-
1
-
-
0038481970
-
The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
-
DOI 10.1038/nrc1098
-
Fidler, I. J. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nature Rev. Cancer 3, 453-458 (2003). (Pubitemid 37328849)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.6
, pp. 453-458
-
-
Fidler, I.J.1
-
2
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
0036674501
-
Dissemination and growth of cancer cells in metastatic sites
-
DOI 10.1038/nrc865
-
Chambers, A. F., Groom, A. C. & MacDonald, I. C. Dissemination and growth of cancer cells in metastatic sites. Nature Rev. Cancer 2, 563-572 (2002). (Pubitemid 37328923)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.8
, pp. 563-572
-
-
Chambers, A.F.1
Groom, A.C.2
MacDonald, I.C.3
-
4
-
-
33751252276
-
Cancer Metastasis: Building a Framework
-
DOI 10.1016/j.cell.2006.11.001, PII S0092867406014140
-
Gupta, G. P. & Massague, J. Cancer metastasis: building a framework. Cell 127, 679-695 (2006). (Pubitemid 44781029)
-
(2006)
Cell
, vol.127
, Issue.4
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
5
-
-
63049090100
-
Metastasis: From dissemination to organ-specific colonization
-
Nguyen, D. X., Bos, P. D. & Massague, J. Metastasis: from dissemination to organ-specific colonization. Nature Rev. Cancer 9, 274-284 (2009).
-
(2009)
Nature Rev. Cancer
, vol.9
, pp. 274-284
-
-
Nguyen, D.X.1
Bos, P.D.2
Massague, J.3
-
6
-
-
0024708518
-
The distribution of secondary growths in cancer of the breast 1889
-
Paget, S. The distribution of secondary growths in cancer of the breast. 1889. Cancer Metastasis Rev. 8, 98-101 (1989).
-
(1989)
Cancer Metastasis Rev.
, vol.8
, pp. 98-101
-
-
Paget, S.1
-
7
-
-
79953147370
-
A perspective on cancer cell metastasis
-
Chaffer, C. L. & Weinberg, R. A. A perspective on cancer cell metastasis. Science 331, 1559-1564 (2011).
-
(2011)
Science
, vol.331
, pp. 1559-1564
-
-
Chaffer, C.L.1
Weinberg, R.A.2
-
8
-
-
63049102497
-
Parallel progression of primary tumours and metastases
-
Klein, C. A. Parallel progression of primary tumours and metastases. Nature Rev. Cancer 9, 302-312 (2009).
-
(2009)
Nature Rev. Cancer
, vol.9
, pp. 302-312
-
-
Klein, C.A.1
-
9
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding, L. et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 464, 999-1005 (2010).
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
-
10
-
-
79953766940
-
Tumour evolution inferred by single-cell sequencing
-
Navin, N. et al. Tumour evolution inferred by single-cell sequencing. Nature 472, 90-94 (2011).
-
(2011)
Nature
, vol.472
, pp. 90-94
-
-
Navin, N.1
-
11
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
Joyce, J. A. & Pollard, J. W. Microenvironmental regulation of metastasis. Nature Rev. Cancer 9, 239-252 (2009).
-
(2009)
Nature Rev. Cancer
, vol.9
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
12
-
-
34247269026
-
Genetic determinants of cancer metastasis
-
DOI 10.1038/nrg2101, PII NRG2101
-
Nguyen, D. X. & Massague, J. Genetic determinants of cancer metastasis. Nature Rev. Genet. 8, 341-352 (2007). (Pubitemid 46625811)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.5
, pp. 341-352
-
-
Nguyen, D.X.1
Massague, J.2
-
13
-
-
34948896045
-
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
-
DOI 10.1038/nature06188, PII NATURE06188
-
Karnoub, A. E. et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 449, 557-563 (2007). (Pubitemid 47525152)
-
(2007)
Nature
, vol.449
, Issue.7162
, pp. 557-563
-
-
Karnoub, A.E.1
Dash, A.B.2
Vo, A.P.3
Sullivan, A.4
Brooks, M.W.5
Bell, G.W.6
Richardson, A.L.7
Polyak, K.8
Tubo, R.9
Weinberg, R.A.10
-
14
-
-
9244227134
-
Stromal fibroblasts in cancer initiation and progression
-
DOI 10.1038/nature03096
-
Bhowmick, N. A., Neilson, E. G. & Moses, H. L. Stromal fibroblasts in cancer initiation and progression. Nature 432, 332-337 (2004). (Pubitemid 39551661)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
15
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
-
Orimo, A. et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121, 335-348 (2005). (Pubitemid 40692295)
-
(2005)
Cell
, vol.121
, Issue.3
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.J.7
Richardson, A.L.8
Weinberg, R.A.9
-
16
-
-
79958265710
-
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell States in the breast
-
Scheel, C. et al. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell States in the breast. Cell 145, 926-940 (2011).
-
(2011)
Cell
, vol.145
, pp. 926-940
-
-
Scheel, C.1
-
17
-
-
79957484310
-
Cancer to bone: A fatal attraction
-
Weilbaecher, K. N., Guise, T. A. & McCauley, L. K. Cancer to bone: a fatal attraction. Nature Rev. Cancer 11, 411-425 (2011).
-
(2011)
Nature Rev. Cancer
, vol.11
, pp. 411-425
-
-
Weilbaecher, K.N.1
Guise, T.A.2
McCauley, L.K.3
-
18
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
DOI 10.1016/S1535-6108(03)00132-6
-
Kang, Y. et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3, 537-549 (2003). (Pubitemid 36808649)
-
(2003)
Cancer Cell
, vol.3
, Issue.6
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordon-Cardo, C.6
Guise, T.A.7
Massague, J.8
-
19
-
-
67649300721
-
Genes that mediate breast cancer metastasis to the brain
-
Bos, P. D. et al. Genes that mediate breast cancer metastasis to the brain. Nature 459, 1005-1009 (2009).
-
(2009)
Nature
, vol.459
, pp. 1005-1009
-
-
Bos, P.D.1
-
20
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
DOI 10.1038/nature03799
-
Minn, A. J. et al. Genes that mediate breast cancer metastasis to lung. Nature 436, 518-524 (2005). (Pubitemid 41112921)
-
(2005)
Nature
, vol.436
, Issue.7050
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
Bos, P.D.4
Shu, W.5
Giri, D.D.6
Viale, A.7
Olshen, A.B.8
Gerald, W.L.9
Massague, J.10
-
21
-
-
34648832906
-
Illuminating the metastatic process
-
DOI 10.1038/nrc2229, PII NRC2229
-
Sahai, E. Illuminating the metastatic process. Nature Rev. Cancer 7, 737-749 (2007). (Pubitemid 47463672)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.10
, pp. 737-749
-
-
Sahai, E.1
-
22
-
-
73849129203
-
Real-time imaging reveals the single steps of brain metastasis formation
-
Kienast, Y. et al. Real-time imaging reveals the single steps of brain metastasis formation. Nature Med. 16, 116-122 (2010).
-
(2010)
Nature Med.
, vol.16
, pp. 116-122
-
-
Kienast, Y.1
-
23
-
-
57049128693
-
Intravital imaging of metastatic behavior through a mammary imaging window
-
Kedrin, D. et al. Intravital imaging of metastatic behavior through a mammary imaging window. Nature Methods 5, 1019-1021 (2008).
-
(2008)
Nature Methods
, vol.5
, pp. 1019-1021
-
-
Kedrin, D.1
-
24
-
-
0345059766
-
Intravital imaging of cell movement in tumours
-
Condeelis, J. & Segall, J. E. Intravital imaging of cell movement in tumours. Nature Rev. Cancer 3, 921-930 (2003). (Pubitemid 37500177)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.12
, pp. 921-930
-
-
Condeelis, J.1
Segall, J.E.2
-
25
-
-
0028806048
-
Quantitative monitoring of gene expression patterns with a complementary DNA microarray
-
Schena, M., Shalon, D., Davis, R. W. & Brown, P. O. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270, 467-470 (1995).
-
(1995)
Science
, vol.270
, pp. 467-470
-
-
Schena, M.1
Shalon, D.2
Davis, R.W.3
Brown, P.O.4
-
26
-
-
55549089660
-
Accurate whole human genome sequencing using reversible terminator chemistry
-
Bentley, D. R. et al. Accurate whole human genome sequencing using reversible terminator chemistry. Nature 456, 53-59 (2008).
-
(2008)
Nature
, vol.456
, pp. 53-59
-
-
Bentley, D.R.1
-
27
-
-
33750456519
-
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
-
DOI 10.1016/j.cell.2006.09.026, PII S0092867406012748
-
Olsen, J. V. et al. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127, 635-648 (2006). (Pubitemid 44647421)
-
(2006)
Cell
, vol.127
, Issue.3
, pp. 635-648
-
-
Olsen, J.V.1
Blagoev, B.2
Gnad, F.3
Macek, B.4
Kumar, C.5
Mortensen, P.6
Mann, M.7
-
28
-
-
3242683662
-
Single cell profiling of potentiated phospho-protein networks in cancer cells
-
DOI 10.1016/j.cell.2004.06.028, PII S0092867404006282
-
Irish, J. M. et al. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell 118, 217-228 (2004). (Pubitemid 38962577)
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 217-228
-
-
Irish, J.M.1
Hovland, R.2
Krutzik, P.O.3
Perez, O.D.4
Bruserud, O.5
Gjertsen, B.T.6
Nolan, G.P.7
-
29
-
-
0037708932
-
Metastatic potential: Generic predisposition of the primary tumor or rare, metastatic variants - Or both?
-
DOI 10.1016/S0092-8674(03)00468-9
-
Hynes, R. O. Metastatic potential: generic predisposition of the primary tumor or rare, metastatic variants-or both? Cell 113, 821-823 (2003). (Pubitemid 36792026)
-
(2003)
Cell
, vol.113
, Issue.7
, pp. 821-823
-
-
Hynes, R.O.1
-
30
-
-
38549131901
-
GATA-3 Links Tumor Differentiation and Dissemination in a Luminal Breast Cancer Model
-
DOI 10.1016/j.ccr.2008.01.011, PII S1535610808000081
-
Kouros-Mehr, H. et al. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell 13, 141-152 (2008). (Pubitemid 351163164)
-
(2008)
Cancer Cell
, vol.13
, Issue.2
, pp. 141-152
-
-
Kouros-Mehr, H.1
Bechis, S.K.2
Slorach, E.M.3
Littlepage, L.E.4
Egeblad, M.5
Ewald, A.J.6
Pai, S.-Y.7
Ho, I.-C.8
Werb, Z.9
-
31
-
-
67349257845
-
Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer
-
Liu, W. et al. Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nature Med. 15, 559-565 (2009).
-
(2009)
Nature Med.
, vol.15
, pp. 559-565
-
-
Liu, W.1
-
32
-
-
78049380554
-
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
-
Campbell, P. J. et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature 467, 1109-1113 (2010).
-
(2010)
Nature
, vol.467
, pp. 1109-1113
-
-
Campbell, P.J.1
-
33
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida, S. et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 467, 1114-1117 (2010).
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
-
34
-
-
41949139438
-
Comparative lesion sequencing provides insights into tumor evolution
-
DOI 10.1073/pnas.0712345105
-
Jones, S. et al. Comparative lesion sequencing provides insights into tumor evolution. Proc. Natl Acad. Sci. USA 105, 4283-4288 (2008). (Pubitemid 351754372)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.11
, pp. 4283-4288
-
-
Jones, S.1
Chen, W.-D.2
Parmigiani, G.3
Diehl, F.4
Beerenwinkel, N.5
Antal, T.6
Traulsen, A.7
Nowak, M.A.8
Siegel, C.9
Velculescu, V.E.10
Kinzler, K.W.11
Vogelstein, B.12
Willis, J.13
Markowitz, S.D.14
-
35
-
-
0016692602
-
Mutation selection and the natural history of cancer
-
Cairns, J. Mutation selection and the natural history of cancer. Nature 255, 197-200 (1975).
-
(1975)
Nature
, vol.255
, pp. 197-200
-
-
Cairns, J.1
-
36
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou, C. M. et al. Molecular portraits of human breast tumours. Nature 406, 747-752 (2000).
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
-
37
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
DOI 10.1073/pnas.191367098
-
Sorlie, T. et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl Acad. Sci. USA 98, 10869-10874 (2001). (Pubitemid 32878711)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
Hastie, T.7
Eisen, M.B.8
Van De Rijn, M.9
Jeffrey, S.S.10
Thorsen, T.11
Quist, H.12
Matese, J.C.13
Brown, P.O.14
Botstein, D.15
Lonning, P.E.16
Borresen-Dale, A.-L.17
-
38
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
Van 't Veer, L. J. et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 415, 530-536 (2002).
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
Van 'T Veer, L.J.1
-
39
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
DOI 10.1056/NEJMoa021967
-
Van de Vijver, M. J. et al. A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med. 347, 1999-2009 (2002). (Pubitemid 35461656)
-
(2002)
New England Journal of Medicine
, vol.347
, Issue.25
, pp. 1999-2009
-
-
Van De Vijver, M.J.1
He, Y.D.2
Van 'T Veer, L.J.3
Dai, H.4
Hart, A.A.M.5
Voskuil, D.W.6
Schreiber, G.J.7
Peterse, J.L.8
Roberts, C.9
Marton, M.J.10
Parrish, M.11
Atsma, D.12
Witteveen, A.13
Glas, A.14
Delahaye, L.15
Van Der Velde, T.16
Bartelink, H.17
Rodenhuis, S.18
Rutgers, E.T.19
Friend, S.H.20
Bernards, R.21
more..
-
40
-
-
70349438989
-
A luminal epithelial stem cell that is a cell of origin for prostate cancer
-
Wang, X. et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 461, 495-500 (2009).
-
(2009)
Nature
, vol.461
, pp. 495-500
-
-
Wang, X.1
-
41
-
-
68349130357
-
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
-
Lim, E. et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nature Med. 15, 907-913 (2009).
-
(2009)
Nature Med.
