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Volumn 15, Issue 3, 2014, Pages

Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECANASE 1; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR RUNX2; PROTEIN BINDING; RUNX2 PROTEIN, MOUSE;

EID: 84899633354     PISSN: None     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2014-15-3-r52     Document Type: Article
Times cited : (124)

References (73)
  • 1
    • 79951792447 scopus 로고    scopus 로고
    • Signaling networks in RUNX2-dependent bone development
    • 10.1002/jcb.22994, 21328448
    • Komori T. Signaling networks in RUNX2-dependent bone development. J Cell Biochem 2011, 112:750-755. 10.1002/jcb.22994, 21328448.
    • (2011) J Cell Biochem , vol.112 , pp. 750-755
    • Komori, T.1
  • 3
    • 84255200563 scopus 로고    scopus 로고
    • Building strong bones: molecular regulation of the osteoblast lineage
    • Long F. Building strong bones: molecular regulation of the osteoblast lineage. Nat Rev Mol Cell Biol 2012, 13:27-38.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 27-38
    • Long, F.1
  • 4
    • 0036186852 scopus 로고    scopus 로고
    • Mutations in the RUNX2 gene in patients with cleidocranial dysplasia
    • 10.1002/humu.10043, 11857736
    • Otto F, Kanegane H, Mundlos S. Mutations in the RUNX2 gene in patients with cleidocranial dysplasia. Hum Mutat 2002, 19:209-216. 10.1002/humu.10043, 11857736.
    • (2002) Hum Mutat , vol.19 , pp. 209-216
    • Otto, F.1    Kanegane, H.2    Mundlos, S.3
  • 6
    • 33748170578 scopus 로고    scopus 로고
    • Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation
    • 10.1016/j.bone.2006.04.024, 16774856
    • Vaes BL, Ducy P, Sijbers AM, Hendriks JM, van Someren EP, de Jong NG, van den Heuvel ER, Olijve W, van Zoelen EJ, Dechering KJ. Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation. Bone 2006, 39:724-738. 10.1016/j.bone.2006.04.024, 16774856.
    • (2006) Bone , vol.39 , pp. 724-738
    • Vaes, B.L.1    Ducy, P.2    Sijbers, A.M.3    Hendriks, J.M.4    van Someren, E.P.5    de Jong, N.G.6    van den Heuvel, E.R.7    Olijve, W.8    van Zoelen, E.J.9    Dechering, K.J.10
  • 7
    • 0038607705 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-gamma inhibits the Runx2-mediated transcription of osteocalcin in osteoblasts
    • 10.1074/jbc.M211610200, 12704187
    • Jeon MJ, Kim JA, Kwon SH, Kim SW, Park KS, Park SW, Kim SY, Shin CS. Activation of peroxisome proliferator-activated receptor-gamma inhibits the Runx2-mediated transcription of osteocalcin in osteoblasts. J Biol Chem 2003, 278:23270-23277. 10.1074/jbc.M211610200, 12704187.
    • (2003) J Biol Chem , vol.278 , pp. 23270-23277
    • Jeon, M.J.1    Kim, J.A.2    Kwon, S.H.3    Kim, S.W.4    Park, K.S.5    Park, S.W.6    Kim, S.Y.7    Shin, C.S.8
  • 8
    • 84860344707 scopus 로고    scopus 로고
    • Down-regulation of type I Runx2 mediated by dexamethasone is required for 3T3-L1 adipogenesis
    • 10.1210/me.2011-1287, 22422618
    • Zhang YY, Li X, Qian SW, Guo L, Huang HY, He Q, Liu Y, Ma CG, Tang QQ. Down-regulation of type I Runx2 mediated by dexamethasone is required for 3T3-L1 adipogenesis. Mol Endocrinol 2012, 26:798-808. 10.1210/me.2011-1287, 22422618.
