-
1
-
-
33746586249
-
Epigenetic corruption of VDR signalling in malignancy
-
Abedin, S. A., Banwell, C. M., Colston, K. W., Carlberg, C., and Campbell, M. J. (2006). Epigenetic corruption of VDR signalling in malignancy. Anticancer Res. 26, 2557-2566.
-
(2006)
Anticancer Res.
, vol.26
, pp. 2557-2566
-
-
Abedin, S.A.1
Banwell, C.M.2
Colston, K.W.3
Carlberg, C.4
Campbell, M.J.5
-
3
-
-
79651473285
-
Vitamin D receptor gene methylation is associated with ethnicity, tuberculosis, and TaqI polymorphism
-
doi: 10.1016/j.humimm.2010.12.010
-
Andraos, C., Koorsen, G., Knight, J. C., and Bornman, L. (2011). Vitamin D receptor gene methylation is associated with ethnicity, tuberculosis, and TaqI polymorphism. Hum. Immunol. 72, 262-268. doi: 10.1016/j.humimm.2010.12.010
-
(2011)
Hum. Immunol.
, vol.72
, pp. 262-268
-
-
Andraos, C.1
Koorsen, G.2
Knight, J.C.3
Bornman, L.4
-
4
-
-
54949104629
-
A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis
-
doi: 10.4161/epi.3.4.6508
-
Arasaradnam, R. P., Commane, D. M., Bradburn, D., and Mathers, J. C. (2008). A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis. Epigenetics 3, 193-198. doi: 10.4161/epi.3.4.6508
-
(2008)
Epigenetics
, vol.3
, pp. 193-198
-
-
Arasaradnam, R.P.1
Commane, D.M.2
Bradburn, D.3
Mathers, J.C.4
-
5
-
-
24744453331
-
Methyl-CpG-binding proteins in cancer: blaming the DNA methylation messenger
-
doi: 10.1139/o05-035
-
Ballestar, E., and Esteller, M. (2005). Methyl-CpG-binding proteins in cancer: blaming the DNA methylation messenger. Biochem. Cell Biol. 83, 374-384. doi: 10.1139/o05-035
-
(2005)
Biochem. Cell Biol.
, vol.83
, pp. 374-384
-
-
Ballestar, E.1
Esteller, M.2
-
6
-
-
33846933274
-
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
-
doi: 10.1038/nature05515
-
Barreto, G., Schafer, A., Marhold, J., Stach, D., Swaminathan, S. K., Handa, V., et al. (2007). Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 445, 671-675. doi: 10.1038/nature05515
-
(2007)
Nature
, vol.445
, pp. 671-675
-
-
Barreto, G.1
Schafer, A.2
Marhold, J.3
Stach, D.4
Swaminathan, S.K.5
Handa, V.6
-
7
-
-
80053144962
-
A decade of exploring the cancer epigenome - biological and translational implications
-
doi: 10.1038/nrc3130
-
Baylin, S. B., and Jones, P. A. (2011). A decade of exploring the cancer epigenome - biological and translational implications. Nat. Rev. Cancer 11, 726-734. doi: 10.1038/nrc3130
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 726-734
-
-
Baylin, S.B.1
Jones, P.A.2
-
8
-
-
23744461983
-
Transposons reanimated in mice
-
doi: 10.1016/j.cell.2005.07.024
-
Bestor, T. H. (2005). Transposons reanimated in mice. Cell 122, 322-325. doi: 10.1016/j.cell.2005.07.024
-
(2005)
Cell
, vol.122
, pp. 322-325
-
-
Bestor, T.H.1
-
9
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
doi: 10.1101/gad.947102
-
Bird, A. (2002). DNA methylation patterns and epigenetic memory. Genes Dev. 16, 6-21. doi: 10.1101/gad.947102
-
(2002)
Genes Dev.
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
10
-
-
0019322245
-
DNA methylation and the frequency of CpG in animal DNA
-
doi: 10.1093/nar/8.7.1499
-
Bird, A. P. (1980). DNA methylation and the frequency of CpG in animal DNA. Nucleic Acids Res. 8, 1499-1504. doi: 10.1093/nar/8.7.1499
-
(1980)
Nucleic Acids Res.
, vol.8
, pp. 1499-1504
-
-
Bird, A.P.1
-
11
-
-
34548131197
-
Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors
-
doi: 10.1093/jnci/djm069
-
Bjornsson, H. T., Brown, L. J., Fallin, M. D., Rongione, M. A., Bibikova, M., Wickham, E., et al. (2007). Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors. J. Natl. Cancer Inst. 99, 1270-1273. doi: 10.1093/jnci/djm069
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 1270-1273
-
-
Bjornsson, H.T.1
Brown, L.J.2
Fallin, M.D.3
Rongione, M.A.4
Bibikova, M.5
Wickham, E.6
-
12
-
-
53849136271
-
Vitamin D and human health: lessons from vitamin D receptor null mice
-
doi: 10.1210/er.2008-0004
-
Bouillon, R., Carmeliet, G., Verlinden, L., Van Etten, E., Verstuyf, A., Luderer, H. F., et al. (2008). Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr. Rev. 29, 726-776. doi: 10.1210/er.2008-0004
-
(2008)
Endocr. Rev.
, vol.29
, pp. 726-776
-
-
Bouillon, R.1
Carmeliet, G.2
Verlinden, L.3
Van Etten, E.4
Verstuyf, A.5
Luderer, H.F.6
-
13
-
-
84855985851
-
Expression and function of the vitamin D receptor in malignant germ cell tumour of the testis
-
Bremmer, F., Thelen, P., Pottek, T., Behnes, C. L., Radzun, H. J., and Schweyer, S. (2012). Expression and function of the vitamin D receptor in malignant germ cell tumour of the testis. Anticancer Res. 32, 341-349.
-
(2012)
Anticancer Res.
, vol.32
, pp. 341-349
-
-
Bremmer, F.1
Thelen, P.2
Pottek, T.3
Behnes, C.L.4
Radzun, H.J.5
Schweyer, S.6
-
14
-
-
40849124009
-
DNA methylation markers and early recurrence in stage I lung cancer
-
doi: 10.1056/NEJMoa0706550
-
Brock, M. V., Hooker, C. M., Ota-Machida, E., Han, Y., Guo, M., Ames, S., et al. (2008). DNA methylation markers and early recurrence in stage I lung cancer. N. Engl. J. Med. 358, 1118-1128. doi: 10.1056/NEJMoa0706550
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1118-1128
-
-
Brock, M.V.1
Hooker, C.M.2
Ota-Machida, E.3
Han, Y.4
Guo, M.5
Ames, S.6
-
15
-
-
0034455926
-
Reduced parathyroid vitamin D receptor messenger ribonucleic acid levels in primary and secondary hyperparathyroidism
-
doi: 10.1210/jc.85.5.2000
-
Carling, T., Rastad, J., Szabó, E., Westin, G., and Akerström, G. (2000). Reduced parathyroid vitamin D receptor messenger ribonucleic acid levels in primary and secondary hyperparathyroidism. J. Clin. Endocrinol. Metab. 85, 2000-2003. doi: 10.1210/jc.85.5.2000
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 2000-2003
-
-
Carling, T.1
Rastad, J.2
Szabó, E.3
Westin, G.4
Akerström, G.5
-
16
-
-
84875677701
-
VDR hypermethylation and HIV-induced T cell loss
-
doi: 10.1189/jlb.0812383
-
Chandel, N., Husain, M., Goel, H., Salhan, D., Lan, X., Malhotra, A., et al. (2013). VDR hypermethylation and HIV-induced T cell loss. J. Leukoc. Biol. 93, 623-631. doi: 10.1189/jlb.0812383
-
(2013)
J. Leukoc. Biol.
, vol.93
, pp. 623-631
-
-
Chandel, N.1
Husain, M.2
Goel, H.3
Salhan, D.4
Lan, X.5
Malhotra, A.6
-
17
-
-
0035676731
-
Expression profile of histone deacetylase 1 in gastric cancer tissues
-
doi: 10.1111/j.1349-7006.2001.tb02153.x
-
Choi, J. H., Kwon, H. J., Yoon, B. I., Kim, J. H., Han, S. U., Joo, H. J., et al. (2001). Expression profile of histone deacetylase 1 in gastric cancer tissues. Jpn. J. Cancer Res. 92, 1300-1304. doi: 10.1111/j.1349-7006.2001.tb02153.x
-
(2001)
Jpn. J. Cancer Res.
, vol.92
, pp. 1300-1304
-
-
Choi, J.H.1
Kwon, H.J.2
Yoon, B.I.3
Kim, J.H.4
Han, S.U.5
Joo, H.J.6
-
18
-
-
33947245128
-
RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3
-
doi: 10.1016/j.cell.2007.02.003
-
Christensen, J., Agger, K., Cloos, P. A., Pasini, D., Rose, S., Sennels, L., et al. (2007). RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3. Cell 128, 1063-1076. doi: 10.1016/j.cell.2007.02.003
-
(2007)
Cell
, vol.128
, pp. 1063-1076
-
-
Christensen, J.1
Agger, K.2
Cloos, P.A.3
Pasini, D.4
Rose, S.5
Sennels, L.6
-
19
-
-
33746332412
-
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
-
doi: 10.1038/nature04837
-
Cloos, P. A., Christensen, J., Agger, K., Maiolica, A., Rappsilber, J., Antal, T., et al. (2006). The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. Nature 442, 307-311. doi: 10.1038/nature04837
-
(2006)
Nature
, vol.442
, pp. 307-311
-
-
Cloos, P.A.1
Christensen, J.2
Agger, K.3
Maiolica, A.4
Rappsilber, J.5
Antal, T.6
-
20
-
-
0037436509
-
Loss of IGF2 imprinting: a potential marker of colorectal cancer risk
-
doi: 10.1126/science.1080902
-
Cui, H., Cruz-Correa, M., Giardiello, F. M., Hutcheon, D. F., Kafonek, D. R., Brandenburg, S., et al. (2003). Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science 299, 1753-1755. doi: 10.1126/science.1080902
-
(2003)
Science
, vol.299
, pp. 1753-1755
-
-
Cui, H.1
Cruz-Correa, M.2
Giardiello, F.M.3
Hutcheon, D.F.4
Kafonek, D.R.5
Brandenburg, S.6
-
21
-
-
84883154469
-
LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer
-
doi: 10.1038/bjc.2013.364
-
Ding, J., Zhang, Z. M., Xia, Y., Liao, G. Q., Pan, Y., Liu, S., et al. (2013). LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer. Br. J. Cancer 109, 994-1003. doi: 10.1038/bjc.2013.364
-
(2013)
Br. J. Cancer
, vol.109
, pp. 994-1003
-
-
Ding, J.1
Zhang, Z.M.2
Xia, Y.3
Liao, G.Q.4
Pan, Y.5
Liu, S.6
-
22
-
-
84873564427
-
Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns
-
doi: 10.1093/carcin/bgs331
-
Doig, C. L., Singh, P. K., Dhiman, V. K., Thorne, J. L., Battaglia, S., Sobolewski, M., et al. (2013). Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns. Carcinogenesis 34, 248-256. doi: 10.1093/carcin/bgs331
-
(2013)
Carcinogenesis
, vol.34
, pp. 248-256
-
-
Doig, C.L.1
Singh, P.K.2
Dhiman, V.K.3
Thorne, J.L.4
Battaglia, S.5
Sobolewski, M.6
-
23
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
doi: 10.1126/science.1083557
-
Eden, A., Gaudet, F., Waghmare, A., and Jaenisch, R. (2003). Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300, 455. doi: 10.1126/science.1083557
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
24
-
-
34547792388
-
Epigenetic gene silencing in cancer: the DNA hypermethylome
-
doi: 10.1093/hmg/ddm018
-
Esteller, M. (2007a). Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum. Mol. Genet. 16, Spec No 1, R50-R59. doi: 10.1093/hmg/ddm018
-
(2007)
Hum. Mol. Genet.