, vol.15
, pp. 907-913
-
-
Lim, E.1
-
42
-
-
77956218241
-
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
-
Molyneux, G. et al. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell 7, 403-417 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 403-417
-
-
Molyneux, G.1
-
43
-
-
34547566701
-
Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes
-
DOI 10.1016/j.ccr.2007.06.013, PII S1535610807001791
-
Ince, T. A. et al. Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes. Cancer Cell 12, 160-170 (2007). (Pubitemid 47199120)
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 160-170
-
-
Ince, T.A.1
Richardson, A.L.2
Bell, G.W.3
Saitoh, M.4
Godar, S.5
Karnoub, A.E.6
Iglehart, J.D.7
Weinberg, R.A.8
-
44
-
-
33846239456
-
Beyond tumorigenesis: Cancer stem cells in metastasis
-
DOI 10.1038/sj.cr.7310118, PII 7310118
-
Li, F., Tiede, B., Massague, J. & Kang, Y. Beyond tumorigenesis: cancer stem cells in metastasis. Cell Res. 17, 3-14 (2007). (Pubitemid 46096419)
-
(2007)
Cell Research
, vol.17
, Issue.1
, pp. 3-14
-
-
Li, F.1
Tiede, B.2
Massague, J.3
Kang, Y.4
-
45
-
-
77955175049
-
Cross-species genomics matches driver mutations and cell compartments to model ependymoma
-
Johnson, R. A. et al. Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature 466, 632-636 (2010).
-
(2010)
Nature
, vol.466
, pp. 632-636
-
-
Johnson, R.A.1
-
46
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
Barker, N. et al. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457, 608-611 (2009).
-
(2009)
Nature
, vol.457
, pp. 608-611
-
-
Barker, N.1
-
47
-
-
77955121375
-
Identification of a cell of origin for human prostate cancer
-
Goldstein, A. S., Huang, J., Guo, C., Garraway, I. P. & Witte, O. N. Identification of a cell of origin for human prostate cancer. Science 329, 568-571 (2010).
-
(2010)
Science
, vol.329
, pp. 568-571
-
-
Goldstein, A.S.1
Huang, J.2
Guo, C.3
Garraway, I.P.4
Witte, O.N.5
-
48
-
-
79958761641
-
Cell of origin of small cell lung cancer: Inactivation of Trp53 and rb1 in distinct cell types of adult mouse lung
-
Sutherland, K. D. et al. Cell of origin of small cell lung cancer: inactivation of Trp53 and rb1 in distinct cell types of adult mouse lung. Cancer Cell 19, 754-764 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 754-764
-
-
Sutherland, K.D.1
-
49
-
-
77649258546
-
Identification of the cell lineage at the origin of basal cell carcinoma
-
Youssef, K. K. et al. Identification of the cell lineage at the origin of basal cell carcinoma. Nature Cell Biol. 12, 299-305 (2010).
-
(2010)
Nature Cell Biol.
, vol.12
, pp. 299-305
-
-
Youssef, K.K.1
-
50
-
-
78651467232
-
Basal cell carcinomas arise from hair follicle stem cells in Ptch1+/-mice
-
Wang, G. Y., Wang, J., Mancianti, M. L. & Epstein, E. H. Jr. Basal cell carcinomas arise from hair follicle stem cells in Ptch1+/-mice. Cancer Cell 19, 114-124 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 114-124
-
-
Wang, G.Y.1
Wang, J.2
Mancianti, M.L.3
Epstein Jr., E.H.4
-
51
-
-
0031823908
-
Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression
-
DOI 10.1002/(SICI)1097-0215(19980812)77:4<640::AID-IJC26>3.0.CO;2-8
-
Lifsted, T. et al. Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression. Int. J. Cancer 77, 640-644 (1998). (Pubitemid 28340915)
-
(1998)
International Journal of Cancer
, vol.77
, Issue.4
, pp. 640-644
-
-
Lifsted, T.1
Le Voyer, T.2
Williams, M.3
Muller, W.4
Klein-Szanto, A.5
Buetow, K.H.6
Hunter, K.W.7
-
52
-
-
0037994177
-
Genetic background is an important determinant of metastatic potential
-
Hunter, K., Welch, D. R. & Liu, E. T. Genetic background is an important determinant of metastatic potential. Nature Genet. 34, 23-24(2003).
-
(2003)
Nature Genet.
, vol.34
, pp. 23-24
-
-
Hunter, K.1
Welch, D.R.2
Liu, E.T.3
-
53
-
-
0035893391
-
Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1
-
Hunter, K. W. et al. Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1. Cancer Res. 61, 8866-8872 (2001). (Pubitemid 34013902)
-
(2001)
Cancer Research
, vol.61
, Issue.24
, pp. 8866-8872
-
-
Hunter, K.W.1
Broman, K.W.2
Le Voyer, T.3
Lukes, L.4
Cozma, D.5
Debies, M.T.6
Rouse, J.7
Welch, D.R.8
-
54
-
-
25844511053
-
Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1
-
Park, Y. G. et al. Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1. Nature Genet. 37, 1055-1062 (2005).
-
(2005)
Nature Genet.
, vol.37
, pp. 1055-1062
-
-
Park, Y.G.1
-
55
-
-
0034601487
-
Genomic analysis of metastasis reveals an essential role for RhoC
-
DOI 10.1038/35020106
-
Clark, E. A., Golub, T. R., Lander, E. S. & Hynes, R. O. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 406, 532-535 (2000). (Pubitemid 30625739)
-
(2000)
Nature
, vol.406
, Issue.6795
, pp. 532-535
-
-
Clark, E.A.1
Golub, T.R.2
Lander, E.S.3
Hynes, R.O.4
-
56
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
DOI 10.1016/j.cell.2004.06.006, PII S0092867404005768
-
Yang, J. et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117, 927-939 (2004). (Pubitemid 38798858)
-
(2004)
Cell
, vol.117
, Issue.7
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Savagner, P.7
Gitelman, I.8
Richardson, A.9
Weinberg, R.A.10
-
57
-
-
34249847158
-
In vivo selection for metastasis promoting genes in the mouse
-
DOI 10.1073/pnas.0701145104
-
Gumireddy, K. et al. In vivo selection for metastasis promoting genes in the mouse. Proc. Natl Acad. Sci. USA 104, 6696-6701 (2007). (Pubitemid 47175563)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.16
, pp. 6696-6701
-
-
Gumireddy, K.1
Sun, F.2
Klein-Szanto, A.J.3
Gibbins, J.M.4
Gimotty, P.A.5
Saunders, A.J.6
Schultz, P.G.7
Huang, Q.8
-
58
-
-
79952072718
-
Metastasis suppressors and the tumor microenvironment
-
Cook, L. M., Hurst, D. R. & Welch, D. R. Metastasis suppressors and the tumor microenvironment. Semin. Cancer Biol. 21, 113-122 (2011).
-
(2011)
Semin. Cancer Biol.
, vol.21
, pp. 113-122
-
-
Cook, L.M.1
Hurst, D.R.2
Welch, D.R.3
-
59
-
-
63049117518
-
Learning therapeutic lessons from metastasis suppressor proteins
-
Smith, S. C. & Theodorescu, D. Learning therapeutic lessons from metastasis suppressor proteins. Nature Rev. Cancer 9, 253-264 (2009).
-
(2009)
Nature Rev. Cancer
, vol.9
, pp. 253-264
-
-
Smith, S.C.1
Theodorescu, D.2
-
60
-
-
0023937268
-
Evidence for a novel gene associated with low tumor metastatic potential
-
Steeg, P. S. et al. Evidence for a novel gene associated with low tumor metastatic potential. J. Natl Cancer Inst. 80, 200-204 (1988).
-
(1988)
J. Natl Cancer Inst.
, vol.80
, pp. 200-204
-
-
Steeg, P.S.1
-
61
-
-
57849134562
-
MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer
-
Hu, G. et al. MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell 15, 9-20 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 9-20
-
-
Hu, G.1
-
62
-
-
33745288277
-
Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene
-
DOI 10.1016/j.cell.2006.06.008, PII S0092867406007185
-
Kim, M. et al. Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell 125, 1269-1281 (2006). (Pubitemid 43949521)
-
(2006)
Cell
, vol.125
, Issue.7
, pp. 1269-1281
-
-
Kim, M.1
Gans, J.D.2
Nogueira, C.3
Wang, A.4
Paik, J.-H.5
Feng, B.6
Brennan, C.7
Hahn, W.C.8
Cordon-Cardo, C.9
Wagner, S.N.10
Flotte, T.J.11
Duncan, L.M.12
Granter, S.R.13
Chin, L.14
-
63
-
-
34547926839
-
LKB1 modulates lung cancer differentiation and metastasis
-
DOI 10.1038/nature06030, PII NATURE06030
-
Ji, H. et al. LKB1 modulates lung cancer differentiation and metastasis. Nature 448, 807-810 (2007). (Pubitemid 47266337)
-
(2007)
Nature
, vol.448
, Issue.7155
, pp. 807-810
-
-
Ji, H.1
Ramsey, M.R.2
Hayes, D.N.3
Fan, C.4
McNamara, K.5
Kozlowski, P.6
Torrice, C.7
Wu, M.C.8
Shimamura, T.9
Perera, S.A.10
Liang, M.-C.11
Cai, D.12
Naumov, G.N.13
Bao, L.14
Contreras, C.M.15
Li, D.16
Chen, L.17
Krishnamurthy, J.18
Koivunen, J.19
Chirieac, L.R.20
Padera, R.F.21
Bronson, R.T.22
Lindeman, N.I.23
Christiani, D.C.24
Lin, X.25
Shapiro, G.I.26
Janne, P.A.27
Johnson, B.E.28
Meyerson, M.29
Kwiatkowski, D.J.30
Castrillon, D.H.31
Bardeesy, N.32
Sharpless, N.E.33
Wong, K.-K.34
more..
-
64
-
-
77953238558
-
Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors
-
Carretero, J. et al. Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors. Cancer Cell 17, 547-559 (2010).
-
(2010)
Cancer Cell
, vol.17
, pp. 547-559
-
-
Carretero, J.1
-
65
-
-
77956838065
-
Advances in understanding cancer genomes through second-generation sequencing
-
Meyerson, M., Gabriel, S. & Getz, G. Advances in understanding cancer genomes through second-generation sequencing. Nature Rev. Genet. 11, 685-696 (2010).
-
(2010)
Nature Rev. Genet.
, vol.11
, pp. 685-696
-
-
Meyerson, M.1
Gabriel, S.2
Getz, G.3
-
66
-
-
79954672317
-
Genome structural variation discovery and genotyping
-
Alkan, C., Coe, B. P. & Eichler, E. E. Genome structural variation discovery and genotyping. Nature Rev. Genet. 12, 363-376 (2011).
-
(2011)
Nature Rev. Genet.
, vol.12
, pp. 363-376
-
-
Alkan, C.1
Coe, B.P.2
Eichler, E.E.3
-
67
-
-
34547566118
-
CanPredict: A computational tool for predicting cancer-associated missense mutations
-
Kaminker, J. S., Zhang, Y., Watanabe, C. & Zhang, Z. CanPredict: a computational tool for predicting cancer-associated missense mutations. Nucleic Acids Res. 35, W595-W598 (2007).
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Kaminker, J.S.1
Zhang, Y.2
Watanabe, C.3
Zhang, Z.4
-
68
-
-
0035026704
-
Predicting deleterious amino acid substitutions
-
DOI 10.1101/gr.176601
-
Ng, P. C. & Henikoff, S. Predicting deleterious amino acid substitutions. Genome Res. 11, 863-874 (2001). (Pubitemid 32447869)
-
(2001)
Genome Research
, vol.11
, Issue.5
, pp. 863-874
-
-
Ng, P.C.1
Henikoff, S.2
-
69
-
-
77951640946
-
A method and server for predicting damaging missense mutations
-
Adzhubei, I. A. et al. A method and server for predicting damaging missense mutations. Nature Methods 7, 248-249 (2010).
-
(2010)
Nature Methods
, vol.7
, pp. 248-249
-
-
Adzhubei, I.A.1
-
70
-
-
67049095042
-
Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry
-
Leth-Larsen, R. et al. Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry. Mol. Cell. Proteomics 8, 1436-1449 (2009).
-
(2009)
Mol. Cell. Proteomics
, vol.8
, pp. 1436-1449
-
-
Leth-Larsen, R.1
-
71
-
-
67349199945
-
Identification of metastasis associated proteins in human lung squamous carcinoma using two-dimensional difference gel electrophoresis and laser capture microdissection
-
Yao, H. et al. Identification of metastasis associated proteins in human lung squamous carcinoma using two-dimensional difference gel electrophoresis and laser capture microdissection. Lung Cancer 65, 41-48 (2009).
-
(2009)
Lung Cancer
, vol.65
, pp. 41-48
-
-
Yao, H.1
-
72
-
-
67349197265
-
Identification of 14-3-3 sigma as a lymph node metastasis-related protein in human lung squamous carcinoma
-
Li, D. J. et al. Identification of 14-3-3 sigma as a lymph node metastasis-related protein in human lung squamous carcinoma. Cancer Lett. 279, 65-73 (2009).
-
(2009)
Cancer Lett.
, vol.279
, pp. 65-73
-
-
Li, D.J.1
-
73
-
-
73649116726
-
Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach
-
Xue, H. et al. Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach. J. Proteome Res. 9, 545-555 (2010).
-
(2010)
J. Proteome Res.
, vol.9
, pp. 545-555
-
-
Xue, H.1
-
74
-
-
77649115961
-
Differential protein expression on the cell surface of colorectal cancer cells associated to tumor metastasis
-
Luque-Garcia, J. L. et al. Differential protein expression on the cell surface of colorectal cancer cells associated to tumor metastasis. Proteomics 10, 940-952 (2010).
-
(2010)
Proteomics
, vol.10
, pp. 940-952
-
-
Luque-Garcia, J.L.1
-
75
-
-
60149091657
-
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
-
Sreekumar, A. et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature 457, 910-914 (2009).
-
(2009)
Nature
, vol.457
, pp. 910-914
-
-
Sreekumar, A.1
-
76
-
-
53849144620
-
Strategies for discovering novel cancer biomarkers through utilization of emerging technologies
-
Kulasingam, V. & Diamandis, E. P. Strategies for discovering novel cancer biomarkers through utilization of emerging technologies. Nature Clin. Pract. Oncol. 5, 588-599 (2008).
