005)
Biotechnol. Prog.
, vol.21
, pp. 1736-1741
-
-
Lee, S.H.1
Miller, J.S.2
Moon, J.J.3
West, J.L.4
-
222
-
-
3042783110
-
Tumor cell locomotion: differential dynamics of spontaneous and induced migration in a 3D collagen matrix
-
Niggemann B., Drell T.L.t., Joseph J., Weidt C., Lang K., Zaenker K.S., Entschladen F. Tumor cell locomotion: differential dynamics of spontaneous and induced migration in a 3D collagen matrix. Exp. Cell Res. 2004, 298:178-187.
-
(2004)
Exp. Cell Res.
, vol.298
, pp. 178-187
-
-
Niggemann, B.1
Drell, T.2
Joseph, J.3
Weidt, C.4
Lang, K.5
Zaenker, K.S.6
Entschladen, F.7
-
223
-
-
0037455576
-
Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis
-
Wolf K., Mazo I., Leung H., Engelke K., von Andrian U.H., Deryugina E.I., Strongin A.Y., Brocker E.B., Friedl P. Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J. Cell Biol. 2003, 160:267-277.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 267-277
-
-
Wolf, K.1
Mazo, I.2
Leung, H.3
Engelke, K.4
von Andrian, U.H.5
Deryugina, E.I.6
Strongin, A.Y.7
Brocker, E.B.8
Friedl, P.9
-
224
-
-
0042354574
-
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
-
Sahai E., Marshall C.J. Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat. Cell Biol. 2003, 5:711-719.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 711-719
-
-
Sahai, E.1
Marshall, C.J.2
-
225
-
-
78751682352
-
Elucidating the role of matrix stiffness in 3D cell migration and remodeling
-
Ehrbar M., Sala A., Lienemann P., Ranga A., Mosiewicz K., Bittermann A., Rizzi S.C., Weber F.E., Lutolf M.P. Elucidating the role of matrix stiffness in 3D cell migration and remodeling. Biophys. J. 2011, 100:284-293.
-
(2011)
Biophys. J.
, vol.100
, pp. 284-293
-
-
Ehrbar, M.1
Sala, A.2
Lienemann, P.3
Ranga, A.4
Mosiewicz, K.5
Bittermann, A.6
Rizzi, S.C.7
Weber, F.E.8
Lutolf, M.P.9
-
226
-
-
79953163995
-
Proteolytic networks in cancer
-
Mason S.D., Joyce J.A. Proteolytic networks in cancer. Trends Cell Biol. 2011, 21:228-237.
-
(2011)
Trends Cell Biol.
, vol.21
, pp. 228-237
-
-
Mason, S.D.1
Joyce, J.A.2
-
227
-
-
58149288221
-
Direct visualization of protease activity on cells migrating in three-dimensions
-
Packard B.Z., Artym V.V., Komoriya A., Yamada K.M. Direct visualization of protease activity on cells migrating in three-dimensions. Matrix Biol. 2009, 28:3-10.
-
(2009)
Matrix Biol.
, vol.28
, pp. 3-10
-
-
Packard, B.Z.1
Artym, V.V.2
Komoriya, A.3
Yamada, K.M.4
-
228
-
-
84898001922
-
Tumor-targeted prodrug ICT2588 demonstrates therapeutic activity against solid tumors and reduced potential for cardiovascular toxicity
-
Gill J.H., Loadman P.M., Shnyder S.D., Cooper P., Atkinson J.M., Ribeiro Morais G., Patterson L.H., Falconer R.A. Tumor-targeted prodrug ICT2588 demonstrates therapeutic activity against solid tumors and reduced potential for cardiovascular toxicity. Mol. Pharm. 2014, 11(4):1294-1300.
-
(2014)
Mol. Pharm.
, vol.11
, Issue.4
, pp. 1294-1300
-
-
Gill, J.H.1
Loadman, P.M.2
Shnyder, S.D.3
Cooper, P.4
Atkinson, J.M.5
Ribeiro Morais, G.6
Patterson, L.H.7
Falconer, R.A.8
-
230
-
-
15744371624
-
Bone microenvironment modulates expression and activity of cathepsin B in prostate cancer
-
Podgorski I., Linebaugh B.E., Sameni M., Jedeszko C., Bhagat S., Cher M.L., Sloane B.F. Bone microenvironment modulates expression and activity of cathepsin B in prostate cancer. Neoplasia 2005, 7:207-223.
-
(2005)
Neoplasia
, vol.7
, pp. 207-223
-
-
Podgorski, I.1
Linebaugh, B.E.2
Sameni, M.3
Jedeszko, C.4
Bhagat, S.5
Cher, M.L.6
Sloane, B.F.7
-
231
-
-
62449181023
-
Imaging and quantifying the dynamics of tumor-associated proteolysis
-
Sameni M., Cavallo-Medved D., Dosescu J., Jedeszko C., Moin K., Mullins S.R., Olive M.B., Rudy D., Sloane B.F. Imaging and quantifying the dynamics of tumor-associated proteolysis. Clin. Exp. Metastasis 2009, 26:299-309.
-
(2009)
Clin. Exp. Metastasis
, vol.26
, pp. 299-309
-
-
Sameni, M.1
Cavallo-Medved, D.2
Dosescu, J.3
Jedeszko, C.4
Moin, K.5
Mullins, S.R.6
Olive, M.B.7
Rudy, D.8
Sloane, B.F.9
-
232
-
-
84857824501
-
MAME models for 4D live-cell imaging of tumor: microenvironment interactions that impact malignant progression
-
3661
-
Sameni M., Anbalagan A., Olive M.B., Moin K., Mattingly R.R., Sloane B.F. MAME models for 4D live-cell imaging of tumor: microenvironment interactions that impact malignant progression. J. Vis. Exp. 2012, 60. (pii: 3661).
-
(2012)
J. Vis. Exp.
, vol.60
-
-
Sameni, M.1
Anbalagan, A.2
Olive, M.B.3
Moin, K.4
Mattingly, R.R.5
Sloane, B.F.6
-
233
-
-
0037965624
-
Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics
-
Lutolf M.P., Lauer-Fields J.L., Schmoekel H.G., Metters A.T., Weber F.E., Fields G.B., Hubbell J.A. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:5413-5418.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 5413-5418
-
-
Lutolf, M.P.1
Lauer-Fields, J.L.2
Schmoekel, H.G.3
Metters, A.T.4
Weber, F.E.5
Fields, G.B.6
Hubbell, J.A.7
-
234
-
-
34247112791
-
Poly(ethylene glycol) hydrogels conjugated with a collagenase-sensitive fluorogenic substrate to visualize collagenase activity during three-dimensional cell migration
-
Lee S.H., Moon J.J., Miller J.S., West J.L. Poly(ethylene glycol) hydrogels conjugated with a collagenase-sensitive fluorogenic substrate to visualize collagenase activity during three-dimensional cell migration. Biomaterials 2007, 28:3163-3170.
