Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPαlpha promoter methylation

Cell Death and Disease

Volumn 4, Issue 10, 2013, Pages

  Li, J ^a   Zhang, N ^a   Huang, X ^a   Xu, J ^b   Fernandes, J C ^c   Dai, K ^a   Zhang, X ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

Author keywords

BMSC differentiation; C EBP lpha; DNA methylation; Osteoporosis; Wnt beta catenin

Indexed keywords

BETA CATENIN; BONE MORPHOGENETIC PROTEIN 2; CCAAT ENHANCER BINDING PROTEIN ALPHA; DEXAMETHASONE; WNT PROTEIN;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL ASSAY; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA METHYLATION; IN VITRO STUDY; IN VIVO STUDY; MALE; METHYLATION; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOPOROSIS; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA PURIFICATION; SIGNAL TRANSDUCTION; STROMA CELL; UPREGULATION; WESTERN BLOTTING;

ADIPOCYTES; ADIPOGENESIS; ADIPOSITY; ANIMALS; BONE DENSITY; BONE MORPHOGENETIC PROTEIN 2; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; DEXAMETHASONE; DNA METHYLATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; LITHIUM CHLORIDE; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; OSTEOBLASTS; OSTEOGENESIS; OSTEOPOROSIS; PROMOTER REGIONS, GENETIC; WNT SIGNALING PATHWAY;

EID: 84887490574     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.348     Document Type: Article

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