-
(2008)
Nature Clin. Pract. Oncol.
, vol.5
, pp. 588-599
-
-
Kulasingam, V.1
Diamandis, E.P.2
-
77
-
-
0036718796
-
Clinical proteomics: Translating benchside promise into bedside reality
-
DOI 10.1038/nrd891
-
Petricoin, E. F., Zoon, K. C., Kohn, E. C., Barrett, J. C. & Liotta, L. A. Clinical proteomics: translating benchside promise into bedside reality. Nature Rev. Drug Discovery 1, 683-695 (2002). (Pubitemid 37361543)
-
(2002)
Nature Reviews Drug Discovery
, vol.1
, Issue.9
, pp. 683-695
-
-
Petricoin, E.F.1
Zoon, K.C.2
Kohn, E.C.3
Barrett, J.C.4
Liotta, L.A.5
-
78
-
-
77957667140
-
A human MAP kinase interactome
-
Bandyopadhyay, S. et al. A human MAP kinase interactome. Nature Methods 7, 801-805 (2010).
-
(2010)
Nature Methods
, vol.7
, pp. 801-805
-
-
Bandyopadhyay, S.1
-
79
-
-
67349197831
-
Molecular imaging of phosphorylation events for drug development
-
Chan, C. T., Paulmurugan, R., Reeves, R. E., Solow-Cordero, D. & Gambhir, S. S. Molecular imaging of phosphorylation events for drug development. Mol. Imaging Biol. 11, 144-158 (2009).
-
(2009)
Mol. Imaging Biol.
, vol.11
, pp. 144-158
-
-
Chan, C.T.1
Paulmurugan, R.2
Reeves, R.E.3
Solow-Cordero, D.4
Gambhir, S.S.5
-
80
-
-
33749335282
-
The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
-
DOI 10.1126/science.1132939
-
Lamb, J. et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313, 1929-1935 (2006). (Pubitemid 44497995)
-
(2006)
Science
, vol.313
, Issue.5795
, pp. 1929-1935
-
-
Lamb, J.1
Crawford, E.D.2
Peck, D.3
Modell, J.W.4
Blat, I.C.5
Wrobel, M.J.6
Lerner, J.7
Brunet, J.-P.8
Subramanian, A.9
Ross, K.N.10
Reich, M.11
Hieronymus, H.12
Wei, G.13
Armstrong, S.A.14
Haggarty, S.J.15
Clemons, P.A.16
Wei, R.17
Carr, S.A.18
Lander, E.S.19
Golub, T.R.20
more..
-
81
-
-
77957936826
-
Downregulation of p53-inducible microRNAs 192,194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development
-
Pichiorri, F. et al. Downregulation of p53-inducible microRNAs 192,194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development. Cancer Cell 18, 367-381 (2010).
-
(2010)
Cancer Cell
, vol.18
, pp. 367-381
-
-
Pichiorri, F.1
-
82
-
-
44449149903
-
Genetic and epigenetic silencing of MicroRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression
-
DOI 10.1016/j.ccr.2008.04.018, PII S1535610808001530
-
Bueno, M. J. et al. Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression. Cancer Cell 13, 496-506 (2008). (Pubitemid 351763902)
-
(2008)
Cancer Cell
, vol.13
, Issue.6
, pp. 496-506
-
-
Bueno, M.J.1
Perez De Castro, I.2
Gomez De Cedron, M.3
Santos, J.4
Calin, G.A.5
Cigudosa, JuanC.6
Croce, C.M.7
Fernandez-Piqueras, J.8
Malumbres, M.9
-
83
-
-
35748979703
-
Epigenetic Silencing of the Myelopoiesis Regulator microRNA-223 by the AML1/ETO Oncoprotein
-
DOI 10.1016/j.ccr.2007.09.020, PII S1535610807002681
-
Fazi, F. et al. Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. Cancer Cell 12, 457-466 (2007). (Pubitemid 350046404)
-
(2007)
Cancer Cell
, vol.12
, Issue.5
, pp. 457-466
-
-
Fazi, F.1
Racanicchi, S.2
Zardo, G.3
Starnes, L.M.4
Mancini, M.5
Travaglini, L.6
Diverio, D.7
Ammatuna, E.8
Cimino, G.9
Lo-Coco, F.10
Grignani, F.11
Nervi, C.12
-
84
-
-
58149239686
-
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
-
Varambally, S. et al. Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 322, 1695-1699 (2008).
-
(2008)
Science
, vol.322
, pp. 1695-1699
-
-
Varambally, S.1
-
85
-
-
70350778443
-
An epigenetic switch involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
-
Iliopoulos, D., Hirsch, H. A. & Struhl, K. An epigenetic switch involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 139, 693-706 (2009).
-
(2009)
Cell
, vol.139
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
86
-
-
35148886434
-
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
-
DOI 10.1038/nature06174, PII NATURE06174
-
Ma, L., Teruya-Feldstein, J. & Weinberg, R. A. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449, 682-688 (2007). (Pubitemid 47552092)
-
(2007)
Nature
, vol.449
, Issue.7163
, pp. 682-688
-
-
Ma, L.1
Teruya-Feldstein, J.2
Weinberg, R.A.3
-
87
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
Tavazoie, S. F. et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451, 147-152 (2008).
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
-
88
-
-
63049085576
-
MicroRNAs - The micro steering wheel of tumour metastases
-
Nicoloso, M. S., Spizzo, R., Shimizu, M., Rossi, S. & Calin, G. A. MicroRNAs-the micro steering wheel of tumour metastases. Nature Rev. Cancer 9, 293-302 (2009).
-
(2009)
Nature Rev. Cancer
, vol.9
, pp. 293-302
-
-
Nicoloso, M.S.1
Spizzo, R.2
Shimizu, M.3
Rossi, S.4
Calin, G.A.5
-
89
-
-
80052470207
-
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
-
Korpal, M. et al. Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nature Med. 17, 1101-1108 (2011).
-
(2011)
Nature Med.
, vol.17
, pp. 1101-1108
-
-
Korpal, M.1
-
90
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek, D. et al. The impact of microRNAs on protein output. Nature 455, 64-71 (2008).
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
-
91
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of-target mRNAs
-
DOI 10.1038/nature03315
-
Lim, L. P. et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433, 769-773 (2005). (Pubitemid 40292988)
-
(2005)
Nature
, vol.433
, Issue.7027
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
Castle, J.6
Bartel, D.P.7
Linsley, P.S.8
Johnson, J.M.9
-
92
-
-
77951118936
-
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
-
Gupta, R. A. et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 464, 1071-1076 (2010).
-
(2010)
Nature
, vol.464
, pp. 1071-1076
-
-
Gupta, R.A.1
-
93
-
-
79953034492
-
Epigenetics: Unravelling the cancer code
-
Brower, V. Epigenetics: unravelling the cancer code. Nature 471, S12-S13 (2011).
-
(2011)
Nature
, vol.471
-
-
Brower, V.1
-
94
-
-
40849139208
-
Epigenetics in cancer
-
Esteller, M. Epigenetics in cancer. N. Engl. J. Med. 358, 1148-1159 (2008).
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
95
-
-
33847065486
-
The epigenomics of cancer
-
DOI 10.1016/j.cell.2007.01.029, PII S0092867407001274
-
Jones, P. A. & Baylin, S. B. The epigenomics of cancer. Cell 128, 683-692 (2007). (Pubitemid 46273572)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
96
-
-
77957351501
-
Induction of epigenetic alterations by chronic inflammation and its significance on carcinogenesis
-
Niwa, T. & Ushijima, T. Induction of epigenetic alterations by chronic inflammation and its significance on carcinogenesis. Adv. Genet. 71, 41-56 (2010).
-
(2010)
Adv. Genet.
, vol.71
, pp. 41-56
-
-
Niwa, T.1
Ushijima, T.2
-
97
-
-
79953650663
-
Distinct profiles of epigenetic evolution between colorectal cancers with and without metastasis
-
Ju, H. X. et al. Distinct profiles of epigenetic evolution between colorectal cancers with and without metastasis. Am. J. Pathol. 178, 1835-1846 (2011).
-
(2011)
Am. J. Pathol.
, vol.178
, pp. 1835-1846
-
-
Ju, H.X.1
-
98
-
-
78649776849
-
Computational micromodel for epigenetic mechanisms
-
Raghavan, K., Ruskin, H. J., Perrin, D., Goasmat, F. & Burns, J. Computational micromodel for epigenetic mechanisms. PLoS ONE 5, e14031 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Raghavan, K.1
Ruskin, H.J.2
Perrin, D.3
Goasmat, F.4
Burns, J.5
-
99
-
-
63049121364
-
The metastatic niche: Adapting the foreign soil
-
Psaila, B. & Lyden, D. The metastatic niche: adapting the foreign soil. Nature Rev. Cancer 9, 285-293 (2009).
-
(2009)
Nature Rev. Cancer
, vol.9
, pp. 285-293
-
-
Psaila, B.1
Lyden, D.2
-
100
-
-
0035495401
-
Putting tumours in context
-
Bissell, M. J. & Radisky, D. Putting tumours in context. Nature Rev. Cancer 1, 46-54 (2001). (Pubitemid 33741880)
-
(2001)
Nature Reviews Cancer
, vol.1
, Issue.1
, pp. 46-54
-
-
Bissell, M.J.1
Radisky, D.2
-
101
-
-
33745515023
-
Tumour microenvironment - TGFΒ: The molecular Jekyll and Hyde of cancer
-
DOI 10.1038/nrc1926, PII N1926
-
Bierie, B. & Moses, H. L. Tumour microenvironment: TGFβ: the molecular Jekyll and Hyde of cancer. Nature Rev. Cancer 6, 506-520 (2006). (Pubitemid 43980540)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.7
, pp. 506-520
-
-
Bierie, B.1
Moses, H.L.2
-
102
-
-
0037052448
-
Development: Stromal effects on mammary gland development and breast cancer
-
DOI 10.1126/science.1067431
-
Wiseman, B. S. & Werb, Z. Stromal effects on mammary gland development and breast cancer. Science 296, 1046-1049 (2002). (Pubitemid 34517108)
-
(2002)
Science
, vol.296
, Issue.5570
, pp. 1046-1049
-
-
Wiseman, B.S.1
Werb, Z.2
-
103
-
-
0037276432
-
Extracellular matrix-stromal cell contribution to neoplastic phenotype of epithelial cells in the breast
-
DOI 10.1186/bcr580
-
Shekhar, M. P., Pauley, R. & Heppner, G. Host microenvironment in breast cancer development: extracellular matrix-stromal cell contribution to neoplastic phenotype of epithelial cells in the breast. Breast Cancer Res. 5, 130-135 (2003). (Pubitemid 36519405)
-
(2003)
Breast Cancer Research
, vol.5
, Issue.3
, pp. 130-135
-
-
Shekhar, M.P.V.1
Pauley, R.2
Heppner, G.3
-
104
-
-
0035253742
-
Know thy neighbor: Stromal cells can contribute oncogenic signals
-
DOI 10.1016/S0959-437X(00)00156-8
-
Tlsty, T. D. & Hein, P. W. Know thy neighbor: stromal cells can contribute oncogenic signals. Curr. Opin. Genet. Dev. 11, 54-59 (2001). (Pubitemid 32119278)
-
(2001)
Current Opinion in Genetics and Development
, vol.11
, Issue.1
, pp. 54-59
-
-
Tlsty, T.D.1
Hein, P.W.2
-
105
-
-
79751501829
-
Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth
-
Quante, M. et al. Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth. Cancer Cell 19, 257-272 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 257-272
-
-
Quante, M.1
-
106
-
-
33645739790
-
Tumor stroma and regulation of cancer development
-
Tlsty, T. D. & Coussens, L. M. Tumor stroma and regulation of cancer development. Annu. Rev. Pathol. 1, 119-150 (2006).
-
(2006)
Annu. Rev. Pathol.
, vol.1
, pp. 119-150
-
-
Tlsty, T.D.1
Coussens, L.M.2
-
107
-
-
46949084994
-
Biomarkers of angiogenesis for the development of antiangiogenic therapies in oncology: Tools or decorations?
-
DOI 10.1038/ncponc1150, PII NCPONC1150
-
Sessa, C., Guibal, A., Del Conte, G. & Ruegg, C. Biomarkers of angiogenesis for the development of antiangiogenic therapies in oncology: tools or decorations? Nature Clin. Pract. Oncol. 5, 378-391 (2008). (Pubitemid 351958963)
-
(2008)
Nature Clinical Practice Oncology
, vol.5
, Issue.7
, pp. 378-391
-
-
Sessa, C.1
Guibal, A.2
Del Conte, G.3
Ruegg, C.4
-
108
-
-
43149102244
-
Drug Insight: Antiangiogenic therapies for gastrointestinal cancers - Focus on monoclonal antibodies
-
DOI 10.1038/ncpgasthep1097, PII NCPGASTHEP1097
-
Reinacher-Schick, A., Pohl, M. & Schmiegel, W. Drug insight: antiangiogenic therapies for gastrointestinal cancers-focus on monoclonal antibodies. Nature Clin. Pract. Gastroenterol. Hepatol. 5, 250-267 (2008). (Pubitemid 351637911)
-
(2008)
Nature Clinical Practice Gastroenterology and Hepatology
, vol.5
, Issue.5
, pp. 250-267
-
-
Reinacher-Schick, A.1
Pohl, M.2
Schmiegel, W.3
-
109
-
-
34548462626
-
Mechanisms of Disease: Angiogenesis and the management of breast cancer
-
DOI 10.1038/ncponc0905, PII NCPONC0905
-
Banerjee, S., Dowsett, M., Ashworth, A. & Martin, L. A. Mechanisms of disease: angiogenesis and the management of breast cancer. Nature Clin. Pract. Oncol. 4, 536-550 (2007). (Pubitemid 47351464)
-
(2007)
Nature Clinical Practice Oncology
, vol.4
, Issue.9
, pp. 536-550
-
-
Banerjee, S.1
Dowsett, M.2
Ashworth, A.3
Martin, L.-A.4
-
110
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller, K. et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N. Engl. J. Med. 357, 2666-2676 (2007).
