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Volumn 34, Issue 4, 2013, Pages 2093-2098

MicroRNAs in osteosarcoma: Diagnostic and therapeutic aspects

Author keywords

Diagnostic tool; MicroRNAs; Notch signaling pathway; Osteosarcoma; PI3K Akt signaling pathway; Therapeutic approach

Indexed keywords

MICRORNA; MICRORNA 1; MICRORNA 125B; MICRORNA 133B; MICRORNA 143; MICRORNA 15A; MICRORNA 16; MICRORNA 34A; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; STAT3 PROTEIN; UNCLASSIFIED DRUG;

EID: 84881472377     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-0940-7     Document Type: Review
Times cited : (142)

References (44)
  • 1
    • 77953669219 scopus 로고    scopus 로고
    • The epidemiology of osteosarcoma
    • 20213383 10.1007/978-1-4419-0284-9-1
    • Ottaviani G, Jaffe N. The epidemiology of osteosarcoma. Cancer Treat Res. 2009;152:3-13.
    • (2009) Cancer Treat Res , vol.152 , pp. 3-13
    • Ottaviani, G.1    Jaffe, N.2
  • 2
    • 77949332852 scopus 로고    scopus 로고
    • Osteosarcoma of medial cuniform bone
    • 20067146
    • Admassi D. Osteosarcoma of medial cuniform bone. Ethiop Med J. 2009;47:305-8.
    • (2009) Ethiop Med J , vol.47 , pp. 305-308
    • Admassi, D.1
  • 3
    • 63449118087 scopus 로고    scopus 로고
    • Osteosarcoma incidence and survival rates from 1973 to 2004: Data from the Surveillance, Epidemiology, and End Results Program
    • 19197972 10.1002/cncr.24121
    • Mirabello L, Troisi RJ, Savage SA. Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer. 2009;115:1531-43.
    • (2009) Cancer , vol.115 , pp. 1531-1543
    • Mirabello, L.1    Troisi, R.J.2    Savage, S.A.3
  • 4
    • 84858623789 scopus 로고    scopus 로고
    • A review of the association between osteosarcoma metastasis and protein translation
    • 22297074 10.1016/j.jcpa.2011.12.007 1:STN:280:DC%2BC38vhslCqug%3D%3D
    • Osborne TS, Khanna C. A review of the association between osteosarcoma metastasis and protein translation. J Comp Pathol. 2012;146:132-42.
    • (2012) J Comp Pathol , vol.146 , pp. 132-142
    • Osborne, T.S.1    Khanna, C.2
  • 5
    • 84862281808 scopus 로고    scopus 로고
    • The genetics of osteosarcoma
    • 22685381 10.1155/2012/627254
    • Martin JW, Squire JA, Zielenska M. The genetics of osteosarcoma. Sarcoma. 2012;2012:627254.
    • (2012) Sarcoma , vol.2012 , pp. 627254
    • Martin, J.W.1    Squire, J.A.2    Zielenska, M.3
  • 6
    • 62449159552 scopus 로고    scopus 로고
    • Molecular pathology of sarcomas
    • 19149759 10.2174/157488709787047585 1:CAS:528:DC%2BD1MXltlShu7g%3D
    • Osuna D, de Alava E. Molecular pathology of sarcomas. Rev Recent Clin Trials. 2009;4:12-26.
    • (2009) Rev Recent Clin Trials , vol.4 , pp. 12-26
    • Osuna, D.1    De Alava, E.2
  • 9
    • 54049089246 scopus 로고    scopus 로고
    • Current status and perspectives regarding the treatment of osteo-sarcoma: Chemotherapy
    • 18782081 10.2174/157488708785700267 1:CAS:528:DC%2BD1cXhtFSltbbP
    • Sakamoto A, Iwamoto Y. Current status and perspectives regarding the treatment of osteo-sarcoma: chemotherapy. Rev Recent Clin Trials. 2008;3:228-31.
    • (2008) Rev Recent Clin Trials , vol.3 , pp. 228-231
    • Sakamoto, A.1    Iwamoto, Y.2
  • 11
    • 0035033404 scopus 로고    scopus 로고
    • Current treatment of osteosarcoma
    • 11338887 10.1081/CNV-100102557 1:STN:280:DC%2BD3M3mt1Oguw%3D%3D
    • Ferguson WS, Goorin AM. Current treatment of osteosarcoma. Cancer Invest. 2001;19:292-315.
    • (2001) Cancer Invest , vol.19 , pp. 292-315
    • Ferguson, W.S.1    Goorin, A.M.2
  • 13