, vol.16
, Issue.SPEC. 1
-
-
Esteller, M.1
-
25
-
-
31444437920
-
Epigenetics provides a new generation of oncogenes and tumour-suppressor genes
-
doi: 10.1038/sj.bjc.6602918
-
Esteller, M. (2007b). Epigenetics provides a new generation of oncogenes and tumour-suppressor genes. Br. J. Cancer 96(Suppl.), R26-R30. doi: 10.1038/sj.bjc.6602918
-
(2007)
Br. J. Cancer
, vol.96
, Issue.SUPPL.
-
-
Esteller, M.1
-
26
-
-
40849139208
-
Epigenetics in cancer
-
doi: 10.1056/NEJMra072067
-
Esteller, M. (2008). Epigenetics in cancer. N. Engl. J. Med. 358, 1148-1159. doi: 10.1056/NEJMra072067
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
27
-
-
0032706744
-
hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis
-
doi: 10.1016/S0002-9440(10)65492-2
-
Esteller, M., Catasus, L., Matias-Guiu, X., Mutter, G. L., Prat, J., Baylin, S. B., et al. (1999). hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis. Am. J. Pathol. 155, 1767-1772. doi: 10.1016/S0002-9440(10)65492-2
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1767-1772
-
-
Esteller, M.1
Catasus, L.2
Matias-Guiu, X.3
Mutter, G.L.4
Prat, J.5
Baylin, S.B.6
-
28
-
-
0036392059
-
DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms
-
doi: 10.1016/S1044-579X(02)00059-7
-
Feinberg, A. P., Cui, H., and Ohlsson, R. (2002). DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms. Semin. Cancer Biol. 12, 389-398. doi: 10.1016/S1044-579X(02)00059-7
-
(2002)
Semin. Cancer Biol.
, vol.12
, pp. 389-398
-
-
Feinberg, A.P.1
Cui, H.2
Ohlsson, R.3
-
29
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
doi: 10.1038/nature10008
-
Ficz, G., Branco, M. R., Seisenberger, S., Santos, F., Krueger, F., Hore, T. A., et al. (2011). Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473, 398-402. doi: 10.1038/nature10008
-
(2011)
Nature
, vol.473
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
Santos, F.4
Krueger, F.5
Hore, T.A.6
-
30
-
-
84891768365
-
Ensembl 2014
-
doi: 10.1093/nar/gkt1196
-
Flicek, P., Amode, M. R., Barrell, D., Beal, K., Billis, K., Brent, S., et al. (2014). Ensembl 2014. Nucleic Acids Res. 42, D749-D755. doi: 10.1093/nar/gkt1196
-
(2014)
Nucleic Acids Res.
, vol.42
-
-
Flicek, P.1
Amode, M.R.2
Barrell, D.3
Beal, K.4
Billis, K.5
Brent, S.6
-
31
-
-
33745146571
-
Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells
-
doi: 10.1101/gad.388206
-
Fodor, B. D., Kubicek, S., Yonezawa, M., O'Sullivan, R. J., Sengupta, R., Perez-Burgos, L., et al. (2006). Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells. Genes Dev. 20, 1557-1562. doi: 10.1101/gad.388206
-
(2006)
Genes Dev.
, vol.20
, pp. 1557-1562
-
-
Fodor, B.D.1
Kubicek, S.2
Yonezawa, M.3
O'Sullivan, R.J.4
Sengupta, R.5
Perez-Burgos, L.6
-
32
-
-
36049022778
-
JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes
-
doi: 10.1038/nature06255
-
Frescas, D., Guardavaccaro, D., Bassermann, F., Koyama-Nasu, R., and Pagano, M. (2007). JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes. Nature 450, 309-313. doi: 10.1038/nature06255
-
(2007)
Nature
, vol.450
, pp. 309-313
-
-
Frescas, D.1
Guardavaccaro, D.2
Bassermann, F.3
Koyama-Nasu, R.4
Pagano, M.5
-
33
-
-
56449126497
-
KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state
-
doi: 10.4161/cc.7.22.7062
-
Frescas, D., Guardavaccaro, D., Kuchay, S. M., Kato, H., Poleshko, A., Basrur, V., et al. (2008). KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state. Cell Cycle 7, 3539-3547. doi: 10.4161/cc.7.22.7062
-
(2008)
Cell Cycle
, vol.7
, pp. 3539-3547
-
-
Frescas, D.1
Guardavaccaro, D.2
Kuchay, S.M.3
Kato, H.4
Poleshko, A.5
Basrur, V.6
-
35
-
-
33846690407
-
Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors
-
doi: 10.1016/j.cell.2006.12.038
-
Garcia-Bassets, I., Kwon, Y. S., Telese, F., Prefontaine, G. G., Hutt, K. R., Cheng, C. S., et al. (2007). Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors. Cell 128, 505-518. doi: 10.1016/j.cell.2006.12.038
-
(2007)
Cell
, vol.128
, pp. 505-518
-
-
Garcia-Bassets, I.1
Kwon, Y.S.2
Telese, F.3
Prefontaine, G.G.4
Hutt, K.R.5
Cheng, C.S.6
-
36
-
-
0023216891
-
CpG islands in vertebrate genomes
-
doi: 10.1016/0022-2836(87)90689-9
-
Gardiner-Garden, M., and Frommer, M. (1987). CpG islands in vertebrate genomes. J. Mol. Biol. 196, 261-282. doi: 10.1016/0022-2836(87)90689-9
-
(1987)
J. Mol. Biol.
, vol.196
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
37
-
-
0642336647
-
Short-chain fatty acids and colon cancer cells: the vitamin D receptor-butyrate connection
-
doi: 10.1007/978-3-642-55580-0_18
-
Gaschott, T., and Stein, J. (2003). Short-chain fatty acids and colon cancer cells: the vitamin D receptor-butyrate connection. Recent Results Cancer Res. 164, 247-257. doi: 10.1007/978-3-642-55580-0_18
-
(2003)
Recent Results Cancer Res.
, vol.164
, pp. 247-257
-
-
Gaschott, T.1
Stein, J.2
-
38
-
-
54349093531
-
HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling
-
doi: 10.4161/cbt.7.10.6561
-
Godman, C. A., Joshi, R., Tierney, B. R., Greenspan, E., Rasmussen, T. P., Wang, H. W., et al. (2008). HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling. Cancer Biol. Ther. 7, 1570-1580. doi: 10.4161/cbt.7.10.6561
-
(2008)
Cancer Biol. Ther.
, vol.7
, pp. 1570-1580
-
-
Godman, C.A.1
Joshi, R.2
Tierney, B.R.3
Greenspan, E.4
Rasmussen, T.P.5
Wang, H.W.6
-
39
-
-
0031042732
-
Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism
-
doi: 10.1038/ki.1997.41
-
Gogusev, J., Duchambon, P., Hory, B., Giovannini, M., Goureau, Y., Sarfati, E., et al. (1997). Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism. Kidney Int. 51, 328-336. doi: 10.1038/ki.1997.41
-
(1997)
Kidney Int.
, vol.51
, pp. 328-336
-
-
Gogusev, J.1
Duchambon, P.2
Hory, B.3
Giovannini, M.4
Goureau, Y.5
Sarfati, E.6
-
40
-
-
84859893371
-
Histone methylation: a dynamic mark in health, disease and inheritance
-
doi: 10.1038/nrg3173
-
Greer, E. L., and Shi, Y. (2012). Histone methylation: a dynamic mark in health, disease and inheritance. Nat. Rev. Genet. 13, 343-357. doi: 10.1038/nrg3173
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 343-357
-
-
Greer, E.L.1
Shi, Y.2
-
41
-
-
0024365892
-
Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
-
doi: 10.1007/BF00286709
-
Greger, V., Passarge, E., Höpping, W., Messmer, E., and Horsthemke, B. (1989). Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet. 83, 155-158. doi: 10.1007/BF00286709
-
(1989)
Hum. Genet.
, vol.83
, pp. 155-158
-
-
Greger, V.1
Passarge, E.2
Höpping, W.3
Messmer, E.4
Horsthemke, B.5
-
42
-
-
0019875880
-
Methylation of CpG sequences in eukaryotic DNA
-
doi: 10.1016/0014-5793(81)80055-5
-
Gruenbaum, Y., Stein, R., Cedar, H., and Razin, A. (1981). Methylation of CpG sequences in eukaryotic DNA. FEBS Lett. 124, 67-71. doi: 10.1016/0014-5793(81)80055-5
-
(1981)
FEBS Lett.
