-
1
-
-
45549109634
-
Metastatic patterns of cancers: Results from a large autopsy study
-
Disibio, G. & French, S.W. Metastatic patterns of cancers: results from a large autopsy study. Arch. Pathol. Lab. Med. 132, 931-939 (2008).
-
(2008)
Arch. Pathol. Lab. Med.
, vol.132
, pp. 931-939
-
-
Disibio, G.1
French, S.W.2
-
2
-
-
49249119901
-
Transmission of glioblastoma multiforme after bilateral lung transplantation
-
Chen, H., Shah, A.S., Girgis, R.E. & Grossman, S.A. Transmission of glioblastoma multiforme after bilateral lung transplantation. J. Clin. Oncol. 26, 3284-3285 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 3284-3285
-
-
Chen, H.1
Shah, A.S.2
Girgis, R.E.3
Grossman, S.A.4
-
3
-
-
44849114353
-
Subtypes of breast cancer show preferential site of relapse
-
Smid, M. et al. Subtypes of breast cancer show preferential site of relapse. Cancer Res. 68, 3108-3114 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 3108-3114
-
-
Smid, M.1
-
4
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou, C.M. et al. Molecular portraits of human breast tumours. Nature 406, 747-752 (2000).
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
-
5
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
van de Vijver, M.J. et al. A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med. 347, 1999-2009 (2002).
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 1999-2009
-
-
Van De Vijver, M.J.1
-
6
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sørlie, T. et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl. Acad. Sci. USA 98, 10869-10874 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10869-10874
-
-
Sørlie, T.1
-
7
-
-
84874645057
-
Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity
-
Wang, Z.A. et al. Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity. Nat. Cell Biol. 15, 274-283 (2013).
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 274-283
-
-
Wang, Z.A.1
-
8
-
-
68349130357
-
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
-
Lim, E. et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat. Med. 15, 907-913 (2009).
-
(2009)
Nat. Med.
, vol.15
, pp. 907-913
-
-
Lim, E.1
-
9
-
-
77956218241
-
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
-
Molyneux, G. et al. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell 7, 403-417 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 403-417
-
-
Molyneux, G.1
-
10
-
-
33644844519
-
Host genetics influence tumour metastasis
-
Hunter, K. Host genetics influence tumour metastasis. Nat. Rev. Cancer 6, 141-146 (2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 141-146
-
-
Hunter, K.1
-
11
-
-
84863664841
-
Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis
-
Winter, S.F., Lukes, L., Walker, R.C., Welch, D.R. & Hunter, K.W. Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis. PLoS Genet. 8, e1002735 (2012).
-
(2012)
PLoS Genet.
, vol.8
-
-
Winter, S.F.1
Lukes, L.2
Walker, R.C.3
Welch, D.R.4
Hunter, K.W.5
-
12
-
-
84876912041
-
Inherited variation in miR-290 expression suppresses breast cancer progression by targeting the metastasis susceptibility gene Arid4b
-
Goldberger, N., Walker, R.C., Kim, C.H., Winter, S. & Hunter, K.W. Inherited variation in miR-290 expression suppresses breast cancer progression by targeting the metastasis susceptibility gene Arid4b. Cancer Res. 73, 2671-2681 (2013).
-
(2013)
Cancer Res.
, vol.73
, pp. 2671-2681
-
-
Goldberger, N.1
Walker, R.C.2
Kim, C.H.3
Winter, S.4
Hunter, K.W.5
-
13
-
-
84866949705
-
Cadm1 is a metastasis susceptibility gene that suppresses metastasis by modifying tumor interaction with the cell-mediated immunity
-
Faraji, F. et al. Cadm1 is a metastasis susceptibility gene that suppresses metastasis by modifying tumor interaction with the cell-mediated immunity. PLoS Genet. 8, e1002926 (2012).
-
(2012)
PLoS Genet.
, vol.8
-
-
Faraji, F.1
-
14
-
-
84875490185
-
Cancer genome landscapes
-
Vogelstein, B. et al. Cancer genome landscapes. Science 339, 1546-1558 (2013).
-
(2013)
Science
, vol.339
, pp. 1546-1558
-
-
Vogelstein, B.1
-
15
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon, D.J. et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N. Engl. J. Med. 344, 783-792 (2001).
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
-
16
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman, P.B. et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N. Engl. J. Med. 364, 2507-2516 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
-
17
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak, E.L. et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N. Engl. J. Med. 363, 1693-1703 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
-
18
-
-
84874857331
-
HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: Implications for efficacy of adjuvant trastuzumab
-
Ithimakin, S. et al. HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: implications for efficacy of adjuvant trastuzumab. Cancer Res. 73, 1635-1646 (2013).
-
(2013)
Cancer Res.
, vol.73
, pp. 1635-1646
-
-
Ithimakin, S.1
-
19
-
-
0035266243
-
ErbB2 overexpression on occult metastatic cells in bone marrow predicts poor clinical outcome of stage I-III breast cancer patients
-
Braun, S. et al. ErbB2 overexpression on occult metastatic cells in bone marrow predicts poor clinical outcome of stage I-III breast cancer patients. Cancer Res. 61, 1890-1895 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 1890-1895
-
-
Braun, S.1
-
20
-
-
84872048462
-
Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer
-
Gasch, C. et al. Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer. Clin. Chem. 59, 252-260 (2013).
-
(2013)
Clin. Chem.
, vol.59
, pp. 252-260
-
-
Gasch, C.1
-
21
-
-
84869067183
-
Relief of profound feedback inhibition of mitogenic signaling by RAF inhibitors attenuates their activity in BRAFV600E melanomas
-
Lito, P. et al. Relief of profound feedback inhibition of mitogenic signaling by RAF inhibitors attenuates their activity in BRAFV600E melanomas. Cancer Cell 22, 668-682 (2012).
-
(2012)
Cancer Cell
, vol.22
, pp. 668-682
-
-
Lito, P.1
-
22
-
-
33751252276
-
Cancer metastasis: Building a framework
-
Gupta, G.P. & Massague, J. Cancer metastasis: building a framework. Cell 127, 679-695 (2006).
-
(2006)
Cell
, vol.127
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
23
-
-
0036674501
-
Dissemination and growth of cancer cells in metastatic sites
-
Chambers, A.F., Groom, A.C. & MacDonald, I.C. Dissemination and growth of cancer cells in metastatic sites. Nat. Rev. Cancer 2, 563-572 (2002).
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 563-572
-
-
Chambers, A.F.1
Groom, A.C.2
MacDonald, I.C.3
-
24
-
-
0038049137
-
Tumour-cell invasion and migration: Diversity and escape mechanisms
-
Friedl, P. & Wolf, K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat. Rev. Cancer 3, 362-374 (2003).
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 362-374
-
-
Friedl, P.1
Wolf, K.2
-
25
-
-
84864886120
-
Classifying collective cancer cell invasion
-
Friedl, P., Locker, J., Sahai, E. & Segall, J.E. Classifying collective cancer cell invasion. Nat. Cell Biol. 14, 777-783 (2012).
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 777-783
-
-
Friedl, P.1
Locker, J.2
Sahai, E.3
Segall, J.E.4
-
26
-
-
33749024777
-
Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
-
Christiansen, J.J. & Rajasekaran, A.K. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res. 66, 8319-8326 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 8319-8326
-
-
Christiansen, J.J.1
Rajasekaran, A.K.2
-
27
-
-
70449526719
-
Localized and reversible TGFb signalling switches breast cancer cells from cohesive to single cell motility
-
Giampieri, S. et al. Localized and reversible TGFb signalling switches breast cancer cells from cohesive to single cell motility. Nat. Cell Biol. 11, 1287-1296 (2009).
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1287-1296
-
-
Giampieri, S.1
-
28
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery, J.P., Acloque, H., Huang, R.Y. & Nieto, M.A. Epithelial-mesenchymal transitions in development and disease. Cell 139, 871-890 (2009).
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
29
-
-
84878595514
-
Control of metastatic progression by microRNA regulatory networks
-
Pencheva, N. & Tavazoie, S.F. Control of metastatic progression by microRNA regulatory networks. Nat. Cell Biol. 15, 546-554 (2013).
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 546-554
-
-
Pencheva, N.1
Tavazoie, S.F.2
-
30
-
-
84887456252
-
Epigenetics of epithelial-mesenchymal plasticity in cancer
-
Tam, W.L. & Weinberg, R.A. Epigenetics of epithelial-mesenchymal plasticity in cancer. Nat. Med. 19, 1438-1449 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 1438-1449
-
-
Tam, W.L.1
Weinberg, R.A.2
-
31
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
De Craene, B. & Berx, G. Regulatory networks defining EMT during cancer initiation and progression. Nat. Rev. Cancer 13, 97-110 (2013).
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 97-110
-
-
De Craene, B.1
Berx, G.2
-
32
-
-
84861527239
-
To differentiate or not-routes towards metastasis
-
Brabletz, T. To differentiate or not-routes towards metastasis. Nat. Rev. Cancer 12, 425-436 (2012).
