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Volumn 107, Issue 46, 2010, Pages 19879-19884

A network connecting Runx2, SATB2, and the miR-23a∼27a∼24-2 cluster regulates the osteoblast differentiation program

Author keywords

Bone formation by miRs; Feed forward feedback miR control SATB2 targeted by cluster miRs; Runx2 regulation of microRNA cluster phenotype attenuation by miRs

Indexed keywords

MICRORNA; MICRORNA 23A; MICRORNA 24; MICRORNA 27A; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SATB2; UNCLASSIFIED DRUG;

EID: 78650548873     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1007698107     Document Type: Article
Times cited : (326)

References (33)
  • 2
    • 58849090069 scopus 로고    scopus 로고
    • Signaling networks that control the lineage commitment and differentiation of bone cells
    • Soltanoff CS, Yang S, Chen W, Li YP (2009) Signaling networks that control the lineage commitment and differentiation of bone cells. Crit Rev Eukaryot Gene Expr 19:1-46.
    • (2009) Crit Rev Eukaryot Gene Expr , vol.19 , pp. 1-46
    • Soltanoff, C.S.1    Yang, S.2    Chen, W.3    Li, Y.P.4
  • 3
    • 77954757722 scopus 로고    scopus 로고
    • Mitotic bookmarking of genes: A novel dimension to epigenetic control
    • Zaidi SK, et al. (2010) Mitotic bookmarking of genes: A novel dimension to epigenetic control. Nat Rev Genet 11:583-589.
    • (2010) Nat Rev Genet , vol.11 , pp. 583-589
    • Zaidi, S.K.1
  • 4
    • 52949114558 scopus 로고    scopus 로고
    • A microRNA signature for a BMP2-induced osteoblast lineage commitment program
    • Li Z, et al. (2008) A microRNA signature for a BMP2-induced osteoblast lineage commitment program. Proc Natl Acad Sci USA 105:13906-13911.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13906-13911
    • Li, Z.1
  • 5
    • 67650169908 scopus 로고    scopus 로고
    • Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation
    • Li Z, et al. (2009) Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation. J Biol Chem 284:15676-15684.
    • (2009) J Biol Chem , vol.284 , pp. 15676-15684
    • Li, Z.1
  • 6
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP (2004) MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 7
    • 72549085095 scopus 로고    scopus 로고
    • Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function
    • Pawlicki JM, Steitz JA (2010) Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function. Trends Cell Biol 20:52-61.
    • (2010) Trends Cell Biol , vol.20 , pp. 52-61
    • Pawlicki, J.M.1    Steitz, J.A.2
  • 9
    • 73349125465 scopus 로고    scopus 로고
    • MicroRNAs in cancer: Small molecules with a huge impact
    • lorio MV, Croce CM (2009) MicroRNAs in cancer: Small molecules with a huge impact. J Clin Oncol 27:5848-5856.
    • (2009) J Clin Oncol , vol.27 , pp. 5848-5856
    • Lorio, M.V.1    Croce, C.M.2
  • 10
    • 75649139134 scopus 로고    scopus 로고
    • Physiological and pathological roles for microRNAs in the immune system
    • O'Connell RM, Rao DS, Chaudhuri AA, Baltimore D (2010) Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol 10:111-122.
    • (2010) Nat Rev Immunol , vol.10 , pp. 111-122
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Baltimore, D.4
  • 11
    • 72849121740 scopus 로고    scopus 로고
    • A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans
    • Li H, et al. (2009) A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans. J Clin Invest 119:3666-3677.
    • (2009) J Clin Invest , vol.119 , pp. 3666-3677
    • Li, H.1
  • 12
    • 77649187445 scopus 로고    scopus 로고
    • Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse
    • Gaur T, et al. (2010) Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse. Dev Biol 340:10-21.
    • (2010) Dev Biol , vol.340 , pp. 10-21
    • Gaur, T.1
  • 13
    • 38549101581 scopus 로고    scopus 로고
    • Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factor
    • Luzi E, et al. (2008) Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factor. J Bone Miner Res 23:287-295.
    • (2008) J Bone Miner Res , vol.23 , pp. 287-295
    • Luzi, E.1
  • 14
    • 67749145694 scopus 로고    scopus 로고
    • MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5.
    • Itoh T, Nozawa Y, Akao Y (2009) MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5. J Biol Chem 284:19272-19279.
    • (2009) J Biol Chem , vol.284 , pp. 19272-19279
    • Itoh, T.1    Nozawa, Y.2    Akao, Y.3
  • 15
    • 77149136767 scopus 로고    scopus 로고
    • MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation
    • Huang J, Zhao L, Xing L, Chen D (2010) MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation. Stem Cells 28:357-364.
    • (2010) Stem Cells , vol.28 , pp. 357-364
    • Huang, J.1    Zhao, L.2    Xing, L.3    Chen, D.4
  • 16
    • 57449119515 scopus 로고    scopus 로고
    • Human multipotent stromal cells from bone marrow and microRNA: Regulation of differentiation and leukemia inhibitory factor expression
    • Oskowitz AZ, et al. (2008) Human multipotent stromal cells from bone marrow and microRNA: regulation of differentiation and leukemia inhibitory factor expression. Proc Natl Acad Sci USA 105:18372-18377.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 18372-18377
    • Oskowitz, A.Z.1
  • 17
    • 57349146677 scopus 로고    scopus 로고
    • MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin
    • Liu T, Tang H, Lang Y, Liu M, Li X (2009) MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin. Cancer Lett 273:233-242.
    • (2009) Cancer Lett , vol.273 , pp. 233-242
    • Liu, T.1    Tang, H.2    Lang, Y.3    Liu, M.4    Li, X.5
  • 18
    • 47049125858 scopus 로고    scopus 로고
    • Upregulation of miR-23a approximately 27a approximately 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells
    • Huang S, et al. (2008) Upregulation of miR-23a approximately 27a approximately 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells. Int J Cancer 123:972-978.
    • (2008) Int J Cancer , vol.123 , pp. 972-978
    • Huang, S.1
  • 19
    • 36349001297 scopus 로고    scopus 로고
    • The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells
    • Mertens-Talcott SU, Chintharlapalli S, Li X, Safe S (2007) The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Res 67:11001-11011.
    • (2007) Cancer Res , vol.67 , pp. 11001-11011
    • Mertens-Talcott, S.U.1    Chintharlapalli, S.2    Li, X.3    Safe, S.4
  • 21
    • 70350521699 scopus 로고    scopus 로고
    • Altered Runxl subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network
    • Zaidi SK, et al. (2009) Altered Runxl subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network. Cancer Res 69:8249-8255.
    • (2009) Cancer Res , vol.69 , pp. 8249-8255
    • Zaidi, S.K.1
  • 22
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee Y, et al. (2004) MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23:4051-4060.
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1
  • 23
    • 34047234690 scopus 로고    scopus 로고
    • Characterization and identification of microRNA core promoters in four model species
    • Zhou X, Ruan J, Wang G, Zhang W (2007) Characterization and identification of microRNA core promoters in four model species. PLOS Comput Biol 3:e37.
    • (2007) PLOS Comput Biol , vol.3
    • Zhou, X.1    Ruan, J.2    Wang, G.3    Zhang, W.4
  • 24
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • Komori T, et al. (1997) Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89:755-764.
    • (1997) Cell , vol.89 , pp. 755-764
    • Komori, T.1
  • 25
    • 33744536200 scopus 로고    scopus 로고
    • SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation
    • Dobreva G, et al. (2006) SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell 125:971-986.
    • (2006) Cell , vol.125 , pp. 971-986
    • Dobreva, G.1
  • 26
    • 34447253042 scopus 로고    scopus 로고
    • Heterozygous nonsense mutation SATB2 associated with cleft palate, osteoporosis, and cognitive defects
    • Leoyklang P, et al. (2007) Heterozygous nonsense mutation SATB2 associated with cleft palate, osteoporosis, and cognitive defects. Hum Mutat 28:732-738.
    • (2007) Hum Mutat , vol.28 , pp. 732-738
    • Leoyklang, P.1
  • 27
    • 33748999278 scopus 로고    scopus 로고
    • Satb2 haploinsufficiency phenocopies 2q32-q33 deletions, whereas loss suggests a fundamental role in the coordination of jaw development
    • Britanova O, et al. (2006) Satb2 haploinsufficiency phenocopies 2q32-q33 deletions, whereas loss suggests a fundamental role in the coordination of jaw development. Am J Hum Genet 79:668-678.
    • (2006) Am J Hum Genet , vol.79 , pp. 668-678
    • Britanova, O.1
  • 28
    • 0036333736 scopus 로고    scopus 로고
    • High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage
    • Geoffroy V, Kneissel M, Fournier B, Boyde A, Matthias P (2002) High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage. Mol Cell Biol 22:6222-6233.
    • (2002) Mol Cell Biol , vol.22 , pp. 6222-6233
    • Geoffroy, V.1    Kneissel, M.2    Fournier, B.3    Boyde, A.4    Matthias, P.5
  • 29
    • 70350125874 scopus 로고    scopus 로고
    • MicroRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma
    • Karbiener M, et al. (2009) microRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma. Blochem Biophys Res Commun 390:247-251.
    • (2009) Blochem Biophys Res Commun , vol.390 , pp. 247-251
    • Karbiener, M.1
  • 30
    • 76349089521 scopus 로고    scopus 로고
    • MiR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression
    • Kim SY, et al. (2010) miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression. Blochem Biophys Res Commun 392:323-328.
    • (2010) Blochem Biophys Res Commun , vol.392 , pp. 323-328
    • Kim, S.Y.1
  • 31
    • 33846027131 scopus 로고    scopus 로고
    • BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network
    • Hassan MQ, et al. (2006) BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network. J Biol Chem 281:40515-40526.
    • (2006) J Biol Chem , vol.281 , pp. 40515-40526
    • Hassan, M.Q.1
  • 32
    • 34250666701 scopus 로고    scopus 로고
    • Production and purification of lentiviral vectors
    • Tiscornia G, Singer O, Verma IM (2006) Production and purification of lentiviral vectors. Nat Protoc 1:241-245.
    • (2006) Nat Protoc , vol.1 , pp. 241-245
    • Tiscornia, G.1    Singer, O.2    Verma, I.M.3
  • 33
    • 77954113554 scopus 로고    scopus 로고
    • Ribonucleoprotein immunoprecipitation (RNP-IP): A direct in vivo analysis of microRNA-targets
    • Hassan MQ, et al. (2010) Ribonucleoprotein immunoprecipitation (RNP-IP): A direct in vivo analysis of microRNA-targets. J Cell Blochem 110:817-822.
    • (2010) J Cell Blochem , vol.110 , pp. 817-822
    • Hassan, M.Q.1


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