Histone deacetylase inhibitor trichostatin a promotes the osteogenic differentiation of rat adipose-derived stem cells by altering the epigenetic modifications on Runx2 promoter in a BMP signaling-dependent manner

Stem Cells and Development

Volumn 22, Issue 2, 2013, Pages 248-255

  Hu, Xiaoqing ^a   Zhang, Xin ^a   Dai, Linghui ^a   Zhu, Jingxian ^a   Jia, Zhuqing ^b   Wang, Weiping ^b   Zhou, Chunyan ^b   Ao, Yingfang ^a  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; TRANSCRIPTION FACTOR RUNX2; TRICHOSTATIN A;

ADIPOSE DERIVED STEM CELL; ADULT STEM CELL; ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE REGENERATION; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; DNA MODIFICATION; EPIGENETICS; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION; RAT; SIGNAL TRANSDUCTION;

ADIPOSE TISSUE; ANIMALS; ANTHRAQUINONES; APOPTOSIS; BONE MARROW; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; CORE BINDING FACTOR ALPHA 1 SUBUNIT; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPIGENESIS, GENETIC; HISTONE DEACETYLASE INHIBITORS; HYDROXAMIC ACIDS; OSTEOGENESIS; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STEM CELLS; TIME FACTORS; TRANSCRIPTION, GENETIC;

RATTUS;

EID: 84872481094     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2012.0105     Document Type: Article

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