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
-
111
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos, J. M. et al. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15, 232-239 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 232-239
-
-
Ebos, J.M.1
-
112
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes, M. et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15, 220-231 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
-
113
-
-
79953874259
-
RIBBON-1: Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer
-
Robert, N. J. et al. RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer. J. Clin. Oncol. 29, 1252-1260 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 1252-1260
-
-
Robert, N.J.1
-
114
-
-
77954700380
-
Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
-
Miles, D. W. et al. Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. J. Clin. Oncol. 28, 3239-3247 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 3239-3247
-
-
Miles, D.W.1
-
115
-
-
79951983770
-
Disease course patterns after discontinuation of bevacizumab: Pooled analysis of randomized phase III trials
-
Miles, D. et al. Disease course patterns after discontinuation of bevacizumab: pooled analysis of randomized phase III trials. J. Clin. Oncol. 29, 83-88 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 83-88
-
-
Miles, D.1
-
116
-
-
79958054544
-
Targeted therapies: Peaking beneath the surface of recent bevacizumab trials
-
Gonzalez-Angulo, A. M., Hortobagyi, G. N. & Ellis, L. M. Targeted therapies: peaking beneath the surface of recent bevacizumab trials. Nature Rev. Clin. Oncol. 8, 319-320 (2011).
-
(2011)
Nature Rev. Clin. Oncol.
, vol.8
, pp. 319-320
-
-
Gonzalez-Angulo, A.M.1
Hortobagyi, G.N.2
Ellis, L.M.3
-
117
-
-
4944229701
-
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
-
DOI 10.1158/0008-5472.CAN-04-1449
-
Wyckoff, J. et al. A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res. 64, 7022-7029 (2004). (Pubitemid 39331012)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7022-7029
-
-
Wyckoff, J.1
Wang, W.2
Lin, E.Y.3
Wang, Y.4
Pixley, F.5
Stanley, E.R.6
Graf, T.7
Pollard, J.W.8
Segall, J.9
Condeelis, J.10
-
118
-
-
31044433663
-
Macrophages: Obligate partners for tumor cell migration, invasion, and metastasis
-
DOI 10.1016/j.cell.2006.01.007, PII S0092867406000559
-
Condeelis, J. & Pollard, J. W. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell 124, 263-266 (2006). (Pubitemid 43121975)
-
(2006)
Cell
, vol.124
, Issue.2
, pp. 263-266
-
-
Condeelis, J.1
Pollard, J.W.2
-
119
-
-
78651461701
-
HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF
-
Rolny, C. et al. HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF. Cancer Cell 19, 31-44 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 31-44
-
-
Rolny, C.1
-
120
-
-
79953747613
-
CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3
-
Chen, J. et al. CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3. Cancer Cell 19, 541-555 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 541-555
-
-
Chen, J.1
-
121
-
-
79953327275
-
Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization
-
Erez, N. & Coussens, L. M. Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization. Int. J. Cancer 128, 2536-2544 (2011).
-
(2011)
Int. J. Cancer
, vol.128
, pp. 2536-2544
-
-
Erez, N.1
Coussens, L.M.2
-
122
-
-
67651160649
-
CD4+ T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
-
DeNardo, D. G. et al. CD4+ T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16, 91-102 (2009).
-
(2009)
Cancer Cell
, vol.16
, pp. 91-102
-
-
Denardo, D.G.1
-
123
-
-
79958696667
-
Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3Kγ, a single convergent point promoting tumor inflammation and progression
-
Schmid, M. C. et al. Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3Kγ, a single convergent point promoting tumor inflammation and progression. Cancer Cell 19, 715-727 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 715-727
-
-
Schmid, M.C.1
-
124
-
-
79751511326
-
A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer
-
Calbo, J. et al. A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer. Cancer Cell 19, 244-256 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 244-256
-
-
Calbo, J.1
-
125
-
-
79251478398
-
Contribution of platelets to tumour metastasis
-
Gay, L. J. & Felding-Habermann, B. Contribution of platelets to tumour metastasis. Nature Rev. Cancer 11, 123-134 (2011).
-
(2011)
Nature Rev. Cancer
, vol.11
, pp. 123-134
-
-
Gay, L.J.1
Felding-Habermann, B.2
-
126
-
-
6044259206
-
Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases
-
DOI 10.1158/1078-0432.CCR-04-0378
-
Allard, W. J. et al. Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases. Clin. Cancer Res. 10, 6897-6904 (2004). (Pubitemid 39383039)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.20
, pp. 6897-6904
-
-
Allard, W.J.1
Matera, J.2
Miller, M.C.3
Repollet, M.4
Connelly, M.C.5
Rao, C.6
Tibbe, A.G.J.7
Uhr, J.W.8
Terstappen, L.W.M.M.9
-
127
-
-
37549002543
-
Isolation of rare circulating tumour cells in cancer patients by microchip technology
-
Nagrath, S. et al. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 450, 1235-1239 (2007).
-
(2007)
Nature
, vol.450
, pp. 1235-1239
-
-
Nagrath, S.1
-
128
-
-
33845914033
-
The clinical significance of disseminated tumor cells in breast cancer
-
DOI 10.1038/ncponc0685, PII NCPONC0685
-
Slade, M. J. & Coombes, R. C. The clinical significance of disseminated tumor cells in breast cancer. Nature Clin. Pract. Oncol. 4, 30-41 (2007). (Pubitemid 46017692)
-
(2007)
Nature Clinical Practice Oncology
, vol.4
, Issue.1
, pp. 30-41
-
-
Slade, M.J.1
Combes, R.C.2
-
129
-
-
23944466427
-
A pooled analysis of bone marrow micrometastasis in breast cancer
-
DOI 10.1056/NEJMoa050434
-
Braun, S. et al. A pooled analysis of bone marrow micrometastasis in breast cancer. N. Engl. J. Med. 353, 793-802 (2005). (Pubitemid 41215488)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.8
, pp. 793-802
-
-
Braun, S.1
Vogl, F.D.2
Naume, B.3
Janni, W.4
Osborne, M.P.5
Coombes, R.C.6
Schlimok, G.7
Diel, I.J.8
Gerber, B.9
Gebauer, G.10
Pierga, J.-Y.11
Marth, C.12
Oruzio, D.13
Wiedswang, G.14
Solomayer, E.-F.15
Kundt, G.16
Strobl, B.17
Fehm, T.18
Wong, G.Y.C.19
Bliss, J.20
Vincent-Salomon, A.21
Pantel, K.22
more..
-
130
-
-
0344667589
-
Classification of Isolated Tumor Cells: Clarification of the 6th Edition of the American Joint Committee on Cancer Staging Manual
-
DOI 10.1002/cncr.11865
-
Singletary, S. E., Greene, F. L. & Sobin, L. H. Classification of isolated tumor cells: clarification of the 6th edition of the American Joint Committee on Cancer Staging Manual. Cancer 98, 2740-2741 (2003). (Pubitemid 37509544)
-
(2003)
Cancer
, vol.98
, Issue.12
, pp. 2740-2741
-
-
Singletary, S.E.1
Greene, F.L.2
Sobin, L.H.3
-
131
-
-
36849069347
-
American society of clinical oncology 2007 update of recommendations for the use of tumor markers in breast cancer
-
DOI 10.1200/JCO.2007.14.2364
-
Harris, L. et al. American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. J. Clin. Oncol. 25, 5287-5312 (2007). (Pubitemid 350232263)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.33
, pp. 5287-5312
-
-
Harris, L.1
Fritsche, H.2
Mennel, R.3
Norton, L.4
Ravdin, P.5
Taube, S.6
Somerfield, M.R.7
Hayes, D.F.8
Bast Jr., R.C.9
-
132
-
-
47949114668
-
Detection of mutations in EGFR in circulating lung-cancer cells
-
Maheswaran, S. et al. Detection of mutations in EGFR in circulating lung-cancer cells. N. Engl. J. Med. 359, 366-377 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 366-377
-
-
Maheswaran, S.1
-
133
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
DOI 10.1038/nature04186
-
Kaplan, R. N. et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438, 820-827 (2005). (Pubitemid 41753060)
-
(2005)
Nature
, vol.438
, Issue.7069
, pp. 820-827
-
-
Kaplan, R.N.1
Riba, R.D.2
Zacharoulis, S.3
Bramley, A.H.4
Vincent, L.5
Costa, C.6
MacDonald, D.D.7
Jin, D.K.8
Shido, K.9
Kerns, S.A.10
Zhu, Z.11
Hicklin, D.12
Wu, Y.13
Port, J.L.14
Altorki, N.15
Port, E.R.16
Ruggero, D.17
Shmelkov, S.V.18
Jensen, K.K.19
Rafii, S.20
Lyden, D.21
more..
-
134
-
-
79958065859
-
Clinical implications of cancer self-seeding
-
Comen, E., Norton, L. & Massague, J. Clinical implications of cancer self-seeding. Nature Rev. Clin. Oncol. 8, 369-377 (2011).
-
(2011)
Nature Rev. Clin. Oncol.
, vol.8
, pp. 369-377
-
-
Comen, E.1
Norton, L.2
Massague, J.3
-
135
-
-
72249093615
-
Tumor self-seeding by circulating cancer cells
-
Kim, M. Y. et al. Tumor self-seeding by circulating cancer cells. Cell 139, 1315-1326 (2009).
-
(2009)
Cell
, vol.139
, pp. 1315-1326
-
-
Kim, M.Y.1
-
136
-
-
33751504690
-
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
-
DOI 10.1038/ncb1507, PII NCB1507
-
Hiratsuka, S., Watanabe, A., Aburatani, H. & Maru, Y. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nature Cell Biol. 8, 1369-1375 (2006). (Pubitemid 44835111)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.12
, pp. 1369-1375
-
-
Hiratsuka, S.1
Watanabe, A.2
Aburatani, H.3
Maru, Y.4
-
137
-
-
55549128598
-
The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase
-
Hiratsuka, S. et al. The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase. Nature Cell Biol. 10, 1349-1355 (2008).
-
(2008)
Nature Cell Biol.
, vol.10
, pp. 1349-1355
-
-
Hiratsuka, S.1
-
138
-
-
77950690023
-
Interleukin-6 in bone metastasis and cancer progression
-
Ara, T. & Declerck, Y. A. Interleukin-6 in bone metastasis and cancer progression. Eur. J. Cancer 46, 1223-1231 (2010).
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 1223-1231
-
-
Ara, T.1
Declerck, Y.A.2
-
139
-
-
79951672873
-
Interaction between lung cancer cells and astrocytes via specific inflammatory cytokines in the microenvironment of brain metastasis
-
Seike, T. et al. Interaction between lung cancer cells and astrocytes via specific inflammatory cytokines in the microenvironment of brain metastasis. Clin. Exp. Metastasis 28, 13-25 (2011).
-
(2011)
Clin. Exp. Metastasis
, vol.28
, pp. 13-25
-
-
Seike, T.1
-
140
-
-
79751472667
-
Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
-
Sethi, N., Dai, X., Winter, C. G. & Kang, Y. Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell 19, 192-205 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 192-205
-
-
Sethi, N.1
Dai, X.2
Winter, C.G.3
Kang, Y.4
-
141
-
-
58249095935
-
Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells
-
Ara, T. et al. Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res. 69, 329-337 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 329-337
-
-
Ara, T.1
-
142
-
-
77956630507
-
Interfering with inflammation: A new strategy to block breast cancer self-renewal and progression?
-
Cabodi, S. & Taverna, D. Interfering with inflammation: a new strategy to block breast cancer self-renewal and progression? Breast Cancer Res. 12, 305 (2010).
-
(2010)
Breast Cancer Res.
, vol.12
, pp. 305
-
-
Cabodi, S.1
Taverna, D.2
-
143
-
-
78650306070
-
Dysregulation of developmental pathways in bone metastasis
-
Sethi, N. & Kang, Y. Dysregulation of developmental pathways in bone metastasis. Bone 48, 16-22 (2011).
-
(2011)
Bone
, vol.48
, pp. 16-22
-
-
Sethi, N.1
Kang, Y.2
-
144
-
-
0034658725
-
Molecular mechanism of osteolytic bone metastases
-
Guise, T. A. Molecular mechanisms of osteolytic bone metastases. Cancer 88, 2892-2898 (2000). (Pubitemid 30413169)
-
(2000)
Cancer
, vol.88
, Issue.12 SUPPL.
