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Volumn 52, Issue 3, 2014, Pages

MicroRNAs and post-transcriptional regulation of skeletal development

Author keywords

BMPs; Bone; Cell differentiation; Chondroblasts; miRNAs; Osteoblasts; Osteoclasts; Signal transduction; Wnt

Indexed keywords

MICRORNA;

EID: 84899760651     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-13-0294     Document Type: Review
Times cited : (66)

References (169)
  • 1
    • 78649390537 scopus 로고    scopus 로고
    • Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro
    • doi:10.1093/rheumatology/keq247
    • Abouheif MM, Nakasa T, Shibuya H, Niimoto T, Kongcharoensombat W & Ochi M 2010 Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro. Rheumatology 49 2054-2060. (doi:10.1093/rheumatology/keq247)
    • (2010) Rheumatology , vol.49 , pp. 2054-2060
    • Abouheif, M.M.1    Nakasa, T.2    Shibuya, H.3    Niimoto, T.4    Kongcharoensombat, W.5    Ochi, M.6
  • 2
    • 84860918355 scopus 로고    scopus 로고
    • MicroRNA-199a* regulates the expression of cyclooxygenase-2 in human chondrocytes
    • doi:10.1136/annrheumdis-2011-200519
    • Akhtar N & Haqqi TM 2012 MicroRNA-199a* regulates the expression of cyclooxygenase-2 in human chondrocytes. Annals of the Rheumatic Diseases 71 1073-1080. (doi:10.1136/annrheumdis-2011-200519)
    • (2012) Annals of the Rheumatic Diseases , vol.71 , pp. 1073-1080
    • Akhtar, N.1    Haqqi, T.M.2
  • 3
    • 77951743715 scopus 로고    scopus 로고
    • MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes
    • doi:10.1002/art.27329
    • Akhtar N, Rasheed Z, Ramamurthy S, Anbazhagan AN, Voss FR & Haqqi TM 2010 MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes. Arthritis and Rheumatism 62 1361-1371. (doi:10.1002/art.27329)
    • (2010) Arthritis and Rheumatism , vol.62 , pp. 1361-1371
    • Akhtar, N.1    Rasheed, Z.2    Ramamurthy, S.3    Anbazhagan, A.N.4    Voss, F.R.5    Haqqi, T.M.6
  • 4
    • 0036830491 scopus 로고    scopus 로고
    • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
    • doi:10.1101/ gad.1017802
    • Akiyama H, Chaboissier MC, Martin JF, Schedl A & de Crombrugghe B 2002 The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes and Development 16 2813-2828. (doi:10.1101/ gad.1017802)
    • (2002) Genes and Development , vol.16 , pp. 2813-2828
    • Akiyama, H.1    Chaboissier, M.C.2    Martin, J.F.3    Schedl, A.4    de Crombrugghe, B.5
  • 6
    • 77953038244 scopus 로고    scopus 로고
    • MicroRNA-140 and the silencing of osteoarthritis
    • doi:10.1101/ gad.1939310
    • Araldi E & Schipani E 2010 MicroRNA-140 and the silencing of osteoarthritis. Genes and Development 24 1075-1080. (doi:10.1101/ gad.1939310)
    • (2010) Genes and Development , vol.24 , pp. 1075-1080
    • Araldi, E.1    Schipani, E.2
  • 8
    • 0034933057 scopus 로고    scopus 로고
    • Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow
    • doi:10.1038/35083081
    • Bafico A, Liu G, Yaniv A, Gazit A & Aaronson SA 2001 Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nature Cell Biology 3 683-686. (doi:10.1038/35083081)
    • (2001) Nature Cell Biology , vol.3 , pp. 683-686
    • Bafico, A.1    Liu, G.2    Yaniv, A.3    Gazit, A.4    Aaronson, S.A.5
  • 9
    • 85027948268 scopus 로고    scopus 로고
    • MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31
    • doi:10.1016/j.gene.2013.06.021
    • Baglio SR, Devescovi V, Granchi D & Baldini N 2013 MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31. Gene 527 321-331. (doi:10.1016/j.gene.2013.06.021)
    • (2013) Gene , vol.527 , pp. 321-331
    • Baglio, S.R.1    Devescovi, V.2    Granchi, D.3    Baldini, N.4
  • 10
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • doi:10.1016/S0092-8674(04)00045-5
    • Bartel DP 2004 MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 281-297. (doi:10.1016/S0092-8674(04)00045-5)
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 12
    • 0035810951 scopus 로고    scopus 로고
    • Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization
    • doi:10.1073/pnas.111092198
    • Bi W, Huang W, Whitworth DJ, Deng JM, Zhang Z, Behringer RR & de Crombrugghe B 2001 Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization. PNAS 98 6698-6703. (doi:10.1073/pnas.111092198)
    • (2001) PNAS , vol.98 , pp. 6698-6703
    • Bi, W.1    Huang, W.2    Whitworth, D.J.3    Deng, J.M.4    Zhang, Z.5    Behringer, R.R.6    de Crombrugghe, B.7
  • 16
    • 14944375271 scopus 로고    scopus 로고
    • Novel transcription factor Satb2 interacts with matrix attachment region DNA elements in a tissue-specific manner and demonstrates cell-typedependent expression in the developing mouse CNS
    • doi:10.1111/j.1460-9568.2005. 03897.x
    • Britanova O, Akopov S, Lukyanov S, Gruss P & Tarabykin V 2005 Novel transcription factor Satb2 interacts with matrix attachment region DNA elements in a tissue-specific manner and demonstrates cell-typedependent expression in the developing mouse CNS. European Journal of Neuroscience 21 658-668. (doi:10.1111/j.1460-9568.2005. 03897.x)
    • (2005) European Journal of Neuroscience , vol.21 , pp. 658-668
    • Britanova, O.1    Akopov, S.2    Lukyanov, S.3    Gruss, P.4    Tarabykin, V.5
  • 17
    • 24744462930 scopus 로고    scopus 로고
    • BMP-2 and insulin-like growth factor-I mediate Osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways
    • doi:10.1074/jbc.M503845200
    • Celil AB & Campbell PG 2005 BMP-2 and insulin-like growth factor-I mediate Osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways. Journal of Biological Chemistry 280 31353-31359. (doi:10.1074/jbc.M503845200)
    • (2005) Journal of Biological Chemistry , vol.280 , pp. 31353-31359
    • Celil, A.B.1    Campbell, P.G.2
  • 18
    • 23844506742 scopus 로고    scopus 로고
    • Osx transcriptional regulation is mediated by additional pathways to BMP2/Smad signaling
    • doi:10.1002/jcb.20429
    • Celil AB, Hollinger JO & Campbell PG 2005 Osx transcriptional regulation is mediated by additional pathways to BMP2/Smad signaling. Journal of Cellular Biochemistry 95 518-528. (doi:10.1002/jcb.20429)
    • (2005) Journal of Cellular Biochemistry , vol.95 , pp. 518-528
    • Celil, A.B.1    Hollinger, J.O.2    Campbell, P.G.3
  • 19
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • doi:10.1126/ science.1091903
    • Chen CZ, Li L, Lodish HF & Bartel DP 2004 MicroRNAs modulate hematopoietic lineage differentiation. Science 303 83-86. (doi:10.1126/ science.1091903)
    • (2004) Science , vol.303 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3    Bartel, D.P.4
  • 20
    • 84874623866 scopus 로고    scopus 로고
    • Identification and characterization of microRNAs controlled by the osteoblast-specific transcription factor Osterix
    • doi:10.1371/journal.pone.0058104
    • Chen Q, Liu W, Sinha KM, Yasuda H & de Crombrugghe B 2013a Identification and characterization of microRNAs controlled by the osteoblast-specific transcription factor Osterix. PLoS ONE 8 e58104. (doi:10.1371/journal.pone.0058104)
    • (2013) PLoS ONE , vol.8
    • Chen, Q.1    Liu, W.2    Sinha, K.M.3    Yasuda, H.4    de Crombrugghe, B.5
  • 22
    • 84879463172 scopus 로고    scopus 로고
    • SATB2 is a novel marker of osteoblastic differentiation in bone and soft tissue tumours
    • doi:10.1111/his.12138
    • Conner JR & Hornick JL 2013 SATB2 is a novel marker of osteoblastic differentiation in bone and soft tissue tumours. Histopathology 63 36-49. (doi:10.1111/his.12138)
    • (2013) Histopathology , vol.63 , pp. 36-49
    • Conner, J.R.1    Hornick, J.L.2
  • 24
    • 84871892801 scopus 로고    scopus 로고
    • Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes
    • doi:10.1186/ar4114
    • Dai L, Zhang X, Hu X, Zhou C & Ao Y 2012 Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes. Arthritis Research & Therapy 14 R268. (doi:10.1186/ar4114)
    • (2012) Arthritis Research & Therapy , vol.14
    • Dai, L.1    Zhang, X.2    Hu, X.3    Zhou, C.4    Ao, Y.5
  • 25
