메뉴 건너뛰기




Volumn 15, Issue 8, 2009, Pages 1443-1461

Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell

Author keywords

Cancer cell circuit; miRNAs; Molecular switch; Oncomirs; Tumor suppressor miRNAs

Indexed keywords

MICRORNA;

EID: 67651002343     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.1534709     Document Type: Review
Times cited : (146)

References (216)
  • 1
    • 34250843675 scopus 로고    scopus 로고
    • The micro-RNA miR-206 targets the human estrogen receptor-α, and represses ERα mRNA and protein expression in breast cancer cell lines
    • Adams BD, Furneaux H, White B. 2007. The micro-RNA miR-206 targets the human estrogen receptor-α, and represses ERα mRNA and protein expression in breast cancer cell lines. Mol Endocrinol 21: 1132-1147.
    • (2007) Mol Endocrinol , vol.21 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.3
  • 2
    • 35548995316 scopus 로고    scopus 로고
    • Down-regulation of miR-143 and miR-145 in B-cell malignancies
    • Akao Y, Nakagawa Y, Kitabe Y, Kinoshita T, Naoe T. 2007. Down-regulation of miR-143 and miR-145 in B-cell malignancies. Cancer Sci 12: 1914-1920.
    • (2007) Cancer Sci , vol.12 , pp. 1914-1920
    • Akao, Y.1    Nakagawa, Y.2    Kitabe, Y.3    Kinoshita, T.4    Naoe, T.5
  • 4
    • 28044471565 scopus 로고    scopus 로고
    • MicroRNA functions in animal development and human disease
    • Alvarez-Garcia I, Miska EA. 2005. MicroRNA functions in animal development and human disease. Development 132: 4653-4662.
    • (2005) Development , vol.132 , pp. 4653-4662
    • Alvarez-Garcia, I.1    Miska, E.A.2
  • 5
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally down-regulates tumor suppressor Pdcd4 and stimulates invasion, intravasation, and metastasis in colorectal cancer
    • Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S, Allgayer H. 2008. MicroRNA-21 (miR-21) post-transcriptionally down-regulates tumor suppressor Pdcd4 and stimulates invasion, intravasation, and metastasis in colorectal cancer. Oncogene 27: 2128-2136.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6    Allgayer, H.7
  • 7
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. 2004. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 9
    • 0035997389 scopus 로고    scopus 로고
    • RNA editing by adenosine deaminases that act on RNA
    • Bass BL. 2002. RNA editing by adenosine deaminases that act on RNA. Annu Rev Biochem 71: 817-846.
    • (2002) Annu Rev Biochem , vol.71 , pp. 817-846
    • Bass, B.L.1
  • 12
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E, Caudy AA, Hammond SM, Hannon GJ. 2001. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363-366.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 13
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signalling at the telomere
    • Blackburn EH. 2001. Switching and signalling at the telomere. Cell 1067: 661-673.
    • (2001) Cell , vol.1067 , pp. 661-673
    • Blackburn, E.H.1
  • 17
    • 8144222388 scopus 로고    scopus 로고
    • The emerging roles of human tissue kallikreins in cancer
    • Borgoño CA, Diamandis EP. 2004. The emerging roles of human tissue kallikreins in cancer. Nat Rev Cancer 4: 876-890.
    • (2004) Nat Rev Cancer , vol.4 , pp. 876-890
    • Borgoño, C.A.1    Diamandis, E.P.2
  • 21
    • 17244375710 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells
    • Cai X, Lu S, Zhang Z, Gonzalez CM, Damania B, Cullen BR. 2005. Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc Natl Acad Sci 102: 5570-5575.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 5570-5575
    • Cai, X.1    Lu, S.2    Zhang, Z.3    Gonzalez, C.M.4    Damania, B.5    Cullen, B.R.6
  • 22
    • 33750305743 scopus 로고    scopus 로고
    • Human papillomavirus genotype 31 does not express detectable microRNA levels during latent or productive virus replication
    • Cai X, Li G, Laimins LA, Cullen BR. 2006. Human papillomavirus genotype 31 does not express detectable microRNA levels during latent or productive virus replication. J Virol 80: 10890-10893.
    • (2006) J Virol , vol.80 , pp. 10890-10893
    • Cai, X.1    Li, G.2    Laimins, L.A.3    Cullen, B.R.4
  • 23
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin GA, Croce CM. 2006. MicroRNA signatures in human cancers. Nat Rev Cancer 6: 857-866.
    • (2006) Nat Rev Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 28
    • 38949193234 scopus 로고    scopus 로고
    • Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5
    • Chen Y, Gorski DH. 2008. Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood 111: 1217-1226.
    • (2008) Blood , vol.111 , pp. 1217-1226
    • Chen, Y.1    Gorski, D.H.2
  • 30
    • 54249117763 scopus 로고    scopus 로고
    • A SNP in a let-7 microRNA complementary site in the KRAS 3′ untranslated region increases nonsmall cell lung cancer risk
    • Chin LJ, Ratner E, Leng S, Zhai R, Nallur S, Babar I, Muller RU, Straka E, Su L, Burki EA, et al. 2008. A SNP in a let-7 microRNA complementary site in the KRAS 3′ untranslated region increases nonsmall cell lung cancer risk. Cancer Res 68: 8535-8540.
    • (2008) Cancer Res , vol.68 , pp. 8535-8540
    • Chin, L.J.1    Ratner, E.2    Leng, S.3    Zhai, R.4    Nallur, S.5    Babar, I.6    Muller, R.U.7    Straka, E.8    Su, L.9    Burki, E.A.10
  • 33
    • 36649025655 scopus 로고    scopus 로고
    • OncomiRs: The discovery and progress of microRNAs in cancers
    • Cho WC. 2007. OncomiRs: The discovery and progress of microRNAs in cancers. Mol Cancer 6: 60.
