메뉴 건너뛰기




Volumn 5 APR, Issue , 2014, Pages

Vitamin D and the epigenome

Author keywords

1,25 dihydroxyvitamin D3; CpG island; CYP24A1; CYP27B1; DNA methylation; Histone modifications; VDR; VDRE

Indexed keywords

25 HYDROXYERGOCALCIFEROL; CALCIDIOL 1 MONOOXYGENASE; DNA; DNA METHYLTRANSFERASE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEMETHYLASE; HISTONE METHYLTRANSFERASE; SECALCIFEROL; VITAMIN D; VITAMIN D RECEPTOR;

EID: 84901014703     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2014.00164     Document Type: Review
Times cited : (222)

References (159)
  • 3
    • 79651473285 scopus 로고    scopus 로고
    • Vitamin D receptor gene methylation is associated with ethnicity, tuberculosis, and TaqI polymorphism
    • doi: 10.1016/j.humimm.2010.12.010
    • Andraos, C., Koorsen, G., Knight, J. C., and Bornman, L. (2011). Vitamin D receptor gene methylation is associated with ethnicity, tuberculosis, and TaqI polymorphism. Hum. Immunol. 72, 262-268. doi: 10.1016/j.humimm.2010.12.010
    • (2011) Hum. Immunol. , vol.72 , pp. 262-268
    • Andraos, C.1    Koorsen, G.2    Knight, J.C.3    Bornman, L.4
  • 4
    • 54949104629 scopus 로고    scopus 로고
    • A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis
    • doi: 10.4161/epi.3.4.6508
    • Arasaradnam, R. P., Commane, D. M., Bradburn, D., and Mathers, J. C. (2008). A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis. Epigenetics 3, 193-198. doi: 10.4161/epi.3.4.6508
    • (2008) Epigenetics , vol.3 , pp. 193-198
    • Arasaradnam, R.P.1    Commane, D.M.2    Bradburn, D.3    Mathers, J.C.4
  • 5
    • 24744453331 scopus 로고    scopus 로고
    • Methyl-CpG-binding proteins in cancer: blaming the DNA methylation messenger
    • doi: 10.1139/o05-035
    • Ballestar, E., and Esteller, M. (2005). Methyl-CpG-binding proteins in cancer: blaming the DNA methylation messenger. Biochem. Cell Biol. 83, 374-384. doi: 10.1139/o05-035
    • (2005) Biochem. Cell Biol. , vol.83 , pp. 374-384
    • Ballestar, E.1    Esteller, M.2
  • 6
    • 33846933274 scopus 로고    scopus 로고
    • Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
    • doi: 10.1038/nature05515
    • Barreto, G., Schafer, A., Marhold, J., Stach, D., Swaminathan, S. K., Handa, V., et al. (2007). Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 445, 671-675. doi: 10.1038/nature05515
    • (2007) Nature , vol.445 , pp. 671-675
    • Barreto, G.1    Schafer, A.2    Marhold, J.3    Stach, D.4    Swaminathan, S.K.5    Handa, V.6
  • 7
    • 80053144962 scopus 로고    scopus 로고
    • A decade of exploring the cancer epigenome - biological and translational implications
    • doi: 10.1038/nrc3130
    • Baylin, S. B., and Jones, P. A. (2011). A decade of exploring the cancer epigenome - biological and translational implications. Nat. Rev. Cancer 11, 726-734. doi: 10.1038/nrc3130
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 726-734
    • Baylin, S.B.1    Jones, P.A.2
  • 8
    • 23744461983 scopus 로고    scopus 로고
    • Transposons reanimated in mice
    • doi: 10.1016/j.cell.2005.07.024
    • Bestor, T. H. (2005). Transposons reanimated in mice. Cell 122, 322-325. doi: 10.1016/j.cell.2005.07.024
    • (2005) Cell , vol.122 , pp. 322-325
    • Bestor, T.H.1
  • 9
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • doi: 10.1101/gad.947102
    • Bird, A. (2002). DNA methylation patterns and epigenetic memory. Genes Dev. 16, 6-21. doi: 10.1101/gad.947102
    • (2002) Genes Dev. , vol.16 , pp. 6-21
    • Bird, A.1
  • 10
    • 0019322245 scopus 로고
    • DNA methylation and the frequency of CpG in animal DNA
    • doi: 10.1093/nar/8.7.1499
    • Bird, A. P. (1980). DNA methylation and the frequency of CpG in animal DNA. Nucleic Acids Res. 8, 1499-1504. doi: 10.1093/nar/8.7.1499
    • (1980) Nucleic Acids Res. , vol.8 , pp. 1499-1504
    • Bird, A.P.1
  • 11
    • 34548131197 scopus 로고    scopus 로고
    • Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors
    • doi: 10.1093/jnci/djm069
    • Bjornsson, H. T., Brown, L. J., Fallin, M. D., Rongione, M. A., Bibikova, M., Wickham, E., et al. (2007). Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors. J. Natl. Cancer Inst. 99, 1270-1273. doi: 10.1093/jnci/djm069
    • (2007) J. Natl. Cancer Inst. , vol.99 , pp. 1270-1273
    • Bjornsson, H.T.1    Brown, L.J.2    Fallin, M.D.3    Rongione, M.A.4    Bibikova, M.5    Wickham, E.6
  • 12
    • 53849136271 scopus 로고    scopus 로고
    • Vitamin D and human health: lessons from vitamin D receptor null mice
    • doi: 10.1210/er.2008-0004
    • Bouillon, R., Carmeliet, G., Verlinden, L., Van Etten, E., Verstuyf, A., Luderer, H. F., et al. (2008). Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr. Rev. 29, 726-776. doi: 10.1210/er.2008-0004
    • (2008) Endocr. Rev. , vol.29 , pp. 726-776
    • Bouillon, R.1    Carmeliet, G.2    Verlinden, L.3    Van Etten, E.4    Verstuyf, A.5    Luderer, H.F.6
  • 13
    • 84855985851 scopus 로고    scopus 로고
    • Expression and function of the vitamin D receptor in malignant germ cell tumour of the testis
    • Bremmer, F., Thelen, P., Pottek, T., Behnes, C. L., Radzun, H. J., and Schweyer, S. (2012). Expression and function of the vitamin D receptor in malignant germ cell tumour of the testis. Anticancer Res. 32, 341-349.
    • (2012) Anticancer Res. , vol.32 , pp. 341-349
    • Bremmer, F.1    Thelen, P.2    Pottek, T.3    Behnes, C.L.4    Radzun, H.J.5    Schweyer, S.6
  • 14
    • 40849124009 scopus 로고    scopus 로고
    • DNA methylation markers and early recurrence in stage I lung cancer
    • doi: 10.1056/NEJMoa0706550
    • Brock, M. V., Hooker, C. M., Ota-Machida, E., Han, Y., Guo, M., Ames, S., et al. (2008). DNA methylation markers and early recurrence in stage I lung cancer. N. Engl. J. Med. 358, 1118-1128. doi: 10.1056/NEJMoa0706550
    • (2008) N. Engl. J. Med. , vol.358 , pp. 1118-1128
    • Brock, M.V.1    Hooker, C.M.2    Ota-Machida, E.3    Han, Y.4    Guo, M.5    Ames, S.6
  • 15
    • 0034455926 scopus 로고    scopus 로고
    • Reduced parathyroid vitamin D receptor messenger ribonucleic acid levels in primary and secondary hyperparathyroidism
    • doi: 10.1210/jc.85.5.2000
    • Carling, T., Rastad, J., Szabó, E., Westin, G., and Akerström, G. (2000). Reduced parathyroid vitamin D receptor messenger ribonucleic acid levels in primary and secondary hyperparathyroidism. J. Clin. Endocrinol. Metab. 85, 2000-2003. doi: 10.1210/jc.85.5.2000
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 2000-2003
    • Carling, T.1    Rastad, J.2    Szabó, E.3    Westin, G.4    Akerström, G.5
  • 16
    • 84875677701 scopus 로고    scopus 로고
    • VDR hypermethylation and HIV-induced T cell loss
    • doi: 10.1189/jlb.0812383
    • Chandel, N., Husain, M., Goel, H., Salhan, D., Lan, X., Malhotra, A., et al. (2013). VDR hypermethylation and HIV-induced T cell loss. J. Leukoc. Biol. 93, 623-631. doi: 10.1189/jlb.0812383
    • (2013) J. Leukoc. Biol. , vol.93 , pp. 623-631
    • Chandel, N.1    Husain, M.2    Goel, H.3    Salhan, D.4    Lan, X.5    Malhotra, A.6
  • 17
    • 0035676731 scopus 로고    scopus 로고
    • Expression profile of histone deacetylase 1 in gastric cancer tissues
    • doi: 10.1111/j.1349-7006.2001.tb02153.x
    • Choi, J. H., Kwon, H. J., Yoon, B. I., Kim, J. H., Han, S. U., Joo, H. J., et al. (2001). Expression profile of histone deacetylase 1 in gastric cancer tissues. Jpn. J. Cancer Res. 92, 1300-1304. doi: 10.1111/j.1349-7006.2001.tb02153.x
    • (2001) Jpn. J. Cancer Res. , vol.92 , pp. 1300-1304
    • Choi, J.H.1    Kwon, H.J.2    Yoon, B.I.3    Kim, J.H.4    Han, S.U.5    Joo, H.J.6
  • 18
    • 33947245128 scopus 로고    scopus 로고
    • RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3
    • doi: 10.1016/j.cell.2007.02.003
    • Christensen, J., Agger, K., Cloos, P. A., Pasini, D., Rose, S., Sennels, L., et al. (2007). RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3. Cell 128, 1063-1076. doi: 10.1016/j.cell.2007.02.003
    • (2007) Cell , vol.128 , pp. 1063-1076
    • Christensen, J.1    Agger, K.2    Cloos, P.A.3    Pasini, D.4    Rose, S.5    Sennels, L.6
  • 19
    • 33746332412 scopus 로고    scopus 로고
    • The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
    • doi: 10.1038/nature04837
    • Cloos, P. A., Christensen, J., Agger, K., Maiolica, A., Rappsilber, J., Antal, T., et al. (2006). The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. Nature 442, 307-311. doi: 10.1038/nature04837
    • (2006) Nature , vol.442 , pp. 307-311
    • Cloos, P.A.1    Christensen, J.2    Agger, K.3    Maiolica, A.4    Rappsilber, J.5    Antal, T.6
  • 20
    • 0037436509 scopus 로고    scopus 로고
    • Loss of IGF2 imprinting: a potential marker of colorectal cancer risk
    • doi: 10.1126/science.1080902
    • Cui, H., Cruz-Correa, M., Giardiello, F. M., Hutcheon, D. F., Kafonek, D. R., Brandenburg, S., et al. (2003). Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science 299, 1753-1755. doi: 10.1126/science.1080902
    • (2003) Science , vol.299 , pp. 1753-1755
    • Cui, H.1    Cruz-Correa, M.2    Giardiello, F.M.3    Hutcheon, D.F.4    Kafonek, D.R.5    Brandenburg, S.6
  • 21
    • 84883154469 scopus 로고    scopus 로고
    • LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer
    • doi: 10.1038/bjc.2013.364
    • Ding, J., Zhang, Z. M., Xia, Y., Liao, G. Q., Pan, Y., Liu, S., et al. (2013). LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer. Br. J. Cancer 109, 994-1003. doi: 10.1038/bjc.2013.364
    • (2013) Br. J. Cancer , vol.109 , pp. 994-1003
    • Ding, J.1    Zhang, Z.M.2    Xia, Y.3    Liao, G.Q.4    Pan, Y.5    Liu, S.6
  • 22
    • 84873564427 scopus 로고    scopus 로고
    • Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns
    • doi: 10.1093/carcin/bgs331
    • Doig, C. L., Singh, P. K., Dhiman, V. K., Thorne, J. L., Battaglia, S., Sobolewski, M., et al. (2013). Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns. Carcinogenesis 34, 248-256. doi: 10.1093/carcin/bgs331
    • (2013) Carcinogenesis , vol.34 , pp. 248-256
    • Doig, C.L.1    Singh, P.K.2    Dhiman, V.K.3    Thorne, J.L.4    Battaglia, S.5    Sobolewski, M.6
  • 23
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • doi: 10.1126/science.1083557
    • Eden, A., Gaudet, F., Waghmare, A., and Jaenisch, R. (2003). Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300, 455. doi: 10.1126/science.1083557
    • (2003) Science , vol.300 , pp. 455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3    Jaenisch, R.4
  • 24
    • 34547792388 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer: the DNA hypermethylome
    • doi: 10.1093/hmg/ddm018
    • Esteller, M. (2007a). Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum. Mol. Genet. 16, Spec No 1, R50-R59. doi: 10.1093/hmg/ddm018
    • (2007) Hum. Mol. Genet. , vol.16 , Issue.SPEC. 1
    • Esteller, M.1
  • 25
    • 31444437920 scopus 로고    scopus 로고
    • Epigenetics provides a new generation of oncogenes and tumour-suppressor genes
    • doi: 10.1038/sj.bjc.6602918
    • Esteller, M. (2007b). Epigenetics provides a new generation of oncogenes and tumour-suppressor genes. Br. J. Cancer 96(Suppl.), R26-R30. doi: 10.1038/sj.bjc.6602918
    • (2007) Br. J. Cancer , vol.96 , Issue.SUPPL.