, pp. 2892-2898
-
-
Guise, T.A.1
-
145
-
-
0032918414
-
TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
-
Yin, J. J. et al. TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J. Clin. Invest. 103, 197-206 (1999). (Pubitemid 29053137)
-
(1999)
Journal of Clinical Investigation
, vol.103
, Issue.2
, pp. 197-206
-
-
Yin, J.J.1
Selander, K.2
Chirgwin, J.M.3
Dallas, M.4
Grubbs, B.G.5
Wieser, R.6
Massague, J.7
Mundy, G.R.8
Guise, T.A.9
-
146
-
-
34548804505
-
Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer
-
DOI 10.1158/0008-5472.CAN-06-2490
-
Buijs, J. T. et al. Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. Cancer Res. 67, 8742-8751 (2007). (Pubitemid 47437450)
-
(2007)
Cancer Research
, vol.67
, Issue.18
, pp. 8742-8751
-
-
Buijs, J.T.1
Henriquez, N.V.2
Van Overveld, P.G.M.3
Van Der Horst, G.4
Que, I.5
Schwaninger, R.6
Rentsch, C.7
Ten Dijke, P.8
Cleton-Jansen, A.-M.9
Driouch, K.10
Lidereau, R.11
Bachelier, R.12
Vukicevic, S.13
Clezardin, P.14
Papapoulos, S.E.15
Cecchini, M.G.16
Lowik, C.W.G.M.17
Van Der Pluijm, G.18
-
147
-
-
36348960224
-
TGF-β and BMP7 interactions in tumour progression and bone metastasis
-
DOI 10.1007/s10585-007-9118-2
-
Buijs, J. T. et al. TGF-β and BMP7 interactions in tumour progression and bone metastasis. Clin. Exp. Metastasis 24, 609-617 (2007). (Pubitemid 50003597)
-
(2007)
Clinical and Experimental Metastasis
, vol.24
, Issue.8
, pp. 609-617
-
-
Buijs, J.T.1
Henriquez, N.V.2
Van Overveld, P.G.M.3
Van Der Horst, G.4
Ten Dijke, P.5
Van Der Pluijm, G.6
-
148
-
-
34548705794
-
BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo
-
DOI 10.2353/ajpath.2007.070168
-
Buijs, J. T. et al. BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo. Am. J. Pathol. 171, 1047-1057 (2007). (Pubitemid 47441001)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.3
, pp. 1047-1057
-
-
Buijs, J.T.1
Rentsch, C.A.2
Van Der Horst, G.3
Van Overveld, P.G.M.4
Wetterwald, A.5
Schwaninger, R.6
Henriquez, N.V.7
Ten Dijke, P.8
Borovecki, F.9
Markwalder, R.10
Thalmann, G.N.11
Papapoulos, S.E.12
Pelger, R.C.M.13
Vukicevic, S.14
Cecchini, M.G.15
Lowik, C.W.G.M.16
Van Der Pluijm, G.17
-
149
-
-
24944480253
-
Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism
-
DOI 10.1158/0008-5472.CAN-05-1891
-
Dai, J. et al. Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res. 65, 8274-8285 (2005). (Pubitemid 41330592)
-
(2005)
Cancer Research
, vol.65
, Issue.18
, pp. 8274-8285
-
-
Dai, J.1
Keller, J.2
Zhang, J.3
Lu, Y.4
Yao, Z.5
Keller, E.T.6
-
150
-
-
31544464054
-
Overexpression of noggin inhibits BMP-mediated growth of osteolytic prostate cancer lesions
-
DOI 10.1016/j.bone.2005.07.015, PII S8756328205002838
-
Feeley, B. T. et al. Overexpression of noggin inhibits BMP-mediated growth of osteolytic prostate cancer lesions. Bone 38, 154-166 (2006). (Pubitemid 43165781)
-
(2006)
Bone
, vol.38
, Issue.2
, pp. 154-166
-
-
Feeley, B.T.1
Krenek, L.2
Liu, N.3
Hsu, W.K.4
Gamradt, S.C.5
Schwarz, E.M.6
Huard, J.7
Lieberman, J.R.8
-
151
-
-
54549102135
-
Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway
-
Katsuno, Y. et al. Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway. Oncogene 27, 6322-6333 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 6322-6333
-
-
Katsuno, Y.1
-
152
-
-
47249149740
-
Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases
-
Bu, G. et al. Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases. Int. J. Cancer 123, 1034-1042 (2008).
-
(2008)
Int. J. Cancer
, vol.123
, pp. 1034-1042
-
-
Bu, G.1
-
153
-
-
4444326415
-
Up-regulation of Wnt-1 and β-catenin production in patients with advanced metastatic prostate carcinoma: Potential pathogenetic and prognostic implications
-
DOI 10.1002/cncr.20518
-
Chen, G. et al. Up-regulation of Wnt-1 and β-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications. Cancer 101, 1345-1356 (2004). (Pubitemid 39180390)
-
(2004)
Cancer
, vol.101
, Issue.6
, pp. 1345-1356
-
-
Chen, G.1
Shukeir, N.2
Potti, A.3
Sircar, K.4
Aprikian, A.5
Goltzman, D.6
Rabbani, S.A.7
-
154
-
-
48649090754
-
Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms
-
Dai, J. et al. Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms. Cancer Res. 68, 5785-5794 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 5785-5794
-
-
Dai, J.1
-
155
-
-
24744439747
-
Prostate cancer cells promote osteoblastic bone metastases through Wnts
-
DOI 10.1158/0008-5472.CAN-05-1317
-
Hall, C. L., Bafico, A., Dai, J., Aaronson, S. A. & Keller, E. T. Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Res. 65, 7554-7560 (2005). (Pubitemid 41297224)
-
(2005)
Cancer Research
, vol.65
, Issue.17
, pp. 7554-7560
-
-
Hall, C.L.1
Bafico, A.2
Dai, J.3
Aaronson, S.A.4
Keller, E.T.5
-
156
-
-
27644473781
-
Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2
-
DOI 10.1182/blood-2004-12-4940
-
Oshima, T. et al. Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2. Blood 106, 3160-3165 (2005). (Pubitemid 41565914)
-
(2005)
Blood
, vol.106
, Issue.9
, pp. 3160-3165
-
-
Oshima, T.1
Abe, M.2
Asano, J.3
Hara, T.4
Kitazoe, K.5
Sekimoto, E.6
Tanaka, Y.7
Shibata, H.8
Hashimoto, T.9
Ozaki, S.10
Kido, S.11
Inoue, D.12
Matsumoto, T.13
-
157
-
-
0346363760
-
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
-
DOI 10.1056/NEJMoa030847
-
Tian, E. et al. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N. Engl. J. Med. 349, 2483-2494 (2003). (Pubitemid 38010074)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.26
, pp. 2483-2494
-
-
Tian, E.1
Zhan, F.2
Walker, R.3
Rasmussen, E.4
Ma, Y.5
Barlogie, B.6
Shaughnessy Jr., J.D.7
-
158
-
-
54249097017
-
Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells
-
Pratap, J. et al. Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells. Cancer Res. 68, 7795-7802 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 7795-7802
-
-
Pratap, J.1
-
159
-
-
33747890209
-
The Hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells
-
DOI 10.1158/0008-5472.CAN-06-0452
-
Sterling, J. A. et al. The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells. Cancer Res. 66, 7548-7553 (2006). (Pubitemid 44289210)
-
(2006)
Cancer Research
, vol.66
, Issue.15
, pp. 7548-7553
-
-
Sterling, J.A.1
Oyajobi, B.O.2
Grubbs, B.3
Padalecki, S.S.4
Munoz, S.A.5
Gupta, A.6
Story, B.7
Zhao, M.8
Mundy, G.R.9
-
160
-
-
62849120025
-
Paracrine sonic hedgehog signalling by prostate cancer cells induces osteoblast differentiation
-
Zunich, S. M. et al. Paracrine sonic hedgehog signalling by prostate cancer cells induces osteoblast differentiation. Mol. Cancer 8, 12 (2009).
-
(2009)
Mol. Cancer
, vol.8
, pp. 12
-
-
Zunich, S.M.1
-
161
-
-
67649662201
-
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis
-
Nguyen, D. X. et al. WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell 138, 51-62 (2009).
-
(2009)
Cell
, vol.138
, pp. 51-62
-
-
Nguyen, D.X.1
-
162
-
-
79960117895
-
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
-
Oskarsson, T. et al. Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. Nature Med. 17, 867-874 (2011).
-
(2011)
Nature Med.
, vol.17
, pp. 867-874
-
-
Oskarsson, T.1
-
163
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
DOI 10.1038/nature00766
-
Davies, H. et al. Mutations of the BRAF gene in human cancer. Nature 417, 949-954 (2002). (Pubitemid 34716871)
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
Hawes, R.17
Hughes, J.18
Kosmidou, V.19
Menzies, A.20
Mould, C.21
Parker, A.22
Stevens, C.23
Watt, S.24
Hooper, S.25
Wilson, R.26
Jayatilake, H.27
Gusterson, B.A.28
Cooper, C.29
Shipley, J.30
Hargrave, D.31
Pritchard-Jones, K.32
Maitland, N.33
Chenevix-Trench, G.34
Riggins, G.J.35
Bigner, D.D.36
Palmleri, G.37
Cossu, A.38
Flanagan, A.39
Nicholson, A.40
Ho, J.W.C.41
Leung, S.Y.42
Yuen, S.T.43
Weber, B.L.44
Seigler, H.F.45
Darrow, T.L.46
Paterson, H.47
Marais, R.48
Marshall, C.J.49
Wooster, R.50
Stratton, M.R.51
Futreal, P.A.52
more..
-
164
-
-
4043139430
-
Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells. Role of BRAF mutation and fibroblast growth factor signaling
-
DOI 10.1074/jbc.M405102200
-
Huntington, J. T. et al. Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling. J. Biol. Chem. 279, 33168-33176 (2004). (Pubitemid 39062961)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.32
, pp. 33168-33176
-
-
Huntington, J.T.1
Shields, J.M.2
Der, C.J.3
Wyatt, C.A.4
Benbow, U.5
Slingluff Jr., C.L.6
Brinckerhoff, C.E.7
-
165
-
-
65549130220
-
Rnd3 regulation of the actin cytoskeleton promotes melanoma migration and invasive outgrowth in three dimensions
-
Klein, R. M. & Aplin, A. E. Rnd3 regulation of the actin cytoskeleton promotes melanoma migration and invasive outgrowth in three dimensions. Cancer Res. 69, 2224-2233 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 2224-2233
-
-
Klein, R.M.1
Aplin, A.E.2
-
166
-
-
63649083462
-
Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma
-
Old, W. M. et al. Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma. Mol. Cell 34, 115-131 (2009).
-
(2009)
Mol. Cell
, vol.34
, pp. 115-131
-
-
Old, W.M.1
-
167
-
-
78651457445
-
Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A
-
Arozarena, I. et al. Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A. Cancer Cell 19, 45-57 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 45-57
-
-
Arozarena, I.1
-
168
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty, K. T. et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N. Engl. J. Med. 363, 809-819 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 809-819
-
-
Flaherty, K.T.1
-
169
-
-
77956513286
-
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
-
Bollag, G. et al. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature 467, 596-599 (2010).
-
(2010)
Nature
, vol.467
, pp. 596-599
-
-
Bollag, G.1
-
170
-
-
73649102105
-
Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC
-
Turke, A. B. et al. Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC. Cancer Cell 17, 77-88 (2010).
-
(2010)
Cancer Cell
, vol.17
, pp. 77-88
-
-
Turke, A.B.1
-
171
-
-
46749156706
-
Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins
-
DOI 10.1172/JC134588
-
Guix, M. et al. Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins. J. Clin. Invest. 118, 2609-2619 (2008). (Pubitemid 351949788)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.7
, pp. 2609-2619
-
-
Guix, M.1
Faber, A.C.2
Wang, S.E.3
Olivares, M.G.4
Song, Y.5
Qu, S.6
Rinehart, C.7
Seidel, B.8
Yee, D.9
Arteaga, C.L.10
Engelman, J.A.11
-
172
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
DOI 10.1126/science.1141478
-
Engelman, J. A. et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316, 1039-1043 (2007). (Pubitemid 46799492)
-
(2007)
Science
, vol.316
, Issue.5827
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Joon, O.P.6
Lindeman, N.7
Gale, C.-M.8
Zhao, X.9
Christensen, J.10
Kosaka, T.11
Holmes, A.J.12
Rogers, A.M.13
Cappuzzo, F.14
Mok, T.15
Lee, C.16
Johnson, B.E.17
Cantley, L.C.18
Janne, P.A.19
-
173
-
-
78651418282
-
Mutant BRAF melanomas-dependence and resistance
-
Poulikakos, P. I. & Rosen, N. Mutant BRAF melanomas-dependence and resistance. Cancer Cell 19, 11-15 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 11-15
-
-
Poulikakos, P.I.1
Rosen, N.2
-
174
-
-
77949732073
-
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
-
Poulikakos, P. I., Zhang, C., Bollag, G., Shokat, K. M. & Rosen, N. RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF. Nature 464, 427-430 (2010).
-
(2010)
Nature
, vol.464
, pp. 427-430
-
-
Poulikakos, P.I.1
Zhang, C.2
Bollag, G.3
Shokat, K.M.4
Rosen, N.5
-
175
-
-
77949685981
-
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
-
Hatzivassiliou, G. et al. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. Nature 464, 431-435 (2010).
-
(2010)
Nature
, vol.464
, pp. 431-435
-
-
Hatzivassiliou, G.1
-
176
-
-
74849109743
-
Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF
-
Heidorn, S. J. et al. Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF. Cell 140, 209-221 (2010).
-
(2010)
Cell
, vol.140
, pp. 209-221
-
-
Heidorn, S.J.1
-
177
-
-
40749114724
-
The yin and yang of treating BRCA-deficient tumors
-
DOI 10.1016/j.cell.2008.03.006, PII S009286740800336X
-
Martin, R. W., Connell, P. P. & Bishop, D. K. The Yin and Yang of treating BRCA-deficient tumors. Cell 132, 919-920 (2008). (Pubitemid 351381752)
-
(2008)
Cell
, vol.132
, Issue.6
, pp. 919-920
-
-
Martin, R.W.1
Connell, P.P.2
Bishop, D.K.3
-
178
-
-
39849097680
-
Resistance to therapy caused by intragenic deletion in BRCA2
-
DOI 10.1038/nature06548, PII NATURE06548
-
Edwards, S. L. et al. Resistance to therapy caused by intragenic deletion in BRCA2. Nature 451, 1111-1115 (2008). (Pubitemid 351317441)
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1111-1115
-
-
Edwards, S.L.1
Brough, R.2
Lord, C.J.3
Natrajan, R.4
Vatcheva, R.5
Levine, D.A.6
Boyd, J.7
Reis-Filho, J.S.8
Ashworth, A.9
-
179
-
-
0001686739
-
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
-
DOI 10.1016/S1535-6108(02)00096-X
-
Shah, N. P. et al. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell 2, 117-125 (2002). (Pubitemid 41039112)
-
(2002)
Cancer Cell
, vol.2
, Issue.2
, pp. 117-125
-
-
Shah, N.P.1
Nicoll, J.M.2
Nagar, B.3
Gorre, M.E.4
Paquette, R.L.5
Kuriyan, J.6
Sawyers, C.L.7
-
180
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
DOI 10.1126/science.1099480
-
Shah, N. P. et al. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 305, 399-401 (2004). (Pubitemid 38938156)
-
(2004)
Science
, vol.305
, Issue.5682
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
Chen, P.4
Norris, D.5
Sawyers, C.L.6
-
181
-
-
14744274624
-
Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance
-
DOI 10.1073/pnas.0409770102
-
Burgess, M. R., Skaggs, B. J., Shah, N. P., Lee, F. Y. & Sawyers, C. L. Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance. Proc. Natl Acad. Sci. USA 102, 3395-3400 (2005). (Pubitemid 40328056)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.9
, pp. 3395-3400
-
-
Burgess, M.R.1
Skaggs, B.J.2
Shah, N.P.3
Lee, F.Y.4
Sawyers, C.L.5
-
182
-
-
78650303507
-
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
-
Nazarian, R. et al. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nature 468, 973-977 (2010).