    • (2007) Mol Cancer , vol.6 , pp. 60
    • Cho, W.C.1
  • 34
    • 47549102771 scopus 로고    scopus 로고
    • Kallikreins as microRNA targets: An in silico and experimental-based analysis
    • Chow TF, Chow M, Earle T, El-Said H, Diamandis EP, Yousef GM. 2008. Kallikreins as microRNA targets: An in silico and experimental-based analysis. Biol Chem 389: 731-738.
    • (2008) Biol Chem , vol.389 , pp. 731-738
    • Chow, T.F.1    Chow, M.2    Earle, T.3    El-Said, H.4    Diamandis, E.P.5    Yousef, G.M.6
  • 38
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and microRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • Corney DC, Flesken-Nikitin A, Godwin AK, Wang W, Nikitin AY. 2007. MicroRNA-34b and microRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res 67: 8433-8438.
    • (2007) Cancer Res , vol.67 , pp. 8433-8438
    • Corney, D.C.1    Flesken-Nikitin, A.2    Godwin, A.K.3    Wang, W.4    Nikitin, A.Y.5
  • 39
    • 35148900227 scopus 로고    scopus 로고
    • MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delived S-TRAIL in human gliomas
    • Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K. 2007. MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delived S-TRAIL in human gliomas. Cancer Res 67: 8994-9000.
    • (2007) Cancer Res , vol.67 , pp. 8994-9000
    • Corsten, M.F.1    Miranda, R.2    Kasmieh, R.3    Krichevsky, A.M.4    Weissleder, R.5    Shah, K.6
  • 40
    • 34948903306 scopus 로고    scopus 로고
    • Retroviral insertional activation of the Fli-3 locus in erythroleukemias encoding a cluster of microRNAs that convert Epo-induced differentiation to proliferation
    • Cui JW, Li YJ, Sarkar A, Brown J, Tan YH, Premyslova M, Michaud C, Iscove N, Wang GJ, Ben-David Y. 2007. Retroviral insertional activation of the Fli-3 locus in erythroleukemias encoding a cluster of microRNAs that convert Epo-induced differentiation to proliferation. Blood 100: 2631-2640.
    • (2007) Blood , vol.100 , pp. 2631-2640
    • Cui, J.W.1    Li, Y.J.2    Sarkar, A.3    Brown, J.4    Tan, Y.H.5    Premyslova, M.6    Michaud, C.7    Iscove, N.8    Wang, G.J.9    Ben-David, Y.10
  • 44
    • 33745700209 scopus 로고    scopus 로고
    • Sequence variations of microRNAs in human cancer: Alterations in predicted secondary structure do not affect processing
    • Diederich S, Haber DA. 2006. Sequence variations of microRNAs in human cancer: Alterations in predicted secondary structure do not affect processing. Cancer Res 66: 6097-6104.
    • (2006) Cancer Res , vol.66 , pp. 6097-6104
    • Diederich, S.1    Haber, D.A.2
  • 45
    • 28044455435 scopus 로고    scopus 로고
    • MicroPrimer: The biogenesis and function of microRNA
    • Du T, Zamore PD. 2005. MicroPrimer: The biogenesis and function of microRNA. Development 132: 4645-4652.
    • (2005) Development , vol.132 , pp. 4645-4652
    • Du, T.1    Zamore, P.D.2
  • 46
    • 34447319406 scopus 로고    scopus 로고
    • Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA
    • Duan R, Pak C, Jin P. 2007. Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA. Hum Mol Genet 16: 1124-1131.
    • (2007) Hum Mol Genet , vol.16 , pp. 1124-1131
    • Duan, R.1    Pak, C.2    Jin, P.3
  • 47
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • Ebert MS, Neilson JR, Sharp PA. 2007. MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells. Nat Methods 4: 721-726.
    • (2007) Nat Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 50
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - MicroRNAs with a role in cancer
    • Esquela-Kerscher A, Slack FJ. 2006. Oncomirs - MicroRNAs with a role in cancer. Nat Rev Cancer 6: 259-269.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 51
    • 38649105459 scopus 로고    scopus 로고
    • miR-122 targeting with LNA/2′-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA peptide conjugates
    • Fabani MM, Gait MJ. 2008. miR-122 targeting with LNA/2′-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA peptide conjugates. RNA 14: 336-346.
    • (2008) RNA , vol.14 , pp. 336-346
    • Fabani, M.M.1    Gait, M.J.2
  • 54
    • 0002799842 scopus 로고    scopus 로고
    • Growth factors
    • eds. JF Holland et al, pp, Williams and Wilkins, Baltimore, MD
    • Fedi P, Tronick SR, Aaronson SA. 1997. Growth factors. In Cancer medicine (eds. JF Holland et al.), pp. 41-64. Williams and Wilkins, Baltimore, MD.
    • (1997) Cancer medicine , pp. 41-64
    • Fedi, P.1    Tronick, S.R.2    Aaronson, S.A.3
  • 55
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • Filipowicz W, Bhattacharyya SN, Sonenberg N. 2008. Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight? Nat Rev Genet 9: 102-114.
