메뉴 건너뛰기




Volumn 8, Issue 1, 2013, Pages

Epigenetic Regulation during Fetal Femur Development: DNA Methylation Matters

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; COLLAGENASE 3; DNA METHYLTRANSFERASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; OSTEOCALCIN; PROTEIN STRO 1; UNCLASSIFIED DRUG;

EID: 84873818150     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054957     Document Type: Article
Times cited : (18)

References (62)
  • 1
    • 0035234557 scopus 로고    scopus 로고
    • Genomic imprinting: parental influence on the genome
    • Reik W, Walter J, (2001) Genomic imprinting: parental influence on the genome. Nat Rev Genet 2: 21-32.
    • (2001) Nat Rev Genet , vol.2 , pp. 21-32
    • Reik, W.1    Walter, J.2
  • 2
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • Robertson KD, (2005) DNA methylation and human disease. Nat Rev Genet 6: 597-610.
    • (2005) Nat Rev Genet , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 3
    • 0035839126 scopus 로고    scopus 로고
    • Epigenetic reprogramming in mammalian development
    • Reik W, Dean W, Walter J, (2001) Epigenetic reprogramming in mammalian development. Science 293: 1089-1093.
    • (2001) Science , vol.293 , pp. 1089-1093
    • Reik, W.1    Dean, W.2    Walter, J.3
  • 4
    • 0029163078 scopus 로고
    • Structure and function of DNA methyltransferases
    • Cheng X, (1995) Structure and function of DNA methyltransferases. Annu Rev Biophys Biomol Struct 24: 293-318.
    • (1995) Annu Rev Biophys Biomol Struct , vol.24 , pp. 293-318
    • Cheng, X.1
  • 5
    • 34247508639 scopus 로고    scopus 로고
    • Epigenetic mechanisms and the mismatch concept of the developmental origins of health and disease
    • Godfrey KM, Lillycrop KA, Burdge GC, Gluckman PD, Hanson MA, (2007) Epigenetic mechanisms and the mismatch concept of the developmental origins of health and disease. Pediatr Res 61: 5R-10R.
    • (2007) Pediatr Res , vol.61
    • Godfrey, K.M.1    Lillycrop, K.A.2    Burdge, G.C.3    Gluckman, P.D.4    Hanson, M.A.5
  • 6
    • 15844398992 scopus 로고    scopus 로고
    • The role of early embryonic environment on epigenotype and phenotype
    • Vickaryous N, Whitelaw E, (2005) The role of early embryonic environment on epigenotype and phenotype. Reprod Fertil Dev 17: 335-340.
    • (2005) Reprod Fertil Dev , vol.17 , pp. 335-340
    • Vickaryous, N.1    Whitelaw, E.2
  • 7
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A, (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16: 6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 8
    • 0035158704 scopus 로고    scopus 로고
    • Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
    • Jackson-Grusby L, Beard C, Possemato R, Tudor M, Fambrough D, et al. (2001) Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet 27: 31-39.
    • (2001) Nat Genet , vol.27 , pp. 31-39
    • Jackson-Grusby, L.1    Beard, C.2    Possemato, R.3    Tudor, M.4    Fambrough, D.5
  • 9
    • 0025119812 scopus 로고
    • Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability
    • Pfeifer GP, Steigerwald SD, Hansen RS, Gartler SM, Riggs AD, (1990) Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability. Proc Natl Acad Sci U S A 87: 8252-8256.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 8252-8256
    • Pfeifer, G.P.1    Steigerwald, S.D.2    Hansen, R.S.3    Gartler, S.M.4    Riggs, A.D.5
  • 10
    • 0035093826 scopus 로고    scopus 로고
    • Evolution of imprinting mechanisms: the battle of the sexes begins in the zygote
    • Reik W, Walter J, (2001) Evolution of imprinting mechanisms: the battle of the sexes begins in the zygote. Nat Genet 27: 255-256.
    • (2001) Nat Genet , vol.27 , pp. 255-256
    • Reik, W.1    Walter, J.2
  • 11
    • 33745480223 scopus 로고    scopus 로고
    • Characterization and multipotentiality of human fetal femur-derived cells: implications for skeletal tissue regeneration
    • Mirmalek-Sani SH, Tare RS, Morgan SM, Roach HI, Wilson DI, et al. (2006) Characterization and multipotentiality of human fetal femur-derived cells: implications for skeletal tissue regeneration. Stem Cells 24: 1042-1053.
