-
1
-
-
33750726077
-
Clinical features of metastatic bone disease and risk of skeletal morbidity
-
17062708
-
Coleman RE (2006) Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res 12:6243s-6249s
-
(2006)
Clin Cancer Res
, vol.12
-
-
Coleman, R.E.1
-
2
-
-
33748937854
-
Dormancy of solitary metastatic cells
-
1:CAS:528:DC%2BD28Xht1Gnt7rO 16861927
-
Townson JL, Chambers AF (2006) Dormancy of solitary metastatic cells. Cell Cycle 5:1744-1750
-
(2006)
Cell Cycle
, vol.5
, pp. 1744-1750
-
-
Townson, J.L.1
Chambers, A.F.2
-
3
-
-
0038360798
-
Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo
-
1:CAS:528:DC%2BD3sXksVKktLc%3D 12761880
-
Sun YX, Wang J, Shelburne CE, Lopatin DE, Chinnaiyan AM, Rubin MA, Pienta KJ, Taichman RS (2003) Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo. J Cell Biochem 89:462-473
-
(2003)
J Cell Biochem
, vol.89
, pp. 462-473
-
-
Sun, Y.X.1
Wang, J.2
Shelburne, C.E.3
Lopatin, D.E.4
Chinnaiyan, A.M.5
Rubin, M.A.6
Pienta, K.J.7
Taichman, R.S.8
-
4
-
-
13244269963
-
The importance of the CXCL12-CXCR4 chemokine ligand-receptor interaction in prostate cancer metastasis
-
1:CAS:528:DC%2BD2MXhvFOitrg%3D 15844659
-
Arya M, Patel HR, McGurk C, Tatoud R, Klocker H, Masters J, Williamson M (2004) The importance of the CXCL12-CXCR4 chemokine ligand-receptor interaction in prostate cancer metastasis. J Exp Ther Oncol 4:291-303
-
(2004)
J Exp Ther Oncol
, vol.4
, pp. 291-303
-
-
Arya, M.1
Patel, H.R.2
McGurk, C.3
Tatoud, R.4
Klocker, H.5
Masters, J.6
Williamson, M.7
-
5
-
-
19944433608
-
Skeletal localization and neutralization of the SDF-1 (CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo
-
1:CAS:528:DC%2BD2MXhsFars7w%3D 15647826
-
Sun YX, Schneider A, Jung Y, Wang J, Dai J, Wang J, Cook K, Osman NI, Koh-Paige AJ, Shim H, Pienta KJ, Keller ET, McCauley LK, Taichman RS (2005) Skeletal localization and neutralization of the SDF-1 (CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo. J Bone Miner Res 20:318-329
-
(2005)
J Bone Miner Res
, vol.20
, pp. 318-329
-
-
Sun, Y.X.1
Schneider, A.2
Jung, Y.3
Wang, J.4
Dai, J.5
Wang, J.6
Cook, K.7
Osman, N.I.8
Koh-Paige, A.J.9
Shim, H.10
Pienta, K.J.11
Keller, E.T.12
McCauley, L.K.13
Taichman, R.S.14
-
6
-
-
42949133032
-
The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer
-
1:CAS:528:DC%2BD1cXhs1WgtbY%3D 18057003
-
Wang J, Shiozawa Y, Wang J, Wang Y, Jung Y, Pienta KJ, Mehra R, Loberg R, Taichman RS (2008) The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer. J Biol Chem 283:4283-4294
-
(2008)
J Biol Chem
, vol.283
, pp. 4283-4294
-
-
Wang, J.1
Shiozawa, Y.2
Wang, J.3
Wang, Y.4
Jung, Y.5
Pienta, K.J.6
Mehra, R.7
Loberg, R.8
Taichman, R.S.9
-
7
-
-
33644789290
-
Stromal cell derived factor-1: Its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer
-
1:CAS:528:DC%2BD2MXkt1Cjsrg%3D 1175055 15987445
-
Kang H, Watkins G, Parr C, Douglas-Jones A, Mansel RE, Jiang WG (2005) Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer. Breast Cancer Res 7:R402-R410
-
(2005)
Breast Cancer Res
, vol.7
-
-
Kang, H.1
Watkins, G.2
Parr, C.3
Douglas-Jones, A.4
Mansel, R.E.5
Jiang, W.G.6
-
8
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
1:CAS:528:DC%2BD3sXltlSmsL4%3D 12842083
-
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordon-Cardo C, Guise TA, Massague J (2003) A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3:537-549
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordon-Cardo, C.6
Guise, T.A.7
Massague, J.8
-
9
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
1:CAS:528:DC%2BD3MXhvVSgu74%3D 11242036
-
Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, McClanahan T, Murphy E, Yuan W, Wagner SN, Barrera JL, Mohar A, Verastegui E, Zlotnik A (2001) Involvement of chemokine receptors in breast cancer metastasis. Nature 410:50-56
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
McClanahan, T.7
Murphy, E.8
Yuan, W.9
Wagner, S.N.10
Barrera, J.L.11
Mohar, A.12
Verastegui, E.13
Zlotnik, A.14
-
10
-
-
33644529120
-
Clinical significance of chemokine receptor (CCR1, CCR2 and CXCR4) expression in human myeloma cells: The association with disease activity and survival
-
1:CAS:528:DC%2BD28XisFWrsLw%3D 16461304
-
Vande Broek I, Leleu X, Schots R, Facon T, Vanderkerken K, Van Camp B, Van Riet I (2006) Clinical significance of chemokine receptor (CCR1, CCR2 and CXCR4) expression in human myeloma cells: the association with disease activity and survival. Haematologica 91:200-206
-
(2006)
Haematologica
, vol.91
, pp. 200-206
-
-
Vande Broek, I.1
Leleu, X.2
Schots, R.3
Facon, T.4
Vanderkerken, K.5
Van Camp, B.6
Van Riet, I.7
-
11
-
-
20144388592
-
Elevated serum levels of stromal-derived factor-1alpha are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients
-
1:CAS:528:DC%2BD2MXitVOjsLw%3D 15753365
-
Zannettino AC, Farrugia AN, Kortesidis A, Manavis J, To LB, Martin SK, Diamond P, Tamamura H, Lapidot T, Fujii N, Gronthos S (2005) Elevated serum levels of stromal-derived factor-1alpha are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients. Cancer Res 65:1700-1709
-
(2005)
Cancer Res
, vol.65
, pp. 1700-1709
-
-
Zannettino, A.C.1
Farrugia, A.N.2
Kortesidis, A.3
Manavis, J.4
To, L.B.5
Martin, S.K.6
Diamond, P.7
Tamamura, H.8
Lapidot, T.9
Fujii, N.10
Gronthos, S.11
-
12
-
-
33751190044
-
Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: A study in the 5TMM model
-
1:CAS:528:DC%2BD2sXhtVOhurY%3D 17086356
-
Menu E, De Leenheer E, De Raeve H, Coulton L, Imanishi T, Miyashita K, Van Valckenborgh E, Van Riet I, Van Camp B, Horuk R, Croucher P, Vanderkerken K (2006) Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model. Clin Exp Metastasis 23:291-300
-
(2006)
Clin Exp Metastasis
, vol.23
, pp. 291-300
-
-
Menu, E.1
De Leenheer, E.2
De Raeve, H.3
Coulton, L.4
Imanishi, T.5
Miyashita, K.6
Van Valckenborgh, E.7
Van Riet, I.8
Van Camp, B.9
Horuk, R.10
Croucher, P.11
Vanderkerken, K.12
-
13
-
-
34347400986
-
Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation
-
1:CAS:528:DC%2BD2sXnsVais7s%3D 17360942
-
Jung Y, Wang J, Song J, Shiozawa Y, Wang J, Havens A, Wang Z, Sun YX, Emerson SG, Krebsbach PH, Taichman RS (2007) Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation. Blood 110:82-90
-
(2007)
Blood
, vol.110
, pp. 82-90
-
-
Jung, Y.1
Wang, J.2
Song, J.3
Shiozawa, Y.4
Wang, J.5
Havens, A.6
Wang, Z.7
Sun, Y.X.8
Emerson, S.G.9
Krebsbach, P.H.10
Taichman, R.S.11
-
14
-
-
53949112969
-
Annexin II/annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer
-
1:CAS:528:DC%2BD1cXht1elu7rE 3614912 18636554
-
Shiozawa Y, Havens AM, Jung Y, Ziegler AM, Pedersen EA, Wang J, Wang J, Lu G, Roodman GD, Loberg RD, Pienta KJ, Taichman RS (2008) Annexin II/annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer. J Cell Biochem 105:370-380
-
(2008)
J Cell Biochem
, vol.105
, pp. 370-380
-
-
Shiozawa, Y.1
Havens, A.M.2
Jung, Y.3
Ziegler, A.M.4
Pedersen, E.A.5
Wang, J.6
Wang, J.7
Lu, G.8
Roodman, G.D.9
Loberg, R.D.10
Pienta, K.J.11
Taichman, R.S.12
-
15
-
-
51049112515
-
Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone
-
1:CAS:528:DC%2BD1cXptVWntb0%3D 18575746
-
Tamura D, Hiraga T, Myoui A, Yoshikawa H, Yoneda T (2008) Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone. Int J Oncol 33:17-24
-
(2008)
Int J Oncol
, vol.33
, pp. 17-24
-
-
Tamura, D.1
Hiraga, T.2
Myoui, A.3
Yoshikawa, H.4
Yoneda, T.5
-
16
-
-
84893774542
-
Inhibition of cell adhesion by an anti-cadherin 11 antibody prevents bone metastasis
-
Lee YC, Bilen MA, Yu G, Lin SC, Huang CF, Ortiz A, Cho H, Song JH, Satcher RL, Kuang J, Gallick GE, Yu-Lee LY, Huang W, Lin SH (2013) Inhibition of cell adhesion by an anti-cadherin 11 antibody prevents bone metastasis. Mol Cancer Res 29(8):430-435
-
(2013)
Mol Cancer Res
, vol.29
, Issue.8
, pp. 430-435
-
-
Lee, Y.C.1
Bilen, M.A.2
Yu, G.3
Lin, S.C.4
Huang, C.F.5
Ortiz, A.6
Cho, H.7
Song, J.H.8
Satcher, R.L.9
Kuang, J.10
Gallick, G.E.11
Yu-Lee, L.Y.12
Huang, W.13
Lin, S.H.14
-
17
-
-
0037096898
-
Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer
-
1:CAS:528:DC%2BD38XkslWqsb0%3D 12067984
-
Rudland PS, Platt-Higgins A, El-Tanani M, De Silva Rudland S, Barraclough R, Winstanley JH, Howitt R, West CR (2002) Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer. Cancer Res 62:3417-3427
-
(2002)
Cancer Res
, vol.62
, pp. 3417-3427
-
-
Rudland, P.S.1
Platt-Higgins, A.2
El-Tanani, M.3
De Silva, R.S.4
Barraclough, R.5
Winstanley, J.H.6
Howitt, R.7
West, C.R.8
-
18
-
-
0032784057
-
Osteopontin: Possible role in prostate cancer progression
-
1:CAS:528:DyaK1MXlvVOgsrs%3D 10473115
-
Thalmann GN, Sikes RA, Devoll RE, Kiefer JA, Markwalder R, Klima I, Farach-Carson CM, Studer UE, Chung LW (1999) Osteopontin: possible role in prostate cancer progression. Clin Cancer Res 5:2271-2277
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2271-2277
-
-
Thalmann, G.N.1
Sikes, R.A.2
Devoll, R.E.3
Kiefer, J.A.4
Markwalder, R.5
Klima, I.6
Farach-Carson, C.M.7
Studer, U.E.8
Chung, L.W.9
-
19
-
-
21344474104
-
Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells
-
1:CAS:528:DC%2BD2MXosVejsbk%3D 15845900
-
Nilsson SK, Johnston HM, Whitty GA, Williams B, Webb RJ, Denhardt DT, Bertoncello I, Bendall LJ, Simmons PJ, Haylock DN (2005) Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood 106:1232-1239
-
(2005)
Blood
, vol.106
, pp. 1232-1239
-
-
Nilsson, S.K.1
Johnston, H.M.2
Whitty, G.A.3
Williams, B.4
Webb, R.J.5
Denhardt, D.T.6
Bertoncello, I.7
Bendall, L.J.8
Simmons, P.J.9
Haylock, D.N.10
-
20
-
-
84863338444
-
Disseminated prostate cancer cells can instruct hematopoietic stem and progenitor cells to regulate bone phenotype
-
1:CAS:528:DC%2BC38XktVamsrs%3D 3307952 22241219
-
Joseph J, Shiozawa Y, Jung Y, Kim JK, Pedersen E, Mishra A, Zalucha JL, Wang J, Keller ET, Pienta KJ, Taichman RS (2012) Disseminated prostate cancer cells can instruct hematopoietic stem and progenitor cells to regulate bone phenotype. Mol Cancer Res 10:282-292
-
(2012)
Mol Cancer Res
, vol.10
, pp. 282-292
-
-
Joseph, J.1
Shiozawa, Y.2
Jung, Y.3
Kim, J.K.4
Pedersen, E.5
Mishra, A.6
Zalucha, J.L.7
Wang, J.8
Keller, E.T.9
Pienta, K.J.10
Taichman, R.S.11
-
21
-
-
79953331206
-
Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow
-
1:CAS:528:DC%2BC3MXksFahsrw%3D 3069764 21436587
-
Shiozawa Y, Pedersen EA, Havens AM, Jung Y, Mishra A, Joseph J, Kim JK, Patel LR, Ying C, Ziegler AM, Pienta MJ, Song J, Wang J, Loberg RD, Krebsbach PH, Pienta KJ, Taichman RS (2011) Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow. J Clin Invest 121:1298-1312
-
(2011)
J Clin Invest
, vol.121
, pp. 1298-1312
-
-
Shiozawa, Y.1
Pedersen, E.A.2
Havens, A.M.3
Jung, Y.4
Mishra, A.5
Joseph, J.6
Kim, J.K.7
Patel, L.R.8
Ying, C.9
Ziegler, A.M.10
Pienta, M.J.11
Song, J.12
Wang, J.13
Loberg, R.D.14
Krebsbach, P.H.15
Pienta, K.J.16
Taichman, R.S.17
-
22
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
1:CAS:528:DyaK1cXivVyhtrg%3D 9568710
-
Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, Elliott R, Colombero A, Elliott G, Scully S, Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ (1998) Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93:165-176
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.L.3
Kelley, M.J.4
Dunstan, C.R.5
Burgess, T.6
Elliott, R.7
Colombero, A.8
Elliott, G.9
Scully, S.10
Hsu, H.11
Sullivan, J.12
Hawkins, N.13
Davy, E.14
Capparelli, C.15
Eli, A.16
Qian, Y.X.17
Kaufman, S.18
Sarosi, I.19
Shalhoub, V.20
Senaldi, G.21
Guo, J.22
Delaney, J.23
Boyle, W.J.24
more..