    • (2008) Nat Rev Genet , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 57
    • 20444479844 scopus 로고    scopus 로고
    • On the in vitro and in vivo properties of four locked nucleic acid nucleotides incorporated into an anti-H-Ras antisense oligonucleotides
    • Fluiter K, Frieden M, Vreijling J, Rosebohm C, De Wissel MB, Christensen SM, Koch T, Ørum H, Baas F. 2005. On the in vitro and in vivo properties of four locked nucleic acid nucleotides incorporated into an anti-H-Ras antisense oligonucleotides. Chem-BioChem 6: 1104-1109.
    • (2005) Chem-BioChem , vol.6 , pp. 1104-1109
    • Fluiter, K.1    Frieden, M.2    Vreijling, J.3    Rosebohm, C.4    De Wissel, M.B.5    Christensen, S.M.6    Koch, T.7    Ørum, H.8    Baas, F.9
  • 58
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A, Lund AH. 2008. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 283: 1026-1033.
    • (2008) J Biol Chem , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 59
    • 54449097149 scopus 로고    scopus 로고
    • A search for conserved sequences in coding regions reveals that the let-7 microRNA targets dicer within its coding sequence
    • Forman JJ, Legesse-Miller A, Coller HA. 2008. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets dicer within its coding sequence. Proc Natl Acad Sci 39: 14879-14884.
    • (2008) Proc Natl Acad Sci , vol.39 , pp. 14879-14884
    • Forman, J.J.1    Legesse-Miller, A.2    Coller, H.A.3
  • 63
    • 9144225636 scopus 로고    scopus 로고
    • The Microprocessor complex mediates the genesis of microRNAs
    • Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. 2004. The Microprocessor complex mediates the genesis of microRNAs. Nature 432: 235-240.
    • (2004) Nature , vol.432 , pp. 235-240
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 64
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and post-transcriptional gene silencing
    • Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. 2005. Human RISC couples microRNA biogenesis and post-transcriptional gene silencing. Cell 123: 631-640.
    • (2005) Cell , vol.123 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 65
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, Baillie DL, Fire A, Ruvkun G, Mello CC. 2001. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106: 23-34.
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5    Ha, I.6    Baillie, D.L.7    Fire, A.8    Ruvkun, G.9    Mello, C.C.10
  • 66
    • 33646168051 scopus 로고    scopus 로고
    • A combined computational and microarray-based approach identifies novel microRNAs encoded by human g-herpesviruses
    • Grundhoff A, Sullivan CS, Ganem D. 2006. A combined computational and microarray-based approach identifies novel microRNAs encoded by human g-herpesviruses. RNA 12: 733-750.
    • (2006) RNA , vol.12 , pp. 733-750
    • Grundhoff, A.1    Sullivan, C.S.2    Ganem, D.3
  • 67
    • 33645729182 scopus 로고    scopus 로고
    • Immunobiology and pathogenesis of viral hepatitis
    • Guidotti LG, Chisari FV. 2006. Immunobiology and pathogenesis of viral hepatitis. Annu Rev Pathol 1: 23-61.
    • (2006) Annu Rev Pathol , vol.1 , pp. 23-61
    • Guidotti, L.G.1    Chisari, F.V.2
  • 69
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. 2000. The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 70
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • Hannon GJ, Beach D. 1994. p15INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371: 257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 75
    • 35748961986 scopus 로고    scopus 로고
    • p53 enters the microRNA world
    • Hermeking H. 2007. p53 enters the microRNA world. Cancer Cell 12: 411-418.
    • (2007) Cancer Cell , vol.12 , pp. 411-418
    • Hermeking, H.1
  • 76
    • 33947196379 scopus 로고    scopus 로고
    • Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma
    • Horikawa T, Yang J, Kondo S, Yoshizaki T, Joab I, Furukawa M, Pagano JS. 2007. Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma. Cancer Res 67: 1970-1978.
    • (2007) Cancer Res , vol.67 , pp. 1970-1978
    • Horikawa, T.1    Yang, J.2    Kondo, S.3    Yoshizaki, T.4    Joab, I.5    Furukawa, M.6    Pagano, J.S.7
  • 77
    • 33750376591 scopus 로고    scopus 로고
    • Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA
    • Hossain A, Kuo MT, Saunders GF. 2006. Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA. Mol Cell Biol 26: 8191-8201.
    • (2006) Mol Cell Biol , vol.26 , pp. 8191-8201
    • Hossain, A.1    Kuo, M.T.2    Saunders, G.F.3
  • 78
    • 54949154476 scopus 로고    scopus 로고
    • miRNA-directed regulation of VEGF and other angiogenic factors under hypoxia
    • doi: 10.1371/journal.pone. 0000116
    • Hua Z, Lv Q, Ye W, Wong CKA, Cai G, Gu D, Ji Y, Zhao C, Wang J, Yang BB, et al. 2006. miRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS One 1: e116. doi: 10.1371/journal.pone. 0000116.
    • (2006) PLoS One , vol.1
    • Hua, Z.1    Lv, Q.2    Ye, W.3    Wong, C.K.A.4    Cai, G.5    Gu, D.6    Ji, Y.7    Zhao, C.8    Wang, J.9    Yang, B.B.10
  • 80
    • 37549014207 scopus 로고    scopus 로고
    • Argonaute proteins: Key players in RNA silencing
    • Hutvágner G, Simard MJ. 2008. Argonaute proteins: Key players in RNA silencing. Nat Rev Mol Cell Biol 9: 22-32.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 22-32
    • Hutvágner, G.1    Simard, M.J.2
  • 81
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvágner G, McLachlan J, Pasquinelli AE, Bálint E, Tuschl T, Zamore PD. 2001. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293: 834-838.
