-
1
-
-
84867133601
-
Genetic and epigenetic contribution to complex traits
-
Kilpinen H, Dermitzakis ET.Genetic and epigenetic contribution to complex traits.Hum Mol Genet.2012;21:R24-8.
-
(2012)
Hum Mol Genet
, vol.21
, pp. R24-R28
-
-
Kilpinen, H.1
Dermitzakis, E.T.2
-
2
-
-
84859174608
-
Histone-modifying enzymes:regulators of developmental decisions and drivers of human disease
-
Butler JS, Koutelou E, Schibler AC, Dent SY.Histone-modifying enzymes:regulators of developmental decisions and drivers of human disease.Epigenomics.2012;4:163-77.
-
(2012)
Epigenomics
, vol.4
, pp. 163-177
-
-
Butler, J.S.1
Koutelou, E.2
Schibler, A.C.3
Dent, S.Y.4
-
3
-
-
84890774986
-
Genetic and epigenetic factors in etiology of diabetes mellitus type 1
-
Stankov K, Benc D, Draskovic D.Genetic and epigenetic factors in etiology of diabetes mellitus type 1.Pediatrics.2013;132:1112-22.
-
(2013)
Pediatrics
, vol.132
, pp. 1112-1122
-
-
Stankov, K.1
Benc, D.2
Draskovic, D.3
-
4
-
-
84919839650
-
Clinical applications of epigenetics in cardiovascular disease:the long road ahead
-
Aslibekyan S, Claas SA, Arnett DK.Clinical applications of epigenetics in cardiovascular disease:the long road ahead.Transl Res.2014.doi:10.1016/j.trsl.2014.04.004.
-
(2014)
Transl Res
-
-
Aslibekyan, S.1
Claas, S.A.2
Arnett, D.K.3
-
7
-
-
84899760651
-
MicroRNAs and post-transcriptional regulation of skeletal development
-
Gamez B, Rodriguez-Carballo E, Ventura F.MicroRNAs and post-transcriptional regulation of skeletal development.J Mol Endocrinol.2014;52:R179-97.
-
(2014)
J Mol Endocrinol
, vol.52
, pp. R179-R197
-
-
Gamez, B.1
Rodriguez-Carballo, E.2
Ventura, F.3
-
9
-
-
84895917052
-
Epigenetic mechanisms and non-coding RNAs in osteoarthritis
-
Barter MJ, Young DA.Epigenetic mechanisms and non-coding RNAs in osteoarthritis.Curr Rheumatol Rep.2013;15:353.
-
(2013)
Curr Rheumatol Rep
, vol.15
, pp. 353
-
-
Barter, M.J.1
Young, D.A.2
-
10
-
-
77957339220
-
Interplay between different epigenetic modifications and mechanisms
-
Murr R.Interplay between different epigenetic modifications and mechanisms.Adv Genet.2010;70:101-41.
-
(2010)
Adv Genet
, vol.70
, pp. 101-141
-
-
Murr, R.1
-
11
-
-
84907904739
-
MicroRNAs in the skeleton:cell-restricted or potent intercellular communicators?
-
van der Eerden BC.MicroRNAs in the skeleton:cell-restricted or potent intercellular communicators? Arch Biochem Biophys.2014 doi:10.1016/j.abb.2014.04.016.
-
(2014)
Arch Biochem Biophys
-
-
van der Eerden, B.C.1
-
14
-
-
84857978205
-
Mechanisms in endocrinology:micro-RNAs:targets for enhancing osteoblast differentiation and bone formation
-
Taipaleenmaki H, Bjerre Hokland L, Chen L, Kauppinen S, Kassem M.Mechanisms in endocrinology:micro-RNAs:targets for enhancing osteoblast differentiation and bone formation.Eur J Endocrinol.2012;166:359-71.
-
(2012)
Eur J Endocrinol
, vol.166
, pp. 359-371
-
-
Taipaleenmaki, H.1
Bjerre Hokland, L.2
Chen, L.3
Kauppinen, S.4
Kassem, M.5
-
16
-
-
84863621527
-
Cancer epigenetics:from mechanism to therapy
-
DawsonMA, Kouzarides T.Cancer epigenetics:from mechanism to therapy.Cell.2012;150:12-27.
-
(2012)
Cell
, vol.150
, pp. 12-27
-
-
Dawson, M.A.1
Kouzarides, T.2
-
17
-
-
84886860116
-
TET enzymes, TDG and the dynamics of DNA demethylation
-
Kohli RM, Zhang Y.TET enzymes, TDG and the dynamics of DNA demethylation.Nature.2013;502:472-9.
-
(2013)
Nature
, vol.502
, pp. 472-479
-
-
Kohli, R.M.1
Zhang, Y.2
-
18
-
-
84902253414
-
Aberrant DNA, methylation of microRNA genes in human breast cancer-a critical appraisal
-
Lehmann U.Aberrant DNA, methylation of microRNA genes in human breast cancer-a critical appraisal.Cell Tissue Res.2014;356:657-64.
-
(2014)
Cell Tissue Res
, vol.356
, pp. 657-664
-
-
Lehmann, U.1
-
19
-
-
77951974552
-
DNA methylation mediated by a microRNA pathway
-
Wu L, Zhou H, Zhang Q, et al.DNA methylation mediated by a microRNA pathway.Mol Cell.2010;38:465-75.
-
(2010)
Mol Cell
, vol.38
, pp. 465-475
-
-
Wu, L.1
Zhou, H.2
Zhang, Q.3
-
20
-
-
84873818150
-
Epigenetic regulation during fetal femur development:DNA methylation matters
-
de Andres MC, Kingham E, Imagawa K, et al.Epigenetic regulation during fetal femur development:DNA methylation matters.PLoS One.2013;8:e54957.
-
(2013)
PLoS One
, vol.8
-
-
de Andres, M.C.1
Kingham, E.2
Imagawa, K.3
-
21
-
-
0036197327
-
Reduced CpG methylation is associated with transcriptional activation of the bonespecific rat osteocalcin gene in osteoblasts
-
Villagra A, Gutierrez J, Paredes R, et al.Reduced CpG methylation is associated with transcriptional activation of the bonespecific rat osteocalcin gene in osteoblasts.J Cell Biochem.2002;85:112-22.