-
23
-
-
12944262423
-
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
-
1:CAS:528:DC%2BD3cXhsFCrsL4%3D 10677500
-
Li J, Sarosi I, Yan XQ, Morony S, Capparelli C, Tan HL, McCabe S, Elliott R, Scully S, Van G, Kaufman S, Juan SC, Sun Y, Tarpley J, Martin L, Christensen K, McCabe J, Kostenuik P, Hsu H, Fletcher F, Dunstan CR, Lacey DL, Boyle WJ (2000) RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc Natl Acad Sci USA 97:1566-1571
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1566-1571
-
-
Li, J.1
Sarosi, I.2
Yan, X.Q.3
Morony, S.4
Capparelli, C.5
Tan, H.L.6
McCabe, S.7
Elliott, R.8
Scully, S.9
Van, G.10
Kaufman, S.11
Juan, S.C.12
Sun, Y.13
Tarpley, J.14
Martin, L.15
Christensen, K.16
McCabe, J.17
Kostenuik, P.18
Hsu, H.19
Fletcher, F.20
Dunstan, C.R.21
Lacey, D.L.22
Boyle, W.J.23
more..
-
24
-
-
28544437394
-
The role of immune cells and inflammatory cytokines in Paget's disease and multiple myeloma
-
1:CAS:528:DC%2BD28Xks1ehsQ%3D%3D 16313353
-
Ehrlich LA, Roodman GD (2005) The role of immune cells and inflammatory cytokines in Paget's disease and multiple myeloma. Immunol Rev 208:252-266
-
(2005)
Immunol Rev
, vol.208
, pp. 252-266
-
-
Ehrlich, L.A.1
Roodman, G.D.2
-
25
-
-
0031005576
-
Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
-
1:CAS:528:DyaK2sXislCgtLc%3D 9108485
-
Simonet WS, Lacey DL, Dunstan CR, Kelley M, Chang MS, Luthy R, Nguyen HQ, Wooden S, Bennett L, Boone T, Shimamoto G, DeRose M, Elliott R, Colombero A, Tan HL, Trail G, Sullivan J, Davy E, Bucay N, Renshaw-Gegg L, Hughes TM, Hill D, Pattison W, Campbell P, Sander S, Van G, Tarpley J, Derby P, Lee R, Boyle WJ (1997) Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 89:309-319
-
(1997)
Cell
, vol.89
, pp. 309-319
-
-
Simonet, W.S.1
Lacey, D.L.2
Dunstan, C.R.3
Kelley, M.4
Chang, M.S.5
Luthy, R.6
Nguyen, H.Q.7
Wooden, S.8
Bennett, L.9
Boone, T.10
Shimamoto, G.11
Derose, M.12
Elliott, R.13
Colombero, A.14
Tan, H.L.15
Trail, G.16
Sullivan, J.17
Davy, E.18
Bucay, N.19
Renshaw-Gegg, L.20
Hughes, T.M.21
Hill, D.22
Pattison, W.23
Campbell, P.24
Sander, S.25
Van, G.26
Tarpley, J.27
Derby, P.28
Lee, R.29
Boyle, W.J.30
more..
-
26
-
-
0033305222
-
Breast cancer cells interact with osteoblasts to support osteoclast formation
-
1:CAS:528:DyaK1MXmtFGru78%3D 10499498
-
Thomas RJ, Guise TA, Yin JJ, Elliott J, Horwood NJ, Martin TJ, Gillespie MT (1999) Breast cancer cells interact with osteoblasts to support osteoclast formation. Endocrinology 140:4451-4458
-
(1999)
Endocrinology
, vol.140
, pp. 4451-4458
-
-
Thomas, R.J.1
Guise, T.A.2
Yin, J.J.3
Elliott, J.4
Horwood, N.J.5
Martin, T.J.6
Gillespie, M.T.7
-
27
-
-
33745821237
-
Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation
-
1:CAS:528:DC%2BD28Xnsl2mtL0%3D 16752412
-
Chen G, Sircar K, Aprikian A, Potti A, Goltzman D, Rabbani SA (2006) Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation. Cancer 107:289-298
-
(2006)
Cancer
, vol.107
, pp. 289-298
-
-
Chen, G.1
Sircar, K.2
Aprikian, A.3
Potti, A.4
Goltzman, D.5
Rabbani, S.A.6
-
28
-
-
0035021176
-
Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone
-
1:CAS:528:DC%2BD3MXjsl2ntr0%3D 209296 11375413
-
Zhang J, Dai J, Qi Y, Lin DL, Smith P, Strayhorn C, Mizokami A, Fu Z, Westman J, Keller ET (2001) Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone. J Clin Invest 107:1235-1244
-
(2001)
J Clin Invest
, vol.107
, pp. 1235-1244
-
-
Zhang, J.1
Dai, J.2
Qi, Y.3
Lin, D.L.4
Smith, P.5
Strayhorn, C.6
Mizokami, A.7
Fu, Z.8
Westman, J.9
Keller, E.T.10
-
29
-
-
35448974577
-
Host-derived RANKL is responsible for osteolysis in a C4-2 human prostate cancer xenograft model of experimental bone metastases
-
2034387 17683568
-
Morrissey C, Kostenuik PL, Brown LG, Vessella RL, Corey E (2007) Host-derived RANKL is responsible for osteolysis in a C4-2 human prostate cancer xenograft model of experimental bone metastases. BMC Cancer 7:148
-
(2007)
BMC Cancer
, vol.7
, pp. 148
-
-
Morrissey, C.1
Kostenuik, P.L.2
Brown, L.G.3
Vessella, R.L.4
Corey, E.5
-
30
-
-
0035895055
-
Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma
-
1:CAS:528:DC%2BD3MXptFOjsbY%3D 11739154
-
Croucher PI, Shipman CM, Lippitt J, Perry M, Asosingh K, Hijzen A, Brabbs AC, van Beek EJ, Holen I, Skerry TM, Dunstan CR, Russell GR, Van Camp B, Vanderkerken K (2001) Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma. Blood 98:3534-3540
-
(2001)
Blood
, vol.98
, pp. 3534-3540
-
-
Croucher, P.I.1
Shipman, C.M.2
Lippitt, J.3
Perry, M.4
Asosingh, K.5
Hijzen, A.6
Brabbs, A.C.7
Van Beek, E.J.8
Holen, I.9
Skerry, T.M.10
Dunstan, C.R.11
Russell, G.R.12
Van Camp, B.13
Vanderkerken, K.14
-
31
-
-
0141482103
-
Receptor activator of nuclear factor-kappaB ligand expression by human myeloma cells mediates osteoclast formation in vitro and correlates with bone destruction in vivo
-
1:CAS:528:DC%2BD3sXntleku7w%3D 14500379
-
Farrugia AN, Atkins GJ, To LB, Pan B, Horvath N, Kostakis P, Findlay DM, Bardy P, Zannettino AC (2003) Receptor activator of nuclear factor-kappaB ligand expression by human myeloma cells mediates osteoclast formation in vitro and correlates with bone destruction in vivo. Cancer Res 63:5438-5445
-
(2003)
Cancer Res
, vol.63
, pp. 5438-5445
-
-
Farrugia, A.N.1
Atkins, G.J.2
To, L.B.3
Pan, B.4
Horvath, N.5
Kostakis, P.6
Findlay, D.M.7
Bardy, P.8
Zannettino, A.C.9
-
32
-
-
0036140071
-
Human bone marrow myeloma cells express RANKL
-
11773196
-
Sezer O, Heider U, Jakob C, Eucker J, Possinger K (2002) Human bone marrow myeloma cells express RANKL. J Clin Oncol 20:353-354
-
(2002)
J Clin Oncol
, vol.20
, pp. 353-354
-
-
Sezer, O.1
Heider, U.2
Jakob, C.3
Eucker, J.4
Possinger, K.5
-
33
-
-
0035949510
-
Multiple myeloma disrupts the TRANCE/osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression
-
1:CAS:528:DC%2BD3MXnt12js7w%3D 11562486
-
Pearse RN, Sordillo EM, Yaccoby S, Wong BR, Liau DF, Colman N, Michaeli J, Epstein J, Choi Y (2001) Multiple myeloma disrupts the TRANCE/osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression. Proc Natl Acad Sci USA 98:11581-11586
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11581-11586
-
-
Pearse, R.N.1
Sordillo, E.M.2
Yaccoby, S.3
Wong, B.R.4
Liau, D.F.5
Colman, N.6
Michaeli, J.7
Epstein, J.8
Choi, Y.9
-
34
-
-
0035895083
-
Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment
-
1:CAS:528:DC%2BD3MXptFOjsbk%3D 11739153
-
Giuliani N, Bataille R, Mancini C, Lazzaretti M, Barille S (2001) Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment. Blood 98:3527-3533
-
(2001)
Blood
, vol.98
, pp. 3527-3533
-
-
Giuliani, N.1
Bataille, R.2
Mancini, C.3
Lazzaretti, M.4
Barille, S.5
-
35
-
-
0037374460
-
Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human myeloma cells
-
1:CAS:528:DC%2BD3sXhs1agtb0%3D 12615702
-
Shipman CM, Croucher PI (2003) Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human myeloma cells. Cancer Res 63:912-916
-
(2003)
Cancer Res
, vol.63
, pp. 912-916
-
-
Shipman, C.M.1
Croucher, P.I.2
-
36
-
-
33846433720
-
An osteoprotegerin-like peptidomimetic inhibits osteoclastic bone resorption and osteolytic bone disease in myeloma
-
1:CAS:528:DC%2BD2sXisFSgtw%3D%3D 17210700
-
Heath DJ, Vanderkerken K, Cheng X, Gallagher O, Prideaux M, Murali R, Croucher PI (2007) An osteoprotegerin-like peptidomimetic inhibits osteoclastic bone resorption and osteolytic bone disease in myeloma. Cancer Res 67:202-208
-
(2007)
Cancer Res
, vol.67
, pp. 202-208
-
-
Heath, D.J.1
Vanderkerken, K.2
Cheng, X.3
Gallagher, O.4
Prideaux, M.5
Murali, R.6
Croucher, P.I.7
-
37
-
-
1542720384
-
Cancer and the microenvironment: Myeloma-osteoclast interactions as a model
-
1:CAS:528:DC%2BD2cXitFCgtb4%3D 15026338
-
Yaccoby S, Wezeman MJ, Henderson A, Cottler-Fox M, Yi Q, Barlogie B, Epstein J (2004) Cancer and the microenvironment: myeloma-osteoclast interactions as a model. Cancer Res 64:2016-2023
-
(2004)
Cancer Res
, vol.64
, pp. 2016-2023
-
-
Yaccoby, S.1
Wezeman, M.J.2
Henderson, A.3
Cottler-Fox, M.4
Yi, Q.5
Barlogie, B.6
Epstein, J.7
-
38
-
-
41149094679
-
Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis
-
1:CAS:528:DC%2BD1cXmtFyhtbs%3D 18064531
-
Canon JR, Roudier M, Bryant R, Morony S, Stolina M, Kostenuik PJ, Dougall WC (2008) Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis. Clin Exp Metastasis 25:119-129
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 119-129
-
-
Canon, J.R.1
Roudier, M.2
Bryant, R.3
Morony, S.4
Stolina, M.5
Kostenuik, P.J.6
Dougall, W.C.7
-
39
-
-
77953726348
-