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 425-436
-
-
Brabletz, T.1
-
33
-
-
84866324123
-
Cancer stem cells and epithelial-mesenchymal transition: Concepts and molecular links
-
Scheel, C. & Weinberg, R.A. Cancer stem cells and epithelial-mesenchymal transition: concepts and molecular links. Semin. Cancer Biol. 22, 396-403 (2012).
-
(2012)
Semin. Cancer Biol.
, vol.22
, pp. 396-403
-
-
Scheel, C.1
Weinberg, R.A.2
-
34
-
-
79955420293
-
Cancer theory faces doubts
-
Ledford, H. Cancer theory faces doubts. Nature 472, 273 (2011).
-
(2011)
Nature
, vol.472
, Issue.273
-
-
Ledford, H.1
-
35
-
-
0035964349
-
Variable b-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
-
Brabletz, T. et al. Variable b-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc. Natl. Acad. Sci. USA 98, 10356-10361 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10356-10361
-
-
Brabletz, T.1
-
36
-
-
84867985453
-
Plasticity of disseminating cancer cells in patients with epithelial malignancies
-
Bednarz-Knoll, N., Alix-Panabieres, C. & Pantel, K. Plasticity of disseminating cancer cells in patients with epithelial malignancies. Cancer Metastasis Rev. 31, 673-687 (2012).
-
(2012)
Cancer Metastasis Rev.
, vol.31
, pp. 673-687
-
-
Bednarz-Knoll, N.1
Alix-Panabieres, C.2
Pantel, K.3
-
37
-
-
84875999237
-
Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis
-
Yokobori, T. et al. Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis. Cancer Res. 73, 2059-2069 (2013).
-
(2013)
Cancer Res.
, vol.73
, pp. 2059-2069
-
-
Yokobori, T.1
-
38
-
-
84873811988
-
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
-
Yu, M. et al. Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science 339, 580-584 (2013).
-
(2013)
Science
, vol.339
, pp. 580-584
-
-
Yu, M.1
-
39
-
-
77950931419
-
Matrix metalloproteinases: Regulators of the tumor microenvironment
-
Kessenbrock, K., Plaks, V. & Werb, Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 141, 52-67 (2010).
-
(2010)
Cell
, vol.141
, pp. 52-67
-
-
Kessenbrock, K.1
Plaks, V.2
Werb, Z.3
-
40
-
-
0037136543
-
Heritability of mammographic density, a risk factor for breast cancer
-
Boyd, N.F. et al. Heritability of mammographic density, a risk factor for breast cancer. N. Engl. J. Med. 347, 886-894 (2002).
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 886-894
-
-
Boyd, N.F.1
-
41
-
-
44149123099
-
Collagen density promotes mammary tumor initiation and progression
-
Provenzano, P.P. et al. Collagen density promotes mammary tumor initiation and progression. BMC Med. 6, 11 (2008).
-
(2008)
BMC Med.
, vol.6
, pp. 11
-
-
Provenzano, P.P.1
-
42
-
-
70450222098
-
Matrix crosslinking forces tumor progression by enhancing integrin signaling
-
Levental, K.R. et al. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 139, 891-906 (2009).
-
(2009)
Cell
, vol.139
, pp. 891-906
-
-
Levental, K.R.1
-
43
-
-
78650488264
-
LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling
-
Gao, Y. et al. LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling. Proc. Natl. Acad. Sci. USA 107, 18892-18897 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 18892-18897
-
-
Gao, Y.1
-
44
-
-
84877899680
-
Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis
-
Gilkes, D.M. et al. Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis. Mol. Cancer Res. 11, 456-466 (2013).
-
(2013)
Mol. Cancer Res.
, vol.11
, pp. 456-466
-
-
Gilkes, D.M.1
-
45
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
Erler, J.T. et al. Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 440, 1222-1226 (2006).
-
(2006)
Nature
, vol.440
, pp. 1222-1226
-
-
Erler, J.T.1
-
46
-
-
84859949610
-
The extracellular matrix: A dynamic niche in cancer progression
-
Lu, P., Weaver, V.M. & Werb, Z. The extracellular matrix: a dynamic niche in cancer progression. J. Cell Biol. 196, 395-406 (2012).
-
(2012)
J. Cell Biol.
, vol.196
, pp. 395-406
-
-
Lu, P.1
Weaver, V.M.2
Werb, Z.3
-
47
-
-
81255188940
-
Tumor angiogenesis: Molecular pathways and therapeutic targets
-
Weis, S.M. & Cheresh, D.A. Tumor angiogenesis: molecular pathways and therapeutic targets. Nat. Med. 17, 1359-1370 (2011).
-
(2011)
Nat. Med.
, vol.17
, pp. 1359-1370
-
-
Weis, S.M.1
Cheresh, D.A.2
-
48
-
-
78651446926
-
Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling
-
Sonoshita, M. et al. Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling. Cancer Cell 19, 125-137 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 125-137
-
-
Sonoshita, M.1
-
49
-
-
84871942211
-
Cdc42 promotes transendothelial migration of cancer cells through b1 integrin
-
Reymond, N. et al. Cdc42 promotes transendothelial migration of cancer cells through b1 integrin. J. Cell Biol. 199, 653-668 (2012).
-
(2012)
J. Cell Biol.
, vol.199
, pp. 653-668
-
-
Reymond, N.1
-
50
-
-
80054686286
-
Tumor metastasis: Molecular insights and evolving paradigms
-
Valastyan, S. & Weinberg, R.A. Tumor metastasis: molecular insights and evolving paradigms. Cell 147, 275-292 (2011).
-
(2011)
Cell
, vol.147
, pp. 275-292
-
-
Valastyan, S.1
Weinberg, R.A.2
-
51
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
Minn, A.J. et al. Genes that mediate breast cancer metastasis to lung. Nature 436, 518-524 (2005).
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
-
52
-
-
41149157649
-
TGFb primes breast tumors for lung metastasis seeding through angiopoietin-like 4
-
Padua, D. et al. TGFb primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell 133, 66-77 (2008).
-
(2008)
Cell
, vol.133
, pp. 66-77
-
-
Padua, D.1
-
53
-
-
34147220392
-
Mediators of vascular remodelling co-opted for sequential steps in lung metastasis
-
Gupta, G.P. et al. Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature 446, 765-770 (2007).
-
(2007)
Nature
, vol.446
, pp. 765-770
-
-
Gupta, G.P.1
-
54
-
-
4344627055
-
Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB
-
Douma, S. et al. Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB. Nature 430, 1034-1039 (2004).
-
(2004)
Nature
, vol.430
, pp. 1034-1039
-
-
Douma, S.1
-
55
-
-
67649300721
-
Genes that mediate breast cancer metastasis to the brain
-
Bos, P.D. et al. Genes that mediate breast cancer metastasis to the brain. Nature 459, 1005-1009 (2009).
-
(2009)
Nature
, vol.459
, pp. 1005-1009
-
-
Bos, P.D.1
-
56
-
-
80054725681
-
Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs
-
Chen, Q., Zhang, X.H. & Massague, J. Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs. Cancer Cell 20, 538-549 (2011).
-
(2011)
Cancer Cell
, vol.20
, pp. 538-549
-
-
Chen, Q.1
Zhang, X.H.2
Massague, J.3
-
57
-
-
80053239972
-
Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells
-
Grabinski, N. et al. Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells. Cell. Signal. 23, 1952-1960 (2011).
-
(2011)
Cell. Signal.
, vol.23
, pp. 1952-1960
-
-
Grabinski, N.1
-
58
-
-
84859158880
-
The CD47-SIRPa pathway in cancer immune evasion and potential therapeutic implications
-
Chao, M.P., Weissman, I.L. & Majeti, R. The CD47-SIRPa pathway in cancer immune evasion and potential therapeutic implications. Curr. Opin. Immunol. 24, 225-232 (2012).
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 225-232
-
-
Chao, M.P.1
Weissman, I.L.2
Majeti, R.3
-
59
-
-
84880270290
-
Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay
-
Baccelli, I. et al. Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay. Nat. Biotechnol. 31, 539-544 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 539-544
-
-
Baccelli, I.1
-
60
-
-
84879797224
-
Engineered SIRPa variants as immunotherapeutic adjuvants to anticancer antibodies
-
Weiskopf, K. et al. Engineered SIRPa variants as immunotherapeutic adjuvants to anticancer antibodies. Science 341, 88-91 (2013).
-
(2013)
Science
, vol.341
, pp. 88-91
-
-
Weiskopf, K.1
-
61
-
-
2942538264
-
Dissecting the metastatic cascade
-
Pantel, K. & Brakenhoff, R.H. Dissecting the metastatic cascade. Nat. Rev. Cancer 4, 448-456 (2004).
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 448-456
-
-
Pantel, K.1
Brakenhoff, R.H.2
-
62
-
-
35548936833
-
Models mechanisms and clinical evidence for cancer dormancy
-
Aguirre-Ghiso, J.A. Models, mechanisms and clinical evidence for cancer dormancy. Nat. Rev. Cancer 7, 834-846 (2007).
