Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 8, Issue 5, 2012, Pages 757-766

  Sharma, Shivani ^a   Santiskulvong, Chintda ^a   Bentolila, Laurent A ^a   Rao, JianYu ^b   Dorigo, Oliver ^a   Gimzewski, James K ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTE FOR MATERIALS SCIENCE   (Japan)

Author keywords

Actin remodeling; Cisplatin resistance; Nanomechanics; Ovarian cancer; Stimulated emission depletion (STED)

Indexed keywords

ACTIN REMODELING; CANCER BIOLOGY; CANCER DRUG; CELL STIFFNESS; CHEMOTHERAPEUTIC AGENTS; CIS-PLATIN; CISPLATIN-RESISTANT CELL; DOSE-DEPENDENT; DRUG RESISTANCE; F-ACTIN; FUTURE APPLICATIONS; MOLECULAR LEVELS; MOLECULAR MECHANISM; NANOSCALE LEVELS; OVARIAN CANCER CELLS; OVARIAN CANCERS; RESISTANT CELLS; STIMULATED EMISSION DEPLETION; SUPER RESOLUTION; SUPER-RESOLUTION MICROSCOPY;

ATOMIC FORCE MICROSCOPY; BIOMECHANICS; CELLS; DISEASES; NANOMECHANICS; OPTICAL RESOLVING POWER; PLATINUM; PLATINUM COMPOUNDS; STIFFNESS;

PROTEINS;

CISPLATIN; F ACTIN;

ACTIN POLYMERIZATION; ARTICLE; BIOMECHANICS; CANCER CELL; CYTOSKELETON; DRUG RESISTANCE; DRUG SENSITIVITY; FEMALE; HUMAN; HUMAN CELL; MICROSCOPY; MOLECULAR MECHANICS; OVARY CANCER; STIMULATED EMISSION DEPLETION MICROSCOPY; YOUNG MODULUS;

ACTIN CYTOSKELETON; ACTINS; CELL LINE, TUMOR; CISPLATIN; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; MICROSCOPY, ATOMIC FORCE; OVARIAN NEOPLASMS; POLYMERIZATION;

EID: 84862688660     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2011.09.015     Document Type: Article

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