    • (2006) Stem Cells , vol.24 , pp. 1042-1053
    • Mirmalek-Sani, S.H.1    Tare, R.S.2    Morgan, S.M.3    Roach, H.I.4    Wilson, D.I.5
  • 12
    • 79951580355 scopus 로고    scopus 로고
    • The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes-implications for osteoarthritis
    • Imagawa K, de Andres MC, Hashimoto K, Pitt D, Itoi E, et al. (2011) The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes-implications for osteoarthritis. Biochem Biophys Res Commun 405: 362-367.
    • (2011) Biochem Biophys Res Commun , vol.405 , pp. 362-367
    • Imagawa, K.1    de Andres, M.C.2    Hashimoto, K.3    Pitt, D.4    Itoi, E.5
  • 13
    • 70350561846 scopus 로고    scopus 로고
    • DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes
    • Hashimoto K, Oreffo RO, Gibson MB, Goldring MB, Roach HI, (2009) DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes. Arthritis Rheum 60: 3303-3313.
    • (2009) Arthritis Rheum , vol.60 , pp. 3303-3313
    • Hashimoto, K.1    Oreffo, R.O.2    Gibson, M.B.3    Goldring, M.B.4    Roach, H.I.5
  • 14
    • 26844518429 scopus 로고    scopus 로고
    • Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions
    • Roach HI, Yamada N, Cheung KS, Tilley S, Clarke NM, et al. (2005) Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions. Arthritis Rheum 52: 3110-3124.
    • (2005) Arthritis Rheum , vol.52 , pp. 3110-3124
    • Roach, H.I.1    Yamada, N.2    Cheung, K.S.3    Tilley, S.4    Clarke, N.M.5
  • 15
    • 65249106542 scopus 로고    scopus 로고
    • Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage
    • da Silva MA, Yamada N, Clarke NM, Roach HI, (2009) Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage. J Orthop Res 27: 593-601.
    • (2009) J Orthop Res , vol.27 , pp. 593-601
    • da Silva, M.A.1    Yamada, N.2    Clarke, N.M.3    Roach, H.I.4
  • 16
    • 0141887410 scopus 로고    scopus 로고
    • STRO-1, HOP-26 (CD63), CD49a and SB-10 (CD166) as markers of primitive human marrow stromal cells and their more differentiated progeny: a comparative investigation in vitro
    • Stewart K, Monk P, Walsh S, Jefferiss CM, Letchford J, et al. (2003) STRO-1, HOP-26 (CD63), CD49a and SB-10 (CD166) as markers of primitive human marrow stromal cells and their more differentiated progeny: a comparative investigation in vitro. Cell Tissue Res 313: 281-290.
    • (2003) Cell Tissue Res , vol.313 , pp. 281-290
    • Stewart, K.1    Monk, P.2    Walsh, S.3    Jefferiss, C.M.4    Letchford, J.5
  • 17
    • 0028102611 scopus 로고
    • The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors
    • Gronthos S, Graves SE, Ohta S, Simmons PJ, (1994) The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors. Blood 84: 4164-4173.
    • (1994) Blood , vol.84 , pp. 4164-4173
    • Gronthos, S.1    Graves, S.E.2    Ohta, S.3    Simmons, P.J.4
  • 18
    • 0032809980 scopus 로고    scopus 로고
    • Further characterization of cells expressing STRO-1 in cultures of adult human bone marrow stromal cells
    • Stewart K, Walsh S, Screen J, Jefferiss CM, Chainey J, et al. (1999) Further characterization of cells expressing STRO-1 in cultures of adult human bone marrow stromal cells. J Bone Miner Res 14: 1345-1356.
    • (1999) J Bone Miner Res , vol.14 , pp. 1345-1356
    • Stewart, K.1    Walsh, S.2    Screen, J.3    Jefferiss, C.M.4    Chainey, J.5
  • 19
    • 38449120061 scopus 로고    scopus 로고
    • Improved quantification of DNA methylation using methylation-sensitive restriction enzymes and real-time PCR
    • Hashimoto K, Kokubun S, Itoi E, Roach HI, (2007) Improved quantification of DNA methylation using methylation-sensitive restriction enzymes and real-time PCR. Epigenetics 2: 86-91.