    • (2012) Mol Endocrinol , vol.26 , pp. 798-808
    • Zhang, Y.Y.1    Li, X.2    Qian, S.W.3    Guo, L.4    Huang, H.Y.5    He, Q.6    Liu, Y.7    Ma, C.G.8    Tang, Q.Q.9
  • 9
    • 4744366089 scopus 로고    scopus 로고
    • Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype
    • 10.1016/j.yexcr.2004.07.031, 15475005
    • Gersbach CA, Byers BA, Pavlath GK, Garcia AJ. Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype. Exp Cell Res 2004, 300:406-417. 10.1016/j.yexcr.2004.07.031, 15475005.
    • (2004) Exp Cell Res , vol.300 , pp. 406-417
    • Gersbach, C.A.1    Byers, B.A.2    Pavlath, G.K.3    Garcia, A.J.4
  • 10
    • 26844574658 scopus 로고    scopus 로고
    • Runx2: a master organizer of gene transcription in developing and maturing osteoblasts
    • 10.1002/bdrc.20043, 16187316
    • Schroeder TM, Jensen ED, Westendorf JJ. Runx2: a master organizer of gene transcription in developing and maturing osteoblasts. Birth Defects Res C Embryo Today 2005, 75:213-225. 10.1002/bdrc.20043, 16187316.
    • (2005) Birth Defects Res C Embryo Today , vol.75 , pp. 213-225
    • Schroeder, T.M.1    Jensen, E.D.2    Westendorf, J.J.3
  • 12
    • 80755136753 scopus 로고    scopus 로고
    • Hdac-mediated control of endochondral and intramembranous ossification
    • 10.1615/CritRevEukarGeneExpr.v21.i2.10, 3218555, 22077150
    • Bradley EW, McGee-Lawrence ME, Westendorf JJ. Hdac-mediated control of endochondral and intramembranous ossification. Crit Rev Eukaryot Gene Expr 2011, 21:101-113. 10.1615/CritRevEukarGeneExpr.v21.i2.10, 3218555, 22077150.
    • (2011) Crit Rev Eukaryot Gene Expr , vol.21 , pp. 101-113
    • Bradley, E.W.1    McGee-Lawrence, M.E.2    Westendorf, J.J.3
  • 13
    • 0037129340 scopus 로고    scopus 로고
    • MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2
    • 10.1038/sj.onc.1205367, 11965546
    • Pelletier N, Champagne N, Stifani S, Yang XJ. MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2. Oncogene 2002, 21:2729-2740. 10.1038/sj.onc.1205367, 11965546.
    • (2002) Oncogene , vol.21 , pp. 2729-2740
    • Pelletier, N.1    Champagne, N.2    Stifani, S.3    Yang, X.J.4
  • 14
    • 33747343713 scopus 로고    scopus 로고
    • Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity
    • 10.1074/jbc.M511640200, 16772287
    • Villagra A, Cruzat F, Carvallo L, Paredes R, Olate J, van Wijnen AJ, Stein GS, Lian JB, Stein JL, Imbalzano AN, Montecino M. Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity. J Biol Chem 2006, 281:22695-22706. 10.1074/jbc.M511640200, 16772287.
    • (2006) J Biol Chem , vol.281 , pp. 22695-22706
    • Villagra, A.1    Cruzat, F.2    Carvallo, L.3    Paredes, R.4    Olate, J.5    van Wijnen, A.J.6    Stein, G.S.7    Lian, J.B.8    Stein, J.L.9    Imbalzano, A.N.10    Montecino, M.11
  • 16
    • 77957220857 scopus 로고    scopus 로고
    • Comparative epigenomic analysis of murine and human adipogenesis
    • 10.1016/j.cell.2010.09.006, 2950833, 20887899
    • Mikkelsen TS, Xu Z, Zhang X, Wang L, Gimble JM, Lander ES, Rosen ED. Comparative epigenomic analysis of murine and human adipogenesis. Cell 2010, 143:156-169. 10.1016/j.cell.2010.09.006, 2950833, 20887899.
