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Volumn 93, Issue 5, 2013, Pages 528-542

A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro

Author keywords

cell adhesion; chemoresistance; chemoresponse; epithelial ovarian cancer; microenvironment; three dimensional modeling

Indexed keywords

BIOLOGICAL MARKER; CISPLATIN; CYTOSKELETON PROTEIN; PACLITAXEL; PLASTIC; POLYHYDROXOETHYLAMETHACRYLATE; UNCLASSIFIED DRUG;

EID: 84877255483     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2013.41     Document Type: Article
Times cited : (257)

References (65)
  • 1
    • 39249085679 scopus 로고    scopus 로고
    • Opportunities and challenges in ovarian cancer research, a perspective from the 11th Ovarian Cancer Action/HHMT Forum, Lake Como, March, 2007
    • Ashworth A, Balkwill F, Bast RC, et al. Opportunities and challenges in ovarian cancer research, a perspective from the 11th Ovarian Cancer Action/HHMT Forum, Lake Como, March 2007. Gynecol Oncol 2008;108:652-657.
    • (2008) Gynecol Oncol , vol.108 , pp. 652-657
    • Ashworth, A.1    Balkwill, F.2    Bast, R.C.3
  • 2
    • 79956003662 scopus 로고    scopus 로고
    • Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma
    • Ma XH, Piao S, Wang D, et al. Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma. Clin Cancer Res 2011;17:3478-3489.
    • (2011) Clin Cancer Res , vol.17 , pp. 3478-3489
    • Ma, X.H.1    Piao, S.2    Wang, D.3
  • 3
    • 33745075558 scopus 로고    scopus 로고
    • Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases
    • Smalley KS, Haass NK, Brafford PA, et al. Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases. Mol Cancer Ther 2006;5:1136-1144.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1136-1144
    • Smalley, K.S.1    Haass, N.K.2    Brafford, P.A.3
  • 4
    • 0036206915 scopus 로고    scopus 로고
    • Distinctive alterations of invasiveness, drug resistance and cell-cell organization in 3D-cultures of MCF-7, a human breast cancer cell line, and its multidrug resistant variant
    • dit Faute MA, Laurent L, Ploton D, et al. Distinctive alterations of invasiveness, drug resistance and cell-cell organization in 3D-cultures of MCF-7, a human breast cancer cell line, and its multidrug resistant variant. Clin Exp Metastasis 2002;19:161-168.
    • (2002) Clin Exp Metastasis , vol.19 , pp. 161-168
    • Dit Faute, M.A.1    Laurent, L.2    Ploton, D.3
  • 5
    • 77953540958 scopus 로고    scopus 로고
    • HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment
    • Weigelt B, Lo AT, Park CC, et al. HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment. Breast Cancer Res Treat 2010;122:35-43.
    • (2010) Breast Cancer Res Treat , vol.122 , pp. 35-43
    • Weigelt, B.1    Lo, A.T.2    Park, C.C.3
  • 6
    • 0024505367 scopus 로고
    • Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane
    • Barcellos-Hoff MH, Aggeler J, Ram TG, et al. Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. Development 1989;105:223-235.
    • (1989) Development , vol.105 , pp. 223-235
    • Barcellos-Hoff, M.H.1    Aggeler, J.2    Ram, T.G.3
  • 7
    • 0024366450 scopus 로고
    • A new high-yield continuous cell-culture system for lymphokine-activated killer cells
    • Tokuda Y, Nakamura Y, Suzuki A, et al. A new high-yield continuous cell-culture system for lymphokine-activated killer cells. Cancer Immunol Immunother 1989;30:1-4.
    • (1989) Cancer Immunol Immunother , vol.30 , pp. 1-4
    • Tokuda, Y.1    Nakamura, Y.2    Suzuki, A.3
  • 8
    • 0032734016 scopus 로고    scopus 로고
    • Induction of threedimensional assembly of human liver cells by simulated microgravity
    • Khaoustov VI, Darlington GJ, Soriano HE, et al. Induction of threedimensional assembly of human liver cells by simulated microgravity. In Vitro Cell Dev Biol Anim 1999;35:501-509.