Combined therapy with the RANKL inhibitor RANK-Fc and rhApo2L/TRAIL/dulanermin reduces bone lesions and skeletal tumor burden in a model of breast cancer skeletal metastasis
-
1:CAS:528:DC%2BC3cXhtVGksLnE 20150760
-
Holland PM, Miller R, Jones J, Douangpanya H, Piasecki J, Roudier M, Dougall WC (2010) Combined therapy with the RANKL inhibitor RANK-Fc and rhApo2L/TRAIL/dulanermin reduces bone lesions and skeletal tumor burden in a model of breast cancer skeletal metastasis. Cancer Biol Ther 9:539-550
-
(2010)
Cancer Biol Ther
, vol.9
, pp. 539-550
-
-
Holland, P.M.1
Miller, R.2
Jones, J.3
Douangpanya, H.4
Piasecki, J.5
Roudier, M.6
Dougall, W.C.7
-
40
-
-
51049121618
-
RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis
-
1:CAS:528:DC%2BD1cXoslCnsrw%3D 18606716
-
Miller RE, Roudier M, Jones J, Armstrong A, Canon J, Dougall WC (2008) RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis. Mol Cancer Ther 7:2160-2169
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2160-2169
-
-
Miller, R.E.1
Roudier, M.2
Jones, J.3
Armstrong, A.4
Canon, J.5
Dougall, W.C.6
-
41
-
-
35348897212
-
Randomized active-controlled phase II study of denosumab efficacy and safety in patients with breast cancer-related bone metastases
-
1:CAS:528:DC%2BD2sXht1ertrjP 17785705
-
Lipton A, Steger GG, Figueroa J, Alvarado C, Solal-Celigny P, Body JJ, de Boer R, Berardi R, Gascon P, Tonkin KS, Coleman R, Paterson AH, Peterson MC, Fan M, Kinsey A, Jun S (2007) Randomized active-controlled phase II study of denosumab efficacy and safety in patients with breast cancer-related bone metastases. J Clin Oncol 25:4431-4437
-
(2007)
J Clin Oncol
, vol.25
, pp. 4431-4437
-
-
Lipton, A.1
Steger, G.G.2
Figueroa, J.3
Alvarado, C.4
Solal-Celigny, P.5
Body, J.J.6
De Boer, R.7
Berardi, R.8
Gascon, P.9
Tonkin, K.S.10
Coleman, R.11
Paterson, A.H.12
Peterson, M.C.13
Fan, M.14
Kinsey, A.15
Jun, S.16
-
42
-
-
63749094012
-
Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates
-
1:CAS:528:DC%2BD1MXltVOhtr0%3D 19237632
-
Fizazi K, Lipton A, Mariette X, Body JJ, Rahim Y, Gralow JR, Gao G, Wu L, Sohn W, Jun S (2009) Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. J Clin Oncol 27:1564-1571
-
(2009)
J Clin Oncol
, vol.27
, pp. 1564-1571
-
-
Fizazi, K.1
Lipton, A.2
Mariette, X.3
Body, J.J.4
Rahim, Y.5
Gralow, J.R.6
Gao, G.7
Wu, L.8
Sohn, W.9
Jun, S.10
-
43
-
-
33846169078
-
Skeletal metastasis: Established and emerging roles of parathyroid hormone related protein (PTHrP)
-
1:CAS:528:DC%2BD2sXisVyrtg%3D%3D 17165129
-
Liao J, McCauley LK (2006) Skeletal metastasis: established and emerging roles of parathyroid hormone related protein (PTHrP). Cancer Metastasis Rev 25:559-571
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 559-571
-
-
Liao, J.1
McCauley, L.K.2
-
44
-
-
0030861712
-
Parathyroid hormone-related protein and bone metastases
-
1:CAS:528:DyaK2sXmvFyht7w%3D 9362424
-
Guise TA (1997) Parathyroid hormone-related protein and bone metastases. Cancer 80:1572-1580
-
(1997)
Cancer
, vol.80
, pp. 1572-1580
-
-
Guise, T.A.1
-
45
-
-
0025821071
-
Localization of parathyroid hormone-related protein in breast cancer metastases: Increased incidence in bone compared with other sites
-
1:STN:280:DyaK3M3jsFaiuw%3D%3D 2032246
-
Powell GJ, Southby J, Danks JA, Stillwell RG, Hayman JA, Henderson MA, Bennett RC, Martin TJ (1991) Localization of parathyroid hormone-related protein in breast cancer metastases: increased incidence in bone compared with other sites. Cancer Res 51:3059-3061
-
(1991)
Cancer Res
, vol.51
, pp. 3059-3061
-
-
Powell, G.J.1
Southby, J.2
Danks, J.A.3
Stillwell, R.G.4
Hayman, J.A.5
Henderson, M.A.6
Bennett, R.C.7
Martin, T.J.8
-
46
-
-
10144241022
-
Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis
-
1:CAS:528:DyaK28XmtVCmu70%3D 507586 8833902
-
Guise TA, Yin JJ, Taylor SD, Kumagai Y, Dallas M, Boyce BF, Yoneda T, Mundy GR (1996) Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. J Clin Invest 98:1544-1549
-
(1996)
J Clin Invest
, vol.98
, pp. 1544-1549
-
-
Guise, T.A.1
Yin, J.J.2
Taylor, S.D.3
Kumagai, Y.4
Dallas, M.5
Boyce, B.F.6
Yoneda, T.7
Mundy, G.R.8
-
47
-
-
79551514021
-
TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling
-
1:CAS:528:DC%2BC3MXhsVCisbg%3D 3077118 21189326
-
Johnson RW, Nguyen MP, Padalecki SS, Grubbs BG, Merkel AR, Oyajobi BO, Matrisian LM, Mundy GR, Sterling JA (2011) TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling. Cancer Res 71:822-831
-
(2011)
Cancer Res
, vol.71
, pp. 822-831
-
-
Johnson, R.W.1
Nguyen, M.P.2
Padalecki, S.S.3
Grubbs, B.G.4
Merkel, A.R.5
Oyajobi, B.O.6
Matrisian, L.M.7
Mundy, G.R.8
Sterling, J.A.9
-
48
-
-
0033305046
-
Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: Correlation with osteoclast-like cell formation
-
1:CAS:528:DyaK1MXkslKru74%3D 10433211
-
Lee SK, Lorenzo JA (1999) Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation. Endocrinology 140:3552-3561
-
(1999)
Endocrinology
, vol.140
, pp. 3552-3561
-
-
Lee, S.K.1
Lorenzo, J.A.2
-
49
-
-
0036472717
-
Parathyroid hormone related peptide and receptor expression in paired primary prostate cancer and bone metastases
-
1:CAS:528:DC%2BD38XisFOlsrs%3D 2375222 11875691
-
Bryden AA, Hoyland JA, Freemont AJ, Clarke NW, George NJ (2002) Parathyroid hormone related peptide and receptor expression in paired primary prostate cancer and bone metastases. Br J Cancer 86:322-325
-
(2002)
Br J Cancer
, vol.86
, pp. 322-325
-
-
Bryden, A.A.1
Hoyland, J.A.2
Freemont, A.J.3
Clarke, N.W.4
George, N.J.5
-
50
-
-
84876196796
-
A phase 2 multicentre study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with relapsed or refractory multiple myeloma
-
1:CAS:528:DC%2BC3sXlvVensrg%3D
-
Voorhees PM, Manges RF, Sonneveld P, Jagannath S, Somlo G, Krishnan A, Lentzsch S, Frank RC, Zweegman S, Wijermans PW, Orlowski RZ, Kranenburg B, Hall B, Casneuf T, Qin X, van de Velde H, Xie H, Thomas SK (2013) A phase 2 multicentre study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with relapsed or refractory multiple myeloma. British J Haematol 161:357-366
-
(2013)
British J Haematol
, vol.161
, pp. 357-366
-
-
Voorhees, P.M.1
Manges, R.F.2
Sonneveld, P.3
Jagannath, S.4
Somlo, G.5
Krishnan, A.6
Lentzsch, S.7
Frank, R.C.8
Zweegman, S.9
Wijermans, P.W.10
Orlowski, R.Z.11
Kranenburg, B.12
Hall, B.13
Casneuf, T.14
Qin, X.15
Van De Velde, H.16
Xie, H.17
Thomas, S.K.18
-
52
-
-
0037105542
-
IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappaB in mouse calvariae
-
1:CAS:528:DC%2BD38XntFags70%3D 12218157
-
Palmqvist P, Persson E, Conaway HH, Lerner UH (2002) IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappaB in mouse calvariae. J Immunol 169:3353-3362
-
(2002)
J Immunol
, vol.169
, pp. 3353-3362
-
-
Palmqvist, P.1
Persson, E.2
Conaway, H.H.3
Lerner, U.H.4
-
53
-
-
0033921535
-
Immunohistochemical localization of interleukin-6 and its receptor in benign, premalignant and malignant prostate tissue
-
1:CAS:528:DC%2BD3cXltlygsrk%3D 10878544
-
Hobisch A, Rogatsch H, Hittmair A, Fuchs D, Bartsch G Jr, Klocker H, Bartsch G, Culig Z (2000) Immunohistochemical localization of interleukin-6 and its receptor in benign, premalignant and malignant prostate tissue. J Pathol 191:239-244
-
(2000)
J Pathol
, vol.191
, pp. 239-244
-
-
Hobisch, A.1
Rogatsch, H.2
Hittmair, A.3
Fuchs, D.4
Bartsch, Jr.G.5
Klocker, H.6
Bartsch, G.7
Culig, Z.8
-
54
-
-
0025677214
-
Expression of the interleukin 6 receptor and interleukin 6 in prostate carcinoma cells
-
1:CAS:528:DyaK3MXit1agtw%3D%3D 2253221
-
Siegall CB, Schwab G, Nordan RP, FitzGerald DJ, Pastan I (1990) Expression of the interleukin 6 receptor and interleukin 6 in prostate carcinoma cells. Cancer Res 50:7786-7788
-
(1990)
Cancer Res
, vol.50
, pp. 7786-7788
-
-
Siegall, C.B.1
Schwab, G.2
Nordan, R.P.3
Fitzgerald, D.J.4
Pastan, I.5
-
55
-
-
10744227424
-
CYP2C and IL-6 expression in breast cancer
-
1:STN:280:DC%2BD2c%2FlvVGjtw%3D%3D 14759713
-
Knupfer H, Schmidt R, Stanitz D, Brauckhoff M, Schonfelder M, Preiss R (2004) CYP2C and IL-6 expression in breast cancer. Breast 13:28-34
-
(2004)
Breast
, vol.13
, pp. 28-34
-
-
Knupfer, H.1
Schmidt, R.2
Stanitz, D.3
Brauckhoff, M.4
Schonfelder, M.5
Preiss, R.6
-
56
-
-
36549049974
-
Metastatic breast cancer induces an osteoblast inflammatory response
-
1:CAS:528:DC%2BD2sXhtlyrtrvE 17976581
-
Kinder M, Chislock E, Bussard KM, Shuman L, Mastro AM (2008) Metastatic breast cancer induces an osteoblast inflammatory response. Exp Cell Res 314:173-183
-
(2008)
Exp Cell Res
, vol.314
, pp. 173-183
-
-
Kinder, M.1
Chislock, E.2
Bussard, K.M.3
Shuman, L.4
Mastro, A.M.5
-
57
-
-