-
(2002)
J Cell Biochem
, vol.85
, pp. 112-122
-
-
Villagra, A.1
Gutierrez, J.2
Paredes, R.3
-
22
-
-
33847689862
-
Methylation of the mouse DIx5 and Osx gene promoters regulates cell type-specific gene expression
-
Lee JY, Lee YM, Kim MJ, et al.Methylation of the mouse DIx5 and Osx gene promoters regulates cell type-specific gene expression.Mol Cells.2006;22:182-8.
-
(2006)
Mol Cells
, vol.22
, pp. 182-188
-
-
Lee, J.Y.1
Lee, Y.M.2
Kim, M.J.3
-
23
-
-
84908090536
-
The regulatory landscape of osteogenic differentiation
-
Hakelien AM, Bryne JC, Harstad KG, et al.The regulatory landscape of osteogenic differentiation.Stem Cells.2014;32:2780-93.
-
(2014)
Stem Cells
, vol.32
, pp. 2780-2793
-
-
Hakelien, A.M.1
Bryne, J.C.2
Harstad, K.G.3
-
24
-
-
84887490574
-
Dexamethasone shifts bonemarrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation
-
Li J, Zhang N, HuangX, et al.Dexamethasone shifts bonemarrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation.Cell Death Dis.2013;4:e832.
-
(2013)
Cell Death Dis
, vol.4
-
-
Li, J.1
Zhang, N.2
Huang, X.3
-
25
-
-
8544284075
-
Enzymes involved in the activation and inactivation of vitamin D
-
Prosser DE, Jones G.Enzymes involved in the activation and inactivation of vitamin D.Trends Biochem Sci.2004;29:664-73.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 664-673
-
-
Prosser, D.E.1
Jones, G.2
-
27
-
-
84906789954
-
DNA methylation levels of CYP2R1 and CYP24A1 predict vitamin D response variation
-
Zhou Y, Zhao LJ, Xu X, et al.DNA methylation levels of CYP2R1 and CYP24A1 predict vitamin D response variation.J Steroid Biochem Mol Biol.2014;144PA:207-14.
-
(2014)
J Steroid Biochem Mol Biol
, vol.144 PA
, pp. 207-214
-
-
Zhou, Y.1
Zhao, L.J.2
Xu, X.3
-
28
-
-
84904647822
-
DNA methyltransferases:a novel target for prevention and therapy
-
Subramaniam D, Thombre R, Dhar A, Anant S.DNA methyltransferases:a novel target for prevention and therapy.Front Oncol.2014;4:80.
-
(2014)
Front Oncol
, vol.4
, pp. 80
-
-
Subramaniam, D.1
Thombre, R.2
Dhar, A.3
Anant, S.4
-
29
-
-
84895155334
-
Epigenetics in 2013.DNA methylation and miRNA-key roles in systemic autoimmunity
-
Richardson BC, Patel DR.Epigenetics in 2013.DNA methylation and miRNA-key roles in systemic autoimmunity.Nat Rev Rheumatol.2014;10:72-4.
-
(2014)
Nat Rev Rheumatol
, vol.10
, pp. 72-74
-
-
Richardson, B.C.1
Patel, D.R.2
-
30
-
-
84908381697
-
Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage
-
Jeffries MA, Donica M, Baker L, et al.Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.Arthritis Rheumatol.2014.doi:10.1002/art.38762.
-
(2014)
Arthritis Rheumatol
-
-
Jeffries, M.A.1
Donica, M.2
Baker, L.3
-
31
-
-
84871770976
-
Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis
-
Delgado-Calle J, Fernandez AF, Sainz J, et al.Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis.Arthritis Rheum.2013;65:197-205.
-
(2013)
Arthritis Rheum
, vol.65
, pp. 197-205
-
-
Delgado-Calle, J.1
Fernandez, A.F.2
Sainz, J.3
-
32
-
-
84859433312
-
Epigenetic mechanisms in cartilage and osteoarthritis:DNA methylation, histone modifications and microRNAs
-
BarterMJ, Bui C, Young DA.Epigenetic mechanisms in cartilage and osteoarthritis:DNA methylation, histone modifications and microRNAs.Osteoarthritis Cartilage.2012;20:339-49.
-
(2012)
Osteoarthritis Cartilage
, vol.20
, pp. 339-349
-
-
Barter, M.J.1
Bui, C.2
Young, D.A.3
-
33
-
-
84875999020
-
Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1beta (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites
-
Hashimoto K, Otero M, Imagawa K, et al.Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1beta (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.J Biol Chem.2013;288:10061-72.
-
(2013)
J Biol Chem
, vol.288
, pp. 10061-10072
-
-
Hashimoto, K.1
Otero, M.2
Imagawa, K.3
-
34
-
-
84924253904
-
Reduced type IX collagen gene expression in human osteoarthritic chondrocytes is associated with epigenetic silencing by DNA hypermethylation
-
Imagawa K, de Andres MC, Hashimoto K, et al.Reduced type IX collagen gene expression in human osteoarthritic chondrocytes is associated with epigenetic silencing by DNA hypermethylation.Arthritis Rheumatol.2014.doi:10.1002/art.38774.
-
(2014)
Arthritis Rheumatol
-
-
Imagawa, K.1
de Andres, M.C.2
Hashimoto, K.3
-
35
-
-
79952539053
-
ATP-dependent chromatin remodeling:genetics, genomics and mechanisms
-
Hargreaves DC, Crabtree GR.ATP-dependent chromatin remodeling:genetics, genomics and mechanisms.Cell Res.2011;21:396-420.
-
(2011)
Cell Res
, vol.21
, pp. 396-420
-
-
Hargreaves, D.C.1
Crabtree, G.R.2
-
36
-
-
34248201771
-
Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter
-
Gutierrez J, Paredes R, Cruzat F, et al.Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter.J Biol Chem.2007;282:9445-57.
-
(2007)
J Biol Chem
, vol.282
, pp. 9445-9457
-
-
Gutierrez, J.1
Paredes, R.2
Cruzat, F.3
-
37
-
-
0029883812
-
Changes in chromatin structure support constitutive and developmentally regulated transcription of the bone-specific osteocalcin gene in osteoblastic cells
-
Montecino M, Lian J, Stein G, Stein J.Changes in chromatin structure support constitutive and developmentally regulated transcription of the bone-specific osteocalcin gene in osteoblastic cells.Biochemistry.1996;35:5093-102.