    • 37549010761 scopus 로고    scopus 로고
    • MicroRNA: Implications for cancer
    • 18040713 10.1007/s00428-007-0532-2 1:CAS:528:DC%2BD2sXhsVKkurjN
    • Sassen S, Miska EA, Caldas C. MicroRNA: implications for cancer. Virchows Arch. 2008;452:1-10.
    • (2008) Virchows Arch , vol.452 , pp. 1-10
    • Sassen, S.1    Miska, E.A.2    Caldas, C.3
  • 14
    • 0036847540 scopus 로고    scopus 로고
    • Ribonuclease activity and RNA binding of recombinant human dicer
    • 12411504 10.1093/emboj/cdf578 1:CAS:528:DC%2BD38XosVSrtLk%3D
    • Provost P, Dishart D, Doucet J, Frendewey D, Samuelsson B, Rådmark O. Ribonuclease activity and RNA binding of recombinant human dicer. EMBO J. 2002;21:5864-74.
    • (2002) EMBO J , vol.21 , pp. 5864-5874
    • Provost, P.1    Dishart, D.2    Doucet, J.3    Frendewey, D.4    Samuelsson, B.5    Rådmark, O.6
  • 16
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • 14567918 10.1016/S0092-8674(03)00801-8 1:CAS:528:DC%2BD3sXosFCqsLs%3D
    • Khvorova A, Reynolds A, Jayasena SD. Functional siRNAs and miRNAs exhibit strand bias. Cell. 2003;115:209-16.
    • (2003) Cell , vol.115 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 17
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • 15372072 10.1038/sj.emboj.7600385 1:CAS:528:DC%2BD2cXotlCrsrs%3D
    • Lee Y, Kim M, Han J, Yeom KH, Lee S, Baek SH, et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 2004;23:4051-60.
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.H.4    Lee, S.5    Baek, S.H.6    Kim, V.N.7
  • 18
    • 58149235625 scopus 로고    scopus 로고
    • MicroRNAs in embryonic stem cells
    • 18821562 10.1002/jcp.21607 1:CAS:528:DC%2BD1MXns1Sntw%3D%3D
    • Wang Y, Keys DN, Au-Young JK, Chen C. MicroRNAs in embryonic stem cells. J Cell Physiol. 2009;218:251-5.
    • (2009) J Cell Physiol , vol.218 , pp. 251-255
    • Wang, Y.1    Keys, D.N.2    Au-Young, J.K.3    Chen, C.4
  • 20
    • 84870915144 scopus 로고    scopus 로고
    • MicroRNAs in chronic lymphocytic leukemia: From causality to associations and back
    • 23216588 10.1586/ehm.12.54 1:CAS:528:DC%2BC38Xhsl2ls7zL
    • Mraz M, Pospisilova S. MicroRNAs in chronic lymphocytic leukemia: from causality to associations and back. Expert Rev Hematol. 2012;5:579-81.
    • (2012) Expert Rev Hematol , vol.5 , pp. 579-581
    • Mraz, M.1    Pospisilova, S.2
  • 21
    • 70350440048 scopus 로고    scopus 로고
    • Cloning and identification of microRNA from human osteosarcoma cell line SOSP-9607
    • 17562257 1:CAS:528:DC%2BD1cXovFKis7k%3D
    • Gao J, Yang TT, Qiu XC, Yu B, Han JW, Fan QY, et al. Cloning and identification of microRNA from human osteosarcoma cell line SOSP-9607. Ai Zheng. 2007;26:561-5.
    • (2007) Ai Zheng , vol.26 , pp. 561-565
    • Gao, J.1    Yang, T.T.2    Qiu, X.C.3    Yu, B.4    Han, J.W.5    Fan, Q.Y.6    Ma, B.A.7
  • 22
  • 23
    • 84880326050 scopus 로고    scopus 로고
    • MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma
    • doi: 10.1016/j.humpath.2013.01.016
    • Won KY, Kim YW, Kim HS, Lee SK, Jung WW, Park YK. MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma. Hum Pathol. 2013. doi: 10.1016/j.humpath.2013.01.016
    • (2013) Hum Pathol.
    • Won, K.Y.1    Kim, Y.W.2    Kim, H.S.3    Lee, S.K.4    Jung, W.W.5    Park, Y.K.6
  • 24
    • 84866056904 scopus 로고    scopus 로고
    • Changes in microRNA expression in the MG-63 osteosarcoma cell line compared with osteoblasts
    • 23162647
    • Hu H, Zhang Y, Cai XH, Huang JF, Cai L. Changes in microRNA expression in the MG-63 osteosarcoma cell line compared with osteoblasts. Oncol Lett. 2012;4:1037-42.