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • doi:10.1038/nature07086
    • Davis BN, Hilyard AC, Lagna G & Hata A 2008 SMAD proteins control DROSHA-mediated microRNA maturation. Nature 454 56-61. (doi:10.1038/nature07086)
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 26
    • 77955484492 scopus 로고    scopus 로고
    • Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
    • doi:10.1016/ j.molcel.2010.07.011
    • Davis BN, Hilyard AC, Nguyen PH, Lagna G & Hata A 2010 Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Molecular Cell 39 373-384. (doi:10.1016/ j.molcel.2010.07.011) Davis-Dusenbery BN & Hata A 2010 Mechanisms of control of microRNA biogenesis. Journal of Biochemistry 148 381-392. (doi:10.1093/jb/ mvq096)
    • (2010) Molecular Cell , vol.39 , pp. 373-384
    • Davis, B.N.1    Hilyard, A.C.2    Nguyen, P.H.3    Lagna, G.4    Hata, A.5
  • 27
    • 77958050722 scopus 로고    scopus 로고
    • Mechanisms of control of microRNA biogenesis
    • doi:10.1093/jb/ mvq096
    • Davis-Dusenbery BN & Hata A 2010 Mechanisms of control of microRNA biogenesis. Journal of Biochemistry 148 381-392. (doi:10.1093/jb/mvq096)
    • (2010) Journal of Biochemistry , vol.148 , pp. 381-392
    • Davis-Dusenbery, B.N.1    Hata, A.2
  • 28
    • 84881157835 scopus 로고    scopus 로고
    • Effects of a miR-31, Runx2, and Satb2 regulatory loop on the osteogenic differentiation of bone mesenchymal stem cells
    • doi:10.1089/scd.2012.0686
    • Deng Y, Wu S, Zhou H, Bi X, Wang Y, Hu Y, Gu P & Fan X 2013 Effects of a miR-31, Runx2, and Satb2 regulatory loop on the osteogenic differentiation of bone mesenchymal stem cells. Stem Cells and Development 22 2278-2286. (doi:10.1089/scd.2012.0686) Diaz-Prado S, Cicione C, Muinos-Lopez E, Hermida-Gomez T, Oreiro N, Fernandez-Lopez C & Blanco FJ 2012 Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes. BMC Musculoskeletal Disorders 13 144. (doi:10.1186/1471-2474-13-144)
    • (2013) Stem Cells and Development , vol.22 , pp. 2278-2286
    • Deng, Y.1    Wu, S.2    Zhou, H.3    Bi, X.4    Wang, Y.5    Hu, Y.6    Gu, P.7    Fan, X.8
  • 30
    • 33744536200 scopus 로고    scopus 로고
    • SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation
    • doi:10.1016/j.cell.2006.05.012
    • Dobreva G, Chahrour M, Dautzenberg M, Chirivella L, Kanzler B, Farinas I, Karsenty G & Grosschedl R 2006 SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell 125 971-986. (doi:10.1016/j.cell.2006.05.012)
    • (2006) Cell , vol.125 , pp. 971-986
    • Dobreva, G.1    Chahrour, M.2    Dautzenberg, M.3    Chirivella, L.4    Kanzler, B.5    Farinas, I.6    Karsenty, G.7    Grosschedl, R.8
  • 31
    • 0033662188 scopus 로고    scopus 로고
    • Cbfa1: A molecular switch in osteoblast biology
    • doi:10.1002/1097-0177(2000)9999:9999
    • Ducy P 2000 Cbfa1: a molecular switch in osteoblast biology. Developmental Dynamics 219 461-471. (doi:10.1002/1097-0177(2000)9999:9999
    • (2000) Developmental Dynamics , vol.219 , pp. 461-471
    • Ducy, P.1
  • 32
    • 0028927556 scopus 로고
    • Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene
    • Ducy P & Karsenty G 1995 Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene. Molecular and Cellular Biology 15 1858-1869.
    • (1995) Molecular and Cellular Biology , vol.15 , pp. 1858-1869
    • Ducy, P.1    Karsenty, G.2
  • 33
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • doi:10.1016/S0092-8674(00)80257-3
    • Ducy P, Zhang R, Geoffroy V, Ridall AL & Karsenty G 1997 Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89 747-754. (doi:10.1016/S0092-8674(00)80257-3)
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 34
    • 0035224984 scopus 로고    scopus 로고
    • Regulation of osteoclast formation and function
    • doi:10.1023/A:1010063225902
    • Duong LT & Rodan GA 2001 Regulation of osteoclast formation and function. Reviews in Endocrine & Metabolic Disorders 2 95-104. (doi:10.1023/A:1010063225902)
    • (2001) Reviews in Endocrine & Metabolic Disorders , vol.2 , pp. 95-104
    • Duong, L.T.1    Rodan, G.A.2
  • 35
    • 84875338307 scopus 로고    scopus 로고
    • OstemiR: A novel panel of microRNA biomarkers in osteoblastic and osteocytic differentiation from mesencymal stem cells
    • doi:10.1371/journal.pone.0058796
    • Eguchi T, Watanabe K, Hara ES, Ono M, Kuboki T & Calderwood SK 2013 OstemiR: a novel panel of microRNA biomarkers in osteoblastic and osteocytic differentiation from mesencymal stem cells. PLoS ONE 8 e58796. (doi:10.1371/journal.pone.0058796)
    • (2013) PLoS ONE , vol.8
    • Eguchi, T.1    Watanabe, K.2    Hara, E.S.3    Ono, M.4    Kuboki, T.5    Calderwood, S.K.6
  • 36
    • 84885368280 scopus 로고    scopus 로고
    • Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis
    • doi:10.1016/j.ccr.2013.09.008
    • Ell B, Mercatali L, Ibrahim T, Campbell N, Schwarzenbach H, Pantel K, Amadori D & Kang Y 2013 Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis. Cancer Cell 24 542-556. (doi:10.1016/j.ccr.2013.09.008)
    • (2013) Cancer Cell , vol.24 , pp. 542-556
    • Ell, B.1    Mercatali, L.2    Ibrahim, T.3    Campbell, N.4    Schwarzenbach, H.5    Pantel, K.6    Amadori, D.7    Kang, Y.8
  • 38
    • 84887851454 scopus 로고    scopus 로고
    • miR-29 promotes murine osteoclastogenesis by regulating osteoclast commitment and migration
    • doi:10.1074/jbc.M113.484568
    • Franceschetti T, Kessler CB, Lee SK & Delany AM 2013 miR-29 promotes murine osteoclastogenesis by regulating osteoclast commitment and migration. Journal of Biological Chemistry 288 33347-33360. (doi:10.1074/jbc.M113.484568)
    • (2013) Journal of Biological Chemistry , vol.288 , pp. 33347-33360
    • Franceschetti, T.1    Kessler, C.B.2    Lee, S.K.3    Delany, A.M.4
  • 39
    • 34247483919 scopus 로고    scopus 로고
    • An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling
    • (doi:10.1016/j.cell.2007.02.048)
    • Fukao T, Fukuda Y, Kiga K, Sharif J, Hino K, Enomoto Y, Kawamura A, Nakamura K, Takeuchi T & TanabeM2007 An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling. Cell 129 617-631. (doi:10.1016/j.cell.2007.02.048)
    • (2007) Cell , vol.129 , pp. 617-631
    • Fukao, T.1    Fukuda, Y.2    Kiga, K.3    Sharif, J.4    Hino, K.5    Enomoto, Y.6    Kawamura, A.7    Nakamura, K.8    Takeuchi, T.9    Tanabe, M.10
  • 40
    • 59349086946 scopus 로고    scopus 로고
    • BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity
    • doi:10.1242/jcs.031286
    • Gamell C, Osses N, Bartrons R, Ruckle T, Camps M, Rosa JL & Ventura F 2008 BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity. Journal of Cell Science 121 3960-3970. (doi:10.1242/jcs.031286)
    • (2008) Journal of Cell Science , vol.121 , pp. 3960-3970
    • Gamell, C.1    Osses, N.2    Bartrons, R.3    Ruckle, T.4    Camps, M.5    Rosa, J.L.6    Ventura, F.7
  • 41
    • 84877892009 scopus 로고    scopus 로고
    • MicroRNA-322 (miR-322) and its target protein Tob2 modulate Osterix (Osx) mRNA stability
    • doi:10.1074/jbc.M112.432104
    • Gamez B, Rodriguez-Carballo E, Bartrons R, Rosa JL & Ventura F 2013 MicroRNA-322 (miR-322) and its target protein Tob2 modulate Osterix (Osx) mRNA stability. Journal of Biological Chemistry 288 14264-14275. (doi:10.1074/jbc.M112.432104)
    • (2013) Journal of Biological Chemistry , vol.288 , pp. 14264-14275
    • Gamez, B.1    Rodriguez-Carballo, E.2    Bartrons, R.3    Rosa, J.L.4    Ventura, F.5
  • 42
    • 80051484363 scopus 로고    scopus 로고
    • MicroRNA expression during osteogenic differentiation of human multipotent mesenchymal stromal cells from bone marrow
    • doi:10.1002/jcb.23106
    • Gao J, Yang T, Han J, Yan K, Qiu X, Zhou Y, Fan Q & Ma B 2011 MicroRNA expression during osteogenic differentiation of human multipotent mesenchymal stromal cells from bone marrow. Journal of Cellular Biochemistry 112 1844-1856. (doi:10.1002/jcb.23106)
    • (2011) Journal of Cellular Biochemistry , vol.112 , pp. 1844-1856
    • Gao, J.1    Yang, T.2    Han, J.3    Yan, K.4    Qiu, X.5    Zhou, Y.6    Fan, Q.7    Ma, B.8
