-
1
-
-
77955273537
-
-
IARC Cancerbase No,10 [Internet] Lyon, France: International Agency for Research on Cancer; 2010
-
Ferlay J SH, Bray F, Forman D, Mathers C, Parkin DM. GLOBOCAN 2008 v1.2, Cancer Incidence and Mortality Worldwide. IARC Cancerbase No,10 [Internet] Lyon, France: International Agency for Research on Cancer; 2010. Available from: http://globocan.iarc.fr. 2010.
-
(2010)
GLOBOCAN 2008 v1.2, Cancer Incidence and Mortality Worldwide
-
-
Ferlay, J.S.H.1
Bray, F.2
Forman, D.3
Mathers, C.4
Parkin, D.M.5
-
2
-
-
68349155807
-
Ovarian carcinoma pathology and genetics: Recent advances
-
Gilks CB, Prat J. Ovarian carcinoma pathology and genetics: recent advances. Human Pathol 2009;40: 1213-23.
-
(2009)
Human Pathol
, vol.40
, pp. 1213-1223
-
-
Gilks, C.B.1
Prat, J.2
-
3
-
-
79959328816
-
Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer-shifting the paradigm
-
Kurman RJ, Shih Ie M. Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer-shifting the paradigm. Human Pathol 2011;42: 918-31.
-
(2011)
Human Pathol
, vol.42
, pp. 918-931
-
-
Kurman, R.J.1
Shih Ie, M.2
-
4
-
-
80053246700
-
The role of targeted therapy in ovarian cancer
-
Banerjee S, Kaye S. The role of targeted therapy in ovarian cancer. Eur J Cancer 2011;47 Suppl 3:S116-30.
-
(2011)
Eur J Cancer
, vol.47
, Issue.SUPPL. 3
-
-
Banerjee, S.1
Kaye, S.2
-
5
-
-
84855425106
-
Incorporation of bevacizumab in the primary treatment of ovarian cancer
-
Burger RA, Brady MF, Bookman MA, Fleming GF, Monk BJ, Huang H, et al. Incorporation of bevacizumab in the primary treatment of ovarian cancer. N Engl J Med 2011;365: 2473-83.
-
(2011)
N Engl J Med
, vol.365
, pp. 2473-2483
-
-
Burger, R.A.1
Brady, M.F.2
Bookman, M.A.3
Fleming, G.F.4
Monk, B.J.5
Huang, H.6
-
6
-
-
84855466019
-
A phase 3 trial of bevacizumab in ovarian cancer
-
Perren TJ, Swart AM, Pfisterer J, Ledermann JA, Pujade-Lauraine E, Kristensen G, et al. A phase 3 trial of bevacizumab in ovarian cancer. N Engl J Med 2011;365: 2484-96.
-
(2011)
N Engl J Med
, vol.365
, pp. 2484-2496
-
-
Perren, T.J.1
Swart, A.M.2
Pfisterer, J.3
Ledermann, J.A.4
Pujade-Lauraine, E.5
Kristensen, G.6
-
7
-
-
84861736119
-
OCEANS: A randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer
-
Aghajanian C, Blank SV, Goff BA, Judson PL, Teneriello MG, Husain A, et al. OCEANS: a randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer. J Clin Oncol 2012;30: 2039-45.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2039-2045
-
-
Aghajanian, C.1
Blank, S.V.2
Goff, B.A.3
Judson, P.L.4
Teneriello, M.G.5
Husain, A.6
-
8
-
-
84866493383
-
AURELIA: A randomized phase III trial evaluating bevacizumab (BEV) plus chemotherapy (CT) for platinum (PT)- resistant recurrent ovarian cancer (OC)
-
abstr LBA5002
-
Pujade-Lauraine E, Hilpert F, Weber B, Reuss A, Andres Poveda, Gunnar Kristensen, et al. AURELIA: a randomized phase III trial evaluating bevacizumab (BEV) plus chemotherapy (CT) for platinum (PT)- resistant recurrent ovarian cancer (OC). J Clin Oncol 2012;30(suppl; abstr LBA5002).
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Pujade-Lauraine, E.1
Hilpert, F.2
Weber, B.3
Reuss, A.4
Poveda, A.5
Kristensen, G.6
-
9
-
-
81255185158
-
Phase 1-2 study of docetaxel plus aflibercept in patients with recurrent ovarian, primary peritoneal, or fallopian tube cancer
-
Coleman RL, Duska LR, Ramirez PT, Heymach JV, Kamat AA, Modesitt SC, et al. Phase 1-2 study of docetaxel plus aflibercept in patients with recurrent ovarian, primary peritoneal, or fallopian tube cancer. Lancet Oncol 2011;12: 1109-17.