    • (2012) Oncol Lett , vol.4 , pp. 1037-1042
    • Hu, H.1    Zhang, Y.2    Cai, X.H.3    Huang, J.F.4    Cai, L.5
  • 28
    • 80051587553 scopus 로고    scopus 로고
    • MicroRNA-199a-3p is downregulated in human osteosarcoma and regulates cell proliferation and migration
    • 21666078 10.1158/1535-7163.MCT-11-0096 1:CAS:528:DC%2BC3MXhtFSqtLnP
    • Duan Z, Choy E, Harmon D, Liu X, Susa M, Mankin H, et al. MicroRNA-199a-3p is downregulated in human osteosarcoma and regulates cell proliferation and migration. Mol Cancer Ther. 2011;10:1337-45.
    • (2011) Mol Cancer Ther , vol.10 , pp. 1337-1345
    • Duan, Z.1    Choy, E.2    Harmon, D.3    Liu, X.4    Susa, M.5    Mankin, H.6    Hornicek, F.7
  • 29
    • 84873970191 scopus 로고    scopus 로고
    • Prognostic evaluation of microRNA-210 expression in pediatric osteosarcoma
    • 23430441 10.1007/s12032-013-0499-6
    • Cai H, Lin L, Cai H, Tang M, Wang Z. Prognostic evaluation of microRNA-210 expression in pediatric osteosarcoma. Med Oncol. 2013;30:499.
    • (2013) Med Oncol , vol.30 , pp. 499
    • Cai, H.1    Lin, L.2    Cai, H.3    Tang, M.4    Wang, Z.5
  • 30
    • 0033551070 scopus 로고    scopus 로고
    • New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
    • 10200246 10.1073/pnas.96.8.4240 1:CAS:528:DyaK1MXjs1ymtbg%3D
    • Cantley LC, Neel BG. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci U S A. 1999;96:4240-5.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 4240-4245
    • Cantley, L.C.1    Neel, B.G.2
  • 31
    • 58149215802 scopus 로고    scopus 로고
    • MiR-29 miRNAs activate p53 by targeting p85 alpha and CDC42
    • 19079265 10.1038/nsmb.1533 1:CAS:528:DC%2BD1cXhsV2hsrvF
    • Park SY, Lee JH, Ha M, Nam JW, Kim VN. miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42. Nat Struct Mol Biol. 2009;16:23-9.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 23-29
    • Park, S.Y.1    Lee, J.H.2    Ha, M.3    Nam, J.W.4    Kim, V.N.5
  • 32
    • 79960673180 scopus 로고    scopus 로고
    • Analysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma
    • 10.1016/j.cancergen.2010.12.012 1:CAS:528:DC%2BC3MXktFKlsrk%3D
    • Maire G, Martin JW, Yoshimoto M, Chilton-MacNeill S, Zielenska M, Squire JA. Analysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma. Cancer Gene. 2011;204:138-46.
    • (2011) Cancer Gene , vol.204 , pp. 138-146
    • Maire, G.1    Martin, J.W.2    Yoshimoto, M.3    Chilton-Macneill, S.4    Zielenska, M.5    Squire, J.A.6
  • 34
    • 84861090747 scopus 로고    scopus 로고
    • MicroRNA involvement in osteosarcoma
    • 22550419 10.1155/2012/359739
    • Kobayashi E, Hornicek FJ, Duan Z. MicroRNA involvement in osteosarcoma. Sarcoma. 2012;2012:359739.
    • (2012) Sarcoma , vol.2012 , pp. 359739
    • Kobayashi, E.1    Hornicek, F.J.2    Duan, Z.3
  • 37
    • 84876043424 scopus 로고    scopus 로고
    • MicroRNA-34a inhibits human osteosarcoma proliferation by downregulating ether à go-go 1 expression
    • 23569431 10.7150/ijms.5528 1:CAS:528:DC%2BC3sXnsFKgu7Y%3D
    • Wu X, Zhong D, Gao Q, Zhai W, Ding Z, Wu J. MicroRNA-34a inhibits human osteosarcoma proliferation by downregulating ether à go-go 1 expression. Int J Med Sci. 2013;10:676-82.
    • (2013) Int J Med Sci , vol.10 , pp. 676-682
    • Wu, X.1    Zhong, D.2    Gao, Q.3    Zhai, W.4    Ding, Z.5    Wu, J.6
  • 38
    • 84858632494 scopus 로고    scopus 로고
    • MicroRNA-34a inhibits the proliferation and metastasis of osteosarcoma cells both in vitro and in vivo
    • 22457788 10.1371/journal.pone.0033778 1:CAS:528:DC%2BC38XltVymsrc%3D