  • 44
    • 77649187445 scopus 로고    scopus 로고
    • Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse
    • doi:10.1016/j.ydbio. 2010.01.008
    • Gaur T, Hussain S, Mudhasani R, Parulkar I, Colby JL, FrederickD, Kream BE, van Wijnen AJ, Stein JL, Stein GS et al. 2010 Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse. Developmental Biology 340 10-21. (doi:10.1016/j.ydbio. 2010.01.008)
    • (2010) Developmental Biology , vol.340 , pp. 10-21
    • Gaur, T.1    Hussain, S.2    Mudhasani, R.3    Parulkar, I.4    Colby, J.L.5    Frederick, D.6    Kream, B.E.7    van Wijnen, A.J.8    Stein, J.L.9    Stein, G.S.10
  • 45
    • 84881025936 scopus 로고    scopus 로고
    • MicroRNAs and cartilage
    • doi:10.1002/jor.22397
    • Gibson G & Asahara H 2013 MicroRNAs and cartilage. Journal of Orthopaedic Research 31 1333-1344. (doi:10.1002/jor.22397)
    • (2013) Journal of Orthopaedic Research , vol.31 , pp. 1333-1344
    • Gibson, G.1    Asahara, H.2
  • 46
    • 15444381042 scopus 로고    scopus 로고
    • RANKmediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis
    • doi:10.1038/ sj.emboj.7600564
    • Gohda J, Akiyama T, Koga T, Takayanagi H, Tanaka S & Inoue J 2005 RANKmediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis. EMBO Journal 24 790-799. (doi:10.1038/ sj.emboj.7600564)
    • (2005) EMBO Journal , vol.24 , pp. 790-799
    • Gohda, J.1    Akiyama, T.2    Koga, T.3    Takayanagi, H.4    Tanaka, S.5    Inoue, J.6
  • 47
    • 82655181357 scopus 로고    scopus 로고
    • MiR-365: A mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4
    • doi:10.1096/ fj.11-185132
    • Guan YJ, Yang X, Wei L & Chen Q 2011 MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4. FASEB Journal 25 4457-4466. (doi:10.1096/ fj.11-185132)
    • (2011) FASEB Journal , vol.25 , pp. 4457-4466
    • Guan, Y.J.1    Yang, X.2    Wei, L.3    Chen, Q.4
  • 48
    • 84876580853 scopus 로고    scopus 로고
    • Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cells
    • doi:10.1371/journal.pone.0062582
    • Guerit D, Philipot D, Chuchana P, Toupet K, Brondello JM, Mathieu M, Jorgensen C & Noel D 2013 Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cells. PLoS ONE 8 e62582. (doi:10.1371/journal.pone.0062582)
    • (2013) PLoS ONE , vol.8
    • Guerit, D.1    Philipot, D.2    Chuchana, P.3    Toupet, K.4    Brondello, J.M.5    Mathieu, M.6    Jorgensen, C.7    Noel, D.8
  • 49
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • doi:10.1038/nature09267
    • Guo H, Ingolia NT, Weissman JS & Bartel DP 2010 Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466 835-840. (doi:10.1038/nature09267)
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 50
    • 33744520104 scopus 로고    scopus 로고
    • Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
    • doi:10.1016/j.cell.2006.03.043
    • Han J, Lee Y, Yeom KH, Nam JW, Heo I, Rhee JK, Sohn SY, Cho Y, Zhang BT & Kim VN 2006 Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125 887-901. (doi:10.1016/j.cell.2006.03.043)
    • (2006) Cell , vol.125 , pp. 887-901
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Nam, J.W.4    Heo, I.5    Rhee, J.K.6    Sohn, S.Y.7    Cho, Y.8    Zhang, B.T.9    Kim, V.N.10
  • 51
    • 78650548873 scopus 로고    scopus 로고
    • A network connecting Runx2, SATB2, and the miR-23a-27a-24-2 cluster regulates the osteoblast differentiation program
    • doi:10.1073/pnas.1007698107
    • Hassan MQ, Gordon JA, Beloti MM, Croce CM, van Wijnen AJ, Stein JL, Stein GS & Lian JB 2010 A network connecting Runx2, SATB2, and the miR-23a-27a-24-2 cluster regulates the osteoblast differentiation program. PNAS 107 19879-19884. (doi:10.1073/pnas.1007698107)
    • (2010) PNAS , vol.107 , pp. 19879-19884
    • Hassan, M.Q.1    Gordon, J.A.2    Beloti, M.M.3    Croce, C.M.4    van Wijnen, A.J.5    Stein, J.L.6    Stein, G.S.7    Lian, J.B.8
  • 53
    • 65249179717 scopus 로고    scopus 로고
    • MicroRNAs and micromanaging the skeleton in disease, development and evolution
    • doi:10.1111/j.1582-4934.2009. 00696.x
    • He X, Eberhart JK & Postlethwait JH 2009 MicroRNAs and micromanaging the skeleton in disease, development and evolution. Journal of Cellular and Molecular Medicine 13 606-618. (doi:10.1111/j.1582-4934.2009. 00696.x)
    • (2009) Journal of Cellular and Molecular Medicine , vol.13 , pp. 606-618
    • He, X.1    Eberhart, J.K.2    Postlethwait, J.H.3
  • 54
    • 78149418638 scopus 로고    scopus 로고
    • miRNA-mediated functional changes through co-regulating function related genes
    • doi:10.1371/journal.pone. 0013558
    • He J, Zhang JF, Yi C, Lv Q, Xie WD, Li JN, Wan G, Cui K, Kung HF, Yang J et al. 2010 miRNA-mediated functional changes through co-regulating function related genes. PLoS ONE 5 e13558. (doi:10.1371/journal.pone. 0013558)
    • (2010) PLoS ONE , vol.5
    • He, J.1    Zhang, J.F.2    Yi, C.3    Lv, Q.4    Xie, W.D.5    Li, J.N.6    Wan, G.7    Cui, K.8    Kung, H.F.9    Yang, J.10
  • 55
    • 41349096445 scopus 로고    scopus 로고
    • Gene regulation by transcription factors and microRNAs
    • doi:10.1126/science.1151651
    • Hobert O 2008 Gene regulation by transcription factors and microRNAs. Science 319 1785-1786. (doi:10.1126/science.1151651)
    • (2008) Science , vol.319 , pp. 1785-1786
    • Hobert, O.1
  • 56
    • 0035070302 scopus 로고    scopus 로고
    • Control of osteoclastogenesis and bone resorption by members of the TNF family of receptors and ligands
    • doi:10.1016/ S1359-6101(00)00030-7
    • Horowitz MC, Xi Y, Wilson K & Kacena MA 2001 Control of osteoclastogenesis and bone resorption by members of the TNF family of receptors and ligands. Cytokine & Growth Factor Reviews 12 9-18. (doi:10.1016/ S1359-6101(00)00030-7)
    • (2001) Cytokine & Growth Factor Reviews , vol.12 , pp. 9-18
    • Horowitz, M.C.1    Xi, Y.2    Wilson, K.3    Kacena, M.A.4
  • 58
    • 84873814382 scopus 로고    scopus 로고
    • miR1423p promotes osteoblast differentiation by modulating Wnt signaling
    • doi:10.3892/mmr.2012.1207
    • Hu W, Ye Y, Zhang W, Wang J, Chen A & Guo F 2013 miR1423p promotes osteoblast differentiation by modulating Wnt signaling. Molecular Medicine Reports 7 689-693. (doi:10.3892/mmr.2012.1207)
    • (2013) Molecular Medicine Reports , vol.7 , pp. 689-693
    • Hu, W.1    Ye, Y.2    Zhang, W.3    Wang, J.4    Chen, A.5    Guo, F.6
  • 59
    • 77149136767 scopus 로고    scopus 로고
    • MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation
    • doi:10.1002/stem.288
    • Huang J, Zhao L, Xing L & Chen D 2010 MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation. Stem Cells 28 357-364. (doi:10.1002/stem.288)
    • (2010) Stem Cells , vol.28 , pp. 357-364
    • Huang, J.1    Zhao, L.2    Xing, L.3    Chen, D.4
  • 60
    • 56649084972 scopus 로고    scopus 로고
    • Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks
    • doi:10.1371/journal.pone.0003740
    • Iliopoulos D, Malizos KN, Oikonomou P & Tsezou A 2008 Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS ONE 3 e3740. (doi:10.1371/journal.pone.0003740)
    • (2008) PLoS ONE , vol.3
    • Iliopoulos, D.1    Malizos, K.N.2    Oikonomou, P.3    Tsezou, A.4
  • 62
    • 67749145694 scopus 로고    scopus 로고
    • MicroRNA-141 and-200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5
    • doi:10.1074/jbc.M109.014001
    • Itoh T, Nozawa Y & Akao Y 2009 MicroRNA-141 and-200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5. Journal of Biological Chemistry 284 19272-19279. (doi:10.1074/jbc.M109.014001)
    • (2009) Journal of Biological Chemistry , vol.284 , pp. 19272-19279
    • Itoh, T.1    Nozawa, Y.2    Akao, Y.3
  • 64
    • 0031858666 scopus 로고    scopus 로고
    • Hoxa-2 restricts the chondrogenic domain and inhibits bone formation during development of the branchial area
    • Kanzler B, Kuschert SJ, Liu YH & Mallo M 1998 Hoxa-2 restricts the chondrogenic domain and inhibits bone formation during development of the branchial area. Development 125 2587-2597.