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
63
-
-
84866242179
-
The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions
-
Shibue, T., Brooks, M.W., Inan, M.F., Reinhardt, F. & Weinberg, R.A. The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions. Cancer Discov. 2, 706-721 (2012).
-
(2012)
Cancer Discov.
, vol.2
, pp. 706-721
-
-
Shibue, T.1
Brooks, M.W.2
Inan, M.F.3
Reinhardt, F.4
Weinberg, R.A.5
-
64
-
-
67649849871
-
Integrin b1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs
-
Shibue, T. & Weinberg, R.A. Integrin b1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proc. Natl. Acad. Sci. USA 106, 10290-10295 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 10290-10295
-
-
Shibue, T.1
Weinberg, R.A.2
-
65
-
-
51049119424
-
Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton
-
Barkan, D. et al. Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton. Cancer Res. 68, 6241-6250 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 6241-6250
-
-
Barkan, D.1
-
66
-
-
77955021301
-
Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment
-
Barkan, D. et al. Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment. Cancer Res. 70, 5706-5716 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 5706-5716
-
-
Barkan, D.1
-
67
-
-
0002460807
-
Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling
-
Aguirre Ghiso, J.A., Kovalski, K. & Ossowski, L. Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling. J. Cell Biol. 147, 89-104 (1999).
-
(1999)
J. Cell Biol.
, vol.147
, pp. 89-104
-
-
Aguirre Ghiso, J.A.1
Kovalski, K.2
Ossowski, L.3
-
68
-
-
33751198957
-
Tumor cell dormancy induced by p38SAPK and ER-stress signaling: An adaptive advantage for metastatic cells?
-
Ranganathan, A.C., Adam, A.P., Zhang, L. & Aguirre-Ghiso, J.A. Tumor cell dormancy induced by p38SAPK and ER-stress signaling: an adaptive advantage for metastatic cells? Cancer Biol. Ther. 5, 729-735 (2006).
-
(2006)
Cancer Biol. Ther.
, vol.5
, pp. 729-735
-
-
Ranganathan, A.C.1
Adam, A.P.2
Zhang, L.3
Aguirre-Ghiso, J.A.4
-
69
-
-
80052867880
-
ERK1/2 and p38a/b signaling in tumor cell quiescence: Opportunities to control dormant residual disease
-
Sosa, M.S., Avivar-Valderas, A., Bragado, P., Wen, H.C. & Aguirre-Ghiso, J.A. ERK1/2 and p38a/b signaling in tumor cell quiescence: opportunities to control dormant residual disease. Clin. Cancer Res. 17, 5850-5857 (2011).
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 5850-5857
-
-
Sosa, M.S.1
Avivar-Valderas, A.2
Bragado, P.3
Wen, H.C.4
Aguirre-Ghiso, J.A.5
-
70
-
-
84865218588
-
The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites
-
Gao, H. et al. The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites. Cell 150, 764-779 (2012).
-
(2012)
Cell
, vol.150
, pp. 764-779
-
-
Gao, H.1
-
71
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang, Y. et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3, 537-549 (2003).
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
-
72
-
-
79751472667
-
Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
-
Sethi, N., Dai, X., Winter, C.G. & Kang, Y. Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell 19, 192-205 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 192-205
-
-
Sethi, N.1
Dai, X.2
Winter, C.G.3
Kang, Y.4
-
73
-
-
79952759508
-
Claudin-2 is selectively enriched in and promotes the formation of breast cancer liver metastases through engagement of integrin complexes
-
Tabariès, S. et al. Claudin-2 is selectively enriched in and promotes the formation of breast cancer liver metastases through engagement of integrin complexes. Oncogene 30, 1318-1328 (2011).
-
(2011)
Oncogene
, vol.30
, pp. 1318-1328
-
-
Tabariès, S.1
-
74
-
-
83455208311
-
VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging a4b1-positive osteoclast progenitors
-
Lu, X. et al. VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging a4b1-positive osteoclast progenitors. Cancer Cell 20, 701-714 (2011).
-
(2011)
Cancer Cell
, vol.20
, pp. 701-714
-
-
Lu, X.1
-
75
-
-
79953331206
-
Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow
-
Shiozawa, Y. et al. Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow. J. Clin. Invest. 121, 1298-1312 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1298-1312
-
-
Shiozawa, Y.1
-
76
-
-
33750306612
-
Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
-
Balic, M. et al. Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin. Cancer Res. 12, 5615-5621 (2006).
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 5615-5621
-
-
Balic, M.1
-
77
-
-
84858590826
-
Accessories to the crime: Functions of cells recruited to the tumor microenvironment
-
Hanahan, D. & Coussens, L.M. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 21, 309-322 (2012).
-
(2012)
Cancer Cell
, vol.21
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
78
-
-
84887444879
-
Microenvironmental regulation of tumor progression and metastasis
-
Quail, D.F. & Joyce, J.A. Microenvironmental regulation of tumor progression and metastasis. Nat. Med. 19, 45-59 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 45-59
-
-
Quail, D.F.1
Joyce, J.A.2
-
79
-
-
43249121177
-
Stromal gene expression predicts clinical outcome in breast cancer
-
Finak, G. et al. Stromal gene expression predicts clinical outcome in breast cancer. Nat. Med. 14, 518-527 (2008).
-
(2008)
Nat. Med.
, vol.14
, pp. 518-527
-
-
Finak, G.1
-
80
-
-
0038481970
-
The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
-
Fidler, I.J. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat. Rev. Cancer 3, 453-458 (2003).
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 453-458
-
-
Fidler, I.J.1
-
81
-
-
4944229701
-
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
-
Wyckoff, J. et al. A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res. 64, 7022-7029 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 7022-7029
-
-
Wyckoff, J.1
-
82
-
-
67651160649
-
CD4+ T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
-
DeNardo, D.G. et al. CD4+ T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 16, 91-102 (2009).
-
(2009)
Cancer Cell
, vol.16
, pp. 91-102
-
-
Denardo, D.G.1
-
83
-
-
79953305102
-
Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion
-
Dirat, B. et al. Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion. Cancer Res. 71, 2455-2465 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 2455-2465
-
-
Dirat, B.1
-
84
-
-
34948896045
-
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
-
Karnoub, A.E. et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 449, 557-563 (2007).
-
(2007)
Nature
, vol.449
, pp. 557-563
-
-
Karnoub, A.E.1
-
85
-
-
81255157465
-
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
-
Nieman, K.M. et al. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat. Med. 17, 1498-1503 (2011).
-
(2011)
Nat. Med.
, vol.17
, pp. 1498-1503
-
-
Nieman, K.M.1
-
86
-
-
84871563123
-
Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
-
Luga, V. et al. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell 151, 1542-1556 (2012).
-
(2012)
Cell
, vol.151
, pp. 1542-1556
-
-
Luga, V.1
-
87
-
-
78650373860
-
Hypoxia and hypoxia-inducible factors: Master regulators of metastasis
-
Lu, X. & Kang, Y. Hypoxia and hypoxia-inducible factors: master regulators of metastasis. Clin. Cancer Res. 16, 5928-5935 (2010).
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 5928-5935
-
-
Lu, X.1
Kang, Y.2
-
88
-
-
79952193038
-
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling
-
Tan, W. et al. Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling. Nature 470, 548-553 (2011).
-
(2011)
Nature
, vol.470
, pp. 548-553
-
-
Tan, W.1
-
89
-
-
84856088337
-
EMT and dissemination precede pancreatic tumor formation
-
Rhim, A.D. et al. EMT and dissemination precede pancreatic tumor formation. Cell 148, 349-361 (2012).
-
(2012)
Cell
, vol.148
, pp. 349-361
-
-
Rhim, A.D.1
-
90
-
-
84862909156
-
Endothelial cell HIF-1a and HIF-2a differentially regulate metastatic success
-
Branco-Price, C. et al. Endothelial cell HIF-1a and HIF-2a differentially regulate metastatic success. Cancer Cell 21, 52-65 (2012).
-
(2012)
Cancer Cell
, vol.21
, pp. 52-65
-
-
Branco-Price, C.1
-
91
-
-
84869021181
-
Dependency of colorectal cancer on a TGF-b-driven program in stromal cells for metastasis initiation
-
Calon, A. et al. Dependency of colorectal cancer on a TGF-b-driven program in stromal cells for metastasis initiation. Cancer Cell 22, 571-584 (2012).