    • Esteller, M.1
  • 26
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • doi: 10.1056/NEJMra072067
    • Esteller, M. (2008). Epigenetics in cancer. N. Engl. J. Med. 358, 1148-1159. doi: 10.1056/NEJMra072067
    • (2008) N. Engl. J. Med. , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 27
    • 0032706744 scopus 로고    scopus 로고
    • hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis
    • doi: 10.1016/S0002-9440(10)65492-2
    • Esteller, M., Catasus, L., Matias-Guiu, X., Mutter, G. L., Prat, J., Baylin, S. B., et al. (1999). hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis. Am. J. Pathol. 155, 1767-1772. doi: 10.1016/S0002-9440(10)65492-2
    • (1999) Am. J. Pathol. , vol.155 , pp. 1767-1772
    • Esteller, M.1    Catasus, L.2    Matias-Guiu, X.3    Mutter, G.L.4    Prat, J.5    Baylin, S.B.6
  • 28
    • 0036392059 scopus 로고    scopus 로고
    • DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms
    • doi: 10.1016/S1044-579X(02)00059-7
    • Feinberg, A. P., Cui, H., and Ohlsson, R. (2002). DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms. Semin. Cancer Biol. 12, 389-398. doi: 10.1016/S1044-579X(02)00059-7
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 389-398
    • Feinberg, A.P.1    Cui, H.2    Ohlsson, R.3
  • 29
    • 79956323623 scopus 로고    scopus 로고
    • Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
    • doi: 10.1038/nature10008
    • Ficz, G., Branco, M. R., Seisenberger, S., Santos, F., Krueger, F., Hore, T. A., et al. (2011). Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473, 398-402. doi: 10.1038/nature10008
    • (2011) Nature , vol.473 , pp. 398-402
    • Ficz, G.1    Branco, M.R.2    Seisenberger, S.3    Santos, F.4    Krueger, F.5    Hore, T.A.6
  • 31
    • 33745146571 scopus 로고    scopus 로고
    • Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells
    • doi: 10.1101/gad.388206
    • Fodor, B. D., Kubicek, S., Yonezawa, M., O'Sullivan, R. J., Sengupta, R., Perez-Burgos, L., et al. (2006). Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells. Genes Dev. 20, 1557-1562. doi: 10.1101/gad.388206
    • (2006) Genes Dev. , vol.20 , pp. 1557-1562
    • Fodor, B.D.1    Kubicek, S.2    Yonezawa, M.3    O'Sullivan, R.J.4    Sengupta, R.5    Perez-Burgos, L.6
  • 32
    • 36049022778 scopus 로고    scopus 로고
    • JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes
    • doi: 10.1038/nature06255
    • Frescas, D., Guardavaccaro, D., Bassermann, F., Koyama-Nasu, R., and Pagano, M. (2007). JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes. Nature 450, 309-313. doi: 10.1038/nature06255
    • (2007) Nature , vol.450 , pp. 309-313
    • Frescas, D.1    Guardavaccaro, D.2    Bassermann, F.3    Koyama-Nasu, R.4    Pagano, M.5
  • 33
    • 56449126497 scopus 로고    scopus 로고
    • KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state
    • doi: 10.4161/cc.7.22.7062
    • Frescas, D., Guardavaccaro, D., Kuchay, S. M., Kato, H., Poleshko, A., Basrur, V., et al. (2008). KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state. Cell Cycle 7, 3539-3547. doi: 10.4161/cc.7.22.7062
    • (2008) Cell Cycle , vol.7 , pp. 3539-3547
    • Frescas, D.1    Guardavaccaro, D.2    Kuchay, S.M.3    Kato, H.4    Poleshko, A.5    Basrur, V.6
  • 35
    • 33846690407 scopus 로고    scopus 로고
    • Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors
    • doi: 10.1016/j.cell.2006.12.038
    • Garcia-Bassets, I., Kwon, Y. S., Telese, F., Prefontaine, G. G., Hutt, K. R., Cheng, C. S., et al. (2007). Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell 128, 505-518. doi: 10.1016/j.cell.2006.12.038
    • (2007) Cell , vol.128 , pp. 505-518
    • Garcia-Bassets, I.1    Kwon, Y.S.2    Telese, F.3    Prefontaine, G.G.4    Hutt, K.R.5    Cheng, C.S.6
  • 36
    • 0023216891 scopus 로고
    • CpG islands in vertebrate genomes
    • doi: 10.1016/0022-2836(87)90689-9
    • Gardiner-Garden, M., and Frommer, M. (1987). CpG islands in vertebrate genomes. J. Mol. Biol. 196, 261-282. doi: 10.1016/0022-2836(87)90689-9
    • (1987) J. Mol. Biol. , vol.196 , pp. 261-282
    • Gardiner-Garden, M.1    Frommer, M.2
  • 37
    • 0642336647 scopus 로고    scopus 로고
    • Short-chain fatty acids and colon cancer cells: the vitamin D receptor-butyrate connection
    • doi: 10.1007/978-3-642-55580-0_18
    • Gaschott, T., and Stein, J. (2003). Short-chain fatty acids and colon cancer cells: the vitamin D receptor-butyrate connection. Recent Results Cancer Res. 164, 247-257. doi: 10.1007/978-3-642-55580-0_18
    • (2003) Recent Results Cancer Res. , vol.164 , pp. 247-257
    • Gaschott, T.1    Stein, J.2
  • 38
    • 54349093531 scopus 로고    scopus 로고
    • HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling
    • doi: 10.4161/cbt.7.10.6561
    • Godman, C. A., Joshi, R., Tierney, B. R., Greenspan, E., Rasmussen, T. P., Wang, H. W., et al. (2008). HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling. Cancer Biol. Ther. 7, 1570-1580. doi: 10.4161/cbt.7.10.6561
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 1570-1580
    • Godman, C.A.1    Joshi, R.2    Tierney, B.R.3    Greenspan, E.4    Rasmussen, T.P.5    Wang, H.W.6
  • 39
    • 0031042732 scopus 로고    scopus 로고
    • Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism
    • doi: 10.1038/ki.1997.41
    • Gogusev, J., Duchambon, P., Hory, B., Giovannini, M., Goureau, Y., Sarfati, E., et al. (1997). Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism. Kidney Int. 51, 328-336. doi: 10.1038/ki.1997.41
    • (1997) Kidney Int. , vol.51 , pp. 328-336
    • Gogusev, J.1    Duchambon, P.2    Hory, B.3    Giovannini, M.4    Goureau, Y.5    Sarfati, E.6
  • 40
    • 84859893371 scopus 로고    scopus 로고
    • Histone methylation: a dynamic mark in health, disease and inheritance
    • doi: 10.1038/nrg3173
    • Greer, E. L., and Shi, Y. (2012). Histone methylation: a dynamic mark in health, disease and inheritance. Nat. Rev. Genet. 13, 343-357. doi: 10.1038/nrg3173
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 343-357
    • Greer, E.L.1    Shi, Y.2
  • 41
    • 0024365892 scopus 로고
    • Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
    • doi: 10.1007/BF00286709
    • Greger, V., Passarge, E., Höpping, W., Messmer, E., and Horsthemke, B. (1989). Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet. 83, 155-158. doi: 10.1007/BF00286709
    • (1989) Hum. Genet. , vol.83 , pp. 155-158
    • Greger, V.1    Passarge, E.2    Höpping, W.3    Messmer, E.4    Horsthemke, B.5
  • 42
    • 0019875880 scopus 로고
    • Methylation of CpG sequences in eukaryotic DNA
    • doi: 10.1016/0014-5793(81)80055-5
    • Gruenbaum, Y., Stein, R., Cedar, H., and Razin, A. (1981). Methylation of CpG sequences in eukaryotic DNA. FEBS Lett. 124, 67-71. doi: 10.1016/0014-5793(81)80055-5
    • (1981) FEBS Lett. , vol.124 , pp. 67-71
    • Gruenbaum, Y.1    Stein, R.2    Cedar, H.3    Razin, A.4
  • 43
    • 33845868198 scopus 로고    scopus 로고
    • Sirtuins as potential targets for metabolic syndrome
    • doi: 10.1038/nature05486
    • Guarente, L. (2006). Sirtuins as potential targets for metabolic syndrome. Nature 444, 868-874. doi: 10.1038/nature05486
    • (2006) Nature , vol.444 , pp. 868-874
    • Guarente, L.1
  • 44
    • 79951777299 scopus 로고    scopus 로고
    • Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells
    • doi: 10.1186/1471-2407-11-81
    • Habano, W., Gamo, T., Terashima, J., Sugai, T., Otsuka, K., Wakabayashi, G., et al. (2011). Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells. BMC Cancer 11:81. doi: 10.1186/1471-2407-11-81
    • (2011) BMC Cancer , vol.11 , pp. 81
    • Habano, W.1    Gamo, T.2    Terashima, J.3    Sugai, T.4    Otsuka, K.5    Wakabayashi, G.6
  • 45
    • 57749170458 scopus 로고    scopus 로고
    • The many roles of histone deacetylases in development and physiology: implications for disease and therapy
    • doi: 10.1038/nrg2485