    • (1998) Development , vol.125 , pp. 2587-2597
    • Kanzler, B.1    Kuschert, S.J.2    Liu, Y.H.3    Mallo, M.4
  • 65
    • 82155163802 scopus 로고    scopus 로고
    • MicroRNA biogenesis and regulation of bone remodeling
    • doi:10.1186/ar3325
    • Kapinas K & Delany AM 2011 MicroRNA biogenesis and regulation of bone remodeling. Arthritis Research & Therapy 13 220. (doi:10.1186/ar3325)
    • (2011) Arthritis Research & Therapy , vol.13 , pp. 220
    • Kapinas, K.1    Delany, A.M.2
  • 66
    • 69249143283 scopus 로고    scopus 로고
    • miR-29 suppression of osteonectin in osteoblasts: Regulation during differentiation and by canonical Wnt signaling
    • doi:10.1002/jcb.22243
    • Kapinas K, Kessler CB & Delany AM 2009 miR-29 suppression of osteonectin in osteoblasts: regulation during differentiation and by canonical Wnt signaling. Journal of Cellular Biochemistry 108 216-224. (doi:10.1002/jcb.22243)
    • (2009) Journal of Cellular Biochemistry , vol.108 , pp. 216-224
    • Kapinas, K.1    Kessler, C.B.2    Delany, A.M.3
  • 67
    • 77955492538 scopus 로고    scopus 로고
    • miR-29 modulates Wnt signaling in human osteoblasts through a positive feedback loop
    • doi:10. 1074/jbc.M110.116137
    • Kapinas K, Kessler C, Ricks T, Gronowicz G & Delany AM 2010 miR-29 modulates Wnt signaling in human osteoblasts through a positive feedback loop. Journal of Biological Chemistry 285 25221-25231. (doi:10. 1074/jbc.M110.116137)
    • (2010) Journal of Biological Chemistry , vol.285 , pp. 25221-25231
    • Kapinas, K.1    Kessler, C.2    Ricks, T.3    Gronowicz, G.4    Delany, A.M.5
  • 68
    • 84893062283 scopus 로고    scopus 로고
    • MicroRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN
    • doi:10.1089/scd.2013. 0209
    • Karlsen TA, Jakobsen RB, Mikkelsen TS & Brinchmann JE 2013 MicroRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN. Stem Cells and Development 23 290-304. (doi:10.1089/scd.2013. 0209)
    • (2013) Stem Cells and Development , vol.23 , pp. 290-304
    • Karlsen, T.A.1    Jakobsen, R.B.2    Mikkelsen, T.S.3    Brinchmann, J.E.4
  • 69
    • 52949136599 scopus 로고    scopus 로고
    • Transcriptional control of skeletogenesis
    • doi:10.1146/annurev.genom. 9.081307.164437
    • Karsenty G 2008 Transcriptional control of skeletogenesis. Annual Review of Genomics and Human Genetics 9 183-196. (doi:10.1146/annurev.genom. 9.081307.164437)
    • (2008) Annual Review of Genomics and Human Genetics , vol.9 , pp. 183-196
    • Karsenty, G.1
  • 70
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • doi:10.1016/S1534-5807(02)00157-0
    • Karsenty G & Wagner EF 2002 Reaching a genetic and molecular understanding of skeletal development. Developmental Cell 2 389-406. (doi:10.1016/S1534-5807(02)00157-0)
    • (2002) Developmental Cell , vol.2 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 71
    • 0033035286 scopus 로고    scopus 로고
    • Cbfa1 as a regulator of osteoblast differentiation and function
    • doi:10.1016/S8756-3282(99)00111-8
    • Karsenty G, Ducy P, StarbuckM, Priemel M, Shen J, Geoffroy V & AmlingM 1999 Cbfa1 as a regulator of osteoblast differentiation and function. Bone 25 107-108. (doi:10.1016/S8756-3282(99)00111-8)
    • (1999) Bone , vol.25 , pp. 107-108
    • Karsenty, G.1    Ducy, P.2    Starbuck, M.3    Priemel, M.4    Shen, J.5    Geoffroy, V.6    Amling, M.7
  • 73
    • 33748102321 scopus 로고    scopus 로고
    • Muscle-specific microRNA miR-206 promotes muscle differentiation
    • doi:10.1083/jcb.200603008
    • Kim HK, Lee YS, Sivaprasad U, Malhotra A & Dutta A 2006 Muscle-specific microRNA miR-206 promotes muscle differentiation. Journal of Cell Biology 174 677-687. (doi:10.1083/jcb.200603008)
    • (2006) Journal of Cell Biology , vol.174 , pp. 677-687
    • Kim, H.K.1    Lee, Y.S.2    Sivaprasad, U.3    Malhotra, A.4    Dutta, A.5
  • 74
    • 84855879238 scopus 로고    scopus 로고
    • MicroRNA-34a regulates migration of chondroblast and IL-1β-induced degeneration of chondrocytes by targeting EphA5
    • doi:10.1016/j.bbrc.2011.10.087
    • Kim D, Song J, Kim S, Chun CH & Jin EJ 2011 MicroRNA-34a regulates migration of chondroblast and IL-1β-induced degeneration of chondrocytes by targeting EphA5. Biochemical and Biophysical Research Communications 415 551-557. (doi:10.1016/j.bbrc.2011.10.087)
    • (2011) Biochemical and Biophysical Research Communications , vol.415 , pp. 551-557
    • Kim, D.1    Song, J.2    Kim, S.3    Chun, C.H.4    Jin, E.J.5
  • 75
    • 0035868884 scopus 로고    scopus 로고
    • Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis
    • doi:10.1093/emboj/20.6.1271
    • Kobayashi N, Kadono Y, Naito A, Matsumoto K, Yamamoto T, Tanaka S & Inoue J 2001 Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO Journal 20 1271-1280. (doi:10.1093/emboj/20.6.1271)
    • (2001) EMBO Journal , vol.20 , pp. 1271-1280
    • Kobayashi, N.1    Kadono, Y.2    Naito, A.3    Matsumoto, K.4    Yamamoto, T.5    Tanaka, S.6    Inoue, J.7
  • 77
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • doi:10.1016/S0092-8674(00)80258-5
    • Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao YH, Inada M et al. 1997 Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89 755-764. (doi:10.1016/S0092-8674(00)80258-5)
    • (1997) Cell , vol.89 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3    Yamaguchi, A.4    Sasaki, K.5    Deguchi, K.6    Shimizu, Y.7    Bronson, R.T.8    Gao, Y.H.9    Inada, M.10
  • 79
    • 84862562593 scopus 로고    scopus 로고
    • MicroRNAs miR-96, miR-124, and miR-199a regulate gene expression in human bone marrow-derived mesenchymal stem cells
    • doi:10.1002/jcb.24144
    • Laine SK, Alm JJ, Virtanen SP, Aro HT & Laitala-Leinonen TK 2012 MicroRNAs miR-96, miR-124, and miR-199a regulate gene expression in human bone marrow-derived mesenchymal stem cells. Journal of Cellular Biochemistry 113 2687-2695. (doi:10.1002/jcb.24144)
    • (2012) Journal of Cellular Biochemistry , vol.113 , pp. 2687-2695
    • Laine, S.K.1    Alm, J.J.2    Virtanen, S.P.3    Aro, H.T.4    Laitala-Leinonen, T.K.5
  • 83
    • 84881116940 scopus 로고    scopus 로고
    • MicroRNA-124 regulates osteoclast differentiation
    • doi:10.1016/ j.bone.2013.07.007
    • Lee Y, Kim HJ, Park CK, Kim YG, Lee HJ, Kim JY & Kim HH 2013 MicroRNA-124 regulates osteoclast differentiation. Bone 56 383-389. (doi:10.1016/ j.bone.2013.07.007)
    • (2013) Bone , vol.56 , pp. 383-389
    • Lee, Y.1    Kim, H.J.2    Park, C.K.3    Kim, Y.G.4    Lee, H.J.5    Kim, J.Y.6    Kim, H.H.7
  • 84
    • 0034846904 scopus 로고    scopus 로고
    • L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway
    • doi:10.1053/joca.2001. 0447
    • Lefebvre V, Behringer RR & de Crombrugghe B 2001 L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway. Osteoarthritis and Cartilage 9 (Suppl A) S69-S75. (doi:10.1053/joca.2001. 0447)
    • (2001) Osteoarthritis and Cartilage , vol.9 , Issue.SUPPL. A
    • Lefebvre, V.1    Behringer, R.R.2    de Crombrugghe, B.3
  • 85
    • 52949114558 scopus 로고    scopus 로고
    • A microRNA signature for a BMP2-induced osteoblast lineage commitment program