-
(2012)
Cancer Cell
, vol.22
, pp. 571-584
-
-
Calon, A.1
-
92
-
-
72449176846
-
Molecular origins of cancer: Molecular basis of colorectal cancer
-
Markowitz, S.D. & Bertagnolli, M.M. Molecular origins of cancer: molecular basis of colorectal cancer. N. Engl. J. Med. 361, 2449-2460 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2449-2460
-
-
Markowitz, S.D.1
Bertagnolli, M.M.2
-
93
-
-
84862007577
-
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
-
Peinado, H. et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat. Med. 18, 883-891 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 883-891
-
-
Peinado, H.1
-
94
-
-
79960960417
-
Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche
-
Grange, C. et al. Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res. 71, 5346-5356 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 5346-5356
-
-
Grange, C.1
-
95
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
Kaplan, R.N. et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438, 820-827 (2005).
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.N.1
-
96
-
-
33751504690
-
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
-
Hiratsuka, S., Watanabe, A., Aburatani, H. & Maru, Y. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat. Cell Biol. 8, 1369-1375 (2006).
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1369-1375
-
-
Hiratsuka, S.1
Watanabe, A.2
Aburatani, H.3
Maru, Y.4
-
97
-
-
55549128598
-
The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase
-
Hiratsuka, S. et al. The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase. Nat. Cell Biol. 10, 1349-1355 (2008).
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1349-1355
-
-
Hiratsuka, S.1
-
98
-
-
63049121364
-
The metastatic niche: Adapting the foreign soil
-
Psaila, B. & Lyden, D. The metastatic niche: adapting the foreign soil. Nat. Rev. Cancer 9, 285-293 (2009).
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 285-293
-
-
Psaila, B.1
Lyden, D.2
-
99
-
-
84877602573
-
Bone marrow-derived Gr1+ cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1
-
Catena, R. et al. Bone marrow-derived Gr1+ cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1. Cancer Discov. 3, 578-589 (2013).
-
(2013)
Cancer Discov.
, vol.3
, pp. 578-589
-
-
Catena, R.1
-
100
-
-
33644827383
-
Bone-marrow haematopoietic-stem-cell niches
-
Wilson, A. & Trumpp, A. Bone-marrow haematopoietic-stem-cell niches. Nat. Rev. Immunol. 6, 93-106 (2006).
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 93-106
-
-
Wilson, A.1
Trumpp, A.2
-
101
-
-
84880332704
-
The perivascular niche regulates breast tumour dormancy
-
Ghajar, C.M. et al. The perivascular niche regulates breast tumour dormancy. Nat. Cell Biol. 15, 807-817 (2013).
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 807-817
-
-
Ghajar, C.M.1
-
102
-
-
73849129203
-
Real-time imaging reveals the single steps of brain metastasis formation
-
Kienast, Y. et al. Real-time imaging reveals the single steps of brain metastasis formation. Nat. Med. 16, 116-122 (2010).
-
(2010)
Nat. Med.
, vol.16
, pp. 116-122
-
-
Kienast, Y.1
-
103
-
-
38149006909
-
Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis
-
Gao, D. et al. Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science 319, 195-198 (2008).
-
(2008)
Science
, vol.319
, pp. 195-198
-
-
Gao, D.1
-
104
-
-
0035160312
-
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
-
Lyden, D. et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat. Med. 7, 1194-1201 (2001).
-
(2001)
Nat. Med.
, vol.7
, pp. 1194-1201
-
-
Lyden, D.1
-
105
-
-
0033554723
-
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts
-
Lyden, D. et al. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature 401, 670-677 (1999).
-
(1999)
Nature
, vol.401
, pp. 670-677
-
-
Lyden, D.1
-
106
-
-
75149149879
-
Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors
-
Butler, J.M., Kobayashi, H. & Rafii, S. Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors. Nat. Rev. Cancer 10, 138-146 (2010).
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 138-146
-
-
Butler, J.M.1
Kobayashi, H.2
Rafii, S.3
-
107
-
-
84859633736
-
Cell lineage specification in tumor progression and metastasis
-
Cao, P.D., Cheung, W.K. & Nguyen, D.X. Cell lineage specification in tumor progression and metastasis. Discov. Med. 12, 329-340 (2011).
-
(2011)
Discov. Med.
, vol.12
, pp. 329-340
-
-
Cao, P.D.1
Cheung, W.K.2
Nguyen, D.X.3
-
108
-
-
79955584983
-
Suppression of lung adenocarcinoma progression by Nkx2-1
-
Winslow, M.M. et al. Suppression of lung adenocarcinoma progression by Nkx2-1. Nature 473, 101-104 (2011).
-
(2011)
Nature
, vol.473
, pp. 101-104
-
-
Winslow, M.M.1
-
109
-
-
84876835924
-
Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma
-
Snyder, E.L. et al. Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma. Mol. Cell 50, 185-199 (2013).
-
(2013)
Mol. Cell
, vol.50
, pp. 185-199
-
-
Snyder, E.L.1
-
110
-
-
84878990582
-
Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis
-
Cheung, W.K. et al. Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis. Cancer Cell 23, 725-738 (2013).
-
(2013)
Cancer Cell
, vol.23
, pp. 725-738
-
-
Cheung, W.K.1
-
111
-
-
38549131901
-
GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model
-
Kouros-Mehr, H. et al. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell 13, 141-152 (2008).
-
(2008)
Cancer Cell
, vol.13
, pp. 141-152
-
-
Kouros-Mehr, H.1
-
112
-
-
84873364088
-
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression
-
Chou, J. et al. GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat. Cell Biol. 15, 201-213 (2013).
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 201-213
-
-
Chou, J.1
-
113
-
-
84869045299
-
Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2
-
Chakrabarti, R. et al. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. Nat. Cell Biol. 14, 1212-1222 (2012).
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 1212-1222
-
-
Chakrabarti, R.1
-
114
-
-
84857817163
-
Slug and Sox9 cooperatively determine the mammary stem cell state
-
Guo, W. et al. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell 148, 1015-1028 (2012).
-
(2012)
Cell
, vol.148
, pp. 1015-1028
-
-
Guo, W.1
-
115
-
-
67649662201
-
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis
-
Nguyen, D.X. et al. WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell 138, 51-62 (2009).
-
(2009)
Cell
, vol.138
, pp. 51-62
-
-
Nguyen, D.X.1
-
116
-
-
79960117895
-
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
-
Oskarsson, T. et al. Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. Nat. Med. 17, 867-874 (2011).
-
(2011)
Nat. Med.
, vol.17
, pp. 867-874
-
-
Oskarsson, T.1
-
117
-
-
54249097017
-
Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells
-
Pratap, J. et al. Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells. Cancer Res. 68, 7795-7802 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 7795-7802
-
-
Pratap, J.1
-
118
-
-
37649001973
-
ID genes mediate tumor reinitiation during breast cancer lung metastasis
-
Gupta, G.P. et al. ID genes mediate tumor reinitiation during breast cancer lung metastasis. Proc. Natl. Acad. Sci. USA 104, 19506-19511 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 19506-19511
-
-
Gupta, G.P.1
-
119
-
-
44449084242
-
Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response
-
Swarbrick, A., Roy, E., Allen, T. & Bishop, J.M. Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response. Proc. Natl. Acad. Sci. USA 105, 5402-5407 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 5402-5407
-
-
Swarbrick, A.1
Roy, E.2
Allen, T.3
Bishop, J.M.4
-
120
-
-
84855425160
-
Interactions between cancer stem cells and their niche govern metastatic colonization
-
Malanchi, I. et al. Interactions between cancer stem cells and their niche govern metastatic colonization. Nature 481, 85-89 (2012).
-
(2012)
Nature
, vol.481
, pp. 85-89
-
-
Malanchi, I.1
-
121
-
-
80053160728
-
VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization
-
O'Connell, J.T. et al. VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization. Proc. Natl. Acad. Sci. USA 108, 16002-16007 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 16002-16007
-
-
O'Connell, J.T.1
-
122
-
-
76249097588
-
Incorporation of tenascin-C into the extracellular matrix by periostin underlies an extracellular meshwork architecture
-
Kii, I. et al. Incorporation of tenascin-C into the extracellular matrix by periostin underlies an extracellular meshwork architecture. J. Biol. Chem. 285, 2028-2039 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 2028-2039
-
-
Kii, I.1
-
123
-
-
84869042621
-
A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis
-
Reticker-Flynn, N.E. et al. A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nat. Commun. 3, 1122 (2012).
-
(2012)
Nat. Commun.
, vol.3
, pp. 1122
-
-
Reticker-Flynn, N.E.1
-
124
-
-
84875537133
-
Epigenetic reprogramming in cancer
-
Suvà, M.L., Riggi, N. & Bernstein, B.E. Epigenetic reprogramming in cancer. Science 339, 1567-1570 (2013).
-
(2013)
Science
, vol.339
, pp. 1567-1570
-
-
Suvà, M.L.1
Riggi, N.2
Bernstein, B.E.3
-
125
-
-
84872376809
-
Suppression of miRNA-708 by polycomb group promotes metastases by calcium-induced cell migration
-
Ryu, S. et al. Suppression of miRNA-708 by polycomb group promotes metastases by calcium-induced cell migration. Cancer Cell 23, 63-76 (2013).