    • Haberland, M., Montgomery, R. L., and Olson, E. N. (2009). The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat. Rev. Genet. 10, 32-42. doi: 10.1038/nrg2485
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 32-42
    • Haberland, M.1    Montgomery, R.L.2    Olson, E.N.3
  • 46
    • 84872770694 scopus 로고    scopus 로고
    • Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine
    • doi: 10.1126/science.1229277
    • Hackett, J. A., Sengupta, R., Zylicz, J. J., Murakami, K., Lee, C., Down, T. A., et al. (2013). Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine. Science 339, 448-452. doi: 10.1126/science.1229277
    • (2013) Science , vol.339 , pp. 448-452
    • Hackett, J.A.1    Sengupta, R.2    Zylicz, J.J.3    Murakami, K.4    Lee, C.5    Down, T.A.6
  • 47
    • 1842631408 scopus 로고    scopus 로고
    • Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer
    • doi: 10.1002/pros.20022
    • Halkidou, K., Gaughan, L., Cook, S., Leung, H. Y., Neal, D. E., and Robson, C. N. (2004). Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer. Prostate 59, 177-189. doi: 10.1002/pros.20022
    • (2004) Prostate , vol.59 , pp. 177-189
    • Halkidou, K.1    Gaughan, L.2    Cook, S.3    Leung, H.Y.4    Neal, D.E.5    Robson, C.N.6
  • 48
    • 33947278277 scopus 로고    scopus 로고
    • In silico analysis of the 5' region of the Vitamin D receptor gene: functional implications of evolutionary conservation
    • doi: 10.1016/j.jsbmb.2006.12.046
    • Halsall, J. A., Osborne, J. E., Hutchinson, P. E., and Pringle, J. H. (2007). In silico analysis of the 5' region of the Vitamin D receptor gene: functional implications of evolutionary conservation. J. Steroid. Biochem. Mol. Biol. 103, 352-356. doi: 10.1016/j.jsbmb.2006.12.046
    • (2007) J. Steroid. Biochem. Mol. Biol. , vol.103 , pp. 352-356
    • Halsall, J.A.1    Osborne, J.E.2    Hutchinson, P.E.3    Pringle, J.H.4
  • 50
    • 0024003456 scopus 로고
    • A direct link between core histone acetylation and transcriptionally active chromatin
    • Hebbes, T. R., Thorne, A. W., and Crane-Robinson, C. (1988). A direct link between core histone acetylation and transcriptionally active chromatin. EMBO J. 7, 1395-1402.
    • (1988) EMBO J. , vol.7 , pp. 1395-1402
    • Hebbes, T.R.1    Thorne, A.W.2    Crane-Robinson, C.3
  • 51
    • 84886808679 scopus 로고    scopus 로고
    • Chromatin proteins and modifications as drug targets
    • doi: 10.1038/nature12751
    • Helin, K., and Dhanak, D. (2013). Chromatin proteins and modifications as drug targets. Nature 502, 480-488. doi: 10.1038/nature12751
    • (2013) Nature , vol.502 , pp. 480-488
    • Helin, K.1    Dhanak, D.2
  • 52
    • 3042687453 scopus 로고    scopus 로고
    • Regulation of gene expression by the CYP27B1 promoter-study of a transgenic mouse model
    • doi: 10.1016/j.jsbmb.2004.03.093.
    • Hendrix, I., Anderson, P., May, B., and Morris, H. (2004). Regulation of gene expression by the CYP27B1 promoter-study of a transgenic mouse model. J. Steroid Biochem. Mol. Biol. 89-90, 139-142. doi: 10.1016/j.jsbmb.2004.03.093
    • (2004) J. Steroid Biochem. Mol. Biol. , vol.89-90 , pp. 139-142
    • Hendrix, I.1    Anderson, P.2    May, B.3    Morris, H.4
  • 53
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • doi: 10.1056/NEJMra023075
    • Herman, J. G., and Baylin, S. B. (2003). Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 349, 2042-2054. doi: 10.1056/NEJMra023075
    • (2003) N. Engl. J. Med. , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 55
    • 84879954055 scopus 로고    scopus 로고
    • Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer
    • doi: 10.1002/ijc.28143
    • Höbaus, J., Hummel, D. M., Thiem, U., Fetahu, I. S., Aggarwal, A., Müllauer, L., et al. (2013b). Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer. Int. J. Cancer 133, 1380-1388. doi: 10.1002/ijc.28143
    • (2013) Int. J. Cancer , vol.133 , pp. 1380-1388
    • Höbaus, J.1    Hummel, D.M.2    Thiem, U.3    Fetahu, I.S.4    Aggarwal, A.5    Müllauer, L.6
  • 56
    • 84878247928 scopus 로고    scopus 로고
    • Role of calcium, vitamin d, and the extrarenal vitamin d hydroxylases in carcinogenesis
    • doi: 10.2174/187152013804487434
    • Hobaus, J., Thiem, U., Hummel, D. M., and Kallay, E. (2013). Role of calcium, vitamin d, and the extrarenal vitamin d hydroxylases in carcinogenesis. Anticancer Agents Med. Chem. 13, 20-35. doi: 10.2174/187152013804487434
    • (2013) Anticancer Agents Med. Chem. , vol.13 , pp. 20-35
    • Hobaus, J.1    Thiem, U.2    Hummel, D.M.3    Kallay, E.4
  • 57
    • 84869044855 scopus 로고    scopus 로고
    • Epigenetic methylation of parathyroid CaR and VDR promoters in experimental secondary hyperparathyroidism
    • doi: 10.1155/2012/123576
    • Hofman-Bang, J., Gravesen, E., Olgaard, K., and Lewin, E. (2012). Epigenetic methylation of parathyroid CaR and VDR promoters in experimental secondary hyperparathyroidism. Int. J. Nephrol. 2012:123576. doi: 10.1155/2012/123576
    • (2012) Int. J. Nephrol. , vol.2012 , pp. 123576
    • Hofman-Bang, J.1    Gravesen, E.2    Olgaard, K.3    Lewin, E.4
  • 58
    • 33947302685 scopus 로고    scopus 로고
    • The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases
    • doi: 10.1016/j.cell.2007.02.017
    • Iwase, S., Lan, F., Bayliss, P., De La Torre-Ubieta, L., Huarte, M., Qi, H. H., et al. (2007). The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell 128, 1077-1088. doi: 10.1016/j.cell.2007.02.017
    • (2007) Cell , vol.128 , pp. 1077-1088
    • Iwase, S.1    Lan, F.2    Bayliss, P.3    De La Torre-Ubieta, L.4    Huarte, M.5    Qi, H.H.6
  • 59
    • 0346220267 scopus 로고    scopus 로고
    • 3 in ovarian cancer cells mediated through the induction of GADD45 via an exonic enhancer
    • doi: 10.1074/jbc.M308430200
    • 3 in ovarian cancer cells mediated through the induction of GADD45 via an exonic enhancer. J. Biol. Chem. 278, 48030-48040. doi: 10.1074/jbc.M308430200
    • (2003) J. Biol. Chem. , vol.278 , pp. 48030-48040
    • Jiang, F.1    Li, P.2    Fornace, A.J.3    Nicosia, S.V.4    Bai, W.5
  • 60
    • 84869046975 scopus 로고    scopus 로고
    • DNA methyltransferases, DNA damage repair, and cancer
    • doi: 10.1007/978-1-4419-9967-2_1
    • Jin, B., and Robertson, K. D. (2013). DNA methyltransferases, DNA damage repair, and cancer. Adv. Exp. Med. Biol. 754, 3-29. doi: 10.1007/978-1-4419-9967-2_1
    • (2013) Adv. Exp. Med. Biol. , vol.754 , pp. 3-29
    • Jin, B.1    Robertson, K.D.2
  • 61
    • 77954761786 scopus 로고    scopus 로고
    • Epigenetic silencing of CYP24 in the tumor microenvironment
    • doi: 10.1016/j.jsbmb.2010.03.046
    • Johnson, C. S., Chung, I., and Trump, D. L. (2010). Epigenetic silencing of CYP24 in the tumor microenvironment. J. Steroid Biochem. Mol. Biol. 121, 338-342. doi: 10.1016/j.jsbmb.2010.03.046
    • (2010) J. Steroid Biochem. Mol. Biol. , vol.121 , pp. 338-342
    • Johnson, C.S.1    Chung, I.2    Trump, D.L.3
  • 62
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • doi: 10.1016/j.cell.2007.01.029
    • Jones, P. A., and Baylin, S. B. (2007). The epigenomics of cancer. Cell 128, 683-692. doi: 10.1016/j.cell.2007.01.029
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 63
    • 0031837109 scopus 로고    scopus 로고
    • Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
    • doi: 10.1038/561
    • Jones, P. L., Veenstra, G. J., Wade, P. A., Vermaak, D., Kass, S. U., Landsberger, N., et al. (1998). Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat. Genet. 19, 187-191. doi: 10.1038/561
    • (1998) Nat. Genet. , vol.19 , pp. 187-191
    • Jones, P.L.1    Veenstra, G.J.2    Wade, P.A.3    Vermaak, D.4    Kass, S.U.5    Landsberger, N.6
  • 64
    • 71549154751 scopus 로고    scopus 로고
    • Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer
    • doi: 10.1111/j.1600-079X.2009.00729.x