    • (2007) Epigenetics , vol.2 , pp. 86-91
    • Hashimoto, K.1    Kokubun, S.2    Itoi, E.3    Roach, H.I.4
  • 20
    • 0028271899 scopus 로고
    • Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene
    • Chartrain NA, Geller DA, Koty PP, Sitrin NF, Nussler AK, et al. (1994) Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene. J Biol Chem 269: 6765-6772.
    • (1994) J Biol Chem , vol.269 , pp. 6765-6772
    • Chartrain, N.A.1    Geller, D.A.2    Koty, P.P.3    Sitrin, N.F.4    Nussler, A.K.5
  • 22
    • 0037414825 scopus 로고    scopus 로고
    • Regulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9
    • Zhang P, Jimenez SA, Stokes DG, (2003) Regulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9. J Biol Chem 278: 117-123.
    • (2003) J Biol Chem , vol.278 , pp. 117-123
    • Zhang, P.1    Jimenez, S.A.2    Stokes, D.G.3
  • 23
    • 0031002287 scopus 로고    scopus 로고
    • Cloning, sequencing and characterization of the 5′-flanking region of the human collagenase-3 gene
    • Tardif G, Pelletier JP, Dupuis M, Hambor JE, Martel-Pelletier J, (1997) Cloning, sequencing and characterization of the 5′-flanking region of the human collagenase-3 gene. Biochem J 323 (Pt 1): 13-16.
    • (1997) Biochem J , vol.323 , Issue.Pt 1 , pp. 13-16
    • Tardif, G.1    Pelletier, J.P.2    Dupuis, M.3    Hambor, J.E.4    Martel-Pelletier, J.5
  • 24
    • 0023056241 scopus 로고
    • Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene
    • Clark BD, Collins KL, Gandy MS, Webb AC, Auron PE, (1986) Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene. Nucleic Acids Res 14: 7897-7914.
    • (1986) Nucleic Acids Res , vol.14 , pp. 7897-7914
    • Clark, B.D.1    Collins, K.L.2    Gandy, M.S.3    Webb, A.C.4    Auron, P.E.5
  • 25
    • 0242566968 scopus 로고
    • Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3
    • Kerner SA, Scott RA, Pike JW, (1989) Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3. Proc Natl Acad Sci U S A 86: 4455-4459.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 4455-4459
    • Kerner, S.A.1    Scott, R.A.2    Pike, J.W.3
  • 26
    • 34247109637 scopus 로고    scopus 로고
    • Epigenetic gene regulation: linking early developmental environment to adult disease
    • Dolinoy DC, Weidman JR, Jirtle RL, (2007) Epigenetic gene regulation: linking early developmental environment to adult disease. Reprod Toxicol 23: 297-307.
    • (2007) Reprod Toxicol , vol.23 , pp. 297-307
    • Dolinoy, D.C.1    Weidman, J.R.2    Jirtle, R.L.3
  • 27
    • 79961221664 scopus 로고    scopus 로고
    • The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life
    • Szyf M, (2011) The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life. Epigenetics 6: 971-978.
    • (2011) Epigenetics , vol.6 , pp. 971-978
    • Szyf, M.1
  • 31
    • 0032987629 scopus 로고    scopus 로고
    • Nitric oxide in fracture repair. Differential localisation, expression and activity of nitric oxide synthases
    • Corbett SA, Hukkanen M, Batten J, McCarthy ID, Polak JM, et al. (1999) Nitric oxide in fracture repair. Differential localisation, expression and activity of nitric oxide synthases. J Bone Joint Surg Br 81: 531-537.
    • (1999) J Bone Joint Surg Br , vol.81 , pp. 531-537
    • Corbett, S.A.1    Hukkanen, M.2    Batten, J.3    McCarthy, I.D.4    Polak, J.M.5
  • 33
    • 2942722566 scopus 로고    scopus 로고
    • Nitric oxide mediates ultrasound-induced hypoxia-inducible factor-1alpha activation and vascular endothelial growth factor-A expression in human osteoblasts
    • Wang FS, Kuo YR, Wang CJ, Yang KD, Chang PR, et al. (2004) Nitric oxide mediates ultrasound-induced hypoxia-inducible factor-1alpha activation and vascular endothelial growth factor-A expression in human osteoblasts. Bone 35: 114-123.
