Mir-133a in human circulating monocytes: A potential biomarker associated with postmenopausal osteoporosis

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Wang, Yang ^a   Li, Ling ^a   Moore, Benjamin T ^a   Peng, Xian Hao ^a   Fang, Xiang ^b   Lappe, Joan M ^a   Recker, Robert R ^a   Xiao, Peng ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CREIGHTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CHEMOKINE RECEPTOR CXCR3; CXCL11 CHEMOKINE; INTERLEUKIN 1; INTERLEUKIN 6; MICRORNA; MICRORNA 133A; MICRORNA 382; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZINC TRANSPORTER; CATION TRANSPORT PROTEIN; CXCL11 PROTEIN, HUMAN; CXCR3 PROTEIN, HUMAN; MIRN133 MICRORNA, HUMAN; SLC39A1 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ADULT; ARTICLE; BONE DENSITY; CAUCASIAN; CELL ISOLATION; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; HUMAN CELL; MONOCYTE; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; POSTMENOPAUSE OSTEOPOROSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; UPREGULATION; AGED; BINDING SITE; BLOOD; GENETICS; METABOLISM; MIDDLE AGED;

AGED; BINDING SITES; BIOLOGICAL MARKERS; BONE DENSITY; BONE RESORPTION; CATION TRANSPORT PROTEINS; CHEMOKINE CXCL11; FEMALE; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; MICRORNAS; MIDDLE AGED; MONOCYTES; OSTEOCLASTS; OSTEOPOROSIS, POSTMENOPAUSAL; RECEPTORS, CXCR3; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84859595006     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034641     Document Type: Article

References (64)

1. Li Y, Vandenboom TG, Wang Z, Kong D, Ali S, et al. (2010) miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res 70: 1486-1495.
2. Ma L, Teruya-Feldstein J, Weinberg RA, (2007) Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449: 682-688.
3. Balasubramanyam M, Aravind S, Gokulakrishnan K, Prabu P, Sathishkumar C, et al. (2011) Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes. Mol Cell Biochem 351: 197-205.
4. Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, et al. (2004) A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432: 226-230.
5. Thum T, Gross C, Fiedler J, Fischer T, Kissler S, et al. (2008) MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 456: 980-984.
6. Li Z, Hassan MQ, Volinia S, van Wijnen AJ, Stein JL, et al. (2008) A microRNA signature for a BMP2-induced osteoblast lineage commitment program. Proc Natl Acad Sci U S A 105: 13906-13911.
7. Eskildsen T, Taipaleenmaki H, Stenvang J, Abdallah BM, Ditzel N, et al. (2011) MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo. Proc Natl Acad Sci U S A 108: 6139-6144.
8. Zhang J, Tu Q, Bonewald LF, He X, Stein G, et al. (2011) Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1. J Bone Miner Res 26: 1953-1963.
9. Hassan MQ, Gordon JA, Beloti MM, Croce CM, van Wijnen AJ, et al. (2010) A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program. Proc Natl Acad Sci U S A 107: 19879-19884.
10. Kapinas K, Kessler C, Ricks T, Gronowicz G, Delany AM, (2010) miR-29 modulates Wnt signaling in human osteoblasts through a positive feedback loop. J Biol Chem 285: 25221-25231.
11. Huang J, Zhao L, Xing L, Chen D, (2010) MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation. Stem Cells 28: 357-364.
12. Mizuno Y, Yagi K, Tokuzawa Y, Kanesaki-Yatsuka Y, Suda T, et al. (2008) miR-125b inhibits osteoblastic differentiation by down-regulation of cell proliferation. Biochem Biophys Res Commun 368: 267-272.
13. Luzi E, Marini F, Sala SC, Tognarini I, Galli G, et al. (2008) Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factor. J Bone Miner Res 23: 287-295.
14. Inose H, Ochi H, Kimura A, Fujita K, Xu R, et al. (2009) A microRNA regulatory mechanism of osteoblast differentiation. Proc Natl Acad Sci U S A 106: 20794-20799.
15. Kim YJ, Bae SW, Yu SS, Bae YC, Jung JS, (2009) miR-196a regulates proliferation and osteogenic differentiation in mesenchymal stem cells derived from human adipose tissue. J Bone Miner Res 24: 816-825.
16. Li H, Xie H, Liu W, Hu R, Huang B, et al. (2009) A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans. J Clin Invest 119: 3666-3677.
17. Nakasa T, Shibuya H, Nagata Y, Niimoto T, Ochi M, (2011) The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis. Arthritis Rheum 63: 1582-1590.
