A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses

PLoS ONE

Volumn 5, Issue 5, 2010, Pages

  Härmä, Ville ^a   Virtanen, Johannes ^b   Mäkelä, Rami ^a   Happonen, Antti ^a   Mpindi, John Patrick ^b   Knuuttila, Matias ^b   Kohonen, Pekka ^b   Lötjönen, Jyrki ^a   Kallioniemi, Olli ^c   Nees, Matthias ^a  

^a VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN; INTERFERON; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; STAT PROTEIN; ANTINEOPLASTIC AGENT; COLLAGEN; LAMININ; MAMMALIAN TARGET OF RAPAMYCIN; MATRIGEL; MESSENGER RNA; PROTEIN SERINE THREONINE KINASE; PROTEOGLYCAN; SIGNAL PEPTIDE; TUMOR PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BASEMENT MEMBRANE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CANCER INVASION; CELL ACTIVATION; CELL CONTACT; CELL DIFFERENTIATION; CELL MATURATION; CELL METABOLISM; CELL SHAPE; CELL TRANSFORMATION; CELL TYPE; CONTROLLED STUDY; DRUG RESPONSE; DRUG TARGETING; EPIGENETICS; EXTRACELLULAR MATRIX; GENE EXPRESSION PROFILING; LIPID METABOLISM; MOLECULAR MODEL; MONOLAYER CULTURE; PROSTATE CANCER; PROSTATE EPITHELIUM; SIGNAL TRANSDUCTION; STEROID METABOLISM; BIOLOGICAL MODEL; CELL PROLIFERATION; DRUG ANTAGONISM; DRUG COMBINATION; DRUG EFFECT; ENZYMOLOGY; EPITHELIUM; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; MESODERM; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; PROSTATE; PROSTATE TUMOR; TUMOR CELL CULTURE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CELL SHAPE; CELL TRANSFORMATION, NEOPLASTIC; COLLAGEN; DRUG COMBINATIONS; EPITHELIAL CELLS; EPITHELIUM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LAMININ; MALE; MESODERM; MODELS, BIOLOGICAL; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; PROSTATE; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED;

EID: 77956287380     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010431     Document Type: Article

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