    • Jung-Hynes, B., Reiter, R. J., and Ahmad, N. (2010). Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer. J. Pineal Res. 48, 9-19. doi: 10.1111/j.1600-079X.2009.00729.x
    • (2010) J. Pineal Res. , vol.48 , pp. 9-19
    • Jung-Hynes, B.1    Reiter, R.J.2    Ahmad, N.3
  • 65
    • 33845762289 scopus 로고    scopus 로고
    • Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence
    • doi: 10.1158/0008-5472.CAN-06-1570
    • Kahl, P., Gullotti, L., Heukamp, L. C., Wolf, S., Friedrichs, N., Vorreuther, R., et al. (2006). Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence. Cancer Res. 66, 11341-11347. doi: 10.1158/0008-5472.CAN-06-1570
    • (2006) Cancer Res. , vol.66 , pp. 11341-11347
    • Kahl, P.1    Gullotti, L.2    Heukamp, L.C.3    Wolf, S.4    Friedrichs, N.5    Vorreuther, R.6
  • 66
    • 80051622767 scopus 로고    scopus 로고
    • Impact of vitamin D metabolism on clinical epigenetics
    • doi: 10.1007/s13148-011-0021-y
    • Karlic, H., and Varga, F. (2011). Impact of vitamin D metabolism on clinical epigenetics. Clin. Epigenetics 2, 55-61. doi: 10.1007/s13148-011-0021-y
    • (2011) Clin. Epigenetics , vol.2 , pp. 55-61
    • Karlic, H.1    Varga, F.2
  • 68
    • 0019485450 scopus 로고
    • 3 1 alpha-hydroxylase and 24-hydroxylase along the rat nephron
    • doi: 10.1073/pnas.78.2.1199
    • 3 1 alpha-hydroxylase and 24-hydroxylase along the rat nephron. Proc. Natl. Acad. Sci. U.S.A. 78, 1199-1203. doi: 10.1073/pnas.78.2.1199
    • (1981) Proc. Natl. Acad. Sci. U.S.A. , vol.78 , pp. 1199-1203
    • Kawashima, H.1    Torikai, S.2    Kurokawa, K.3
  • 69
    • 18044385966 scopus 로고    scopus 로고
    • Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells
    • doi: 10.1016/j.jsbmb.2004.12.022
    • Khorchide, M., Lechner, D., and Cross, H. S. (2005). Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells. J. Steroid Biochem. Mol. Biol. 93, 167-172. doi: 10.1016/j.jsbmb.2004.12.022
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.93 , pp. 167-172
    • Khorchide, M.1    Lechner, D.2    Cross, H.S.3
  • 70
    • 0036683055 scopus 로고    scopus 로고
    • Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases
    • doi: 10.1093/emboj/cdf401
    • Kim, G. D., Ni, J., Kelesoglu, N., Roberts, R. J., and Pradhan, S. (2002). Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases. EMBO J. 21, 4183-4195. doi: 10.1093/emboj/cdf401
    • (2002) EMBO J. , vol.21 , pp. 4183-4195
    • Kim, G.D.1    Ni, J.2    Kelesoglu, N.3    Roberts, R.J.4    Pradhan, S.5
  • 71
    • 33847043095 scopus 로고    scopus 로고
    • 1alpha,25(OH)2D3-induced DNA methylation suppresses the human CYP27B1 gene
    • doi: 10.1016/j.mce.2006.12.014.
    • Kim, M. S., Fujiki, R., Kitagawa, H., and Kato, S. (2007a). 1alpha,25(OH)2D3-induced DNA methylation suppresses the human CYP27B1 gene. Mol. Cell Endocrinol. 265-266, 168-173. doi: 10.1016/j.mce.2006.12.014
    • (2007) Mol. Cell Endocrinol , vol.265-266 , pp. 168-173
    • Kim, M.S.1    Fujiki, R.2    Kitagawa, H.3    Kato, S.4
  • 72
    • 33846658748 scopus 로고    scopus 로고
    • 1Alpha,25(OH)2D3-induced transrepression by vitamin D receptor through E-box-type elements in the human parathyroid hormone gene promoter
    • doi: 10.1210/me.2006-0231
    • Kim, M. S., Fujiki, R., Murayama, A., Kitagawa, H., Yamaoka, K., Yamamoto, Y., et al. (2007b). 1Alpha,25(OH)2D3-induced transrepression by vitamin D receptor through E-box-type elements in the human parathyroid hormone gene promoter. Mol. Endocrinol. 21, 334-342. doi: 10.1210/me.2006-0231
    • (2007) Mol. Endocrinol. , vol.21 , pp. 334-342
    • Kim, M.S.1    Fujiki, R.2    Murayama, A.3    Kitagawa, H.4    Yamaoka, K.5    Yamamoto, Y.6
  • 73
    • 40549094047 scopus 로고    scopus 로고
    • Predicting DNA methylation susceptibility using CpG flanking sequences
    • Kim, S., Li, M., Paik, H., Nephew, K., Shi, H., Kramer, R., et al. (2008). Predicting DNA methylation susceptibility using CpG flanking sequences. Pac. Symp. Biocomput. 13, 315-326.
    • (2008) Pac. Symp. Biocomput. , vol.13 , pp. 315-326
    • Kim, S.1    Li, M.2    Paik, H.3    Nephew, K.4    Shi, H.5    Kramer, R.6
  • 74
    • 33745847680 scopus 로고    scopus 로고
    • The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36
    • doi: 10.1038/nature04853
    • Klose, R. J., Yamane, K., Bae, Y., Zhang, D., Erdjument-Bromage, H., Tempst, P., et al. (2006). The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature 442, 312-316. doi: 10.1038/nature04853
    • (2006) Nature , vol.442 , pp. 312-316
    • Klose, R.J.1    Yamane, K.2    Bae, Y.3    Zhang, D.4    Erdjument-Bromage, H.5    Tempst, P.6
  • 75
    • 33847401344 scopus 로고    scopus 로고
    • The retinoblastoma binding protein RBP2 is an H3K4 demethylase
    • doi: 10.1016/j.cell.2007.02.013
    • Klose, R. J., Yan, Q., Tothova, Z., Yamane, K., Erdjument-Bromage, H., Tempst, P., et al. (2007). The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell 128, 889-900. doi: 10.1016/j.cell.2007.02.013
    • (2007) Cell , vol.128 , pp. 889-900
    • Klose, R.J.1    Yan, Q.2    Tothova, Z.3    Yamane, K.4    Erdjument-Bromage, H.5    Tempst, P.6
  • 76
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • doi: 10.1016/j.cell.2007.02.005
    • Kouzarides, T. (2007). Chromatin modifications and their function. Cell 128, 693-705. doi: 10.1016/j.cell.2007.02.005
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 77
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • doi: 10.1126/science.1169786
    • Kriaucionis, S., and Heintz, N. (2009). The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324, 929-930. doi: 10.1126/science.1169786
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 78
    • 0037383786 scopus 로고    scopus 로고
    • The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene
    • doi: 10.1128/MCB.23.8.2669-2679.2003
    • Lagger, G., Doetzlhofer, A., Schuettengruber, B., Haidweger, E., Simboeck, E., Tischler, J., et al. (2003). The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene. Mol. Cell Biol. 23, 2669-2679. doi: 10.1128/MCB.23.8.2669-2679.2003
    • (2003) Mol. Cell Biol. , vol.23 , pp. 2669-2679
    • Lagger, G.1    Doetzlhofer, A.2    Schuettengruber, B.3    Haidweger, E.4    Simboeck, E.5    Tischler, J.6
  • 79
    • 0035099604 scopus 로고    scopus 로고
    • Transcriptional coregulators of the nuclear receptor superfamily: coactivators and corepressors
    • doi: 10.1007/PL00000856
    • Lee, J. W., Lee, Y. C., Na, S. Y., Jung, D. J., and Lee, S. K. (2001). Transcriptional coregulators of the nuclear receptor superfamily: coactivators and corepressors. Cell Mol. Life Sci. 58, 289-297. doi: 10.1007/PL00000856
    • (2001) Cell Mol. Life Sci. , vol.58 , pp. 289-297
    • Lee, J.W.1    Lee, Y.C.2    Na, S.Y.3    Jung, D.J.4    Lee, S.K.5
  • 80
    • 0036066178 scopus 로고    scopus 로고
    • Persistent downregulation of calcium-sensing receptor mRNA in rat parathyroids when severe secondary hyperparathyroidism is reversed by an isogenic kidney transplantation
    • doi: 10.1097/01.ASN.0000024439.38838.03
    • Lewin, E., Garfia, B., Recio, F. L., Rodriguez, M., and Olgaard, K. (2002). Persistent downregulation of calcium-sensing receptor mRNA in rat parathyroids when severe secondary hyperparathyroidism is reversed by an isogenic kidney transplantation. J. Am. Soc. Nephrol. 13, 2110-2116. doi: 10.1097/01.ASN.0000024439.38838.03
    • (2002) J. Am. Soc. Nephrol. , vol.13 , pp. 2110-2116
    • Lewin, E.1    Garfia, B.2    Recio, F.L.3    Rodriguez, M.4    Olgaard, K.5
  • 81
    • 84894088172 scopus 로고    scopus 로고
    • Hypermethylation of the CDKN2A gene promoter is a frequent epigenetic change in periocular sebaceous carcinoma and is associated with younger patient age
    • doi: 10.1016/j.humpath.2013.10.019
    • Liau, J. Y., Liao, S. L., Hsiao, C. H., Lin, M. C., Chang, H. C., and Kuo, K. T. (2014). Hypermethylation of the CDKN2A gene promoter is a frequent epigenetic change in periocular sebaceous carcinoma and is associated with younger patient age. Hum Pathol. 45, 533-539. doi: 10.1016/j.humpath.2013.10.019