-
(1996)
Biochemistry
, vol.35
, pp. 5093-5102
-
-
Montecino, M.1
Lian, J.2
Stein, G.3
Stein, J.4
-
38
-
-
84880864749
-
Histone modifications for human epigenome analysis
-
Kimura H.Histone modifications for human epigenome analysis.J Hum Genet.2013;58:439-45.
-
(2013)
J Hum Genet
, vol.58
, pp. 439-445
-
-
Kimura, H.1
-
39
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein BE, Mikkelsen TS, Xie X, et al.A bivalent chromatin structure marks key developmental genes in embryonic stem cells.Cell.2006;125:315-26.
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
-
40
-
-
84863633423
-
Histone demethylases KDM4B and KDM6B promotes osteogenic differentiation of human MSCs
-
Ye L, Fan Z, Yu B, et al.Histone demethylases KDM4B and KDM6B promotes osteogenic differentiation of human MSCs.Cell Stem Cell.2012;11:50-61.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 50-61
-
-
Ye, L.1
Fan, Z.2
Yu, B.3
-
41
-
-
8344261349
-
Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis
-
Vega RB, Matsuda K, Oh J, et al.Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis.Cell.2004;119:555-66.
-
(2004)
Cell
, vol.119
, pp. 555-566
-
-
Vega, R.B.1
Matsuda, K.2
Oh, J.3
-
42
-
-
77955349977
-
Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat
-
Razidlo DF,Whitney TJ, Casper ME, et al.Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat.PLoS One.2010;5:e11492.
-
(2010)
PLoS One
, vol.5
-
-
Razidlo, D.F.1
Whitney, T.J.2
Casper, M.E.3
-
43
-
-
84881173297
-
Histone deacetylation mediates the rejuvenation of osteoblastogenesis by the combination of 25(OH)D3 and parathyroid hormone in MSCs from elders
-
Zhou S, Geng S, Glowacki J.Histone deacetylation mediates the rejuvenation of osteoblastogenesis by the combination of 25(OH)D3 and parathyroid hormone in MSCs from elders.J Steroid Biochem Mol Biol.2013;136:156-9.
-
(2013)
J Steroid Biochem Mol Biol
, vol.136
, pp. 156-159
-
-
Zhou, S.1
Geng, S.2
Glowacki, J.3
-
44
-
-
84872481094
-
Histone deacetylase inhibitor trichostatin A promotes the osteogenic differentiation of rat adipose-derived stem cells by altering the epigenetic modifications on Runx2 promoter in a BMP signaling-dependent manner
-
Hu X, Zhang X, Dai L, et al.Histone deacetylase inhibitor trichostatin A promotes the osteogenic differentiation of rat adipose-derived stem cells by altering the epigenetic modifications on Runx2 promoter in a BMP signaling-dependent manner.Stem Cells Dev.2013;22:248-55.
-
(2013)
Stem Cells Dev
, vol.22
, pp. 248-255
-
-
Hu, X.1
Zhang, X.2
Dai, L.3
-
46
-
-
43149106504
-
Wdr5 is essential for osteoblast differentiation
-
Zhu ED, Demay MB, Gori F.Wdr5 is essential for osteoblast differentiation.J Biol Chem.2008;283:7361-7.
-
(2008)
J Biol Chem
, vol.283
, pp. 7361-7367
-
-
Zhu, E.D.1
Demay, M.B.2
Gori, F.3
-
47
-
-
75649143350
-
Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase
-
Sinha KM, Yasuda H, Coombes MM, Dent SY, de Crombrugghe B.Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase.EMBO J.2010;29:68-79.
-
(2010)
EMBO J
, vol.29
, pp. 68-79
-
-
Sinha, K.M.1
Yasuda, H.2
Coombes, M.M.3
Dent, S.Y.4
de Crombrugghe, B.5
-
48
-
-
84894262774
-
EZH2 and KDM6A act as an epigenetic switch to regulate mesenchymal stem cell lineage specification
-
Hemming S, Cakouros D, Isenmann S, et al.EZH2 and KDM6A act as an epigenetic switch to regulate mesenchymal stem cell lineage specification.Stem Cells.2014;32:802-15.
-
(2014)
Stem Cells
, vol.32
, pp. 802-815
-
-
Hemming, S.1
Cakouros, D.2
Isenmann, S.3
-
49
-
-
21744432518
-
SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation
-
Young DW, Pratap J, Javed A, et al.SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation.J Cell Biochem.2005;94:720-30.
-
(2005)
J Cell Biochem
, vol.94
, pp. 720-730
-
-
Young, D.W.1
Pratap, J.2
Javed, A.3
-
50
-
-
68049109194
-
SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2
-
Cruzat F, Henriquez B, Villagra A, et al.SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.Biochemistry.2009;48:7287-95.
-
(2009)
Biochemistry
, vol.48
, pp. 7287-7295
-
-
Cruzat, F.1
Henriquez, B.2
Villagra, A.3
-
51
-
-
34948835315
-
Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes:contributions of the DNA sequence
-
Montecino M, Stein JL, SteinGS, et al.Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes:contributions of the DNA sequence.Biochem Cell Biol.2007;85:419-25.
-
(2007)
Biochem Cell Biol
, vol.85
, pp. 419-425
-
-
Montecino, M.1
Stein, J.L.2
Stein, G.S.3
-
52
-
-
84899633354
-
Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis
-
Identified Runx2 binding to genomic DNA that discovered hundreds of Runx2 target genes related to epigenetic levels of control during stages of osteoblast differentiation.The complete data set serve as a valuable resource for investigators
-
Wu H, Whitfield TW, Gordon JA, et al.Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis.Genome Biol.2014;15:R52.Identified Runx2 binding to genomic DNA that discovered hundreds of Runx2 target genes related to epigenetic levels of control during stages of osteoblast differentiation.The complete data set serve as a valuable resource for investigators.
-
(2014)
Genome Biol
, vol.15
-
-
Wu, H.1
Whitfield, T.W.2
Gordon, J.A.3
-
53
-
-
84865757142
-
Landscape of transcription in human cells
-
Djebali S, Davis CA, Merkel A, et al.Landscape of transcription in human cells.Nature.2012;489:101-8.