    • (1999) Vitro Cell Dev Biol Anim , vol.35 , pp. 501-509
    • Khaoustov, V.I.1    Darlington, G.J.2    Soriano, H.E.3
  • 9
    • 65349087874 scopus 로고    scopus 로고
    • In vitro three-dimensional modelling of human ovarian surface epithelial cells
    • Lawrenson K, Benjamin E, Turmaine M, et al. In vitro three-dimensional modelling of human ovarian surface epithelial cells. Cell Prolif 2009;42:385-393.
    • (2009) Cell Prolif , vol.42 , pp. 385-393
    • Lawrenson, K.1    Benjamin, E.2    Turmaine, M.3
  • 10
    • 0035054981 scopus 로고    scopus 로고
    • Scaffold design and fabrication technologies for engineering tissues-state of the art and future perspectives
    • Hutmacher DW. Scaffold design and fabrication technologies for engineering tissues-state of the art and future perspectives. J Biomater Sci Polym Ed 2001;12:107-124.
    • (2001) J Biomater Sci Polym Ed , vol.12 , pp. 107-124
    • Hutmacher, D.W.1
  • 11
    • 21644487903 scopus 로고    scopus 로고
    • Three-dimensional culture of melanoma cells profoundly affects gene expression profile: A high density oligonucleotide array study
    • Ghosh S, Spagnoli GC, Martin I, et al. Three-dimensional culture of melanoma cells profoundly affects gene expression profile: a high density oligonucleotide array study. J Cell Physiol 2005;204: 522-531.
    • (2005) J Cell Physiol , vol.204 , pp. 522-531
    • Ghosh, S.1    Spagnoli, G.C.2    Martin, I.3
  • 12
    • 14444274090 scopus 로고    scopus 로고
    • Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix
    • Gómez-Lechón MJ, Jover R, Donato T, et al. Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix. J Cell Physiol 1998;177:553-562.
    • (1998) J Cell Physiol , vol.177 , pp. 553-562
    • Gómez-Lechón, M.J.1    Jover, R.2    Donato, T.3
  • 13
    • 0028863558 scopus 로고
    • Control of integrin expression by extracellular matrix
    • Delcommenne M, Streuli CH. Control of integrin expression by extracellular matrix. J Biol Chem 1995;270:26794-26801.
    • (1995) J Biol Chem , vol.270 , pp. 26794-26801
    • Delcommenne, M.1    Streuli, C.H.2
  • 14
    • 34248650697 scopus 로고    scopus 로고
    • The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression
    • Kenny PA, Lee GY, Myers CA, et al. The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression. Mol Oncol 2007;1:84-96.
    • (2007) Mol Oncol , vol.1 , pp. 84-96
    • Kenny, P.A.1    Lee, G.Y.2    Myers, C.A.3
  • 15
    • 79958191830 scopus 로고    scopus 로고
    • Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
    • Rohwer N, Cramer T. Hypoxia-mediated drug resistance: novel insights on the functional interaction of HIFs and cell death pathways. Drug Resist Update 2011;14:191-201.
    • (2011) Drug Resist Update , vol.14 , pp. 191-201
    • Rohwer, N.1    Cramer, T.2
  • 16
    • 84858723379 scopus 로고    scopus 로고
    • Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation
    • Vinci M, Gowan S, Boxall F, et al. Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation. BMC Biol 2012;10:29.
    • (2012) BMC Biol , vol.10 , pp. 29
    • Vinci, M.1    Gowan, S.2    Boxall, F.3
  • 17
    • 60549103259 scopus 로고    scopus 로고
    • Spheroid-based drug screen: Considerations and practical approach
    • Friedrich J, Seidel C, Ebner R, et al. Spheroid-based drug screen: considerations and practical approach. Nat Protoc 2009;4:309-324.
    • (2009) Nat Protoc , vol.4 , pp. 309-324
    • Friedrich, J.1    Seidel, C.2    Ebner, R.3
  • 18
    • 77955039099 scopus 로고    scopus 로고
    • Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: A proof-of-concept trial
    • Audeh MW, Carmichael J, Penson RT, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet 2010;376:245-251.
    • (2010) Lancet , vol.376 , pp. 245-251
    • Audeh, M.W.1    Carmichael, J.2    Penson, R.T.3
  • 19
    • 43449107359 scopus 로고    scopus 로고
    • A multi-institutional evaluation of factors predictive of toxicity and efficacy of bevacizumab for recurrent ovarian cancer
    • Wright JD, Secord AA, Numnum TM, et al. A multi-institutional evaluation of factors predictive of toxicity and efficacy of bevacizumab for recurrent ovarian cancer. Int J Gynecol Cancer 2008;18:400-406.