-
(2007)
Biomaterials
, vol.28
, pp. 3163-3170
-
-
Lee, S.H.1
Moon, J.J.2
Miller, J.S.3
West, J.L.4
-
235
-
-
68849096820
-
Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments
-
DeForest C.A., Polizzotti B.D., Anseth K.S. Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments. Nat. Mater. 2009, 8:659-664.
-
(2009)
Nat. Mater.
, vol.8
, pp. 659-664
-
-
DeForest, C.A.1
Polizzotti, B.D.2
Anseth, K.S.3
-
236
-
-
84880510300
-
Direct measurement of matrix metalloproteinase activity in 3D cellular microenvironments using a fluorogenic peptide substrate
-
Leight J.L., Alge D.L., Maier A.J., Anseth K.S. Direct measurement of matrix metalloproteinase activity in 3D cellular microenvironments using a fluorogenic peptide substrate. Biomaterials 2013, 34:7344-7352.
-
(2013)
Biomaterials
, vol.34
, pp. 7344-7352
-
-
Leight, J.L.1
Alge, D.L.2
Maier, A.J.3
Anseth, K.S.4
-
237
-
-
0035070418
-
Tumor cell invasion of model 3-dimensional matrices: demonstration of migratory pathways, collagen disruption, and intercellular cooperation
-
Horino K., Kindezelskii A.L., Elner V.M., Hughes B.A., Petty H.R. Tumor cell invasion of model 3-dimensional matrices: demonstration of migratory pathways, collagen disruption, and intercellular cooperation. FASEB J. 2001, 15:932-939.
-
(2001)
FASEB J.
, vol.15
, pp. 932-939
-
-
Horino, K.1
Kindezelskii, A.L.2
Elner, V.M.3
Hughes, B.A.4
Petty, H.R.5
-
238
-
-
62449216585
-
Mapping proteolytic cancer cell-extracellular matrix interfaces
-
Wolf K., Friedl P. Mapping proteolytic cancer cell-extracellular matrix interfaces. Clin. Exp. Metastasis 2009, 26:289-298.
-
(2009)
Clin. Exp. Metastasis
, vol.26
, pp. 289-298
-
-
Wolf, K.1
Friedl, P.2
-
239
-
-
33744487875
-
Molecular imaging in cancer
-
Weissleder R. Molecular imaging in cancer. Science 2006, 312:1168-1171.
-
(2006)
Science
, vol.312
, pp. 1168-1171
-
-
Weissleder, R.1
-
240
-
-
84865660759
-
Combined in vivo molecular and anatomic imaging for detection of ovarian carcinoma-associated protease activity and integrin expression in mice
-
Hensley H.H., Roder N.A., O'Brien S.W., Bickel L.E., Xiao F., Litwin S., Connolly D.C. Combined in vivo molecular and anatomic imaging for detection of ovarian carcinoma-associated protease activity and integrin expression in mice. Neoplasia 2012, 14:451-462.
-
(2012)
Neoplasia
, vol.14
, pp. 451-462
-
-
Hensley, H.H.1
Roder, N.A.2
O'Brien, S.W.3
Bickel, L.E.4
Xiao, F.5
Litwin, S.6
Connolly, D.C.7
-
241
-
-
84855428544
-
New approaches for dissecting protease functions to improve probe development and drug discovery
-
Deu E., Verdoes M., Bogyo M. New approaches for dissecting protease functions to improve probe development and drug discovery. Nat. Struct. Mol. Biol. 2012, 19:9-16.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 9-16
-
-
Deu, E.1
Verdoes, M.2
Bogyo, M.3
-
242
-
-
84885112885
-
An improved quenched fluorescent probe for imaging of cysteine cathepsin activity
-
Verdoes M., Oresic Bender K., Segal E., van der Linden W.A., Syed S., Withana N.P., Sanman L.E., Bogyo M. An improved quenched fluorescent probe for imaging of cysteine cathepsin activity. J. Am. Chem. Soc. 2013, 135:14726-14730.
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 14726-14730
-
-
Verdoes, M.1
Oresic Bender, K.2
Segal, E.3
van der Linden, W.A.4
Syed, S.5
Withana, N.P.6
Sanman, L.E.7
Bogyo, M.8
-
243
-
-
84869389974
-
Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins
-
Mullins S.R., Sameni M., Blum G., Bogyo M., Sloane B., Moin K. Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins. Biol. Chem. 2012, 393:1405-1416.
-
(2012)
Biol. Chem.
, vol.393
, pp. 1405-1416
-
-
Mullins, S.R.1
Sameni, M.2
Blum, G.3
Bogyo, M.4
Sloane, B.5
Moin, K.6
-
244
-
-
84865021333
-
Cathepsin S cannibalism of cathepsin K as a mechanism to reduce type I collagen degradation
-
Barry Z.T., Platt M.O. Cathepsin S cannibalism of cathepsin K as a mechanism to reduce type I collagen degradation. J. Biol. Chem. 2012, 287:27723-27730.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 27723-27730
-
-
Barry, Z.T.1
Platt, M.O.2
-
245
-
-
84878102947
-
A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice
-
Godinat A., Park H.M., Miller S.C., Cheng K., Hanahan D., Sanman L.E., Bogyo M., Yu A., Nikitin G.F., Stahl A., Dubikovskaya E.A. A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice. ACS Chem. Biol. 2013, 8:987-999.
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 987-999
-
-
Godinat, A.1
Park, H.M.2
Miller, S.C.3
Cheng, K.4
Hanahan, D.5
Sanman, L.E.6
Bogyo, M.7
Yu, A.8
Nikitin, G.F.9
Stahl, A.10
Dubikovskaya, E.A.11
-
246
-
-
67649547851
-
Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4
-
Swedberg J.E., Nigon L.V., Reid J.C., de Veer S.J., Walpole C.M., Stephens C.R., Walsh T.P., Takayama T.K., Hooper J.D., Clements J.A., Buckle A.M., Harris J.M. Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4. Chem. Biol. 2009, 16:633-643.
-
(2009)
Chem. Biol.
, vol.16
, pp. 633-643
-
-
Swedberg, J.E.1
Nigon, L.V.2
Reid, J.C.3
de Veer, S.J.4
Walpole, C.M.5
Stephens, C.R.6
Walsh, T.P.7
Takayama, T.K.8
Hooper, J.D.9
Clements, J.A.10
Buckle, A.M.11
Harris, J.M.12
-
247
-
-
84874510596
-
Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment
-
Dong Y., Stephens C., Walpole C., Swedberg J.E., Boyle G.M., Parsons P.G., McGuckin M.A., Harris J.M., Clements J.A. Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment. PLoS One 2013, 8:e57056.