79751472667
-
Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
-
1:CAS:528:DC%2BC3MXhvFeksbo%3D 3040415 21295524
-
Sethi N, Dai X, Winter CG, Kang Y (2011) Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell 19:192-205
-
(2011)
Cancer Cell
, vol.19
, pp. 192-205
-
-
Sethi, N.1
Dai, X.2
Winter, C.G.3
Kang, Y.4
-
58
-
-
0037114636
-
Human myeloma cells stimulate the receptor activator of nuclear factor-kappa B ligand (RANKL) in T lymphocytes: A potential role in multiple myeloma bone disease
-
1:CAS:528:DC%2BD38XpsFCqt78%3D 12393684
-
Giuliani N, Colla S, Sala R, Moroni M, Lazzaretti M, La Monica S, Bonomini S, Hojden M, Sammarelli G, Barille S, Bataille R, Rizzoli V (2002) Human myeloma cells stimulate the receptor activator of nuclear factor-kappa B ligand (RANKL) in T lymphocytes: a potential role in multiple myeloma bone disease. Blood 100:4615-4621
-
(2002)
Blood
, vol.100
, pp. 4615-4621
-
-
Giuliani, N.1
Colla, S.2
Sala, R.3
Moroni, M.4
Lazzaretti, M.5
La Monica, S.6
Bonomini, S.7
Hojden, M.8
Sammarelli, G.9
Barille, S.10
Bataille, R.11
Rizzoli, V.12
-
59
-
-
23744498205
-
Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation
-
1:CAS:528:DC%2BD2MXhtVKqt73K 15933061
-
Giuliani N, Colla S, Morandi F, Lazzaretti M, Sala R, Bonomini S, Grano M, Colucci S, Svaldi M, Rizzoli V (2005) Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation. Blood 106:2472-2483
-
(2005)
Blood
, vol.106
, pp. 2472-2483
-
-
Giuliani, N.1
Colla, S.2
Morandi, F.3
Lazzaretti, M.4
Sala, R.5
Bonomini, S.6
Grano, M.7
Colucci, S.8
Svaldi, M.9
Rizzoli, V.10
-
60
-
-
0042707678
-
Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease
-
1:CAS:528:DC%2BD3sXmt1KjsLw%3D 12919697
-
Bendre MS, Montague DC, Peery T, Akel NS, Gaddy D, Suva LJ (2003) Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease. Bone 33:28-37
-
(2003)
Bone
, vol.33
, pp. 28-37
-
-
Bendre, M.S.1
Montague, D.C.2
Peery, T.3
Akel, N.S.4
Gaddy, D.5
Suva, L.J.6
-
61
-
-
77954194855
-
Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-kappaB activity in myeloma cells
-
3095250 20604947
-
Markovina S, Callander NS, O'Connor SL, Xu G, Shi Y, Leith CP, Kim K, Trivedi P, Kim J, Hematti P, Miyamoto S (2010) Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-kappaB activity in myeloma cells. Mol Cancer 9:176
-
(2010)
Mol Cancer
, vol.9
, pp. 176
-
-
Markovina, S.1
Callander, N.S.2
O'Connor, S.L.3
Xu, G.4
Shi, Y.5
Leith, C.P.6
Kim, K.7
Trivedi, P.8
Kim, J.9
Hematti, P.10
Miyamoto, S.11
-
62
-
-
18144383028
-
Stromal cell-derived factor-1 binding to its chemokine receptor CXCR4 on precursor cells promotes the chemotactic recruitment, development and survival of human osteoclasts
-
1:CAS:528:DC%2BD2MXjvVOisbw%3D 15794931
-
Wright LM, Maloney W, Yu X, Kindle L, Collin-Osdoby P, Osdoby P (2005) Stromal cell-derived factor-1 binding to its chemokine receptor CXCR4 on precursor cells promotes the chemotactic recruitment, development and survival of human osteoclasts. Bone 36:840-853
-
(2005)
Bone
, vol.36
, pp. 840-853
-
-
Wright, L.M.1
Maloney, W.2
Yu, X.3
Kindle, L.4
Collin-Osdoby, P.5
Osdoby, P.6
-
63
-
-
0035383761
-
Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand
-
1:CAS:528:DC%2BD3MXktFOkt7o%3D 11369623
-
Han JH, Choi SJ, Kurihara N, Koide M, Oba Y, Roodman GD (2001) Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand. Blood 97:3349-3353
-
(2001)
Blood
, vol.97
, pp. 3349-3353
-
-
Han, J.H.1
Choi, S.J.2
Kurihara, N.3
Koide, M.4
Oba, Y.5
Roodman, G.D.6
-
64
-
-
0037105599
-
Role for macrophage inflammatory protein (MIP)-1alpha and MIP-1beta in the development of osteolytic lesions in multiple myeloma
-
1:CAS:528:DC%2BD38Xnt1yhsb4%3D 12200385
-
Abe M, Hiura K, Wilde J, Moriyama K, Hashimoto T, Ozaki S, Wakatsuki S, Kosaka M, Kido S, Inoue D, Matsumoto T (2002) Role for macrophage inflammatory protein (MIP)-1alpha and MIP-1beta in the development of osteolytic lesions in multiple myeloma. Blood 100:2195-2202
-
(2002)
Blood
, vol.100
, pp. 2195-2202
-
-
Abe, M.1
Hiura, K.2
Wilde, J.3
Moriyama, K.4
Hashimoto, T.5
Ozaki, S.6
Wakatsuki, S.7
Kosaka, M.8
Kido, S.9
Inoue, D.10
Matsumoto, T.11
-
65
-
-
0038579121
-
Dual effects of macrophage inflammatory protein-1alpha on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease
-
1:CAS:528:DC%2BD3sXltFelsrw%3D 12649140
-
Oyajobi BO, Franchin G, Williams PJ, Pulkrabek D, Gupta A, Munoz S, Grubbs B, Zhao M, Chen D, Sherry B, Mundy GR (2003) Dual effects of macrophage inflammatory protein-1alpha on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease. Blood 102:311-319
-
(2003)
Blood
, vol.102
, pp. 311-319
-
-
Oyajobi, B.O.1
Franchin, G.2
Williams, P.J.3
Pulkrabek, D.4
Gupta, A.5
Munoz, S.6
Grubbs, B.7
Zhao, M.8
Chen, D.9
Sherry, B.10
Mundy, G.R.11
-
66
-
-
34548689594
-
The mouse mammary carcinoma 4T1: Characterization of the cellular landscape of primary tumors and metastatic tumor foci
-
1:CAS:528:DC%2BD2sXht1WmsL7F 2517332 17877537
-
DuPre SA, Redelman D, Hunter KW Jr (2007) The mouse mammary carcinoma 4T1: characterization of the cellular landscape of primary tumors and metastatic tumor foci. Int J Exp Pathol 88:351-360
-
(2007)
Int J Exp Pathol
, vol.88
, pp. 351-360
-
-
Dupre, S.A.1
Redelman, D.2
Hunter, Jr.K.W.3
-
67
-
-
0034194652
-
Integrins and signaling in osteoclast function
-
1:CAS:528:DC%2BD3cXkt1aqu74%3D 10842093
-
Duong LT, Lakkakorpi P, Nakamura I, Rodan GA (2000) Integrins and signaling in osteoclast function. Matrix Biol 19:97-105
-
(2000)
Matrix Biol
, vol.19
, pp. 97-105
-
-
Duong, L.T.1
Lakkakorpi, P.2
Nakamura, I.3
Rodan, G.A.4
-
68
-
-
83455208311
-
VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging alpha4beta1-positive osteoclast progenitors
-
1:CAS:528:DC%2BC3MXhs1Cit77P 3241854 22137794
-
Lu X, Mu E, Wei Y, Riethdorf S, Yang Q, Yuan M, Yan J, Hua Y, Tiede BJ, Lu X, Haffty BG, Pantel K, Massague J, Kang Y (2011) VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging alpha4beta1-positive osteoclast progenitors. Cancer Cell 20:701-714
-
(2011)
Cancer Cell
, vol.20
, pp. 701-714
-
-
Lu, X.1
Mu, E.2
Wei, Y.3
Riethdorf, S.4
Yang, Q.5
Yuan, M.6
Yan, J.7
Hua, Y.8
Tiede, B.J.9
Lu, X.10
Haffty, B.G.11
Pantel, K.12
Massague, J.13
Kang, Y.14
-
69
-
-
77951709842
-
Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface
-
1:CAS:528:DC%2BC3cXltlegu7c%3D 2862120 20406980
-
Nannuru KC, Futakuchi M, Varney ML, Vincent TM, Marcusson EG, Singh RK (2010) Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface. Cancer Res 70:3494-3504
-
(2010)
Cancer Res
, vol.70
, pp. 3494-3504
-
-
Nannuru, K.C.1
Futakuchi, M.2
Varney, M.L.3
Vincent, T.M.4
Marcusson, E.G.5
Singh, R.K.6
-
70
-
-
34447324943
-
Prostate cancer-associated membrane type 1-matrix metalloproteinase: A pivotal role in bone response and intraosseous tumor growth
-
1:CAS:528:DC%2BD2sXntlOhtbo%3D 17525276
-
Bonfil RD, Dong Z, Trindade Filho JC, Sabbota A, Osenkowski P, Nabha S, Yamamoto H, Chinni SR, Zhao H, Mobashery S, Vessella RL, Fridman R, Cher ML (2007) Prostate cancer-associated membrane type 1-matrix metalloproteinase: a pivotal role in bone response and intraosseous tumor growth. Am J Pathol 170:2100-2111
-
(2007)
Am J Pathol
, vol.170
, pp. 2100-2111
-
-
Bonfil, R.D.1
Dong, Z.2
Trindade Filho, J.C.3
Sabbota, A.4
Osenkowski, P.5
Nabha, S.6
Yamamoto, H.7
Chinni, S.R.8
Zhao, H.9
Mobashery, S.10
Vessella, R.L.11
Fridman, R.12
Cher, M.L.13
-
71
-
-
78650304107
-
Matrix metalloproteinases as master regulators of the vicious cycle of bone metastasis
-
1:CAS:528:DC%2BC3cXhs1Wgu7rI 20601294
-
Lynch CC (2011) Matrix metalloproteinases as master regulators of the vicious cycle of bone metastasis. Bone 48:44-53
-
(2011)
Bone
, vol.48
, pp. 44-53
-
-
Lynch, C.C.1
-
72
-
-
69249094919
-
Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis
-
1:CAS:528:DC%2BD1MXpvFeju7c%3D 2745595 19679556
-
Thiolloy S, Halpern J, Holt GE, Schwartz HS, Mundy GR, Matrisian LM, Lynch CC (2009) Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis. Cancer Res 69:6747-6755
-
(2009)
Cancer Res
, vol.69
, pp. 6747-6755
-
-
Thiolloy, S.1
Halpern, J.2
Holt, G.E.3
Schwartz, H.S.4
Mundy, G.R.5
Matrisian, L.M.6
Lynch, C.C.7
-
73
-
-
84876768839
-
Circulating levels of transforming growth factor-beta (TGF-beta) and chemokine (C-X-C motif) ligand-1 (CXCL1) as predictors of distant seeding of circulating tumor cells in patients with metastatic breast cancer
-
1:CAS:528:DC%2BC3sXntVyitbo%3D 23564790
-