-
(2011)
Lancet Oncol
, vol.12
, pp. 1109-1117
-
-
Coleman, R.L.1
Duska, L.R.2
Ramirez, P.T.3
Heymach, J.V.4
Kamat, A.A.5
Modesitt, S.C.6
-
10
-
-
84867908944
-
New ways of assessing ovarian cancer response: Metabolic imaging and beyond
-
Rockall A, Munari A, Avril N. New ways of assessing ovarian cancer response: metabolic imaging and beyond. Cancer Imaging 2012;12: 310-4.
-
(2012)
Cancer Imaging
, vol.12
, pp. 310-314
-
-
Rockall, A.1
Munari, A.2
Avril, N.3
-
11
-
-
84861322375
-
Advanced ovarian cancer: Multiparametric MR imaging demonstrates response- and metastasis-specific effects
-
Sala E, Kataoka MY, Priest AN, Gill AB, McLean MA, Joubert I, et al. Advanced ovarian cancer: multiparametric MR imaging demonstrates response- and metastasis-specific effects. Radiology 2012;263: 149-59.
-
(2012)
Radiology
, vol.263
, pp. 149-159
-
-
Sala, E.1
Kataoka, M.Y.2
Priest, A.N.3
Gill, A.B.4
McLean, M.A.5
Joubert, I.6
-
12
-
-
84863012011
-
Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer
-
Karlan BY, OzaAM, Richardson GE, Provencher DM, Hansen VL, Buck M, et al. Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer. J Clin Oncol 2012;30: 362-71.
-
(2012)
J Clin Oncol
, vol.30
, pp. 362-371
-
-
Karlan, B.Y.1
Oza, A.M.2
Richardson, G.E.3
Provencher, D.M.4
Hansen, V.L.5
Buck, M.6
-
13
-
-
84886725825
-
Brivanib (b) in advanced ovarian cancer (oc): Subset results of a phase 2 randomized discontinuation trial (rdt)
-
S. Kaye S, Siu LL, Jassem J, Medioni J, Soetekouw Pmmb, Slater S, et al. brivanib (b) in advanced ovarian cancer (oc): subset results of a phase 2 randomized discontinuation trial (rdt). Ann Oncol 2012; 23(suppl 9): 319.
-
(2012)
Ann Oncol
, Issue.23 SUPPL. 9
, pp. 319
-
-
Kaye S, S.1
Siu, L.L.2
Jassem, J.3
Medioni, J.4
Pmmb, S.5
Slater, S.6
-
14
-
-
84863888220
-
Combining antiangiogenics to overcome resistance: Rationale and clinical experience
-
Moreno Garcia V, Basu B, Molife LR, Kaye SB. Combining antiangiogenics to overcome resistance: rationale and clinical experience. Clin Cancer Res 2012;18: 3750-61.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3750-3761
-
-
Moreno Garcia, V.1
Basu, B.2
Molife, L.R.3
Kaye, S.B.4
-
15
-
-
77955541508
-
Regulation of tumor angiogenesis by EZH2
-
Lu C, Han HD, Mangala LS, Ali-Fehmi R, Newton CS, Ozbun L, et al. Regulation of tumor angiogenesis by EZH2. Cancer Cell 2010;18: 185-97.
-
(2010)
Cancer Cell
, vol.18
, pp. 185-197
-
-
Lu, C.1
Han, H.D.2
Mangala, L.S.3
Ali-Fehmi, R.4
Newton, C.S.5
Ozbun, L.6
-
16
-
-
80052816881
-
Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer
-
Hu W, Lu C, Dong HH, Huang J, Shen DY, Stone RL, et al. Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer. Cancer Res 2011;71: 6030-9.
-
(2011)
Cancer Res
, vol.71
, pp. 6030-6039
-
-
Hu, W.1
Lu, C.2
Dong, H.H.3
Huang, J.4
Shen, D.Y.5
Stone, R.L.6
-
17
-
-
84863115303
-
Paraneoplastic thrombocytosis in ovarian cancer
-
Stone RL, Nick AM, McNeish IA, Balkwill F, Han HD, Bottsford-Miller J, et al. Paraneoplastic thrombocytosis in ovarian cancer. N Engl J Med 2012;366: 610-8.