    • doi:10.1073/ pnas.0804438105
    • Li Z, Hassan MQ, Volinia S, van Wijnen AJ, Stein JL, Croce CM, Lian JB & Stein GS 2008 A microRNA signature for a BMP2-induced osteoblast lineage commitment program. PNAS 105 13906-13911. (doi:10.1073/ pnas.0804438105)
    • (2008) PNAS , vol.105 , pp. 13906-13911
    • Li, Z.1    Hassan, M.Q.2    Volinia, S.3    van Wijnen, A.J.4    Stein, J.L.5    Croce, C.M.6    Lian, J.B.7    Stein, G.S.8
  • 86
    • 72849121740 scopus 로고    scopus 로고
    • A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans
    • doi:10.1172/JCI39832
    • Li H, Xie H, Liu W, Hu R, Huang B, Tan YF, Xu K, Sheng ZF, Zhou HD, Wu XP et al. 2009a A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans. Journal of Clinical Investigation 119 3666-3677. (doi:10.1172/JCI39832)
    • (2009) Journal of Clinical Investigation , vol.119 , pp. 3666-3677
    • Li, H.1    Xie, H.2    Liu, W.3    Hu, R.4    Huang, B.5    Tan, Y.F.6    Xu, K.7    Sheng, Z.F.8    Zhou, H.D.9    Wu, X.P.10
  • 88
    • 79955890241 scopus 로고    scopus 로고
    • MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis
    • doi:10.1016/j.gene.2011.03.003
    • Li X, Gibson G, Kim JS, Kroin J, Xu S, van Wijnen AJ & Im HJ 2011 MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis. Gene 480 34-41. (doi:10.1016/j.gene.2011.03.003)
    • (2011) Gene , vol.480 , pp. 34-41
    • Li, X.1    Gibson, G.2    Kim, J.S.3    Kroin, J.4    Xu, S.5    van Wijnen, A.J.6    Im, H.J.7
  • 89
    • 84862513160 scopus 로고    scopus 로고
    • Down-regulation of miR-214 contributes to intrahepatic cholangiocarcinoma metastasis by targeting Twist
    • doi:10.1111/ j.1742-4658.2012.08618.x
    • Li B, Han Q, Zhu Y, Yu Y, Wang J & Jiang X 2012 Down-regulation of miR-214 contributes to intrahepatic cholangiocarcinoma metastasis by targeting Twist. FEBS Journal 279 2393-2398. (doi:10.1111/ j.1742-4658.2012.08618.x)
    • (2012) FEBS Journal , vol.279 , pp. 2393-2398
    • Li, B.1    Han, Q.2    Zhu, Y.3    Yu, Y.4    Wang, J.5    Jiang, X.6
  • 90
    • 84873659056 scopus 로고    scopus 로고
    • miR-17-5p and miR-106a are involved in the balance between osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells
    • doi:10.1016/ j.scr.2012.11.007
    • Li H, Li T, Wang S, Wei J, Fan J, Li J, Han Q, Liao L, Shao C & Zhao RC 2013 miR-17-5p and miR-106a are involved in the balance between osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells. Stem Cell Research 10 313-324. (doi:10.1016/ j.scr.2012.11.007)
    • (2013) Stem Cell Research , vol.10 , pp. 313-324
    • Li, H.1    Li, T.2    Wang, S.3    Wei, J.4    Fan, J.5    Li, J.6    Han, Q.7    Liao, L.8    Shao, C.9    Zhao, R.C.10
  • 91
    • 84876928351 scopus 로고    scopus 로고
    • Redundant miR-3077-5p and miR-705 mediate the shift of mesenchymal stem cell lineage commitment to adipocyte in osteoporosis bone marrow
    • doi:10.1038/cddis. 2013.130
    • Liao L, Yang X, Su X, Hu C, Zhu X, Yang N, Chen X, Shi S, Shi S & Jin Y 2013 Redundant miR-3077-5p and miR-705 mediate the shift of mesenchymal stem cell lineage commitment to adipocyte in osteoporosis bone marrow. Cell Death & Disease 4 e600. (doi:10.1038/cddis. 2013.130)
    • (2013) Cell Death & Disease , vol.4
    • Liao, L.1    Yang, X.2    Su, X.3    Hu, C.4    Zhu, X.5    Yang, N.6    Chen, X.7    Shi, S.8    Shi, S.9    Jin, Y.10
  • 92
    • 66449127376 scopus 로고    scopus 로고
    • miR-199a, a bone morphogenic protein 2-responsive microRNA, regulates chondrogenesis via direct targeting to Smad1
    • doi:10.1074/jbc.M807709200
    • Lin EA, Kong L, Bai XH, Luan Y & Liu CJ 2009 miR-199a, a bone morphogenic protein 2-responsive microRNA, regulates chondrogenesis via direct targeting to Smad1. Journal of Biological Chemistry 284 11326-11335. (doi:10.1074/jbc.M807709200)
    • (2009) Journal of Biological Chemistry , vol.284 , pp. 11326-11335
    • Lin, E.A.1    Kong, L.2    Bai, X.H.3    Luan, Y.4    Liu, C.J.5
  • 93
    • 0347988235 scopus 로고    scopus 로고
    • Nuclear export of microRNA precursors
    • doi:10.1126/science. 1090599
    • Lund E, Guttinger S, Calado A, Dahlberg JE & Kutay U 2004 Nuclear export of microRNA precursors. Science 303 95-98. (doi:10.1126/science. 1090599)
    • (2004) Science , vol.303 , pp. 95-98
    • Lund, E.1    Guttinger, S.2    Calado, A.3    Dahlberg, J.E.4    Kutay, U.5
  • 94
    • 38549101581 scopus 로고    scopus 로고
    • Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factor
    • doi:10.1359/jbmr.071011
    • Luzi E, Marini F, Sala SC, Tognarini I, Galli G & Brandi ML 2008 Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factor. Journal of Bone and Mineral Research 23 287-295. (doi:10.1359/jbmr.071011)
    • (2008) Journal of Bone and Mineral Research , vol.23 , pp. 287-295
    • Luzi, E.1    Marini, F.2    Sala, S.C.3    Tognarini, I.4    Galli, G.5    Brandi, M.L.6
  • 95
    • 34547441263 scopus 로고    scopus 로고
    • Target mRNAs are repressed as efficiently by microRNA-binding sites in the 50 UTR as in the 30 UTR
    • doi:10.1073/pnas.0703820104
    • Lytle JR, Yario TA & Steitz JA 2007 Target mRNAs are repressed as efficiently by microRNA-binding sites in the 50 UTR as in the 30 UTR. PNAS 104 9667-9672. (doi:10.1073/pnas.0703820104)
    • (2007) PNAS , vol.104 , pp. 9667-9672
    • Lytle, J.R.1    Yario, T.A.2    Steitz, J.A.3
  • 96
    • 77957664009 scopus 로고    scopus 로고
    • miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate
    • doi:10.1073/pnas.0915022107
    • Mann M, Barad O, Agami R, Geiger B & Hornstein E 2010 miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate. PNAS 107 15804-15809. (doi:10.1073/pnas.0915022107)
    • (2010) PNAS , vol.107 , pp. 15804-15809
    • Mann, M.1    Barad, O.2    Agami, R.3    Geiger, B.4    Hornstein, E.5
  • 97
    • 0034455103 scopus 로고    scopus 로고
    • Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
    • doi:10.1210/edrv.21.2. 0395
    • Manolagas SC 2000 Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocrine Reviews 21 115-137. (doi:10.1210/edrv.21.2. 0395) Martinez-Sanchez A & Murphy CL 2013 miR-1247 functions by targeting cartilage transcription factor SOX9. Journal of Biological Chemistry 288 30802-30814. (doi:10.1074/jbc.M113.496729) Martinez-Sanchez A, Dudek KA & Murphy CL 2012 Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145). Journal of Biological Chemistry 287 916-924. (doi:10.1074/jbc.M111.302430)
    • (2000) Endocrine Reviews , vol.21 , pp. 115-137
    • Manolagas, S.C.1
  • 98
    • 84886665132 scopus 로고    scopus 로고
    • miR-1247 functions by targeting cartilage transcription factor SOX9
    • doi:10.1074/jbc.M113.496729
    • Martinez-Sanchez A & Murphy CL 2013 miR-1247 functions by targeting cartilage transcription factor SOX9. Journal of Biological Chemistry 288 30802-30814. (doi:10.1074/jbc.M113.496729)
    • (2013) Journal of Biological Chemistry , vol.288 , pp. 30802-30814
    • Martinez-Sanchez, A.1    Murphy, C.L.2
  • 99
    • 84855502155 scopus 로고    scopus 로고
    • Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145)
    • doi:10.1074/jbc.M111.302430