-
(2013)
PLoS One
, vol.8
, pp. e57056
-
-
Dong, Y.1
Stephens, C.2
Walpole, C.3
Swedberg, J.E.4
Boyle, G.M.5
Parsons, P.G.6
McGuckin, M.A.7
Harris, J.M.8
Clements, J.A.9
-
248
-
-
81755163602
-
Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance
-
Gillet J.P., Calcagno A.M., Varma S., Marino M., Green L.J., Vora M.I., Patel C., Orina J.N., Eliseeva T.A., Singal V., Padmanabhan R., Davidson B., Ganapathi R., Sood A.K., Rueda B.R., Ambudkar S.V., Gottesman M.M. Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:18708-18713.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 18708-18713
-
-
Gillet, J.P.1
Calcagno, A.M.2
Varma, S.3
Marino, M.4
Green, L.J.5
Vora, M.I.6
Patel, C.7
Orina, J.N.8
Eliseeva, T.A.9
Singal, V.10
Padmanabhan, R.11
Davidson, B.12
Ganapathi, R.13
Sood, A.K.14
Rueda, B.R.15
Ambudkar, S.V.16
Gottesman, M.M.17
-
249
-
-
84880291315
-
Evaluating cell lines as tumour models by comparison of genomic profiles
-
Domcke S., Sinha R., Levine D.A., Sander C., Schultz N. Evaluating cell lines as tumour models by comparison of genomic profiles. Nat. Commun. 2013, 4:2126.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2126
-
-
Domcke, S.1
Sinha, R.2
Levine, D.A.3
Sander, C.4
Schultz, N.5
-
250
-
-
16544380146
-
The use of 3-D cultures for high-throughput screening: the multicellular spheroid model
-
Kunz-Schughart L.A., Freyer J.P., Hofstaedter F., Ebner R. The use of 3-D cultures for high-throughput screening: the multicellular spheroid model. J. Biomol. Screen. 2004, 9:273-285.
-
(2004)
J. Biomol. Screen.
, vol.9
, pp. 273-285
-
-
Kunz-Schughart, L.A.1
Freyer, J.P.2
Hofstaedter, F.3
Ebner, R.4
-
251
-
-
68549104172
-
Three-dimensional tissue models for drug discovery and toxicology
-
Pampaloni F., Stelzer E.H., Masotti A. Three-dimensional tissue models for drug discovery and toxicology. Recent Pat. Biotechnol. 2009, 3:103-117.
-
(2009)
Recent Pat. Biotechnol.
, vol.3
, pp. 103-117
-
-
Pampaloni, F.1
Stelzer, E.H.2
Masotti, A.3
-
252
-
-
77953916745
-
Multicellular tumor spheroids: an underestimated tool is catching up again
-
Hirschhaeuser F., Menne H., Dittfeld C., West J., Mueller-Klieser W., Kunz-Schughart L.A. Multicellular tumor spheroids: an underestimated tool is catching up again. J. Biotechnol. 2010, 148:3-15.
-
(2010)
J. Biotechnol.
, vol.148
, pp. 3-15
-
-
Hirschhaeuser, F.1
Menne, H.2
Dittfeld, C.3
West, J.4
Mueller-Klieser, W.5
Kunz-Schughart, L.A.6
-
253
-
-
84877255483
-
A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro
-
Myungjin Lee J., Mhawech-Fauceglia P., Lee N., Cristina Parsanian L., Gail Lin Y., Andrew Gayther S., Lawrenson K. A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro. Lab. Invest. 2013, 93:528-542.
-
(2013)
Lab. Invest.
, vol.93
, pp. 528-542
-
-
Myungjin Lee, J.1
Mhawech-Fauceglia, P.2
Lee, N.3
Cristina Parsanian, L.4
Gail Lin, Y.5
Andrew Gayther, S.6
Lawrenson, K.7
-
254
-
-
38349104537
-
Three-dimensional cellular microarray for high-throughput toxicology assays
-
Lee M.Y., Kumar R.A., Sukumaran S.M., Hogg M.G., Clark D.S., Dordick J.S. Three-dimensional cellular microarray for high-throughput toxicology assays. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:59-63.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 59-63
-
-
Lee, M.Y.1
Kumar, R.A.2
Sukumaran, S.M.3
Hogg, M.G.4
Clark, D.S.5
Dordick, J.S.6
-
255
-
-
84892406857
-
Development of a high-throughput three-dimensional invasion assay for anti-cancer drug discovery
-
Evensen N.A., Li J., Yang J., Yu X., Sampson N.S., Zucker S., Cao J. Development of a high-throughput three-dimensional invasion assay for anti-cancer drug discovery. PLoS One 2013, 8:e82811.
-
(2013)
PLoS One
, vol.8
, pp. e82811
-
-
Evensen, N.A.1
Li, J.2
Yang, J.3
Yu, X.4
Sampson, N.S.5
Zucker, S.6
Cao, J.7
-
256
-
-
42549096978
-
Magnetic resonance imaging for detection and determination of tumor volume in a genetically engineered mouse model of ovarian cancer
-
Hensley H., Quinn B.A., Wolf R.L., Litwin S.L., Mabuchi S., Williams S.J., Williams C., Hamilton T.C., Connolly D.C. Magnetic resonance imaging for detection and determination of tumor volume in a genetically engineered mouse model of ovarian cancer. Cancer Biol. Ther. 2007, 6:1717-1725.
-
(2007)
Cancer Biol. Ther.
, vol.6
, pp. 1717-1725
-
-
Hensley, H.1
Quinn, B.A.2
Wolf, R.L.3
Litwin, S.L.4
Mabuchi, S.5
Williams, S.J.6
Williams, C.7
Hamilton, T.C.8
Connolly, D.C.9
-
257
-
-
84887999723
-
Modeling high-grade serous carcinoma: how converging insights into pathogenesis and genetics are driving better experimental platforms
-
Jones P.M., Drapkin R. Modeling high-grade serous carcinoma: how converging insights into pathogenesis and genetics are driving better experimental platforms. Front. Oncol. 2013, 3:217.
-
(2013)
Front. Oncol.
, vol.3
, pp. 217
-
-
Jones, P.M.1
Drapkin, R.2
-
258
-
-
0037302815
-
Animal models of bone metastasis
-
Rosol T.J., Tannehill-Gregg S.H., LeRoy B.E., Mandl S., Contag C.H. Animal models of bone metastasis. Cancer 2003, 97:748-757.
-
(2003)
Cancer
, vol.97
, pp. 748-757
-
-
Rosol, T.J.1
Tannehill-Gregg, S.H.2
LeRoy, B.E.3
Mandl, S.4
Contag, C.H.5
-
259
-
-
66849128197
-
Xenograft and transgenic mouse models of epithelial ovarian cancer and non-invasive imaging modalities to monitor ovarian tumor growth in situ: applications in evaluating novel therapeutic agents
-
14.12.1-14.12.26
-
Connolly D.C., Hensley H.H. Xenograft and transgenic mouse models of epithelial ovarian cancer and non-invasive imaging modalities to monitor ovarian tumor growth in situ: applications in evaluating novel therapeutic agents. Curr. Protoc. Pharmacol. 2009, 45:14.12.1-14.12.26.