-
(2012)
N Engl J Med
, vol.366
, pp. 610-618
-
-
Stone, R.L.1
Nick, A.M.2
McNeish, I.A.3
Balkwill, F.4
Han, H.D.5
Bottsford-Miller, J.6
-
18
-
-
49249119415
-
A synthetic lethal therapeutic approach: Poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair
-
Ashworth A. A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. J Clin Oncol 2008;26: 3785-90.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3785-3790
-
-
Ashworth, A.1
-
19
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005;434: 917-21.
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
-
20
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly (ADP-ribose) polymerase
-
Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly (ADP-ribose) polymerase. Nature 2005;434: 913-7.
-
(2005)
Nature
, vol.434
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
-
21
-
-
77955039099
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: A proof-of-concept trial
-
Audeh MW, Carmichael J, Penson RT, Friedlander M, Powell B, Bell- McGuinn KM, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet 2010;376: 245-51.
-
(2010)
Lancet
, vol.376
, pp. 245-251
-
-
Audeh, M.W.1
Carmichael, J.2
Penson, R.T.3
Friedlander, M.4
Powell, B.5
Bell- McGuinn, K.M.6
-
22
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
Cancer Genome Atlas Research Network.
-
Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature 2011;474: 609-15.
-
(2011)
Nature
, vol.474
, pp. 609-615
-
-
-
23
-
-
80052389761
-
Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: A phase 2, multicentre, open-label, non-randomised study
-
Gelmon KA, Tischkowitz M, Mackay H, Swenerton K, Robidoux A, Tonkin K, et al. Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study. Lancet Oncol 2011;12: 852-61.
-
(2011)
Lancet Oncol
, vol.12
, pp. 852-861
-
-
Gelmon, K.A.1
Tischkowitz, M.2
MacKay, H.3
Swenerton, K.4
Robidoux, A.5
Tonkin, K.6
-
24
-
-
84859523588
-
Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer
-
Ledermann J, Harter P, Gourley C, Friedlander M, Vergote I, Rustin G, et al. Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer. N Engl J Med 2012;366: 1382-92.
-
(2012)
N Engl J Med
, vol.366
, pp. 1382-1392
-
-
Ledermann, J.1
Harter, P.2
Gourley, C.3
Friedlander, M.4
Vergote, I.5
Rustin, G.6
-
25
-
-
84870481616
-
Use of chemotherapy (CT) in BRCA1/2-deficient ovarian cancer (BDOC) patients (pts) with poly-ADP-ribose polymerase inhibitor (PARPi) resistance: A multi-institutional study
-
abstr 5022)
-
Ang JE, Gourley C, High HA, Shapira-Frommer R, Powell CB, Castonguay V, et al. Use of chemotherapy (CT) in BRCA1/2-deficient ovarian cancer (BDOC) patients (pts) with poly-ADP-ribose polymerase inhibitor (PARPi) resistance: a multi-institutional study. J Clin Oncol 2012;30(suppl; abstr 5022).
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Ang, J.E.1
Gourley, C.2
High, H.A.3
Shapira-Frommer, R.4
Powell, C.B.5
Castonguay, V.6
-
27
-
-
84863010984
-
Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer
-
Kaye SB, Lubinski J, Matulonis U, Ang JE, Gourley C, Karlan BY, et al. Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer. J Clin Oncol 2012;30: 372-9.
-
(2012)
J Clin Oncol
, vol.30
, pp. 372-379
-
-
Kaye, S.B.1
Lubinski, J.2
Matulonis, U.3
Ang, J.E.4
Gourley, C.5
Karlan, B.Y.6
-
28
-
-
84866768008
-
Olaparib plus paclitaxel plus carboplatin (P/C) followed by olaparib maintenance treatment in patients (pts) with platinum-sensitive recurrent serous ovarian cancer (PSR SOC): A randomized, openlabel phase II study
-
abstr 5001)
-
Oza AM, Cibula D, Oaknin A, Poole CJ, Mathijssen RHJ, Sonke GS, et al. Olaparib plus paclitaxel plus carboplatin (P/C) followed by olaparib maintenance treatment in patients (pts) with platinum-sensitive recurrent serous ovarian cancer (PSR SOC): a randomized, openlabel phase II study. J Clin Oncol 2012;30(suppl; abstr 5001).