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvágner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Bálint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 82
    • 33846699083 scopus 로고    scopus 로고
    • A hexanucleotide element directs miRNA nuclear import
    • Hwang H-W, Wentzel EA, Mendell JT. 2007. A hexanucleotide element directs miRNA nuclear import. Science 315: 97-100.
    • (2007) Science , vol.315 , pp. 97-100
    • Hwang, H.-W.1    Wentzel, E.A.2    Mendell, J.T.3
  • 83
    • 37249031072 scopus 로고    scopus 로고
    • A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells
    • Ibarra I, Erlich Y, Muthuswamy SK, Sachidanandam R, Hanon GJ. 2007. A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells. Genes & Dev 21: 3238-3243.
    • (2007) Genes & Dev , vol.21 , pp. 3238-3243
    • Ibarra, I.1    Erlich, Y.2    Muthuswamy, S.K.3    Sachidanandam, R.4    Hanon, G.J.5
  • 86
    • 33644801773 scopus 로고    scopus 로고
    • Alternative initiation and splicing in dicer gene expression in human breast cells
    • Irvin-Wilson CV, Chaudhuri G. 2005. Alternative initiation and splicing in dicer gene expression in human breast cells. Breast Cancer Res 7: R563-R569.
    • (2005) Breast Cancer Res , vol.7
    • Irvin-Wilson, C.V.1    Chaudhuri, G.2
  • 87
    • 18844380174 scopus 로고    scopus 로고
    • Polymorphisms in human pre-miRNAs
    • Iwai N, Naraba H. 2005. Polymorphisms in human pre-miRNAs. Biochem Biophys Res Commun 331: 1439-1444.
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 1439-1444
    • Iwai, N.1    Naraba, H.2
  • 88
    • 27244433702 scopus 로고    scopus 로고
    • Real-time expression profiling of microRNA precursors in human cancer cell lines
    • Jiang J, Lee EJ, Gusev Y, Schmittgen TD. 2005. Real-time expression profiling of microRNA precursors in human cancer cell lines. Nucleic Acids Res 33: 5394-5403.
    • (2005) Nucleic Acids Res , vol.33 , pp. 5394-5403
    • Jiang, J.1    Lee, E.J.2    Gusev, Y.3    Schmittgen, T.D.4
  • 89
    • 7944232720 scopus 로고    scopus 로고
    • RNA and microRNAs in fragile X mental retardation
    • Jin P, Alisch RS, Warren ST. 2004. RNA and microRNAs in fragile X mental retardation. Nat Cell Biol 6: 1048-1053.
    • (2004) Nat Cell Biol , vol.6 , pp. 1048-1053
    • Jin, P.1    Alisch, R.S.2    Warren, S.T.3
  • 90
    • 34047129198 scopus 로고    scopus 로고
    • HBV-encoded microRNA candidate and its target
    • Jin WB, Wu FL, Kong D, Guo AG. 2007. HBV-encoded microRNA candidate and its target. Comput Biol Chem 31: 124-126.
    • (2007) Comput Biol Chem , vol.31 , pp. 124-126
    • Jin, W.B.1    Wu, F.L.2    Kong, D.3    Guo, A.G.4
  • 93
  • 95
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH. 2001. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes & Dev 15: 2654-2659.
    • (2001) Genes & Dev , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.6
  • 99
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • Korpal M, Lee ES, Hu G, Kang Y. 2008. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 283: 14910-14914.
    • (2008) J Biol Chem , vol.283 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 101
    • 34447632218 scopus 로고    scopus 로고
    • Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis
    • Kuehbacher A, Urbich C, Zeiher AM, Dimmeler S. 2007. Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis. Circ Res 101: 59-68.
    • (2007) Circ Res , vol.101 , pp. 59-68
    • Kuehbacher, A.1    Urbich, C.2    Zeiher, A.M.3    Dimmeler, S.4
  • 103
    • 34247593034 scopus 로고    scopus 로고
    • Impaired microRNA processing enhances cellular transformation and tumorigenesis
    • Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T. 2007. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 39: 673-677.
    • (2007) Nat Genet , vol.39 , pp. 673-677
    • Kumar, M.S.1    Lu, J.2    Mercer, K.L.3    Golub, T.R.4    Jacks, T.5
  • 105
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee YS, Dutta A. 2007. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes & Dev 21: 1025-1030.
    • (2007) Genes & Dev , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 106
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. 1993. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 5: 843-854.
    • (1993) Cell , vol.5 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 108
    • 38049103266 scopus 로고    scopus 로고
    • MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression
    • Lee DY, Deng Z, Wang CH, Yang BB. 2007a. MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression. Proc Natl Acad Sci 104: 20350-20355.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 20350-20355
    • Lee, D.Y.1    Deng, Z.2    Wang, C.H.3    Yang, B.B.4
  • 112
    • 34547610957 scopus 로고    scopus 로고
    • uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells
    • Lester RD, Jo M, Montel V, Takimoto S, Gonias SL. 2007. uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells. J Cell Biol 178: 425-436.
    • (2007) J Cell Biol , vol.178 , pp. 425-436
    • Lester, R.D.1    Jo, M.2    Montel, V.3    Takimoto, S.4    Gonias, S.L.5
  • 113
    • 33746725256 scopus 로고    scopus 로고
    • Inhibition of PRL-3 gene expression in gastric cancer cell line SGC7901 via microRNA suppressed reduces peritoneal metastasis
    • Li Z, Zhan W, Wang Z, Zhu B, He Y, Peng J, Cai S, Ma J. 2006. Inhibition of PRL-3 gene expression in gastric cancer cell line SGC7901 via microRNA suppressed reduces peritoneal metastasis. Biochem Biophys Res Commun 348: 229-237.