-
(2009)
Curr. Protoc. Pharmacol.
, vol.45
-
-
Connolly, D.C.1
Hensley, H.H.2
-
260
-
-
84892380200
-
Patient-derived xenograft models to improve targeted therapy in epithelial ovarian cancer treatment
-
Scott C.L., Becker M.A., Haluska P., Samimi G. Patient-derived xenograft models to improve targeted therapy in epithelial ovarian cancer treatment. Front. Oncol. 2013, 3:295.
-
(2013)
Front. Oncol.
, vol.3
, pp. 295
-
-
Scott, C.L.1
Becker, M.A.2
Haluska, P.3
Samimi, G.4
-
261
-
-
1342288971
-
Opinion: comparative biology of mouse versus human cells: modelling human cancer in mice
-
Rangarajan A., Weinberg R.A. Opinion: comparative biology of mouse versus human cells: modelling human cancer in mice. Nat. Rev. Cancer 2003, 3:952-959.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 952-959
-
-
Rangarajan, A.1
Weinberg, R.A.2
-
262
-
-
84873378629
-
Can bone tissue engineering contribute to therapy concepts after resection of musculoskeletal sarcoma?
-
Holzapfel B.M., Chhaya M.P., Melchels F.P., Holzapfel N.P., Prodinger P.M., von Eisenhart-Rothe R., van Griensven M., Schantz J.T., Rudert M., Hutmacher D.W. Can bone tissue engineering contribute to therapy concepts after resection of musculoskeletal sarcoma?. Sarcoma 2013, 2013:153640.
-
(2013)
Sarcoma
, vol.2013
, pp. 153640
-
-
Holzapfel, B.M.1
Chhaya, M.P.2
Melchels, F.P.3
Holzapfel, N.P.4
Prodinger, P.M.5
von Eisenhart-Rothe, R.6
van Griensven, M.7
Schantz, J.T.8
Rudert, M.9
Hutmacher, D.W.10
-
263
-
-
84878261247
-
The hen as a model of ovarian cancer
-
Johnson P.A., Giles J.R. The hen as a model of ovarian cancer. Nat. Rev. Cancer 2013, 13:432-436.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 432-436
-
-
Johnson, P.A.1
Giles, J.R.2
-
264
-
-
84878082830
-
Gelatin nanoparticles as gene carriers for transgenic chicken applications
-
Tseng C.L., Peng C.L., Huang J.Y., Chen J.C., Lin F.H. Gelatin nanoparticles as gene carriers for transgenic chicken applications. J. Biomater. Appl. 2013, 27:1055-1065.
-
(2013)
J. Biomater. Appl.
, vol.27
, pp. 1055-1065
-
-
Tseng, C.L.1
Peng, C.L.2
Huang, J.Y.3
Chen, J.C.4
Lin, F.H.5
-
265
-
-
18344380440
-
Ovarian cancer metastasis: integrating insights from disparate model organisms
-
Naora H., Montell D.J. Ovarian cancer metastasis: integrating insights from disparate model organisms. Nat. Rev. Cancer 2005, 5:355-366.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 355-366
-
-
Naora, H.1
Montell, D.J.2
-
266
-
-
10344219949
-
Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer
-
Shaw T.J., Senterman M.K., Dawson K., Crane C.A., Vanderhyden B.C. Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer. Mol. Ther. 2004, 10:1032-1042.
-
(2004)
Mol. Ther.
, vol.10
, pp. 1032-1042
-
-
Shaw, T.J.1
Senterman, M.K.2
Dawson, K.3
Crane, C.A.4
Vanderhyden, B.C.5
-
267
-
-
70449338171
-
Ovarian cancer update: lessons from morphology, molecules, and mice
-
Cho K.R. Ovarian cancer update: lessons from morphology, molecules, and mice. Arch. Pathol. Lab. Med. 2009, 133:1775-1781.
-
(2009)
Arch. Pathol. Lab. Med.
, vol.133
, pp. 1775-1781
-
-
Cho, K.R.1
-
268
-
-
0036463949
-
Induction of ovarian cancer by defined multiple genetic changes in a mouse model system
-
Orsulic S., Li Y., Soslow R.A., Vitale-Cross L.A., Gutkind J.S., Varmus H.E. Induction of ovarian cancer by defined multiple genetic changes in a mouse model system. Cancer Cell 2002, 1:53-62.
-
(2002)
Cancer Cell
, vol.1
, pp. 53-62
-
-
Orsulic, S.1
Li, Y.2
Soslow, R.A.3
Vitale-Cross, L.A.4
Gutkind, J.S.5
Varmus, H.E.6
-
269
-
-
84901276587
-
Genetically engineered mouse models for epithelial ovarian cancer: are we there yet?
-
Howell V.M. Genetically engineered mouse models for epithelial ovarian cancer: are we there yet?. Semin. Cell Dev. Biol. 2014, 27C:106-117.
-
(2014)
Semin. Cell Dev. Biol.
, vol.27 C
, pp. 106-117
-
-
Howell, V.M.1
-
270
-
-
58849134940
-
Niche-dependent tumorigenic capacity of malignant ovarian ascites-derived cancer cell subpopulations
-
Katz E., Skorecki K., Tzukerman M. Niche-dependent tumorigenic capacity of malignant ovarian ascites-derived cancer cell subpopulations. Clin. Cancer Res. 2009, 15:70-80.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 70-80
-
-
Katz, E.1
Skorecki, K.2
Tzukerman, M.3
-
271
-
-
0036604237
-
Establishment and characterization of osseous prostate cancer models: intra-tibial injection of human prostate cancer cells
-
Corey E., Quinn J.E., Bladou F., Brown L.G., Roudier M.P., Brown J.M., Buhler K.R., Vessella R.L. Establishment and characterization of osseous prostate cancer models: intra-tibial injection of human prostate cancer cells. Prostate 2002, 52:20-33.
