메뉴 건너뛰기




Volumn 24, Issue 6, 2013, Pages 751-765

Transformation of the Fallopian Tube Secretory Epithelium Leads to High-Grade Serous Ovarian Cancer in Brca;Tp53;Pten Models

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53;

EID: 84891937100     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2013.10.013     Document Type: Article
Times cited : (433)

References (55)
  • 2
    • 84864026311 scopus 로고    scopus 로고
    • BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group
    • Alsop K., Fereday S., Meldrum C., deFazio A., Emmanuel C., George J., Dobrovic A., Birrer M.J., Webb P.M., Stewart C., et al. BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group. J.Clin. Oncol. 2012, 30:2654-2663.
    • (2012) J.Clin. Oncol. , vol.30 , pp. 2654-2663
    • Alsop, K.1    Fereday, S.2    Meldrum, C.3    deFazio, A.4    Emmanuel, C.5    George, J.6    Dobrovic, A.7    Birrer, M.J.8    Webb, P.M.9    Stewart, C.10
  • 3
    • 0347625462 scopus 로고    scopus 로고
    • Status of tumor markers in ovarian cancer screening
    • Bast R.C. Status of tumor markers in ovarian cancer screening. J.Clin. Oncol. 2003, 21(10 Suppl):200s-205s.
    • (2003) J.Clin. Oncol. , vol.21 , Issue.10 SUPPL
    • Bast, R.C.1
  • 4
    • 84875648021 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase and INPP4B in human breast cancer
    • Bertucci M.C., Mitchell C.A. Phosphoinositide 3-kinase and INPP4B in human breast cancer. Ann. N Y Acad. Sci. 2013, 1280:1-5.
    • (2013) Ann. N Y Acad. Sci. , vol.1280 , pp. 1-5
    • Bertucci, M.C.1    Mitchell, C.A.2
  • 6
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Research Network
    • Integrated genomic analyses of ovarian carcinoma. Nature 2011, 474:609-615. Cancer Genome Atlas Research Network.
    • (2011) Nature , vol.474 , pp. 609-615
  • 10
    • 33845644738 scopus 로고    scopus 로고
    • Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes
    • Clark-Knowles K.V., Garson K., Jonkers J., Vanderhyden B.C. Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes. Exp. Cell Res. 2007, 313:133-145.
    • (2007) Exp. Cell Res. , vol.313 , pp. 133-145
    • Clark-Knowles, K.V.1    Garson, K.2    Jonkers, J.3    Vanderhyden, B.C.4
  • 11
    • 77954057957 scopus 로고    scopus 로고
    • Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas
    • Clark-Knowles K.V., Senterman M.K., Collins O., Vanderhyden B.C. Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas. PLoS ONE 2009, 4:e8534.
    • (2009) PLoS ONE , vol.4
    • Clark-Knowles, K.V.1    Senterman, M.K.2    Collins, O.3    Vanderhyden, B.C.4
  • 13
    • 13444269246 scopus 로고    scopus 로고
    • Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer
    • Dinulescu D.M., Ince T.A., Quade B.J., Shafer S.A., Crowley D., Jacks T. Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer. Nat. Med. 2005, 11:63-70.
    • (2005) Nat. Med. , vol.11 , pp. 63-70
    • Dinulescu, D.M.1    Ince, T.A.2    Quade, B.J.3    Shafer, S.A.4    Crowley, D.5    Jacks, T.6
  • 14
    • 84859727275 scopus 로고    scopus 로고
    • The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse
    • Database issue, Mouse Genome Database Group
    • Eppig J.T., Blake J.A., Bult C.J., Kadin J.A., Richardson J.E. The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse. Nucleic Acids Res. 2012, 40(Database issue):D881-D886. Mouse Genome Database Group.
    • (2012) Nucleic Acids Res. , vol.40
    • Eppig, J.T.1    Blake, J.A.2    Bult, C.J.3    Kadin, J.A.4    Richardson, J.E.5
  • 16
    • 0038756581 scopus 로고    scopus 로고
    • Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium
    • Flesken-Nikitin A., Choi K.C., Eng J.P., Shmidt E.N., Nikitin A.Y. Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium. Cancer Res. 2003, 63:3459-3463.
    • (2003) Cancer Res. , vol.63 , pp. 3459-3463
    • Flesken-Nikitin, A.1    Choi, K.C.2    Eng, J.P.3    Shmidt, E.N.4    Nikitin, A.Y.5
  • 21
    • 80054795415 scopus 로고    scopus 로고
    • Molecular requirements for transformation of fallopian tube epithelial cells into serous carcinoma
    • Jazaeri A.A., Bryant J.L., Park H., Li H., Dahiya N., Stoler M.H., Ferriss J.S., Dutta A. Molecular requirements for transformation of fallopian tube epithelial cells into serous carcinoma. Neoplasia 2011, 13:899-911.
    • (2011) Neoplasia , vol.13 , pp. 899-911
    • Jazaeri, A.A.1    Bryant, J.L.2    Park, H.3    Li, H.4    Dahiya, N.5    Stoler, M.H.6    Ferriss, J.S.7    Dutta, A.8
  • 22
    • 0035734285 scopus 로고    scopus 로고
    • Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
    • Jonkers J., Meuwissen R., van der Gulden H., Peterse H., van der Valk M., Berns A. Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat. Genet. 2001, 29:418-425.
    • (2001) Nat. Genet. , vol.29 , pp. 418-425
    • Jonkers, J.1    Meuwissen, R.2    van der Gulden, H.3    Peterse, H.4    van der Valk, M.5    Berns, A.6
  • 23
    • 79956313481 scopus 로고    scopus 로고
    • Modeling high-grade serous ovarian carcinogenesis from the fallopian tube
    • Karst A.M., Levanon K., Drapkin R. Modeling high-grade serous ovarian carcinogenesis from the fallopian tube. Proc. Natl. Acad. Sci. USA 2011, 108:7547-7552.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 7547-7552
    • Karst, A.M.1    Levanon, K.2    Drapkin, R.3
  • 24
    • 80052576079 scopus 로고    scopus 로고
    • Stathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas
    • Karst A.M., Levanon K., Duraisamy S., Liu J.F., Hirsch M.S., Hecht J.L., Drapkin R. Stathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas. Gynecol. Oncol. 2011, 123:5-12.
    • (2011) Gynecol. Oncol. , vol.123 , pp. 5-12
    • Karst, A.M.1    Levanon, K.2    Duraisamy, S.3    Liu, J.F.4    Hirsch, M.S.5    Hecht, J.L.6    Drapkin, R.7
  • 28
    • 79961032045 scopus 로고    scopus 로고
    • Telomere length in different histologic types of ovarian carcinoma with emphasis on clear cell carcinoma
    • Kuhn E., Meeker A.K., Visvanathan K., Gross A.L., Wang T.L., Kurman R.J., Shih IeM. Telomere length in different histologic types of ovarian carcinoma with emphasis on clear cell carcinoma. Mod. Pathol. 2011, 24:1139-1145.
    • (2011) Mod. Pathol. , vol.24 , pp. 1139-1145
    • Kuhn, E.1    Meeker, A.K.2    Visvanathan, K.3    Gross, A.L.4    Wang, T.L.5    Kurman, R.J.6    Shih, I.7
  • 32
    • 0036928961 scopus 로고    scopus 로고
    • Pathologic findings in prophylactic oophorectomy specimens in high-risk women
    • Leeper K., Garcia R., Swisher E., Goff B., Greer B., Paley P. Pathologic findings in prophylactic oophorectomy specimens in high-risk women. Gynecol. Oncol. 2002, 87:52-56.
    • (2002) Gynecol. Oncol. , vol.87 , pp. 52-56
    • Leeper, K.1    Garcia, R.2    Swisher, E.3    Goff, B.4    Greer, B.5    Paley, P.6
  • 33
  • 34
    • 55949089955 scopus 로고    scopus 로고
    • New insights into the pathogenesis of serous ovarian cancer and its clinical impact
    • Levanon K., Crum C., Drapkin R. New insights into the pathogenesis of serous ovarian cancer and its clinical impact. J.Clin. Oncol. 2008, 26:5284-5293.
    • (2008) J.Clin. Oncol. , vol.26 , pp. 5284-5293
    • Levanon, K.1    Crum, C.2    Drapkin, R.3
  • 36
    • 33846421673 scopus 로고    scopus 로고