, vol.124
, pp. 67-71
-
-
Gruenbaum, Y.1
Stein, R.2
Cedar, H.3
Razin, A.4
-
43
-
-
33845868198
-
Sirtuins as potential targets for metabolic syndrome
-
doi: 10.1038/nature05486
-
Guarente, L. (2006). Sirtuins as potential targets for metabolic syndrome. Nature 444, 868-874. doi: 10.1038/nature05486
-
(2006)
Nature
, vol.444
, pp. 868-874
-
-
Guarente, L.1
-
44
-
-
79951777299
-
Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells
-
doi: 10.1186/1471-2407-11-81
-
Habano, W., Gamo, T., Terashima, J., Sugai, T., Otsuka, K., Wakabayashi, G., et al. (2011). Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells. BMC Cancer 11:81. doi: 10.1186/1471-2407-11-81
-
(2011)
BMC Cancer
, vol.11
, pp. 81
-
-
Habano, W.1
Gamo, T.2
Terashima, J.3
Sugai, T.4
Otsuka, K.5
Wakabayashi, G.6
-
45
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
-
doi: 10.1038/nrg2485
-
Haberland, M., Montgomery, R. L., and Olson, E. N. (2009). The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat. Rev. Genet. 10, 32-42. doi: 10.1038/nrg2485
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
-
46
-
-
84872770694
-
Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine
-
doi: 10.1126/science.1229277
-
Hackett, J. A., Sengupta, R., Zylicz, J. J., Murakami, K., Lee, C., Down, T. A., et al. (2013). Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine. Science 339, 448-452. doi: 10.1126/science.1229277
-
(2013)
Science
, vol.339
, pp. 448-452
-
-
Hackett, J.A.1
Sengupta, R.2
Zylicz, J.J.3
Murakami, K.4
Lee, C.5
Down, T.A.6
-
47
-
-
1842631408
-
Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer
-
doi: 10.1002/pros.20022
-
Halkidou, K., Gaughan, L., Cook, S., Leung, H. Y., Neal, D. E., and Robson, C. N. (2004). Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer. Prostate 59, 177-189. doi: 10.1002/pros.20022
-
(2004)
Prostate
, vol.59
, pp. 177-189
-
-
Halkidou, K.1
Gaughan, L.2
Cook, S.3
Leung, H.Y.4
Neal, D.E.5
Robson, C.N.6
-
48
-
-
33947278277
-
In silico analysis of the 5' region of the Vitamin D receptor gene: functional implications of evolutionary conservation
-
doi: 10.1016/j.jsbmb.2006.12.046
-
Halsall, J. A., Osborne, J. E., Hutchinson, P. E., and Pringle, J. H. (2007). In silico analysis of the 5' region of the Vitamin D receptor gene: functional implications of evolutionary conservation. J. Steroid. Biochem. Mol. Biol. 103, 352-356. doi: 10.1016/j.jsbmb.2006.12.046
-
(2007)
J. Steroid. Biochem. Mol. Biol.
, vol.103
, pp. 352-356
-
-
Halsall, J.A.1
Osborne, J.E.2
Hutchinson, P.E.3
Pringle, J.H.4
-
49
-
-
84873710626
-
Molecular mechanisms of vitamin D action
-
doi: 10.1007/s00223-012-9619-0
-
Haussler, M. R., Whitfield, G. K., Kaneko, I., Haussler, C. A., Hsieh, D., Hsieh, J. C., et al. (2013). Molecular mechanisms of vitamin D action. Calcif. Tissue Int. 92, 77-98. doi: 10.1007/s00223-012-9619-0
-
(2013)
Calcif. Tissue Int.
, vol.92
, pp. 77-98
-
-
Haussler, M.R.1
Whitfield, G.K.2
Kaneko, I.3
Haussler, C.A.4
Hsieh, D.5
Hsieh, J.C.6
-
50
-
-
0024003456
-
A direct link between core histone acetylation and transcriptionally active chromatin
-
Hebbes, T. R., Thorne, A. W., and Crane-Robinson, C. (1988). A direct link between core histone acetylation and transcriptionally active chromatin. EMBO J. 7, 1395-1402.
-
(1988)
EMBO J.
, vol.7
, pp. 1395-1402
-
-
Hebbes, T.R.1
Thorne, A.W.2
Crane-Robinson, C.3
-
51
-
-
84886808679
-
Chromatin proteins and modifications as drug targets
-
doi: 10.1038/nature12751
-
Helin, K., and Dhanak, D. (2013). Chromatin proteins and modifications as drug targets. Nature 502, 480-488. doi: 10.1038/nature12751
-
(2013)
Nature
, vol.502
, pp. 480-488
-
-
Helin, K.1
Dhanak, D.2
-
52
-
-
3042687453
-
Regulation of gene expression by the CYP27B1 promoter-study of a transgenic mouse model
-
doi: 10.1016/j.jsbmb.2004.03.093.
-
Hendrix, I., Anderson, P., May, B., and Morris, H. (2004). Regulation of gene expression by the CYP27B1 promoter-study of a transgenic mouse model. J. Steroid Biochem. Mol. Biol. 89-90, 139-142. doi: 10.1016/j.jsbmb.2004.03.093
-
(2004)
J. Steroid Biochem. Mol. Biol.
, vol.89-90
, pp. 139-142
-
-
Hendrix, I.1
Anderson, P.2
May, B.3
Morris, H.4
-
53
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
doi: 10.1056/NEJMra023075
-
Herman, J. G., and Baylin, S. B. (2003). Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 349, 2042-2054. doi: 10.1056/NEJMra023075
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
55
-
-
84879954055
-
Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer
-
doi: 10.1002/ijc.28143
-
Höbaus, J., Hummel, D. M., Thiem, U., Fetahu, I. S., Aggarwal, A., Müllauer, L., et al. (2013b). Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer. Int. J. Cancer 133, 1380-1388. doi: 10.1002/ijc.28143
-
(2013)
Int. J. Cancer
, vol.133
, pp. 1380-1388
-
-
Höbaus, J.1
Hummel, D.M.2
Thiem, U.3
Fetahu, I.S.4
Aggarwal, A.5
Müllauer, L.6
-
56
-
-
84878247928
-
Role of calcium, vitamin d, and the extrarenal vitamin d hydroxylases in carcinogenesis
-
doi: 10.2174/187152013804487434
-
Hobaus, J., Thiem, U., Hummel, D. M., and Kallay, E. (2013). Role of calcium, vitamin d, and the extrarenal vitamin d hydroxylases in carcinogenesis. Anticancer Agents Med. Chem. 13, 20-35. doi: 10.2174/187152013804487434
-
(2013)
Anticancer Agents Med. Chem.
, vol.13
, pp. 20-35
-
-
Hobaus, J.1
Thiem, U.2
Hummel, D.M.3
Kallay, E.4
-
57
-
-
84869044855
-
Epigenetic methylation of parathyroid CaR and VDR promoters in experimental secondary hyperparathyroidism
-
doi: 10.1155/2012/123576
-
Hofman-Bang, J., Gravesen, E., Olgaard, K., and Lewin, E. (2012). Epigenetic methylation of parathyroid CaR and VDR promoters in experimental secondary hyperparathyroidism. Int. J. Nephrol. 2012:123576. doi: 10.1155/2012/123576
-
(2012)
Int. J. Nephrol.
, vol.2012
, pp. 123576
-
-
Hofman-Bang, J.1
Gravesen, E.2
Olgaard, K.3
Lewin, E.4
-
58
-
-
33947302685
-
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases
-
doi: 10.1016/j.cell.2007.02.017
-
Iwase, S., Lan, F., Bayliss, P., De La Torre-Ubieta, L., Huarte, M., Qi, H. H., et al. (2007). The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell 128, 1077-1088. doi: 10.1016/j.cell.2007.02.017
-
(2007)
Cell
, vol.128
, pp. 1077-1088
-
-
Iwase, S.1
Lan, F.2
Bayliss, P.3
De La Torre-Ubieta, L.4
Huarte, M.5
Qi, H.H.6
-
59
-
-
0346220267
-
3 in ovarian cancer cells mediated through the induction of GADD45 via an exonic enhancer
-
doi: 10.1074/jbc.M308430200
-
3 in ovarian cancer cells mediated through the induction of GADD45 via an exonic enhancer. J. Biol. Chem. 278, 48030-48040. doi: 10.1074/jbc.M308430200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48030-48040
-
-
Jiang, F.1
Li, P.2
Fornace, A.J.3
Nicosia, S.V.4
Bai, W.5
-
60
-
-
84869046975
-
DNA methyltransferases, DNA damage repair, and cancer
-
doi: 10.1007/978-1-4419-9967-2_1
-
Jin, B., and Robertson, K. D. (2013). DNA methyltransferases, DNA damage repair, and cancer. Adv. Exp. Med. Biol. 754, 3-29. doi: 10.1007/978-1-4419-9967-2_1
-
(2013)
Adv. Exp. Med. Biol.
, vol.754
, pp. 3-29
-
-
Jin, B.1
Robertson, K.D.2
-
61
-
-
77954761786
-
Epigenetic silencing of CYP24 in the tumor microenvironment
-
doi: 10.1016/j.jsbmb.2010.03.046
-
Johnson, C. S., Chung, I., and Trump, D. L. (2010). Epigenetic silencing of CYP24 in the tumor microenvironment. J. Steroid Biochem. Mol. Biol. 121, 338-342. doi: 10.1016/j.jsbmb.2010.03.046
-
(2010)
J. Steroid Biochem. Mol. Biol.
, vol.121
, pp. 338-342
-
-
Johnson, C.S.1
Chung, I.2
Trump, D.L.3
-
62
-
-
33847065486
-
The epigenomics of cancer
-
doi: 10.1016/j.cell.2007.01.029
-
Jones, P. A., and Baylin, S. B. (2007). The epigenomics of cancer. Cell 128, 683-692. doi: 10.1016/j.cell.2007.01.029
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
63
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
doi: 10.1038/561
-
Jones, P. L., Veenstra, G. J., Wade, P. A., Vermaak, D., Kass, S. U., Landsberger, N., et al. (1998). Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat. Genet. 19, 187-191. doi: 10.1038/561
-
(1998)
Nat. Genet.
