NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer

Nature Reviews Urology

Volumn 11, Issue 9, 2014, Pages 499-507

  Flores, Angela N ^a   McDermott, Niamh ^b   Meunier, Armelle ^b   Marignol, Laure ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; GAMMA SECRETASE INHIBITOR; MONOCLONAL ANTIBODY; NATURAL PRODUCT; NOTCH RECEPTOR; NUCLEAR PROTEIN; NUMB PROTEIN; PROTEIN MDM2; PROTEIN P53; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; NERVE PROTEIN; NUMB PROTEIN, HUMAN;

ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ANGIOGENESIS; APOPTOSIS; CANCER STEM CELL; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CELL ADHESION; CELL DIFFERENTIATION; CELL FATE; CELL HYPOXIA; CELL PROLIFERATION; ENDOCYTOSIS; ENZYME INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; GLYCOSYLATION; HUMAN; HYDROXYLATION; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN ACETYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; UBIQUITINATION; MALE; PHYSIOLOGY; PROSTATE TUMOR;

CELL DIFFERENTIATION; HUMANS; MALE; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; PROSTATIC NEOPLASMS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84908086267     PISSN: 17594812     EISSN: 17594820     Source Type: Journal    
DOI: 10.1038/nrurol.2014.195     Document Type: Review

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