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Oza, A.M.1
Cibula, D.2
Oaknin, A.3
Poole, C.J.4
Mathijssen, R.H.J.5
Sonke, G.S.6
-
29
-
-
84866681744
-
PI3K inhibition impairs BRCA1/2 expression and sensitizesBRCA proficient triple negative breast cancer to PARP inhibition
-
Ibrahim YH, Garcia-Garcia C, Serra V, He L, Torres-Lockhart K, Prat A, et al. PI3K inhibition impairs BRCA1/2 expression and sensitizesBRCA proficient triple negative breast cancer to PARP inhibition. Cancer Discov 2012;2: 1036-47.
-
(2012)
Cancer Discov
, vol.2
, pp. 1036-1047
-
-
Ibrahim, Y.H.1
Garcia-Garcia, C.2
Serra, V.3
He, L.4
Torres-Lockhart, K.5
Prat, A.6
-
30
-
-
84866709651
-
Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for a mouse model of BRCA1-related breast cancer
-
Juvekar A, Burga LN, Hu H, Lunsford EP, Ibrahim YH, Balmana J, et al. Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for a mouse model of BRCA1-related breast cancer. Cancer Discov 2012;2: 1048-63.
-
(2012)
Cancer Discov
, vol.2
, pp. 1048-1063
-
-
Juvekar, A.1
Burga, L.N.2
Hu, H.3
Lunsford, E.P.4
Ibrahim, Y.H.5
Balmana, J.6
-
31
-
-
42249107850
-
PARP-1 inhibition prevents oxidative and nitrosative stress-induced endothelial cell death via transactivation of the VEGF receptor 2
-
Mathews MT, Berk BC. PARP-1 inhibition prevents oxidative and nitrosative stress-induced endothelial cell death via transactivation of the VEGF receptor 2. Arterioscler Thromb Vasc Biol 2008;28: 711-7.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 711-717
-
-
Mathews, M.T.1
Berk, B.C.2
-
32
-
-
76649094290
-
Inhibition of poly(ADP-ribose) polymerase down-regulatesBRCA1 and RAD51 in a pathway mediated by E2F4 and p130
-
Hegan DC, Lu Y, Stachelek GC, Crosby ME, Bindra RS, Glazer PM. Inhibition of poly(ADP-ribose) polymerase down-regulatesBRCA1 and RAD51 in a pathway mediated by E2F4 and p130. Proc Natl Acad Sci U S A 2010;107: 2201-6.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2201-2206
-
-
Hegan, D.C.1
Lu, Y.2
Stachelek, G.C.3
Crosby, M.E.4
Bindra, R.S.5
Glazer, P.M.6
-
33
-
-
84862884719
-
Ovarian low-grade serous carcinoma: A comprehensive update
-
Diaz-Padilla I, Malpica AL, Minig L, Chiva LM, Gershenson DM, Gonzalez-Martin A. Ovarian low-grade serous carcinoma: a comprehensive update. Gynecol Oncol 2012;126: 279-85.
-
(2012)
Gynecol Oncol
, vol.126
, pp. 279-285
-
-
Diaz-Padilla, I.1
Malpica, A.L.2
Minig, L.3
Chiva, L.M.4
Gershenson, D.M.5
Gonzalez-Martin, A.6
-
34
-
-
0037454224
-
Mutations in BRAF and KRAS characterize the development of lowgrade ovarian serous carcinoma
-
Singer G, Oldt R III, Cohen Y, Wang BG, Sidransky D, Kurman RJ, et al. Mutations in BRAF and KRAS characterize the development of lowgrade ovarian serous carcinoma. J Natl Cancer Inst 2003;95: 484-6.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 484-486
-
-
Singer, G.1
Oldt Iii, R.2
Cohen, Y.3
Wang, B.G.4
Sidransky, D.5
Kurman, R.J.6
-
35
-
-
77957354624
-
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas
-
Wong KK, Tsang YT, Deavers MT, Mok SC, Zu Z, Sun C, et al. BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas. Am J Pathol 2010;177: 1611-7.
-
(2010)
Am J Pathol
, vol.177
, pp. 1611-1617
-
-
Wong, K.K.1
Tsang, Y.T.2
Deavers, M.T.3
Mok, S.C.4
Zu, Z.5
Sun, C.6
-
36
-
-
84873079682
-
Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: An open-label, single-arm, phase 2 study
-
Farley J, Brady WE, Vathipadiekal V, Lankes HA, Coleman R, Morgan MA, et al. Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study. Lancet Oncol 2013;14: 134-40.