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
Veenstra, G.J.2
Wade, P.A.3
Vermaak, D.4
Kass, S.U.5
Landsberger, N.6
-
64
-
-
71549154751
-
Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer
-
doi: 10.1111/j.1600-079X.2009.00729.x
-
Jung-Hynes, B., Reiter, R. J., and Ahmad, N. (2010). Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer. J. Pineal Res. 48, 9-19. doi: 10.1111/j.1600-079X.2009.00729.x
-
(2010)
J. Pineal Res.
, vol.48
, pp. 9-19
-
-
Jung-Hynes, B.1
Reiter, R.J.2
Ahmad, N.3
-
65
-
-
33845762289
-
Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence
-
doi: 10.1158/0008-5472.CAN-06-1570
-
Kahl, P., Gullotti, L., Heukamp, L. C., Wolf, S., Friedrichs, N., Vorreuther, R., et al. (2006). Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence. Cancer Res. 66, 11341-11347. doi: 10.1158/0008-5472.CAN-06-1570
-
(2006)
Cancer Res.
, vol.66
, pp. 11341-11347
-
-
Kahl, P.1
Gullotti, L.2
Heukamp, L.C.3
Wolf, S.4
Friedrichs, N.5
Vorreuther, R.6
-
66
-
-
80051622767
-
Impact of vitamin D metabolism on clinical epigenetics
-
doi: 10.1007/s13148-011-0021-y
-
Karlic, H., and Varga, F. (2011). Impact of vitamin D metabolism on clinical epigenetics. Clin. Epigenetics 2, 55-61. doi: 10.1007/s13148-011-0021-y
-
(2011)
Clin. Epigenetics
, vol.2
, pp. 55-61
-
-
Karlic, H.1
Varga, F.2
-
67
-
-
84891771466
-
The UCSC Genome Browser database: 2014 update
-
doi: 10.1093/nar/gkt1168
-
Karolchik, D., Barber, G. P., Casper, J., Clawson, H., Cline, M. S., Diekhans, M., et al. (2014). The UCSC Genome Browser database: 2014 update. Nucleic Acids Res. 42, D764-770. doi: 10.1093/nar/gkt1168
-
(2014)
Nucleic Acids Res.
, vol.42
-
-
Karolchik, D.1
Barber, G.P.2
Casper, J.3
Clawson, H.4
Cline, M.S.5
Diekhans, M.6
-
68
-
-
0019485450
-
3 1 alpha-hydroxylase and 24-hydroxylase along the rat nephron
-
doi: 10.1073/pnas.78.2.1199
-
3 1 alpha-hydroxylase and 24-hydroxylase along the rat nephron. Proc. Natl. Acad. Sci. U.S.A. 78, 1199-1203. doi: 10.1073/pnas.78.2.1199
-
(1981)
Proc. Natl. Acad. Sci. U.S.A.
, vol.78
, pp. 1199-1203
-
-
Kawashima, H.1
Torikai, S.2
Kurokawa, K.3
-
69
-
-
18044385966
-
Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells
-
doi: 10.1016/j.jsbmb.2004.12.022
-
Khorchide, M., Lechner, D., and Cross, H. S. (2005). Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells. J. Steroid Biochem. Mol. Biol. 93, 167-172. doi: 10.1016/j.jsbmb.2004.12.022
-
(2005)
J. Steroid Biochem. Mol. Biol.
, vol.93
, pp. 167-172
-
-
Khorchide, M.1
Lechner, D.2
Cross, H.S.3
-
70
-
-
0036683055
-
Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases
-
doi: 10.1093/emboj/cdf401
-
Kim, G. D., Ni, J., Kelesoglu, N., Roberts, R. J., and Pradhan, S. (2002). Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases. EMBO J. 21, 4183-4195. doi: 10.1093/emboj/cdf401
-
(2002)
EMBO J.
, vol.21
, pp. 4183-4195
-
-
Kim, G.D.1
Ni, J.2
Kelesoglu, N.3
Roberts, R.J.4
Pradhan, S.5
-
71
-
-
33847043095
-
1alpha,25(OH)2D3-induced DNA methylation suppresses the human CYP27B1 gene
-
doi: 10.1016/j.mce.2006.12.014.
-
Kim, M. S., Fujiki, R., Kitagawa, H., and Kato, S. (2007a). 1alpha,25(OH)2D3-induced DNA methylation suppresses the human CYP27B1 gene. Mol. Cell Endocrinol. 265-266, 168-173. doi: 10.1016/j.mce.2006.12.014
-
(2007)
Mol. Cell Endocrinol
, vol.265-266
, pp. 168-173
-
-
Kim, M.S.1
Fujiki, R.2
Kitagawa, H.3
Kato, S.4
-
72
-
-
33846658748
-
1Alpha,25(OH)2D3-induced transrepression by vitamin D receptor through E-box-type elements in the human parathyroid hormone gene promoter
-
doi: 10.1210/me.2006-0231
-
Kim, M. S., Fujiki, R., Murayama, A., Kitagawa, H., Yamaoka, K., Yamamoto, Y., et al. (2007b). 1Alpha,25(OH)2D3-induced transrepression by vitamin D receptor through E-box-type elements in the human parathyroid hormone gene promoter. Mol. Endocrinol. 21, 334-342. doi: 10.1210/me.2006-0231
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 334-342
-
-
Kim, M.S.1
Fujiki, R.2
Murayama, A.3
Kitagawa, H.4
Yamaoka, K.5
Yamamoto, Y.6
-
73
-
-
40549094047
-
Predicting DNA methylation susceptibility using CpG flanking sequences
-
Kim, S., Li, M., Paik, H., Nephew, K., Shi, H., Kramer, R., et al. (2008). Predicting DNA methylation susceptibility using CpG flanking sequences. Pac. Symp. Biocomput. 13, 315-326.
-
(2008)
Pac. Symp. Biocomput.
, vol.13
, pp. 315-326
-
-
Kim, S.1
Li, M.2
Paik, H.3
Nephew, K.4
Shi, H.5
Kramer, R.6
-
74
-
-
33745847680
-
The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36
-
doi: 10.1038/nature04853
-
Klose, R. J., Yamane, K., Bae, Y., Zhang, D., Erdjument-Bromage, H., Tempst, P., et al. (2006). The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature 442, 312-316. doi: 10.1038/nature04853
-
(2006)
Nature
, vol.442
, pp. 312-316
-
-
Klose, R.J.1
Yamane, K.2
Bae, Y.3
Zhang, D.4
Erdjument-Bromage, H.5
Tempst, P.6
-
75
-
-
33847401344
-
The retinoblastoma binding protein RBP2 is an H3K4 demethylase
-
doi: 10.1016/j.cell.2007.02.013
-
Klose, R. J., Yan, Q., Tothova, Z., Yamane, K., Erdjument-Bromage, H., Tempst, P., et al. (2007). The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell 128, 889-900. doi: 10.1016/j.cell.2007.02.013
-
(2007)
Cell
, vol.128
, pp. 889-900
-
-
Klose, R.J.1
Yan, Q.2
Tothova, Z.3
Yamane, K.4
Erdjument-Bromage, H.5
Tempst, P.6
-
76
-
-
33847076849
-
Chromatin modifications and their function
-
doi: 10.1016/j.cell.2007.02.005
-
Kouzarides, T. (2007). Chromatin modifications and their function. Cell 128, 693-705. doi: 10.1016/j.cell.2007.02.005
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
77
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
doi: 10.1126/science.1169786
-
Kriaucionis, S., and Heintz, N. (2009). The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324, 929-930. doi: 10.1126/science.1169786
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
78
-
-
0037383786
-
The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene
-
doi: 10.1128/MCB.23.8.2669-2679.2003
-
Lagger, G., Doetzlhofer, A., Schuettengruber, B., Haidweger, E., Simboeck, E., Tischler, J., et al. (2003). The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene. Mol. Cell Biol. 23, 2669-2679. doi: 10.1128/MCB.23.8.2669-2679.2003
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 2669-2679
-
-
Lagger, G.1
Doetzlhofer, A.2
Schuettengruber, B.3
Haidweger, E.4
Simboeck, E.5
Tischler, J.6
-
79
-
-
0035099604
-
Transcriptional coregulators of the nuclear receptor superfamily: coactivators and corepressors
-
doi: 10.1007/PL00000856
-
Lee, J. W., Lee, Y. C., Na, S. Y., Jung, D. J., and Lee, S. K. (2001). Transcriptional coregulators of the nuclear receptor superfamily: coactivators and corepressors. Cell Mol. Life Sci. 58, 289-297. doi: 10.1007/PL00000856
-
(2001)
Cell Mol. Life Sci.
, vol.58
, pp. 289-297
-
-
Lee, J.W.1
Lee, Y.C.2
Na, S.Y.3
Jung, D.J.4
Lee, S.K.5
-
80
-
-
0036066178
-
Persistent downregulation of calcium-sensing receptor mRNA in rat parathyroids when severe secondary hyperparathyroidism is reversed by an isogenic kidney transplantation
-
doi: 10.1097/01.ASN.0000024439.38838.03
-
Lewin, E., Garfia, B., Recio, F. L., Rodriguez, M., and Olgaard, K. (2002). Persistent downregulation of calcium-sensing receptor mRNA in rat parathyroids when severe secondary hyperparathyroidism is reversed by an isogenic kidney transplantation. J. Am. Soc. Nephrol. 13, 2110-2116. doi: 10.1097/01.ASN.0000024439.38838.03
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 2110-2116
-
-
Lewin, E.1
Garfia, B.2
Recio, F.L.3
Rodriguez, M.4
Olgaard, K.5
-
81
-
-
84894088172
-
Hypermethylation of the CDKN2A gene promoter is a frequent epigenetic change in periocular sebaceous carcinoma and is associated with younger patient age
-
doi: 10.1016/j.humpath.2013.10.019
-
Liau, J. Y., Liao, S. L., Hsiao, C. H., Lin, M. C., Chang, H. C., and Kuo, K. T. (2014). Hypermethylation of the CDKN2A gene promoter is a frequent epigenetic change in periocular sebaceous carcinoma and is associated with younger patient age. Hum Pathol. 45, 533-539. doi: 10.1016/j.humpath.2013.10.019
-
(2014)
Hum Pathol.