    • (2008) Int J Gynecol Cancer , vol.18 , pp. 400-406
    • Wright, J.D.1    Secord, A.A.2    Numnum, T.M.3
  • 20
    • 0043240182 scopus 로고    scopus 로고
    • Ovarian cancer: Strategies for overcoming resistance to chemotherapy
    • Agarwal R, Kaye SB. Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 2003;3:502-516.
    • (2003) Nat Rev Cancer , vol.3 , pp. 502-516
    • Agarwal, R.1    Kaye, S.B.2
  • 21
    • 0020055650 scopus 로고
    • Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells
    • Eva A, Robbins KC, Andersen PR, et al. Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells. Nature 1982;295:116-119.
    • (1982) Nature , vol.295 , pp. 116-119
    • Eva, A.1    Robbins, K.C.2    Andersen, P.R.3
  • 22
    • 0026594392 scopus 로고
    • High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis
    • Godwin AK, Meister A, O'Dwyer PJ, et al. High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis. Proc Natl Acad Sci USA 1992;89:3070-3074.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3070-3074
    • Godwin, A.K.1    Meister, A.2    O'Dwyer, P.J.3
  • 23
    • 0021815179 scopus 로고
    • Radiation survival parameters of antineoplastic drug-sensitive and-resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine
    • Louie KG, Behrens BC, Kinsella TJ, et al. Radiation survival parameters of antineoplastic drug-sensitive and-resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine. Cancer Res 1985;45:2110-2115.
    • (1985) Cancer Res , vol.45 , pp. 2110-2115
    • Louie, K.G.1    Behrens, B.C.2    Kinsella, T.J.3
  • 24
    • 0021933379 scopus 로고
    • Comparative properties of five human ovarian adenocarcinoma cell lines
    • Buick RN, Pullano R, Trent JM, et al. Comparative properties of five human ovarian adenocarcinoma cell lines. Cancer Res 1985;45: 3668-3676.
    • (1985) Cancer Res , vol.45 , pp. 3668-3676
    • Buick, R.N.1    Pullano, R.2    Trent, J.M.3
  • 25
    • 0027532010 scopus 로고
    • Establishment and characterization of 7 ovarian carcinoma cell lines and one granulosa tumor cell line: Growth features and cytogenetics
    • van den Berg-Bakker CA, Hagemeijer A, Franken-Postma EM, et al. Establishment and characterization of 7 ovarian carcinoma cell lines and one granulosa tumor cell line: growth features and cytogenetics. Int J Cancer 1993;53:613-620.
    • (1993) Int J Cancer , vol.53 , pp. 613-620
    • Van Den Berg-Bakker, C.A.1    Hagemeijer, A.2    Franken-Postma, E.M.3
  • 26
    • 0020527061 scopus 로고
    • Cell lines derived from human ovarian carcinomas: Growth stimulation by gonadotropic and steroid hormones
    • Simon WE, Albrecht M, Hänsel M, et al. Cell lines derived from human ovarian carcinomas: growth stimulation by gonadotropic and steroid hormones. J Natl Cancer Inst 1983;70:839-845.
    • (1983) J Natl Cancer Inst , vol.70 , pp. 839-845
    • Simon, W.E.1    Albrecht, M.2    Hänsel, M.3
  • 27
    • 0025949649 scopus 로고
    • Multifactorial mechanisms associated with broad cross-resistance of ovarian carcinoma cells selected by cyanomorpholino doxorubicin
    • Lau DH, Lewis AD, Ehsan MN, et al. Multifactorial mechanisms associated with broad cross-resistance of ovarian carcinoma cells selected by cyanomorpholino doxorubicin. Cancer Res 1991;51: 5181-5187.
    • (1991) Cancer Res , vol.51 , pp. 5181-5187
    • Lau, D.H.1    Lewis, A.D.2    Ehsan, M.N.3
  • 28
    • 0025011698 scopus 로고
    • Ascitic fluid from human ovarian cancer patients contains growth factors necessary for intraperitoneal growth of human ovarian adenocarcinoma cells
    • Mills GB, May C, Hill M, et al. Ascitic fluid from human ovarian cancer patients contains growth factors necessary for intraperitoneal growth of human ovarian adenocarcinoma cells. J Clin Invest 1990;86: 851-855.