-
(2010)
Nature
, vol.468
, pp. 973-977
-
-
Nazarian, R.1
-
183
-
-
78650309875
-
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
-
Johannessen, C. M. et al. COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature 468, 968-972 (2010).
-
(2010)
Nature
, vol.468
, pp. 968-972
-
-
Johannessen, C.M.1
-
184
-
-
77956533396
-
Therapeutic targeting of the prostate cancer microenvironment
-
Karlou, M., Tzelepi, V. & Efstathiou, E. Therapeutic targeting of the prostate cancer microenvironment. Nature Rev. Urol. 7, 494-509 (2010).
-
(2010)
Nature Rev. Urol.
, vol.7
, pp. 494-509
-
-
Karlou, M.1
Tzelepi, V.2
Efstathiou, E.3
-
185
-
-
78649857175
-
Cancer: Chemotherapy counteracted
-
Emmenegger, U. & Kerbel, R. S. Cancer: chemotherapy counteracted. Nature 468, 637-638 (2010).
-
(2010)
Nature
, vol.468
, pp. 637-638
-
-
Emmenegger, U.1
Kerbel, R.S.2
-
186
-
-
34548841964
-
+,
-
DOI 10.1101/gad.1588607
-
Williams, R. T., den Besten, W. & Sherr, C. J. Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia. Genes Dev. 21, 2283-2287 (2007). (Pubitemid 47443334)
-
(2007)
Genes and Development
, vol.21
, Issue.18
, pp. 2283-2287
-
-
Williams, R.T.1
Den Besten, W.2
Sherr, C.J.3
-
187
-
-
70350243067
-
Comparative impact of trastuzumab and cyclophosphamide on HER-2-positive human breast cancer xenografts
-
Francia, G. et al. Comparative impact of trastuzumab and cyclophosphamide on HER-2-positive human breast cancer xenografts. Clin. Cancer Res. 15, 6358-6366 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 6358-6366
-
-
Francia, G.1
-
188
-
-
0037093209
-
Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water
-
Man, S. et al. Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water. Cancer Res. 62, 2731-2735 (2002). (Pubitemid 34525751)
-
(2002)
Cancer Research
, vol.62
, Issue.10
, pp. 2731-2735
-
-
Man, S.1
Bocci, G.2
Francia, G.3
Green, S.K.4
Jothy, S.5
Hanahan, D.6
Bohlen, P.7
Hicklin, D.J.8
Bergers, G.9
Kerbel, R.S.10
-
189
-
-
79952360832
-
Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: A randomised, double-blind study
-
Fizazi, K. et al. Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study. Lancet 377, 813-822 (2011).
-
(2011)
Lancet
, vol.377
, pp. 813-822
-
-
Fizazi, K.1
-
190
-
-
79551568488
-
Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: A randomized, double-blind study
-
Stopeck, A. T. et al. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study. J. Clin. Oncol. 28, 5132-5139 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 5132-5139
-
-
Stopeck, A.T.1
-
191
-
-
77950658719
-
The HSC niche concept has turned 31 Has our knowledge matured?
-
Lymperi, S., Ferraro, F. & Scadden, D. T. The HSC niche concept has turned 31. Has our knowledge matured? Ann. N. Y Acad. Sci. 1192, 12-18 (2010).
-
(2010)
Ann. N. y Acad. Sci.
, vol.1192
, pp. 12-18
-
-
Lymperi, S.1
Ferraro, F.2
Scadden, D.T.3
-
192
-
-
79952696452
-
A rapid and scalable system for studying gene function in mice using conditional RNA interference
-
Premsrirut, P. K. et al. A rapid and scalable system for studying gene function in mice using conditional RNA interference. Cell 145, 145-158 (2011).
-
(2011)
Cell
, vol.145
, pp. 145-158
-
-
Premsrirut, P.K.1
-
193
-
-
0141569009
-
Myc-driven murine prostate cancer shares molecular features with human prostate tumors
-
DOI 10.1016/S1535-6108(03)00197-1
-
Ellwood-Yen, K. et al. Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell 4, 223-238 (2003). (Pubitemid 37163836)
-
(2003)
Cancer Cell
, vol.4
, Issue.3
, pp. 223-238
-
-
Ellwood-Yen, K.1
Graeber, T.G.2
Wongvipat, J.3
Iruela-Arispe, M.L.4
Zhang, J.5
Matusik, R.6
Thomas, G.V.7
Sawyers, C.L.8
-
194
-
-
11244258643
-
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis
-
DOI 10.1038/ng1490
-
Sweet-Cordero, A. et al. An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis. Nature Genet. 37, 48-55 (2005). (Pubitemid 40070939)
-
(2005)
Nature Genetics
, vol.37
, Issue.1
, pp. 48-55
-
-
Sweet-Cordero, A.1
Mukherjee, S.2
Subramanian, A.3
You, H.4
Roix, J.J.5
Ladd-Acosta, C.6
Mesirov, J.7
Golub, T.R.8
Jacks, T.9
-
195
-
-
11244307332
-
Cross-species comparisons of cancer signaling
-
DOI 10.1038/ng0105-7
-
Graeber, T. G. & Sawyers, C. L. Cross-species comparisons of cancer signaling. Nature Genet. 37, 7-8 (2005). (Pubitemid 40070929)
-
(2005)
Nature Genetics
, vol.37
, Issue.1
, pp. 7-8
-
-
Graeber, T.G.1
Sawyers, C.L.2
-
196
-
-
79251468712
-
Mouse models of advanced spontaneous metastasis for experimental therapeutics
-
Francia, G., Cruz-Munoz, W., Man, S., Xu, P. & Kerbel, R. S. Mouse models of advanced spontaneous metastasis for experimental therapeutics. Nature Rev. Cancer 11, 135-141 (2011).
-
(2011)
Nature Rev. Cancer
, vol.11
, pp. 135-141
-
-
Francia, G.1
Cruz-Munoz, W.2
Man, S.3
Xu, P.4
Kerbel, R.S.5
-
197
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein, B. et al. Genetic alterations during colorectal-tumor development. N. Engl. J. Med. 319, 525-532 (1988).
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
-
198
-
-
33749871965
-
The experimental study of tumor progression: A review
-
Foulds, L. The experimental study of tumor progression: a review. Cancer Res. 14, 327-339 (1954).
-
(1954)
Cancer Res.
, vol.14
, pp. 327-339
-
-
Foulds, L.1
-
199
-
-
0015421232
-
Quantitative analysis of the mechanism of glucocorticoid enhancement of experimental metastasis
-
Fidler, I. J. & Lieber, S. Quantitative analysis of the mechanism of glucocorticoid enhancement of experimental metastasis. Res. Commun. Chem. Pathol. Pharmacol. 4, 607-613 (1972).
-
(1972)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.4
, pp. 607-613
-
-
Fidler, I.J.1
Lieber, S.2
-
200
-
-
0021261333
-
Breast cancer: Relationship between the size of the primary tumour and the probability of metastatic dissemination
-
Koscielny, S. et al. Breast cancer: relationship between the size of the primary tumour and the probability of metastatic dissemination. Br. J. Cancer 49, 709-715 (1984). (Pubitemid 14113727)
-
(1984)
British Journal of Cancer
, vol.49
, Issue.6
, pp. 709-715
-
-
Koscielny, S.1
Tubiana, M.2
Le, M.G.3
-
201
-
-
0033083830
-
Impact of tumor size on the clinical outcomes of patients with Robson Stage I renal cell carcinoma
-
DOI 10.1002/(SICI)1097-0142(19990201)85:3<689::AID-CNCR19>3.0.CO;2- 7
-
Kinouchi, T. et al. Impact of tumor size on the clinical outcomes of patients with Robson State I renal cell carcinoma. Cancer 85, 689-695 (1999). (Pubitemid 29075290)
-
(1999)
Cancer
, vol.85
, Issue.3
, pp. 689-695
-
-
Kinouchi, T.1
Saiki, S.2
Meguro, N.3
Maeda, O.4
Kuroda, M.5
Usami, M.6
Kotake, T.7
-
202
-
-
77049278920
-
Observations on growth rates of human tumors
-
Collins, V. P., Loeffler, R. K. & Tivey, H. Observations on growth rates of human tumors. Am. J. Roentgenol. Radium Ther. Nucl. Med. 76, 988-1000 (1956).
-
(1956)
Am. J. Roentgenol. Radium Ther. Nucl. Med.
, vol.76
, pp. 988-1000
-
-
Collins, V.P.1
Loeffler, R.K.2
Tivey, H.3
-
203
-
-
0030872642
-
On the growth rates of human malignant tumors: Implications for medical decision making
-
DOI 10.1002/(SICI)1096-9098(199708)65:4<284::AID-JSO11>3.0.CO;2-2
-
Friberg, S. & Mattson, S. On the growth rates of human malignant tumors: implications for medical decision making. J. Surg. Oncol. 65, 284-297 (1997). (Pubitemid 27355857)
-
(1997)
Journal of Surgical Oncology
, vol.65
, Issue.4
, pp. 284-297
-
-
Friberg, S.1
Mattson, S.2
-
204
-
-
37349079197
-
Systemic Spread Is an Early Step in Breast Cancer
-
DOI 10.1016/j.ccr.2007.12.003, PII S1535610807003728
-
Husemann, Y. et al. Systemic spread is an early step in breast cancer. Cancer Cell 13, 58-68 (2008). (Pubitemid 350309740)
-
(2008)
Cancer Cell
, vol.13
, Issue.1
, pp. 58-68
-
-
Husemann, Y.1
Geigl, J.B.2
Schubert, F.3
Musiani, P.4
Meyer, M.5
Burghart, E.6
Forni, G.7
Eils, R.8
Fehm, T.9
Riethmuller, G.10
Klein, C.A.11
-
205
-
-
68949102467
-
Lower-dose vs high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: A phase 2 randomized study
-
Ellis, M. J. et al. Lower-dose vs high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: a phase 2 randomized study. JAMA 302, 774-780 (2009).
-
(2009)
JAMA
, vol.302
, pp. 774-780
-
-
Ellis, M.J.1
-
206
-
-
58249119446
-
18F-FDG PET and PET/CT in the evaluation of cancer treatment response
-
Ben-Haim, S. & Ell, P. 18F-FDG PET and PET/CT in the evaluation of cancer treatment response. J. Nucl. Med. 50, 88-99 (2009).
-
(2009)
J. Nucl. Med.
, vol.50
, pp. 88-99
-
-
Ben-Haim, S.1
Ell, P.2
-
207
-
-
63849107018
-
Novel strategy for a cocktail 18F-fluoride and 18F-FDG PET/CT scan for evaluation of malignancy: Results of the pilot-phase study
-
Iagaru, A. et al. Novel strategy for a cocktail 18F-fluoride and 18F-FDG PET/CT scan for evaluation of malignancy: results of the pilot-phase study. J. Nucl. Med. 50, 501-505 (2009).
-
(2009)
J. Nucl. Med.
, vol.50
, pp. 501-505
-
-
Iagaru, A.1
-
208
-
-
79960818838
-
Molecular imaging of tumor invasion and metastases: The role of MRI
-
12 Dec doi:10.1002/nbm.1590
-
McCann, T. E. et al. Molecular imaging of tumor invasion and metastases: the role of MRI. NMR Biomed. 12 Dec 2010 (doi:10.1002/nbm.1590).
-
(2010)
NMR Biomed.
-
-
McCann, T.E.1
-
209
-
-
70349651659
-
Melanin-targeted preclinical PET imaging of melanoma metastasis
-
Ren, G. et al. Melanin-targeted preclinical PET imaging of melanoma metastasis. J. Nucl. Med. 50, 1692-1699 (2009).
-
(2009)
J. Nucl. Med.
, vol.50
, pp. 1692-1699
-
-
Ren, G.1
-
210
-
-
0031005838
-
Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression
-
Chishima, T. et al. Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression. Cancer Res. 57, 2042-2047 (1997). (Pubitemid 27209739)
-
(1997)
Cancer Research
, vol.57
, Issue.10
, pp. 2042-2047
-
-
Chishima, T.1
Miyagi, Y.2
Wang, X.3
Yamaoka, H.4
Shimada, H.5
Moossa, A.R.6
Hoffman, R.M.7
-
211
-
-
78149262994
-
Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models
-
Liu, H. et al. Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. Proc. Natl Acad. Sci. USA 107, 18115-18120 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 18115-18120
-
-
Liu, H.1
-
212
-
-
34248156633
-
Cell tracking using a photoconvertible fluorescent protein
-
Hatta, K., Tsujii, H. & Omura, T. Cell tracking using a photoconvertible fluorescent protein. Nature Protoc. 1, 960-967 (2006).
-
(2006)
Nature Protoc.
, vol.1
, pp. 960-967
-
-
Hatta, K.1
Tsujii, H.2
Omura, T.3
-
213
-
-
80055112765
-
Dendra2 photoswitching through the Mammary Imaging Window
-
5 Jun doi:10.3791/1278
-
Gligorijevic, B., Kedrin, D., Segall, J. E., Condeelis, J. & Van Rheenen, J. Dendra2 photoswitching through the Mammary Imaging Window. J. Vis. Exp. 5 Jun 2009 (doi:10.3791/1278).
-
(2009)
J. Vis. Exp.
-
-
Gligorijevic, B.1
Kedrin, D.2
Segall, J.E.3
Condeelis, J.4
Van Rheenen, J.5
-
214
-
-
79751490911
-
Dynamic long-term in vivo imaging of tumor-stroma interactions in mouse models of breast cancer using spinning-disk confocal microscopy
-
pdb.top97 2011
-
Ewald, A. J., Werb, Z. & Egeblad, M. Dynamic, long-term in vivo imaging of tumor-stroma interactions in mouse models of breast cancer using spinning-disk confocal microscopy. Cold Spring Harb. Protoc. 2011, pdb.top97 (2011).
-
(2011)
Cold Spring Harb. Protoc.