    • (2014) Hum Pathol. , vol.45 , pp. 533-539
    • Liau, J.Y.1    Liao, S.L.2    Hsiao, C.H.3    Lin, M.C.4    Chang, H.C.5    Kuo, K.T.6
  • 82
    • 56849114113 scopus 로고    scopus 로고
    • Heterochromatin protein 1a stimulates histone H3 lysine 36 demethylation by the Drosophila KDM4A demethylase
    • doi: 10.1016/j.molcel.2008.11.008
    • Lin, C. H., Li, B., Swanson, S., Zhang, Y., Florens, L., Washburn, M. P., et al. (2008). Heterochromatin protein 1a stimulates histone H3 lysine 36 demethylation by the Drosophila KDM4A demethylase. Mol. Cell 32, 696-706. doi: 10.1016/j.molcel.2008.11.008
    • (2008) Mol. Cell , vol.32 , pp. 696-706
    • Lin, C.H.1    Li, B.2    Swanson, S.3    Zhang, Y.4    Florens, L.5    Washburn, M.P.6
  • 83
    • 84878791222 scopus 로고    scopus 로고
    • Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer
    • doi: 10.1002/path.4179
    • Lin, Y. W., Ren, L. L., Xiong, H., Du, W., Yu, Y. N., Sun, T. T., et al. (2013). Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer. J. Pathol. 230, 277-290. doi: 10.1002/path.4179
    • (2013) J. Pathol. , vol.230 , pp. 277-290
    • Lin, Y.W.1    Ren, L.L.2    Xiong, H.3    Du, W.4    Yu, Y.N.5    Sun, T.T.6
  • 84
    • 33746228121 scopus 로고    scopus 로고
    • Sirtuins in aging and age-related disease
    • doi: 10.1016/j.cell.2006.07.002
    • Longo, V. D., and Kennedy, B. K. (2006). Sirtuins in aging and age-related disease. Cell 126, 257-268. doi: 10.1016/j.cell.2006.07.002
    • (2006) Cell , vol.126 , pp. 257-268
    • Longo, V.D.1    Kennedy, B.K.2
  • 85
  • 86
    • 0038748632 scopus 로고    scopus 로고
    • A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer
    • doi: 10.1074/jbc.274.22.15633
    • Lu, P. J., Sundquist, K., Baeckstrom, D., Poulsom, R., Hanby, A., Meier-Ewert, S., et al. (1999). A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer. J. Biol. Chem. 274, 15633-15645. doi: 10.1074/jbc.274.22.15633
    • (1999) J. Biol. Chem. , vol.274 , pp. 15633-15645
    • Lu, P.J.1    Sundquist, K.2    Baeckstrom, D.3    Poulsom, R.4    Hanby, A.5    Meier-Ewert, S.6
  • 87
    • 77955037065 scopus 로고    scopus 로고
    • Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer
    • doi: 10.1158/0008-5472.CAN-10-0617
    • Luo, W., Karpf, A. R., Deeb, K. K., Muindi, J. R., Morrison, C. D., Johnson, C. S., et al. (2010). Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer. Cancer Res. 70, 5953-5962. doi: 10.1158/0008-5472.CAN-10-0617
    • (2010) Cancer Res. , vol.70 , pp. 5953-5962
    • Luo, W.1    Karpf, A.R.2    Deeb, K.K.3    Muindi, J.R.4    Morrison, C.D.5    Johnson, C.S.6
  • 88
    • 77954388100 scopus 로고    scopus 로고
    • DNA methylation-related vitamin D receptor insensitivity in breast cancer
    • doi: 10.4161/cbt.10.1.11994
    • Marik, R., Fackler, M., Gabrielson, E., Zeiger, M. A., Sukumar, S., Stearns, V., et al. (2010). DNA methylation-related vitamin D receptor insensitivity in breast cancer. Cancer Biol. Ther. 10, 44-53. doi: 10.4161/cbt.10.1.11994
    • (2010) Cancer Biol. Ther. , vol.10 , pp. 44-53
    • Marik, R.1    Fackler, M.2    Gabrielson, E.3    Zeiger, M.A.4    Sukumar, S.5    Stearns, V.6
  • 90
    • 49649125042 scopus 로고    scopus 로고
    • Genome-scale DNA methylation maps of pluripotent and differentiated cells
    • doi: 10.1038/nature07107
    • Meissner, A., Mikkelsen, T. S., Gu, H., Wernig, M., Hanna, J., Sivachenko, A., et al. (2008). Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454, 766-770. doi: 10.1038/nature07107
    • (2008) Nature , vol.454 , pp. 766-770
    • Meissner, A.1    Mikkelsen, T.S.2    Gu, H.3    Wernig, M.4    Hanna, J.5    Sivachenko, A.6
  • 91
    • 24144462170 scopus 로고    scopus 로고
    • LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription
    • doi: 10.1038/nature04020
    • Metzger, E., Wissmann, M., Yin, N., Müller, J. M., Schneider, R., Peters, A. H., et al. (2005). LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature 437, 436-439. doi: 10.1038/nature04020
    • (2005) Nature , vol.437 , pp. 436-439
    • Metzger, E.1    Wissmann, M.2    Yin, N.3    Müller, J.M.4    Schneider, R.5    Peters, A.H.6
  • 92
    • 84906791289 scopus 로고    scopus 로고
    • 3 induced histone profiles guide discovery of VDR action sites
    • doi: 10.1016/j.jsbmb.2013.09.005. [Epub ahead of print].
    • 3 induced histone profiles guide discovery of VDR action sites. J. Steroid Biochem. Mol. Biol. doi: 10.1016/j.jsbmb.2013.09.005. [Epub ahead of print].
    • (2013) J. Steroid Biochem. Mol. Biol.
    • Meyer, M.B.1    Benkusky, N.A.2    Pike, J.W.3
  • 94
    • 77953644347 scopus 로고    scopus 로고
    • Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases
    • doi: 10.1146/annurev.biochem.78.070907.103946
    • Mosammaparast, N., and Shi, Y. (2010). Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases. Annu. Rev. Biochem. 79, 155-179. doi: 10.1146/annurev.biochem.78.070907.103946
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 155-179
    • Mosammaparast, N.1    Shi, Y.2
  • 95
    • 58249096131 scopus 로고    scopus 로고
    • HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism
    • doi: 10.1038/onc.2008.371
    • Mottet, D., Pirotte, S., Lamour, V., Hagedorn, M., Javerzat, S., Bikfalvi, A., et al. (2009). HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism. Oncogene 28, 243-256. doi: 10.1038/onc.2008.371
    • (2009) Oncogene , vol.28 , pp. 243-256
    • Mottet, D.1    Pirotte, S.2    Lamour, V.3    Hagedorn, M.4    Javerzat, S.5    Bikfalvi, A.6
  • 96
    • 2342623470 scopus 로고    scopus 로고
    • Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching
    • doi: 10.1038/sj.emboj.7600157
    • Murayama, A., Kim, M. S., Yanagisawa, J., Takeyama, K., and Kato, S. (2004). Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching. EMBO J. 23, 1598-1608. doi: 10.1038/sj.emboj.7600157
    • (2004) EMBO J. , vol.23 , pp. 1598-1608
    • Murayama, A.1    Kim, M.S.2    Yanagisawa, J.3    Takeyama, K.4    Kato, S.5
  • 97
    • 23744437421 scopus 로고    scopus 로고
    • Noncalcemic actions of vitamin D receptor ligands
    • doi: 10.1210/er.2004-0002
    • Nagpal, S., Na, S., and Rathnachalam, R. (2005). Noncalcemic actions of vitamin D receptor ligands. Endocr. Rev. 26, 662-687. doi: 10.1210/er.2004-0002
    • (2005) Endocr. Rev. , vol.26 , pp. 662-687
    • Nagpal, S.1    Na, S.2    Rathnachalam, R.3
  • 98
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • doi: 10.1038/30764
    • Nan, X., Ng, H. H., Johnson, C. A., Laherty, C. D., Turner, B. M., Eisenman, R. N., et al. (1998). Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393, 386-389. doi: 10.1038/30764
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6
  • 99
    • 77957110074 scopus 로고    scopus 로고
    • Vitamin D nutritional policy needs a vision for the future
    • doi: 10.1258/ebm.2010.010014
    • Norman, A. W., and Bouillon, R. (2010). Vitamin D nutritional policy needs a vision for the future. Exp. Biol. Med. (Maywood) 235, 1034-1045. doi: 10.1258/ebm.2010.010014
    • (2010) Exp. Biol. Med. (Maywood) , vol.235 , pp. 1034-1045
    • Norman, A.W.1    Bouillon, R.2
  • 100
    • 67649344487 scopus 로고    scopus 로고
    • Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface
    • doi: 10.1074/jbc.M809542200
    • Novakovic, B., Sibson, M., Ng, H. K., Manuelpillai, U., Rakyan, V., Down, T., et al. (2009). Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface. J. Biol. Chem. 284, 14838-14848. doi: 10.1074/jbc.M809542200
    • (2009) J. Biol. Chem. , vol.284 , pp. 14838-14848
    • Novakovic, B.1    Sibson, M.2    Ng, H.K.3    Manuelpillai, U.4    Rakyan, V.5    Down, T.6
  • 101
    • 0041317202 scopus 로고    scopus 로고
    • Extensive methylation of CpG island of CYP24 gene in osteoblastic ROS17/2.8 cells
    • doi: 10.1093/nass/2.1.249.