18. Sugatani T, Hruska KA, (2007) MicroRNA-223 is a key factor in osteoclast differentiation. J Cell Biochem 101: 996-999.
19. Fujikawa Y, Quinn JM, Sabokbar A, McGee JO, Athanasou NA, (1996) The human osteoclast precursor circulates in the monocyte fraction. Endocrinology 137: 4058-4060.
20. Higuchi S, Tabata N, Tajima M, Ito M, Tsurudome M, et al. (1998) Induction of human osteoclast-like cells by treatment of blood monocytes with anti-fusion regulatory protein-1/CD98 monoclonal antibodies. J Bone Miner Res 13: 44-49.
21. Matayoshi A, Brown C, DiPersio JF, Haug J, Abu-Amer Y, et al. (1996) Human blood-mobilized hematopoietic precursors differentiate into osteoclasts in the absence of stromal cells. Proc Natl Acad Sci U S A 93: 10785-10790.
22. Purton LE, Lee MY, Torok-Storb B, (1996) Normal human peripheral blood mononuclear cells mobilized with granulocyte colony-stimulating factor have increased osteoclastogenic potential compared to nonmobilized blood. Blood 87: 1802-1808.
23. Cohen-Solal ME, Graulet AM, Denne MA, Gueris J, Baylink D, et al. (1993) Peripheral monocyte culture supernatants of menopausal women can induce bone resorption: involvement of cytokines. J Clin Endocrinol Metab 77: 1648-1653.
24. Cohen-Solal ME, Boitte F, Bernard-Poenaru O, Denne MA, Graulet AM, et al. (1998) Increased bone resorbing activity of peripheral monocyte culture supernatants in elderly women. J Clin Endocrinol Metab 83: 1687-1690.
25. Pacifici R, (1996) Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis. J Bone Miner Res 11: 1043-1051.
26. Deng FY, Lei SF, Zhang Y, Zhang YL, Zheng YP, et al. (2011) Peripheral blood monocyte-expressed ANXA2 gene is involved in pathogenesis of osteoporosis in humans. Mol Cell Proteomics 10: M111.
27. Chen XD, Xiao P, Lei SF, Liu YZ, Guo YF, et al. (2010) Gene expression profiling in monocytes and SNP association suggest the importance of the STAT1 gene for osteoporosis in both Chinese and Caucasians. J Bone Miner Res 25: 339-355.
28. Liu YZ, Dvornyk V, Lu Y, Shen H, Lappe JM, et al. (2005) A novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes. J Biol Chem 280: 29011-29016.
29. Xiao P, Chen Y, Jiang H, Liu YZ, Pan F, et al. (2008) In vivo genome-wide expression study on human circulating B cells suggests a novel ESR1 and MAPK3 network for postmenopausal osteoporosis. J Bone Miner Res 23: 644-654.
30. Zerbini CA, Latorre MR, Jaime PC, Tanaka T, Pippa MG, (2000) Bone mineral density in Brazilian men 50 years and older. Braz J Med Biol Res 33: 1429-1435.
31. Rajewsky N, (2006) microRNA target predictions in animals. Nat Genet 38 (Suppl): S8-13.
32. He L, Hannon GJ, (2004) MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5: 522-531.
33. Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
34. Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, et al. (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 27: 91-105.
35. Hsu YH, Zillikens MC, Wilson SG, Farber CR, Demissie S, et al. (2010) An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet 6: e1000977.
36. Ralston SH, Galwey N, MacKay I, Albagha OM, Cardon L, et al. (2005) Loci for regulation of bone mineral density in men and women identified by genome wide linkage scan: the FAMOS study. Hum Mol Genet 14: 943-951.
37. Deng FY, Xiao P, Lei SF, Zhang L, Yang F, et al. (2007) Bivariate whole genome linkage analysis for femoral neck geometric parameters and total body lean mass. J Bone Miner Res 22: 808-816.
38. Mitchell BD, Cole SA, Bauer RL, Iturria SJ, Rodriguez EA, et al. (2000) Genes influencing variation in serum osteocalcin concentrations are linked to markers on chromosomes 16q and 20q. J Clin Endocrinol Metab 85: 1362-1366.
39. Deng Z, Chen JF, Wang DZ, (2011) Transgenic overexpression of miR-133a in skeletal muscle. BMC Musculoskelet Disord 12: 115.
40. McCarthy JJ, Esser KA, (2007) MicroRNA-1 and microRNA-133a expression are decreased during skeletal muscle hypertrophy. J Appl Physiol 102: 306-313.
41. Rao PK, Kumar RM, Farkhondeh M, Baskerville S, Lodish HF, (2006) Myogenic factors that regulate expression of muscle-specific microRNAs. Proc Natl Acad Sci U S A 103: 8721-8726.