    • Martinez-Sanchez A, Dudek KA & Murphy CL 2012 Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145). Journal of Biological Chemistry 287 916-924. (doi:10.1074/jbc.M111.302430)
    • (2012) Journal of Biological Chemistry , vol.287 , pp. 916-924
    • Martinez-Sanchez, A.1    Dudek, K.A.2    Murphy, C.L.3
  • 105
    • 75649127963 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptors and signal transduction
    • doi:10.1093/jb/mvp148
    • Miyazono K, Kamiya Y & Morikawa M 2010 Bone morphogenetic protein receptors and signal transduction. Journal of Biochemistry 147 35-51. (doi:10.1093/jb/mvp148)
    • (2010) Journal of Biochemistry , vol.147 , pp. 35-51
    • Miyazono, K.1    Kamiya, Y.2    Morikawa, M.3
  • 110
    • 0041923688 scopus 로고    scopus 로고
    • Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest
    • (doi:10.1073/pnas. 1631288100)
    • Mori-Akiyama Y, Akiyama H, Rowitch DH & de Crombrugghe B 2003 Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest. PNAS 100 9360-9365. (doi:10.1073/pnas. 1631288100)
    • (2003) PNAS , vol.100 , pp. 9360-9365
    • Mori-Akiyama, Y.1    Akiyama, H.2    Rowitch, D.H.3    de Crombrugghe, B.4
  • 111
    • 84870814111 scopus 로고    scopus 로고
    • The role of the 30UTR region in the regulation of the ACVR1/Alk-2 gene expression
    • doi:10.1371/journal.pone.0050958
    • Mura M, Cappato S, Giacopelli F, Ravazzolo R & Bocciardi R 2012 The role of the 30UTR region in the regulation of the ACVR1/Alk-2 gene expression. PLoS ONE 7 e50958. (doi:10.1371/journal.pone.0050958)
    • (2012) PLoS ONE , vol.7
    • Mura, M.1    Cappato, S.2    Giacopelli, F.3    Ravazzolo, R.4    Bocciardi, R.5
  • 112
    • 79960365689 scopus 로고    scopus 로고
    • Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling
    • doi:10.1128/MCB.05178-11
    • Nakamura Y, Inloes JB, Katagiri T& Kobayashi T 2011 Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling. Molecular and Cellular Biology 31 3019-3028. (doi:10.1128/MCB.05178-11)
    • (2011) Molecular and Cellular Biology , vol.31 , pp. 3019-3028
    • Nakamura, Y.1    Inloes, J.B.2    Katagiri, T.3    Kobayashi, T.4
  • 113
    • 0042204967 scopus 로고    scopus 로고
    • Transcriptional mechanisms in osteoblast differentiation and bone formation
    • doi:10.1016/S0168-9525(03)00176-8
    • Nakashima K & de Crombrugghe B 2003 Transcriptional mechanisms in osteoblast differentiation and bone formation. Trends in Genetics 19 458-466. (doi:10.1016/S0168-9525(03)00176-8)
    • (2003) Trends in Genetics , vol.19 , pp. 458-466
    • Nakashima, K.1    de Crombrugghe, B.2
  • 114
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
    • doi:10.1016/S0092-8674(01)00622-5
    • Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR & de Crombrugghe B 2002 The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108 17-29. (doi:10.1016/S0092-8674(01)00622-5)
    • (2002) Cell , vol.108 , pp. 17-29
    • Nakashima, K.1    Zhou, X.2    Kunkel, G.3    Zhang, Z.4    Deng, J.M.5    Behringer, R.R.6    de Crombrugghe, B.7
  • 116
    • 79960092538 scopus 로고    scopus 로고
    • mRNA expression profiling reveals conserved and non-conserved miR-140 targets
    • doi:10.4161/ rna.8.4.15390
    • Nicolas FE, Pais H, Schwach F, Lindow M, Kauppinen S, Moulton V & Dalmay T 2011 mRNA expression profiling reveals conserved and non-conserved miR-140 targets. RNA Biology 8 607-615. (doi:10.4161/ rna.8.4.15390)
    • (2011) RNA Biology , vol.8 , pp. 607-615
    • Nicolas, F.E.1    Pais, H.2    Schwach, F.3    Lindow, M.4    Kauppinen, S.5    Moulton, V.6    Dalmay, T.7
  • 117
    • 33646050013 scopus 로고    scopus 로고
    • Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene
    • doi:10.1016/j.gene.2005.12.022
    • Nishio Y, Dong Y, Paris M, O'Keefe RJ, Schwarz EM & Drissi H 2006 Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene. Gene 372 62-70. (doi:10.1016/j.gene.2005.12.022)
    • (2006) Gene , vol.372 , pp. 62-70
    • Nishio, Y.1    Dong, Y.2    Paris, M.3    O'Keefe, R.J.4    Schwarz, E.M.5    Drissi, H.6
  • 119
    • 77149122720 scopus 로고    scopus 로고
    • Analyzing mRNA expression identifies Smad3 as a microRNA-140 target regulated only at protein level
    • doi:10.1261/rna.1701210
    • Pais H, Nicolas FE, Soond SM, Swingler TE, Clark IM, Chantry A, Moulton V & Dalmay T 2010 Analyzing mRNA expression identifies Smad3 as a microRNA-140 target regulated only at protein level. RNA 16 489-494. (doi:10.1261/rna.1701210)
    • (2010) RNA , vol.16 , pp. 489-494
    • Pais, H.1    Nicolas, F.E.2    Soond, S.M.3    Swingler, T.E.4    Clark, I.M.5    Chantry, A.6    Moulton, V.7    Dalmay, T.8
  • 120
    • 84883311066 scopus 로고    scopus 로고
    • let-7 and miR-140 microRNAs coordinately regulate skeletal development
    • doi:10.1073/pnas.1302797110
    • Papaioannou G, Inloes JB, Nakamura Y, Paltrinieri E & Kobayashi T 2013 let-7 and miR-140 microRNAs coordinately regulate skeletal development. PNAS 110 E3291-E3300. (doi:10.1073/pnas.1302797110)
    • (2013) PNAS , vol.110
    • Papaioannou, G.1    Inloes, J.B.2    Nakamura, Y.3    Paltrinieri, E.4    Kobayashi, T.5
  • 121
    • 84889036617 scopus 로고    scopus 로고
    • MicroRNA-127-5p regulates matrix metalloproteinase 13 expression and interleukin-1β-induced catabolic effects in human chondrocytes
    • doi:10.1002/art.38188
    • Park SJ, Cheon EJ, Lee MH & Kim HA 2013 MicroRNA-127-5p regulates matrix metalloproteinase 13 expression and interleukin-1β-induced catabolic effects in human chondrocytes. Arthritis and Rheumatism 65 3141-3152. (doi:10.1002/art.38188)
    • (2013) Arthritis and Rheumatism , vol.65 , pp. 3141-3152
    • Park, S.J.1    Cheon, E.J.2    Lee, M.H.3    Kim, H.A.4
  • 122
    • 84870472401 scopus 로고    scopus 로고
    • Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation
    • doi:10.1016/j.celrep.2012.10.020
    • Pasero M, Giovarelli M, Bucci G, Gherzi R & Briata P 2012 Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation. Cell Reports 2 1159-1168. (doi:10.1016/j.celrep.2012.10.020)
    • (2012) Cell Reports , vol.2 , pp. 1159-1168
    • Pasero, M.1    Giovarelli, M.2    Bucci, G.3    Gherzi, R.4    Briata, P.5
  • 123
    • 84867625991 scopus 로고    scopus 로고
    • Beyond gap junctions: Connexin43 and bone cell signaling
    • doi:10.1016/j.bone.2012.09.030
    • Plotkin LI & Bellido T 2013 Beyond gap junctions: connexin43 and bone cell signaling. Bone 52 157-166. (doi:10.1016/j.bone.2012.09.030) Rodriguez-Carballo E, Ulsamer A, Susperregui AR, Manzanares-Cespedes C, Sanchez-Garcia E, Bartrons R, Rosa JL & Ventura F 2011 Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways. Journal of Bone and Mineral Research 26 718-729. (doi:10.1002/jbmr.260)
    • (2013) Bone , vol.52 , pp. 157-166
    • Plotkin, L.I.1    Bellido, T.2
  • 125
  • 126
    • 84901353644 scopus 로고    scopus 로고
    • The inflammatory circuitry of miR-149 as a pathological mechanism in osteoarthritis
    • [in press]. (doi:10.1007/ s00296-013-2754-8)
    • Santini P, Politi L, Vedova PD, Scandurra R & Scotto d'Abusco A 2013 The inflammatory circuitry of miR-149 as a pathological mechanism in osteoarthritis. Rheumatology International [in press]. (doi:10.1007/ s00296-013-2754-8)