-
-
Ewald, A.J.1
Werb, Z.2
Egeblad, M.3
-
215
-
-
77955417371
-
A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography
-
Massoud, T. F., Paulmurugan, R. & Gambhir, S. S. A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography. Nature Med. 16, 921-926 (2010).
-
(2010)
Nature Med.
, vol.16
, pp. 921-926
-
-
Massoud, T.F.1
Paulmurugan, R.2
Gambhir, S.S.3
-
216
-
-
68349160814
-
Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis
-
Korpal, M. et al. Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis. Nature Med. 15, 960-966 (2009).
-
(2009)
Nature Med.
, vol.15
, pp. 960-966
-
-
Korpal, M.1
-
217
-
-
79952419254
-
Methodological and practical challenges for personalized cancer therapies
-
Wistuba, II, Gelovani, J. G., Jacoby, J. J., Davis, S. E. & Herbst, R. S. Methodological and practical challenges for personalized cancer therapies. Nature Rev. Clin. Oncol. 8, 135-141 (2011).
-
(2011)
Nature Rev. Clin. Oncol.
, vol.8
, pp. 135-141
-
-
Wistuba, I.I.1
Gelovani, J.G.2
Jacoby, J.J.3
Davis, S.E.4
Herbst, R.S.5
-
218
-
-
69249228553
-
ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis
-
Lu, X. et al. ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. Genes Dev. 23, 1882-1894 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 1882-1894
-
-
Lu, X.1
-
219
-
-
67649311599
-
Latent bone metastasis in breast cancer tied to Src-dependent survival signals
-
Zhang, X. H. et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell 16, 67-78 (2009).
-
(2009)
Cancer Cell
, vol.16
, pp. 67-78
-
-
Zhang, X.H.1
-
220
-
-
33846049299
-
NF-κB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF
-
DOI 10.1038/nm1519, PII NM1519
-
Park, B. K. et al. NF-κB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF. Nature Med. 13, 62-69 (2007). (Pubitemid 46067387)
-
(2007)
Nature Medicine
, vol.13
, Issue.1
, pp. 62-69
-
-
Park, B.K.1
Zhang, H.2
Zeng, Q.3
Dai, J.4
Keller, E.T.5
Giordano, T.6
Gu, K.7
Shah, V.8
Pei, L.9
Zarbo, R.J.10
McCauley, L.11
Shi, S.12
Chen, S.13
Wang, C.-Y.14
-
221
-
-
34147220392
-
Mediators of vascular remodelling co-opted for sequential steps in lung metastasis
-
DOI 10.1038/nature05760, PII NATURE05760
-
Gupta, G. P. et al. Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature 446, 765-770 (2007). (Pubitemid 46582040)
-
(2007)
Nature
, vol.446
, Issue.7137
, pp. 765-770
-
-
Gupta, G.P.1
Nguyen, D.X.2
Chiang, A.C.3
Bos, P.D.4
Kim, J.Y.5
Nadal, C.6
Gomis, R.R.7
Manova-Todorova, K.8
Massague, J.9
-
222
-
-
41149157649
-
TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4
-
DOI 10.1016/j.cell.2008.01.046, PII S0092867408002110
-
Padua, D. et al. TGFβ primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell 133, 66-77 (2008). (Pubitemid 351442989)
-
(2008)
Cell
, vol.133
, Issue.1
, pp. 66-77
-
-
Padua, D.1
Zhang, X.H.-F.2
Wang, Q.3
Nadal, C.4
Gerald, W.L.5
Gomis, R.R.6
Massague, J.7
-
223
-
-
1842634484
-
Metadherin, a cell surface protein in breast tumors that mediates lung metastasis
-
DOI 10.1016/S1535-6108(04)00079-0, PII S1535610804000790
-
Brown, D. M. & Ruoslahti, E. Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. Cancer Cell 5, 365-374 (2004). (Pubitemid 38482072)
-
(2004)
Cancer Cell
, vol.5
, Issue.4
, pp. 365-374
-
-
Brown, D.M.1
Ruoslahti, E.2
-
224
-
-
37649001973
-
ID genes mediate tumor reinitiation during breast cancer lung metastasis
-
Gupta, G. P. et al. ID genes mediate tumor reinitiation during breast cancer lung metastasis. Proc. Natl Acad. Sci. USA 104, 19506-19511 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 19506-19511
-
-
Gupta, G.P.1
-
225
-
-
70449529854
-
KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer
-
Gumireddy, K. et al. KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Nature Cell Biol. 11, 1297-1304 (2009).
-
(2009)
Nature Cell Biol.
, vol.11
, pp. 1297-1304
-
-
Gumireddy, K.1
-
226
-
-
0036782035
-
MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis
-
DOI 10.1016/S1535-6108(02)00153-8
-
Hiratsuka, S. et al. MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis. Cancer Cell 2, 289-300 (2002). (Pubitemid 41043963)
-
(2002)
Cancer Cell
, vol.2
, Issue.4
, pp. 289-300
-
-
Hiratsuka, S.1
Nakamura, K.2
Iwai, S.3
Murakami, M.4
Itoh, T.5
Kijima, H.6
Shipley, J.M.7
Senior, R.M.8
Shibuya, M.9
-
227
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
DOI 10.1038/35065016
-
Muller, A. et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 410, 50-56 (2001). (Pubitemid 32225831)
-
(2001)
Nature
, vol.410
, Issue.6824
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
McClanahan, T.7
Murphy, E.8
Yuan, W.9
Wagner, S.N.10
Barrera, J.L.11
Mohar, A.12
Verastegui, E.13
Zlotnik, A.14
-
228
-
-
33645532055
-
Activation of stat3 in human melanoma promotes brain metastasis
-
Xie, T. X. et al. Activation of stat3 in human melanoma promotes brain metastasis. Cancer Res. 66, 3188-3196 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 3188-3196
-
-
Xie, T.X.1
-
229
-
-
58149352266
-
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis
-
Stein, U. et al. MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. Nature Med. 15, 59-67 (2009).
-
(2009)
Nature Med.
, vol.15
, pp. 59-67
-
-
Stein, U.1
-
230
-
-
57849100048
-
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
-
Erler, J. T. et al. Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell 15, 35-44 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 35-44
-
-
Erler, J.T.1
-
231
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
Erler, J. T. et al. Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 440, 1222-1226 (2006).
-
(2006)
Nature
, vol.440
, pp. 1222-1226
-
-
Erler, J.T.1
-
232
-
-
22244455403
-
A mouse model of human breast cancer metastasis to human bone
-
DOI 10.1158/0008-5472.CAN-04-1408
-
Kuperwasser, C. et al. A mouse model of human breast cancer metastasis to human bone. Cancer Res. 65, 6130-6138 (2005). (Pubitemid 40994398)
-
(2005)
Cancer Research
, vol.65
, Issue.14
, pp. 6130-6138
-
-
Kuperwasser, C.1
Dessain, S.2
Bierbaum, B.E.3
Garnet, D.4
Sperandio, K.5
Gauvin, G.P.6
Naber, S.P.7
Weinberg, R.A.8
Rosenblatt, M.9
-
233
-
-
0035266413
-
Establishment of a novel species- and tissue-specific metastasis model of human prostate cancer in humanized non-obese diabetic/severe combined immunodeficient mice engrafted with human adult lung and bone
-
Yonou, H. et al. Establishment of a novel species-and tissue-specific metastasis model of human prostate cancer in humanized non-obese diabetic/severe combined immunodeficient mice engrafted with human adult lung and bone. Cancer Res. 61, 2177-2182 (2001). (Pubitemid 32692044)
-
(2001)
Cancer Research
, vol.61
, Issue.5
, pp. 2177-2182
-
-
Yonou, H.1
Yokose, T.2
Kamijo, T.3
Kanomata, N.4
Hasebe, T.5
Nagai, K.6
Hatano, T.7
Ogawa, Y.8
Ochiai, A.9
-
234
-
-
0033561535
-
Severe combined immunodeficient-hu model of human prostate cancer metastasis to human bone
-
Nemeth, J. A. et al. Severe combined immunodeficient-hu model of human prostate cancer metastasis to human bone. Cancer Res. 59, 1987-1993 (1999). (Pubitemid 29186176)
-
(1999)
Cancer Research
, vol.59
, Issue.8
, pp. 1987-1993
-
-
Nemeth, J.A.1
Harb, J.F.2
Barroso Jr., U.3
He, Z.4
Grignon, D.J.5
Cher, M.L.6
-
235
-
-
0029076829
-
Species-specific metastasis of human tumor cells in the severe combined immunodeficiency mouse engrafted with human tissue
-
Shtivelman, E. & Namikawa, R. Species-specific metastasis of human tumor cells in the severe combined immunodeficiency mouse engrafted with human tissue. Proc. Natl Acad. Sci. USA 92, 4661-4665 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 4661-4665
-
-
Shtivelman, E.1
Namikawa, R.2
-
236
-
-
0028240519
-
Identification of transformation sensitive proteins recorded in human two- dimensional gel protein databases by mass spectrometric peptide mapping alone and in combination with microsequencing
-
Rasmussen, H. H., Mortz, E., Mann, M., Roepstorff, P. & Celis, J. E. Identification of transformation sensitive proteins recorded in human two-dimensional gel protein databases by mass spectrometric peptide mapping alone and in combination with microsequencing. Electrophoresis 15, 406-416 (1994). (Pubitemid 24151841)
-
(1994)
Electrophoresis
, vol.15
, Issue.3-4
, pp. 406-416
-
-
Rasmussen, H.H.1
Mortz, E.2
Mann, M.3
Roepstorff, P.4
Celis, J.E.5
-
237
-
-
0031719058
-
Multiphoton excitation provides optical sections from deeper within scattering specimens than confocal imaging
-
Centonze, V. E. & White, J. G. Multiphoton excitation provides optical sections from deeper within scattering specimens than confocal imaging. Biophys. J. 75, 2015-2024 (1998). (Pubitemid 28455197)
-
(1998)
Biophysical Journal
, vol.75
, Issue.4
, pp. 2015-2024
-
-
Centonze, V.E.1
White, J.G.2
-
238
-
-
0029780689
-
Multiphoton fluorescence excitation: New spectral windows for biological nonlinear microscopy
-
DOI 10.1073/pnas.93.20.10763
-
Xu, C., Zipfel, W., Shear, J. B., Williams, R. M. & Webb, W. W. Multiphoton fluorescence excitation: new spectral windows for biological nonlinear microscopy. Proc. Natl Acad. Sci. USA 93, 10763-10768 (1996). (Pubitemid 26333063)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.20
, pp. 10763-10768
-
-
Xu, C.1
Zipfel, W.2
Shear, J.B.3
Williams, R.M.4
Webb, W.W.5
-
239
-
-
0033055607
-
Video microscopy of tumor metastasis: Using the green fluorescent protein (GFP) gene as a cancer-cell-labeling system
-
Kan, Z. & Liu, T. J. Video microscopy of tumor metastasis: using the green fluorescent protein (GFP) gene as a cancer-cell-labeling system. Clin. Exp. Metastasis 17, 49-55 (1999). (Pubitemid 29284564)
-
(1999)
Clinical and Experimental Metastasis
, vol.17
, Issue.1
, pp. 49-55
-
-
Kan, Z.1
Liu, T.-J.2
-
240
-
-
0030809607
-
Intravital videomicroscopic evidence for regulation of metastasis by the hepatic microvasculature: Effects of interleukin-1α on metastasis and the location of B16F1 melanoma cell arrest
-
Scherbarth, S. & Orr, F. W. Intravital videomicroscopic evidence for regulation of metastasis by the hepatic microvasculature: effects of interleukin-1α on metastasis and the location of B16F1 melanoma cell arrest. Cancer Res. 57, 4105-4110 (1997). (Pubitemid 27427704)
-
(1997)
Cancer Research
, vol.57
, Issue.18
, pp. 4105-4110
-
-
Scherbarth, S.1
Orr, F.W.2
-
241
-
-
0029562902
-
Steps in tumor metastasis: New concepts from intravital videomicroscopy
-
DOI 10.1007/BF00690599
-
Chambers, A. F. et al. Steps in tumor metastasis: new concepts from intravital videomicroscopy. Cancer Metastasis Rev. 14, 279-301 (1995). (Pubitemid 26027931)
-
(1995)
Cancer and Metastasis Reviews
, vol.14
, Issue.4
, pp. 279-301
-
-
Chambers, A.F.1
MacDonald, I.C.2
Schmidt, E.E.3
Koop, S.4
Morris, V.L.5
Khokha, R.6
Groom, A.C.7
-
242
-
-
0031787596
-
Detection of brain tumor invasion and micrometastasis in vivo by expression of enhanced green fluorescent protein
-
MacDonald, T. J., Tabrizi, P., Shimada, H., Zlokovic, B. V. & Laug, W. E. Detection of brain tumor invasion and micrometastasis in vivo by expression of enhanced green fluorescent protein. Neurosurgery 43, 1437-1443 (1998). (Pubitemid 28545875)
-
(1998)
Neurosurgery
, vol.43
, Issue.6
, pp. 1437-1443
-
-
MacDonald, T.J.1
Tabrizi, P.2
Shimada, H.3
Zlokovic, B.V.4
Laug, W.E.5
-
243
-
-
0032526151
-
Cell motility of tumor cells visualized in living intact primary tumors using green fluorescent protein
-
Farina, K. L. et al. Cell motility of tumor cells visualized in living intact primary tumors using green fluorescent protein. Cancer Res. 58, 2528-2532 (1998). (Pubitemid 28275420)
-
(1998)
Cancer Research
, vol.58
, Issue.12
, pp. 2528-2532
-
-
Farina, K.L.1
Wyckoff, J.B.2
Rivera, J.3
Lee, H.4
Segall, J.E.5
Condeelis, J.S.6
Jones, J.G.7
-
244
-
-
0031822837
-
Tissue microarrays for high-throughput molecular profiling of tumor specimens
-
DOI 10.1038/nm0798-844
-
Kononen, J. et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nature Med. 4, 844-847 (1998). (Pubitemid 28331029)
-
(1998)
Nature Medicine
, vol.4
, Issue.7
, pp. 844-847
-
-
Kononen, J.1
Bubendorf, L.2
Kallioniemi, A.3
Barlund, M.4
Schraml, P.5
Leighton, S.6
Torhorst, J.7
Mihatsch, M.J.8
Sauter, G.9
Kallioniemi, O.-P.10
-
245
-
-
0032418507
-
Monoclonal antibody approved for metastatic breast cancer
-
Monoclonal antibody approved for metastatic breast cancer. Oncology 12, 1727 (1998).