, vol.45
, pp. 533-539
-
-
Liau, J.Y.1
Liao, S.L.2
Hsiao, C.H.3
Lin, M.C.4
Chang, H.C.5
Kuo, K.T.6
-
82
-
-
56849114113
-
Heterochromatin protein 1a stimulates histone H3 lysine 36 demethylation by the Drosophila KDM4A demethylase
-
doi: 10.1016/j.molcel.2008.11.008
-
Lin, C. H., Li, B., Swanson, S., Zhang, Y., Florens, L., Washburn, M. P., et al. (2008). Heterochromatin protein 1a stimulates histone H3 lysine 36 demethylation by the Drosophila KDM4A demethylase. Mol. Cell 32, 696-706. doi: 10.1016/j.molcel.2008.11.008
-
(2008)
Mol. Cell
, vol.32
, pp. 696-706
-
-
Lin, C.H.1
Li, B.2
Swanson, S.3
Zhang, Y.4
Florens, L.5
Washburn, M.P.6
-
83
-
-
84878791222
-
Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer
-
doi: 10.1002/path.4179
-
Lin, Y. W., Ren, L. L., Xiong, H., Du, W., Yu, Y. N., Sun, T. T., et al. (2013). Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer. J. Pathol. 230, 277-290. doi: 10.1002/path.4179
-
(2013)
J. Pathol.
, vol.230
, pp. 277-290
-
-
Lin, Y.W.1
Ren, L.L.2
Xiong, H.3
Du, W.4
Yu, Y.N.5
Sun, T.T.6
-
84
-
-
33746228121
-
Sirtuins in aging and age-related disease
-
doi: 10.1016/j.cell.2006.07.002
-
Longo, V. D., and Kennedy, B. K. (2006). Sirtuins in aging and age-related disease. Cell 126, 257-268. doi: 10.1016/j.cell.2006.07.002
-
(2006)
Cell
, vol.126
, pp. 257-268
-
-
Longo, V.D.1
Kennedy, B.K.2
-
86
-
-
0038748632
-
A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer
-
doi: 10.1074/jbc.274.22.15633
-
Lu, P. J., Sundquist, K., Baeckstrom, D., Poulsom, R., Hanby, A., Meier-Ewert, S., et al. (1999). A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer. J. Biol. Chem. 274, 15633-15645. doi: 10.1074/jbc.274.22.15633
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15633-15645
-
-
Lu, P.J.1
Sundquist, K.2
Baeckstrom, D.3
Poulsom, R.4
Hanby, A.5
Meier-Ewert, S.6
-
87
-
-
77955037065
-
Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer
-
doi: 10.1158/0008-5472.CAN-10-0617
-
Luo, W., Karpf, A. R., Deeb, K. K., Muindi, J. R., Morrison, C. D., Johnson, C. S., et al. (2010). Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer. Cancer Res. 70, 5953-5962. doi: 10.1158/0008-5472.CAN-10-0617
-
(2010)
Cancer Res.
, vol.70
, pp. 5953-5962
-
-
Luo, W.1
Karpf, A.R.2
Deeb, K.K.3
Muindi, J.R.4
Morrison, C.D.5
Johnson, C.S.6
-
88
-
-
77954388100
-
DNA methylation-related vitamin D receptor insensitivity in breast cancer
-
doi: 10.4161/cbt.10.1.11994
-
Marik, R., Fackler, M., Gabrielson, E., Zeiger, M. A., Sukumar, S., Stearns, V., et al. (2010). DNA methylation-related vitamin D receptor insensitivity in breast cancer. Cancer Biol. Ther. 10, 44-53. doi: 10.4161/cbt.10.1.11994
-
(2010)
Cancer Biol. Ther.
, vol.10
, pp. 44-53
-
-
Marik, R.1
Fackler, M.2
Gabrielson, E.3
Zeiger, M.A.4
Sukumar, S.5
Stearns, V.6
-
89
-
-
0035755974
-
Histone deacetylases and cancer: causes and therapies
-
doi: 10.1038/35106079
-
Marks, P., Rifkind, R. A., Richon, V. M., Breslow, R., Miller, T., and Kelly, W. K. (2001). Histone deacetylases and cancer: causes and therapies. Nat. Rev. Cancer 1, 194-202. doi: 10.1038/35106079
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 194-202
-
-
Marks, P.1
Rifkind, R.A.2
Richon, V.M.3
Breslow, R.4
Miller, T.5
Kelly, W.K.6
-
90
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
doi: 10.1038/nature07107
-
Meissner, A., Mikkelsen, T. S., Gu, H., Wernig, M., Hanna, J., Sivachenko, A., et al. (2008). Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454, 766-770. doi: 10.1038/nature07107
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
Wernig, M.4
Hanna, J.5
Sivachenko, A.6
-
91
-
-
24144462170
-
LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription
-
doi: 10.1038/nature04020
-
Metzger, E., Wissmann, M., Yin, N., Müller, J. M., Schneider, R., Peters, A. H., et al. (2005). LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature 437, 436-439. doi: 10.1038/nature04020
-
(2005)
Nature
, vol.437
, pp. 436-439
-
-
Metzger, E.1
Wissmann, M.2
Yin, N.3
Müller, J.M.4
Schneider, R.5
Peters, A.H.6
-
92
-
-
84906791289
-
3 induced histone profiles guide discovery of VDR action sites
-
doi: 10.1016/j.jsbmb.2013.09.005. [Epub ahead of print].
-
3 induced histone profiles guide discovery of VDR action sites. J. Steroid Biochem. Mol. Biol. doi: 10.1016/j.jsbmb.2013.09.005. [Epub ahead of print].
-
(2013)
J. Steroid Biochem. Mol. Biol.
-
-
Meyer, M.B.1
Benkusky, N.A.2
Pike, J.W.3
-
93
-
-
0030768388
-
3 receptor in bone, lung, and other cancers
-
doi: 10.1002/(SICI)1098-2744(199708)19:4<254::AID-MC6>3.0.CO;2-C
-
3 receptor in bone, lung, and other cancers. Mol. Carcinog. 19, 254-257. doi: 10.1002/(SICI)1098-2744(199708)19:4<254::AID-MC6>3.0.CO;2-C
-
(1997)
Mol. Carcinog.
, vol.19
, pp. 254-257
-
-
Miller, C.W.1
Morosetti, R.2
Campbell, M.J.3
Mendoza, S.4
Koeffler, H.P.5
-
94
-
-
77953644347
-
Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases
-
doi: 10.1146/annurev.biochem.78.070907.103946
-
Mosammaparast, N., and Shi, Y. (2010). Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases. Annu. Rev. Biochem. 79, 155-179. doi: 10.1146/annurev.biochem.78.070907.103946
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 155-179
-
-
Mosammaparast, N.1
Shi, Y.2
-
95
-
-
58249096131
-
HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism
-
doi: 10.1038/onc.2008.371
-
Mottet, D., Pirotte, S., Lamour, V., Hagedorn, M., Javerzat, S., Bikfalvi, A., et al. (2009). HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism. Oncogene 28, 243-256. doi: 10.1038/onc.2008.371
-
(2009)
Oncogene
, vol.28
, pp. 243-256
-
-
Mottet, D.1
Pirotte, S.2
Lamour, V.3
Hagedorn, M.4
Javerzat, S.5
Bikfalvi, A.6
-
96
-
-
2342623470
-
Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching
-
doi: 10.1038/sj.emboj.7600157
-
Murayama, A., Kim, M. S., Yanagisawa, J., Takeyama, K., and Kato, S. (2004). Transrepression by a liganded nuclear receptor via a bHLH activator through co-regulator switching. EMBO J. 23, 1598-1608. doi: 10.1038/sj.emboj.7600157
-
(2004)
EMBO J.
, vol.23
, pp. 1598-1608
-
-
Murayama, A.1
Kim, M.S.2
Yanagisawa, J.3
Takeyama, K.4
Kato, S.5
-
97
-
-
23744437421
-
Noncalcemic actions of vitamin D receptor ligands
-
doi: 10.1210/er.2004-0002
-
Nagpal, S., Na, S., and Rathnachalam, R. (2005). Noncalcemic actions of vitamin D receptor ligands. Endocr. Rev. 26, 662-687. doi: 10.1210/er.2004-0002
-
(2005)
Endocr. Rev.
, vol.26
, pp. 662-687
-
-
Nagpal, S.1
Na, S.2
Rathnachalam, R.3
-
98
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
doi: 10.1038/30764
-
Nan, X., Ng, H. H., Johnson, C. A., Laherty, C. D., Turner, B. M., Eisenman, R. N., et al. (1998). Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393, 386-389. doi: 10.1038/30764
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
-
99
-
-
77957110074
-
Vitamin D nutritional policy needs a vision for the future
-
doi: 10.1258/ebm.2010.010014
-
Norman, A. W., and Bouillon, R. (2010). Vitamin D nutritional policy needs a vision for the future. Exp. Biol. Med. (Maywood) 235, 1034-1045. doi: 10.1258/ebm.2010.010014
-
(2010)
Exp. Biol. Med. (Maywood)
, vol.235
, pp. 1034-1045
-
-
Norman, A.W.1
Bouillon, R.2
-
100
-
-
67649344487
-
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface
-
doi: 10.1074/jbc.M809542200
-
Novakovic, B., Sibson, M., Ng, H. K., Manuelpillai, U., Rakyan, V., Down, T., et al. (2009). Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface. J. Biol. Chem. 284, 14838-14848. doi: 10.1074/jbc.M809542200
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 14838-14848
-
-
Novakovic, B.1
Sibson, M.2
Ng, H.K.3
Manuelpillai, U.4
Rakyan, V.5
Down, T.6
-
101
-
-
0041317202
-
Extensive methylation of CpG island of CYP24 gene in osteoblastic ROS17/2.8 cells
-
doi: 10.1093/nass/2.1.249.
-
Ohyama, Y., Kusada, T., Yamasaki, T., and Ide, H. (2002). Extensive methylation of CpG island of CYP24 gene in osteoblastic ROS17/2.8 cells. Nucleic Acids Res. Suppl. 249-250. doi: 10.1093/nass/2.1.249
-
(2002)
Nucleic Acids Res. Suppl.