    • (2010) Cell , vol.143 , pp. 156-169
    • Mikkelsen, T.S.1    Xu, Z.2    Zhang, X.3    Wang, L.4    Gimble, J.M.5    Lander, E.S.6    Rosen, E.D.7
  • 18
    • 84859157183 scopus 로고    scopus 로고
    • Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity
    • 10.1016/j.cell.2012.01.056, 3336965, 22500808
    • Zhang JA, Mortazavi A, Williams BA, Wold BJ, Rothenberg EV. Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity. Cell 2012, 149:467-482. 10.1016/j.cell.2012.01.056, 3336965, 22500808.
    • (2012) Cell , vol.149 , pp. 467-482
    • Zhang, J.A.1    Mortazavi, A.2    Williams, B.A.3    Wold, B.J.4    Rothenberg, E.V.5
  • 20
    • 0032983542 scopus 로고    scopus 로고
    • Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential
    • 10.1359/jbmr.1999.14.6.893, 10352097
    • Wang D, Christensen K, Chawla K, Xiao G, Krebsbach PH, Franceschi RT. Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. J Bone Miner Res 1999, 14:893-903. 10.1359/jbmr.1999.14.6.893, 10352097.
    • (1999) J Bone Miner Res , vol.14 , pp. 893-903
    • Wang, D.1    Christensen, K.2    Chawla, K.3    Xiao, G.4    Krebsbach, P.H.5    Franceschi, R.T.6
  • 21
    • 0029984140 scopus 로고    scopus 로고
    • Expression patterns of bone-related proteins during osteoblastic differentiation in MC3T3-E1 cells
    • 10.1002/(SICI)1097-4644(19960616)61:4<609::AID-JCB15>3.0.CO;2-A, 8806085
    • Choi JY, Lee BH, Song KB, Park RW, Kim IS, Sohn KY, Jo JS, Ryoo HM. Expression patterns of bone-related proteins during osteoblastic differentiation in MC3T3-E1 cells. J Cell Biochem 1996, 61:609-618. 10.1002/(SICI)1097-4644(19960616)61:4<609::AID-JCB15>3.0.CO;2-A, 8806085.
    • (1996) J Cell Biochem , vol.61 , pp. 609-618
    • Choi, J.Y.1    Lee, B.H.2    Song, K.B.3    Park, R.W.4    Kim, I.S.5    Sohn, K.Y.6    Jo, J.S.7    Ryoo, H.M.8
  • 23
    • 33846057724 scopus 로고    scopus 로고
    • NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins
    • 10.1093/nar/gkl842, 1716718, 17130148
    • Pruitt KD, Tatusova T, Maglott DR. NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res 2007, 35:D61-D65. 10.1093/nar/gkl842, 1716718, 17130148.
    • (2007) Nucleic Acids Res , vol.35
    • Pruitt, K.D.1    Tatusova, T.2    Maglott, D.R.3
  • 25
    • 84866108697 scopus 로고    scopus 로고
    • Genome-wide studies of CCCTC-binding factor (CTCF) and cohesin provide insight into chromatin structure and regulation
    • 10.1074/jbc.R111.324962, 3438923, 22952237
    • Lee BK, Iyer VR. Genome-wide studies of CCCTC-binding factor (CTCF) and cohesin provide insight into chromatin structure and regulation. J Biol Chem 2012, 287:30906-30913. 10.1074/jbc.R111.324962, 3438923, 22952237.
    • (2012) J Biol Chem , vol.287 , pp. 30906-30913
    • Lee, B.K.1    Iyer, V.R.2
  • 27
    • 78650511231 scopus 로고    scopus 로고
    • CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells
    • 10.1038/ncb2139, 3076036, 21131960
    • Wei Y, Chen YH, Li LY, Lang J, Yeh SP, Shi B, Yang CC, Yang JY, Lin CY, Lai CC, Hung MC. CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells. Nat Cell Biol 2011, 13:87-94. 10.1038/ncb2139, 3076036, 21131960.
    • (2011) Nat Cell Biol , vol.13 , pp. 87-94
    • Wei, Y.1    Chen, Y.H.2    Li, L.Y.3    Lang, J.4    Yeh, S.P.5    Shi, B.6    Yang, C.C.7    Yang, J.Y.8    Lin, C.Y.9    Lai, C.C.10    Hung, M.C.11
  • 29
    • 84899638170 scopus 로고    scopus 로고
    • PeaksToGenes
    • PeaksToGenes. [https://github.com/peakstogenes/PeaksToGenes].
