Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells

Matrix Biology

Volumn 27, Issue 6, 2008, Pages 573-585

  Serebriiskii, Ilya ^a   Castelló Cros, Remedios ^a   Lamb, Acacia ^a   Golemis, Erica A ^a   Cukierman, Edna ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

1 integrin; Cancer cell; Drug response; Extracellular matrix; Fibroblast; Microenvironment; Taxol; Three dimensional matrix; Tumor stroma

Indexed keywords

BETA1 INTEGRIN; FOCAL ADHESION KINASE 1; GEFITINIB; IMATINIB; MONOCYTE CHEMOTACTIC PROTEIN 1; PACLITAXEL; PROTEIN KINASE B; SORAFENIB;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL PROLIFERATION; CELL STRAIN HCT116; CELL STRAIN MCF 7; CELL SURVIVAL; CONTROLLED STUDY; DRUG RESPONSE; DRUG SCREENING; EPITHELIUM CELL; EXTRACELLULAR MATRIX; FIBROBLAST; FIBROBLAST DERIVED THREE DIMENSIONAL MATRIX; GROWTH REGULATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD29; ANTINEOPLASTIC AGENTS; CELL CULTURE TECHNIQUES; DRUG SCREENING ASSAYS, ANTITUMOR; FIBROBLASTS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; MATERIALS TESTING; MICE; NF-KAPPA B; NIH 3T3 CELLS; PROTO-ONCOGENE PROTEINS C-AKT; TISSUE SCAFFOLDS; TUMOR CELLS, CULTURED;

EID: 48149105146     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.matbio.2008.02.008     Document Type: Article

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