Improved quenched fluorescent probe for imaging of cysteine cathepsin activity

Journal of the American Chemical Society

Volumn 135, Issue 39, 2013, Pages 14726-14730

  Verdoes, Martijn ^a,b   Oresic Bender, Kristina ^a   Segal, Ehud ^a   Van Der Linden, Wouter A ^a   Syed, Salahuddin ^a   Withana, Nimali P ^a   Sanman, Laura E ^a   Bogyo, Matthew ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVITY-BASED PROBE; CELLULAR PHYSIOLOGY; ELECTROPHILES; FLUORESCENT PROBES; HUMAN DISEASE; IN-VIVO; TUMOR IMAGING;

KETONES; TUMORS;

AMINO ACIDS;

CATHEPSIN B; CATHEPSIN L; CATHEPSIN S; CATHEPSIN X; CYSTEINE; ELECTROPHILE; FLUORESCENT DYE; KETONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ELECTROPHILICITY; ENZYME ACTIVITY; FLUORESCENCE IMAGING; HYDROPHILICITY; MOUSE; NONHUMAN; NUCLEOPHILICITY; SYNTHESIS;

ANIMALS; BREAST; BREAST NEOPLASMS; CELL LINE; CELLS, CULTURED; CYSTEINE; CYSTEINE PROTEASES; FEMALE; FLUORESCENT DYES; HUMANS; KETONES; MICE; OPTICAL IMAGING;

EID: 84885112885     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4056068     Document Type: Article

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