  • 30
    • 84862963292 scopus 로고    scopus 로고
    • Discovering transcription factor regulatory targets using gene expression and binding data
    • 10.1093/bioinformatics/btr628, 3259433, 22084256
    • Maienschein-Cline M, Zhou J, White KP, Sciammas R, Dinner AR. Discovering transcription factor regulatory targets using gene expression and binding data. Bioinformatics 2012, 28:206-213. 10.1093/bioinformatics/btr628, 3259433, 22084256.
    • (2012) Bioinformatics , vol.28 , pp. 206-213
    • Maienschein-Cline, M.1    Zhou, J.2    White, K.P.3    Sciammas, R.4    Dinner, A.R.5
  • 31
    • 0038349948 scopus 로고    scopus 로고
    • Sequencing and comparison of yeast species to identify genes and regulatory elements
    • 10.1038/nature01644, 12748633
    • Kellis M, Patterson N, Endrizzi M, Birren B, Lander ES. Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 2003, 423:241-254. 10.1038/nature01644, 12748633.
    • (2003) Nature , vol.423 , pp. 241-254
    • Kellis, M.1    Patterson, N.2    Endrizzi, M.3    Birren, B.4    Lander, E.S.5
  • 35
    • 77952000649 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP
    • 10.1074/jbc.M109.052001, 2863178, 20223822
    • Qiu W, Hu Y, Andersen TE, Jafari A, Li N, Chen W, Kassem M. Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP. J Biol Chem 2010, 285:14438-14449. 10.1074/jbc.M109.052001, 2863178, 20223822.
    • (2010) J Biol Chem , vol.285 , pp. 14438-14449
    • Qiu, W.1    Hu, Y.2    Andersen, T.E.3    Jafari, A.4    Li, N.5    Chen, W.6    Kassem, M.7
  • 37
    • 33745218499 scopus 로고    scopus 로고
    • Analysis of fracture healing by large-scale transcriptional profile identified temporal relationships between metalloproteinase and ADAMTS mRNA expression
    • 10.1016/j.matbio.2006.02.001, 16584876
    • Wang K, Vishwanath P, Eichler GS, Al-Sebaei MO, Edgar CM, Einhorn TA, Smith TF, Gerstenfeld LC. Analysis of fracture healing by large-scale transcriptional profile identified temporal relationships between metalloproteinase and ADAMTS mRNA expression. Matrix Biol 2006, 25:271-281. 10.1016/j.matbio.2006.02.001, 16584876.
    • (2006) Matrix Biol , vol.25 , pp. 271-281
    • Wang, K.1    Vishwanath, P.2    Eichler, G.S.3    Al-Sebaei, M.O.4    Edgar, C.M.5    Einhorn, T.A.6    Smith, T.F.7    Gerstenfeld, L.C.8
  • 39
    • 0035122861 scopus 로고    scopus 로고
    • Gene array analysis of osteoblast differentiation
    • Beck GR, Zerler B, Moran E. Gene array analysis of osteoblast differentiation. Cell Growth Differ 2001, 12:61-83.
    • (2001) Cell Growth Differ , vol.12 , pp. 61-83
    • Beck, G.R.1    Zerler, B.2    Moran, E.3
  • 40
    • 77957937697 scopus 로고    scopus 로고
    • Signaling pathways in human skeletal dysplasias
    • 10.1146/annurev-genom-082908-150158, 20690819
    • Baldridge D, Shchelochkov O, Kelley B, Lee B. Signaling pathways in human skeletal dysplasias. Annu Rev Genomics Hum Genet 2010, 11:189-217. 10.1146/annurev-genom-082908-150158, 20690819.