    • (2006) Biochem Biophys Res Commun , vol.348 , pp. 229-237
    • Li, Z.1    Zhan, W.2    Wang, Z.3    Zhu, B.4    He, Y.5    Peng, J.6    Cai, S.7    Ma, J.8
  • 117
    • 38349131954 scopus 로고    scopus 로고
    • MicroRNAs: Biogenesis and molecular functions
    • Liu X, Fortin K, Mourelatos Z. 2008. MicroRNAs: Biogenesis and molecular functions. Brain Pathol 18: 113-121.
    • (2008) Brain Pathol , vol.18 , pp. 113-121
    • Liu, X.1    Fortin, K.2    Mourelatos, Z.3
  • 121
    • 34748900267 scopus 로고    scopus 로고
    • Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells
    • Lu Y, Thomson JM, Wong HY, Hammond SM, Hogan BL. 2007. Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol 310: 442-453.
    • (2007) Dev Biol , vol.310 , pp. 442-453
    • Lu, Y.1    Thomson, J.M.2    Wong, H.Y.3    Hammond, S.M.4    Hogan, B.L.5
  • 122
    • 55249124589 scopus 로고    scopus 로고
    • Epstein-Barr virus-induced miR-155 attenuates NF-κB signaling and stabilizes latent virus persistance
    • Lu F, Weidmer A, Liu CG, Volinia S, Croce CM, Lieberman PM. 2008. Epstein-Barr virus-induced miR-155 attenuates NF-κB signaling and stabilizes latent virus persistance. J Virol 82: 10436-10443.
    • (2008) J Virol , vol.82 , pp. 10436-10443
    • Lu, F.1    Weidmer, A.2    Liu, C.G.3    Volinia, S.4    Croce, C.M.5    Lieberman, P.M.6
  • 124
    • 34447134869 scopus 로고    scopus 로고
    • Patterns of known and novel small RNAs in human cervical cancer
    • Lui WO, Pourmand N, Patterson BK, Fire A. 2007. Patterns of known and novel small RNAs in human cervical cancer. Cancer Res 67: 6031-6043.
    • (2007) Cancer Res , vol.67 , pp. 6031-6043
    • Lui, W.O.1    Pourmand, N.2    Patterson, B.K.3    Fire, A.4
  • 128
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L, Teruya-Feldstein J, Weiberg RA. 2007. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449: 682-688.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weiberg, R.A.3
  • 129
    • 54049115558 scopus 로고    scopus 로고
    • Prognostic value of mature microRNA-21 and microRNA-205 overexpression in nonsmall cell lung cancer by quantitative real-time RT-PCR
    • Markou A, Tsaroucha EG, Kaklamanis L, Fotinou M, Georgoulias V, Lianidou E. 2008. Prognostic value of mature microRNA-21 and microRNA-205 overexpression in nonsmall cell lung cancer by quantitative real-time RT-PCR. Clin Chem 4: 1696-1704.
    • (2008) Clin Chem , vol.4 , pp. 1696-1704
    • Markou, A.1    Tsaroucha, E.G.2    Kaklamanis, L.3    Fotinou, M.4    Georgoulias, V.5    Lianidou, E.6
  • 130
    • 36849026128 scopus 로고    scopus 로고
    • Applications of RNA interference in mammalian systems
    • Martin SE, Caplen NJ. 2007. Applications of RNA interference in mammalian systems. Annu Rev Genomics Hum Genet 8: 81-90.
    • (2007) Annu Rev Genomics Hum Genet , vol.8 , pp. 81-90
    • Martin, S.E.1    Caplen, N.J.2
  • 134
    • 35848963863 scopus 로고    scopus 로고
    • Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition
    • Mejlvang J, Kriajevska M, Vandewalle C, Chernova T, Savan AE, Berx G, Mellon JK, Tulchinsky E. 2007. Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition. Mol Biol Cell 18: 4615-4624.
    • (2007) Mol Biol Cell , vol.18 , pp. 4615-4624
    • Mejlvang, J.1    Kriajevska, M.2    Vandewalle, C.3    Chernova, T.4    Savan, A.E.5    Berx, G.6    Mellon, J.K.7    Tulchinsky, E.8
  • 136
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. 2007. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647-658.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 139
    • 34548059198 scopus 로고    scopus 로고
    • Mishra PJ, Humeniuk R, Mishra PJ, Long-Sorbello GS, Banerjee D, Bertino JR. 2007. A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance. Proc Natl Acad Sci 14: 13513-13518.
    • Mishra PJ, Humeniuk R, Mishra PJ, Long-Sorbello GS, Banerjee D, Bertino JR. 2007. A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance. Proc Natl Acad Sci 14: 13513-13518.
  • 140
    • 38949168082 scopus 로고    scopus 로고
    • Down-regulation of miR-138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines
    • Mitomo S, Maesawa C, Ogasawara S, Iwaya T, Shibazaki M, Yashima-Abo A, Kotani K, Oikawa H, Sakurai E, Izutsu N, et al. 2008. Down-regulation of miR-138 is associated with overexpression of human telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines. Cancer Sci 99: 280-286.
    • (2008) Cancer Sci , vol.99 , pp. 280-286
    • Mitomo, S.1    Maesawa, C.2    Ogasawara, S.3    Iwaya, T.4    Shibazaki, M.5    Yashima-Abo, A.6    Kotani, K.7    Oikawa, H.8    Sakurai, E.9    Izutsu, N.10
  • 141
    • 27744527486 scopus 로고    scopus 로고
    • The first molecular details of ALT in human tumor cells
    • Muntoni A, Redder RR. 2005. The first molecular details of ALT in human tumor cells. Hum Mol Genet 14: R191-R196.