-
(2002)
Prostate
, vol.52
, pp. 20-33
-
-
Corey, E.1
Quinn, J.E.2
Bladou, F.3
Brown, L.G.4
Roudier, M.P.5
Brown, J.M.6
Buhler, K.R.7
Vessella, R.L.8
-
272
-
-
12444308202
-
Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts
-
Fizazi K., Yang J., Peleg S., Sikes C.R., Kreimann E.L., Daliani D., Olive M., Raymond K.A., Janus T.J., Logothetis C.J., Karsenty G., Navone N.M. Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts. Clin. Cancer Res. 2003, 9:2587-2597.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 2587-2597
-
-
Fizazi, K.1
Yang, J.2
Peleg, S.3
Sikes, C.R.4
Kreimann, E.L.5
Daliani, D.6
Olive, M.7
Raymond, K.A.8
Janus, T.J.9
Logothetis, C.J.10
Karsenty, G.11
Navone, N.M.12
-
273
-
-
0037728969
-
Osteoprotegerin/osteoclastogenesis inhibitory factor decreases human prostate cancer burden in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice
-
Yonou H., Kanomata N., Goya M., Kamijo T., Yokose T., Hasebe T., Nagai K., Hatano T., Ogawa Y., Ochiai A. Osteoprotegerin/osteoclastogenesis inhibitory factor decreases human prostate cancer burden in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice. Cancer Res. 2003, 63:2096-2102.
-
(2003)
Cancer Res.
, vol.63
, pp. 2096-2102
-
-
Yonou, H.1
Kanomata, N.2
Goya, M.3
Kamijo, T.4
Yokose, T.5
Hasebe, T.6
Nagai, K.7
Hatano, T.8
Ogawa, Y.9
Ochiai, A.10
-
274
-
-
1542317670
-
Intraosseous growth of human prostate cancer in implanted adult human bone: relationship of prostate cancer cells to osteoclasts in osteoblastic metastatic lesions
-
Yonou H., Ochiai A., Goya M., Kanomata N., Hokama S., Morozumi M., Sugaya K., Hatano T., Ogawa Y. Intraosseous growth of human prostate cancer in implanted adult human bone: relationship of prostate cancer cells to osteoclasts in osteoblastic metastatic lesions. Prostate 2004, 58:406-413.
-
(2004)
Prostate
, vol.58
, pp. 406-413
-
-
Yonou, H.1
Ochiai, A.2
Goya, M.3
Kanomata, N.4
Hokama, S.5
Morozumi, M.6
Sugaya, K.7
Hatano, T.8
Ogawa, Y.9
-
275
-
-
0035266413
-
Establishment of a novel species- and tissue-specific metastasis model of human prostate cancer in humanized non-obese diabetic/severe combined immunodeficient mice engrafted with human adult lung and bone
-
Yonou H., Yokose T., Kamijo T., Kanomata N., Hasebe T., Nagai K., Hatano T., Ogawa Y., Ochiai A. Establishment of a novel species- and tissue-specific metastasis model of human prostate cancer in humanized non-obese diabetic/severe combined immunodeficient mice engrafted with human adult lung and bone. Cancer Res. 2001, 61:2177-2182.
-
(2001)
Cancer Res.
, vol.61
, pp. 2177-2182
-
-
Yonou, H.1
Yokose, T.2
Kamijo, T.3
Kanomata, N.4
Hasebe, T.5
Nagai, K.6
Hatano, T.7
Ogawa, Y.8
Ochiai, A.9
-
276
-
-
34248584876
-
In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer
-
Banerjee S., Hussain M., Wang Z., Saliganan A., Che M., Bonfil D., Cher M., Sarkar F.H. In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer. Cancer Res. 2007, 67:3818-3826.
-
(2007)
Cancer Res.
, vol.67
, pp. 3818-3826
-
-
Banerjee, S.1
Hussain, M.2
Wang, Z.3
Saliganan, A.4
Che, M.5
Bonfil, D.6
Cher, M.7
Sarkar, F.H.8
-
277
-
-
36749007125
-
Adenovirus-mediated expression of TIMP-1 and TIMP-2 in bone inhibits osteolytic degradation by human prostate cancer
-
Deng X., He G., Levine A., Cao Y., Mullins C. Adenovirus-mediated expression of TIMP-1 and TIMP-2 in bone inhibits osteolytic degradation by human prostate cancer. Int. J. Cancer 2008, 122:209-218.
-
(2008)
Int. J. Cancer
, vol.122
, pp. 209-218
-
-
Deng, X.1
He, G.2
Levine, A.3
Cao, Y.4
Mullins, C.5
-
278
-
-
0033561535
-
Severe combined immunodeficient-hu model of human prostate cancer metastasis to human bone
-
Nemeth J.A., Harb J.F., Barroso U., He Z., Grignon D.J., Cher M.L. Severe combined immunodeficient-hu model of human prostate cancer metastasis to human bone. Cancer Res. 1999, 59:1987-1993.
-
(1999)
Cancer Res.
, vol.59
, pp. 1987-1993
-
-
Nemeth, J.A.1
Harb, J.F.2
Barroso, U.3
He, Z.4
Grignon, D.J.5
Cher, M.L.6
-
279
-
-
14044266315
-
Maintenance of functional human cancellous bone and human hematopoiesis in NOD/SCID mice
-
Hubin F., Humblet C., Belaid Z., Greimers R., Boniver J., Thiry A., Defresne M.P. Maintenance of functional human cancellous bone and human hematopoiesis in NOD/SCID mice. Cell Transplant. 2004, 13:823-831.
-
(2004)
Cell Transplant.
, vol.13
, pp. 823-831
-
-
Hubin, F.1
Humblet, C.2
Belaid, Z.3
Greimers, R.4
Boniver, J.5
Thiry, A.6
Defresne, M.P.7
-
280
-
-
22244455403
-
A mouse model of human breast cancer metastasis to human bone
-
Kuperwasser C., Dessain S., Bierbaum B.E., Garnet D., Sperandio K., Gauvin G.P., Naber S.P., Weinberg R.A., Rosenblatt M. A mouse model of human breast cancer metastasis to human bone. Cancer Res. 2005, 65:6130-6138.
-
(2005)
Cancer Res.
, vol.65
, pp. 6130-6138
-
-
Kuperwasser, C.1
Dessain, S.2
Bierbaum, B.E.3
Garnet, D.4
Sperandio, K.5
Gauvin, G.P.6
Naber, S.P.7
Weinberg, R.A.8
Rosenblatt, M.9
-
281
-
-
0023268536
-
Rejection of bone marrow allografts by mice with severe combined immune deficiency (SCID). Evidence that natural killer cells can mediate the specificity of marrow graft rejection
-
Murphy W.J., Kumar V., Bennett M. Rejection of bone marrow allografts by mice with severe combined immune deficiency (SCID). Evidence that natural killer cells can mediate the specificity of marrow graft rejection. J. Exp. Med. 1987, 165:1212-1217.
-
(1987)
J. Exp. Med.
, vol.165
, pp. 1212-1217
-
-
Murphy, W.J.1
Kumar, V.2
Bennett, M.3
-
282
-
-
33845811455
-
Preparing the "soil": the premetastatic niche
-
Kaplan R.N., Rafii S., Lyden D. Preparing the "soil": the premetastatic niche. Cancer Res. 2006, 66:11089-11093.
-
(2006)
Cancer Res.