Divella R, Daniele A, Savino E, Palma F, Bellizzi A, Giotta F, Simone G, Lioce M, Quaranta M, Paradiso A, Mazzocca A (2013) Circulating levels of transforming growth factor-beta (TGF-beta) and chemokine (C-X-C motif) ligand-1 (CXCL1) as predictors of distant seeding of circulating tumor cells in patients with metastatic breast cancer. Anticancer Res 33:1491-1497
-
(2013)
Anticancer Res
, vol.33
, pp. 1491-1497
-
-
Divella, R.1
Daniele, A.2
Savino, E.3
Palma, F.4
Bellizzi, A.5
Giotta, F.6
Simone, G.7
Lioce, M.8
Quaranta, M.9
Paradiso, A.10
Mazzocca, A.11
-
74
-
-
33747691662
-
Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression
-
1:CAS:528:DC%2BD28Xot1eqsrY%3D 16815840
-
McMahon S, Charbonneau M, Grandmont S, Richard DE, Dubois CM (2006) Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression. J Biol Chem 281:24171-24181
-
(2006)
J Biol Chem
, vol.281
, pp. 24171-24181
-
-
McMahon, S.1
Charbonneau, M.2
Grandmont, S.3
Richard, D.E.4
Dubois, C.M.5
-
75
-
-
84865206098
-
Intravenous administration of adenoviruses targeting transforming growth factor beta signaling inhibits established bone metastases in 4T1 mouse mammary tumor model in an immunocompetent syngeneic host
-
1:CAS:528:DC%2BC38XpsVWitb0%3D 3424293 22744210
-
Zhang Z, Hu Z, Gupta J, Krimmel JD, Gerseny HM, Berg AF, Robbins JS, Du H, Prabhakar B, Seth P (2012) Intravenous administration of adenoviruses targeting transforming growth factor beta signaling inhibits established bone metastases in 4T1 mouse mammary tumor model in an immunocompetent syngeneic host. Cancer Gene Ther 19:630-636
-
(2012)
Cancer Gene Ther
, vol.19
, pp. 630-636
-
-
Zhang, Z.1
Hu, Z.2
Gupta, J.3
Krimmel, J.D.4
Gerseny, H.M.5
Berg, A.F.6
Robbins, J.S.7
Du, H.8
Prabhakar, B.9
Seth, P.10
-
76
-
-
28144433008
-
Influence of BMPs on the formation of osteoblastic lesions in metastatic prostate cancer
-
1:CAS:528:DC%2BD2MXhtlWntrbL 16294272
-
Feeley BT, Gamradt SC, Hsu WK, Liu N, Krenek L, Robbins P, Huard J, Lieberman JR (2005) Influence of BMPs on the formation of osteoblastic lesions in metastatic prostate cancer. J Bone Miner Res 20:2189-2199
-
(2005)
J Bone Miner Res
, vol.20
, pp. 2189-2199
-
-
Feeley, B.T.1
Gamradt, S.C.2
Hsu, W.K.3
Liu, N.4
Krenek, L.5
Robbins, P.6
Huard, J.7
Lieberman, J.R.8
-
77
-
-
0029422455
-
Bone morphogenetic protein-6 expression in normal and malignant prostate
-
1:STN:280:DyaK2s%2FmtlGjsg%3D%3D 9116752
-
Barnes J, Anthony CT, Wall N, Steiner MS (1995) Bone morphogenetic protein-6 expression in normal and malignant prostate. World J Urol 13:337-343
-
(1995)
World J Urol
, vol.13
, pp. 337-343
-
-
Barnes, J.1
Anthony, C.T.2
Wall, N.3
Steiner, M.S.4
-
78
-
-
79960960617
-
BMP4 promotes prostate tumor growth in bone through osteogenesis
-
1:CAS:528:DC%2BC3MXpsVOhurc%3D 3148283 21670081
-
Lee YC, Cheng CJ, Bilen MA, Lu JF, Satcher RL, Yu-Lee LY, Gallick GE, Maity SN, Lin SH (2011) BMP4 promotes prostate tumor growth in bone through osteogenesis. Cancer Res 71:5194-5203
-
(2011)
Cancer Res
, vol.71
, pp. 5194-5203
-
-
Lee, Y.C.1
Cheng, C.J.2
Bilen, M.A.3
Lu, J.F.4
Satcher, R.L.5
Yu-Lee, L.Y.6
Gallick, G.E.7
Maity, S.N.8
Lin, S.H.9
-
79
-
-
24944480253
-
Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism
-
1:CAS:528:DC%2BD2MXhtVShsbjK 16166304
-
Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller ET (2005) Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res 65:8274-8285
-
(2005)
Cancer Res
, vol.65
, pp. 8274-8285
-
-
Dai, J.1
Keller, J.2
Zhang, J.3
Lu, Y.4
Yao, Z.5
Keller, E.T.6
-
80
-
-
70449097998
-
Bone morphogenic protein 6: A member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis
-
1:CAS:528:DC%2BD1MXhtVKhs7zE 2844406 19718049
-
Seckinger A, Meissner T, Moreaux J, Goldschmidt H, Fuhler GM, Benner A, Hundemer M, Reme T, Shaughnessy JD Jr, Barlogie B, Bertsch U, Hillengass J, Ho AD, Pantesco V, Jauch A, De Vos J, Rossi JF, Mohler T, Klein B, Hose D (2009) Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis. Oncogene 28:3866-3879
-
(2009)
Oncogene
, vol.28
, pp. 3866-3879
-
-
Seckinger, A.1
Meissner, T.2
Moreaux, J.3
Goldschmidt, H.4
Fuhler, G.M.5
Benner, A.6
Hundemer, M.7
Reme, T.8
Shaughnessy, Jr.J.D.9
Barlogie, B.10
Bertsch, U.11
Hillengass, J.12
Ho, A.D.13
Pantesco, V.14
Jauch, A.15
De Vos, J.16
Rossi, J.F.17
Mohler, T.18
Klein, B.19
Hose, D.20
more..
-
81
-
-
33847025382
-
Lack of noggin expression by cancer cells is a determinant of the osteoblast response in bone metastases
-
1:CAS:528:DC%2BD2sXhsV2gurg%3D 17200191
-
Schwaninger R, Rentsch CA, Wetterwald A, van der Horst G, van Bezooijen RL, van der Pluijm G, Lowik CW, Ackermann K, Pyerin W, Hamdy FC, Thalmann GN, Cecchini MG (2007) Lack of noggin expression by cancer cells is a determinant of the osteoblast response in bone metastases. Am J Pathol 170:160-175
-
(2007)
Am J Pathol
, vol.170
, pp. 160-175
-
-
Schwaninger, R.1
Rentsch, C.A.2
Wetterwald, A.3
Van Der Horst, G.4
Van Bezooijen, R.L.5
Van Der Pluijm, G.6
Lowik, C.W.7
Ackermann, K.8
Pyerin, W.9
Hamdy, F.C.10
Thalmann, G.N.11
Cecchini, M.G.12
-
82
-
-
67449094018
-
Loss of inhibition over master pathways of bone mass regulation results in osteosclerotic bone metastases in prostate cancer
-
1:STN:280:DC%2BD1MzisVanuw%3D%3D
-
Rentsch CA, Cecchini MG, Thalmann GN (2009) Loss of inhibition over master pathways of bone mass regulation results in osteosclerotic bone metastases in prostate cancer. Swiss Med Weekly 139:220-225
-
(2009)
Swiss Med Weekly
, vol.139
, pp. 220-225
-
-
Rentsch, C.A.1
Cecchini, M.G.2
Thalmann, G.N.3
-
83
-
-
79251571488
-
The role of the BMP signaling antagonist noggin in the development of prostate cancer osteolytic bone metastasis
-
1:CAS:528:DC%2BC3MXhtFWnsLk%3D 3020964 21249149
-
Secondini C, Wetterwald A, Schwaninger R, Thalmann GN, Cecchini MG (2011) The role of the BMP signaling antagonist noggin in the development of prostate cancer osteolytic bone metastasis. PloS One 6:e16078
-
(2011)
PloS One
, vol.6
, pp. 16078
-
-
Secondini, C.1
Wetterwald, A.2
Schwaninger, R.3
Thalmann, G.N.4
Cecchini, M.G.5
-
84
-
-
35348921682
-
Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment
-
1:CAS:528:DC%2BD2sXht1KqsbbK 17956733
-
Sacchetti B, Funari A, Michienzi S, Di Cesare S, Piersanti S, Saggio I, Tagliafico E, Ferrari S, Robey PG, Riminucci M, Bianco P (2007) Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 131:324-336
-
(2007)
Cell
, vol.131
, pp. 324-336
-
-
Sacchetti, B.1
Funari, A.2
Michienzi, S.3
Di Cesare, S.4
Piersanti, S.5
Saggio, I.6
Tagliafico, E.7
Ferrari, S.8
Robey, P.G.9
Riminucci, M.10
Bianco, P.11
-
85
-
-
33748954261
-
Activin A circulating levels in patients with bone metastasis from breast or prostate cancer
-
1:CAS:528:DC%2BD2sXitFCgtg%3D%3D 16841234
-
Leto G, Incorvaia L, Badalamenti G, Tumminello FM, Gebbia N, Flandina C, Crescimanno M, Rini G (2006) Activin A circulating levels in patients with bone metastasis from breast or prostate cancer. Clin Exp Metastasis 23:117-122
-
(2006)
Clin Exp Metastasis
, vol.23
, pp. 117-122
-
-
Leto, G.1
Incorvaia, L.2
Badalamenti, G.3
Tumminello, F.M.4
Gebbia, N.5
Flandina, C.6
Crescimanno, M.7
Rini, G.8
-
86
-
-
84867135322
-
Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; No alterations post-lenalidomide and dexamethasone therapy
-
1:STN:280:DC%2BC38rktVSquw%3D%3D 22492699
-
Terpos E, Kastritis E, Christoulas D, Gkotzamanidou M, Eleutherakis-Papaiakovou E, Kanellias N, Papatheodorou A, Dimopoulos MA (2012) Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; no alterations post-lenalidomide and dexamethasone therapy. Ann Oncol 23:2681-2686
-
(2012)
Ann Oncol
, vol.23
, pp. 2681-2686
-
-
Terpos, E.1
Kastritis, E.2
Christoulas, D.3
Gkotzamanidou, M.4
Eleutherakis-Papaiakovou, E.5
Kanellias, N.6
Papatheodorou, A.7
Dimopoulos, M.A.8
-
87
-
-
77950438331
-
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease
-
1:CAS:528:DC%2BC3cXjvFGntbw%3D 20194748
-
Vallet S, Mukherjee S, Vaghela N, Hideshima T, Fulciniti M, Pozzi S, Santo L, Cirstea D, Patel K, Sohani AR, Guimaraes A, Xie W, Chauhan D, Schoonmaker JA, Attar E, Churchill M, Weller E, Munshi N, Seehra JS, Weissleder R, Anderson KC, Scadden DT, Raje N (2010) Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease. Proc Natl Acad Sci USA 107:5124-5129
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5124-5129
-
-
Vallet, S.1
Mukherjee, S.2
Vaghela, N.3
Hideshima, T.4
Fulciniti, M.5
Pozzi, S.6
Santo, L.7
Cirstea, D.8
Patel, K.9
Sohani, A.R.10
Guimaraes, A.11
Xie, W.12
Chauhan, D.13
Schoonmaker, J.A.14
Attar, E.15
Churchill, M.16
Weller, E.17
Munshi, N.18
Seehra, J.S.19
Weissleder, R.20
Anderson, K.C.21
Scadden, D.T.22
Raje, N.23
more..