-
(2013)
Cancer Cell
, vol.23
, pp. 63-76
-
-
Ryu, S.1
-
126
-
-
84878983107
-
Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming
-
Tiwari, N. et al. Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming. Cancer Cell 23, 768-783 (2013).
-
(2013)
Cancer Cell
, vol.23
, pp. 768-783
-
-
Tiwari, N.1
-
127
-
-
77951118936
-
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
-
Gupta, R.A. et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 464, 1071-1076 (2010).
-
(2010)
Nature
, vol.464
, pp. 1071-1076
-
-
Gupta, R.A.1
-
128
-
-
84860578009
-
Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
-
Celià-Terrassa, T. et al. Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells. J. Clin. Invest. 122, 1849-1868 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1849-1868
-
-
Celià-Terrassa, T.1
-
129
-
-
84870816403
-
Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1
-
Ocaña, O.H. et al. Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1. Cancer Cell 22, 709-724 (2012).
-
(2012)
Cancer Cell
, vol.22
, pp. 709-724
-
-
Ocaña, O.H.1
-
130
-
-
84870845421
-
Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
-
Tsai, J.H., Donaher, J.L., Murphy, D.A., Chau, S. & Yang, J. Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis. Cancer Cell 22, 725-736 (2012).
-
(2012)
Cancer Cell
, vol.22
, pp. 725-736
-
-
Tsai, J.H.1
Donaher, J.L.2
Murphy, D.A.3
Chau, S.4
Yang, J.5
-
131
-
-
57749092869
-
Epithelial-mesenchymal transition induced by growth suppressor p12CDK2-AP1 promotes tumor cell local invasion but suppresses distant colony growth
-
Tsuji, T. et al. Epithelial-mesenchymal transition induced by growth suppressor p12CDK2-AP1 promotes tumor cell local invasion but suppresses distant colony growth. Cancer Res. 68, 10377-10386 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 10377-10386
-
-
Tsuji, T.1
-
132
-
-
80052470207
-
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
-
Korpal, M. et al. Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat. Med. 17, 1101-1108 (2011).
-
(2011)
Nat. Med.
, vol.17
, pp. 1101-1108
-
-
Korpal, M.1
-
133
-
-
35848963863
-
Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition
-
Mejlvang, J. et al. Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition. Mol. Biol. Cell 18, 4615-4624 (2007).
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 4615-4624
-
-
Mejlvang, J.1
-
134
-
-
84857097186
-
Changes in keratin expression during metastatic progression of breast cancer: Impact on the detection of circulating tumor cells
-
Joosse, S.A. et al. Changes in keratin expression during metastatic progression of breast cancer: impact on the detection of circulating tumor cells. Clin. Cancer Res. 18, 993-1003 (2012).
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 993-1003
-
-
Joosse, S.A.1
-
135
-
-
84877726784
-
The identification and characterization of breast cancer CTCs competent for brain metastasis
-
Zhang, L. et al. The identification and characterization of breast cancer CTCs competent for brain metastasis. Sci. Transl. Med. 5, 180ra148 (2013).
-
(2013)
Sci. Transl. Med.
, vol.5
, pp. 180-148
-
-
Zhang, L.1
-
136
-
-
84897977206
-
Multilayer control of the EMT master regulators
-
published online doi:10.1038/onc.2013.128 (22 April 2013
-
Zheng, H. & Kang, Y. Multilayer control of the EMT master regulators. Oncogene published online, doi:10.1038/onc.2013.128 (22 April 2013).
-
Oncogene
-
-
Zheng, H.1
Kang, Y.2
-
137
-
-
79953147370
-
A perspective on cancer cell metastasis
-
Chaffer, C.L. & Weinberg, R.A. A perspective on cancer cell metastasis. Science 331, 1559-1564 (2011).
-
(2011)
Science
, vol.331
, pp. 1559-1564
-
-
Chaffer, C.L.1
Weinberg, R.A.2
-
138
-
-
0031215023
-
The epithelial cell default-phenotype hypothesis and its implications for cancer
-
Frisch, S.M. The epithelial cell default-phenotype hypothesis and its implications for cancer. Bioessays 19, 705-709 (1997).
-
(1997)
Bioessays
, vol.19
, pp. 705-709
-
-
Frisch, S.M.1
-
139
-
-
84858199187
-
Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition
-
Gao, D. et al. Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition. Cancer Res. 72, 1384-1394 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 1384-1394
-
-
Gao, D.1
-
140
-
-
34247217230
-
Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin
-
Yates, C.C., Shepard, C.R., Stolz, D.B. & Wells, A. Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin. Br. J. Cancer 96, 1246-1252 (2007).
-
(2007)
Br. J. Cancer
, vol.96
, pp. 1246-1252
-
-
Yates, C.C.1
Shepard, C.R.2
Stolz, D.B.3
Wells, A.4
-
141
-
-
77954304397
-
Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition
-
Chao, Y.L., Shepard, C.R. & Wells, A. Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition. Mol. Cancer 9, 179 (2010).
-
(2010)
Mol. Cancer
, vol.9
, pp. 179
-
-
Chao, Y.L.1
Shepard, C.R.2
Wells, A.3
-
142
-
-
37349079197
-
Systemic spread is an early step in breast cancer
-
Hüsemann, Y. et al. Systemic spread is an early step in breast cancer. Cancer Cell 13, 58-68 (2008).
-
(2008)
Cancer Cell
, vol.13
, pp. 58-68
-
-
Hüsemann, Y.1
-
143
-
-
77953225810
-
Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma
-
Eyles, J. et al. Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma. J. Clin. Invest. 120, 2030-2039 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2030-2039
-
-
Eyles, J.1
-
144
-
-
84856233963
-
Hematogenous and lymphatic tumor cell dissemination may be detected in patients diagnosed with ductal carcinoma in situ of the breast
-
Banys, M. et al. Hematogenous and lymphatic tumor cell dissemination may be detected in patients diagnosed with ductal carcinoma in situ of the breast. Breast Cancer Res. Treat. 131, 801-808 (2012).
-
(2012)
Breast Cancer Res. Treat.
, vol.131
, pp. 801-808
-
-
Banys, M.1
-
145
-
-
80052970594
-
Disseminated tumor cells in the bone marrow of patients with ductal carcinoma in situ
-
Sanger, N. et al. Disseminated tumor cells in the bone marrow of patients with ductal carcinoma in situ. Int. J. Cancer 129, 2522-2526 (2011).
-
(2011)
Int. J. Cancer
, vol.129
, pp. 2522-2526
-
-
Sanger, N.1
-
146
-
-
73449133770
-
Genetic disparity between primary tumours, disseminated tumour cells, and manifest metastasis
-
Stoecklein, N.H. & Klein, C.A. Genetic disparity between primary tumours, disseminated tumour cells, and manifest metastasis. Int. J. Cancer 126, 589-598 (2010).
-
(2010)
Int. J. Cancer
, vol.126
, pp. 589-598
-
-
Stoecklein, N.H.1
Klein, C.A.2
-
147
-
-
84875159380
-
Pancreatic cancer genomics: Insights and opportunities for clinical translation
-
Makohon-Moore, A., Brosnan, J.A. & Iacobuzio-Donahue, C.A. Pancreatic cancer genomics: insights and opportunities for clinical translation. Genome Med. 5, 26 (2013).
-
(2013)
Genome Med.
, vol.5
, pp. 26
-
-
Makohon-Moore, A.1
Brosnan, J.A.2
Iacobuzio-Donahue, C.A.3
-
148
-
-
72249093615
-
Tumor self-seeding by circulating cancer cells
-
Kim, M.Y. et al. Tumor self-seeding by circulating cancer cells. Cell 139, 1315-1326 (2009).
-
(2009)
Cell
, vol.139
, pp. 1315-1326
-
-
Kim, M.Y.1
-
149
-
-
33746807641
-
Is cancer a disease of self-seeding?
-
Norton, L. & Massague, J. Is cancer a disease of self-seeding? Nat. Med. 12, 875-878 (2006).
-
(2006)
Nat. Med.
, vol.12
, pp. 875-878
-
-
Norton, L.1
Massague, J.2
-
150
-
-
23944466427
-
A pooled analysis of bone marrow micrometastasis in breast cancer
-
Braun, S. et al. A pooled analysis of bone marrow micrometastasis in breast cancer. N. Engl. J. Med. 353, 793-802 (2005).
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 793-802
-
-
Braun, S.1
-
151
-
-
50349096764
-
Disseminated tumor cells of breast cancer patients: A strong prognostic factor for distant and local relapse
-
Bidard, F.C. et al. Disseminated tumor cells of breast cancer patients: a strong prognostic factor for distant and local relapse. Clin. Cancer Res. 14, 3306-3311 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3306-3311
-
-
Bidard, F.C.1
-
152
-
-
77952305169
-
Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: An open label, randomised, phase 2 trial
-
Aft, R. et al. Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: an open label, randomised, phase 2 trial. Lancet Oncol. 11, 421-428 (2010).
-
(2010)
Lancet Oncol.