    • Ohyama, Y., Kusada, T., Yamasaki, T., and Ide, H. (2002). Extensive methylation of CpG island of CYP24 gene in osteoblastic ROS17/2.8 cells. Nucleic Acids Res. Suppl. 249-250. doi: 10.1093/nass/2.1.249
    • (2002) Nucleic Acids Res. Suppl. , pp. 249-250
    • Ohyama, Y.1    Kusada, T.2    Yamasaki, T.3    Ide, H.4
  • 102
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • doi: 10.1016/S0092-8674(00)81656-6
    • Okano, M., Bell, D. W., Haber, D. A., and Li, E. (1999). DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257. doi: 10.1016/S0092-8674(00)81656-6
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 103
    • 0031860739 scopus 로고    scopus 로고
    • Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • doi: 10.1038/890
    • Okano, M., Xie, S., and Li, E. (1998). Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet. 19, 219-220. doi: 10.1038/890
    • (1998) Nat. Genet. , vol.19 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 104
    • 84880600170 scopus 로고    scopus 로고
    • MicroRNA-627 mediates the epigenetic mechanisms of vitamin D to suppress proliferation of human colorectal cancer cells and growth of xenograft tumors in mice
    • doi: 10.1053/j.gastro.2013.04.012
    • Padi, S. K., Zhang, Q., Rustum, Y. M., Morrison, C., and Guo, B. (2013). MicroRNA-627 mediates the epigenetic mechanisms of vitamin D to suppress proliferation of human colorectal cancer cells and growth of xenograft tumors in mice. Gastroenterology 145, 437-446. doi: 10.1053/j.gastro.2013.04.012
    • (2013) Gastroenterology , vol.145 , pp. 437-446
    • Padi, S.K.1    Zhang, Q.2    Rustum, Y.M.3    Morrison, C.4    Guo, B.5
  • 105
    • 76149135992 scopus 로고    scopus 로고
    • Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation
    • doi: 10.1111/j.1742-4658.2009.07542.x
    • Pan, L., Matloob, A. F., Du, J., Pan, H., Dong, Z., Zhao, J., et al. (2010). Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation. FEBS J. 277, 989-999. doi: 10.1111/j.1742-4658.2009.07542.x
    • (2010) FEBS J. , vol.277 , pp. 989-999
    • Pan, L.1    Matloob, A.F.2    Du, J.3    Pan, H.4    Dong, Z.5    Zhao, J.6
  • 106
    • 84891071460 scopus 로고    scopus 로고
    • Histone deacetylases: a saga of perturbed acetylation homeostasis in cancer
    • doi: 10.1369/0022155413506582
    • Parbin, S., Kar, S., Shilpi, A., Sengupta, D., Deb, M., Rath, S. K., et al. (2014). Histone deacetylases: a saga of perturbed acetylation homeostasis in cancer. J. Histochem. Cytochem. 62, 11-33. doi: 10.1369/0022155413506582
    • (2014) J. Histochem. Cytochem. , vol.62 , pp. 11-33
    • Parbin, S.1    Kar, S.2    Shilpi, A.3    Sengupta, D.4    Deb, M.5    Rath, S.K.6
  • 108
    • 78049286684 scopus 로고    scopus 로고
    • Histone demethylases in development and disease
    • doi: 10.1016/j.tcb.2010.08.011
    • Pedersen, M. T., and Helin, K. (2010). Histone demethylases in development and disease. Trends Cell Biol. 20, 662-671. doi: 10.1016/j.tcb.2010.08.011
    • (2010) Trends Cell Biol. , vol.20 , pp. 662-671
    • Pedersen, M.T.1    Helin, K.2
  • 109
    • 55749104413 scopus 로고    scopus 로고
    • Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes
    • Pendas-Franco, N., Aguilera, O., Pereira, F., Gonzalez-Sancho, J. M., and Munoz, A. (2008). Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes. Anticancer Res. 28, 2613-2623.
    • (2008) Anticancer Res. , vol.28 , pp. 2613-2623
    • Pendas-Franco, N.1    Aguilera, O.2    Pereira, F.3    Gonzalez-Sancho, J.M.4    Munoz, A.5
  • 110
    • 81255147963 scopus 로고    scopus 로고
    • KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells
    • doi: 10.1093/hmg/ddr399
    • Pereira, F., Barbachano, A., Silva, J., Bonilla, F., Campbell, M. J., Munoz, A., et al. (2011). KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells. Hum. Mol. Genet. 20, 4655-4665. doi: 10.1093/hmg/ddr399
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 4655-4665
    • Pereira, F.1    Barbachano, A.2    Silva, J.3    Bonilla, F.4    Campbell, M.J.5    Munoz, A.6
  • 111
    • 84858734484 scopus 로고    scopus 로고
    • Vitamin D has wide regulatory effects on histone demethylase genes
    • doi: 10.4161/cc.11.6.19508
    • Pereira, F., Barbachano, A., Singh, P. K., Campbell, M. J., Munoz, A., and Larriba, M. J. (2012). Vitamin D has wide regulatory effects on histone demethylase genes. Cell Cycle 11, 1081-1089. doi: 10.4161/cc.11.6.19508
    • (2012) Cell Cycle , vol.11 , pp. 1081-1089
    • Pereira, F.1    Barbachano, A.2    Singh, P.K.3    Campbell, M.J.4    Munoz, A.5    Larriba, M.J.6
  • 112
    • 38149045693 scopus 로고    scopus 로고
    • DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression
    • doi: 10.1126/science.1147674
    • Perillo, B., Ombra, M. N., Bertoni, A., Cuozzo, C., Sacchetti, S., Sasso, A., et al. (2008). DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression. Science 319, 202-206. doi: 10.1126/science.1147674
    • (2008) Science , vol.319 , pp. 202-206
    • Perillo, B.1    Ombra, M.N.2    Bertoni, A.3    Cuozzo, C.4    Sacchetti, S.5    Sasso, A.6
  • 113
    • 41149116609 scopus 로고    scopus 로고
    • Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process
    • doi: 10.1073/pnas.0711865105
    • Pfau, R., Tzatsos, A., Kampranis, S. C., Serebrennikova, O. B., Bear, S. E., and Tsichlis, P. N. (2008). Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process. Proc. Natl. Acad. Sci. U.SA. 105, 1907-1912. doi: 10.1073/pnas.0711865105
    • (2008) Proc. Natl. Acad. Sci. U.SA. , vol.105 , pp. 1907-1912
    • Pfau, R.1    Tzatsos, A.2    Kampranis, S.C.3    Serebrennikova, O.B.4    Bear, S.E.5    Tsichlis, P.N.6
  • 114
    • 84906790954 scopus 로고    scopus 로고
    • Fundamentals of vitamin D hormone-regulated gene expression
    • doi: 10.1016/j.jsbmb.2013.11.004. [Epub ahead of print].
    • Pike, J. W., and Meyer, M. B. (2013). Fundamentals of vitamin D hormone-regulated gene expression. J. Steroid Biochem. Mol. Biol. doi: 10.1016/j.jsbmb.2013.11.004. [Epub ahead of print].
    • (2013) J. Steroid Biochem. Mol. Biol
    • Pike, J.W.1    Meyer, M.B.2
  • 115
    • 84858154398 scopus 로고    scopus 로고
    • Regulation of target gene expression by the vitamin D receptor - an update on mechanisms
    • doi: 10.1007/s11154-011-9198-9
    • Pike, J. W., Meyer, M. B., and Bishop, K. A. (2012). Regulation of target gene expression by the vitamin D receptor - an update on mechanisms. Rev. Endocr. Metab. Disord. 13, 45-55. doi: 10.1007/s11154-011-9198-9
    • (2012) Rev. Endocr. Metab. Disord. , vol.13 , pp. 45-55
    • Pike, J.W.1    Meyer, M.B.2    Bishop, K.A.3
  • 116
    • 0033918407 scopus 로고    scopus 로고
    • VDR-Alien: a novel, DNA-selective vitamin D(3) receptor-corepressor partnership
    • doi: 10.1096/fj.14.10.1455
    • Polly, P., Herdick, M., Moehren, U., Baniahmad, A., Heinzel, T., and Carlberg, C. (2000). VDR-Alien: a novel, DNA-selective vitamin D(3) receptor-corepressor partnership. FASEB J. 14, 1455-1463. doi: 10.1096/fj.14.10.1455
    • (2000) FASEB J. , vol.14 , pp. 1455-1463
    • Polly, P.1    Herdick, M.2    Moehren, U.3    Baniahmad, A.4    Heinzel, T.5    Carlberg, C.6
  • 117
    • 0035810045 scopus 로고    scopus 로고
    • Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A
    • doi: 10.1038/sj.onc.1204269
    • Rashid, S. F., Moore, J. S., Walker, E., Driver, P. M., Engel, J., Edwards, C. E., et al. (2001). Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. Oncogene 20, 1860-1872. doi: 10.1038/sj.onc.1204269
    • (2001) Oncogene , vol.20 , pp. 1860-1872
    • Rashid, S.F.1    Moore, J.S.2    Walker, E.3    Driver, P.M.4    Engel, J.5    Edwards, C.E.6
  • 118
    • 84867785696 scopus 로고    scopus 로고
    • Vitamin D intake is negatively associated with promoter methylation of the Wnt antagonist gene DKK1 in a large group of colorectal cancer patients
    • doi: 10.1080/01635581.2012.711418
    • Rawson, J. B., Sun, Z., Dicks, E., Daftary, D., Parfrey, P. S., Green, R. C., et al. (2012). Vitamin D intake is negatively associated with promoter methylation of the Wnt antagonist gene DKK1 in a large group of colorectal cancer patients. Nutr. Cancer 64, 919-928. doi: 10.1080/01635581.2012.711418
    • (2012) Nutr. Cancer , vol.64 , pp. 919-928
    • Rawson, J.B.1    Sun, Z.2    Dicks, E.3    Daftary, D.4    Parfrey, P.S.5    Green, R.C.6
  • 119
    • 17744391429 scopus 로고    scopus 로고
    • Co-evolution of X-chromosome inactivation and imprinting in mammals
    • doi: 10.1038/nrg1602
    • Reik, W., and Lewis, A. (2005). Co-evolution of X-chromosome inactivation and imprinting in mammals. Nat. Rev. Genet. 6, 403-410. doi: 10.1038/nrg1602
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 403-410
    • Reik, W.1    Lewis, A.2
  • 120
    • 18344390653 scopus 로고    scopus 로고
    • DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
    • doi: 10.1038/416552a
