SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2

Biochemistry

Volumn 48, Issue 30, 2009, Pages 7287-7295

  Cruzat, Fernando ^a   Henriquez, Berta ^a   Villagra, Alejandro ^a   Hepp, Matias ^a   Lian, Jane B ^b   Van Wijnen, Andre J ^b   Stein, Janet L ^b   Imbalzano, Anthony N ^b   Stein, Gary S ^b   Montecino, Martin ^a  

^a UNIVERSITY OF CONCEPCIÓN   (Chile)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATIN ORGANIZATION; CHROMATIN REMODELING; CHROMATIN REMODELING COMPLEX; CHROMATIN STRUCTURE; ELEVATED LEVEL; ENZYMATIC ACTIVITIES; HISTONE ACETYLATION; ISOFORM; MESENCHYMAL CELLS; NUCLEASE HYPERSENSITIVITY; OSTEOBLASTIC CELLS; PROMOTER REGION; REGULATORY ELEMENTS; RNA POLYMERASE II; SKELETAL DEVELOPMENT; STRUCTURAL COMPONENT; SWI/SNF; TRANSCRIPTIONAL ACTIVITY; TRANSCRIPTIONAL CO-ACTIVATORS;

ACETYLATION; BONE; CHROMOSOMES; NUCLEIC ACIDS; RNA; TRANSCRIPTION FACTORS;

TRANSCRIPTION;

BONE MORPHOGENETIC PROTEIN 2; CHOLECYSTOKININ OCTAPEPTIDE[28,31 N METHYLNORLEUCINE]; DEOXYRIBONUCLEASE; HISTONE; NUCLEASE; PROTEIN SWI; RNA POLYMERASE II; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SNF;

ANIMAL CELL; ARTICLE; CHROMATIN STRUCTURE; ENZYME ACTIVITY; GENE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RAT;

ACETYLATION; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; CELL LINE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOMAL PROTEINS, NON-HISTONE; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DEOXYRIBONUCLEASES; GENE EXPRESSION REGULATION; HISTONES; MICE; OSTEOBLASTS; PROMOTER REGIONS, GENETIC; PROTEIN ISOFORMS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 68049109194     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9004792     Document Type: Article

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