    • Yan K, Gao J, Yang T, Ma Q, Qiu X, Fan Q, et al. MicroRNA-34a inhibits the proliferation and metastasis of osteosarcoma cells both in vitro and in vivo. PLoS One. 2012;7:e33778.
    • (2012) PLoS One , vol.7 , pp. 33778
    • Yan, K.1    Gao, J.2    Yang, T.3    Ma, Q.4    Qiu, X.5    Fan, Q.6    Ma, B.7
  • 39
    • 83055163471 scopus 로고    scopus 로고
    • MiR-125b suppresses the proliferation and migration of osteosarcoma cells through down-regulation of STAT3
    • 22093834 10.1016/j.bbrc.2011.10.117 1:CAS:528:DC%2BC3MXhs1Sgsr%2FK
    • Liu LH, Li H, Li JP, Zhong H, Zhang HC, Chen J, et al. miR-125b suppresses the proliferation and migration of osteosarcoma cells through down-regulation of STAT3. Biochem Biophys Res Commun. 2011;416:31-8.
    • (2011) Biochem Biophys Res Commun , vol.416 , pp. 31-38
    • Liu, L.H.1    Li, H.2    Li, J.P.3    Zhong, H.4    Zhang, H.C.5    Chen, J.6    Xiao, T.7
  • 40
    • 78149320174 scopus 로고    scopus 로고
    • MicroRNA-143, down-regulated in osteosarcoma, promotes apoptosis and suppresses tumorigenicity by targeting Bcl-2
    • 20878132 1:CAS:528:DC%2BC3cXhsVegsbjI
    • Zhang H, Cai X, Wang Y, Tang H, Tong D, Ji F. microRNA-143, down-regulated in osteosarcoma, promotes apoptosis and suppresses tumorigenicity by targeting Bcl-2. Oncol Rep. 2010;24:1363-9.
    • (2010) Oncol Rep , vol.24 , pp. 1363-1369
    • Zhang, H.1    Cai, X.2    Wang, Y.3    Tang, H.4    Tong, D.5    Ji, F.6
  • 41
    • 84860445335 scopus 로고    scopus 로고
    • MicroRNA-145 targets vascular endothelial growth factor and inhibits invasion and metastasis of osteosarcoma cells
    • 10.1093/abbs/gms019 1:CAS:528:DC%2BC38XmsFars7o%3D
    • Fan L, Wu Q, Xing X, Wei Y, Shao Z. MicroRNA-145 targets vascular endothelial growth factor and inhibits invasion and metastasis of osteosarcoma cells. Acta Biochim Biophys Sin (Shanghai). 2012;44:407-14.
    • (2012) Acta Biochim Biophys Sin (Shanghai) , vol.44 , pp. 407-414
    • Fan, L.1    Wu, Q.2    Xing, X.3    Wei, Y.4    Shao, Z.5
  • 42
    • 84866616313 scopus 로고    scopus 로고
    • MiR-183 inhibits the metastasis of osteosarcoma via downregulation of the expression of Ezrin in F5M2 cells
    • 22922800 1:CAS:528:DC%2BC38Xhs1KrtbnF
    • Zhao H, Guo M, Zhao G, Ma Q, Ma B, Qiu X, et al. miR-183 inhibits the metastasis of osteosarcoma via downregulation of the expression of Ezrin in F5M2 cells. Int J Mol Med. 2012;30:1013-20.
    • (2012) Int J Mol Med , vol.30 , pp. 1013-1020
    • Zhao, H.1    Guo, M.2    Zhao, G.3    Ma, Q.4    Ma, B.5    Qiu, X.6    Fan, Q.7
  • 43
    • 84878372074 scopus 로고    scopus 로고
    • MiR-223/Ect2/p21 signaling regulates osteosarcoma cell cycle progression and proliferation
    • doi: 10.1016/j.biopha.2013.03.013
    • Xu J, Yao Q, Hou Y, Xu M, Liu S, Yang L, Zhang L, Xu H. MiR-223/Ect2/p21 signaling regulates osteosarcoma cell cycle progression and proliferation. Biomed Pharmacother. 2013. doi: 10.1016/j.biopha.2013.03.013
    • (2013) Biomed Pharmacother.
    • Xu, J.1    Yao, Q.2    Hou, Y.3    Xu, M.4    Liu, S.5    Yang, L.6    Zhang, L.7    Xu, H.8
  • 44
    • 77956652041 scopus 로고    scopus 로고
    • MiRNAs as biomarkers and therapeutic targets in cancer
    • 20541466 10.1016/j.coph.2010.05.010 1:CAS:528:DC%2BC3cXhtFygurbE
    • Heneghan HM, Miller N, Kerin MJ. MiRNAs as biomarkers and therapeutic targets in cancer. Curr Opin Pharmacol. 2010;10:543-50.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 543-550
    • Heneghan, H.M.1    Miller, N.2    Kerin, M.J.3


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