    • (2004) Bone , vol.35 , pp. 114-123
    • Wang, F.S.1    Kuo, Y.R.2    Wang, C.J.3    Yang, K.D.4    Chang, P.R.5
  • 34
    • 0035107907 scopus 로고    scopus 로고
    • Nitric oxide synthase isoforms during fracture healing
    • Zhu W, Diwan AD, Lin JH, Murrell GA, (2001) Nitric oxide synthase isoforms during fracture healing. J Bone Miner Res 16: 535-540.
    • (2001) J Bone Miner Res , vol.16 , pp. 535-540
    • Zhu, W.1    Diwan, A.D.2    Lin, J.H.3    Murrell, G.A.4
  • 35
    • 0035139484 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity
    • Aguirre J, Buttery L, O'Shaughnessy M, Afzal F, Fernandez de Marticorena I, et al. (2001) Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity. Am J Pathol 158: 247-257.
    • (2001) Am J Pathol , vol.158 , pp. 247-257
    • Aguirre, J.1    Buttery, L.2    O'Shaughnessy, M.3    Afzal, F.4    Fernandez de Marticorena, I.5
  • 36
    • 0035099851 scopus 로고    scopus 로고
    • Defective bone formation and anabolic response to exogenous estrogen in mice with targeted disruption of endothelial nitric oxide synthase
    • Armour KE, Armour KJ, Gallagher ME, Godecke A, Helfrich MH, et al. (2001) Defective bone formation and anabolic response to exogenous estrogen in mice with targeted disruption of endothelial nitric oxide synthase. Endocrinology 142: 760-766.
    • (2001) Endocrinology , vol.142 , pp. 760-766
    • Armour, K.E.1    Armour, K.J.2    Gallagher, M.E.3    Godecke, A.4    Helfrich, M.H.5
  • 37
    • 0028913960 scopus 로고
    • Bone cell function, regulation, and communication: a role for nitric oxide
    • Collin-Osdoby P, Nickols GA, Osdoby P, (1995) Bone cell function, regulation, and communication: a role for nitric oxide. J Cell Biochem 57: 399-408.
    • (1995) J Cell Biochem , vol.57 , pp. 399-408
    • Collin-Osdoby, P.1    Nickols, G.A.2    Osdoby, P.3
  • 38
    • 0031444851 scopus 로고    scopus 로고
    • Effects of nitric oxide synthase inhibitors on bone formation in rats
    • Turner CH, Owan I, Jacob DS, McClintock R, Peacock M, (1997) Effects of nitric oxide synthase inhibitors on bone formation in rats. Bone 21: 487-490.
    • (1997) Bone , vol.21 , pp. 487-490
    • Turner, C.H.1    Owan, I.2    Jacob, D.S.3    McClintock, R.4    Peacock, M.5
  • 40
    • 0037373564 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase mediates bone loss in ovariectomized mice
    • Cuzzocrea S, Mazzon E, Dugo L, Genovese T, Di Paola R, et al. (2003) Inducible nitric oxide synthase mediates bone loss in ovariectomized mice. Endocrinology 144: 1098-1107.
    • (2003) Endocrinology , vol.144 , pp. 1098-1107
    • Cuzzocrea, S.1    Mazzon, E.2    Dugo, L.3    Genovese, T.4    Di Paola, R.5
  • 41
    • 2042514317 scopus 로고    scopus 로고
    • Nitric oxide donor increases osteoprotegerin production and osteoclastogenesis inhibitory activity in bone marrow stromal cells from ovariectomized rats
    • Wang FS, Wang CJ, Chen YJ, Huang YT, Huang HC, et al. (2004) Nitric oxide donor increases osteoprotegerin production and osteoclastogenesis inhibitory activity in bone marrow stromal cells from ovariectomized rats. Endocrinology 145: 2148-2156.
    • (2004) Endocrinology , vol.145 , pp. 2148-2156
    • Wang, F.S.1    Wang, C.J.2    Chen, Y.J.3    Huang, Y.T.4    Huang, H.C.5
  • 42
    • 0032569965 scopus 로고    scopus 로고
    • Methylation in the initiation region of the first exon suppresses collagen pro-alpha2(I) gene transcription
    • Sengupta PK, Smith BD, (1998) Methylation in the initiation region of the first exon suppresses collagen pro-alpha2(I) gene transcription. Biochim Biophys Acta 1443: 75-89.