-
(2012)
Nature
, vol.489
, pp. 101-108
-
-
Djebali, S.1
Davis, C.A.2
Merkel, A.3
-
54
-
-
84887101163
-
MicroRNAs and other non-coding RNAs as targets for anticancer drug development
-
Ling H, Fabbri M, Calin GA.MicroRNAs and other non-coding RNAs as targets for anticancer drug development.Nat Rev Drug Discov.2013;12:847-65.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 847-865
-
-
Ling, H.1
Fabbri, M.2
Calin, G.A.3
-
55
-
-
84897128298
-
The noncoding RNA revolution-trashing old rules to forge new ones
-
Cech TR, Steitz JA.The noncoding RNA revolution-trashing old rules to forge new ones.Cell.2014;157:77-94.
-
(2014)
Cell
, vol.157
, pp. 77-94
-
-
Cech, T.R.1
Steitz, J.A.2
-
56
-
-
84902141800
-
Long noncoding RNAs in cell-fate programming and reprogramming
-
Flynn RA, Chang HY.Long noncoding RNAs in cell-fate programming and reprogramming.Cell Stem Cell.2014;14:752-61.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 752-761
-
-
Flynn, R.A.1
Chang, H.Y.2
-
57
-
-
84904985459
-
Regulation of microRNA biogenesis
-
Ha M, Kim VN.Regulation of microRNA biogenesis.Nat Rev Mol Cell Biol.2014;15:509-24.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 509-524
-
-
Ha, M.1
Kim, V.N.2
-
58
-
-
84904735424
-
Transcriptional regulatory functions of nuclear long noncoding RNAs
-
Vance KW, Ponting CP.Transcriptional regulatory functions of nuclear long noncoding RNAs.Trends Genet.2014;30:348-55.
-
(2014)
Trends Genet
, vol.30
, pp. 348-355
-
-
Vance, K.W.1
Ponting, C.P.2
-
59
-
-
84884220048
-
Long noncoding RNAs usher in a new era in the biology of enhancers
-
Orom UA, Shiekhattar R.Long noncoding RNAs usher in a new era in the biology of enhancers.Cell.2013;154:1190-3.
-
(2013)
Cell
, vol.154
, pp. 1190-1193
-
-
Orom, U.A.1
Shiekhattar, R.2
-
60
-
-
84875177348
-
X-inactivation, imprinting, and long noncoding RNAs in health and disease
-
Lee JT, Bartolomei MS.X-inactivation, imprinting, and long noncoding RNAs in health and disease.Cell.2013;152:1308-23.
-
(2013)
Cell
, vol.152
, pp. 1308-1323
-
-
Lee, J.T.1
Bartolomei, M.S.2
-
61
-
-
84904272774
-
Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer
-
Paci P, Colombo T, Farina L.Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer.BMCSyst Biol.2014;8:83.
-
(2014)
BMCSyst Biol
, vol.8
, pp. 83
-
-
Paci, P.1
Colombo, T.2
Farina, L.3
-
62
-
-
84875496875
-
Downregulated LncRNA-ANCR promotes osteoblast differentiation by targeting EZH2 and regulating Runx2 expression
-
Zhu L, Xu PC.Downregulated LncRNA-ANCR promotes osteoblast differentiation by targeting EZH2 and regulating Runx2 expression.Biochem Biophys Res Commun.2013;432:612-7.
-
(2013)
Biochem Biophys Res Commun
, vol.432
, pp. 612-617
-
-
Zhu, L.1
Xu, P.C.2
-
63
-
-
84896812260
-
The H19 long noncoding RNA gives rise to microRNAs miR-675-3p and miR-675-5p to promote skeletal muscle differentiation and regeneration
-
Dey BK, Pfeifer K, Dutta A.The H19 long noncoding RNA gives rise to microRNAs miR-675-3p and miR-675-5p to promote skeletal muscle differentiation and regeneration.Genes Dev.2014;28:491-501.
-
(2014)
Genes Dev
, vol.28
, pp. 491-501
-
-
Dey, B.K.1
Pfeifer, K.2
Dutta, A.3
-
64
-
-
84885740857
-
Targeted disruption of Hotair leads to homeotic transformation and gene derepression
-
Li L, Liu B, Wapinski OL, et al.Targeted disruption of Hotair leads to homeotic transformation and gene derepression.Cell Rep.2013;5:3-12.
-
(2013)
Cell Rep
, vol.5
, pp. 3-12
-
-
Li, L.1
Liu, B.2
Wapinski, O.L.3
-
65
-
-
84885806535
-
Long noncoding RNAs in development:solidifying the Lncs to Hox gene regulation
-
Dasen JS.Long noncoding RNAs in development:solidifying the Lncs to Hox gene regulation.Cell Rep.2013;5:1-2.
-
(2013)
Cell Rep
, vol.5
, pp. 1-2
-
-
Dasen, J.S.1
-
66
-
-
33846489816
-
Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2
-
Young DW, Hassan MQ, Pratap J, et al.Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.Nature.2007;445:442-6.
-
(2007)
Nature
, vol.445
, pp. 442-446
-
-
Young, D.W.1
Hassan, M.Q.2
Pratap, J.3
-
67
-
-
84892924886
-
Bookmarking target genes in mitosis:a shared epigenetic trait of phenotypic transcription factors and oncogenes?
-
Zaidi SK, Grandy RA, Lopez-Camacho C, et al.Bookmarking target genes in mitosis:a shared epigenetic trait of phenotypic transcription factors and oncogenes? Cancer Res.2014;74:420-5.
-
(2014)
Cancer Res
, vol.74
, pp. 420-425
-
-
Zaidi, S.K.1
Grandy, R.A.2
Lopez-Camacho, C.3
-
69
-
-
34249334327
-
Nuclear microenvironments in biological control and cancer
-
Zaidi SK, Young DW, Javed A, et al.Nuclear microenvironments in biological control and cancer.Nat Rev Cancer.2007;7:454-63.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 454-463
-
-
Zaidi, S.K.1
Young, D.W.2
Javed, A.3
-
71
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM.MicroRNA signatures in human cancers.Nat Rev Cancer.2006;6:857-66.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
72
-
-
84905852282
-
The microRNA-23b/27b/24 cluster promotes breast cancer lung metastasis by targeting metastasissuppressive gene prosaposin
-
Ell B, Qiu Q, Wei Y, et al.The microRNA-23b/27b/24 cluster promotes breast cancer lung metastasis by targeting metastasissuppressive gene prosaposin.J Biol Chem.2014;289:21888-95.