    • Rhee, I., Bachman, K. E., Park, B. H., Jair, K. W., Yen, R. W., Schuebel, K. E., et al. (2002). DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 416, 552-556. doi: 10.1038/416552a
    • (2002) Nature , vol.416 , pp. 552-556
    • Rhee, I.1    Bachman, K.E.2    Park, B.H.3    Jair, K.W.4    Yen, R.W.5    Schuebel, K.E.6
  • 121
    • 0034720284 scopus 로고    scopus 로고
    • CpG methylation is maintained in human cancer cells lacking DNMT1
    • doi: 10.1038/35010000
    • Rhee, I., Jair, K. W., Yen, R. W., Lengauer, C., Herman, J. G., Kinzler, K. W., et al. (2000). CpG methylation is maintained in human cancer cells lacking DNMT1. Nature 404, 1003-1007. doi: 10.1038/35010000
    • (2000) Nature , vol.404 , pp. 1003-1007
    • Rhee, I.1    Jair, K.W.2    Yen, R.W.3    Lengauer, C.4    Herman, J.G.5    Kinzler, K.W.6
  • 122
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • doi: 10.1038/nrg1655
    • Robertson, K. D. (2005). DNA methylation and human disease. Nat. Rev. Genet. 6, 597-610. doi: 10.1038/nrg1655
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 123
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • doi: 10.1016/j.ccr.2006.04.020
    • Saito, Y., Liang, G., Egger, G., Friedman, J. M., Chuang, J. C., Coetzee, G. A., et al. (2006). Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9, 435-443. doi: 10.1016/j.ccr.2006.04.020
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3    Friedman, J.M.4    Chuang, J.C.5    Coetzee, G.A.6
  • 127
    • 62449197931 scopus 로고    scopus 로고
    • Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy
    • doi: 10.1158/0008-5472.CAN-08-1735
    • Schulte, J. H., Lim, S., Schramm, A., Friedrichs, N., Koster, J., Versteeg, R., et al. (2009). Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy. Cancer Res. 69, 2065-2071. doi: 10.1158/0008-5472.CAN-08-1735
    • (2009) Cancer Res. , vol.69 , pp. 2065-2071
    • Schulte, J.H.1    Lim, S.2    Schramm, A.3    Friedrichs, N.4    Koster, J.5    Versteeg, R.6
  • 128
    • 38649123072 scopus 로고    scopus 로고
    • Conserved metabolic regulatory functions of sirtuins
    • doi: 10.1016/j.cmet.2007.11.006
    • Schwer, B., and Verdin, E. (2008). Conserved metabolic regulatory functions of sirtuins. Cell Metab. 7, 104-112. doi: 10.1016/j.cmet.2007.11.006
    • (2008) Cell Metab. , vol.7 , pp. 104-112
    • Schwer, B.1    Verdin, E.2
  • 129
    • 84887574192 scopus 로고    scopus 로고
    • 3-dependent chromatin accessibility of early vitamin D receptor target genes
    • doi: 10.1016/j.bbagrm.2013.10.003
    • 3-dependent chromatin accessibility of early vitamin D receptor target genes. Biochim. Biophys. Acta 1829, 1266-1275. doi: 10.1016/j.bbagrm.2013.10.003
    • (2013) Biochim. Biophys. Acta , vol.1829 , pp. 1266-1275
    • Seuter, S.1    Pehkonen, P.2    Heikkinen, S.3    Carlberg, C.4
  • 130
    • 33845611987 scopus 로고    scopus 로고
    • Discovery of novel epigenetic markers in non-Hodgkin's lymphoma
    • doi: 10.1093/carcin/bgl092
    • Shi, H., Guo, J., Duff, D. J., Rahmatpanah, F., Chitima-Matsiga, R., Al-Kuhlani, M., et al. (2007). Discovery of novel epigenetic markers in non-Hodgkin's lymphoma. Carcinogenesis 28, 60-70. doi: 10.1093/carcin/bgl092
    • (2007) Carcinogenesis , vol.28 , pp. 60-70
    • Shi, H.1    Guo, J.2    Duff, D.J.3    Rahmatpanah, F.4    Chitima-Matsiga, R.5    Al-Kuhlani, M.6
  • 131
    • 0036605995 scopus 로고    scopus 로고
    • Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells
    • Shi, H., Yan, P. S., Chen, C. M., Rahmatpanah, F., Lofton-Day, C., Caldwell, C. W., et al. (2002). Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells. Cancer Res. 62, 3214-3220.
    • (2002) Cancer Res. , vol.62 , pp. 3214-3220
    • Shi, H.1    Yan, P.S.2    Chen, C.M.3    Rahmatpanah, F.4    Lofton-Day, C.5    Caldwell, C.W.6
  • 132
    • 11144332565 scopus 로고    scopus 로고
    • Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
    • doi: 10.1016/j.cell.2004.12.012
    • Shi, Y., Lan, F., Matson, C., Mulligan, P., Whetstine, J. R., Cole, P. A., et al. (2004). Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119, 941-953. doi: 10.1016/j.cell.2004.12.012
    • (2004) Cell , vol.119 , pp. 941-953
    • Shi, Y.1    Lan, F.2    Matson, C.3    Mulligan, P.4    Whetstine, J.R.5    Cole, P.A.6
  • 133
    • 33846025127 scopus 로고    scopus 로고
    • Dynamic regulation of histone lysine methylation by demethylases
    • doi: 10.1016/j.molcel.2006.12.010
    • Shi, Y., and Whetstine, J. R. (2007). Dynamic regulation of histone lysine methylation by demethylases. Mol. Cell 25, 1-14. doi: 10.1016/j.molcel.2006.12.010
    • (2007) Mol. Cell , vol.25 , pp. 1-14
    • Shi, Y.1    Whetstine, J.R.2
  • 134
    • 84881184830 scopus 로고    scopus 로고
    • Epigenetic distortion to VDR transcriptional regulation in prostate cancer cells
    • doi: 10.1016/j.jsbmb.2012.10.002
    • Singh, P. K., Doig, C. L., Dhiman, V. K., Turner, B. M., Smiraglia, D. J., and Campbell, M. J. (2013). Epigenetic distortion to VDR transcriptional regulation in prostate cancer cells. J. Steroid Biochem. Mol. Biol. 136, 258-263. doi: 10.1016/j.jsbmb.2012.10.002
    • (2013) J. Steroid Biochem. Mol. Biol. , vol.136 , pp. 258-263
    • Singh, P.K.1    Doig, C.L.2    Dhiman, V.K.3    Turner, B.M.4    Smiraglia, D.J.5    Campbell, M.J.6
  • 135
    • 84891676806 scopus 로고    scopus 로고
    • Global and gene-specific promoter methylation analysis in primary hyperparathyroidism
    • doi: 10.4161/epi.24823
    • Sulaiman, L., Juhlin, C. C., Nilsson, I. L., Fotouhi, O., Larsson, C., and Hashemi, J. (2013). Global and gene-specific promoter methylation analysis in primary hyperparathyroidism. Epigenetics 8, 646-655. doi: 10.4161/epi.24823
    • (2013) Epigenetics , vol.8 , pp. 646-655
    • Sulaiman, L.1    Juhlin, C.C.2    Nilsson, I.L.3    Fotouhi, O.4    Larsson, C.5    Hashemi, J.6
  • 136
    • 34249900454 scopus 로고    scopus 로고
    • The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation
    • doi: 10.1038/nature05823
    • Tahiliani, M., Mei, P., Fang, R., Leonor, T., Rutenberg, M., Shimizu, F., et al. (2007). The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature 447, 601-605. doi: 10.1038/nature05823
    • (2007) Nature , vol.447 , pp. 601-605
    • Tahiliani, M.1    Mei, P.2    Fang, R.3    Leonor, T.4    Rutenberg, M.5    Shimizu, F.6
  • 138
    • 69449102520 scopus 로고    scopus 로고
    • Genome-wide analysis of histone H3 lysine9 modifications in human mesenchymal stem cell osteogenic differentiation
    • doi: 10.1371/journal.pone.0006792
    • Tan, J., Lu, J., Huang, W., Dong, Z., Kong, C., Li, L., et al. (2009). Genome-wide analysis of histone H3 lysine9 modifications in human mesenchymal stem cell osteogenic differentiation. PLoS ONE 4:e6792. doi: 10.1371/journal.pone.0006792
    • (2009) PLoS ONE , vol.4
    • Tan, J.1    Lu, J.2    Huang, W.3    Dong, Z.4    Kong, C.5    Li, L.6
  • 139
    • 84872607594 scopus 로고    scopus 로고
    • Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa
    • doi: 10.1111/acel.12030
    • Tapp, H. S., Commane, D. M., Bradburn, D. M., Arasaradnam, R., Mathers, J. C., Johnson, I. T., et al. (2013). Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa. Aging Cell 12, 148-155. doi: 10.1111/acel.12030
    • (2013) Aging Cell , vol.12 , pp. 148-155
    • Tapp, H.S.1    Commane, D.M.2    Bradburn, D.M.3    Arasaradnam, R.4    Mathers, J.C.5    Johnson, I.T.6
  • 140
    • 33845417885 scopus 로고    scopus 로고
    • The cancer epigenome-components and functional correlates
    • doi: 10.1101/gad.1464906
    • Ting, A. H., McGarvey, K. M., and Baylin, S. B. (2006). The cancer epigenome-components and functional correlates. Genes Dev. 20, 3215-3231. doi: 10.1101/gad.1464906
    • (2006) Genes Dev. , vol.20 , pp. 3215-3231
    • Ting, A.H.1    McGarvey, K.M.2    Baylin, S.B.3
  • 141
    • 79952532412 scopus 로고    scopus 로고
    • Cancer epigenetics: linking basic biology to clinical medicine
    • doi: 10.1038/cr.2011.24
    • Tsai, H. C., and Baylin, S. B. (2011). Cancer epigenetics: linking basic biology to clinical medicine. Cell Res. 21, 502-517. doi: 10.1038/cr.2011.24
    • (2011) Cell Res. , vol.21 , pp. 502-517
    • Tsai, H.C.1    Baylin, S.B.2
  • 142
    • 32844454603 scopus 로고    scopus 로고
    • Histone demethylation by a family of JmjC domain-containing proteins
    • doi: 10.1038/nature04433
    • Tsukada, Y., Fang, J., Erdjument-Bromage, H., Warren, M. E., Borchers, C. H., Tempst, P., et al. (2006). Histone demethylation by a family of JmjC domain-containing proteins. Nature 439, 811-816. doi: 10.1038/nature04433
    • (2006) Nature , vol.439 , pp. 811-816
    • Tsukada, Y.1    Fang, J.2    Erdjument-Bromage, H.3    Warren, M.E.4    Borchers, C.H.5    Tempst, P.6
  • 143
    • 84899411750 scopus 로고    scopus 로고
    • PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion, and anti-migration and -invasion activity of vitamin D