    • (1998) Biochim Biophys Acta , vol.1443 , pp. 75-89
    • Sengupta, P.K.1    Smith, B.D.2
  • 43
    • 0026454918 scopus 로고
    • Methylation in the preinitiation domain suppresses gene transcription by an indirect mechanism
    • Levine A, Cantoni GL, Razin A, (1992) Methylation in the preinitiation domain suppresses gene transcription by an indirect mechanism. Proc Natl Acad Sci U S A 89: 10119-10123.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 10119-10123
    • Levine, A.1    Cantoni, G.L.2    Razin, A.3
  • 44
    • 34250188803 scopus 로고    scopus 로고
    • Genomic patterns of DNA methylation: targets and function of an epigenetic mark
    • Weber M, Schubeler D, (2007) Genomic patterns of DNA methylation: targets and function of an epigenetic mark. Curr Opin Cell Biol 19: 273-280.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 273-280
    • Weber, M.1    Schubeler, D.2
  • 45
    • 84858713611 scopus 로고    scopus 로고
    • DNA methylation contributes to the regulation of sclerostin expression in human osteocytes
    • Delgado-Calle J, Sanudo C, Bolado A, Fernandez AF, Arozamena J, et al. (2012) DNA methylation contributes to the regulation of sclerostin expression in human osteocytes. J Bone Miner Res 27: 926-937.
    • (2012) J Bone Miner Res , vol.27 , pp. 926-937
    • Delgado-Calle, J.1    Sanudo, C.2    Bolado, A.3    Fernandez, A.F.4    Arozamena, J.5
  • 46
    • 0030610082 scopus 로고    scopus 로고
    • Absence of the alpha1(IX) chain leads to a functional knock-out of the entire collagen IX protein in mice
    • Hagg R, Hedbom E, Mollers U, Aszodi A, Fassler R, et al. (1997) Absence of the alpha1(IX) chain leads to a functional knock-out of the entire collagen IX protein in mice. J Biol Chem 272: 20650-20654.
    • (1997) J Biol Chem , vol.272 , pp. 20650-20654
    • Hagg, R.1    Hedbom, E.2    Mollers, U.3    Aszodi, A.4    Fassler, R.5
  • 48
    • 43049121285 scopus 로고    scopus 로고
    • Collagen IX-deficiency seriously compromises growth cartilage development in mice
    • Dreier R, Opolka A, Grifka J, Bruckner P, Grassel S, (2008) Collagen IX-deficiency seriously compromises growth cartilage development in mice. Matrix Biol 27: 319-329.
    • (2008) Matrix Biol , vol.27 , pp. 319-329
    • Dreier, R.1    Opolka, A.2    Grifka, J.3    Bruckner, P.4    Grassel, S.5
  • 49
    • 18644375130 scopus 로고    scopus 로고
    • Evidence for a role of the genomic region of the gene encoding for the alpha1 chain of type IX collagen (COL9A1) in hip osteoarthritis: A population-based study
    • Alizadeh BZ, Njajou OT, Bijkerk C, Meulenbelt I, Wildt SC, et al. (2005) Evidence for a role of the genomic region of the gene encoding for the alpha1 chain of type IX collagen (COL9A1) in hip osteoarthritis: A population-based study. Arthritis Rheum 52: 1437-1442.
    • (2005) Arthritis Rheum , vol.52 , pp. 1437-1442
    • Alizadeh, B.Z.1    Njajou, O.T.2    Bijkerk, C.3    Meulenbelt, I.4    Wildt, S.C.5
  • 50
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis S, Heintz N, (2009) The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324: 929-930.
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 51
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
    • Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, et al. (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324: 930-935.
    • (2009) Science , vol.324 , pp. 930-935
    • Tahiliani, M.1    Koh, K.P.2    Shen, Y.3    Pastor, W.A.4    Bandukwala, H.5
  • 52
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5 mC to 5 hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, et al. (2010) Role of Tet proteins in 5 mC to 5 hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466: 1129-1133.
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1    D'Alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5
  • 53
    • 33847055935 scopus 로고    scopus 로고
    • Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1
    • Valinluck V, Sowers LC, (2007) Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res 67: 946-950.
    • (2007) Cancer Res , vol.67 , pp. 946-950
    • Valinluck, V.1    Sowers, L.C.2
  • 54
    • 79956323623 scopus 로고    scopus 로고
    • Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
    • Ficz G, Branco MR, Seisenberger S, Santos F, Krueger F, et al. (2011) Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473: 398-402.