-
(2013)
Lancet Oncol
, vol.14
, pp. 134-140
-
-
Farley, J.1
Brady, W.E.2
Vathipadiekal, V.3
Lankes, H.A.4
Coleman, R.5
Morgan, M.A.6
-
37
-
-
84863794715
-
The association of PI3 kinase signaling and chemoresistance in advanced ovarian cancer
-
Carden CP, Stewart A, Thavasu P, Kipps E, Pope L, Crespo M, et al. The association of PI3 kinase signaling and chemoresistance in advanced ovarian cancer. Mol Cancer Ther 2012;11: 1609-17.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 1609-1617
-
-
Carden, C.P.1
Stewart, A.2
Thavasu, P.3
Kipps, E.4
Pope, L.5
Crespo, M.6
-
38
-
-
77955649600
-
Targeting the epidermal growth factor receptor in epithelial ovarian cancer: Current knowledge and future challenges
-
Siwak DR, Carey M, Hennessy BT, Nguyen CT, McGahren Murray MJ, Nolden L, et al. Targeting the epidermal growth factor receptor in epithelial ovarian cancer: current knowledge and future challenges. J Oncol 2010;2010: 568938.
-
(2010)
J Oncol
, vol.2010
, pp. 568938
-
-
Siwak, D.R.1
Carey, M.2
Hennessy, B.T.3
Nguyen, C.T.4
McGahren Murray, M.J.5
Nolden, L.6
-
39
-
-
23044511620
-
Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: A Gynecologic Oncology Group Study
-
Schilder RJ, Sill MW, Chen X, Darcy KM, Decesare SL, Lewandowski G, et al. Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: a Gynecologic Oncology Group Study. Clin Cancer Res 2005; 11: 5539-48.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5539-5548
-
-
Schilder, R.J.1
Sill, M.W.2
Chen, X.3
Darcy, K.M.4
Decesare, S.L.5
Lewandowski, G.6
-
40
-
-
84867062943
-
Randomized phase III study of erlotinib versus observation in patients with no evidence of disease progression after first-line platin-based chemotherapy for ovarian carcinoma:AGCIG andEORTC-GCGstudy
-
abstr LBA5000)
-
Vergote IB, Joly F, Katsaros D, Coens C, Reinthaller A, Hall M, et al. Randomized phase III study of erlotinib versus observation in patients with no evidence of disease progression after first-line platin-based chemotherapy for ovarian carcinoma:AGCIG andEORTC-GCGstudy. J Clin Oncol 2012;30(suppl; abstr LBA5000).
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Vergote, I.B.1
Joly, F.2
Katsaros, D.3
Coens, C.4
Reinthaller, A.5
Hall, M.6
-
41
-
-
0037440042
-
Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: A phase II trial of the Gynecologic Oncology Group
-
Bookman MA, Darcy KM, Clarke-Pearson D, Boothby RA, Horowitz IR. Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology Group. J Clin Oncol 2003;21: 283-90.
-
(2003)
J Clin Oncol
, vol.21
, pp. 283-290
-
-
Bookman, M.A.1
Darcy, K.M.2
Clarke-Pearson, D.3
Boothby, R.A.4
Horowitz, I.R.5
-
42
-
-
33749003463
-
Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: Potential predictive relationship with tumor HER2 activation status
-
Gordon MS, Matei D, Aghajanian C, Matulonis UA, Brewer M, Fleming GF, et al. Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status. J Clin Oncol 2006;24: 4324-32.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4324-4332
-
-
Gordon, M.S.1
Matei, D.2
Aghajanian, C.3
Matulonis, U.A.4
Brewer, M.5
Fleming, G.F.6
-
43
-
-
84879188868
-
A randomized phase II study evaluating the combination of carboplatin-based chemotherapy with pertuzumab versus carboplatin-based therapy alone in patients with relapsed, platinum-sensitive ovarian cancer
-
Kaye SB, Poole CJ, Danska-Bidzinska A, Gianni L, Del Conte G, Gorbunova V, et al. A randomized phase II study evaluating the combination of carboplatin-based chemotherapy with pertuzumab versus carboplatin-based therapy alone in patients with relapsed, platinum-sensitive ovarian cancer. Ann Oncol 2013;24: 145-52.
-
(2013)
Ann Oncol
, vol.24
, pp. 145-152
-
-
Kaye, S.B.1
Poole, C.J.2
Danska-Bidzinska, A.3
Gianni, L.4
Del Conte, G.5
Gorbunova, V.6
-
44
-
-
84872862768
-
Molecular characterization of mucinous ovarian tumors supports a stratified treatment approach with HER2 targeting in 18% of carcinomas
-
Anglesio M, Kommoss S, Tolcher M, Clarke B, Galletta L, Porter H, et al. Molecular characterization of mucinous ovarian tumors supports a stratified treatment approach with HER2 targeting in 18% of carcinomas. J Pathol 2013;229: 111-20.