-
88
-
-
69249230778
-
Regulation of osteoblastogenesis and osteoclastogenesis by the other reproductive hormones, activin and inhibin
-
1:CAS:528:DC%2BD1MXhtVKlsr%2FJ 2951729 19615428
-
Nicks KM, Perrien DS, Akel NS, Suva LJ, Gaddy D (2009) Regulation of osteoblastogenesis and osteoclastogenesis by the other reproductive hormones, activin and inhibin. Mol Cell Endocrinol 310:11-20
-
(2009)
Mol Cell Endocrinol
, vol.310
, pp. 11-20
-
-
Nicks, K.M.1
Perrien, D.S.2
Akel, N.S.3
Suva, L.J.4
Gaddy, D.5
-
89
-
-
77957727888
-
Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo
-
20533325
-
Chantry AD, Heath D, Mulivor AW, Pearsall S, Baud'huin M, Coulton L, Evans H, Abdul N, Werner ED, Bouxsein ML, Key ML, Seehra J, Arnett TR, Vanderkerken K, Croucher P (2010) Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo. J Bone Miner Res 25:2633-2646
-
(2010)
J Bone Miner Res
, vol.25
, pp. 2633-2646
-
-
Chantry, A.D.1
Heath, D.2
Mulivor, A.W.3
Pearsall, S.4
Baud'Huin, M.5
Coulton, L.6
Evans, H.7
Abdul, N.8
Werner, E.D.9
Bouxsein, M.L.10
Key, M.L.11
Seehra, J.12
Arnett, T.R.13
Vanderkerken, K.14
Croucher, P.15
-
90
-
-
0346363760
-
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
-
1:CAS:528:DC%2BD3sXhtVWit7zO 14695408
-
Tian E, Zhan F, Walker R, Rasmussen E, Ma Y, Barlogie B, Shaughnessy JD Jr (2003) The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 349:2483-2494
-
(2003)
N Engl J Med
, vol.349
, pp. 2483-2494
-
-
Tian, E.1
Zhan, F.2
Walker, R.3
Rasmussen, E.4
Ma, Y.5
Barlogie, B.6
Shaughnessy, Jr.J.D.7
-
91
-
-
4444326415
-
Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: Potential pathogenetic and prognostic implications
-
1:CAS:528:DC%2BD2cXotFWnsLk%3D 15316903
-
Chen G, Shukeir N, Potti A, Sircar K, Aprikian A, Goltzman D, Rabbani SA (2004) Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications. Cancer 101:1345-1356
-
(2004)
Cancer
, vol.101
, pp. 1345-1356
-
-
Chen, G.1
Shukeir, N.2
Potti, A.3
Sircar, K.4
Aprikian, A.5
Goltzman, D.6
Rabbani, S.A.7
-
92
-
-
33645006198
-
Role of Wnts in prostate cancer bone metastases
-
1:CAS:528:DC%2BD28Xis1Crs7o%3D 16447163
-
Hall CL, Kang S, MacDougald OA, Keller ET (2006) Role of Wnts in prostate cancer bone metastases. J Cell Biochem 97:661-672
-
(2006)
J Cell Biochem
, vol.97
, pp. 661-672
-
-
Hall, C.L.1
Kang, S.2
Macdougald, O.A.3
Keller, E.T.4
-
93
-
-
38549095978
-
Low-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new bone
-
1:CAS:528:DC%2BD1cXhtVKru7g%3D 17700537
-
Li ZG, Yang J, Vazquez ES, Rose D, Vakar-Lopez F, Mathew P, Lopez A, Logothetis CJ, Lin SH, Navone NM (2008) Low-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new bone. Oncogene 27:596-603
-
(2008)
Oncogene
, vol.27
, pp. 596-603
-
-
Li, Z.G.1
Yang, J.2
Vazquez, E.S.3
Rose, D.4
Vakar-Lopez, F.5
Mathew, P.6
Lopez, A.7
Logothetis, C.J.8
Lin, S.H.9
Navone, N.M.10
-
94
-
-
79952403539
-
Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases
-
1:CAS:528:DC%2BC3MXksVKmsr4%3D 3025080 20957670
-
Thudi NK, Martin CK, Murahari S, Shu ST, Lanigan LG, Werbeck JL, Keller ET, McCauley LK, Pinzone JJ, Rosol TJ (2011) Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases. Prostate 71:615-625
-
(2011)
Prostate
, vol.71
, pp. 615-625
-
-
Thudi, N.K.1
Martin, C.K.2
Murahari, S.3
Shu, S.T.4
Lanigan, L.G.5
Werbeck, J.L.6
Keller, E.T.7
McCauley, L.K.8
Pinzone, J.J.9
Rosol, T.J.10
-
95
-
-
24744439747
-
Prostate cancer cells promote osteoblastic bone metastases through Wnts
-
1:CAS:528:DC%2BD2MXpslaitL4%3D 16140917
-
Hall CL, Bafico A, Dai J, Aaronson SA, Keller ET (2005) Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Res 65:7554-7560
-
(2005)
Cancer Res
, vol.65
, pp. 7554-7560
-
-
Hall, C.L.1
Bafico, A.2
Dai, J.3
Aaronson, S.A.4
Keller, E.T.5
-
96
-
-
28544445306
-
Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer
-
1:CAS:528:DC%2BD2MXht1Wgu77F 16288033
-
Joesting MS, Perrin S, Elenbaas B, Fawell SE, Rubin JS, Franco OE, Hayward SW, Cunha GR, Marker PC (2005) Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer. Cancer Res 65:10423-10430
-
(2005)
Cancer Res
, vol.65
, pp. 10423-10430
-
-
Joesting, M.S.1
Perrin, S.2
Elenbaas, B.3
Fawell, S.E.4
Rubin, J.S.5
Franco, O.E.6
Hayward, S.W.7
Cunha, G.R.8
Marker, P.C.9
-
97
-
-
56149084790
-
Osteoclasts are active in bone forming metastases of prostate cancer patients
-
2574033 18978943
-
Roato I, D'Amelio P, Gorassini E, Grimaldi A, Bonello L, Fiori C, Delsedime L, Tizzani A, De Libero A, Isaia G, Ferracini R (2008) Osteoclasts are active in bone forming metastases of prostate cancer patients. PloS One 3:e3627
-
(2008)
PloS One
, vol.3
, pp. 3627
-
-
Roato, I.1
D'Amelio, P.2
Gorassini, E.3
Grimaldi, A.4
Bonello, L.5
Fiori, C.6
Delsedime, L.7
Tizzani, A.8
De Libero, A.9
Isaia, G.10
Ferracini, R.11
-
98
-
-
34948859456
-
Increased Dickkopf-1 expression in breast cancer bone metastases
-
1:CAS:528:DC%2BD2sXhtFSnurfM 2360424 17876334
-
Voorzanger-Rousselot N, Goehrig D, Journe F, Doriath V, Body JJ, Clezardin P, Garnero P (2007) Increased Dickkopf-1 expression in breast cancer bone metastases. Br J Cancer 97:964-970
-
(2007)
Br J Cancer
, vol.97
, pp. 964-970
-
-
Voorzanger-Rousselot, N.1
Goehrig, D.2
Journe, F.3
Doriath, V.4
Body, J.J.5
Clezardin, P.6
Garnero, P.7
-
99
-
-
47249149740
-
Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases
-
1:CAS:528:DC%2BD1cXhtVSrsLvK 3732167 18546262
-
Bu G, Lu W, Liu CC, Selander K, Yoneda T, Hall C, Keller ET, Li Y (2008) Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases. Int J Cancer 123:1034-1042
-
(2008)
Int J Cancer
, vol.123
, pp. 1034-1042
-
-
Bu, G.1
Lu, W.2
Liu, C.C.3
Selander, K.4
Yoneda, T.5
Hall, C.6
Keller, E.T.7
Li, Y.8
-
100
-
-
48649090754
-
Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms
-
1:CAS:528:DC%2BD1cXovVCnsL0%3D 18632632
-
Dai J, Hall CL, Escara-Wilke J, Mizokami A, Keller JM, Keller ET (2008) Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms. Cancer Res 68:5785-5794
-
(2008)
Cancer Res
, vol.68
, pp. 5785-5794
-
-
Dai, J.1
Hall, C.L.2
Escara-Wilke, J.3
Mizokami, A.4
Keller, J.M.5
Keller, E.T.6
-
101
-
-
33747468221
-
Serum concentrations of Dickkopf-1 protein are increased in patients with multiple myeloma and reduced after autologous stem cell transplantation
-
Politou MC, Heath DJ, Rahemtulla A, Szydlo R, Anagnostopoulos A, Dimopoulos MA, Croucher PI, Terpos E (2006) Serum concentrations of Dickkopf-1 protein are increased in patients with multiple myeloma and reduced after autologous stem cell transplantation. Int J Cancer 19:1728-1731
-
(2006)
Int J Cancer
, vol.19
, pp. 1728-1731
-
-
Politou, M.C.1
Heath, D.J.2
Rahemtulla, A.3
Szydlo, R.4
Anagnostopoulos, A.5
Dimopoulos, M.A.6
Croucher, P.I.7
Terpos, E.8
-
102
-
-
34548008809
-
Production of Wnt inhibitors by myeloma cells: Potential effects on canonical Wnt pathway in the bone microenvironment
-
1:CAS:528:DC%2BD2sXptVGlsLY%3D 17702698
-
Giuliani N, Morandi F, Tagliaferri S, Lazzaretti M, Donofrio G, Bonomini S, Sala R, Mangoni M, Rizzoli V (2007) Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment. Cancer Res 67:7665-7674
-
(2007)
Cancer Res
, vol.67
, pp. 7665-7674
-
-
Giuliani, N.1
Morandi, F.2
Tagliaferri, S.3
Lazzaretti, M.4
Donofrio, G.5
Bonomini, S.6
Sala, R.7
Mangoni, M.8
Rizzoli, V.9
-
103
-
-
67650431302
-
Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma
-
1:CAS:528:DC%2BD1MXovVKlsrs%3D 19417213
-
Fulciniti M, Tassone P, Hideshima T, Vallet S, Nanjappa P, Ettenberg SA, Shen Z, Patel N, Tai YT, Chauhan D, Mitsiades C, Prabhala R, Raje N, Anderson KC, Stover DR, Munshi NC (2009) Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma. Blood 114:371-379
-
(2009)
Blood
, vol.114
, pp. 371-379
-
-
Fulciniti, M.1
Tassone, P.2
Hideshima, T.3
Vallet, S.4
Nanjappa, P.5
Ettenberg, S.A.6
Shen, Z.7
Patel, N.8
Tai, Y.T.9
Chauhan, D.10
Mitsiades, C.11
Prabhala, R.12
Raje, N.13
Anderson, K.C.14
Stover, D.R.15
Munshi, N.C.16
-
104
-
-
27644473781
-
Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2
-
1:CAS:528:DC%2BD2MXht1Wntr3K 16030194
-
Oshima T, Abe M, Asano J, Hara T, Kitazoe K, Sekimoto E, Tanaka Y, Shibata H, Hashimoto T, Ozaki S, Kido S, Inoue D, Matsumoto T (2005) Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2. Blood 106:3160-3165
-
(2005)
Blood
, vol.106
, pp. 3160-3165
-
-
Oshima, T.1
Abe, M.2
Asano, J.3
Hara, T.4
Kitazoe, K.5
Sekimoto, E.6
Tanaka, Y.7
Shibata, H.8
Hashimoto, T.9
Ozaki, S.10
Kido, S.11
Inoue, D.12
Matsumoto, T.13
-
105
-
-
40849083276
-
Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma
-
1:CAS:528:DC%2BD1cXjs1Whurk%3D 18294945
-
Qiang YW, Barlogie B, Rudikoff S, Shaughnessy JD Jr (2008) Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma. Bone 42:669-680
-
(2008)
Bone
, vol.42
, pp. 669-680
-
-
Qiang, Y.W.1
Barlogie, B.2
Rudikoff, S.3
Shaughnessy, Jr.J.D.4
-
106
-
-
84860537254
-
Bone marrow stromal cells create a permissive microenvironment for myeloma development: A new stromal role for Wnt inhibitor Dkk1
-
1:CAS:528:DC%2BC38Xmt1ymsLg%3D 3775476 22374979
-
Fowler JA, Mundy GR, Lwin ST, Edwards CM (2012) Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1. Cancer Res 72:2183-2189
-
(2012)
Cancer Res
, vol.72
, pp. 2183-2189
-
-
Fowler, J.A.1
Mundy, G.R.2
Lwin, S.T.3
Edwards, C.M.4
-
107
-
-
79953243181
-
Influencing the Wnt signaling pathway in multiple myeloma
-
1:CAS:528:DC%2BC3MXksFWkt74%3D 21378363
-
Kim Y, Reifenberger G, Lu D, Endo T, Carson DA, Gast SM, Meschenmoser K, Nowak M, Schmidt-Wolf IG (2011) Influencing the Wnt signaling pathway in multiple myeloma. Anticancer Res 31:725-730