    • doi: 10.1038/onc.2013.123
    • Vanoirbeek, E., Eelen, G., Verlinden, L., Carmeliet, G., Mathieu, C., Bouillon, R., et al. (2014). PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion, and anti-migration and -invasion activity of vitamin D. Oncogene 33, 1904-1911. doi: 10.1038/onc.2013.123
    • (2014) Oncogene , vol.33 , pp. 1904-1911
    • Vanoirbeek, E.1    Eelen, G.2    Verlinden, L.3    Carmeliet, G.4    Mathieu, C.5    Bouillon, R.6
  • 144
    • 84885212131 scopus 로고    scopus 로고
    • Methylation status of the CpG islands in vitamin D and calcium-sensing receptor gene promoters does not explain the reduced gene expressions in parathyroid adenomas
    • doi: 10.1210/jc.2013-1699
    • Varshney, S., Bhadada, S. K., Sachdeva, N., Arya, A. K., Saikia, U. N., Behera, A., et al. (2013). Methylation status of the CpG islands in vitamin D and calcium-sensing receptor gene promoters does not explain the reduced gene expressions in parathyroid adenomas. J. Clin. Endocrinol. Metab. 98, E1631-E1635. doi: 10.1210/jc.2013-1699
    • (2013) J. Clin. Endocrinol. Metab. , vol.98
    • Varshney, S.1    Bhadada, S.K.2    Sachdeva, N.3    Arya, A.K.4    Saikia, U.N.5    Behera, A.6
  • 145
    • 77949873898 scopus 로고    scopus 로고
    • Vitamin D controls T cell antigen receptor signaling and activation of human T cells
    • doi: 10.1038/ni.1851
    • Von Essen, M. R., Kongsbak, M., Schjerling, P., Olgaard, K., Odum, N., and Geisler, C. (2010). Vitamin D controls T cell antigen receptor signaling and activation of human T cells. Nat. Immunol. 11, 344-349. doi: 10.1038/ni.1851
    • (2010) Nat. Immunol. , vol.11 , pp. 344-349
    • Von Essen, M.R.1    Kongsbak, M.2    Schjerling, P.3    Olgaard, K.4    Odum, N.5    Geisler, C.6
  • 146
    • 2442684104 scopus 로고    scopus 로고
    • An evaluation of new criteria for CpG islands in the human genome as gene markers
    • doi: 10.1093/bioinformatics/bth059
    • Wang, Y., and Leung, F. C. (2004). An evaluation of new criteria for CpG islands in the human genome as gene markers. Bioinformatics 20, 1170-1177. doi: 10.1093/bioinformatics/bth059
    • (2004) Bioinformatics , vol.20 , pp. 1170-1177
    • Wang, Y.1    Leung, F.C.2
  • 147
    • 33646124469 scopus 로고    scopus 로고
    • Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases
    • doi: 10.1016/j.cell.2006.03.028
    • Whetstine, J. R., Nottke, A., Lan, F., Huarte, M., Smolikov, S., Chen, Z., et al. (2006). Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. Cell 125, 467-481. doi: 10.1016/j.cell.2006.03.028
    • (2006) Cell , vol.125 , pp. 467-481
    • Whetstine, J.R.1    Nottke, A.2    Lan, F.3    Huarte, M.4    Smolikov, S.5    Chen, Z.6
  • 148
    • 79956302047 scopus 로고    scopus 로고
    • TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
    • doi: 10.1038/nature10066
    • Williams, K., Christensen, J., Pedersen, M. T., Johansen, J. V., Cloos, P. A., Rappsilber, J., et al. (2011). TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473, 343-348. doi: 10.1038/nature10066
    • (2011) Nature , vol.473 , pp. 343-348
    • Williams, K.1    Christensen, J.2    Pedersen, M.T.3    Johansen, J.V.4    Cloos, P.A.5    Rappsilber, J.6
  • 149
    • 33744956666 scopus 로고    scopus 로고
    • Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer
    • doi: 10.1074/jbc.M510023200
    • Wilson, A. J., Byun, D. S., Popova, N., Murray, L. B., L'Italien, K., Sowa, Y., et al. (2006). Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer. J. Biol. Chem. 281, 13548-13558. doi: 10.1074/jbc.M510023200
    • (2006) J. Biol. Chem. , vol.281 , pp. 13548-13558
    • Wilson, A.J.1    Byun, D.S.2    Popova, N.3    Murray, L.B.4    L'Italien, K.5    Sowa, Y.6
  • 150
    • 77954756915 scopus 로고    scopus 로고
    • Epigenetic regulation of vitamin D converting enzymes
    • doi: 10.1016/j.jsbmb.2010.03.056
    • Wjst, M., Heimbeck, I., Kutschke, D., and Pukelsheim, K. (2010). Epigenetic regulation of vitamin D converting enzymes. J. Steroid Biochem. Mol. Biol. 121, 80-83. doi: 10.1016/j.jsbmb.2010.03.056
    • (2010) J. Steroid Biochem. Mol. Biol. , vol.121 , pp. 80-83
    • Wjst, M.1    Heimbeck, I.2    Kutschke, D.3    Pukelsheim, K.4
  • 151
    • 37649023563 scopus 로고    scopus 로고
    • JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer
    • doi: 10.1073/pnas.0700735104
    • Xiang, Y., Zhu, Z., Han, G., Ye, X., Xu, B., Peng, Z., et al. (2007). JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer. Proc. Natl. Acad. Sci. U.S.A. 104, 19226-19231. doi: 10.1073/pnas.0700735104
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 19226-19231
    • Xiang, Y.1    Zhu, Z.2    Han, G.3    Ye, X.4    Xu, B.5    Peng, Z.6
  • 152
    • 84871438065 scopus 로고    scopus 로고
    • Tet1 controls meiosis by regulating meiotic gene expression
    • doi: 10.1038/nature11709
    • Yamaguchi, S., Hong, K., Liu, R., Shen, L., Inoue, A., Diep, D., et al. (2012). Tet1 controls meiosis by regulating meiotic gene expression. Nature 492, 443-447. doi: 10.1038/nature11709
    • (2012) Nature , vol.492 , pp. 443-447
    • Yamaguchi, S.1    Hong, K.2    Liu, R.3    Shen, L.4    Inoue, A.5    Diep, D.6
  • 153
    • 33947244845 scopus 로고    scopus 로고
    • PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation
    • doi: 10.1016/j.molcel.2007.03.001
    • Yamane, K., Tateishi, K., Klose, R. J., Fang, J., Fabrizio, L. A., Erdjument-Bromage, H., et al. (2007). PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. Mol. Cell 25, 801-812. doi: 10.1016/j.molcel.2007.03.001
    • (2007) Mol. Cell , vol.25 , pp. 801-812
    • Yamane, K.1    Tateishi, K.2    Klose, R.J.3    Fang, J.4    Fabrizio, L.A.5    Erdjument-Bromage, H.6
  • 154
    • 70449707918 scopus 로고    scopus 로고
    • Vitamin D for treatment and prevention of infectious diseases: a systematic review of randomized controlled trials
    • doi: 10.4158/EP09101.ORR
    • Yamshchikov, A. V., Desai, N. S., Blumberg, H. M., Ziegler, T. R., and Tangpricha, V. (2009). Vitamin D for treatment and prevention of infectious diseases: a systematic review of randomized controlled trials. Endocr. Pract. 15, 438-449. doi: 10.4158/EP09101.ORR
    • (2009) Endocr. Pract. , vol.15 , pp. 438-449
    • Yamshchikov, A.V.1    Desai, N.S.2    Blumberg, H.M.3    Ziegler, T.R.4    Tangpricha, V.5
  • 155
    • 0021238931 scopus 로고
    • 3 (1,25(OH)2D3) on neoplastic and osteoblastic phenotype in clonal rat osteosarcoma cells
    • doi: 10.1016/0006-291X(84)90748-4
    • 3 (1,25(OH)2D3) on neoplastic and osteoblastic phenotype in clonal rat osteosarcoma cells. Biochem. Biophys. Res. Commun. 121, 796-801. doi: 10.1016/0006-291X(84)90748-4
    • (1984) Biochem. Biophys. Res. Commun. , vol.121 , pp. 796-801
    • Yoneda, T.1    Aya, S.2    Sakuda, M.3
  • 156
    • 33646805365 scopus 로고    scopus 로고
    • Vitamin D receptor is a novel drug target for ovarian cancer treatment
    • doi: 10.2174/156800906776842939
    • Zhang, X., Nicosia, S. V., and Bai, W. (2006). Vitamin D receptor is a novel drug target for ovarian cancer treatment. Curr. Cancer Drug. Targets 6, 229-244. doi: 10.2174/156800906776842939
    • (2006) Curr. Cancer Drug. Targets , vol.6 , pp. 229-244
    • Zhang, X.1    Nicosia, S.V.2    Bai, W.3
  • 157
    • 26244441525 scopus 로고    scopus 로고
    • Quantitation of HDAC1 mRNA expression in invasive carcinoma of the breast*
    • doi: 10.1007/s10549-005-6001-1
    • Zhang, Z., Yamashita, H., Toyama, T., Sugiura, H., Ando, Y., Mita, K., et al. (2005). Quantitation of HDAC1 mRNA expression in invasive carcinoma of the breast*. Breast Cancer Res. Treat. 94, 11-16. doi: 10.1007/s10549-005-6001-1
    • (2005) Breast Cancer Res. Treat. , vol.94 , pp. 11-16
    • Zhang, Z.1    Yamashita, H.2    Toyama, T.3    Sugiura, H.4    Ando, Y.5    Mita, K.6
  • 158
    • 84876681149 scopus 로고    scopus 로고
    • A genome-wide methylation study of severe vitamin D deficiency in African American adolescents
    • doi: 10.1016/j.jpeds.2012.10.059
    • Zhu, H., Wang, X., Shi, H., Su, S., Harshfield, G. A., Gutin, B., et al. (2013). A genome-wide methylation study of severe vitamin D deficiency in African American adolescents. J. Pediatr. 162, 1004-1009.e1001. doi: 10.1016/j.jpeds.2012.10.059
    • (2013) J. Pediatr. , vol.162
    • Zhu, H.1    Wang, X.2    Shi, H.3    Su, S.4    Harshfield, G.A.5    Gutin, B.6
  • 159
    • 2342603414 scopus 로고    scopus 로고
    • Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis
    • doi: 10.1016/S1535-6108(04)00114-X
    • Zhu, P., Martin, E., Mengwasser, J., Schlag, P., Janssen, K. P., and Göttlicher, M. (2004). Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis. Cancer Cell 5, 455-463. doi: 10.1016/S1535-6108(04)00114-X
    • (2004) Cancer Cell , vol.5 , pp. 455-463
    • Zhu, P.1    Martin, E.2    Mengwasser, J.3    Schlag, P.4    Janssen, K.P.5    Göttlicher, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.