    • (1990) J Clin Invest , vol.86 , pp. 851-855
    • Mills, G.B.1    May, C.2    Hill, M.3
  • 29
    • 0022409597 scopus 로고
    • Characterization of a human ovarian adenocarcinoma line, IGROV1, in tissue culture and in nude mice
    • Bénard J, Da Silva J, De Blois MC, et al. Characterization of a human ovarian adenocarcinoma line, IGROV1, in tissue culture and in nude mice. Cancer Res 1985;45:4970-4979.
    • (1985) Cancer Res , vol.45 , pp. 4970-4979
    • Bénard, J.1    Da Silva, J.2    De Blois, M.C.3
  • 30
    • 0023180865 scopus 로고
    • Intraperitoneal xenografts of human epithelial ovarian cancer in nude mice
    • Ward BG, Wallace K, Shepherd JH, et al. Intraperitoneal xenografts of human epithelial ovarian cancer in nude mice. Cancer Res 1987;47:2662-2667.
    • (1987) Cancer Res , vol.47 , pp. 2662-2667
    • Ward, B.G.1    Wallace, K.2    Shepherd, J.H.3
  • 31
    • 0025816320 scopus 로고
    • The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines
    • Mistry P, Kelland LR, Abel G, et al. The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines. Br J Cancer 1991;64:215-220.
    • (1991) Br J Cancer , vol.64 , pp. 215-220
    • Mistry, P.1    Kelland, L.R.2    Abel, G.3
  • 32
    • 0021368773 scopus 로고
    • Characterization of a cell line derived from the ascites of a patient with papillary serous cystadenocarcinoma of the ovary
    • Wilson AP. Characterization of a cell line derived from the ascites of a patient with papillary serous cystadenocarcinoma of the ovary. J Natl Cancer Inst 1984;72:513-521.
    • (1984) J Natl Cancer Inst , vol.72 , pp. 513-521
    • Wilson, A.P.1
  • 33
    • 0030200810 scopus 로고    scopus 로고
    • Establishment and characterization of three new cell lines derived from the ascites of human ovarian carcinomas
    • Alama A, Barbieri F, Favre A, et al. Establishment and characterization of three new cell lines derived from the ascites of human ovarian carcinomas. Gynecol Oncol 1996;62:82-88.
    • (1996) Gynecol Oncol , vol.62 , pp. 82-88
    • Alama, A.1    Barbieri, F.2    Favre, A.3
  • 34
    • 0015455019 scopus 로고
    • Cell-mediated immunity to human malignant cells. A brief review and further studies with two gynecologic tumors
    • DiSaia PJ, Sinkovics JG, Rutledge FN, et al. Cell-mediated immunity to human malignant cells. A brief review and further studies with two gynecologic tumors. Am J Obstet Gynecol 1972;114:979-989.
    • (1972) Am J Obstet Gynecol , vol.114 , pp. 979-989
    • Disaia, P.J.1    Sinkovics, J.G.2    Rutledge, F.N.3
  • 35
    • 0026752490 scopus 로고
    • Mitochondrial defects in cisdiamminedichloroplatinum( II)-resistant human ovarian carcinoma cells
    • Andrews PA, Albright KD. Mitochondrial defects in cisdiamminedichloroplatinum( II)-resistant human ovarian carcinoma cells. Cancer Res 1992;52:1895-1901.
    • (1992) Cancer Res , vol.52 , pp. 1895-1901
    • Andrews, P.A.1    Albright, K.D.2
  • 36
    • 0019790278 scopus 로고
    • Reactivity of a monoclonal antibody with human ovarian carcinoma
    • Bast Jr RC, Feeney M, Lazarus H, et al. Reactivity of a monoclonal antibody with human ovarian carcinoma. J Clin Invest 1981;68: 1331-1337.
    • (1981) J Clin Invest , vol.68 , pp. 1331-1337
    • Bast Jr., R.C.1    Feeney, M.2    Lazarus, H.3
  • 37
    • 0021058774 scopus 로고
    • Characterization of a human ovarian carcinoma cell line (NIH:OVAR-3) with androgen and estrogen receptors
    • Hamilton TC, Young RC, McKoy WM, et al. Characterization of a human ovarian carcinoma cell line (NIH:OVAR-3) with androgen and estrogen receptors. Cancer Res 1983;43:5379-5389.