-
(2014)
J Biol Chem
, vol.289
, pp. 21888-21895
-
-
Ell, B.1
Qiu, Q.2
Wei, Y.3
-
73
-
-
84901840628
-
MicroRNAs in the control of metastatic bone disease
-
Browne G, Taipaleenmaki H, Stein GS, Stein JL, Lian JB.MicroRNAs in the control of metastatic bone disease.Trends Endocrinol Metab.2014;25:320-7.
-
(2014)
Trends Endocrinol Metab
, vol.25
, pp. 320-327
-
-
Browne, G.1
Taipaleenmaki, H.2
Stein, G.S.3
Stein, J.L.4
Lian, J.B.5
-
74
-
-
84904801055
-
MicroRNAs and bone metastasis:a new challenge
-
Croset M, Santini D, Iuliani M, et al.MicroRNAs and bone metastasis:a new challenge.Molecules.2014;19:10115-28.
-
(2014)
Molecules
, vol.19
, pp. 10115-10128
-
-
Croset, M.1
Santini, D.2
Iuliani, M.3
-
75
-
-
84878404863
-
MicroRNAs in osteosarcoma:from biological players to clinical contributors, a review
-
Zhou G, Shi X, Zhang J, Wu S, Zhao J.MicroRNAs in osteosarcoma:from biological players to clinical contributors, a review.J Int Med Res.2013;41:1-12.
-
(2013)
J Int Med Res
, vol.41
, pp. 1-12
-
-
Zhou, G.1
Shi, X.2
Zhang, J.3
Wu, S.4
Zhao, J.5
-
76
-
-
84903648308
-
MicroRNA:important player in the pathobiology of multiple myeloma
-
Bi C, ChngWJ.MicroRNA:important player in the pathobiology of multiple myeloma.Biomed Res Int.2014;2014:521586.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 521586
-
-
Bi, C.1
Chng, W.J.2
-
77
-
-
77649187445
-
Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse
-
Gaur T, Hussain S, Mudhasani R, et al.Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse.Dev Biol.2010;340:10-21.
-
(2010)
Dev Biol
, vol.340
, pp. 10-21
-
-
Gaur, T.1
Hussain, S.2
Mudhasani, R.3
-
78
-
-
84871345038
-
miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells
-
Hassan MQ, Maeda Y, Taipaleenmaki H, et al.miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells.J Biol Chem.2012;287:42084-92.
-
(2012)
J Biol Chem
, vol.287
, pp. 42084-42092
-
-
Hassan, M.Q.1
Maeda, Y.2
Taipaleenmaki, H.3
-
79
-
-
79960633240
-
Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1
-
Zhang J, Tu Q, Bonewald LF, et al.Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1.J Bone Miner Res.2011;26:1953-63.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 1953-1963
-
-
Zhang, J.1
Tu, Q.2
Bonewald, L.F.3
-
80
-
-
84903470443
-
MicroRNA-338-3p regulates osteogenic differentiation of mouse bone marrow stromal stem cells by targeting Runx2 and Fgfr2
-
Liu H, Sun Q,Wan C, Li L, Zhang L, Chen Z.MicroRNA-338-3p regulates osteogenic differentiation of mouse bone marrow stromal stem cells by targeting Runx2 and Fgfr2.J Cell Physiol.2014;229:1494-502.
-
(2014)
J Cell Physiol
, vol.229
, pp. 1494-1502
-
-
Liu, H.1
Sun, Q.2
Wan, C.3
Li, L.4
Zhang, L.5
Chen, Z.6
-
81
-
-
79960015376
-
A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2
-
Zhang Y, Xie RL, Croce CM, et al.A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2.Proc Natl Acad Sci U S A.2011;108:9863-8.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 9863-9868
-
-
Zhang, Y.1
Xie, R.L.2
Croce, C.M.3
-
82
-
-
85027948268
-
MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31
-
Baglio SR, Devescovi V, Granchi D, Baldini N.MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31.Gene.2013;527:321-31.
-
(2013)
Gene
, vol.527
, pp. 321-331
-
-
Baglio, S.R.1
Devescovi, V.2
Granchi, D.3
Baldini, N.4
-
83
-
-
84883487422
-
miR-145 suppresses osteogenic differentiation by targeting Sp7
-
Jia J, Tian Q, Ling S, Liu Y, Yang S, Shao Z.miR-145 suppresses osteogenic differentiation by targeting Sp7.FEBS Lett.2013;587:3027-31.
-
(2013)
FEBS Lett
, vol.587
, pp. 3027-3031
-
-
Jia, J.1
Tian, Q.2
Ling, S.3
Liu, Y.4
Yang, S.5
Shao, Z.6
-
84
-
-
84898923321
-
MiR-143 suppresses osteogenic differentiation by targeting Osterix
-
Li E, Zhang J, Yuan T, Ma B.MiR-143 suppresses osteogenic differentiation by targeting Osterix.Mol Cell Biochem.2014;390:69-74.
-
(2014)
Mol Cell Biochem
, vol.390
, pp. 69-74
-
-
Li, E.1
Zhang, J.2
Yuan, T.3
Ma, B.4
-
85
-
-
84874623866
-
Identification and characterization of microRNAs controlled by the osteoblast-specific transcription factor Osterix
-
Chen Q, Liu W, Sinha KM, Yasuda H, de Crombrugghe B.Identification and characterization of microRNAs controlled by the osteoblast-specific transcription factor Osterix.PLoS One.2013;8:e58104.
-
(2013)
PLoS One
, vol.8
-
-
Chen, Q.1
Liu, W.2
Sinha, K.M.3
Yasuda, H.4
de Crombrugghe, B.5
-
86
-
-
84872094361
-
miR-214 targets ATF4 to inhibit bone formation
-
Demonstrated the therapeutic effectiveness of antagomiR delivery to osteoblasts in vivo to prevent bone loss in mouse models of osteoporosis
-
Wang X, Guo B, Li Q, et al.miR-214 targets ATF4 to inhibit bone formation.Nat Med.2013;19:93-100.Demonstrated the therapeutic effectiveness of antagomiR delivery to osteoblasts in vivo to prevent bone loss in mouse models of osteoporosis.
