Translation of a tumor microenvironment mimicking 3D tumor growth co-culture assay platform to high-content screening

Journal of Biomolecular Screening

Volumn 18, Issue 1, 2013, Pages 54-66

  Krausz, Eberhard ^a   De Hoogt, Ronald ^a   Gustin, Emmanuel ^a   Cornelissen, Frans ^a   Grand Perret, Thierry ^a   Janssen, Lut ^a   Vloemans, Nele ^a   Wuyts, Dirk ^a   Frans, Sandy ^a   Axel, Amy ^a   Peeters, Pieter Johan ^a   Hall, Brett ^a   Cik, Miroslav ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

3D cell culture; assay development; high content screening; tumor microenvironment

Indexed keywords

4 (8 CYCLOPENTYL 7 ETHYL 5,6,7,8 TETRAHYDRO 5 METHYL 6 OXO 2 PTERIDINYLAMINO) 3 METHOXY N (1 METHYL 4 PIPERIDINYL)BENZAMIDE; ANTINEOPLASTIC AGENT; BMS 303141; CAMPTOTHECIN; N (2,3 DIHYDROXYPROPOXY) 3,4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO)BENZAMIDE; SARACATINIB; TANDUTINIB; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; DRUG SCREENING; EPIFLUORESCENCE MICROSCOPY; HUMAN; IMAGE ANALYSIS; IN VITRO STUDY; MESENCHYMAL STEM CELL; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR VOLUME;

ANTINEOPLASTIC AGENTS; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; COCULTURE TECHNIQUES; DRUG SCREENING ASSAYS, ANTITUMOR; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INHIBITORY CONCENTRATION 50; MESENCHYMAL STROMAL CELLS; REFERENCE STANDARDS; SOFTWARE; TUMOR MICROENVIRONMENT;

EID: 84871574173     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057112456874     Document Type: Article

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