    • (2010) Annu Rev Genomics Hum Genet , vol.11 , pp. 189-217
    • Baldridge, D.1    Shchelochkov, O.2    Kelley, B.3    Lee, B.4
  • 41
    • 84655173624 scopus 로고    scopus 로고
    • Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells
    • 10.1101/gr.127597.111, 3246210, 22090374
    • Lee BK, Bhinge AA, Battenhouse A, McDaniell RM, Liu Z, Song L, Ni Y, Birney E, Lieb JD, Furey TS, Crawford GE, Iyer VR. Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells. Genome Res 2012, 22:9-24. 10.1101/gr.127597.111, 3246210, 22090374.
    • (2012) Genome Res , vol.22 , pp. 9-24
    • Lee, B.K.1    Bhinge, A.A.2    Battenhouse, A.3    McDaniell, R.M.4    Liu, Z.5    Song, L.6    Ni, Y.7    Birney, E.8    Lieb, J.D.9    Furey, T.S.10    Crawford, G.E.11    Iyer, V.R.12
  • 44
    • 68949213578 scopus 로고    scopus 로고
    • Insights from genomic profiling of transcription factors
    • 10.1038/nrg2636, 2846386, 19668247
    • Farnham PJ. Insights from genomic profiling of transcription factors. Nat Rev Genet 2009, 10:605-616. 10.1038/nrg2636, 2846386, 19668247.
    • (2009) Nat Rev Genet , vol.10 , pp. 605-616
    • Farnham, P.J.1
  • 46
    • 77955629953 scopus 로고    scopus 로고
    • Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation
    • 10.1128/MCB.00118-10, 2916448, 20547749
    • Stender JD, Kim K, Charn TH, Komm B, Chang KC, Kraus WL, Benner C, Glass CK, Katzenellenbogen BS. Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation. Mol Cell Biol 2010, 30:3943-3955. 10.1128/MCB.00118-10, 2916448, 20547749.
    • (2010) Mol Cell Biol , vol.30 , pp. 3943-3955
    • Stender, J.D.1    Kim, K.2    Charn, T.H.3    Komm, B.4    Chang, K.C.5    Kraus, W.L.6    Benner, C.7    Glass, C.K.8    Katzenellenbogen, B.S.9
  • 49
    • 79960876540 scopus 로고    scopus 로고
    • A high resolution genome-wide scan of HNF4alpha recognition sites infers a regulatory gene network in colon cancer
    • 10.1371/journal.pone.0021667, 3145629, 21829439
    • Weltmeier F, Borlak J. A high resolution genome-wide scan of HNF4alpha recognition sites infers a regulatory gene network in colon cancer. PLoS One 2011, 6:e21667. 10.1371/journal.pone.0021667, 3145629, 21829439.
    • (2011) PLoS One , vol.6
    • Weltmeier, F.1    Borlak, J.2
  • 50
    • 84860354838 scopus 로고    scopus 로고
    • Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion
    • 10.1093/nar/gkr1219, 3333873, 22187159
    • Little GH, Noushmehr H, Baniwal SK, Berman BP, Coetzee GA, Frenkel B. Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion. Nucleic Acids Res 2012, 40:3538-3547. 10.1093/nar/gkr1219, 3333873, 22187159.
    • (2012) Nucleic Acids Res , vol.40 , pp. 3538-3547
    • Little, G.H.1    Noushmehr, H.2    Baniwal, S.K.3    Berman, B.P.4    Coetzee, G.A.5    Frenkel, B.6
  • 51
    • 0035079804 scopus 로고    scopus 로고
    • Stein GS: runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins
    • 10.1128/MCB.21.8.2891-2905.2001, 86918, 11283267
    • Javed A, Barnes GL, Jasanya BO, Stein JL, Gerstenfeld L, Lian JB. Stein GS: runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins. Mol Cell Biol 2001, 21:2891-2905. 10.1128/MCB.21.8.2891-2905.2001, 86918, 11283267.