, vol.66
, pp. 11089-11093
-
-
Kaplan, R.N.1
Rafii, S.2
Lyden, D.3
-
283
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
Kaplan R.N., Riba R.D., Zacharoulis S., Bramley A.H., Vincent L., Costa C., MacDonald D.D., Jin D.K., Shido K., Kerns S.A., Zhu Z., Hicklin D., Wu Y., Port J.L., Altorki N., Port E.R., Ruggero D., Shmelkov S.V., Jensen K.K., Rafii S., Lyden D. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005, 438:820-827.
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.N.1
Riba, R.D.2
Zacharoulis, S.3
Bramley, A.H.4
Vincent, L.5
Costa, C.6
MacDonald, D.D.7
Jin, D.K.8
Shido, K.9
Kerns, S.A.10
Zhu, Z.11
Hicklin, D.12
Wu, Y.13
Port, J.L.14
Altorki, N.15
Port, E.R.16
Ruggero, D.17
Shmelkov, S.V.18
Jensen, K.K.19
Rafii, S.20
Lyden, D.21
more..
-
284
-
-
79953331206
-
Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow
-
Shiozawa Y., Pedersen E.A., Havens A.M., Jung Y., Mishra A., Joseph J., Kim J.K., Patel L.R., Ying C., Ziegler A.M., Pienta M.J., Song J., Wang J., Loberg R.D., Krebsbach P.H., Pienta K.J., Taichman R.S. Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow. J. Clin. Invest. 2011, 121:1298-1312.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1298-1312
-
-
Shiozawa, Y.1
Pedersen, E.A.2
Havens, A.M.3
Jung, Y.4
Mishra, A.5
Joseph, J.6
Kim, J.K.7
Patel, L.R.8
Ying, C.9
Ziegler, A.M.10
Pienta, M.J.11
Song, J.12
Wang, J.13
Loberg, R.D.14
Krebsbach, P.H.15
Pienta, K.J.16
Taichman, R.S.17
-
285
-
-
84862825778
-
Study on the distribution features of bone metastases in prostate cancer
-
Wang C., Shen Y. Study on the distribution features of bone metastases in prostate cancer. Nucl. Med. Commun. 2012, 33:379-383.
-
(2012)
Nucl. Med. Commun.
, vol.33
, pp. 379-383
-
-
Wang, C.1
Shen, Y.2
-
286
-
-
77956764640
-
Human CD133-derived bone marrow stromal cells establish ectopic hematopoietic microenvironments in immunodeficient mice
-
Bakondi B., Spees J.L. Human CD133-derived bone marrow stromal cells establish ectopic hematopoietic microenvironments in immunodeficient mice. Biochem. Biophys. Res. Commun. 2010, 400:212-218.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.400
, pp. 212-218
-
-
Bakondi, B.1
Spees, J.L.2
-
287
-
-
0026578530
-
Characterization of cells with osteogenic potential from human marrow
-
Haynesworth S.E., Goshima J., Goldberg V.M., Caplan A.I. Characterization of cells with osteogenic potential from human marrow. Bone 1992, 13:81-88.
-
(1992)
Bone
, vol.13
, pp. 81-88
-
-
Haynesworth, S.E.1
Goshima, J.2
Goldberg, V.M.3
Caplan, A.I.4
-
288
-
-
0030934605
-
Bone formation in vivo: comparison of osteogenesis by transplanted mouse and human marrow stromal fibroblasts
-
Krebsbach P.H., Kuznetsov S.A., Satomura K., Emmons R.V., Rowe D.W., Robey P.G. Bone formation in vivo: comparison of osteogenesis by transplanted mouse and human marrow stromal fibroblasts. Transplantation 1997, 63:1059-1069.
-
(1997)
Transplantation
, vol.63
, pp. 1059-1069
-
-
Krebsbach, P.H.1
Kuznetsov, S.A.2
Satomura, K.3
Emmons, R.V.4
Rowe, D.W.5
Robey, P.G.6
-
289
-
-
0030763497
-
Single-colony derived strains of human marrow stromal fibroblasts form bone after transplantation in vivo
-
Kuznetsov S.A., Krebsbach P.H., Satomura K., Kerr J., Riminucci M., Benayahu D., Robey P.G. Single-colony derived strains of human marrow stromal fibroblasts form bone after transplantation in vivo. J. Bone Miner. Res. 1997, 12:1335-1347.
-
(1997)
J. Bone Miner. Res.
, vol.12
, pp. 1335-1347
-
-
Kuznetsov, S.A.1
Krebsbach, P.H.2
Satomura, K.3
Kerr, J.4
Riminucci, M.5
Benayahu, D.6
Robey, P.G.7
-
290
-
-
33750571850
-
Mesenchymal stem cell-organized bone marrow elements: an alternative hematopoietic progenitor resource
-
Miura Y., Gao Z., Miura M., Seo B.M., Sonoyama W., Chen W., Gronthos S., Zhang L., Shi S. Mesenchymal stem cell-organized bone marrow elements: an alternative hematopoietic progenitor resource. Stem Cells 2006, 24:2428-2436.
-
(2006)
Stem Cells
, vol.24
, pp. 2428-2436
-
-
Miura, Y.1
Gao, Z.2
Miura, M.3
Seo, B.M.4
Sonoyama, W.5
Chen, W.6
Gronthos, S.7
Zhang, L.8
Shi, S.9
-
291
-
-
35348921682
-
Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment
-
Sacchetti B., Funari A., Michienzi S., Di Cesare S., Piersanti S., Saggio I., Tagliafico E., Ferrari S., Robey P.G., Riminucci M., Bianco P. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 2007, 131:324-336.
-
(2007)
Cell
, vol.131
, pp. 324-336
-
-
Sacchetti, B.1
Funari, A.2
Michienzi, S.3
Di Cesare, S.4
Piersanti, S.5
Saggio, I.6
Tagliafico, E.7
Ferrari, S.8
Robey, P.G.9
Riminucci, M.10
Bianco, P.11
-
292
-
-
78649685993
-
Ectopic human mesenchymal stem cell-coated scaffolds in NOD/SCID mice: an in vivo model of the leukemia niche
-
Vaiselbuh S.R., Edelman M., Lipton J.M., Liu J.M. Ectopic human mesenchymal stem cell-coated scaffolds in NOD/SCID mice: an in vivo model of the leukemia niche. Tissue Eng. Part C Methods 2010, 16:1523-1531.