    • (2013) Rheumatology International
    • Santini, P.1    Politi, L.2    Vedova, P.D.3    Scandurra, R.4    Scotto d'Abusco, A.5
  • 127
    • 64949115943 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 down-regulates miR-206 expression by blocking its maturation process
    • doi:10.1016/j.bbrc.2009.03.142
    • Sato MM, Nashimoto M, Katagiri T, Yawaka Y & Tamura M 2009 Bone morphogenetic protein-2 down-regulates miR-206 expression by blocking its maturation process. Biochemical and Biophysical Research Communications 383 125-129. (doi:10.1016/j.bbrc.2009.03.142)
    • (2009) Biochemical and Biophysical Research Communications , vol.383 , pp. 125-129
    • Sato, M.M.1    Nashimoto, M.2    Katagiri, T.3    Yawaka, Y.4    Tamura, M.5
  • 128
    • 33646939288 scopus 로고    scopus 로고
    • Rethinking the microprocessor
    • doi:10.1016/j.cell.2006.05.018
    • Seitz H & Zamore PD 2006 Rethinking the microprocessor. Cell 125 827-829. (doi:10.1016/j.cell.2006.05.018)
    • (2006) Cell , vol.125 , pp. 827-829
    • Seitz, H.1    Zamore, P.D.2
  • 129
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-β signaling from cell membrane to the nucleus
    • doi:10.1016/S0092-8674(03)00432-X
    • Shi Y & Massague J 2003 Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell 113 685-700. (doi:10.1016/S0092-8674(03)00432-X)
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 130
    • 84878931348 scopus 로고    scopus 로고
    • MicroRNA-214 suppresses osteogenic differentiation of C2C12 myoblast cells by targeting Osterix
    • doi:10.1016/j.bone.2013.04.002
    • Shi K, Lu J, Zhao Y, Wang L, Li J, Qi B, Li H & Ma C 2013 MicroRNA-214 suppresses osteogenic differentiation of C2C12 myoblast cells by targeting Osterix. Bone 55 487-494. (doi:10.1016/j.bone.2013.04.002)
    • (2013) Bone , vol.55 , pp. 487-494
    • Shi, K.1    Lu, J.2    Zhao, Y.3    Wang, L.4    Li, J.5    Qi, B.6    Li, H.7    Ma, C.8
  • 131
    • 84880787313 scopus 로고    scopus 로고
    • Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation
    • doi:10.3109/s10165-012-0710-1
    • Shibuya H, Nakasa T, Adachi N, Nagata Y, Ishikawa M, Deie M, Suzuki O & Ochi M 2013 Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation. Modern Rheumatology 23 674-685. (doi:10.3109/s10165-012-0710-1)
    • (2013) Modern Rheumatology , vol.23 , pp. 674-685
    • Shibuya, H.1    Nakasa, T.2    Adachi, N.3    Nagata, Y.4    Ishikawa, M.5    Deie, M.6    Suzuki, O.7    Ochi, M.8
  • 132
    • 84873468191 scopus 로고    scopus 로고
    • MicroRNA-181b regulates articular chondrocytes differentiation and cartilage integrity
    • doi:10.1016/j.bbrc.2012.12.133
    • Song J, Lee M, Kim D, Han J, Chun CH & Jin EJ 2013a MicroRNA-181b regulates articular chondrocytes differentiation and cartilage integrity. Biochemical and Biophysical Research Communications 431 210-214. (doi:10.1016/j.bbrc.2012.12.133)
    • (2013) Biochemical and Biophysical Research Communications , vol.431 , pp. 210-214
    • Song, J.1    Lee, M.2    Kim, D.3    Han, J.4    Chun, C.H.5    Jin, E.J.6
  • 133
    • 84877857624 scopus 로고    scopus 로고
    • MicroRNA-488 regulates zinc transporter SLC39A8/ZIP8 during pathogenesis of osteoarthritis
    • doi:10.1186/ 1423-0127-20-31
    • Song J, Kim D, Lee CH, Lee MS, Chun CH & Jin EJ 2013b MicroRNA-488 regulates zinc transporter SLC39A8/ZIP8 during pathogenesis of osteoarthritis. Journal of Biomedical Science 20 31. (doi:10.1186/ 1423-0127-20-31) Starega-Roslan J, Koscianska E, Kozlowski P & Krzyzosiak WJ 2011 The role of the precursor structure in the biogenesis of microRNA. Cellular and Molecular Life Sciences 68 2859-2871. (doi:10.1007/s00018-011-0726-2)
    • (2013) Journal of Biomedical Science , vol.20 , pp. 31
    • Song, J.1    Kim, D.2    Lee, C.H.3    Lee, M.S.4    Chun, C.H.5    Jin, E.J.6
  • 135
    • 34447262870 scopus 로고    scopus 로고
    • MicroRNA-223 is a key factor in osteoclast differentiation
    • doi:10.1002/jcb.21335
    • Sugatani T & Hruska KA 2007 MicroRNA-223 is a key factor in osteoclast differentiation. Journal of Cellular Biochemistry 101 996-999. (doi:10.1002/jcb.21335)
    • (2007) Journal of Cellular Biochemistry , vol.101 , pp. 996-999
    • Sugatani, T.1    Hruska, K.A.2
  • 136
    • 63249113375 scopus 로고    scopus 로고
    • Impaired micro-RNA pathways diminish osteoclast differentiation and function
    • doi:10.1074/jbc.M805777200
    • Sugatani T & Hruska KA 2009 Impaired micro-RNA pathways diminish osteoclast differentiation and function. Journal of Biological Chemistry 284 4667-4678. (doi:10.1074/jbc.M805777200)
    • (2009) Journal of Biological Chemistry , vol.284 , pp. 4667-4678
    • Sugatani, T.1    Hruska, K.A.2
  • 137
    • 79953686494 scopus 로고    scopus 로고
    • AmicroRNA expression signature of osteoclastogenesis
    • doi:10.1182/blood-2010-10-311415
    • Sugatani T, Vacher J & Hruska KA 2011 AmicroRNA expression signature of osteoclastogenesis. Blood 117 3648-3657. (doi:10.1182/blood-2010-10-311415)
    • (2011) Blood , vol.117 , pp. 3648-3657
    • Sugatani, T.1    Vacher, J.2    Hruska, K.A.3
  • 140
    • 18744366041 scopus 로고    scopus 로고
    • Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
    • doi:10.1016/S1534-5807(02)00369-6
    • Takayanagi H, Kim S, Koga T, Nishina H, Isshiki M, Yoshida H, Saiura A, Isobe M, Yokochi T, Inoue J et al. 2002 Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Developmental Cell 3 889-901. (doi:10.1016/S1534-5807(02)00369-6)
    • (2002) Developmental Cell , vol.3 , pp. 889-901
    • Takayanagi, H.1    Kim, S.2    Koga, T.3    Nishina, H.4    Isshiki, M.5    Yoshida, H.6    Saiura, A.7    Isobe, M.8    Yokochi, T.9    Inoue, J.10
  • 141
    • 28544452658 scopus 로고    scopus 로고
    • Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system
    • doi:10.1111/j.0105-2896.2005.00327.x
    • Tanaka S, Nakamura K, Takahasi N & Suda T 2005 Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system. Immunological Reviews 208 30-49. (doi:10.1111/j.0105-2896.2005.00327.x)
    • (2005) Immunological Reviews , vol.208 , pp. 30-49
    • Tanaka, S.1    Nakamura, K.2    Takahasi, N.3    Suda, T.4
  • 142
    • 84880121931 scopus 로고    scopus 로고
    • MicroRNA-145 downregulation associates with advanced tumor progression and poor prognosis in patients suffering osteosarcoma
    • (doi:10.2147/OTT.S40080)
    • Tang M, Lin L, Cai H, Tang J & Zhou Z 2013MicroRNA-145 downregulation associates with advanced tumor progression and poor prognosis in patients suffering osteosarcoma. OncoTargets and Therapy 6 833-838. (doi:10.2147/OTT.S40080)
    • (2013) OncoTargets and Therapy , vol.6 , pp. 833-838
    • Tang, M.1    Lin, L.2    Cai, H.3    Tang, J.4    Zhou, Z.5
  • 143
    • 73649139221 scopus 로고    scopus 로고
    • Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes
    • doi:10.1186/1471-2474-10-148
    • Tardif G, Hum D, Pelletier JP, Duval N & Martel-Pelletier J 2009 Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes. BMC Musculoskeletal Disorders 10 148. (doi:10.1186/1471-2474-10-148)