-
(2013)
J Pathol
, vol.229
, pp. 111-120
-
-
Anglesio, M.1
Kommoss, S.2
Tolcher, M.3
Clarke, B.4
Galletta, L.5
Porter, H.6
-
45
-
-
33749034462
-
ErbB-3 predicts survival in ovarian cancer
-
Tanner B, Hasenclever D, Stern K, Schormann W, Bezler M, Hermes M, et al. ErbB-3 predicts survival in ovarian cancer. J Clin Oncol 2006; 24: 4317-23.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4317-4323
-
-
Tanner, B.1
Hasenclever, D.2
Stern, K.3
Schormann, W.4
Bezler, M.5
Hermes, M.6
-
46
-
-
77954958218
-
Elevated expression of erbB3 confers paclitaxel resistance in erbB2-overexpressing breast cancer cells via upregulation of Survivin
-
Wang S, Huang X, Lee CK, Liu B. Elevated expression of erbB3 confers paclitaxel resistance in erbB2-overexpressing breast cancer cells via upregulation of Survivin. Oncogene 2010;29: 4225-36.
-
(2010)
Oncogene
, vol.29
, pp. 4225-4236
-
-
Wang, S.1
Huang, X.2
Lee, C.K.3
Liu, B.4
-
47
-
-
77649314140
-
An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells
-
Sheng Q, Liu X, Fleming E, Yuan K, Piao H, Chen J, et al. An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells. Cancer Cell 2010;17: 298-310.
-
(2010)
Cancer Cell
, vol.17
, pp. 298-310
-
-
Sheng, Q.1
Liu, X.2
Fleming, E.3
Yuan, K.4
Piao, H.5
Chen, J.6
-
48
-
-
84865676963
-
Phase II evaluation of dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: A Gynecologic Oncology Group study
-
Schilder RJ, Brady WE, Lankes HA, Fiorica JV, Shahin MS, Zhou XC, et al. Phase II evaluation of dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group study. Gynecol Oncol 2012;127: 70-4.
-
(2012)
Gynecol Oncol
, vol.127
, pp. 70-74
-
-
Schilder, R.J.1
Brady, W.E.2
Lankes, H.A.3
Fiorica, J.V.4
Shahin, M.S.5
Zhou, X.C.6
-
49
-
-
84874855457
-
A randomized phase II clinical trial of the src inhibitor saracatinib (AZD0530) and carboplatin 1 paclitaxel (C1P) versus C1P in patients (pts) with advanced platinum-sensitive epithelial ovarian cancer (EOC) [abstract]
-
Oct 8-12; Milan, Italy. 2010; Abstract nr 9720.
-
Poole C, Lisyanskaya A, Rodenhuis S, Kristensen G, Pujade Lauraine E, Cantarin M, et al. A randomized phase II clinical trial of the Src inhibitor saracatinib (AZD0530) and carboplatin 1 paclitaxel (C1P) versus C1P in patients (pts) with advanced platinum-sensitive epithelial ovarian cancer (EOC) [abstract]. In: Proceedings of the 35th ESMO Congress; Oct 8-12 2010; Milan, Italy. 2010;21 (Suppl 8) Abstract nr 9720.
-
(2010)
Proceedings of the 35th ESMO Congress
, vol.21
, Issue.SUPPL. 8
-
-
Poole, C.1
Lisyanskaya, A.2
Rodenhuis, S.3
Kristensen, G.4
Pujade Lauraine, E.5
Cantarin, M.6
-
50
-
-
28544449918
-
SRC tyrosine kinase and multidrug resistance protein-1 inhibitions act independently but cooperatively to restore paclitaxel sensitivity to paclitaxel-resistant ovarian cancer cells
-
George JA, Chen T, Taylor CC. SRC tyrosine kinase and multidrug resistance protein-1 inhibitions act independently but cooperatively to restore paclitaxel sensitivity to paclitaxel-resistant ovarian cancer cells. Cancer Res 2005;65: 10381-8.