, vol.11
, pp. 421-428
-
-
Aft, R.1
-
153
-
-
60549097419
-
Endocrine therapy plus zoledronic acid in premenopausal breast cancer
-
Gnant, M. et al. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. N. Engl. J. Med. 360, 679-691 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 679-691
-
-
Gnant, M.1
-
154
-
-
79958065859
-
Clinical implications of cancer self-seeding
-
Comen, E., Norton, L. & Massague, J. Clinical implications of cancer self-seeding. Nat. Rev. Clin. Oncol. 8, 369-377 (2011).
-
(2011)
Nat. Rev. Clin. Oncol.
, vol.8
, pp. 369-377
-
-
Comen, E.1
Norton, L.2
Massague, J.3
-
155
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger, M. et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N. Engl. J. Med. 366, 883-892 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
-
156
-
-
84863230091
-
Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor
-
Xu, X. et al. Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. Cell 148, 886-895 (2012).
-
(2012)
Cell
, vol.148
, pp. 886-895
-
-
Xu, X.1
-
157
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding, L. et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 464, 999-1005 (2010).
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
-
158
-
-
84862776537
-
Clonal selection drives genetic divergence of metastatic medulloblastoma
-
Wu, X. et al. Clonal selection drives genetic divergence of metastatic medulloblastoma. Nature 482, 529-533 (2012).
-
(2012)
Nature
, vol.482
, pp. 529-533
-
-
Wu, X.1
-
159
-
-
67349257845
-
Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer
-
Liu, W. et al. Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat. Med. 15, 559-565 (2009).
-
(2009)
Nat. Med.
, vol.15
, pp. 559-565
-
-
Liu, W.1
-
160
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida, S. et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 467, 1114-1117 (2010).
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
-
161
-
-
84877865227
-
Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing
-
Heitzer, E. et al. Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing. Cancer Res. 73, 2965-2975 (2013).
-
(2013)
Cancer Res.
, vol.73
, pp. 2965-2975
-
-
Heitzer, E.1
-
162
-
-
78049380554
-
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
-
Campbell, P.J. et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature 467, 1109-1113 (2010).
-
(2010)
Nature
, vol.467
, pp. 1109-1113
-
-
Campbell, P.J.1
-
163
-
-
70349969478
-
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
-
Shah, S.P. et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature 461, 809-813 (2009).
-
(2009)
Nature
, vol.461
, pp. 809-813
-
-
Shah, S.P.1
-
164
-
-
84856536814
-
Primary colorectal cancers and their subsequent hepatic metastases are genetically different: Implications for selection of patients for targeted treatment
-
Vermaat, J.S. et al. Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment. Clin. Cancer Res. 18, 688-699 (2012).
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 688-699
-
-
Vermaat, J.S.1
-
165
-
-
0342887306
-
Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer
-
Kuukasjärvi, T. et al. Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer. Cancer Res. 57, 1597-1604 (1997).
-
(1997)
Cancer Res.
, vol.57
, pp. 1597-1604
-
-
Kuukasjärvi, T.1
-
166
-
-
84871461434
-
Genome-wide detection of single-nucleotide and copy-number variations of a single human cell
-
Zong, C., Lu, S., Chapman, A.R. & Xie, X.S. Genome-wide detection of single-nucleotide and copy-number variations of a single human cell. Science 338, 1622-1626 (2012).
-
(2012)
Science
, vol.338
, pp. 1622-1626
-
-
Zong, C.1
Lu, S.2
Chapman, A.R.3
Xie, X.S.4
-
167
-
-
79953766940
-
Tumour evolution inferred by single-cell sequencing
-
Navin, N. et al. Tumour evolution inferred by single-cell sequencing. Nature 472, 90-94 (2011).
-
(2011)
Nature
, vol.472
, pp. 90-94
-
-
Navin, N.1
-
168
-
-
2542474181
-
Genomic profiling of viable and proliferative micrometastatic cells from early-stage breast cancer patients
-
Gangnus, R., Langer, S., Breit, E., Pantel, K. & Speicher, M.R. Genomic profiling of viable and proliferative micrometastatic cells from early-stage breast cancer patients. Clin. Cancer Res. 10, 3457-3464 (2004).
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3457-3464
-
-
Gangnus, R.1
Langer, S.2
Breit, E.3
Pantel, K.4
Speicher, M.R.5
-
169
-
-
0037206022
-
Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer
-
Klein, C.A. et al. Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer. Lancet 360, 683-689 (2002).
-
(2002)
Lancet
, vol.360
, pp. 683-689
-
-
Klein, C.A.1
-
170
-
-
0038271868
-
From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression
-
Schmidt-Kittler, O. et al. From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression. Proc. Natl. Acad. Sci. USA 100, 7737-7742 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7737-7742
-
-
Schmidt-Kittler, O.1
-
171
-
-
19944426264
-
Circulating tumor cells in patients with breast cancer dormancy
-
Meng, S. et al. Circulating tumor cells in patients with breast cancer dormancy. Clin. Cancer Res. 10, 8152-8162 (2004).
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 8152-8162
-
-
Meng, S.1
-
172
-
-
84861716177
-
Perspective: The right trials
-
Steeg, P.S. Perspective: the right trials. Nature 485, S58-S59 (2012).
-
(2012)
Nature
, vol.485
-
-
Steeg, P.S.1
-
173
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
-
Coussens, L.M., Fingleton, B. & Matrisian, L.M. Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 295, 2387-2392 (2002).
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
174
-
-
57849134562
-
MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer
-
Hu, G. et al. MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell 15, 9-20 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 9-20
-
-
Hu, G.1
-
175
-
-
84863625224
-
A CXCL1 paracrine network links cancer chemoresistance and metastasis
-
Acharyya, S. et al. A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell 150, 165-178 (2012).
-
(2012)
Cell
, vol.150
, pp. 165-178
-
-
Acharyya, S.1
-
176
-
-
77958501473
-
DNA damage-mediated induction of a chemoresistant niche
-
Gilbert, L.A. & Hemann, M.T. DNA damage-mediated induction of a chemoresistant niche. Cell 143, 355-366 (2010).
-
(2010)
Cell
, vol.143
, pp. 355-366
-
-
Gilbert, L.A.1
Hemann, M.T.2
-
177
-
-
79957894276
-
Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
-
Carmeliet, P. & Jain, R.K. Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nat. Rev. Drug Discov. 10, 417-427 (2011).
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, pp. 417-427
-
-
Carmeliet, P.1
Jain, R.K.2
-
178
-
-
0033986270
-
Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients
-
Braun, S. et al. Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients. J. Clin. Oncol. 18, 80-86 (2000).
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 80-86
-
-
Braun, S.1
-
179
-
-
70350557303
-
Three-dimensional imaging and quantification of both solitary cells and metastases in whole mouse liver by magnetic resonance imaging
-
Townson, J.L. et al. Three-dimensional imaging and quantification of both solitary cells and metastases in whole mouse liver by magnetic resonance imaging. Cancer Res. 69, 8326-8331 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 8326-8331
-
-
Townson, J.L.1
-
180
-
-
0347504928
-
Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases
-
Naumov, G.N. et al. Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases. Breast Cancer Res. Treat. 82, 199-206 (2003).
-
(2003)
Breast Cancer Res. Treat.
, vol.82
, pp. 199-206
-
-
Naumov, G.N.1
-
181
-
-
77954538586
-
An autoimmune-mediated strategy for prophylactic breast cancer vaccination
-
Jaini, R. et al. An autoimmune-mediated strategy for prophylactic breast cancer vaccination. Nat. Med. 16, 799-803 (2010).
-
(2010)
Nat. Med.
, vol.16
, pp. 799-803
-
-
Jaini, R.1
-
182
-
-
42649100970
-
Clinical relevance and specific biological properties of disseminating tumour cells
-
Pantel, K., Brakenhoff, R.H. & Brandt, B. Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nat. Rev. Cancer 8, 329-340 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 329-340
-
-
Pantel, K.1
Brakenhoff, R.H.2
Detection, B.B.3
-
183
-
-
24744450378
-
Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: Updated findings from NCIC CTG MA.17
-
Goss, P.E. et al. Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17. J. Natl. Cancer Inst. 97, 1262-1271 (2005).
-
(2005)
J. Natl. Cancer Inst.
, vol.97
, pp. 1262-1271
-
-
Goss, P.E.1
-
184
-
-
33947265272
-
TEACH:Tykerb evaluation after chemotherapy
-
Moy, B. & Goss, P.E. TEACH: Tykerb evaluation after chemotherapy. Clin. Breast Cancer 7, 489-492 (2007).
-
(2007)
Clin. Breast Cancer
, vol.7
, pp. 489-492
-
-
Moy, B.1
Goss, P.E.2
-
185
-
-
73949118717
-
Sensitivity to the aromatase inhibitor letrozole is prolonged after a break"in treatment
-
Sabnis, G., Goloubeva, O., Gilani, R., Macedo, L. & Brodie, A. Sensitivity to the aromatase inhibitor letrozole is prolonged after a "break" in treatment. Mol. Cancer Ther. 9, 46-56 (2010).