-
(2013)
Nat Med
, vol.19
, pp. 93-100
-
-
Wang, X.1
Guo, B.2
Li, Q.3
-
87
-
-
84879462457
-
The role of miR-31-modified adipose tissue-derived stem cells in repairing rat critical-sized calvarial defects
-
Deng Y, Zhou H, Zou D, et al.The role of miR-31-modified adipose tissue-derived stem cells in repairing rat critical-sized calvarial defects.Biomaterials.2013;34:6717-28.
-
(2013)
Biomaterials
, vol.34
, pp. 6717-6728
-
-
Deng, Y.1
Zhou, H.2
Zou, D.3
-
88
-
-
78650548873
-
A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program
-
Hassan MQ, Gordon JA, BelotiMM, et al.A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program.Proc Natl Acad Sci U S A.2010;107:19879-84.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 19879-19884
-
-
Hassan, M.Q.1
Gordon, J.A.2
Beloti, M.M.3
-
89
-
-
67650169908
-
Biological functions of miR- 29b contribute to positive regulation of osteoblast differentiation
-
Li Z, Hassan MQ, Jafferji M, et al.Biological functions of miR- 29b contribute to positive regulation of osteoblast differentiation.J Biol Chem.2009;284:15676-84.
-
(2009)
J Biol Chem
, vol.284
, pp. 15676-15684
-
-
Li, Z.1
Hassan, M.Q.2
Jafferji, M.3
-
90
-
-
79953686494
-
A microRNA expression signature of osteoclastogenesis
-
Sugatani T, Vacher J, Hruska KA.A microRNA expression signature of osteoclastogenesis.Blood.2011;117:3648-57.
-
(2011)
Blood
, vol.117
, pp. 3648-3657
-
-
Sugatani, T.1
Vacher, J.2
Hruska, K.A.3
-
91
-
-
82155163802
-
MicroRNA biogenesis and regulation of bone remodeling
-
Kapinas K, Delany AM.MicroRNA biogenesis and regulation of bone remodeling.Arthritis Res Ther.2011;13:220.
-
(2011)
Arthritis Res Ther
, vol.13
, pp. 220
-
-
Kapinas, K.1
Delany, A.M.2
-
92
-
-
52949114558
-
A microRNA signature for a BMP2-induced osteoblast lineage commitment program
-
Li Z, Hassan MQ, Volinia S, et al.A microRNA signature for a BMP2-induced osteoblast lineage commitment program.Proc Natl Acad Sci U S A.2008;105:13906-11.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13906-13911
-
-
Li, Z.1
Hassan, M.Q.2
Volinia, S.3
-
93
-
-
78649974535
-
Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism
-
Wang J, Greene SB, Bonilla-Claudio M, et al.Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism.Dev Cell.2010;19:903-12.
-
(2010)
Dev Cell
, vol.19
, pp. 903-912
-
-
Wang, J.1
Greene, S.B.2
Bonilla-Claudio, M.3
-
94
-
-
84892823844
-
Osteoblast-adipocyte lineage plasticity in tissue development, maintenance and pathology
-
Berendsen AD, Olsen BR.Osteoblast-adipocyte lineage plasticity in tissue development, maintenance and pathology.Cell Mol Life Sci.2014;71:493-7.
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 493-497
-
-
Berendsen, A.D.1
Olsen, B.R.2
-
95
-
-
84866325660
-
New insights into osteoporosis:the bone-fat connection
-
Kawai M, de Paula FJ, Rosen CJ.New insights into osteoporosis:the bone-fat connection.J Intern Med.2012;272:317-29.
-
(2012)
J Intern Med
, vol.272
, pp. 317-329
-
-
Kawai, M.1
de Paula, F.J.2
Rosen, C.J.3
-
96
-
-
84876928351
-
Redundant miR-3077-5p and miR- 705 mediate the shift of mesenchymal stem cell lineage commitment to adipocyte in osteoporosis bone marrow
-
Liao L, Yang X, Su X, et al.Redundant miR-3077-5p and miR- 705 mediate the shift of mesenchymal stem cell lineage commitment to adipocyte in osteoporosis bone marrow.Cell Death Dis.2013;4:e600.
-
(2013)
Cell Death Dis
, vol.4
-
-
Liao, L.1
Yang, X.2
Su, X.3
-
97
-
-
84864281323
-
Upregulation ofmiR-22 promotes osteogenic differentiation and inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells by repressing HDAC6 protein expression
-
Huang S,Wang S, Bian C, et al.Upregulation ofmiR-22 promotes osteogenic differentiation and inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells by repressing HDAC6 protein expression.Stem Cells Dev.2012;21:2531-40.
-
(2012)
Stem Cells Dev
, vol.21
, pp. 2531-2540
-
-
Huang, S.1
Wang, S.2
Bian, C.3
-
98
-
-
77149136767
-
MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation
-
Huang J, Zhao L, Xing L, Chen D.MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation.Stem Cells.2010;28:357-64.
-
(2010)
Stem Cells
, vol.28
, pp. 357-364
-
-
Huang, J.1
Zhao, L.2
Xing, L.3
Chen, D.4
-
99
-
-
84877892009
-
MicroRNA-322 (miR-322) and its target protein Tob2 modulate Osterix (Osx) mRNA stability
-
Gamez B, Rodriguez-Carballo E, Bartrons R, Rosa JL, Ventura F.MicroRNA-322 (miR-322) and its target protein Tob2 modulate Osterix (Osx) mRNA stability.J Biol Chem.2013;288:14264-75.
-
(2013)
J Biol Chem
, vol.288
, pp. 14264-14275
-
-
Gamez, B.1
Rodriguez-Carballo, E.2
Bartrons, R.3
Rosa, J.L.4
Ventura, F.5
-
100
-
-
84862487811
-
miR-93/Sp7 function loop mediates osteoblast mineralization
-
Yang L, Cheng P, Chen C, et al.miR-93/Sp7 function loop mediates osteoblast mineralization.J Bone Miner Res.2012;27:1598-606.
-
(2012)
J Bone Miner Res
, vol.27
, pp. 1598-1606
-
-
Yang, L.1
Cheng, P.2
Chen, C.3
-
101
-
-
84901218175
-
A positive role of microRNA-15b on regulation of osteoblast differentiation
-
Vimalraj S, Partridge NC, Selvamurugan N.A positive role of microRNA-15b on regulation of osteoblast differentiation.J Cell Physiol.2014;229:1236-44.