-
(2010)
Tissue Eng. Part C Methods
, vol.16
, pp. 1523-1531
-
-
Vaiselbuh, S.R.1
Edelman, M.2
Lipton, J.M.3
Liu, J.M.4
-
293
-
-
84874615532
-
Engineering of a functional bone organ through endochondral ossification
-
Scotti C., Piccinini E., Takizawa H., Todorov A., Bourgine P., Papadimitropoulos A., Barbero A., Manz M.G., Martin I. Engineering of a functional bone organ through endochondral ossification. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:3997-4002.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 3997-4002
-
-
Scotti, C.1
Piccinini, E.2
Takizawa, H.3
Todorov, A.4
Bourgine, P.5
Papadimitropoulos, A.6
Barbero, A.7
Manz, M.G.8
Martin, I.9
-
294
-
-
0038652866
-
Skeletal homeostasis in tissue-engineered bone
-
Schneider A., Taboas J.M., McCauley L.K., Krebsbach P.H. Skeletal homeostasis in tissue-engineered bone. J. Orthop. Res. 2003, 21:859-864.
-
(2003)
J. Orthop. Res.
, vol.21
, pp. 859-864
-
-
Schneider, A.1
Taboas, J.M.2
McCauley, L.K.3
Krebsbach, P.H.4
-
295
-
-
77950974931
-
An in vivo model to study and manipulate the hematopoietic stem cell niche
-
Song J., Kiel M.J., Wang Z., Wang J., Taichman R.S., Morrison S.J., Krebsbach P.H. An in vivo model to study and manipulate the hematopoietic stem cell niche. Blood 2010, 115:2592-2600.
-
(2010)
Blood
, vol.115
, pp. 2592-2600
-
-
Song, J.1
Kiel, M.J.2
Wang, Z.3
Wang, J.4
Taichman, R.S.5
Morrison, S.J.6
Krebsbach, P.H.7
-
296
-
-
84879442660
-
An ectopic stromal implant model for hematopoietic reconstitution and in vivo evaluation of bone marrow niches
-
Paraguassu-Braga F.H., Alves A.P., Santos I.M., Bonamino M., Bonomo A. An ectopic stromal implant model for hematopoietic reconstitution and in vivo evaluation of bone marrow niches. Cell Transplant. 2012, 21:2677-2688.
-
(2012)
Cell Transplant.
, vol.21
, pp. 2677-2688
-
-
Paraguassu-Braga, F.H.1
Alves, A.P.2
Santos, I.M.3
Bonamino, M.4
Bonomo, A.5
-
297
-
-
0017153994
-
Collagenous bone matrix-induced endochondral ossification hemopoiesis
-
Reddi A.H., Anderson W.A. Collagenous bone matrix-induced endochondral ossification hemopoiesis. J. Cell Biol. 1976, 69:557-572.
-
(1976)
J. Cell Biol.
, vol.69
, pp. 557-572
-
-
Reddi, A.H.1
Anderson, W.A.2
-
298
-
-
84861524484
-
Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment
-
Chen Y., Jacamo R., Shi Y.X., Wang R.Y., Battula V.L., Konoplev S., Strunk D., Hofmann N.A., Reinisch A., Konopleva M., Andreeff M. Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment. Blood 2012, 119:4971-4980.
-
(2012)
Blood
, vol.119
, pp. 4971-4980
-
-
Chen, Y.1
Jacamo, R.2
Shi, Y.X.3
Wang, R.Y.4
Battula, V.L.5
Konoplev, S.6
Strunk, D.7
Hofmann, N.A.8
Reinisch, A.9
Konopleva, M.10
Andreeff, M.11
-
299
-
-
33646912241
-
A novel human osteoblast-derived severe combined immunodeficiency mouse model of bone metastasis
-
Schuster J., Zhang J., Longo M. A novel human osteoblast-derived severe combined immunodeficiency mouse model of bone metastasis. J. Neurosurg. Spine 2006, 4:388-391.
-
(2006)
J. Neurosurg. Spine
, vol.4
, pp. 388-391
-
-
Schuster, J.1
Zhang, J.2
Longo, M.3
-
300
-
-
35948949806
-
Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model
-
Moreau J.E., Anderson K., Mauney J.R., Nguyen T., Kaplan D.L., Rosenblatt M. Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model. Cancer Res. 2007, 67:10304-10308.
-
(2007)
Cancer Res.
, vol.67
, pp. 10304-10308
-
-
Moreau, J.E.1
Anderson, K.2
Mauney, J.R.3
Nguyen, T.4
Kaplan, D.L.5
Rosenblatt, M.6
-
301
-
-
78650337010
-
Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis
-
Goldstein R.H., Reagan M.R., Anderson K., Kaplan D.L., Rosenblatt M. Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. Cancer Res. 2010, 70:10044-10050.
-
(2010)
Cancer Res.
, vol.70
, pp. 10044-10050
-
-
Goldstein, R.H.1
Reagan, M.R.2
Anderson, K.3
Kaplan, D.L.4
Rosenblatt, M.5
-
302
-
-
36549016147
-
Studies of osteotropism on both sides of the breast cancer-bone interaction
-
Moreau J., Anderson K.M., Mauney J.R., Kaplan D., Rosenblatt M. Studies of osteotropism on both sides of the breast cancer-bone interaction. Ann. N. Y. Acad. Sci. 2007, 1117:328-344.
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1117
, pp. 328-344
-
-
Moreau, J.1
Anderson, K.M.2
Mauney, J.R.3
Kaplan, D.4
Rosenblatt, M.5
-
303
-
-
84887421660
-
Tumor metastasis: moving new biological insights into the clinic
-
Wan L., Pantel K., Kang Y. Tumor metastasis: moving new biological insights into the clinic. Nat. Med. 2013, 19:1450-1464.
-
(2013)
Nat. Med.
, vol.19
, pp. 1450-1464
-
-
Wan, L.1
Pantel, K.2
Kang, Y.3
-
304
-
-
34249864531
-
Biomechanics and biophysics of cancer cells
-
Suresh S. Biomechanics and biophysics of cancer cells. Acta Biomater. 2007, 3:413-438.
-
(2007)
Acta Biomater.
, vol.3
, pp. 413-438
-
-
Suresh, S.1
-
305
-
-
68549112897
-
Mechanics, malignancy, and metastasis: the force journey of a tumor cell
-
Kumar S., Weaver V.M. Mechanics, malignancy, and metastasis: the force journey of a tumor cell. Cancer Metastasis Rev. 2009, 28:113-127.
-
(2009)
Cancer Metastasis Rev.
, vol.28
, pp. 113-127
-
-
Kumar, S.1
Weaver, V.M.2
-
306
-
-
84867117776
-
Cell stiffness is a biomarker of the metastatic potential of ovarian cancer cells
-
Xu W., Mezencev R., Kim B., Wang L., McDonald J., Sulchek T. Cell stiffness is a biomarker of the metastatic potential of ovarian cancer cells. PLoS One 2012, 7:e46609.
-
(2012)
PLoS One
, vol.7
, pp. e46609
-
-
Xu, W.1
Mezencev, R.2
Kim, B.3
Wang, L.4
McDonald, J.5
Sulchek, T.6
-
307
-
-
79960942460
-
Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines
-
Swaminathan V., Mythreye K., O'Brien E.T., Berchuck A., Blobe G.C., Superfine R. Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines. Cancer Res. 2011, 71:5075-5080.