-
(2005)
Cancer Res
, vol.65
, pp. 10381-10388
-
-
George, J.A.1
Chen, T.2
Taylor, C.C.3
-
51
-
-
77953088280
-
Insulin-like growth factor 2 expression modulates Taxol resistance and is a candidate biomarker for reduced disease-free survival in ovarian cancer
-
Huang GS, Brouwer-Visser J, Ramirez MJ, Kim CH, Hebert TM, Lin J, et al. Insulin-like growth factor 2 expression modulates Taxol resistance and is a candidate biomarker for reduced disease-free survival in ovarian cancer. Clin Cancer Res 2010;16: 2999-3010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2999-3010
-
-
Huang, G.S.1
Brouwer-Visser, J.2
Ramirez, M.J.3
Kim, C.H.4
Hebert, T.M.5
Lin, J.6
-
52
-
-
80052583874
-
The insulin-like growth factor 1 pathway is a potential therapeutic target for low-grade serous ovarian carcinoma
-
King ER, Zu Z, Tsang YT, DeaversMT,Malpica A, Mok SC, et al. The insulin-like growth factor 1 pathway is a potential therapeutic target for low-grade serous ovarian carcinoma. Gynecol Oncol 2011;123: 13-8.
-
(2011)
Gynecol Oncol
, vol.123
, pp. 13-18
-
-
King, E.R.1
Zu, Z.2
Tsang, Y.T.3
Deaversmtmalpica, A.4
Mok, S.C.5
-
53
-
-
70949083026
-
Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents
-
Hirai H, Iwasawa Y, Okada M, Arai T, Nishibata T, Kobayashi M, et al. Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents. Mol Cancer Ther 2009;8: 2992-3000.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2992-3000
-
-
Hirai, H.1
Iwasawa, Y.2
Okada, M.3
Arai, T.4
Nishibata, T.5
Kobayashi, M.6
-
54
-
-
79956224870
-
A phase i pharmacological and pharmacodynamic study of MK-1775, a Wee1 tyrosine kinase inhibitor, in monotherapy and combination with gemcitabine, cisplatin, or carboplatin in patients with advanced solid tumors
-
(May 20 supplement; abstr 3067)
-
Leijen S, Schellens JH, Shapiro G, Pavlick AC, Tibes R, Demuth T, et al. A phase I pharmacological and pharmacodynamic study of MK-1775, a Wee1 tyrosine kinase inhibitor, in monotherapy and combination with gemcitabine, cisplatin, or carboplatin in patients with advanced solid tumors. J Clin Oncol 2010;28(May 20 supplement; abstr 3067).
-
(2010)
J Clin Oncol
, vol.28
-
-
Leijen, S.1
Schellens, J.H.2
Shapiro, G.3
Pavlick, A.C.4
Tibes, R.5
Demuth, T.6
-
55
-
-
84865681647
-
Phase II study of MLN8237 (alisertib), an investigational Aurora A kinase inhibitor, in patients with platinum-resistant or -refractory epithelial ovarian, fallopian tube, or primary peritoneal carcinoma
-
Matulonis UA, Sharma S, Ghamande S, Gordon MS, Del Prete SA, Ray-Coquard I, et al. Phase II study of MLN8237 (alisertib), an investigational Aurora A kinase inhibitor, in patients with platinum-resistant or -refractory epithelial ovarian, fallopian tube, or primary peritoneal carcinoma. Gynecol Oncol 2012;127: 63-9.
-
(2012)
Gynecol Oncol
, vol.127
, pp. 63-69
-
-
Matulonis, U.A.1
Sharma, S.2
Ghamande, S.3
Gordon, M.S.4
Del Prete, S.A.5
Ray-Coquard, I.6
-
56
-
-
77955887094
-
PRECEDENT: A randomized phase II trial comparing EC145 and pegylated liposomal doxorubicin (PLD) in combination, versus PLD alone, in subjects with platinum-resistant ovarian cancer
-
(suppl; abstr LBA5012b)
-
Naumann RW, Symanowski JT, Ghamande SA, Gabrail NY, Gilbert L, Teneriello MG, et al. PRECEDENT: a randomized phase II trial comparing EC145 and pegylated liposomal doxorubicin (PLD) in combination, versus PLD alone, in subjects with platinum-resistant ovarian cancer. J Clin Oncol 2010;28: 18s (suppl; abstr LBA5012b).
-
(2010)
J Clin Oncol
, vol.28
, pp. 18
-
-
Naumann, R.W.1
Symanowski, J.T.2
Ghamande, S.A.3
Gabrail, N.Y.4
Gilbert, L.5
Teneriello, M.G.6
-
57
-
-
79951825513
-
Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2
-
Rizzo S, Hersey JM, Mellor P, Dai W, Santos-Silva A, Liber D, et al. Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2. Mol Cancer Ther 2011;10: 325-35.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 325-335
-
-
Rizzo, S.1
Hersey, J.M.2
Mellor, P.3
Dai, W.4
Santos-Silva, A.5
Liber, D.6
-
58
-
-
77957946398
-
ARID1A mutations in endometriosis-associated ovarian carcinomas
-
Wiegand KC, Shah SP, Al-Agha OM, Zhao Y, Tse K, Zeng T, et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med 2010;363: 1532-43.