    • Congenital hypothyroid female pax8-deficient mice are infertile despite thyroid hormone replacement therapy
    • Mittag J., Winterhager E., Bauer K., Grümmer R. Congenital hypothyroid female pax8-deficient mice are infertile despite thyroid hormone replacement therapy. Endocrinology 2007, 148:719-725.
    • (2007) Endocrinology , vol.148 , pp. 719-725
    • Mittag, J.1    Winterhager, E.2    Bauer, K.3    Grümmer, R.4
  • 37
    • 80051790678 scopus 로고    scopus 로고
    • Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model invivo
    • Mullany L.K., Fan H.Y., Liu Z., White L.D., Marshall A., Gunaratne P., Anderson M.L., Creighton C.J., Xin L., Deavers M., et al. Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model invivo. Oncogene 2011, 30:3522-3536.
    • (2011) Oncogene , vol.30 , pp. 3522-3536
    • Mullany, L.K.1    Fan, H.Y.2    Liu, Z.3    White, L.D.4    Marshall, A.5    Gunaratne, P.6    Anderson, M.L.7    Creighton, C.J.8    Xin, L.9    Deavers, M.10
  • 41
    • 0036677403 scopus 로고    scopus 로고
    • Early restriction of peripheral and proximal cell lineages during formation of the lung
    • Perl A.K., Wert S.E., Nagy A., Lobe C.G., Whitsett J.A. Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc. Natl. Acad. Sci. USA 2002, 99:10482-10487.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 10482-10487
    • Perl, A.K.1    Wert, S.E.2    Nagy, A.3    Lobe, C.G.4    Whitsett, J.A.5
  • 47
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 1999, 21:70-71.
    • (1999) Nat. Genet. , vol.21 , pp. 70-71
    • Soriano, P.1
  • 49
    • 79959310044 scopus 로고    scopus 로고
    • Expression of PAX8 in normal and neoplastic tissues: a comprehensive immunohistochemical study
    • Tacha D., Zhou D., Cheng L. Expression of PAX8 in normal and neoplastic tissues: a comprehensive immunohistochemical study. Appl. Immunohistochem. Mol. Morphol. 2011, 19:293-299.
    • (2011) Appl. Immunohistochem. Mol. Morphol. , vol.19 , pp. 293-299
    • Tacha, D.1    Zhou, D.2    Cheng, L.3
  • 52
    • 78751629661 scopus 로고    scopus 로고
    • BRCA1 CpG island hypermethylation predicts sensitivity to poly(adenosine diphosphate)-ribose polymerase inhibitors
    • author reply e565-566
    • Veeck J., Ropero S., Setien F., Gonzalez-Suarez E., Osorio A., Benitez J., Herman J.G., Esteller M. BRCA1 CpG island hypermethylation predicts sensitivity to poly(adenosine diphosphate)-ribose polymerase inhibitors. J Clin Oncol 2010, 28:e563-564. author reply e565-566.
    • (2010) J Clin Oncol , vol.28
    • Veeck, J.1    Ropero, S.2    Setien, F.3    Gonzalez-Suarez, E.4    Osorio, A.5    Benitez, J.6    Herman, J.G.7    Esteller, M.8
  • 53
    • 34047171574 scopus 로고    scopus 로고
    • Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways
    • Wu R., Hendrix-Lucas N., Kuick R., Zhai Y., Schwartz D.R., Akyol A., Hanash S., Misek D.E., Katabuchi H., Williams B.O., et al. Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways. Cancer Cell 2007, 11:321-333.
    • (2007) Cancer Cell , vol.11 , pp. 321-333
    • Wu, R.1    Hendrix-Lucas, N.2    Kuick, R.3    Zhai, Y.4    Schwartz, D.R.5    Akyol, A.6    Hanash, S.7    Misek, D.E.8    Katabuchi, H.9    Williams, B.O.10
  • 54
    • 84875205987 scopus 로고    scopus 로고
    • Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer
    • Wu R., Baker S.J., Hu T.C., Norman K.M., Fearon E.R., Cho K.R. Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer. Am. J. Pathol. 2013, 182:1391-1399.
    • (2013) Am. J. Pathol. , vol.182 , pp. 1391-1399
    • Wu, R.1    Baker, S.J.2    Hu, T.C.3    Norman, K.M.4    Fearon, E.R.5    Cho, K.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.