    • (2005) Hum Mol Genet , vol.14
    • Muntoni, A.1    Redder, R.R.2
  • 142
    • 57749089758 scopus 로고    scopus 로고
    • Down-regulation of microRNA-1 (miR-1) in lung cancer: Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin induced apoptosis by miR-1
    • Nasser MW, Datta J, Nuovo G, Kutay H, Motiwala T, Majumber S, Wang B, Suster S, Jacob ST, Ghoshal K. 2008. Down-regulation of microRNA-1 (miR-1) in lung cancer: Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin induced apoptosis by miR-1. J Biol Chem 283: 33394-33405.
    • (2008) J Biol Chem , vol.283 , pp. 33394-33405
    • Nasser, M.W.1    Datta, J.2    Nuovo, G.3    Kutay, H.4    Motiwala, T.5    Majumber, S.6    Wang, B.7    Suster, S.8    Jacob, S.T.9    Ghoshal, K.10
  • 145
    • 33750853059 scopus 로고    scopus 로고
    • Expression of artificial microRNAs in transgenic Arabidopsis thaliana confers virus resistance
    • Niu QW, Lin SS, Reyes JL, Chen KC, Wu HW, Yeh SD, Chua NH. 2006. Expression of artificial microRNAs in transgenic Arabidopsis thaliana confers virus resistance. Nat Biotechnol 24: 1420-1428.
    • (2006) Nat Biotechnol , vol.24 , pp. 1420-1428
    • Niu, Q.W.1    Lin, S.S.2    Reyes, J.L.3    Chen, K.C.4    Wu, H.W.5    Yeh, S.D.6    Chua, N.H.7
  • 146
    • 35348870930 scopus 로고    scopus 로고
    • Upregulation of Twist induces angiogenesis and correlates with metastasis in hepatocellular carcinoma
    • Niu RF, Zhang L, Xi GM, Wei XY, Yang Y, Shi YR, Hao XS. 2007. Upregulation of Twist induces angiogenesis and correlates with metastasis in hepatocellular carcinoma. J Exp Clin Cancer Res 26: 385-394.
    • (2007) J Exp Clin Cancer Res , vol.26 , pp. 385-394
    • Niu, R.F.1    Zhang, L.2    Xi, G.M.3    Wei, X.Y.4    Yang, Y.5    Shi, Y.R.6    Hao, X.S.7
  • 148
    • 34447107760 scopus 로고    scopus 로고
    • The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
    • Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC. 2007. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 130: 89-100.
    • (2007) Cell , vol.130 , pp. 89-100
    • Okamura, K.1    Hagen, J.W.2    Duan, H.3    Tyler, D.M.4    Lai, E.C.5
  • 149
    • 36349012607 scopus 로고    scopus 로고
    • Genome-scale microRNA and small interfering RNA screens identify small RNA modulators of TRAIL-induced apoptosis pathway
    • Ovcharenko D, Kelnar K, Johnson C, Leng N, Brown D. 2007. Genome-scale microRNA and small interfering RNA screens identify small RNA modulators of TRAIL-induced apoptosis pathway. Cancer Res 67: 10782-10788.
    • (2007) Cancer Res , vol.67 , pp. 10782-10788
    • Ovcharenko, D.1    Kelnar, K.2    Johnson, C.3    Leng, N.4    Brown, D.5
  • 151
    • 34249810892 scopus 로고    scopus 로고
    • Argonaute proteins: Mediators of RNA silencing
    • Peters L, Meister G. 2007. Argonaute proteins: Mediators of RNA silencing. Mol Cell 26: 611-623.
    • (2007) Mol Cell , vol.26 , pp. 611-623
    • Peters, L.1    Meister, G.2
  • 152
    • 0037140761 scopus 로고    scopus 로고
    • Locked nucleic acid (LNA) recognition of RNA: NMR solution structures of LNA:RNA hybrids
    • Petersen M, Bondensgaard K, Wengel J, Jacobsen JP. 2002. Locked nucleic acid (LNA) recognition of RNA: NMR solution structures of LNA:RNA hybrids. J Am Chem Soc 124: 5974-5982.
    • (2002) J Am Chem Soc , vol.124 , pp. 5974-5982
    • Petersen, M.1    Bondensgaard, K.2    Wengel, J.3    Jacobsen, J.P.4
  • 154
    • 33749512418 scopus 로고    scopus 로고
    • Viruses, microRNAs, and cancer
    • Pfeffer S, Voinnet O. 2006. Viruses, microRNAs, and cancer. Oncogene 25: 6211-6219.
    • (2006) Oncogene , vol.25 , pp. 6211-6219
    • Pfeffer, S.1    Voinnet, O.2
  • 158
    • 40349094597 scopus 로고    scopus 로고
    • MicroRNA-373 induces expression of genes with complementary promoter sequences
    • Place RF, Li LC, Pookot D, Noonan EJ, Dahiya R. 2008. MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci 105: 1608-1613.
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 1608-1613
    • Place, R.F.1    Li, L.C.2    Pookot, D.3    Noonan, E.J.4    Dahiya, R.5
  • 161
    • 5144225452 scopus 로고    scopus 로고
    • Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity
    • Rand TA, Ginalski K, Grishin NV, Wang X. 2004. Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity. Proc Natl Acad Sci 101: 14385-14398.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 14385-14398
    • Rand, T.A.1    Ginalski, K.2    Grishin, N.V.3    Wang, X.4
  • 163
    • 0029124902 scopus 로고
    • Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: Identification of three independent regions
    • Rasio D, Negrini M, Manenti G, Dragani TA, Croce CM. 1995. Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: Identification of three independent regions. Cancer Res 55: 3988-3991.