-
(2011)
Anticancer Res
, vol.31
, pp. 725-730
-
-
Kim, Y.1
Reifenberger, G.2
Lu, D.3
Endo, T.4
Carson, D.A.5
Gast, S.M.6
Meschenmoser, K.7
Nowak, M.8
Schmidt-Wolf, I.G.9
-
108
-
-
33847397091
-
Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo
-
1:CAS:528:DC%2BD2sXjtFequrY%3D 17068150
-
Yaccoby S, Ling W, Zhan F, Walker R, Barlogie B, Shaughnessy JD Jr (2007) Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo. Blood 109:2106-2111
-
(2007)
Blood
, vol.109
, pp. 2106-2111
-
-
Yaccoby, S.1
Ling, W.2
Zhan, F.3
Walker, R.4
Barlogie, B.5
Shaughnessy, Jr.J.D.6
-
109
-
-
61849137831
-
Inhibiting Dickkopf-1 (Dkk1) removes suppression of bone formation and prevents the development of osteolytic bone disease in multiple myeloma
-
1:CAS:528:DC%2BD1MXjslKru78%3D 19016584
-
Heath DJ, Chantry AD, Buckle CH, Coulton L, Shaughnessy JD Jr, Evans HR, Snowden JA, Stover DR, Vanderkerken K, Croucher PI (2009) Inhibiting Dickkopf-1 (Dkk1) removes suppression of bone formation and prevents the development of osteolytic bone disease in multiple myeloma. J Bone Miner Res 24:425-436
-
(2009)
J Bone Miner Res
, vol.24
, pp. 425-436
-
-
Heath, D.J.1
Chantry, A.D.2
Buckle, C.H.3
Coulton, L.4
Shaughnessy, Jr.J.D.5
Evans, H.R.6
Snowden, J.A.7
Stover, D.R.8
Vanderkerken, K.9
Croucher, P.I.10
-
110
-
-
41949093576
-
Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo
-
1:CAS:528:DC%2BD1cXivFakurs%3D 18094333
-
Edwards CM, Edwards JR, Lwin ST, Esparza J, Oyajobi BO, McCluskey B, Munoz S, Grubbs B, Mundy GR (2008) Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo. Blood 111:2833-2842
-
(2008)
Blood
, vol.111
, pp. 2833-2842
-
-
Edwards, C.M.1
Edwards, J.R.2
Lwin, S.T.3
Esparza, J.4
Oyajobi, B.O.5
McCluskey, B.6
Munoz, S.7
Grubbs, B.8
Mundy, G.R.9
-
111
-
-
84864062016
-
Myeloma cells suppress osteoblasts through sclerostin secretion
-
1:STN:280:DC%2BC38fislKmuw%3D%3D 3255263 22829171
-
Colucci S, Brunetti G, Oranger A, Mori G, Sardone F, Specchia G, Rinaldi E, Curci P, Liso V, Passeri G, Zallone A, Rizzi R, Grano M (2011) Myeloma cells suppress osteoblasts through sclerostin secretion. Blood Cancer J 1:e27
-
(2011)
Blood Cancer J
, vol.1
, pp. 27
-
-
Colucci, S.1
Brunetti, G.2
Oranger, A.3
Mori, G.4
Sardone, F.5
Specchia, G.6
Rinaldi, E.7
Curci, P.8
Liso, V.9
Passeri, G.10
Zallone, A.11
Rizzi, R.12
Grano, M.13
-
112
-
-
84864144433
-
Elevated circulating sclerostin correlates with advanced disease features and abnormal bone remodeling in symptomatic myeloma: Reduction post-bortezomib monotherapy
-
1:CAS:528:DC%2BC3MXhs1CnsrrK 22052418
-
Terpos E, Christoulas D, Katodritou E, Bratengeier C, Gkotzamanidou M, Michalis E, Delimpasi S, Pouli A, Meletis J, Kastritis E, Zervas K, Dimopoulos MA (2012) Elevated circulating sclerostin correlates with advanced disease features and abnormal bone remodeling in symptomatic myeloma: reduction post-bortezomib monotherapy. Int J Cancer 131:1466-1471
-
(2012)
Int J Cancer
, vol.131
, pp. 1466-1471
-
-
Terpos, E.1
Christoulas, D.2
Katodritou, E.3
Bratengeier, C.4
Gkotzamanidou, M.5
Michalis, E.6
Delimpasi, S.7
Pouli, A.8
Meletis, J.9
Kastritis, E.10
Zervas, K.11
Dimopoulos, M.A.12
-
113
-
-
84863959463
-
Sclerostin: A possible target for the management of cancer-induced bone disease
-
1:CAS:528:DC%2BC38XhtVKgu7%2FP 22762409
-
Gkotzamanidou M, Dimopoulos MA, Kastritis E, Christoulas D, Moulopoulos LA, Terpos E (2012) Sclerostin: a possible target for the management of cancer-induced bone disease. Expert Opin Ther Targets 16:761-769
-
(2012)
Expert Opin Ther Targets
, vol.16
, pp. 761-769
-
-
Gkotzamanidou, M.1
Dimopoulos, M.A.2
Kastritis, E.3
Christoulas, D.4
Moulopoulos, L.A.5
Terpos, E.6
-
114
-
-
80054954943
-
Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFbeta-dependent expression of the Wnt antagonist, sclerostin
-
1:CAS:528:DC%2BC38Xms1CmsQ%3D%3D 3262219 22032690
-
Mendoza-Villanueva D, Zeef L, Shore P (2011) Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFbeta-dependent expression of the Wnt antagonist, sclerostin. Breast Cancer Res 13:R106
-
(2011)
Breast Cancer Res
, vol.13
, pp. 106
-
-
Mendoza-Villanueva, D.1
Zeef, L.2
Shore, P.3
-
115
-
-
84880570863
-
Endothelin antagonists in hypertension and kidney disease
-
23070275
-
Meyers KE, Sethna C (2013) Endothelin antagonists in hypertension and kidney disease. Pediatr Nephrol 28:711-720
-
(2013)
Pediatr Nephrol
, vol.28
, pp. 711-720
-
-
Meyers, K.E.1
Sethna, C.2
-
116
-
-
80053214622
-
Regulation of postnatal trabecular bone formation by the osteoblast endothelin A receptor
-
1:CAS:528:DC%2BC3MXht1yitLfN 3183222 21698666
-
Clines GA, Mohammad KS, Grunda JM, Clines KL, Niewolna M, McKenna CR, McKibbin CR, Yanagisawa M, Suva LJ, Chirgwin JM, Guise TA (2011) Regulation of postnatal trabecular bone formation by the osteoblast endothelin A receptor. J Bone Miner Res 26:2523-2536
-
(2011)
J Bone Miner Res
, vol.26
, pp. 2523-2536
-
-
Clines, G.A.1
Mohammad, K.S.2
Grunda, J.M.3
Clines, K.L.4
Niewolna, M.5
McKenna, C.R.6
McKibbin, C.R.7
Yanagisawa, M.8
Suva, L.J.9
Chirgwin, J.M.10
Guise, T.A.11
-
117
-
-
6344266822
-
Endothelins in bone cancer metastases
-
1:CAS:528:DC%2BD2cXnsFOkur8%3D 15043194
-
Guise TA, Mohammad KS (2004) Endothelins in bone cancer metastases. Cancer Treat Res 118:197-212
-
(2004)
Cancer Treat Res
, vol.118
, pp. 197-212
-
-
Guise, T.A.1
Mohammad, K.S.2
-
118
-
-
0029085123
-
Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate
-
1:CAS:528:DyaK2MXnvVyrtb8%3D 7585222
-
Nelson JB, Hedican SP, George DJ, Reddi AH, Piantadosi S, Eisenberger MA, Simons JW (1995) Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat Med 1:944-949
-
(1995)
Nat Med
, vol.1
, pp. 944-949
-
-
Nelson, J.B.1
Hedican, S.P.2
George, D.J.3
Reddi, A.H.4
Piantadosi, S.5
Eisenberger, M.A.6
Simons, J.W.7
-
119
-
-
0141479984
-
A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases
-
1:CAS:528:DC%2BD3sXnslyntbg%3D 12941866
-
Yin JJ, Mohammad KS, Kakonen SM, Harris S, Wu-Wong JR, Wessale JL, Padley RJ, Garrett IR, Chirgwin JM, Guise TA (2003) A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases. Proc Natl Acad Sci USA 100:10954-10959
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10954-10959
-
-
Yin, J.J.1
Mohammad, K.S.2
Kakonen, S.M.3
Harris, S.4
Wu-Wong, J.R.5
Wessale, J.L.6
Padley, R.J.7
Garrett, I.R.8
Chirgwin, J.M.9
Guise, T.A.10
-
120
-
-
35648968713
-
A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer
-
1:CAS:528:DC%2BD2sXhtlertbrP 17886253
-
Carducci MA, Saad F, Abrahamsson PA, Dearnaley DP, Schulman CC, North SA, Sleep DJ, Isaacson JD, Nelson JB, Atrasentan Phase III, Institutions Study Group (2007) A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer. Cancer 110:1959-1966
-
(2007)
Cancer
, vol.110
, pp. 1959-1966
-
-
Carducci, M.A.1
Saad, F.2
Abrahamsson, P.A.3
Dearnaley, D.P.4
Schulman, C.C.5
North, S.A.6
Sleep, D.J.7
Isaacson, J.D.8
Nelson, J.B.9
Atrasentan Phase, I.I.I.10
Institutions, S.G.11
-
121
-
-
62649134676
-
Safety and efficacy of the specific endothelin-A receptor antagonist ZD4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: A double-blind, placebo-controlled, randomised, phase 2 trial
-
1:CAS:528:DC%2BD1MXnvF2qtrk%3D 19042080
-
James ND, Caty A, Borre M, Zonnenberg BA, Beuzeboc P, Morris T, Phung D, Dawson NA (2009) Safety and efficacy of the specific endothelin-A receptor antagonist ZD4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: a double-blind, placebo-controlled, randomised, phase 2 trial. Eur Urol 55:1112-1123
-
(2009)
Eur Urol
, vol.55
, pp. 1112-1123
-
-
James, N.D.1
Caty, A.2
Borre, M.3
Zonnenberg, B.A.4
Beuzeboc, P.5
Morris, T.6
Phung, D.7
Dawson, N.A.8
-
122
-
-
34548570445
-
Rho-kinase regulates endothelin-1-stimulated IL-6 synthesis via p38 MAP kinase in osteoblasts
-
1:CAS:528:DC%2BD2sXhtVGisbfO 17825250
-
Tokuda H, Hanai Y, Matsushima-Nishiwaki R, Yamauchi J, Doi T, Harada A, Takai S, Kozawa O (2007) Rho-kinase regulates endothelin-1-stimulated IL-6 synthesis via p38 MAP kinase in osteoblasts. Biochem Biophys Res Commun 362:799-804
-
(2007)
Biochem Biophys Res Commun
, vol.362
, pp. 799-804
-
-
Tokuda, H.1
Hanai, Y.2
Matsushima-Nishiwaki, R.3
Yamauchi, J.4
Doi, T.5
Harada, A.6
Takai, S.7
Kozawa, O.8
-
123
-
-
0034619758
-
The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization
-
1:CAS:528:DC%2BD3MXhsFCrsw%3D%3D 11146556
-
Ogawa K, Pasqualini R, Lindberg RA, Kain R, Freeman AL, Pasquale EB (2000) The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization. Oncogene 19:6043-6052
-
(2000)
Oncogene
, vol.19
, pp. 6043-6052
-
-
Ogawa, K.1
Pasqualini, R.2
Lindberg, R.A.3
Kain, R.4
Freeman, A.L.5
Pasquale, E.B.6
-
124
-
-
0035266163
-
EphA2 overexpression causes tumorigenesis of mammary epithelial cells
-
1:CAS:528:DC%2BD3MXit1Ogt7k%3D 11280802
-
Zelinski DP, Zantek ND, Stewart JC, Irizarry AR, Kinch MS (2001) EphA2 overexpression causes tumorigenesis of mammary epithelial cells. Cancer Res 61:2301-2306
-
(2001)
Cancer Res
, vol.61
, pp. 2301-2306
-
-
Zelinski, D.P.1
Zantek, N.D.2
Stewart, J.C.3
Irizarry, A.R.4
Kinch, M.S.5
-
125
-
-
67649811207
-
Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis
-
1:CAS:528:DC%2BD1MXlvV2isL8%3D 19299512
-
Irie N, Takada Y, Watanabe Y, Matsuzaki Y, Naruse C, Asano M, Iwakura Y, Suda T, Matsuo K (2009) Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis. J Biol Chem 284:14637-14644
-
(2009)
