Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells

Biomaterials

Volumn 31, Issue 32, 2010, Pages 8494-8506

  Loessner, Daniela ^a   Stok, Kathryn S ^b   Lutolf, Matthias P ^c   Hutmacher, Dietmar W ^a   Clements, Judith A ^a   Rizzi, Simone C ^a  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^b ETH ZURICH   (Switzerland)

^c EPFL   (Switzerland)

Author keywords

Biomimetic material; Cell encapsulation; Cell morphology; Cell viability; ECM; Hydrogel

Indexed keywords

3-D CULTURE SYSTEM; 3D CULTURE; ANTICANCER DRUG; BIOMIMETIC HYDROGELS; CANCER CELLS; CANCER RESEARCH; CELL ENCAPSULATION; CELL LINES; CELL MATRIX INTERACTIONS; CELL MODEL; CELL MONOLAYERS; CELL MORPHOLOGY; CELL VIABILITY; CHEMORESISTANCE; CHEMOSENSITIVITY; CULTURE SYSTEMS; DESIGN FLEXIBILITY; DRUG RESISTANCE; ECM; EXTRACELLULAR; HYDROGEL MATRIX; IN-CELL; IN-VIVO; INTEGRIN-BINDING MOTIFS; INTEGRINS; LONG-TERM CULTURE; MATRIX; METALLOPROTEASES; MICROENVIRONMENTS; OVARIAN CANCER CELLS; OVARIAN CANCERS; PACLITAXEL; PATHOPHYSIOLOGICAL; RGD PEPTIDE; SCIENTIFIC TOOL; SURVIVAL RATE; THREE DIMENSIONAL (3D) STRUCTURES;

BIOMIMETIC MATERIALS; BIOMIMETICS; CELLS; DRUG INTERACTIONS; ENZYME ACTIVITY; HYDROGELS; MONOLAYERS; MORPHOLOGY; THREE DIMENSIONAL;

CELL CULTURE;

BIOMIMETIC MATERIAL; INTEGRIN; PACLITAXEL;

ARTICLE; BIOENGINEERING; CANCER CELL; CARCINOGENESIS; CELL CULTURE; CELL INTERACTION; CELL PROLIFERATION; CHEMOSENSITIVITY; EPITHELIUM CELL; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HYDROGEL; MICROENVIRONMENT; OVARY CANCER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN MOTIF; PROTEOMICS; REPRODUCIBILITY; SURVIVAL RATE; THREE DIMENSION CULTURE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOENGINEERING; BIOMIMETIC MATERIALS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; EPITHELIAL CELLS; FEMALE; HUMANS; HYDROGEL; INTEGRINS; MECHANICAL PHENOMENA; OLIGOPEPTIDES; OVARIAN NEOPLASMS; PACLITAXEL; POLYETHYLENE GLYCOLS; SPHEROIDS, CELLULAR;

EID: 77956187576     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.07.064     Document Type: Article

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