-
(2011)
Cancer Res.
, vol.71
, pp. 5075-5080
-
-
Swaminathan, V.1
Mythreye, K.2
O'Brien, E.T.3
Berchuck, A.4
Blobe, G.C.5
Superfine, R.6
-
309
-
-
36849037967
-
Nanomechanical analysis of cells from cancer patients
-
Cross S.E., Jin Y.S., Rao J., Gimzewski J.K. Nanomechanical analysis of cells from cancer patients. Nat. Nanotechnol. 2007, 2:780-783.
-
(2007)
Nat. Nanotechnol.
, vol.2
, pp. 780-783
-
-
Cross, S.E.1
Jin, Y.S.2
Rao, J.3
Gimzewski, J.K.4
-
310
-
-
84862688660
-
Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells
-
Sharma S., Santiskulvong C., Bentolila L.A., Rao J.Y., Dorigo O., Gimzewski J.K. Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells. Nanomedicine 2012, 8:757-766.
-
(2012)
Nanomedicine
, vol.8
, pp. 757-766
-
-
Sharma, S.1
Santiskulvong, C.2
Bentolila, L.A.3
Rao, J.Y.4
Dorigo, O.5
Gimzewski, J.K.6
-
311
-
-
84880654027
-
A multiscale road map of cancer spheroids - incorporating experimental and mathematical modelling to understand cancer progression
-
Loessner D., Little J.P., Pettet G.J., Hutmacher D.W. A multiscale road map of cancer spheroids - incorporating experimental and mathematical modelling to understand cancer progression. J. Cell Sci. 2013, 126:2761-2771.
-
(2013)
J. Cell Sci.
, vol.126
, pp. 2761-2771
-
-
Loessner, D.1
Little, J.P.2
Pettet, G.J.3
Hutmacher, D.W.4
-
312
-
-
79960490878
-
Multiscale cancer modeling
-
Deisboeck T.S., Wang Z., Macklin P., Cristini V. Multiscale cancer modeling. Annu. Rev. Biomed. Eng. 2011, 13:127-155.
-
(2011)
Annu. Rev. Biomed. Eng.
, vol.13
, pp. 127-155
-
-
Deisboeck, T.S.1
Wang, Z.2
Macklin, P.3
Cristini, V.4
-
314
-
-
24944547482
-
Tensional homeostasis and the malignant phenotype
-
Paszek M.J., Zahir N., Johnson K.R., Lakins J.N., Rozenberg G.I., Gefen A., Reinhart-King C.A., Margulies S.S., Dembo M., Boettiger D., Hammer D.A., Weaver V.M. Tensional homeostasis and the malignant phenotype. Cancer Cell 2005, 8:241-254.
-
(2005)
Cancer Cell
, vol.8
, pp. 241-254
-
-
Paszek, M.J.1
Zahir, N.2
Johnson, K.R.3
Lakins, J.N.4
Rozenberg, G.I.5
Gefen, A.6
Reinhart-King, C.A.7
Margulies, S.S.8
Dembo, M.9
Boettiger, D.10
Hammer, D.A.11
Weaver, V.M.12
-
315
-
-
84886426170
-
Cancer cell glycocalyx mediates mechanotransduction and flow-regulated invasion
-
Qazi H., Palomino R., Shi Z.D., Munn L.L., Tarbell J.M. Cancer cell glycocalyx mediates mechanotransduction and flow-regulated invasion. Integr. Biol. 2013, 5:1334-1343.
-
(2013)
Integr. Biol.
, vol.5
, pp. 1334-1343
-
-
Qazi, H.1
Palomino, R.2
Shi, Z.D.3
Munn, L.L.4
Tarbell, J.M.5
-
316
-
-
77952010690
-
Computational study of proteolysis-driven single cell migration in a three-dimensional matrix
-
Harjanto D., Zaman M.H. Computational study of proteolysis-driven single cell migration in a three-dimensional matrix. Ann. Biomed. Eng. 2010, 38:1815-1825.
-
(2010)
Ann. Biomed. Eng.
, vol.38
, pp. 1815-1825
-
-
Harjanto, D.1
Zaman, M.H.2
-
317
-
-
84900001671
-
An integrated computational model of the bone microenvironment in bone-metastatic prostate cancer
-
Araujo A., Cook L.M., Lynch C.C., Basanta D. An integrated computational model of the bone microenvironment in bone-metastatic prostate cancer. Cancer Res. 2014, 74:2391-2401.
-
(2014)
Cancer Res.
, vol.74
, pp. 2391-2401
-
-
Araujo, A.1
Cook, L.M.2
Lynch, C.C.3
Basanta, D.4
-
318
-
-
84872318735
-
Modeling extracellular matrix reorganization in 3D environments
-
Harjanto D., Zaman M.H. Modeling extracellular matrix reorganization in 3D environments. PLoS One 2013, 8:e52509.
-
(2013)
PLoS One
, vol.8
, pp. e52509
-
-
Harjanto, D.1
Zaman, M.H.2
-
319
-
-
66849101632
-
Adhesion signaling - crosstalk between integrins, Src and Rho
-
Huveneers S., Danen E.H. Adhesion signaling - crosstalk between integrins, Src and Rho. J. Cell Sci. 2009, 122:1059-1069.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 1059-1069
-
-
Huveneers, S.1
Danen, E.H.2
-
320
-
-
84883118516
-
Cell biology. Strength under tension
-
Bainer R., Weaver V. Cell biology. Strength under tension. Science 2013, 341:965-966.
-
(2013)
Science
, vol.341
, pp. 965-966
-
-
Bainer, R.1
Weaver, V.2
-
321
-
-
84883059455
-
Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation
-
Swift J., Ivanovska I.L., Buxboim A., Harada T., Dingal P.C., Pinter J., Pajerowski J.D., Spinler K.R., Shin J.W., Tewari M., Rehfeldt F., Speicher D.W., Discher D.E. Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science 2013, 341:1240104.
-
(2013)
Science
, vol.341
, pp. 1240104
-
-
Swift, J.1
Ivanovska, I.L.2
Buxboim, A.3
Harada, T.4
Dingal, P.C.5
Pinter, J.6
Pajerowski, J.D.7
Spinler, K.R.8
Shin, J.W.9
Tewari, M.10
Rehfeldt, F.11
Speicher, D.W.12
Discher, D.E.13
-
322
-
-
84872813881
-
Cell biology. Deconstructing dimensionality
-
Schwartz M.A., Chen C.S. Cell biology. Deconstructing dimensionality. Science 2013, 339:402-404.
-
(2013)
Science
, vol.339
, pp. 402-404
-
-
Schwartz, M.A.1
Chen, C.S.2
|