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 46-56
-
-
Sabnis, G.1
Goloubeva, O.2
Gilani, R.3
MacEdo, L.4
Brodie, A.5
-
186
-
-
73949092851
-
Randomized, double-blind trial of carboplatin and paclitaxel with either daily oral cediranib or placebo in advanced non-small-cell lung cancer: NCIC clinical trials group BR24 study
-
Goss, G.D. et al. Randomized, double-blind trial of carboplatin and paclitaxel with either daily oral cediranib or placebo in advanced non-small-cell lung cancer: NCIC clinical trials group BR24 study. J. Clin. Oncol. 28, 49-55 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 49-55
-
-
Goss, G.D.1
-
187
-
-
84859403854
-
Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: A randomized trial
-
Alberts, S.R. et al. Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: a randomized trial. J. Am. Med. Assoc. 307, 1383-1393 (2012).
-
(2012)
J. Am. Med. Assoc.
, vol.307
, pp. 1383-1393
-
-
Alberts, S.R.1
-
188
-
-
60649116477
-
Silencing or fueling metastasis with VEGF inhibitors: Antiangiogenesis revisited
-
Loges, S., Mazzone, M., Hohensinner, P. & Carmeliet, P. Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited. Cancer Cell 15, 167-170 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 167-170
-
-
Loges, S.1
Mazzone, M.2
Hohensinner, P.3
Carmeliet, P.4
-
189
-
-
84875183611
-
Metastasis awakening: The challenges of targeting minimal residual cancer
-
Polzer, B. & Klein, C.A. Metastasis awakening: the challenges of targeting minimal residual cancer. Nat. Med. 19, 274-275 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 274-275
-
-
Polzer, B.1
Klein, C.A.2
-
190
-
-
47949114668
-
Detection of mutations in EGFR in circulating lung-cancer cells
-
Maheswaran, S. et al. Detection of mutations in EGFR in circulating lung-cancer cells. N. Engl. J. Med. 359, 366-377 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 366-377
-
-
Maheswaran, S.1
-
191
-
-
82355170196
-
Quantitative high-resolution genomic analysis of single cancer cells
-
Hannemann, J. et al. Quantitative high-resolution genomic analysis of single cancer cells. PLoS ONE 6, e26362 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Hannemann, J.1
-
192
-
-
67649311599
-
Latent bone metastasis in breast cancer tied to Src-dependent survival signals
-
Zhang, X.H. et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell 16, 67-78 (2009).
-
(2009)
Cancer Cell
, vol.16
, pp. 67-78
-
-
Zhang, X.H.1
-
193
-
-
84862917865
-
Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone
-
Kobayashi, A. et al. Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone. J. Exp. Med. 208, 2641-2655 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2641-2655
-
-
Kobayashi, A.1
-
194
-
-
84866061054
-
Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer
-
Marshall, J.C. et al. Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer. J. Natl. Cancer Inst. 104, 1306-1319 (2012).
-
(2012)
J. Natl. Cancer Inst.
, vol.104
, pp. 1306-1319
-
-
Marshall, J.C.1
-
195
-
-
37549041384
-
Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2
-
Horak, C.E. et al. Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2. Cancer Res. 67, 11751-11759 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 11751-11759
-
-
Horak, C.E.1
-
196
-
-
52049118079
-
The role of metastasis suppressor genes in metastatic dormancy
-
Horak, C.E., Lee, J.H., Marshall, J.C., Shreeve, S.M. & Steeg, P.S. The role of metastasis suppressor genes in metastatic dormancy. APMIS 116, 586-601 (2008).
-
(2008)
APMIS
, vol.116
, pp. 586-601
-
-
Horak, C.E.1
Lee, J.H.2
Marshall, J.C.3
Shreeve, S.M.4
Steeg, P.S.5
-
197
-
-
79952069716
-
Thinking outside the box: Using metastasis suppressors as molecular tools
-
Thiolloy, S. & Rinker-Schaeffer, C.W. Thinking outside the box: using metastasis suppressors as molecular tools. Semin. Cancer Biol. 21, 89-98 (2011).
-
(2011)
Semin. Cancer Biol.
, vol.21
, pp. 89-98
-
-
Thiolloy, S.1
Rinker-Schaeffer, C.W.2
-
198
-
-
79952072718
-
Metastasis suppressors and the tumor microenvironment
-
Cook, L.M., Hurst, D.R. & Welch, D.R. Metastasis suppressors and the tumor microenvironment. Semin. Cancer Biol. 21, 113-122 (2011).
-
(2011)
Semin. Cancer Biol.
, vol.21
, pp. 113-122
-
-
Cook, L.M.1
Hurst, D.R.2
Welch, D.R.3
-
199
-
-
72849140888
-
Bisphosphonates in the prevention of disease recurrence: Current results and ongoing trials
-
Gnant, M. Bisphosphonates in the prevention of disease recurrence: current results and ongoing trials. Curr. Cancer Drug Targets 9, 824-833 (2009).
-
(2009)
Curr. Cancer Drug Targets
, vol.9
, pp. 824-833
-
-
Gnant, M.1
-
200
-
-
78650397541
-
Clinical development of anti-RANKL therapies for treatment and prevention of bone metastasis
-
Lipton, A. & Goessl, C. Clinical development of anti-RANKL therapies for treatment and prevention of bone metastasis. Bone 48, 96-99 (2011).
-
(2011)
Bone
, vol.48
, pp. 96-99
-
-
Lipton, A.1
Goessl, C.2
-
201
-
-
79959774035
-
Denosumab an option for patients with bone metastasis from breast cancer
-
Barton, M.K. Denosumab an option for patients with bone metastasis from breast cancer. CA Cancer J. Clin. 61, 135-136 (2011).
-
(2011)
CA Cancer J. Clin.
, vol.61
, pp. 135-136
-
-
Barton, M.K.1
-
202
-
-
84856454999
-
TGF-b in the bone microenvironment: Role in breast cancer metastases
-
Buijs, J.T., Stayrook, K.R. & Guise, T.A. TGF-b in the bone microenvironment: role in breast cancer metastases. Cancer Microenviron. 4, 261-281 (2011).
-
(2011)
Cancer Microenviron
, vol.4
, pp. 261-281
-
-
Buijs, J.T.1
Stayrook, K.R.2
Guise, T.A.3
-
203
-
-
84871611946
-
Clinical opportunities and challenges in targeting tumour dormancy
-
Hensel, J.A., Flaig, T.W. & Theodorescu, D. Clinical opportunities and challenges in targeting tumour dormancy. Nat. Rev. Clin. Oncol. 10, 41-51 (2013).
-
(2013)
Nat. Rev. Clin. Oncol.
, vol.10
, pp. 41-51
-
-
Hensel, J.A.1
Flaig, T.W.2
Theodorescu, D.3
-
204
-
-
79961087495
-
Controversies in clinical cancer dormancy
-
Uhr, J.W. & Pantel, K. Controversies in clinical cancer dormancy. Proc. Natl. Acad. Sci. USA 108, 12396-12400 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 12396-12400
-
-
Uhr, J.W.1
Pantel, K.2
-
205
-
-
52049107370
-
Tumor dormancy and immunoescape
-
Quesnel, B. Tumor dormancy and immunoescape. APMIS 116, 685-694 (2008).
-
(2008)
APMIS
, vol.116
, pp. 685-694
-
-
Quesnel, B.1
-
206
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff, P.W. et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N. Engl. J. Med. 363, 411-422 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
-
207
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi, F.S. et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363, 711-723 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
-
208
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert, C. et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N. Engl. J. Med. 364, 2517-2526 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
-
210
-
-
20944450851
-
Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases
-
discussion
-
Pawlik, T.M. et al. Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases. Ann. Surg. 241, 715-722, discussion 722-714 (2005).
-
(2005)
Ann. Surg.
, vol.241
, Issue.715-722
, pp. 722-714
-
-
Pawlik, T.M.1
-
211
-
-
84870945783
-
Oligo-and polymetastatic progression in lung metastasis(es) patients is associated with specific microRNAs
-
erratum 7 e50141 (2012). 212
-
Lussier, Y.A. et al. Oligo-and polymetastatic progression in lung metastasis(es) patients is associated with specific microRNAs. PLoS ONE 7, e50141 (2012); erratum 7, e50141 (2012). 212
-
(2012)
PLoS ONE
, vol.7
-
-
Lussier, Y.A.1
-
212
-
-
84881020480
-
Tracking tumor resistance using 'liquid biopsies
-
Pantel K.,Diaz, L.A.Jr. & Polyak, K. Tracking tumor resistance using 'liquid biopsies'. Nat. Med. 19, 676-677 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 676-677
-
-
Pantel, K.1
Diaz Jr., L.A.2
Polyak, K.3
-
213
-
-
66449095667
-
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis
-
Valastyan, S. et al. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 137, 1032-1046 (2009).