-
(2014)
J Cell Physiol
, vol.229
, pp. 1236-1244
-
-
Vimalraj, S.1
Partridge, N.C.2
Selvamurugan, N.3
-
103
-
-
84864383515
-
Intronic microRNAs:a crossroad in gene regulation
-
Gromak N.Intronic microRNAs:a crossroad in gene regulation.Biochem Soc Trans.2012;40:759-61.
-
(2012)
Biochem Soc Trans
, vol.40
, pp. 759-761
-
-
Gromak, N.1
-
104
-
-
84872527492
-
Genome-wide epigenetic regulation of miRNAs in cancer
-
Baer C, Claus R, Plass C.Genome-wide epigenetic regulation of miRNAs in cancer.Cancer Res.2013;73:473-7.
-
(2013)
Cancer Res
, vol.73
, pp. 473-477
-
-
Baer, C.1
Claus, R.2
Plass, C.3
-
105
-
-
72849121740
-
A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans
-
Li H, Xie H, Liu W, et al.A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans.J Clin Invest.2009;119:3666-77.
-
(2009)
J Clin Invest
, vol.119
, pp. 3666-3677
-
-
Li, H.1
Xie, H.2
Liu, W.3
-
106
-
-
78650946447
-
Polymorphisms in predicted miRNA binding sites and osteoporosis
-
Lei SF, Papasian CJ, Deng HW.Polymorphisms in predicted miRNA binding sites and osteoporosis.J Bone Miner Res.2011;26:72-8.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 72-78
-
-
Lei, S.F.1
Papasian, C.J.2
Deng, H.W.3
-
107
-
-
34247608645
-
HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes
-
HassanMQ, Tare R, Lee SH, et al.HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes.Mol Cell Biol.2007;27:3337-52.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3337-3352
-
-
Hassan, M.Q.1
Tare, R.2
Lee, S.H.3
-
108
-
-
77954353828
-
Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors
-
Gordon JA, HassanMQ, Saini S, et al.Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors.Mol Cell Biol.2010;30:3531-41.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 3531-3541
-
-
Gordon, J.A.1
Hassan, M.Q.2
Saini, S.3
-
109
-
-
84892719952
-
MiR-503 regulates osteoclastogenesis via targeting RANK
-
Chen C, Cheng P, Xie H, et al.MiR-503 regulates osteoclastogenesis via targeting RANK.J Bone Miner Res.2014;29:338-47.
-
(2014)
J Bone Miner Res
, vol.29
, pp. 338-347
-
-
Chen, C.1
Cheng, P.2
Xie, H.3
-
110
-
-
84859595006
-
MiR-133a in human circulating monocytes:a potential biomarker associated with postmenopausal osteoporosis
-
Wang Y, Li L, Moore BT, et al.MiR-133a in human circulating monocytes:a potential biomarker associated with postmenopausal osteoporosis.PLoS One.2012;7:e34641.
-
(2012)
PLoS One
, vol.7
-
-
Wang, Y.1
Li, L.2
Moore, B.T.3
-
111
-
-
84901226648
-
Five freely circulating miRNAs and bone tissue miRNAs are associated with osteoporotic fractures
-
Seeliger C, Karpinski K, Haug AT, et al.Five freely circulating miRNAs and bone tissue miRNAs are associated with osteoporotic fractures.J Bone Miner Res.2014;29:1718-28.
-
(2014)
J Bone Miner Res
, vol.29
, pp. 1718-1728
-
-
Seeliger, C.1
Karpinski, K.2
Haug, A.T.3
-
112
-
-
84876261835
-
Down-regulation of miR-21 biogenesis by estrogen action contributes to osteoclastic apoptosis
-
Sugatani T, Hruska KA.Down-regulation of miR-21 biogenesis by estrogen action contributes to osteoclastic apoptosis.J Cell Biochem.2013;114:1217-22.
-
(2013)
J Cell Biochem
, vol.114
, pp. 1217-1222
-
-
Sugatani, T.1
Hruska, K.A.2
-
113
-
-
84885368280
-
Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis
-
First study highlights the translational potential of miRNAs associated with osteoclasts to inhibit metastatic bone disease by systemic delivery in mouse models of tumor growth in bone
-
Ell B, Mercatali L, Ibrahim T, et al.Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis.Cancer Cell.2013;24:542-56.First study highlights the translational potential of miRNAs associated with osteoclasts to inhibit metastatic bone disease by systemic delivery in mouse models of tumor growth in bone.
-
(2013)
Cancer Cell
, vol.24
, pp. 542-556
-
-
Ell, B.1
Mercatali, L.2
Ibrahim, T.3
-
114
-
-
84907406375
-
miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2
-
Krzeszinski JY, Wei W, Huynh H, et al.miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.Nature.2014;512:431-5.
-
(2014)
Nature
, vol.512
, pp. 431-435
-
-
Krzeszinski, J.Y.1
Wei, W.2
Huynh, H.3
-
115
-
-
84896690540
-
Osteosarcoma treatment- where do we stand? A state of the art review
-
Luetke A, Meyers PA, Lewis I, Juergens H.Osteosarcoma treatment- where do we stand? A state of the art review.Cancer Treat Rev.2014;40:523-32.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 523-532
-
-
Luetke, A.1
Meyers, P.A.2
Lewis, I.3
Juergens, H.4
-
116
-
-
84908009459
-
Advances in targeted therapy for osteosarcoma
-
Zhou W, Hao M, Du X, Chen K, Wang G, Yang J.Advances in targeted therapy for osteosarcoma.Discov Med.2014;17:301-7.
-
(2014)
Discov Med
, vol.17
, pp. 301-307
-
-
Zhou, W.1
Hao, M.2
Du, X.3
Chen, K.4
Wang, G.5
Yang, J.6
-
117
-
-
84896696942
-
Cells of origin in osteosarcoma:mesenchymal stem cells or osteoblast committed cells?
-
Mutsaers AJ,Walkley CR.Cells of origin in osteosarcoma:mesenchymal stem cells or osteoblast committed cells? Bone.2014;62:56-63.