-
(1998)
Oncology
, vol.12
, pp. 1727
-
-
-
246
-
-
0034704248
-
Genome-wide location and function of DNA binding proteins
-
DOI 10.1126/science.290.5500.2306
-
Ren, B. et al. Genome-wide location and function of DNA binding proteins. Science 290, 2306-2309 (2000). (Pubitemid 32041573)
-
(2000)
Science
, vol.290
, Issue.5500
, pp. 2306-2309
-
-
Ren, B.1
Robert, F.2
Wyrick, J.J.3
Aparicio, O.4
Jennings, E.G.5
Simon, I.6
Zeitlinger, J.7
Schreiber, J.8
Hannett, N.9
Kanin, E.10
Volkert, T.L.11
Wilson, C.J.12
Bell, S.P.13
Young, R.A.14
-
247
-
-
0033597717
-
Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region
-
DOI 10.1016/S0092-8674(00)81019-3
-
Blat, Y. & Kleckner, N. Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region. Cell 98, 249-259 (1999). (Pubitemid 29344912)
-
(1999)
Cell
, vol.98
, Issue.2
, pp. 249-259
-
-
Blat, Y.1
Kleckner, N.2
-
248
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
DOI 10.1038/35102167
-
Reya, T., Morrison, S. J., Clarke, M. F. & Weissman, I. L. Stem cells, cancer, and cancer stem cells. Nature 414, 105-111 (2001). (Pubitemid 33041634)
-
(2001)
Nature
, vol.414
, Issue.6859
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
249
-
-
0034598746
-
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
-
DOI 10.1038/35000501
-
Alizadeh, A. A. et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403, 503-511 (2000). (Pubitemid 30082188)
-
(2000)
Nature
, vol.403
, Issue.6769
, pp. 503-511
-
-
Alizadeh, A.A.1
Elsen, M.B.2
Davis, R.E.3
Ma, Ch.L.4
Lossos, I.S.5
Rosenwald, A.6
Boldrick, J.C.7
Sabet, H.8
Tran, T.9
Yu, X.10
Powell, J.I.11
Yang, L.12
Maru, G.E.13
Moore, T.14
Hudson Jr., J.15
Lu, L.16
Lewis, D.B.17
Tibshirani, R.18
Sherlock, G.19
Chan, W.C.20
Greiner, T.C.21
Weisenburger, D.D.22
Armitage, J.O.23
Warnke, R.24
Levy, R.25
Wilson, W.26
Grever, M.R.27
Byrd, J.C.28
Botstein, D.29
Brown, P.O.30
Staudt, L.M.31
more..
-
250
-
-
0035970039
-
Expression profiling reveals fundamental biological differences in acute myeloid leukemia with isolated trisomy 8 and normal cytogenetics
-
DOI 10.1073/pnas.98.3.1124
-
Virtaneva, K. et al. Expression profiling reveals fundamental biological differences in acute myeloid leukemia with isolated trisomy 8 and normal cytogenetics. Proc. Natl Acad. Sci. USA 98, 1124-1129 (2001). (Pubitemid 32121197)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.3
, pp. 1124-1129
-
-
Virtaneva, K.1
Wright, F.A.2
Tanner, S.M.3
Yuan, B.4
Lemon, W.J.5
Caligiuri, M.A.6
Bloomfield, C.D.7
De La Chapelle, A.8
Krahe, R.9
-
251
-
-
0035848705
-
Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front
-
Paweletz, C. P. et al. Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front. Oncogene 20, 1981-1989 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 1981-1989
-
-
Paweletz, C.P.1
-
252
-
-
0037226593
-
A molecular signature of metastasis in primary solid tumors
-
DOI 10.1038/ng1060
-
Ramaswamy, S., Ross, K. N., Lander, E. S. & Golub, T. R. A molecular signature of metastasis in primary solid tumors. Nature Genet. 33, 49-54 (2003). (Pubitemid 36068681)
-
(2003)
Nature Genetics
, vol.33
, Issue.1
, pp. 49-54
-
-
Ramaswamy, S.1
Ross, K.N.2
Lander, E.S.3
Golub, T.R.4
-
253
-
-
0036828286
-
Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling
-
Wang, W. et al. Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling. Cancer Res. 62, 6278-6288 (2002). (Pubitemid 35244482)
-
(2002)
Cancer Research
, vol.62
, Issue.21
, pp. 6278-6288
-
-
Wang, W.1
Wyckoff, J.B.2
Frohlich, V.C.3
Oleynikov, Y.4
Huttelmaier, S.5
Zavadil, J.6
Cermak, L.7
Bottinger, E.P.8
Singer, R.H.9
White, J.G.10
Segall, J.E.11
Condeelis, J.S.12
-
254
-
-
24044455869
-
Genome sequencing in microfabricated high-density picolitre reactors
-
DOI 10.1038/nature03959, PII N03959
-
Margulies, M. et al. Genome sequencing in microfabricated high-density picolitre reactors. Nature 437, 376-380 (2005). (Pubitemid 41613494)
-
(2005)
Nature
, vol.437
, Issue.7057
, pp. 376-380
-
-
Margulies, M.1
Egholm, M.2
Altman, W.E.3
Attiya, S.4
Bader, J.S.5
Bemben, L.A.6
Berka, J.7
Braverman, M.S.8
Chen, Y.-J.9
Chen, Z.10
Dewell, S.B.11
Du, L.12
Fierro, J.M.13
Gomes, X.V.14
Godwin, B.C.15
He, W.16
Helgesen, S.17
Ho, C.H.18
Irzyk, G.P.19
Jando, S.C.20
Alenquer, M.L.I.21
Jarvie, T.P.22
Jirage, K.B.23
Kim, J.-B.24
Knight, J.R.25
Lanza, J.R.26
Leamon, J.H.27
Lefkowitz, S.M.28
Lei, M.29
Li, J.30
Lohman, K.L.31
Lu, H.32
Makhijani, V.B.33
McDade, K.E.34
McKenna, M.P.35
Myers, E.W.36
Nickerson, E.37
Nobile, J.R.38
Plant, R.39
Puc, B.P.40
Ronan, M.T.41
Roth, G.T.42
Sarkis, G.J.43
Simons, J.F.44
Simpson, J.W.45
Srinivasan, M.46
Tartaro, K.R.47
Tomasz, A.48
Vogt, K.A.49
Volkmer, G.A.50
Wang, S.H.51
Wang, Y.52
Weiner, M.P.53
Yu, P.54
Begley, R.F.55
Rothberg, J.M.56
more..
-
255
-
-
24644462173
-
Molecular biology: Accurate multiplex polony sequencing of an evolved bacterial genome
-
DOI 10.1126/science.1117389
-
Shendure, J. et al. Accurate multiplex polony sequencing of an evolved bacterial genome. Science 309, 1728-1732 (2005). (Pubitemid 41285943)
-
(2005)
Science
, vol.309
, Issue.5741
, pp. 1728-1732
-
-
Shendure, J.1
Porreca, G.J.2
Reppas, N.B.3
Lin, X.4
McCutcheon, J.P.5
Rosenbaum, A.M.6
Wang, M.D.7
Zhang, K.8
Mitra, R.D.9
Church, G.M.10
-
256
-
-
33645813378
-
Mass spectrometry and protein analysis
-
Domon, B. & Aebersold, R. Mass spectrometry and protein analysis. Science 312, 212-217 (2006).
-
(2006)
Science
, vol.312
, pp. 212-217
-
-
Domon, B.1
Aebersold, R.2
-
257
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
DOI 10.1016/j.cell.2007.05.009, PII S0092867407006009
-
Barski, A. et al. High-resolution profiling of histone methylations in the human genome. Cell 129, 823-837 (2007). (Pubitemid 46802390)
-
(2007)
Cell
, vol.129
, Issue.4
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.-Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
258
-
-
45549088326
-
The transcriptional landscape of the yeast genome defined by RNA sequencing
-
DOI 10.1126/science.1158441
-
Nagalakshmi, U. et al. The transcriptional landscape of the yeast genome defined by RNA sequencing. Science 320, 1344-1349 (2008). (Pubitemid 351929471)
-
(2008)
Science
, vol.320
, Issue.5881
, pp. 1344-1349
-
-
Nagalakshmi, U.1
Wang, Z.2
Waern, K.3
Shou, C.4
Raha, D.5
Gerstein, M.6
Snyder, M.7
-
259
-
-
46249096804
-
Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution
-
DOI 10.1038/nature07002, PII NATURE07002
-
Wilhelm, B. T. et al. Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution. Nature 453, 1239-1243 (2008). (Pubitemid 351913597)
-
(2008)
Nature
, vol.453
, Issue.7199
, pp. 1239-1243
-
-
Wilhelm, B.T.1
Marguerat, S.2
Watt, S.3
Schubert, F.4
Wood, V.5
Goodhead, I.6
Penkett, C.J.7
Rogers, J.8
Bahler, J.9
-
260
-
-
46249106990
-
Mapping and quantifying mammalian transcriptomes by RNA-Seq
-
DOI 10.1038/nmeth.1226, PII NMETH.1226
-
Mortazavi, A., Williams, B. A., McCue, K., Schaeffer, L. & Wold, B. Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nature Methods 5, 621-628 (2008). (Pubitemid 351911867)
-
(2008)
Nature Methods
, vol.5
, Issue.7
, pp. 621-628
-
-
Mortazavi, A.1
Williams, B.A.2
McCue, K.3
Schaeffer, L.4
Wold, B.5
-
261
-
-
42749087226
-
Highly integrated single-base resolution maps of the epigenome in Arabidopsis
-
Lister, R. et al. Highly integrated single-base resolution maps of the epigenome in Arabidopsis. Cell 133, 523-536 (2008).
-
(2008)
Cell
, vol.133
, pp. 523-536
-
-
Lister, R.1
-
262
-
-
46249103973
-
Stem cell transcriptome profiling via massive-scale mRNA sequencing
-
DOI 10.1038/nmeth.1223, PII NMETH.1223
-
Cloonan, N. et al. Stem cell transcriptome profiling via massive-scale mRNA sequencing. Nature Methods 5, 613-619 (2008). (Pubitemid 351911866)
-
(2008)
Nature Methods
, vol.5
, Issue.7
, pp. 613-619
-
-
Cloonan, N.1
Forrest, A.R.R.2
Kolle, G.3
Gardiner, B.B.A.4
Faulkner, G.J.5
Brown, M.K.6
Taylor, D.F.7
Steptoe, A.L.8
Wani, S.9
Bethel, G.10
Robertson, A.J.11
Perkins, A.C.12
Bruce, S.J.13
Lee, C.C.14
Ranade, S.S.15
Peckham, H.E.16
Manning, J.M.17
McKernan, K.J.18
Grimmond, S.M.19
-
263
-
-
50649089207
-
RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays
-
Marioni, J. C., Mason, C. E., Mane, S. M., Stephens, M. & Gilad, Y. RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays. Genome Res. 18, 1509-1517 (2008).
-
(2008)
Genome Res.
, vol.18
, pp. 1509-1517
-
-
Marioni, J.C.1
Mason, C.E.2
Mane, S.M.3
Stephens, M.4
Gilad, Y.5
-
264
-
-
77953006634
-
The mutation spectrum revealed by paired genome sequences from a lung cancer patient
-
Lee, W. et al. The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature 465, 473-477 (2010).
-
(2010)
Nature
, vol.465
, pp. 473-477
-
-
Lee, W.1
-
265
-
-
55549101623
-
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
-
Ley, T. J. et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 456, 66-72 (2008).
-
(2008)
Nature
, vol.456
, pp. 66-72
-
-
Ley, T.J.1
-
266
-
-
70149093912
-
Recurring mutations found by sequencing an acute myeloid leukemia genome
-
Mardis, E. R. et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N. Engl. J. Med. 361, 1058-1066 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1058-1066
-
-
Mardis, E.R.1
-
267
-
-
70349969478
-
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
-
Shah, S. P. et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature 461, 809-813 (2009).
-
(2009)
Nature
, vol.461
, pp. 809-813
-
-
Shah, S.P.1
-
268
-
-
74449093973
-
A comprehensive catalogue of somatic mutations from a human cancer genome
-
Pleasance, E. D. et al. A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 463, 191-196 (2010).
-
(2010)
Nature
, vol.463
, pp. 191-196
-
-
Pleasance, E.D.1
-
269
-
-
79959774035
-
Denosumab an option for patients with bone metastasis from breast cancer
-
Barton, M. K. Denosumab an option for patients with bone metastasis from breast cancer. CA Cancer J. Clin. 61, 135-136 (2011).
-
(2011)
CA Cancer J. Clin.
, vol.61
, pp. 135-136
-
-
Barton, M.K.1
-
270
-
-
78650397541
-
Clinical development of anti-RANKL therapies for treatment and prevention of bone metastasis
-
Lipton, A. & Goessl, C. Clinical development of anti-RANKL therapies for treatment and prevention of bone metastasis. Bone 48, 96-99 (2011).
-
(2011)
Bone
, vol.48
, pp. 96-99
-
-
Lipton, A.1
Goessl, C.2
-
271
-
-
77957941316
-
BRAF inhibitor unveils its potential against advanced melanoma
-
Vultur, A., Villanueva, J. & Herlyn, M. BRAF inhibitor unveils its potential against advanced melanoma. Cancer Cell 18, 301-302 (2010).
-
(2010)
Cancer Cell
, vol.18
, pp. 301-302
-
-
Vultur, A.1
Villanueva, J.2
Herlyn, M.3
-
272
-
-
78649727505
-
Inhibition of mutated BRAF in melanoma
-
Kim, T., Kim, J. & Lee, M. G. Inhibition of mutated BRAF in melanoma. N. Engl. J. Med. 363, 2261 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 2261
-
-
Kim, T.1
Kim, J.2
Lee, M.G.3
|