NVP-LDE-225 (Erismodegib) inhibits epithelial-mesenchymal transition and human prostate cancer stem cell growth in NOD/SCID IL2Rγ null mice by regulating Bmi-1 and microRNA-128

Oncogenesis

Volumn 2, Issue , 2013, Pages

  Nanta, R ^a   Kumar, D ^a   Meeker, D ^a   Rodova, M ^a   Van Veldhuizen, P J ^a   Shankar, S ^a   Srivastava, R K ^a  

^a UNIVERSITY OF KANSAS CANCER CENTER   (United States)

Author keywords

Cell survival; Gli transcription factors; NVP LDE 225; Prostate cancer stem cells; Sonic hedgehog signaling

Indexed keywords

BMI1 PROTEIN; MICRORNA; MICRORNA 128; PROTEIN BCL 2; SONIDEGIB; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER STEM CELL; CELL VIABILITY; DRUG EFFICACY; EPITHELIAL MESENCHYMAL TRANSITION; GENE CONTROL; GENE EXPRESSION; HUMAN; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; RECEPTOR UPREGULATION; TUMOR SPHEROID;

EID: 84880168463     PISSN: None     EISSN: 21579024     Source Type: Journal    
DOI: 10.1038/oncsis.2013.5     Document Type: Article

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