-
(2010)
N Engl J Med
, vol.363
, pp. 1532-1543
-
-
Wiegand, K.C.1
Shah, S.P.2
Al-Agha, O.M.3
Zhao, Y.4
Tse, K.5
Zeng, T.6
-
59
-
-
84862908497
-
Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers
-
Heravi-Moussavi A, Anglesio MS, Cheng SW, Senz J, Yang W, Prentice L, et al. Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers. N Engl J Med 2012;366: 234-42.
-
(2012)
N Engl J Med
, vol.366
, pp. 234-242
-
-
Heravi-Moussavi, A.1
Anglesio, M.S.2
Cheng, S.W.3
Senz, J.4
Yang, W.5
Prentice, L.6
-
60
-
-
79952568603
-
Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas
-
McConechy MK, Anglesio MS, Kalloger SE, Yang W, Senz J, Chow C, et al. Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas. J Pathol 2011;223: 567-73.
-
(2011)
J Pathol
, vol.223
, pp. 567-573
-
-
McConechy, M.K.1
Anglesio, M.S.2
Kalloger, S.E.3
Yang, W.4
Senz, J.5
Chow, C.6
-
61
-
-
79953168439
-
FOXL2 is a sensitive and specific marker for sex cord-stromal tumors of the ovary
-
Al-Agha OM, Huwait HF, Chow C, Yang W, Senz J, Kalloger SE, et al. FOXL2 is a sensitive and specific marker for sex cord-stromal tumors of the ovary. Am J Surg Pathol 2011;35: 484-94.
-
(2011)
Am J Surg Pathol
, vol.35
, pp. 484-494
-
-
Al-Agha, O.M.1
Huwait, H.F.2
Chow, C.3
Yang, W.4
Senz, J.5
Kalloger, S.E.6
-
62
-
-
84861860715
-
The changing view of high-grade serous ovarian cancer
-
Berns EM, Bowtell DD. The changing view of high-grade serous ovarian cancer. Cancer Res 2012;72: 2701-4.
-
(2012)
Cancer Res
, vol.72
, pp. 2701-2704
-
-
Berns, E.M.1
Bowtell, D.D.2
-
63
-
-
84867398634
-
Prevalence of loss of expression of DNA mismatch repair proteins in primary epithelial ovarian tumors
-
Lu FI, Gilks CB, Mulligan AM, Ryan P, Allo G, Sy K, et al. Prevalence of Loss of Expression of DNA Mismatch Repair Proteins in Primary Epithelial Ovarian Tumors. Int J Gynecol Pathol 2012;31: 524-31.
-
(2012)
Int J Gynecol Pathol
, vol.31
, pp. 524-531
-
-
Lu, F.I.1
Gilks, C.B.2
Mulligan, A.M.3
Ryan, P.4
Allo, G.5
Sy, K.6
-
64
-
-
10044266232
-
Molecular genetic alterations in endometrioid carcinomas of the ovary: Similar frequency of beta-catenin abnormalities but lower rate of microsatellite instability and PTEN alterations than in uterine endometrioid carcinomas
-
Catasus L, Bussaglia E, Rodrguez I, Gallardo A, Pons C, Irving JA, et al. Molecular genetic alterations in endometrioid carcinomas of the ovary: similar frequency of beta-catenin abnormalities but lower rate of microsatellite instability and PTEN alterations than in uterine endometrioid carcinomas. Human Pathol 2004;35: 1360-8.
-
(2004)
Human Pathol
, vol.35
, pp. 1360-1368
-
-
Catasus, L.1
Bussaglia, E.2
Rodrguez, I.3
Gallardo, A.4
Pons, C.5
Irving, J.A.6
-
65
-
-
69349088990
-
Ovarian low-grade and high-grade serous carcinoma: Pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problems
-
Vang R, Shih Ie M, Kurman RJ. Ovarian low-grade and high-grade serous carcinoma: pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problems. Adv Anat Pathol 2009;16: 267-82.
-
(2009)
Adv Anat Pathol
, vol.16
, pp. 267-282
-
-
Vang, R.1
Shih Ie, M.2
Kurman, R.J.3
|