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Volumn 10, Issue 2, 2014, Pages 72-74

Epigenetics in 2013: DNA methylation and miRNA - Key roles in systemic autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNITY; DNA METHYLATION; EPIGENOMICS; GENE EXPRESSION REGULATION; HUMANS; MICRORNAS; PROTEIN PHOSPHATASE 2;

EID: 84895155334     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2013.211     Document Type: Review
Times cited : (41)

References (10)
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    • Coit, P. et al. Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naive CD4+ T cells from lupus patients. J. Autoimmun. 43, 78-84 (2013).
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  • 2
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    • The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1 protein pathway in Tcells from controls and systemic lupus erythematosus patients
    • Sunahori, K. et al. The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1 protein pathway in Tcells from controls and systemic lupus erythematosus patients. J. Biol. Chem. 288, 21936-21944 (2013).
    • (2013) J. Biol. Chem , vol.288 , pp. 21936-21944
    • Sunahori, K.1
  • 3
    • 84875943253 scopus 로고    scopus 로고
    • Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression
    • de la Rica, L. et al. Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression. J. Autoimmun. 41, 6-16 (2013).
    • (2013) J. Autoimmun , vol.41 , pp. 6-16
    • De La Rica, L.1
  • 4
    • 84895108812 scopus 로고    scopus 로고
    • Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ Tcell populations
    • Absher, D. M. et al. Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ Tcell populations. PLoS Genet. http://dx.doi.org/1371/journal.pgen.1003
    • PLoS Genet
    • Absher, D.M.1
  • 5
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    • Decreased Rasmitogenactivated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients
    • Deng, C. et al. Decreased Rasmitogenactivated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. Arthritis Rheum. 44, 397-407 (2001).
    • (2001) Arthritis Rheum , vol.44 , pp. 397-407
    • Deng, C.1
  • 6
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    • Defective Tcell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients
    • Sawalha, A. H. et al. Defective Tcell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients. Genes Immun. 9, 368-378 (2008).
    • (2008) Genes Immun , vol.9 , pp. 368-378
    • Sawalha, A.H.1
  • 7
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    • Protein kinase Cδ oxidation contributes to ERK inactivation in lupus T cells
    • Gorelik, G. J., Yarlagadda, S. & Richardson, B. C. Protein kinase Cδ oxidation contributes to ERK inactivation in lupus T cells. Arthritis Rheum. 64, 2964-2974 (2012).
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    • Protein phosphatase 2A is a negative regulator of IL2 production in patients with systemic lupus erythematosus
    • Katsiari, C. G., Kyttaris, V. C., Juang, Y. T. & Tsokos, G. C. Protein phosphatase 2A is a negative regulator of IL2 production in patients with systemic lupus erythematosus. J. Clin. Invest. 115, 3193-3204 (2005).
    • (2005) J. Clin. Invest , vol.115 , pp. 3193-3204
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.