, pp. 249-250
-
-
Ohyama, Y.1
Kusada, T.2
Yamasaki, T.3
Ide, H.4
-
102
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
doi: 10.1016/S0092-8674(00)81656-6
-
Okano, M., Bell, D. W., Haber, D. A., and Li, E. (1999). DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257. doi: 10.1016/S0092-8674(00)81656-6
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
103
-
-
0031860739
-
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
-
doi: 10.1038/890
-
Okano, M., Xie, S., and Li, E. (1998). Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet. 19, 219-220. doi: 10.1038/890
-
(1998)
Nat. Genet.
, vol.19
, pp. 219-220
-
-
Okano, M.1
Xie, S.2
Li, E.3
-
104
-
-
84880600170
-
MicroRNA-627 mediates the epigenetic mechanisms of vitamin D to suppress proliferation of human colorectal cancer cells and growth of xenograft tumors in mice
-
doi: 10.1053/j.gastro.2013.04.012
-
Padi, S. K., Zhang, Q., Rustum, Y. M., Morrison, C., and Guo, B. (2013). MicroRNA-627 mediates the epigenetic mechanisms of vitamin D to suppress proliferation of human colorectal cancer cells and growth of xenograft tumors in mice. Gastroenterology 145, 437-446. doi: 10.1053/j.gastro.2013.04.012
-
(2013)
Gastroenterology
, vol.145
, pp. 437-446
-
-
Padi, S.K.1
Zhang, Q.2
Rustum, Y.M.3
Morrison, C.4
Guo, B.5
-
105
-
-
76149135992
-
Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation
-
doi: 10.1111/j.1742-4658.2009.07542.x
-
Pan, L., Matloob, A. F., Du, J., Pan, H., Dong, Z., Zhao, J., et al. (2010). Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation. FEBS J. 277, 989-999. doi: 10.1111/j.1742-4658.2009.07542.x
-
(2010)
FEBS J.
, vol.277
, pp. 989-999
-
-
Pan, L.1
Matloob, A.F.2
Du, J.3
Pan, H.4
Dong, Z.5
Zhao, J.6
-
106
-
-
84891071460
-
Histone deacetylases: a saga of perturbed acetylation homeostasis in cancer
-
doi: 10.1369/0022155413506582
-
Parbin, S., Kar, S., Shilpi, A., Sengupta, D., Deb, M., Rath, S. K., et al. (2014). Histone deacetylases: a saga of perturbed acetylation homeostasis in cancer. J. Histochem. Cytochem. 62, 11-33. doi: 10.1369/0022155413506582
-
(2014)
J. Histochem. Cytochem.
, vol.62
, pp. 11-33
-
-
Parbin, S.1
Kar, S.2
Shilpi, A.3
Sengupta, D.4
Deb, M.5
Rath, S.K.6
-
108
-
-
78049286684
-
Histone demethylases in development and disease
-
doi: 10.1016/j.tcb.2010.08.011
-
Pedersen, M. T., and Helin, K. (2010). Histone demethylases in development and disease. Trends Cell Biol. 20, 662-671. doi: 10.1016/j.tcb.2010.08.011
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 662-671
-
-
Pedersen, M.T.1
Helin, K.2
-
109
-
-
55749104413
-
Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes
-
Pendas-Franco, N., Aguilera, O., Pereira, F., Gonzalez-Sancho, J. M., and Munoz, A. (2008). Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes. Anticancer Res. 28, 2613-2623.
-
(2008)
Anticancer Res.
, vol.28
, pp. 2613-2623
-
-
Pendas-Franco, N.1
Aguilera, O.2
Pereira, F.3
Gonzalez-Sancho, J.M.4
Munoz, A.5
-
110
-
-
81255147963
-
KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells
-
doi: 10.1093/hmg/ddr399
-
Pereira, F., Barbachano, A., Silva, J., Bonilla, F., Campbell, M. J., Munoz, A., et al. (2011). KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells. Hum. Mol. Genet. 20, 4655-4665. doi: 10.1093/hmg/ddr399
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 4655-4665
-
-
Pereira, F.1
Barbachano, A.2
Silva, J.3
Bonilla, F.4
Campbell, M.J.5
Munoz, A.6
-
111
-
-
84858734484
-
Vitamin D has wide regulatory effects on histone demethylase genes
-
doi: 10.4161/cc.11.6.19508
-
Pereira, F., Barbachano, A., Singh, P. K., Campbell, M. J., Munoz, A., and Larriba, M. J. (2012). Vitamin D has wide regulatory effects on histone demethylase genes. Cell Cycle 11, 1081-1089. doi: 10.4161/cc.11.6.19508
-
(2012)
Cell Cycle
, vol.11
, pp. 1081-1089
-
-
Pereira, F.1
Barbachano, A.2
Singh, P.K.3
Campbell, M.J.4
Munoz, A.5
Larriba, M.J.6
-
112
-
-
38149045693
-
DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression
-
doi: 10.1126/science.1147674
-
Perillo, B., Ombra, M. N., Bertoni, A., Cuozzo, C., Sacchetti, S., Sasso, A., et al. (2008). DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression. Science 319, 202-206. doi: 10.1126/science.1147674
-
(2008)
Science
, vol.319
, pp. 202-206
-
-
Perillo, B.1
Ombra, M.N.2
Bertoni, A.3
Cuozzo, C.4
Sacchetti, S.5
Sasso, A.6
-
113
-
-
41149116609
-
Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process
-
doi: 10.1073/pnas.0711865105
-
Pfau, R., Tzatsos, A., Kampranis, S. C., Serebrennikova, O. B., Bear, S. E., and Tsichlis, P. N. (2008). Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process. Proc. Natl. Acad. Sci. U.SA. 105, 1907-1912. doi: 10.1073/pnas.0711865105
-
(2008)
Proc. Natl. Acad. Sci. U.SA.
, vol.105
, pp. 1907-1912
-
-
Pfau, R.1
Tzatsos, A.2
Kampranis, S.C.3
Serebrennikova, O.B.4
Bear, S.E.5
Tsichlis, P.N.6
-
114
-
-
84906790954
-
Fundamentals of vitamin D hormone-regulated gene expression
-
doi: 10.1016/j.jsbmb.2013.11.004. [Epub ahead of print].
-
Pike, J. W., and Meyer, M. B. (2013). Fundamentals of vitamin D hormone-regulated gene expression. J. Steroid Biochem. Mol. Biol. doi: 10.1016/j.jsbmb.2013.11.004. [Epub ahead of print].
-
(2013)
J. Steroid Biochem. Mol. Biol
-
-
Pike, J.W.1
Meyer, M.B.2
-
115
-
-
84858154398
-
Regulation of target gene expression by the vitamin D receptor - an update on mechanisms
-
doi: 10.1007/s11154-011-9198-9
-
Pike, J. W., Meyer, M. B., and Bishop, K. A. (2012). Regulation of target gene expression by the vitamin D receptor - an update on mechanisms. Rev. Endocr. Metab. Disord. 13, 45-55. doi: 10.1007/s11154-011-9198-9
-
(2012)
Rev. Endocr. Metab. Disord.
, vol.13
, pp. 45-55
-
-
Pike, J.W.1
Meyer, M.B.2
Bishop, K.A.3
-
116
-
-
0033918407
-
VDR-Alien: a novel, DNA-selective vitamin D(3) receptor-corepressor partnership
-
doi: 10.1096/fj.14.10.1455
-
Polly, P., Herdick, M., Moehren, U., Baniahmad, A., Heinzel, T., and Carlberg, C. (2000). VDR-Alien: a novel, DNA-selective vitamin D(3) receptor-corepressor partnership. FASEB J. 14, 1455-1463. doi: 10.1096/fj.14.10.1455
-
(2000)
FASEB J.
, vol.14
, pp. 1455-1463
-
-
Polly, P.1
Herdick, M.2
Moehren, U.3
Baniahmad, A.4
Heinzel, T.5
Carlberg, C.6
-
117
-
-
0035810045
-
Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A
-
doi: 10.1038/sj.onc.1204269
-
Rashid, S. F., Moore, J. S., Walker, E., Driver, P. M., Engel, J., Edwards, C. E., et al. (2001). Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. Oncogene 20, 1860-1872. doi: 10.1038/sj.onc.1204269
-
(2001)
Oncogene
, vol.20
, pp. 1860-1872
-
-
Rashid, S.F.1
Moore, J.S.2
Walker, E.3
Driver, P.M.4
Engel, J.5
Edwards, C.E.6
-
118
-
-
84867785696
-
Vitamin D intake is negatively associated with promoter methylation of the Wnt antagonist gene DKK1 in a large group of colorectal cancer patients
-
doi: 10.1080/01635581.2012.711418
-
Rawson, J. B., Sun, Z., Dicks, E., Daftary, D., Parfrey, P. S., Green, R. C., et al. (2012). Vitamin D intake is negatively associated with promoter methylation of the Wnt antagonist gene DKK1 in a large group of colorectal cancer patients. Nutr. Cancer 64, 919-928. doi: 10.1080/01635581.2012.711418
-
(2012)
Nutr. Cancer
, vol.64
, pp. 919-928
-
-
Rawson, J.B.1
Sun, Z.2
Dicks, E.3
Daftary, D.4
Parfrey, P.S.5
Green, R.C.6
-
119
-
-
17744391429
-
Co-evolution of X-chromosome inactivation and imprinting in mammals
-
doi: 10.1038/nrg1602
-
Reik, W., and Lewis, A. (2005). Co-evolution of X-chromosome inactivation and imprinting in mammals. Nat. Rev. Genet. 6, 403-410. doi: 10.1038/nrg1602
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 403-410
-
-
Reik, W.1
Lewis, A.2
-
120
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
doi: 10.1038/416552a
-
Rhee, I., Bachman, K. E., Park, B. H., Jair, K. W., Yen, R. W., Schuebel, K. E., et al. (2002). DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 416, 552-556. doi: 10.1038/416552a
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.W.4
Yen, R.W.5
Schuebel, K.E.6
-
121
-
-
0034720284
-
CpG methylation is maintained in human cancer cells lacking DNMT1
-
doi: 10.1038/35010000
-
Rhee, I., Jair, K. W., Yen, R. W., Lengauer, C., Herman, J. G., Kinzler, K. W., et al. (2000). CpG methylation is maintained in human cancer cells lacking DNMT1. Nature 404, 1003-1007. doi: 10.1038/35010000
-
(2000)
Nature
, vol.404
, pp. 1003-1007
-
-
Rhee, I.1
Jair, K.W.2
Yen, R.W.3
Lengauer, C.4
Herman, J.G.5
Kinzler, K.W.6
-
122
-
-
22844457491
-
DNA methylation and human disease
-
doi: 10.1038/nrg1655
-
Robertson, K. D. (2005). DNA methylation and human disease. Nat. Rev. Genet. 6, 597-610. doi: 10.1038/nrg1655
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 597-610
-
-
Robertson, K.D.1
-
123
-
-
33744805399
-
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
-
doi: 10.1016/j.ccr.2006.04.020
-
Saito, Y., Liang, G., Egger, G., Friedman, J. M., Chuang, J. C., Coetzee, G. A., et al. (2006). Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9, 435-443. doi: 10.1016/j.ccr.2006.04.020
-
(2006)
Cancer Cell
, vol.9
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
Friedman, J.M.4
Chuang, J.C.5
Coetzee, G.A.6
-
124
-
-
0025891856
-
Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene
-
Sakai, T., Toguchida, J., Ohtani, N., Yandell, D. W., Rapaport, J. M., and Dryja, T. P. (1991). Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene. Am. J. Hum. Genet. 48, 880-888.