J Biol Chem
, vol.284
, pp. 14637-14644
-
-
Irie, N.1
Takada, Y.2
Watanabe, Y.3
Matsuzaki, Y.4
Naruse, C.5
Asano, M.6
Iwakura, Y.7
Suda, T.8
Matsuo, K.9
-
126
-
-
70349263942
-
The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth
-
1:CAS:528:DC%2BD1MXhtFWgsbbL 19597185
-
Pennisi A, Ling W, Li X, Khan S, Shaughnessy JD Jr, Barlogie B, Yaccoby S (2009) The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth. Blood 114:1803-1812
-
(2009)
Blood
, vol.114
, pp. 1803-1812
-
-
Pennisi, A.1
Ling, W.2
Li, X.3
Khan, S.4
Shaughnessy, Jr.J.D.5
Barlogie, B.6
Yaccoby, S.7
-
127
-
-
0029039982
-
Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma
-
1:CAS:528:DyaK2MXmtlWrtL4%3D 7780988
-
Coltrera MD, Wang J, Porter PL, Gown AM (1995) Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma. Cancer Res 55:2703-2708
-
(1995)
Cancer Res
, vol.55
, pp. 2703-2708
-
-
Coltrera, M.D.1
Wang, J.2
Porter, P.L.3
Gown, A.M.4
-
128
-
-
0027488086
-
Tissue platelet-derived growth factor (PDGF) predicts for shortened survival and treatment failure in advanced breast cancer
-
1:STN:280:DyaK2c%2Fnt1Ontw%3D%3D 8251649
-
Seymour L, Dajee D, Bezwoda WR (1993) Tissue platelet-derived growth factor (PDGF) predicts for shortened survival and treatment failure in advanced breast cancer. Breast Cancer Res Treat 26:247-252
-
(1993)
Breast Cancer Res Treat
, vol.26
, pp. 247-252
-
-
Seymour, L.1
Dajee, D.2
Bezwoda, W.R.3
-
129
-
-
0001871671
-
Platelet-derived growth factor and the skeleton
-
J.B. Bilezikian L.G. Raisz A. Rodan (eds) Academic Press San Diego, CA
-
Canalis E, Rydziel S (1996) Platelet-derived growth factor and the skeleton. In: Bilezikian JB, Raisz LG, Rodan A (eds) Principles of bone biology. Academic Press, San Diego, CA, pp 619-626
-
(1996)
Principles of Bone Biology
, pp. 619-626
-
-
Canalis, E.1
Rydziel, S.2
-
130
-
-
81355138197
-
Cooperative effects in differentiation and proliferation between PDGF-BB and matrix derived synthetic peptides in human osteoblasts
-
1:CAS:528:DC%2BC38XpvVejtg%3D%3D 3231994 22104124
-
Vordemvenne T, Paletta JR, Hartensuer R, Pap T, Raschke MJ, Ochman S (2011) Cooperative effects in differentiation and proliferation between PDGF-BB and matrix derived synthetic peptides in human osteoblasts. BMC Musculoskelet Disord 12:263
-
(2011)
BMC Musculoskelet Disord
, vol.12
, pp. 263
-
-
Vordemvenne, T.1
Paletta, J.R.2
Hartensuer, R.3
Pap, T.4
Raschke, M.J.5
Ochman, S.6
-
131
-
-
0028807859
-
Platelet-derived growth factor stimulates the synthesis of interleukin-6 in cells of the osteoblast lineage
-
1:CAS:528:DyaK2MXps1Kisrs%3D 7588297
-
Franchimont N, Canalis E (1995) Platelet-derived growth factor stimulates the synthesis of interleukin-6 in cells of the osteoblast lineage. Endocrinology 136:5469-5475
-
(1995)
Endocrinology
, vol.136
, pp. 5469-5475
-
-
Franchimont, N.1
Canalis, E.2
-
132
-
-
81755162058
-
SDF-1alpha induces PDGF-B expression and the differentiation of bone marrow cells into pericytes
-
1:CAS:528:DC%2BC3MXhsVOhtb7M 3219839 21911740
-
Hamdan R, Zhou Z, Kleinerman ES (2011) SDF-1alpha induces PDGF-B expression and the differentiation of bone marrow cells into pericytes. Mol Cancer Res 9:1462-1470
-
(2011)
Mol Cancer Res
, vol.9
, pp. 1462-1470
-
-
Hamdan, R.1
Zhou, Z.2
Kleinerman, E.S.3
-
133
-
-
84855545329
-
PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells
-
1:CAS:528:DC%2BC3MXhsFGkurbF
-
Xue Y, Lim S, Yang Y, Wang Z, Jensen LD, Hedlund EM, Andersson P, Sasahara M, Larsson O, Galter D, Cao R, Hosaka K, Cao Y (2012) PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells. Nat Med 18:100-110
-
(2012)
Nat Med
, vol.18
, pp. 100-110
-
-
Xue, Y.1
Lim, S.2
Yang, Y.3
Wang, Z.4
Jensen, L.D.5
Hedlund, E.M.6
Andersson, P.7
Sasahara, M.8
Larsson, O.9
Galter, D.10
Cao, R.11
Hosaka, K.12
Cao, Y.13
-
134
-
-
33645890305
-
Regulation of osteoblast differentiation: A novel function for fibroblast growth factor 8
-
1:CAS:528:DC%2BD28XjvFOrtbg%3D 16439448
-
Valta MP, Hentunen T, Qu Q, Valve EM, Harjula A, Seppanen JA, Vaananen HK, Harkonen PL (2006) Regulation of osteoblast differentiation: a novel function for fibroblast growth factor 8. Endocrinology 147:2171-2182
-
(2006)
Endocrinology
, vol.147
, pp. 2171-2182
-
-
Valta, M.P.1
Hentunen, T.2
Qu, Q.3
Valve, E.M.4
Harjula, A.5
Seppanen, J.A.6
Vaananen, H.K.7
Harkonen, P.L.8
-
135
-
-
28244481510
-
Vascular endothelial growth factor contributes to prostate cancer-mediated osteoblastic activity
-
1:CAS:528:DC%2BD2MXht1KjsrzM 16322239
-
Kitagawa Y, Dai J, Zhang J, Keller JM, Nor J, Yao Z, Keller ET (2005) Vascular endothelial growth factor contributes to prostate cancer-mediated osteoblastic activity. Cancer Res 65:10921-10929
-
(2005)
Cancer Res
, vol.65
, pp. 10921-10929
-
-
Kitagawa, Y.1
Dai, J.2
Zhang, J.3
Keller, J.M.4
Nor, J.5
Yao, Z.6
Keller, E.T.7
-
136
-
-
77954563614
-
Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity
-
2865635 20405169
-
DeNardo DG, Andreu P, Coussens LM (2010) Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity. Cancer Metastasis Rev 29:309-316
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 309-316
-
-
Denardo, D.G.1
Andreu, P.2
Coussens, L.M.3
-
137
-
-
78149322663
-
A novel role of IL-17-producing lymphocytes in mediating lytic bone disease in multiple myeloma
-
1:CAS:528:DC%2BC3cXhsVKksb7E 20664052
-
Noonan K, Marchionni L, Anderson J, Pardoll D, Roodman GD, Borrello I (2010) A novel role of IL-17-producing lymphocytes in mediating lytic bone disease in multiple myeloma. Blood 116:3554-3563
-
(2010)
Blood
, vol.116
, pp. 3554-3563
-
-
Noonan, K.1
Marchionni, L.2
Anderson, J.3
Pardoll, D.4
Roodman, G.D.5
Borrello, I.6
-
138
-
-
84871718282
-
Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer
-
3376984 22720236
-
Zhao E, Wang L, Dai J, Kryczek I, Wei S, Vatan L, Altuwaijri S, Sparwasser T, Wang G, Keller ET, Zou W (2012) Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer. Oncoimmunology 1:152-161
-
(2012)
Oncoimmunology
, vol.1
, pp. 152-161
-
-
Zhao, E.1
Wang, L.2
Dai, J.3
Kryczek, I.4
Wei, S.5
Vatan, L.6
Altuwaijri, S.7
Sparwasser, T.8
Wang, G.9
Keller, E.T.10
Zou, W.11
-
139
-
-
84867911410
-
Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells
-
1:CAS:528:DC%2BC38XhsFersLbJ 3531993 23018462
-
Sawant A, Hensel JA, Chanda D, Harris BA, Siegal GP, Maheshwari A, Ponnazhagan S (2012) Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells. J Immunol 189:4258-4265
-
(2012)
J Immunol
, vol.189
, pp. 4258-4265
-
-
Sawant, A.1
Hensel, J.A.2
Chanda, D.3
Harris, B.A.4
Siegal, G.P.5
Maheshwari, A.6
Ponnazhagan, S.7
-
140
-
-
84878069933
-
Multiplex B cell characterization in blood, lymph nodes, and tumors from patients with malignancies
-
1:CAS:528:DC%2BC3sXnvVWru7g%3D 23630345
-
Zirakzadeh AA, Marits P, Sherif A, Winqvist O (2013) Multiplex B cell characterization in blood, lymph nodes, and tumors from patients with malignancies. J Immunol 190:5847-5855
-
(2013)
J Immunol
, vol.190
, pp. 5847-5855
-
-
Zirakzadeh, A.A.1
Marits, P.2
Sherif, A.3
Winqvist, O.4
-
141
-
-
27144471717
-
Increased rejection of primary tumors in mice lacking B cells: Inhibition of anti-tumor CTL and TH1 cytokine responses by B cells
-
1:CAS:528:DC%2BD2MXhtFKjs7rE 15912532
-
Shah S, Divekar AA, Hilchey SP, Cho HM, Newman CL, Shin SU, Nechustan H, Challita-Eid PM, Segal BM, Yi KH, Rosenblatt JD (2005) Increased rejection of primary tumors in mice lacking B cells: inhibition of anti-tumor CTL and TH1 cytokine responses by B cells. Int J Cancer 117:574-586
-
(2005)
Int J Cancer
, vol.117
, pp. 574-586
-
-
Shah, S.1
Divekar, A.A.2
Hilchey, S.P.3
Cho, H.M.4
Newman, C.L.5
Shin, S.U.6
Nechustan, H.7
Challita-Eid, P.M.8
Segal, B.M.9
Yi, K.H.10
Rosenblatt, J.D.11
-
142
-
-
0032400933
-
OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40
-
1:CAS:528:DyaK1cXnslCrt7w%3D 9834095
-
Yun TJ, Chaudhary PM, Shu GL, Frazer JK, Ewings MK, Schwartz SM, Pascual V, Hood LE, Clark EA (1998) OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40. J Immunol 161:6113-6121
-
(1998)
J Immunol
, vol.161
, pp. 6113-6121
-
-
Yun, T.J.1
Chaudhary, P.M.2
Shu, G.L.3
Frazer, J.K.4
Ewings, M.K.5
Schwartz, S.M.6
Pascual, V.7
Hood, L.E.8
Clark, E.A.9
-
143
-
-
78649586268
-
The biology of myeloid-derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity
-
1:CAS:528:DC%2BC3cXhtl2isbfK 3277452 21061430
-
Youn JI, Gabrilovich DI (2010) The biology of myeloid-derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity. Eur J Immunol 40:2969-2975
-
(2010)
Eur J Immunol
, vol.40
, pp. 2969-2975
-
-
Youn, J.I.1
Gabrilovich, D.I.2
-
144
-
-
84881401714
-
Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction
-
3525604 23264895
-
Danilin S, Merkel AR, Johnson JR, Johnson RW, Edwards JR, Sterling JA (2012) Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction. Oncoimmunology 1:1484-1494
-
(2012)
Oncoimmunology
, vol.1
, pp. 1484-1494
-
-
Danilin, S.1
Merkel, A.R.2
Johnson, J.R.3
Johnson, R.W.4
Edwards, J.R.5
Sterling, J.A.6
-
145
-
-
84869222349
-
Osteoclasts in multiple myeloma are derived from Gr-1+CD11b+myeloid- derived suppressor cells
-
1:CAS:528:DC%2BC38XhvVShs7fN 3500251 23173040
-
Zhuang J, Zhang J, Lwin ST, Edwards JR, Edwards CM, Mundy GR, Yang X (2012) Osteoclasts in multiple myeloma are derived from Gr-1+CD11b+myeloid- derived suppressor cells. PloS One 7:e48871
-
(2012)
PloS One
, vol.7
, pp. 48871
-
-
Zhuang, J.1
Zhang, J.2
Lwin, S.T.3
Edwards, J.R.4
Edwards, C.M.5
Mundy, G.R.6
Yang, X.7
|