    • (1995) Cancer Res , vol.55 , pp. 3988-3991
    • Rasio, D.1    Negrini, M.2    Manenti, G.3    Dragani, T.A.4    Croce, C.M.5
  • 167
    • 33750600178 scopus 로고    scopus 로고
    • MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
    • Roldo C, Missiaglia E, Hagan JP, Falconi M, Capelli P, Bersani S, Calin GA, Volinia S, Liu CG, Scarpa A, et al. 2006. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol 24: 4677-4684.
    • (2006) J Clin Oncol , vol.24 , pp. 4677-4684
    • Roldo, C.1    Missiaglia, E.2    Hagan, J.P.3    Falconi, M.4    Capelli, P.5    Bersani, S.6    Calin, G.A.7    Volinia, S.8    Liu, C.G.9    Scarpa, A.10
  • 168
    • 34447097693 scopus 로고    scopus 로고
    • Intronic microRNA precursors that bypass Drosha processing
    • Ruby JG, Jan CH, Bartel DP. 2007. Intronic microRNA precursors that bypass Drosha processing. Nature 448: 83-86.
    • (2007) Nature , vol.448 , pp. 83-86
    • Ruby, J.G.1    Jan, C.H.2    Bartel, D.P.3
  • 172
    • 33847738628 scopus 로고    scopus 로고
    • Coordinate suppression of ERBB2 and ERBB3 by enforced expression of microRNA miR-125a or miR-125b
    • Scott GK, Goga A, Bhaumik D, Berger CE, Sullivan CS, Benz CC. 2007. Coordinate suppression of ERBB2 and ERBB3 by enforced expression of microRNA miR-125a or miR-125b. J Biol Chem 282: 1479-1486.
    • (2007) J Biol Chem , vol.282 , pp. 1479-1486
    • Scott, G.K.1    Goga, A.2    Bhaumik, D.3    Berger, C.E.4    Sullivan, C.S.5    Benz, C.C.6
  • 174
    • 41549152081 scopus 로고    scopus 로고
    • Mammalian microRNA prediction through a support vector machine model of sequence and structure
    • doi: 10.1371/journal.pone. 0000946
    • Sheng Y, Engström PG, Lenhard B. 2007. Mammalian microRNA prediction through a support vector machine model of sequence and structure. PLoS One 2: e946. doi: 10.1371/journal.pone. 0000946.
    • (2007) PLoS One , vol.2
    • Sheng, Y.1    Engström, P.G.2    Lenhard, B.3
  • 175
    • 34547727263 scopus 로고    scopus 로고
    • Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3′ untranslated region: A mechanism for functional single-nucleotide polymorphisms related to phenotypes
    • Sethupathy P, Borel C, Gagnebin M, Grant GR, Deutsch S, Elton TS, Hatzigeorgiou AS, Antonarakis SE. 2007. Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3′ untranslated region: A mechanism for functional single-nucleotide polymorphisms related to phenotypes. Am J Hum Genet 81: 405-413.
    • (2007) Am J Hum Genet , vol.81 , pp. 405-413
    • Sethupathy, P.1    Borel, C.2    Gagnebin, M.3    Grant, G.R.4    Deutsch, S.5    Elton, T.S.6    Hatzigeorgiou, A.S.7    Antonarakis, S.E.8
  • 179
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of argonaute and its implications for RISC slicer activity
    • Song JJ, Smith SK, Hannon GJ, Joshua-Tor L. 2004. Crystal structure of argonaute and its implications for RISC slicer activity. Science 305: 1434-1437.
    • (2004) Science , vol.305 , pp. 1434-1437
    • Song, J.J.1    Smith, S.K.2    Hannon, G.J.3    Joshua-Tor, L.4
  • 181
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
    • Takamizawa J, Konishi H, Yanagisawa K, Tomida S, Osada H, Endoh H, et al. 2004. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 64: 3753-3756.
    • (2004) Cancer Res , vol.64 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3    Tomida, S.4    Osada, H.5    Endoh, H.6
  • 185
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: MiR-34a is a p53 target that induces apoptosis and G1-arrest
    • Tarasov V, Jung P, Verdoodt B, Lodygin D, Epanchintsev A, Menssen A, Meister G, Hermeking H. 2007. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 6: 1586-1593.
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3    Lodygin, D.4    Epanchintsev, A.5    Menssen, A.6    Meister, G.7    Hermeking, H.8
  • 187
    • 34848868157 scopus 로고    scopus 로고
    • Tumor-suppressor miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
    • Tazawa H, Tsuchiya N, Izumiya M, Nakagama H. 2007. Tumor-suppressor miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci 104: 15472-15477.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 15472-15477
    • Tazawa, H.1    Tsuchiya, N.2    Izumiya, M.3    Nakagama, H.4
  • 188
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP. 2002. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2: 442-454.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 191
    • 16544365954 scopus 로고    scopus 로고
    • Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes
    • doi: 10.1093/nar/gnh171
    • Válóczi A, Hornyik C, Varga N, Burgyán J, Kauppinen S, Havelda Z. 2004. Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes. Nucleic Acids Res 32: e175. doi: 10.1093/nar/gnh171.