-
(2009)
Cell
, vol.137
, pp. 1032-1046
-
-
Valastyan, S.1
-
214
-
-
66349121917
-
Adaptive therapy
-
Gatenby, R.A., Silva, A.S., Gillies, R.J. & Frieden, B.R. Adaptive therapy. Cancer Res. 69, 4894-4903 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 4894-4903
-
-
Gatenby, R.A.1
Silva, A.S.2
Gillies, R.J.3
Frieden, B.R.4
-
215
-
-
84873728334
-
Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance
-
Das Thakur, M. et al. Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance. Nature 494, 251-255 (2013).
-
(2013)
Nature
, vol.494
, pp. 251-255
-
-
Das Thakur, M.1
-
216
-
-
53749103325
-
Intermittent androgen blockade should be regarded as standard therapy in prostate cancer
-
Seruga, B. & Tannock, I.F. Intermittent androgen blockade should be
-
(2008)
Nat. Clin. Pract. Oncol.
, vol.5
, pp. 574-576
-
-
Seruga, B.1
Tannock, I.F.2
-
217
-
-
84878728191
-
Intermittent versus continuous androgen deprivation therapy in advanced prostate cancer
-
Klotz, L. Intermittent versus continuous androgen deprivation therapy in advanced prostate cancer. Curr. Urol. Rep. 14, 159-167 (2013).
-
(2013)
Curr. Urol. Rep.
, vol.14
, pp. 159-167
-
-
Klotz, L.1
-
218
-
-
77955172181
-
Metronomic chemotherapy: New rationale fornew directions
-
Pasquier, E., Kavallaris, M. & Andre, N. Metronomic chemotherapy: new rationale for new directions. Nat. Rev. Clin. Oncol. 7, 455-465 (2010).
-
(2010)
Nat. Rev. Clin. Oncol.
, vol.7
, pp. 455-465
-
-
Pasquier, E.1
Kavallaris, M.2
Andre, N.3
-
219
-
-
0034048358
-
Less is more, regularly: Metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
-
Hanahan, D., Bergers, G. & Bergsland, E. Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J. Clin. Invest. 105, 1045-1047 (2000).
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1045-1047
-
-
Hanahan, D.1
Bergers, G.2
Bergsland, E.3
-
220
-
-
63049090100
-
Metastasis: From dissemination to organ-specific colonization
-
Nguyen, D.X., Bos, P.D. & Massague, J. Metastasis: from dissemination to organ-specific colonization. Nat. Rev. Cancer 9, 274-284 (2009).
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 274-284
-
-
Nguyen, D.X.1
Bos, P.D.2
Massague, J.3
-
221
-
-
0036161957
-
Epidemiology of unknown primary tumours; Incidence and population-based survival of 1285 patients in Southeast Netherlands 1984-1992
-
van de Wouw, A.J., Janssen-Heijnen, M.L., Coebergh, J.W. & Hillen, H.F. Epidemiology of unknown primary tumours; incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984-1992. Eur. J. Cancer 38, 409-413 (2002).
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 409-413
-
-
Van De Wouw, A.J.1
Janssen-Heijnen, M.L.2
Coebergh, J.W.3
Hillen, H.F.4
-
222
-
-
84883375246
-
Capture of viable circulating tumor cells in the liver of colorectal cancer patients
-
Denève, E. et al. Capture of viable circulating tumor cells in the liver of colorectal cancer patients. Clin. Chem. 59, 1384-1392 (2013).
-
(2013)
Clin. Chem.
, vol.59
, pp. 1384-1392
-
-
Denève, E.1
-
223
-
-
84989656720
-
Metastatic inefficiency: The scientific basis for resection of liver metastases from colorectal cancer
-
Sugarbaker, P.H. Metastatic inefficiency: the scientific basis for resection of liver metastases from colorectal cancer. J. Surg. Oncol. Suppl. 3, 158-160 (1993).
-
(1993)
J. Surg. Oncol. Suppl.
, vol.3
, pp. 158-160
-
-
Sugarbaker, P.H.1
-
224
-
-
0028885643
-
Individual development and uPA-receptor expression of dissemi nated tumour cells in bone marrow: A reference to early systemic disease in solid cancer
-
Heiss, M.M. et al. Individual development and uPA-receptor expression of dissemi nated tumour cells in bone marrow: a reference to early systemic disease in solid cancer. Nat. Med. 1, 1035-1039 (1995).
-
(1995)
Nat. Med.
, vol.1
, pp. 1035-1039
-
-
Heiss, M.M.1
-
225
-
-
84877579861
-
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
-
Murtaza, M. et al. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature 497, 108-112 (2013).
-
(2013)
Nature
, vol.497
, pp. 108-112
-
-
Murtaza, M.1
-
226
-
-
84875520648
-
Analysis of circulating tumor DNA to monitor metastatic breast cancer
-
Dawson, S.J. et al. Analysis of circulating tumor DNA to monitor metastatic breast cancer. N. Engl. J. Med. 368, 1199-1209 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1199-1209
-
-
Dawson, S.J.1
-
227
-
-
84863100828
-
Considerations in the development of circulating tumor cell technology for clinical use
-
Parkinson, D.R. et al. Considerations in the development of circulating tumor cell technology for clinical use. J. Transl. Med. 10, 138 (2012).
-
(2012)
J. Transl. Med.
, vol.10
, pp. 138
-
-
Parkinson, D.R.1
-
228
-
-
84868204665
-
Clinical usefulness of bone markers in prostate cancer with bone metastasis
-
Kamiya, N. et al. Clinical usefulness of bone markers in prostate cancer with bone metastasis. Int. J. Urol. 19, 968-979 (2012).
-
(2012)
Int. J. Urol.
, vol.19
, pp. 968-979
-
-
Kamiya, N.1
-
229
-
-
84887459210
-
Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis
-
in the press
-
Ell, B. et al. Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis. Cancer Cell (in the press).
-
Cancer Cell
-
-
Ell, B.1
-
230
-
-
84872176550
-
Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease
-
Kwong, G.A. et al. Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease. Nat. Biotechnol. 31, 63-70 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 63-70
-
-
Kwong, G.A.1
-
231
-
-
57849100048
-
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
-
Erler, J.T. et al. Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell 15, 35-44 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 35-44
-
-
Erler, J.T.1
-
232
-
-
84859994398
-
Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer
-
Kim, R.S. et al. Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer. PLoS ONE 7, e35569 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Kim, R.S.1
-
233
-
-
20244376908
-
Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development
-
Kelloff, G.J. et al. Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development. Clin. Cancer Res. 11, 2785-2808 (2005).
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 2785-2808
-
-
Kelloff, G.J.1
-
234
-
-
84882272075
-
In vivo imaging of glucose uptake and metabolism in tumors
-
Walker-Samuel, S. et al. In vivo imaging of glucose uptake and metabolism in tumors. Nat. Med. 19, 1067-1072 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 1067-1072
-
-
Walker-Samuel, S.1
-
235
-
-
34248646775
-
Imaging oxygenation of human tumours
-
Padhani, A.R., Krohn, K.A., Lewis, J.S. & Alber, M. Imaging oxygenation of human tumours. Eur. Radiol. 17, 861-872 (2007).
-
(2007)
Eur. Radiol.
, vol.17
, pp. 861-872
-
-
Padhani, A.R.1
Krohn, K.A.2
Lewis, J.S.3
Alber, M.4
-
236
-
-
33846168055
-
Targeted in vivo imaging of angiogenesis: Present status and perspectives
-
Choe, Y.S. & Lee, K.H. Targeted in vivo imaging of angiogenesis: present status and perspectives. Curr. Pharm. Des. 13, 17-31 (2007).
-
(2007)
Curr. Pharm. Des.
, vol.13
, pp. 17-31
-
-
Choe, Y.S.1
Lee, K.H.2
-
237
-
-
84883760198
-
Vessel architectural imaging identifies cancer patient responders to anti-angiogenic therapy
-
Emblem, K.E. et al. Vessel architectural imaging identifies cancer patient responders to anti-angiogenic therapy. Nat. Med. 19, 1178-1183 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 1178-1183
-
-
Emblem, K.E.1
-
238
-
-
80455129848
-
18F-FDG PET/CT for monitoring treatment responses to the epidermal growth factor receptor inhibitor erlotinib
-
Benz, M.R. et al. 18F-FDG PET/CT for monitoring treatment responses to the epidermal growth factor receptor inhibitor erlotinib. J. Nucl. Med. 52, 1684-1689 (2011).
-
(2011)
J. Nucl. Med.
, vol.52
, pp. 1684-1689
-
-
Benz, M.R.1
-
239
-
-
33745108827
-
Tumor targeting by an aptamer
-
Hicke B.J.,et al.Tumor targeting by an aptamer. J. Nucl. Med. 47, 668-678 (2006).
-
(2006)
J. Nucl. Med.
, vol.47
, pp. 668-678
-
-
Hicke, B.J.1
|