    • (1983) Cancer Res , vol.43 , pp. 5379-5389
    • Hamilton, T.C.1    Young, R.C.2    McKoy, W.M.3
  • 38
    • 0024836776 scopus 로고
    • Mechanisms of resistance to cisplatin and alkylating agents
    • Hamilton TC, Lai GM, Rothenberg ML, et al. Mechanisms of resistance to cisplatin and alkylating agents. Cancer Treat Res 1989;48:151-169.
    • (1989) Cancer Treat Res , vol.48 , pp. 151-169
    • Hamilton, T.C.1    Lai, G.M.2    Rothenberg, M.L.3
  • 39
    • 0028267296 scopus 로고
    • Establishment of new ovarian and colon carcinoma cell lines: Differentiation is only possible by cytokeratin analysis
    • Mö bus VJ, Moll R, Gerharz CD, et al. Establishment of new ovarian and colon carcinoma cell lines: differentiation is only possible by cytokeratin analysis. Br J Cancer 1994;69:422-428.
    • (1994) Br J Cancer , vol.69 , pp. 422-428
    • Mö Bus, V.J.1    Moll, R.2    Gerharz, C.D.3
  • 40
    • 0024563482 scopus 로고
    • Biological properties of ten human ovarian carcinoma cell lines: Calibration in vitro against four platinum complexes
    • Hills CA, Kelland LR, Abel G, et al. Biological properties of ten human ovarian carcinoma cell lines: calibration in vitro against four platinum complexes. Br J Cancer 1989;59:527-534.
    • (1989) Br J Cancer , vol.59 , pp. 527-534
    • Hills, C.A.1    Kelland, L.R.2    Abel, G.3
  • 41
    • 0027409399 scopus 로고
    • Enhances c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A
    • Yu D, Wolf JK, Scanlon M, et al. Enhances c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A. Cancer Res 1993;53: 891-898.
    • (1993) Cancer Res , vol.53 , pp. 891-898
    • Yu, D.1    Wolf, J.K.2    Scanlon, M.3
  • 42
    • 0033869716 scopus 로고    scopus 로고
    • Characterization of four novel epithelial ovarian cancer cell lines
    • Provencher DM, Lounis H, Champoux L, et al. Characterization of four novel epithelial ovarian cancer cell lines. In Vitro Cell Dev Biol Anim 2000;36:357-361.
    • (2000) Vitro Cell Dev Biol Anim , vol.36 , pp. 357-361
    • Provencher, D.M.1    Lounis, H.2    Champoux, L.3
  • 43
    • 33846976549 scopus 로고    scopus 로고
    • Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation
    • DelloRusso C, Welcsh PL, Wang W, et al. Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation. Mol Cancer Res 2007;5:35-45.
    • (2007) Mol Cancer Res , vol.5 , pp. 35-45
    • Dellorusso, C.1    Welcsh, P.L.2    Wang, W.3
  • 44
    • 0024383676 scopus 로고
    • DNA flow cytometry, clinical and morphological parameters as prognostic factors for advanced malignant and borderline ovarian tumors
    • Kühn W, Kaufmann M, Feichter GE, et al. DNA flow cytometry, clinical and morphological parameters as prognostic factors for advanced malignant and borderline ovarian tumors. Gynecol Oncol 1989;33:360-367.
    • (1989) Gynecol Oncol , vol.33 , pp. 360-367
    • Kühn, W.1    Kaufmann, M.2    Feichter, G.E.3
  • 45
    • 10344219949 scopus 로고    scopus 로고
    • Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer
    • Shaw TJ, Senterman MK, Dawson K, et al. Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer. Mol Ther 2004;10:1032-1042.
    • (2004) Mol Ther , vol.10 , pp. 1032-1042
    • Shaw, T.J.1    Senterman, M.K.2    Dawson, K.3
  • 46
    • 84865694064 scopus 로고    scopus 로고
    • DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination
    • Korch C, Spillman MA, Jackson TA, et al. DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination. Gynecol Oncol 2012;127: 241-248.
    • (2012) Gynecol Oncol , vol.127 , pp. 241-248
    • Korch, C.1    Spillman, M.A.2    Jackson, T.A.3
  • 47
    • 6944238451 scopus 로고    scopus 로고
    • Prognostic value of E-cadherin immunoexpression in patients with primary ovarian carcinomas
    • Faleiro-Rodrigues C, Macedo-Pinto I, Pereira D, et al. Prognostic value of E-cadherin immunoexpression in patients with primary ovarian carcinomas. Ann Oncol 2004;15:1535-1542.