    • (2004) Nucleic Acids Res , vol.32
    • Válóczi, A.1    Hornyik, C.2    Varga, N.3    Burgyán, J.4    Kauppinen, S.5    Havelda, Z.6
  • 192
    • 36749026906 scopus 로고    scopus 로고
    • Switching form repression to activation: MicroRNAs can up-regulate translation
    • Vasudevan S, Tong Y, Steitz JA. 2007. Switching form repression to activation: MicroRNAs can up-regulate translation. Science 318: 1931-1934.
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 197
    • 38749095507 scopus 로고    scopus 로고
    • The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of β-site amyloid precursor protein-cleaving enzyme 1
    • Wang WX, Rajeev BW, Stromberg AJ, Ren N, Tang G, Huang Q, Rigoutsos I, Nelson PT. 2008b. The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of β-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 28: 1213-1223.
    • (2008) J Neurosci , vol.28 , pp. 1213-1223
    • Wang, W.X.1    Rajeev, B.W.2    Stromberg, A.J.3    Ren, N.4    Tang, G.5    Huang, Q.6    Rigoutsos, I.7    Nelson, P.T.8
  • 198
    • 0042972556 scopus 로고    scopus 로고
    • Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis
    • Watnick RS, Cheng YN, Rangarajan A, Ince TA, Weinberg RA. 2003. Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell 3: 219-231.
    • (2003) Cancer Cell , vol.3 , pp. 219-231
    • Watnick, R.S.1    Cheng, Y.N.2    Rangarajan, A.3    Ince, T.A.4    Weinberg, R.A.5
  • 200
    • 34249812122 scopus 로고    scopus 로고
    • MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
    • Welch C, Chen Y, Stalling RL. 2007. MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 26: 5017-5022.
    • (2007) Oncogene , vol.26 , pp. 5017-5022
    • Welch, C.1    Chen, Y.2    Stalling, R.L.3
  • 201
    • 52049121293 scopus 로고    scopus 로고
    • Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue
    • Wong TS, Liu XB, Wong BY, Ng RW, Yuen AP, Wei WI. 2008. Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue. Clin Cancer Res 14: 2588-2592.
    • (2008) Clin Cancer Res , vol.14 , pp. 2588-2592
    • Wong, T.S.1    Liu, X.B.2    Wong, B.Y.3    Ng, R.W.4    Yuen, A.P.5    Wei, W.I.6
  • 202
    • 34948829119 scopus 로고    scopus 로고
    • The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes
    • Xu C, Lu Y, Pan Z, Chu W, Luo X, Lin H, Xiao J, Shan H, Wang Z, Yang B. 2007. The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. J Cell Sci 120: 3045-3052.
    • (2007) J Cell Sci , vol.120 , pp. 3045-3052
    • Xu, C.1    Lu, Y.2    Pan, Z.3    Chu, W.4    Luo, X.5    Lin, H.6    Xiao, J.7    Shan, H.8    Wang, Z.9    Yang, B.10
  • 205
    • 15744391012 scopus 로고    scopus 로고
    • Dicer is required for embryonic angiogenesis during mouse development
    • Yang WJ, Yang DD, Na S, Sandusky GE, Zhang Q, Zhao G. 2005. Dicer is required for embryonic angiogenesis during mouse development. J Biol Chem 280: 9330-9335.
    • (2005) J Biol Chem , vol.280 , pp. 9330-9335
    • Yang, W.J.1    Yang, D.D.2    Na, S.3    Sandusky, G.E.4    Zhang, Q.5    Zhao, G.6
  • 206
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi R, Qin Y, Macara IG, Cullen BR. 2003. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes & Dev 17: 3011-3016.
    • (2003) Genes & Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 208
    • 24644446398 scopus 로고    scopus 로고
    • Ribo-gnome: The big world of small RNAs
    • Zamore PD, Haley B. 2005. Ribo-gnome: The big world of small RNAs. Science 309: 1519-1524.
    • (2005) Science , vol.309 , pp. 1519-1524
    • Zamore, P.D.1    Haley, B.2
  • 210
    • 33749236251 scopus 로고    scopus 로고
    • MicroRNA: A new player in stem cells
    • Zhang B, Pan X, Anderson TA. 2006a. MicroRNA: A new player in stem cells. J Cell Physiol 209: 266-269.
    • (2006) J Cell Physiol , vol.209 , pp. 266-269
    • Zhang, B.1    Pan, X.2    Anderson, T.A.3
  • 212
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Zhang B, Pan X, Cobb GP, Anderson TA. 2007a. MicroRNAs as oncogenes and tumor suppressors. Dev Biol 302: 1-12.
    • (2007) Dev Biol , vol.302 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 213
  • 214
    • 57649174634 scopus 로고    scopus 로고
    • MicroRNA-221/222 negatively regulates ERα and associates with tamoxifen resistance in breast cancer
    • Zhao JJ, Lin J, Yang H, Kong W, He L, Ma X, Coppola D, Cheng JQ. 2008. MicroRNA-221/222 negatively regulates ERα and associates with tamoxifen resistance in breast cancer. J Biol Chem 283: 31079-31086.
    • (2008) J Biol Chem , vol.283 , pp. 31079-31086
    • Zhao, J.J.1    Lin, J.2    Yang, H.3    Kong, W.4    He, L.5    Ma, X.6    Coppola, D.7    Cheng, J.Q.8
  • 215
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • Zhu S, Si ML, Wu H, Mo YY. 2007. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem 282: 14328-14336.
    • (2007) J Biol Chem , vol.282 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3    Mo, Y.Y.4
  • 216
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
    • Zhu S, Wu H, Wu F, Nie D, Sheng S, Mo YY. 2008. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 18: 350-359.
    • (2008) Cell Res , vol.18 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3    Nie, D.4    Sheng, S.5    Mo, Y.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.