-
(1991)
Am. J. Hum. Genet.
, vol.48
, pp. 880-888
-
-
Sakai, T.1
Toguchida, J.2
Ohtani, N.3
Yandell, D.W.4
Rapaport, J.M.5
Dryja, T.P.6
-
127
-
-
62449197931
-
Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy
-
doi: 10.1158/0008-5472.CAN-08-1735
-
Schulte, J. H., Lim, S., Schramm, A., Friedrichs, N., Koster, J., Versteeg, R., et al. (2009). Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy. Cancer Res. 69, 2065-2071. doi: 10.1158/0008-5472.CAN-08-1735
-
(2009)
Cancer Res.
, vol.69
, pp. 2065-2071
-
-
Schulte, J.H.1
Lim, S.2
Schramm, A.3
Friedrichs, N.4
Koster, J.5
Versteeg, R.6
-
128
-
-
38649123072
-
Conserved metabolic regulatory functions of sirtuins
-
doi: 10.1016/j.cmet.2007.11.006
-
Schwer, B., and Verdin, E. (2008). Conserved metabolic regulatory functions of sirtuins. Cell Metab. 7, 104-112. doi: 10.1016/j.cmet.2007.11.006
-
(2008)
Cell Metab.
, vol.7
, pp. 104-112
-
-
Schwer, B.1
Verdin, E.2
-
129
-
-
84887574192
-
3-dependent chromatin accessibility of early vitamin D receptor target genes
-
doi: 10.1016/j.bbagrm.2013.10.003
-
3-dependent chromatin accessibility of early vitamin D receptor target genes. Biochim. Biophys. Acta 1829, 1266-1275. doi: 10.1016/j.bbagrm.2013.10.003
-
(2013)
Biochim. Biophys. Acta
, vol.1829
, pp. 1266-1275
-
-
Seuter, S.1
Pehkonen, P.2
Heikkinen, S.3
Carlberg, C.4
-
130
-
-
33845611987
-
Discovery of novel epigenetic markers in non-Hodgkin's lymphoma
-
doi: 10.1093/carcin/bgl092
-
Shi, H., Guo, J., Duff, D. J., Rahmatpanah, F., Chitima-Matsiga, R., Al-Kuhlani, M., et al. (2007). Discovery of novel epigenetic markers in non-Hodgkin's lymphoma. Carcinogenesis 28, 60-70. doi: 10.1093/carcin/bgl092
-
(2007)
Carcinogenesis
, vol.28
, pp. 60-70
-
-
Shi, H.1
Guo, J.2
Duff, D.J.3
Rahmatpanah, F.4
Chitima-Matsiga, R.5
Al-Kuhlani, M.6
-
131
-
-
0036605995
-
Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells
-
Shi, H., Yan, P. S., Chen, C. M., Rahmatpanah, F., Lofton-Day, C., Caldwell, C. W., et al. (2002). Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells. Cancer Res. 62, 3214-3220.
-
(2002)
Cancer Res.
, vol.62
, pp. 3214-3220
-
-
Shi, H.1
Yan, P.S.2
Chen, C.M.3
Rahmatpanah, F.4
Lofton-Day, C.5
Caldwell, C.W.6
-
132
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
doi: 10.1016/j.cell.2004.12.012
-
Shi, Y., Lan, F., Matson, C., Mulligan, P., Whetstine, J. R., Cole, P. A., et al. (2004). Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119, 941-953. doi: 10.1016/j.cell.2004.12.012
-
(2004)
Cell
, vol.119
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
Cole, P.A.6
-
133
-
-
33846025127
-
Dynamic regulation of histone lysine methylation by demethylases
-
doi: 10.1016/j.molcel.2006.12.010
-
Shi, Y., and Whetstine, J. R. (2007). Dynamic regulation of histone lysine methylation by demethylases. Mol. Cell 25, 1-14. doi: 10.1016/j.molcel.2006.12.010
-
(2007)
Mol. Cell
, vol.25
, pp. 1-14
-
-
Shi, Y.1
Whetstine, J.R.2
-
134
-
-
84881184830
-
Epigenetic distortion to VDR transcriptional regulation in prostate cancer cells
-
doi: 10.1016/j.jsbmb.2012.10.002
-
Singh, P. K., Doig, C. L., Dhiman, V. K., Turner, B. M., Smiraglia, D. J., and Campbell, M. J. (2013). Epigenetic distortion to VDR transcriptional regulation in prostate cancer cells. J. Steroid Biochem. Mol. Biol. 136, 258-263. doi: 10.1016/j.jsbmb.2012.10.002
-
(2013)
J. Steroid Biochem. Mol. Biol.
, vol.136
, pp. 258-263
-
-
Singh, P.K.1
Doig, C.L.2
Dhiman, V.K.3
Turner, B.M.4
Smiraglia, D.J.5
Campbell, M.J.6
-
135
-
-
84891676806
-
Global and gene-specific promoter methylation analysis in primary hyperparathyroidism
-
doi: 10.4161/epi.24823
-
Sulaiman, L., Juhlin, C. C., Nilsson, I. L., Fotouhi, O., Larsson, C., and Hashemi, J. (2013). Global and gene-specific promoter methylation analysis in primary hyperparathyroidism. Epigenetics 8, 646-655. doi: 10.4161/epi.24823
-
(2013)
Epigenetics
, vol.8
, pp. 646-655
-
-
Sulaiman, L.1
Juhlin, C.C.2
Nilsson, I.L.3
Fotouhi, O.4
Larsson, C.5
Hashemi, J.6
-
136
-
-
34249900454
-
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation
-
doi: 10.1038/nature05823
-
Tahiliani, M., Mei, P., Fang, R., Leonor, T., Rutenberg, M., Shimizu, F., et al. (2007). The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature 447, 601-605. doi: 10.1038/nature05823
-
(2007)
Nature
, vol.447
, pp. 601-605
-
-
Tahiliani, M.1
Mei, P.2
Fang, R.3
Leonor, T.4
Rutenberg, M.5
Shimizu, F.6
-
138
-
-
69449102520
-
Genome-wide analysis of histone H3 lysine9 modifications in human mesenchymal stem cell osteogenic differentiation
-
doi: 10.1371/journal.pone.0006792
-
Tan, J., Lu, J., Huang, W., Dong, Z., Kong, C., Li, L., et al. (2009). Genome-wide analysis of histone H3 lysine9 modifications in human mesenchymal stem cell osteogenic differentiation. PLoS ONE 4:e6792. doi: 10.1371/journal.pone.0006792
-
(2009)
PLoS ONE
, vol.4
-
-
Tan, J.1
Lu, J.2
Huang, W.3
Dong, Z.4
Kong, C.5
Li, L.6
-
139
-
-
84872607594
-
Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa
-
doi: 10.1111/acel.12030
-
Tapp, H. S., Commane, D. M., Bradburn, D. M., Arasaradnam, R., Mathers, J. C., Johnson, I. T., et al. (2013). Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa. Aging Cell 12, 148-155. doi: 10.1111/acel.12030
-
(2013)
Aging Cell
, vol.12
, pp. 148-155
-
-
Tapp, H.S.1
Commane, D.M.2
Bradburn, D.M.3
Arasaradnam, R.4
Mathers, J.C.5
Johnson, I.T.6
-
140
-
-
33845417885
-
The cancer epigenome-components and functional correlates
-
doi: 10.1101/gad.1464906
-
Ting, A. H., McGarvey, K. M., and Baylin, S. B. (2006). The cancer epigenome-components and functional correlates. Genes Dev. 20, 3215-3231. doi: 10.1101/gad.1464906
-
(2006)
Genes Dev.
, vol.20
, pp. 3215-3231
-
-
Ting, A.H.1
McGarvey, K.M.2
Baylin, S.B.3
-
141
-
-
79952532412
-
Cancer epigenetics: linking basic biology to clinical medicine
-
doi: 10.1038/cr.2011.24
-
Tsai, H. C., and Baylin, S. B. (2011). Cancer epigenetics: linking basic biology to clinical medicine. Cell Res. 21, 502-517. doi: 10.1038/cr.2011.24
-
(2011)
Cell Res.