42. Huang MB, Xu H, Xie SJ, Zhou H, Qu LH, (2011) Insulin-like growth factor-1 receptor is regulated by microRNA-133 during skeletal myogenesis. PLoS One 6: e29173.
43. Chen JF, Mandel EM, Thomson JM, Wu Q, Callis TE, et al. (2006) The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 38: 228-233.
44. Bostjancic E, Zidar N, Stajer D, Glavac D, (2010) MicroRNAs miR-1, miR-133a, miR-133b and miR-208 are dysregulated in human myocardial infarction. Cardiology 115: 163-169.
45. Villar AV, Merino D, Wenner M, Llano M, Cobo M, et al. (2011) Myocardial gene expression of microRNA-133a and myosin heavy and light chains, in conjunction with clinical parameters, predict regression of left ventricular hypertrophy after valve replacement in patients with aortic stenosis. Heart 97: 1132-1137.
46. Torella D, Iaconetti C, Catalucci D, Ellison GM, Leone A, et al. (2011) MicroRNA-133 controls vascular smooth muscle cell phenotypic switch in vitro and vascular remodeling in vivo. Circ Res 109: 880-893.
47. Liu N, Williams AH, Kim Y, McAnally J, Bezprozvannaya S, et al. (2007) An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133. Proc Natl Acad Sci U S A 104: 20844-20849.
48. Zhang Y, Xie RL, Croce CM, Stein JL, Lian JB, et al. (2011) A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2. Proc Natl Acad Sci U S A 108: 9863-9868.
49. Zhou Q, Zhao ZN, Cheng JT, Zhang B, Xu J, et al. (2011) Ibandronate promotes osteogenic differentiation of periodontal ligament stem cells by regulating the expression of microRNAs. Biochem Biophys Res Commun 404: 127-132.
50. Wang X, (2008) miRDB: a microRNA target prediction and functional annotation database with a wiki interface. RNA 14: 1012-1017.
51. Wang X, El Naqa IM, (2008) Prediction of both conserved and nonconserved microRNA targets in animals. Bioinformatics 24: 325-332.
52. Lewis BP, Burge CB, Bartel DP, (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.
53. Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, et al. (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 27: 91-105.
54. Garcia DM, Baek D, Shin C, Bell GW, Grimson A, et al. (2011) Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs. Nat Struct Mol Biol 18: 1139-1146.
55. Friedman RC, Farh KK, Burge CB, Bartel DP, (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19: 92-105.
56. Coelho LF, Magno de Freitas AG, Mennechet FJ, Blangy A, Uze G, (2005) Interferon-alpha and-beta differentially regulate osteoclastogenesis: role of differential induction of chemokine CXCL11 expression. Proc Natl Acad Sci U S A 102: 11917-11922.
57. Grassi F, Piacentini A, Cristino S, Toneguzzi S, Cavallo C, et al. (2003) Human osteoclasts express different CXC chemokines depending on cell culture substrate: molecular and immunocytochemical evidence of high levels of CXCL10 and CXCL12. Histochem Cell Biol 120: 391-400.
58. Eberle J, Schmidmayer S, Erben RG, Stangassinger M, Roth HP, (1999) Skeletal effects of zinc deficiency in growing rats. J Trace Elem Med Biol 13: 21-26.
59. Nishi Y, (1996) Zinc and growth. J Am Coll Nutr 15: 340-344.
60. Khadeer MA, Sahu SN, Bai G, Abdulla S, Gupta A, (2005) Expression of the zinc transporter ZIP1 in osteoclasts. Bone 37: 296-304.
61. Liu YJ, Shen H, Xiao P, Xiong DH, Li LH, et al. (2006) Molecular genetic studies of gene identification for osteoporosis: a 2004 update. J Bone Miner Res 21: 1511-1535.
62. Chen XD, Xiao P, Lei SF, Liu YZ, Guo YF, et al. (2010) Gene expression profiling in monocytes and SNP association suggest the importance of the STAT1 gene for osteoporosis in both Chinese and Caucasians. J Bone Miner Res 25: 339-355.
63. Atzmon G, Yang XM, Muzumdar R, Ma XH, Gabriely I, et al. (2002) Differential gene expression between visceral and subcutaneous fat depots. Horm Metab Res 34: 622-628.
64. Linder K, Arner P, Flores-Morales A, Tollet-Egnell P, Norstedt G, (2004) Differentially expressed genes in visceral or subcutaneous adipose tissue of obese men and women. J Lipid Res 45: 148-154.