    • (2004) Ann Oncol , vol.15 , pp. 1535-1542
    • Faleiro-Rodrigues, C.1    MacEdo-Pinto, I.2    Pereira, D.3
  • 48
    • 0031889636 scopus 로고    scopus 로고
    • Expression of E-cadherin, alphacatenin and beta-catenin in normal ovarian surface epithelium and epithelial ovarian cancers
    • Davies BR, Worsley SD, Ponder BA. Expression of E-cadherin, alphacatenin and beta-catenin in normal ovarian surface epithelium and epithelial ovarian cancers. Histopathology 1998;32:69-80.
    • (1998) Histopathology , vol.32 , pp. 69-80
    • Davies, B.R.1    Worsley, S.D.2    Ponder, B.A.3
  • 49
    • 58149489177 scopus 로고    scopus 로고
    • Ovarian carcinoma subtypes are different diseases: Implications for biomarker studies
    • Köbel M, Kalloger SE, Boyd N, et al. Ovarian carcinoma subtypes are different diseases: implications for biomarker studies. PLoS Med 2008;5:e232.
    • (2008) PLoS Med , vol.5
    • Köbel, M.1    Kalloger, S.E.2    Boyd, N.3
  • 50
    • 35148854943 scopus 로고    scopus 로고
    • Molecular description of a 3D in vitro model for the study of epithelial ovarian cancer (EOC)
    • Zietarska M, Maugard CM, Filali-Mouhim A, et al. Molecular description of a 3D in vitro model for the study of epithelial ovarian cancer (EOC). Mol Carcinog 2007;46:872-885.
    • (2007) Mol Carcinog , vol.46 , pp. 872-885
    • Zietarska, M.1    Maugard, C.M.2    Filali-Mouhim, A.3
  • 51
    • 67650097016 scopus 로고    scopus 로고
    • Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion
    • Barbolina MV, Adley BP, Kelly DL, et al. Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion. Int J Cancer 2009;125:816-825.
    • (2009) Int J Cancer , vol.125 , pp. 816-825
    • Barbolina, M.V.1    Adley, B.P.2    Kelly, D.L.3
  • 52
    • 63449105639 scopus 로고    scopus 로고
    • Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype
    • Sodek KL, Ringuette MJ, Brown TJ. Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype. Int J Cancer 2009;124:2060-2070.
    • (2009) Int J Cancer , vol.124 , pp. 2060-2070
    • Sodek, K.L.1    Ringuette, M.J.2    Brown, T.J.3
  • 53
    • 34548274060 scopus 로고    scopus 로고
    • Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum
    • Kenny HA, Krausz T, Yamada SD, et al. Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum. Int J Cancer 2007;121:1463-1472.
    • (2007) Int J Cancer , vol.121 , pp. 1463-1472
    • Kenny, H.A.1    Krausz, T.2    Yamada, S.D.3
  • 54
    • 80053169555 scopus 로고    scopus 로고
    • Ovarian cancer spheroids use myosin-generated force to clear the mesothelium
    • Iwanicki MP, Davidowitz RA, Ng MR, et al. Ovarian cancer spheroids use myosin-generated force to clear the mesothelium. Cancer Discov 2011;1:144-157.
    • (2011) Cancer Discov , vol.1 , pp. 144-157
    • Iwanicki, M.P.1    Davidowitz, R.A.2    Ng, M.R.3
  • 55
    • 77953381842 scopus 로고    scopus 로고
    • Constitutive activation of BMP signalling abrogates experimental metastasis of OVCA429 cells via reduced cell adhesion
    • Shepherd TG, Mujoomdar ML, Nachtigal MW. Constitutive activation of BMP signalling abrogates experimental metastasis of OVCA429 cells via reduced cell adhesion. J Ovarian Res 2010;3:5.
    • (2010) J Ovarian Res , vol.3 , pp. 5
    • Shepherd, T.G.1    Mujoomdar, M.L.2    Nachtigal, M.W.3
  • 56
    • 79955417842 scopus 로고    scopus 로고
    • Differential expressions of adhesive molecules and proteases define mechanisms of ovarian tumor cell matrix penetration/invasion
    • Kwon Y, Cukierman E, Godwin AK. Differential expressions of adhesive molecules and proteases define mechanisms of ovarian tumor cell matrix penetration/invasion. PLoS One 2011;6:e18872.