, vol.21
, pp. 502-517
-
-
Tsai, H.C.1
Baylin, S.B.2
-
142
-
-
32844454603
-
Histone demethylation by a family of JmjC domain-containing proteins
-
doi: 10.1038/nature04433
-
Tsukada, Y., Fang, J., Erdjument-Bromage, H., Warren, M. E., Borchers, C. H., Tempst, P., et al. (2006). Histone demethylation by a family of JmjC domain-containing proteins. Nature 439, 811-816. doi: 10.1038/nature04433
-
(2006)
Nature
, vol.439
, pp. 811-816
-
-
Tsukada, Y.1
Fang, J.2
Erdjument-Bromage, H.3
Warren, M.E.4
Borchers, C.H.5
Tempst, P.6
-
143
-
-
84899411750
-
PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion, and anti-migration and -invasion activity of vitamin D
-
doi: 10.1038/onc.2013.123
-
Vanoirbeek, E., Eelen, G., Verlinden, L., Carmeliet, G., Mathieu, C., Bouillon, R., et al. (2014). PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion, and anti-migration and -invasion activity of vitamin D. Oncogene 33, 1904-1911. doi: 10.1038/onc.2013.123
-
(2014)
Oncogene
, vol.33
, pp. 1904-1911
-
-
Vanoirbeek, E.1
Eelen, G.2
Verlinden, L.3
Carmeliet, G.4
Mathieu, C.5
Bouillon, R.6
-
144
-
-
84885212131
-
Methylation status of the CpG islands in vitamin D and calcium-sensing receptor gene promoters does not explain the reduced gene expressions in parathyroid adenomas
-
doi: 10.1210/jc.2013-1699
-
Varshney, S., Bhadada, S. K., Sachdeva, N., Arya, A. K., Saikia, U. N., Behera, A., et al. (2013). Methylation status of the CpG islands in vitamin D and calcium-sensing receptor gene promoters does not explain the reduced gene expressions in parathyroid adenomas. J. Clin. Endocrinol. Metab. 98, E1631-E1635. doi: 10.1210/jc.2013-1699
-
(2013)
J. Clin. Endocrinol. Metab.
, vol.98
-
-
Varshney, S.1
Bhadada, S.K.2
Sachdeva, N.3
Arya, A.K.4
Saikia, U.N.5
Behera, A.6
-
145
-
-
77949873898
-
Vitamin D controls T cell antigen receptor signaling and activation of human T cells
-
doi: 10.1038/ni.1851
-
Von Essen, M. R., Kongsbak, M., Schjerling, P., Olgaard, K., Odum, N., and Geisler, C. (2010). Vitamin D controls T cell antigen receptor signaling and activation of human T cells. Nat. Immunol. 11, 344-349. doi: 10.1038/ni.1851
-
(2010)
Nat. Immunol.
, vol.11
, pp. 344-349
-
-
Von Essen, M.R.1
Kongsbak, M.2
Schjerling, P.3
Olgaard, K.4
Odum, N.5
Geisler, C.6
-
146
-
-
2442684104
-
An evaluation of new criteria for CpG islands in the human genome as gene markers
-
doi: 10.1093/bioinformatics/bth059
-
Wang, Y., and Leung, F. C. (2004). An evaluation of new criteria for CpG islands in the human genome as gene markers. Bioinformatics 20, 1170-1177. doi: 10.1093/bioinformatics/bth059
-
(2004)
Bioinformatics
, vol.20
, pp. 1170-1177
-
-
Wang, Y.1
Leung, F.C.2
-
147
-
-
33646124469
-
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases
-
doi: 10.1016/j.cell.2006.03.028
-
Whetstine, J. R., Nottke, A., Lan, F., Huarte, M., Smolikov, S., Chen, Z., et al. (2006). Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. Cell 125, 467-481. doi: 10.1016/j.cell.2006.03.028
-
(2006)
Cell
, vol.125
, pp. 467-481
-
-
Whetstine, J.R.1
Nottke, A.2
Lan, F.3
Huarte, M.4
Smolikov, S.5
Chen, Z.6
-
148
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
doi: 10.1038/nature10066
-
Williams, K., Christensen, J., Pedersen, M. T., Johansen, J. V., Cloos, P. A., Rappsilber, J., et al. (2011). TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473, 343-348. doi: 10.1038/nature10066
-
(2011)
Nature
, vol.473
, pp. 343-348
-
-
Williams, K.1
Christensen, J.2
Pedersen, M.T.3
Johansen, J.V.4
Cloos, P.A.5
Rappsilber, J.6
-
149
-
-
33744956666
-
Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer
-
doi: 10.1074/jbc.M510023200
-
Wilson, A. J., Byun, D. S., Popova, N., Murray, L. B., L'Italien, K., Sowa, Y., et al. (2006). Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer. J. Biol. Chem. 281, 13548-13558. doi: 10.1074/jbc.M510023200
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 13548-13558
-
-
Wilson, A.J.1
Byun, D.S.2
Popova, N.3
Murray, L.B.4
L'Italien, K.5
Sowa, Y.6
-
150
-
-
77954756915
-
Epigenetic regulation of vitamin D converting enzymes
-
doi: 10.1016/j.jsbmb.2010.03.056
-
Wjst, M., Heimbeck, I., Kutschke, D., and Pukelsheim, K. (2010). Epigenetic regulation of vitamin D converting enzymes. J. Steroid Biochem. Mol. Biol. 121, 80-83. doi: 10.1016/j.jsbmb.2010.03.056
-
(2010)
J. Steroid Biochem. Mol. Biol.
, vol.121
, pp. 80-83
-
-
Wjst, M.1
Heimbeck, I.2
Kutschke, D.3
Pukelsheim, K.4
-
151
-
-
37649023563
-
JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer
-
doi: 10.1073/pnas.0700735104
-
Xiang, Y., Zhu, Z., Han, G., Ye, X., Xu, B., Peng, Z., et al. (2007). JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer. Proc. Natl. Acad. Sci. U.S.A. 104, 19226-19231. doi: 10.1073/pnas.0700735104
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 19226-19231
-
-
Xiang, Y.1
Zhu, Z.2
Han, G.3
Ye, X.4
Xu, B.5
Peng, Z.6
-
152
-
-
84871438065
-
Tet1 controls meiosis by regulating meiotic gene expression
-
doi: 10.1038/nature11709
-
Yamaguchi, S., Hong, K., Liu, R., Shen, L., Inoue, A., Diep, D., et al. (2012). Tet1 controls meiosis by regulating meiotic gene expression. Nature 492, 443-447. doi: 10.1038/nature11709
-
(2012)
Nature
, vol.492
, pp. 443-447
-
-
Yamaguchi, S.1
Hong, K.2
Liu, R.3
Shen, L.4
Inoue, A.5
Diep, D.6
-
153
-
-
33947244845
-
PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation
-
doi: 10.1016/j.molcel.2007.03.001
-
Yamane, K., Tateishi, K., Klose, R. J., Fang, J., Fabrizio, L. A., Erdjument-Bromage, H., et al. (2007). PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. Mol. Cell 25, 801-812. doi: 10.1016/j.molcel.2007.03.001
-
(2007)
Mol. Cell
, vol.25
, pp. 801-812
-
-
Yamane, K.1
Tateishi, K.2
Klose, R.J.3
Fang, J.4
Fabrizio, L.A.5
Erdjument-Bromage, H.6
-
154
-
-
70449707918
-
Vitamin D for treatment and prevention of infectious diseases: a systematic review of randomized controlled trials
-
doi: 10.4158/EP09101.ORR
-
Yamshchikov, A. V., Desai, N. S., Blumberg, H. M., Ziegler, T. R., and Tangpricha, V. (2009). Vitamin D for treatment and prevention of infectious diseases: a systematic review of randomized controlled trials. Endocr. Pract. 15, 438-449. doi: 10.4158/EP09101.ORR
-
(2009)
Endocr. Pract.
, vol.15
, pp. 438-449
-
-
Yamshchikov, A.V.1
Desai, N.S.2
Blumberg, H.M.3
Ziegler, T.R.4
Tangpricha, V.5
-
155
-
-
0021238931
-
3 (1,25(OH)2D3) on neoplastic and osteoblastic phenotype in clonal rat osteosarcoma cells
-
doi: 10.1016/0006-291X(84)90748-4
-
3 (1,25(OH)2D3) on neoplastic and osteoblastic phenotype in clonal rat osteosarcoma cells. Biochem. Biophys. Res. Commun. 121, 796-801. doi: 10.1016/0006-291X(84)90748-4
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.121
, pp. 796-801
-
-
Yoneda, T.1
Aya, S.2
Sakuda, M.3
-
156
-
-
33646805365
-
Vitamin D receptor is a novel drug target for ovarian cancer treatment
-
doi: 10.2174/156800906776842939
-
Zhang, X., Nicosia, S. V., and Bai, W. (2006). Vitamin D receptor is a novel drug target for ovarian cancer treatment. Curr. Cancer Drug. Targets 6, 229-244. doi: 10.2174/156800906776842939
-
(2006)
Curr. Cancer Drug. Targets
, vol.6
, pp. 229-244
-
-
Zhang, X.1
Nicosia, S.V.2
Bai, W.3
-
157
-
-
26244441525
-
Quantitation of HDAC1 mRNA expression in invasive carcinoma of the breast*
-
doi: 10.1007/s10549-005-6001-1
-
Zhang, Z., Yamashita, H., Toyama, T., Sugiura, H., Ando, Y., Mita, K., et al. (2005). Quantitation of HDAC1 mRNA expression in invasive carcinoma of the breast*. Breast Cancer Res. Treat. 94, 11-16. doi: 10.1007/s10549-005-6001-1
-
(2005)
Breast Cancer Res. Treat.
, vol.94
, pp. 11-16
-
-
Zhang, Z.1
Yamashita, H.2
Toyama, T.3
Sugiura, H.4
Ando, Y.5
Mita, K.6
-
158
-
-
84876681149
-
A genome-wide methylation study of severe vitamin D deficiency in African American adolescents
-
doi: 10.1016/j.jpeds.2012.10.059
-
Zhu, H., Wang, X., Shi, H., Su, S., Harshfield, G. A., Gutin, B., et al. (2013). A genome-wide methylation study of severe vitamin D deficiency in African American adolescents. J. Pediatr. 162, 1004-1009.e1001. doi: 10.1016/j.jpeds.2012.10.059
-
(2013)
J. Pediatr.
, vol.162
-
-
Zhu, H.1
Wang, X.2
Shi, H.3
Su, S.4
Harshfield, G.A.5
Gutin, B.6
-
159
-
-
2342603414
-
Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis
-
doi: 10.1016/S1535-6108(04)00114-X
-
Zhu, P., Martin, E., Mengwasser, J., Schlag, P., Janssen, K. P., and Göttlicher, M. (2004). Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis. Cancer Cell 5, 455-463. doi: 10.1016/S1535-6108(04)00114-X
-
(2004)
Cancer Cell
, vol.5
, pp. 455-463
-
-
Zhu, P.1
Martin, E.2
Mengwasser, J.3
Schlag, P.4
Janssen, K.P.5
Göttlicher, M.6
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