    • (2001) Mol Cell Biol , vol.21 , pp. 2891-2905
    • Javed, A.1    Barnes, G.L.2    Jasanya, B.O.3    Stein, J.L.4    Gerstenfeld, L.5    Lian, J.B.6
  • 52
    • 4744369224 scopus 로고    scopus 로고
    • Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells
    • 10.1128/MCB.24.20.8847-8861.2004, 517904, 15456860
    • Paredes R, Arriagada G, Cruzat F, Villagra A, Olate J, Zaidi K, van Wijnen A, Lian JB, Stein GS, Stein JL, Montecino M. Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells. Mol Cell Biol 2004, 24:8847-8861. 10.1128/MCB.24.20.8847-8861.2004, 517904, 15456860.
    • (2004) Mol Cell Biol , vol.24 , pp. 8847-8861
    • Paredes, R.1    Arriagada, G.2    Cruzat, F.3    Villagra, A.4    Olate, J.5    Zaidi, K.6    van Wijnen, A.7    Lian, J.B.8    Stein, G.S.9    Stein, J.L.10    Montecino, M.11
  • 53
    • 22544476244 scopus 로고    scopus 로고
    • Tissue- and bone cell-specific expression of bone sialoprotein is directed by a 9.0 kb promoter in transgenic mice
    • 10.1016/j.matbio.2005.05.009, 15970437
    • Paz J, Wade K, Kiyoshima T, Sodek J, Tang J, Tu Q, Yamauchi M, Chen J. Tissue- and bone cell-specific expression of bone sialoprotein is directed by a 9.0 kb promoter in transgenic mice. Matrix Biol 2005, 24:341-352. 10.1016/j.matbio.2005.05.009, 15970437.
    • (2005) Matrix Biol , vol.24 , pp. 341-352
    • Paz, J.1    Wade, K.2    Kiyoshima, T.3    Sodek, J.4    Tang, J.5    Tu, Q.6    Yamauchi, M.7    Chen, J.8
  • 54
    • 24744451966 scopus 로고    scopus 로고
    • Cooperative interactions between RUNX2 and homeodomain protein-binding sites are critical for the osteoblast-specific expression of the bone sialoprotein gene
    • 10.1074/jbc.M503942200, 16000302
    • Roca H, Phimphilai M, Gopalakrishnan R, Xiao G, Franceschi RT. Cooperative interactions between RUNX2 and homeodomain protein-binding sites are critical for the osteoblast-specific expression of the bone sialoprotein gene. J Biol Chem 2005, 280:30845-30855. 10.1074/jbc.M503942200, 16000302.
    • (2005) J Biol Chem , vol.280 , pp. 30845-30855
    • Roca, H.1    Phimphilai, M.2    Gopalakrishnan, R.3    Xiao, G.4    Franceschi, R.T.5
  • 59
    • 0034789271 scopus 로고    scopus 로고
    • A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene
    • Zaidi SK, Javed A, Choi JY, van Wijnen AJ, Stein JL, Lian JB, Stein GS. A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene. J Cell Sci 2001, 114:3093-3102.
    • (2001) J Cell Sci , vol.114 , pp. 3093-3102
    • Zaidi, S.K.1    Javed, A.2    Choi, J.Y.3    van Wijnen, A.J.4    Stein, J.L.5    Lian, J.B.6    Stein, G.S.7
  • 61
    • 84899652845 scopus 로고    scopus 로고
    • FoxPrimer qPCR Primer Design Suite
    • FoxPrimer qPCR Primer Design Suite. [http://www.foxprimer.org].
  • 62
    • 84899626720 scopus 로고    scopus 로고
    • Nuclear organization in breast cance
    • UMASS Medical School
    • Dobson JR. Nuclear organization in breast cance. PhD thesis 2013, UMASS Medical School.
    • (2013) PhD thesis
    • Dobson, J.R.1
  • 63
    • 54249097017 scopus 로고    scopus 로고
    • Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells
    • 10.1158/0008-5472.CAN-08-1078, 2596479, 18829534
    • Pratap J, Wixted JJ, Gaur T, Zaidi SK, Dobson J, Gokul KD, Hussain S, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells. Cancer Res 2008, 68:7795-7802. 10.1158/0008-5472.CAN-08-1078, 2596479, 18829534.