    • (2009) BMC Musculoskeletal Disorders , vol.10 , pp. 148
    • Tardif, G.1    Hum, D.2    Pelletier, J.P.3    Duval, N.4    Martel-Pelletier, J.5
  • 145
  • 147
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: MicroRNAs can up-regulate translation
    • doi:10.1126/science.1149460
    • Vasudevan S, Tong Y & Steitz JA 2007 Switching from repression to activation: microRNAs can up-regulate translation. Science 318 1931-1934. (doi:10.1126/science.1149460)
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 148
    • 77958086896 scopus 로고    scopus 로고
    • miR-27 promotes osteoblast differentiation by modulating Wnt signaling
    • doi:10.1016/j.bbrc.2010.08.031
    • Wang T & Xu Z 2010 miR-27 promotes osteoblast differentiation by modulating Wnt signaling. Biochemical and Biophysical Research Communications 402 186-189. (doi:10.1016/j.bbrc.2010.08.031)
    • (2010) Biochemical and Biophysical Research Communications , vol.402 , pp. 186-189
    • Wang, T.1    Xu, Z.2
  • 150
    • 84887426861 scopus 로고    scopus 로고
    • miR-30e reciprocally regulates the differentiation of adipocytes and osteoblasts by directly targeting low-density lipoprotein receptor-related protein 6
    • doi:10.1038/ cddis.2013.356
    • Wang J, Guan X, Guo F, Zhou J, Chang A, Sun B, Cai Y, Ma Z, Dai C, Li X et al. 2013b miR-30e reciprocally regulates the differentiation of adipocytes and osteoblasts by directly targeting low-density lipoprotein receptor-related protein 6. Cell Death & Disease 4 e845. (doi:10.1038/ cddis.2013.356)
    • (2013) Cell Death & Disease , vol.4
    • Wang, J.1    Guan, X.2    Guo, F.3    Zhou, J.4    Chang, A.5    Sun, B.6    Cai, Y.7    Ma, Z.8    Dai, C.9    Li, X.10
  • 152
    • 79954623314 scopus 로고    scopus 로고
    • TGF-β regulates miR-206 and miR-29 to control myogenic differentiation through regulation of HDAC4
    • doi:10.1074/jbc.M110.192625
    • Winbanks CE, Wang B, Beyer C, Koh P, White L, Kantharidis P & Gregorevic P 2011 TGF-β regulates miR-206 and miR-29 to control myogenic differentiation through regulation of HDAC4. Journal of Biological Chemistry 286 13805-13814. (doi:10.1074/jbc.M110.192625)
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 13805-13814
    • Winbanks, C.E.1    Wang, B.2    Beyer, C.3    Koh, P.4    White, L.5    Kantharidis, P.6    Gregorevic, P.7
  • 153
    • 0036830126 scopus 로고    scopus 로고
    • Ligand receptor interactions in the Wnt signaling pathway in Drosophila
    • doi:10.1074/jbc.M207850200
    • Wu CH & Nusse R 2002 Ligand receptor interactions in the Wnt signaling pathway in Drosophila. Journal of Biological Chemistry 277 41762-41769. (doi:10.1074/jbc.M207850200)
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 41762-41769
    • Wu, C.H.1    Nusse, R.2
  • 154
    • 84863263055 scopus 로고    scopus 로고
    • miR-30 family members negatively regulate osteoblast differentiation
    • doi:10.1074/jbc.M111.292722
    • Wu T, Zhou H, Hong Y, Li J, Jiang X & Huang H 2012 miR-30 family members negatively regulate osteoblast differentiation. Journal of Biological Chemistry 287 7503-7511. (doi:10.1074/jbc.M111.292722)
    • (2012) Journal of Biological Chemistry , vol.287 , pp. 7503-7511
    • Wu, T.1    Zhou, H.2    Hong, Y.3    Li, J.4    Jiang, X.5    Huang, H.6
  • 157
    • 80053235710 scopus 로고    scopus 로고
    • MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation
    • doi:10.1016/j.febslet.2011. 08.013
    • Yang J, Qin S, Yi C, Ma G, Zhu H, Zhou W, Xiong Y, Zhu X, Wang Y, He L et al. 2011 MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation. FEBS Letters 585 2992-2997. (doi:10.1016/j.febslet.2011. 08.013)
    • (2011) FEBS Letters , vol.585 , pp. 2992-2997
    • Yang, J.1    Qin, S.2    Yi, C.3    Ma, G.4    Zhu, H.5    Zhou, W.6    Xiong, Y.7    Zhu, X.8    Wang, Y.9    He, L.10
  • 159
    • 84882646974 scopus 로고    scopus 로고
    • Loss of microRNA-132 predicts poor prognosis in patients with primary osteosarcoma
    • doi:10.1007/s11010-013-1677-8
    • Yang J, Gao T, Tang J, Cai H, Lin L & Fu S 2013 Loss of microRNA-132 predicts poor prognosis in patients with primary osteosarcoma. Molecular and Cellular Biochemistry 381 9-15. (doi:10.1007/s11010-013-1677-8)
    • (2013) Molecular and Cellular Biochemistry , vol.381 , pp. 9-15
    • Yang, J.1    Gao, T.2    Tang, J.3    Cai, H.4    Lin, L.5    Fu, S.6
  • 160
    • 11144354938 scopus 로고    scopus 로고
    • Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog
    • doi:10.1101/gad.1174704
    • Yoshida CA, Yamamoto H, Fujita T, Furuichi T, Ito K, Inoue K, Yamana K, Zanma A, Takada K, Ito Y et al. 2004 Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog. Genes and Development 18 952-963. (doi:10.1101/gad.1174704)
    • (2004) Genes and Development , vol.18 , pp. 952-963
    • Yoshida, C.A.1    Yamamoto, H.2    Fujita, T.3    Furuichi, T.4    Ito, K.5    Inoue, K.6    Yamana, K.7    Zanma, A.8    Takada, K.9    Ito, Y.10
  • 163
    • 79960015376 scopus 로고    scopus 로고
    • A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2
    • doi:10. 1073/pnas.1018493108
    • Zhang Y, Xie RL, Croce CM, Stein JL, Lian JB, van Wijnen AJ & Stein GS 2011a A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2. PNAS 108 9863-9868. (doi:10. 1073/pnas.1018493108)
    • (2011) PNAS , vol.108 , pp. 9863-9868
    • Zhang, Y.1    Xie, R.L.2    Croce, C.M.3    Stein, J.L.4    Lian, J.B.5    van Wijnen, A.J.6    Stein, G.S.7
  • 166
    • 79960633240 scopus 로고    scopus 로고
    • Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1
    • doi:10.1002/jbmr.377
    • Zhang J, Tu Q, Bonewald LF, He X, Stein G, Lian J & Chen J 2011d Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1. Journal of Bone and Mineral Research 26 1953-1963. (doi:10.1002/jbmr.377)
    • (2011) Journal of Bone and Mineral Research , vol.26 , pp. 1953-1963
    • Zhang, J.1    Tu, Q.2    Bonewald, L.F.3    He, X.4    Stein, G.5    Lian, J.6    Chen, J.7
  • 167
  • 168
    • 84866596352 scopus 로고    scopus 로고
    • Interferon-β-induced miR-155 inhibits osteoclast differentiation by targeting SOCS1 and MITF
    • doi:10.1016/ j.febslet.2012.06.047
    • Zhang J, Zhao H, Chen J, Xia B, Jin Y, Wei W, Shen J & Huang Y 2012b Interferon-β-induced miR-155 inhibits osteoclast differentiation by targeting SOCS1 and MITF. FEBS Letters 586 3255-3262. (doi:10.1016/ j.febslet.2012.06.047)
    • (2012) FEBS Letters , vol.586 , pp. 3255-3262
    • Zhang, J.1    Zhao, H.2    Chen, J.3    Xia, B.4    Jin, Y.5    Wei, W.6    Shen, J.7    Huang, Y.8
  • 169
    • 77955602968 scopus 로고    scopus 로고
    • Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice
    • doi:10.1073/pnas.0912855107
    • Zhou X, Zhang Z, Feng JQ, Dusevich VM, Sinha K, Zhang H, Darnay BG & de Crombrugghe B 2010 Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice. PNAS 107 12919-12924. (doi:10.1073/pnas.0912855107)
    • (2010) PNAS , vol.107 , pp. 12919-12924
    • Zhou, X.1    Zhang, Z.2    Feng, J.Q.3    Dusevich, V.M.4    Sinha, K.5    Zhang, H.6    Darnay, B.G.7    de Crombrugghe, B.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.