-
(2014)
Bone
, vol.62
, pp. 56-63
-
-
Mutsaers, A.J.1
Walkley, C.R.2
-
119
-
-
84897574602
-
CXCR4 antibody treatment suppresses metastatic spread to the lung of intratibial human osteosarcoma xenografts in mice
-
Brennecke P, Arlt MJ, Campanile C, et al.CXCR4 antibody treatment suppresses metastatic spread to the lung of intratibial human osteosarcoma xenografts in mice.Clin Exp Metastasis.2014;31:339-49.
-
(2014)
Clin Exp Metastasis
, vol.31
, pp. 339-349
-
-
Brennecke, P.1
Arlt, M.J.2
Campanile, C.3
-
120
-
-
79251553733
-
The Role of RUNX2 in Osteosarcoma Oncogenesis
-
Martin JW, ZielenskaM, Stein GS, vanWijnen AJ, Squire JA.The Role of RUNX2 in Osteosarcoma Oncogenesis.Sarcoma.2011;2011:282745.
-
(2011)
Sarcoma
, vol.2011
, pp. 282745
-
-
Martin, J.W.1
Zielenska, M.2
Stein, G.S.3
vanWijnen, A.J.4
Squire, J.A.5
-
121
-
-
77952065237
-
Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy
-
Sadikovic B, Thorner P, Chilton-Macneill S, et al.Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy.BMC Cancer.2010;10:202.
-
(2010)
BMC Cancer
, vol.10
, pp. 202
-
-
Sadikovic, B.1
Thorner, P.2
Chilton-Macneill, S.3
-
122
-
-
84863139254
-
Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility
-
van der Deen M, Akech J, Lapointe D, et al.Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.J Biol Chem.2012;287:4503-17.
-
(2012)
J Biol Chem
, vol.287
, pp. 4503-4517
-
-
van der Deen, M.1
Akech, J.2
Lapointe, D.3
-
123
-
-
70449727683
-
Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1)
-
Pereira BP, Zhou Y, Gupta A, et al.Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).J Cell Physiol.2009;221:778-88.
-
(2009)
J Cell Physiol
, vol.221
, pp. 778-788
-
-
Pereira, B.P.1
Zhou, Y.2
Gupta, A.3
-
124
-
-
84889982620
-
Correlation of WWOX, RUNX2 and VEGFA protein expression in human osteosarcoma
-
Yang J, Zhao L, Tian W, et al.Correlation of WWOX, RUNX2 and VEGFA protein expression in human osteosarcoma.BMC Med Genomics.2013;6:56.
-
(2013)
BMC Med Genomics
, vol.6
, pp. 56
-
-
Yang, J.1
Zhao, L.2
Tian, W.3
-
125
-
-
84855690496
-
Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma
-
DelMare S, Kurek KC, Stein GS, Lian JB, Aqeilan RI.Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma.Am J Cancer Res.2011;1:585-94.
-
(2011)
Am J Cancer Res
, vol.1
, pp. 585-594
-
-
DelMare, S.1
Kurek, K.C.2
Stein, G.S.3
Lian, J.B.4
Aqeilan, R.I.5
-
126
-
-
77954367818
-
Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression
-
Kurek KC, Del Mare S, Salah Z, et al.Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression.Cancer Res.2010;70:5577-86.
-
(2010)
Cancer Res
, vol.70
, pp. 5577-5586
-
-
Kurek, K.C.1
Del Mare, S.2
Salah, Z.3
-
127
-
-
52049102904
-
The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism
-
Aqeilan RI, Hassan MQ, de Bruin A, et al.The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism.J Biol Chem.2008;283:21629-39.
-
(2008)
J Biol Chem
, vol.283
, pp. 21629-21639
-
-
Aqeilan, R.I.1
Hassan, M.Q.2
de Bruin, A.3
-
128
-
-
84881472377
-
MicroRNAs in osteosarcoma:diagnostic and therapeutic aspects
-
Miao J, Wu S, Peng Z, Tania M, Zhang C.MicroRNAs in osteosarcoma:diagnostic and therapeutic aspects.Tumor Biol.2013;34:2093-8.
-
(2013)
Tumor Biol
, vol.34
, pp. 2093-2098
-
-
Miao, J.1
Wu, S.2
Peng, Z.3
Tania, M.4
Zhang, C.5
-
129
-
-
84878780637
-
The miRNAs in the pathogenesis of osteosarcoma
-
Liang W, Gao B, Fu P, Xu S, Qian Y, Fu Q.The miRNAs in the pathogenesis of osteosarcoma.Front Biosci (Landmark Ed).2013;18:788-94.
-
(2013)
Front Biosci (Landmark Ed)
, vol.18
, pp. 788-794
-
-
Liang, W.1
Gao, B.2
Fu, P.3
Xu, S.4
Qian, Y.5
Fu, Q.6
-
130
-
-
84859386766
-
miRNA signatures associate with pathogenesis and progression of osteosarcoma
-
Jones KB, Salah Z, Del Mare S, et al.miRNA signatures associate with pathogenesis and progression of osteosarcoma.Cancer Res.2012;72:1865-77.
-
(2012)
Cancer Res
, vol.72
, pp. 1865-1877
-
-
Jones, K.B.1
Salah, Z.2
Del Mare, S.3
-
131
-
-
79960673180
-
Analysis of miRNA-gene expressiongenomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma
-
Maire G, Martin JW, Yoshimoto M, Chilton-MacNeill S, Zielenska M, Squire JA.Analysis of miRNA-gene expressiongenomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma.Cancer Genet.2011;204:138-46.
-
(2011)
Cancer Genet
, vol.204
, pp. 138-146
-
-
Maire, G.1
Martin, J.W.2
Yoshimoto, M.3
Chilton-MacNeill, S.4
Zielenska, M.5
Squire, J.A.6
-
132
-
-
84871452751
-
A three-plasma miRNA signature serves as novel biomarkers for osteosarcoma
-
Ouyang L, Liu P, Yang S, Ye S, Xu W, Liu X.A three-plasma miRNA signature serves as novel biomarkers for osteosarcoma.Med Oncol.2013;30:340.
-
(2013)
Med Oncol
, vol.30
, pp. 340
-
-
Ouyang, L.1
Liu, P.2
Yang, S.3
Ye, S.4
Xu, W.5
Liu, X.6
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