    • (2011) Nature , vol.473 , pp. 398-402
    • Ficz, G.1    Branco, M.R.2    Seisenberger, S.3    Santos, F.4    Krueger, F.5
  • 55
    • 0021268975 scopus 로고
    • Serum bone Gla-protein: a specific marker for bone formation in postmenopausal osteoporosis
    • Brown JP, Delmas PD, Malaval L, Edouard C, Chapuy MC, et al. (1984) Serum bone Gla-protein: a specific marker for bone formation in postmenopausal osteoporosis. Lancet 1: 1091-1093.
    • (1984) Lancet , vol.1 , pp. 1091-1093
    • Brown, J.P.1    Delmas, P.D.2    Malaval, L.3    Edouard, C.4    Chapuy, M.C.5
  • 56
    • 78149281847 scopus 로고    scopus 로고
    • The epigenetic mechanism of mechanically induced osteogenic differentiation
    • Arnsdorf EJ, Tummala P, Castillo AB, Zhang F, Jacobs CR, (2010) The epigenetic mechanism of mechanically induced osteogenic differentiation. J Biomech 43: 2881-2886.
    • (2010) J Biomech , vol.43 , pp. 2881-2886
    • Arnsdorf, E.J.1    Tummala, P.2    Castillo, A.B.3    Zhang, F.4    Jacobs, C.R.5
  • 57
    • 0036197327 scopus 로고    scopus 로고
    • Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts
    • Villagra A, Gutierrez J, Paredes R, Sierra J, Puchi M, et al. (2002) Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts. J Cell Biochem 85: 112-122.
    • (2002) J Cell Biochem , vol.85 , pp. 112-122
    • Villagra, A.1    Gutierrez, J.2    Paredes, R.3    Sierra, J.4    Puchi, M.5
  • 58
    • 33845992511 scopus 로고    scopus 로고
    • Methylation status of a single CpG locus 3 bases upstream of TATA-box of receptor activator of nuclear factor-kappaB ligand (RANKL) gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis
    • Kitazawa R, Kitazawa S, (2007) Methylation status of a single CpG locus 3 bases upstream of TATA-box of receptor activator of nuclear factor-kappaB ligand (RANKL) gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis. Mol Endocrinol 21: 148-158.
    • (2007) Mol Endocrinol , vol.21 , pp. 148-158
    • Kitazawa, R.1    Kitazawa, S.2
  • 59
    • 69249116178 scopus 로고    scopus 로고
    • DNA methylation and histone modification regulate silencing of OPG during tumor progression
    • Lu TY, Kao CF, Lin CT, Huang DY, Chiu CY, et al. (2009) DNA methylation and histone modification regulate silencing of OPG during tumor progression. J Cell Biochem 108: 315-325.
    • (2009) J Cell Biochem , vol.108 , pp. 315-325
    • Lu, T.Y.1    Kao, C.F.2    Lin, C.T.3    Huang, D.Y.4    Chiu, C.Y.5
  • 60
    • 78649663944 scopus 로고    scopus 로고
    • Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A
    • El-Serafi AT, Oreffo RO, Roach HI, (2011) Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A. Differentiation. 81: 35-41.
    • (2011) Differentiation , vol.81 , pp. 35-41
    • El-Serafi, A.T.1    Oreffo, R.O.2    Roach, H.I.3
  • 61
    • 80052282411 scopus 로고    scopus 로고
    • Epigenetic regulation of alkaline phosphatase in human cells of the osteoblastic lineage
    • Delgado-Calle J, Sanudo C, Sanchez-Verde L, Garcia-Renedo RJ, Arozamena J, et al. (2011) Epigenetic regulation of alkaline phosphatase in human cells of the osteoblastic lineage. Bone 49: 830-838.
    • (2011) Bone , vol.49 , pp. 830-838
    • Delgado-Calle, J.1    Sanudo, C.2    Sanchez-Verde, L.3    Garcia-Renedo, R.J.4    Arozamena, J.5
  • 62
    • 84857969990 scopus 로고    scopus 로고
    • Animal models of maternal nutrition and altered offspring bone structure-bone development across the lifecourse
    • discussion 332
    • Lanham SA, Bertram C, Cooper C, Oreffo RO (2011) Animal models of maternal nutrition and altered offspring bone structure-bone development across the lifecourse. Eur Cell Mater 22: 321-332; discussion 332.
    • (2011) Eur Cell Mater , vol.22 , pp. 321-332
    • Lanham, S.A.1    Bertram, C.2    Cooper, C.3    Oreffo, R.O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.