    • (2011) PLoS One , vol.6
    • Kwon, Y.1    Cukierman, E.2    Godwin, A.K.3
  • 57
    • 0038627534 scopus 로고    scopus 로고
    • Cell-cell adhesion in the normal ovary and ovarian tumors of epithelial origin; An exception to the rule
    • Sundfeldt K. Cell-cell adhesion in the normal ovary and ovarian tumors of epithelial origin; an exception to the rule. Mol Cell Endocrinol 2003;202:89-96.
    • (2003) Mol Cell Endocrinol , vol.202 , pp. 89-96
    • Sundfeldt, K.1
  • 58
    • 0030801438 scopus 로고    scopus 로고
    • E-cadherin expression in human epithelial ovarian cancer and normal ovary
    • Sundfeldt K, Piontkewitz Y, Ivarsson K, et al. E-cadherin expression in human epithelial ovarian cancer and normal ovary. Int J Cancer 1997;74:275-280.
    • (1997) Int J Cancer , vol.74 , pp. 275-280
    • Sundfeldt, K.1    Piontkewitz, Y.2    Ivarsson, K.3
  • 59
    • 0023917563 scopus 로고
    • Common epithelial ovarian tumors. Immunohistochemical intermediate filament profiles
    • Dabbs DJ, Geisinger KR. Common epithelial ovarian tumors. Immunohistochemical intermediate filament profiles. Cancer 1988;62:368-374.
    • (1988) Cancer , vol.62 , pp. 368-374
    • Dabbs, D.J.1    Geisinger, K.R.2
  • 60
    • 0032895235 scopus 로고    scopus 로고
    • Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer
    • Goldenberg MM. Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer. Clin Ther 1999;21:309-318.
    • (1999) Clin Ther , vol.21 , pp. 309-318
    • Goldenberg, M.M.1
  • 61
    • 79959529448 scopus 로고    scopus 로고
    • A 3D model of ovarian cancer cell lines on peptide nanofiber scaffold to explore the cell-scaffold interaction and chemotherapeutic resistance of anticancer drugs
    • Yang Z, Zhao X. A 3D model of ovarian cancer cell lines on peptide nanofiber scaffold to explore the cell-scaffold interaction and chemotherapeutic resistance of anticancer drugs. Int J Nanomedicine 2011;6:303-310.
    • (2011) Int J Nanomedicine , vol.6 , pp. 303-310
    • Yang, Z.1    Zhao, X.2
  • 62
    • 78549253203 scopus 로고    scopus 로고
    • Synergistic enhancement of carboplatin efficacy with photodynamic therapy in a three-dimensional model for micrometastatic ovarian cancer
    • Rizvi I, Celli JP, Evans CL, et al. Synergistic enhancement of carboplatin efficacy with photodynamic therapy in a three-dimensional model for micrometastatic ovarian cancer. Cancer Res 2010;70: 9319-9328.
    • (2010) Cancer Res , vol.70 , pp. 9319-9328
    • Rizvi, I.1    Celli, J.P.2    Evans, C.L.3
  • 63
    • 78549244847 scopus 로고    scopus 로고
    • Ki-67 as a molecular target for therapy in an in vitro three-dimensional model for ovarian cancer
    • Rahmanzadeh R, Rai P, Celli JP, et al. Ki-67 as a molecular target for therapy in an in vitro three-dimensional model for ovarian cancer. Cancer Res 2010;70:9234-9242.
    • (2010) Cancer Res , vol.70 , pp. 9234-9242
    • Rahmanzadeh, R.1    Rai, P.2    Celli, J.P.3
  • 64
    • 80051839527 scopus 로고    scopus 로고
    • Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT
    • Evans CL, Abu-Yousif AO, Park YJ, et al. Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT. PLoS One 2011;6:e23434.
    • (2011) PLoS One , vol.6
    • Evans, C.L.1    Abu-Yousif, A.O.2    Park, Y.J.3
  • 65
    • 77956187576 scopus 로고    scopus 로고
    • Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells
    • Loessner D, Stok KS, Lutolf MP, et al. Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells. Biomaterials 2010;31:8494-8506.
    • (2010) Biomaterials , vol.31 , pp. 8494-8506
    • Loessner, D.1    Stok, K.S.2    Lutolf, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.