    • (2008) Cancer Res , vol.68 , pp. 7795-7802
    • Pratap, J.1    Wixted, J.J.2    Gaur, T.3    Zaidi, S.K.4    Dobson, J.5    Gokul, K.D.6    Hussain, S.7    van Wijnen, A.J.8    Stein, J.L.9    Stein, G.S.10    Lian, J.B.11
  • 64
    • 79951780811 scopus 로고    scopus 로고
    • R: A Language and Environment for Statistical Computing
    • R: A Language and Environment for Statistical Computing. [http://www.R-project.org].
  • 65
    • 1342288026 scopus 로고    scopus 로고
    • Affy-analysis of Affymetrix GeneChip data at the probe level
    • 10.1093/bioinformatics/btg405, 14960456
    • Gautier L, Cope L, Bolstad BM, Irizarry RA. affy-analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 2004, 20:307-315. 10.1093/bioinformatics/btg405, 14960456.
    • (2004) Bioinformatics , vol.20 , pp. 307-315
    • Gautier, L.1    Cope, L.2    Bolstad, B.M.3    Irizarry, R.A.4
  • 67
    • 33644872577 scopus 로고    scopus 로고
    • Limma: linear models for microarray data
    • New York: Springer, Gentleman R, Carey VJ, Huber W, Irizarry RA, Dudoit S, [Gail M, Krickeberg K, Samet J, Tsiatis A, Wong W (Series Editors): Statistics for Biology and Health]
    • Smyth GK. Limma: linear models for microarray data. Bioinformatics and Computational Biology Solutions Using R and Bioconductor 2005, 397-420. New York: Springer, Gentleman R, Carey VJ, Huber W, Irizarry RA, Dudoit S, [Gail M, Krickeberg K, Samet J, Tsiatis A, Wong W (Series Editors): Statistics for Biology and Health].
    • (2005) Bioinformatics and Computational Biology Solutions Using R and Bioconductor , pp. 397-420
    • Smyth, G.K.1
  • 68
    • 0001677717 scopus 로고
    • Controlling the false discovery rate - a practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate - a practical and powerful approach to multiple testing. J R Stat Soc Series B Methodol 1995, 57:289-300.
    • (1995) J R Stat Soc Series B Methodol , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 69
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • 10.1093/nar/11.5.1475, 325809, 6828386
    • Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983, 11:1475-1489. 10.1093/nar/11.5.1475, 325809, 6828386.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 70
    • 84863139254 scopus 로고    scopus 로고
    • Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility
    • 10.1074/jbc.M111.287771, 3281617, 22158627
    • van der Deen M, Akech J, Lapointe D, Gupta S, Young DW, Montecino MA, Galindo M, Lian JB, Stein JL, Stein GS, van Wijnen AJ. Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility. J Biol Chem 2012, 287:4503-4517. 10.1074/jbc.M111.287771, 3281617, 22158627.
    • (2012) J Biol Chem , vol.287 , pp. 4503-4517
    • van der Deen, M.1    Akech, J.2    Lapointe, D.3    Gupta, S.4    Young, D.W.5    Montecino, M.A.6    Galindo, M.7    Lian, J.B.8    Stein, J.L.9    Stein, G.S.10    van Wijnen, A.J.11
  • 71
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • 10.1186/gb-2009-10-3-r25, 2690996, 19261174
    • Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 2009, 10:R25. 10.1186/gb-2009-10-3-r25, 2690996, 19261174.
    • (2009) Genome Biol , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 72
    • 0036079158 scopus 로고    scopus 로고
    • The human genome browser at UCSC
    • 10.1101/gr.229102. Article published online before print in May 2002, 186604, 12045153
    • Kent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, Zahler AM, Haussler D. The human genome browser at UCSC. Genome Res 2002, 12:996-1006. 10.1101/gr.229102. Article published online before print in May 2002, 186604, 12045153.
    • (2002) Genome Res , vol.12 , pp. 996-1006
    • Kent, W.J.1    Sugnet, C.W.2    Furey, T.S.3    Roskin, K.M.4    Pringle, T.H.5    Zahler, A.M.6    Haussler, D.7


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