-
1
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
Adams. J., V.J. Palombella, E.A. Sausville, J. Johnson, A. Destree, D.D. Lazarus, J. Maas, C.S. Pien, S. Prakash, and P.J. Elliott. 1999. Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res. 59:2615-2622.
-
(1999)
Cancer Res.
, vol.59
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
Sausville, E.A.3
Johnson, J.4
Destree, A.5
Lazarus, D.D.6
Maas, J.7
Pien, C.S.8
Prakash, S.9
Elliott, P.J.10
-
2
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas, S., M.D. Rand, and R.J. Lake. 1999. Notch signaling: cell fate control and signal integration in development. Science. 284:770-776.
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
3
-
-
0030820930
-
Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2
-
Capobianco, A.J., P. Zagouras, C.M. Blaumueller, S. Artavanis-Tsakonas, and J.M. Bishop. 1997. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Mol. Cell Biol. 17:6265-6213.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 6265-16213
-
-
Capobianco, A.J.1
Zagouras, P.2
Blaumueller, C.M.3
Artavanis-Tsakonas, S.4
Bishop, J.M.5
-
4
-
-
0031962189
-
Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo
-
Chien, C.T., S. Wang, M. Rothenberg, L.Y. Jan, and Y.N. Jan. 1998. Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo. Mol. Cell. Biol. 18:598-607.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 598-607
-
-
Chien, C.T.1
Wang, S.2
Rothenberg, M.3
Jan, L.Y.4
Jan, Y.N.5
-
5
-
-
0025856717
-
TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
-
Ellisen, L.W., J, Bird, D.C. West, A.L. Soreng, T.C. Reynolds, S.D. Smith, and J. Sklar. 1991. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell. 66:649-661.
-
(1991)
Cell
, vol.66
, pp. 649-661
-
-
Ellisen, L.W.1
Bird, J.2
West, D.C.3
Soreng, A.L.4
Reynolds, T.C.5
Smith, S.D.6
Sklar, J.7
-
6
-
-
0029909203
-
The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage
-
Frise, E., J.A. Knoblich, S. Younger-Shepherd, L.Y. Jan, and Y.N. Jan. 1996. The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage. Proc. Natl. Acad. Sci. USA. 93:11925-11932.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11925-11932
-
-
Frise, E.1
Knoblich, J.A.2
Younger-Shepherd, S.3
Jan, L.Y.4
Jan, Y.N.5
-
7
-
-
0029871104
-
Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis
-
Gallahan, D., C. Jhappan, G. Robinson, L. Hennighausen, R. Sharp, E. Kordon, R. Callahan, G. Merlino, and G.H. Smith. 1996. Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis. Cancer Res. 56:1775-1785.
-
(1996)
Cancer Res.
, vol.56
, pp. 1775-1785
-
-
Gallahan, D.1
Jhappan, C.2
Robinson, G.3
Hennighausen, L.4
Sharp, R.5
Kordon, E.6
Callahan, R.7
Merlino, G.8
Smith, G.H.9
-
8
-
-
0030199973
-
Control of daughter cell fates during asymmetric division: Interaction of Numb and Notch
-
Guo, M., L.Y. Jan, and Y.N. Jan. 1996. Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron. 17:27-41.
-
(1996)
Neuron
, vol.17
, pp. 27-41
-
-
Guo, M.1
Jan, L.Y.2
Jan, Y.N.3
-
9
-
-
0345178412
-
Serum-free growth of human mammary epithelial cells: Rapid clonal growth in defined medium and extended serial passage with pituitary extract
-
Hammond, S.L., R.G. Ham, and M.R. Stampfer. 1984. Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract. Proc. Natl. Acad. Sci. USA. 81:5435-5439.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 5435-5439
-
-
Hammond, S.L.1
Ham, R.G.2
Stampfer, M.R.3
-
10
-
-
0031785161
-
Delta-1 activation of notch-1 signaling results in HES-1 transactivation
-
Jarriault, S., O. Le Bail, E. Hirsinger, O. Pourquie, F. Logeat, C.F. Strong, C. Brou, N.G. Seidah, and A. Israel. 1998. Delta-1 activation of notch-1 signaling results in HES-1 transactivation. Mol. Cell. Biol. 18:7423-7431.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7423-7431
-
-
Jarriault, S.1
Le Bail, O.2
Hirsinger, E.3
Pourquie, O.4
Logeat, F.5
Strong, C.F.6
Brou, C.7
Seidah, N.G.8
Israel, A.9
-
11
-
-
0026517312
-
Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands
-
Jhappan, C., D. Gallahan, C. Stahle, E. Chu, G.H. Smith, G. Merlino, and R. Callahan. 1992. Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands. Genes Dev. 6:345-355.
-
(1992)
Genes Dev.
, vol.6
, pp. 345-355
-
-
Jhappan, C.1
Gallahan, D.2
Stahle, C.3
Chu, E.4
Smith, G.H.5
Merlino, G.6
Callahan, R.7
-
12
-
-
0031835660
-
The Mdm2 oncoprotein interacts with the cell fate regulator Numb
-
Juven-Gershon, T., O. Shifman, T. Unger, A. Elkeles, Y. Haupt, and M. Oren. 1998. The Mdm2 oncoprotein interacts with the cell fate regulator Numb. Mol. Cell. Biol. 18:3974-3982.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3974-3982
-
-
Juven-Gershon, T.1
Shifman, O.2
Unger, T.3
Elkeles, A.4
Haupt, Y.5
Oren, M.6
-
13
-
-
0034671686
-
Notch signaling: From the outside in
-
Mumm, J.S., and R. Kopan. 2000. Notch signaling: from the outside in. Dev. Biol. 228:151-165.
-
(2000)
Dev. Biol.
, vol.228
, pp. 151-165
-
-
Mumm, J.S.1
Kopan, R.2
-
14
-
-
0037080811
-
LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation
-
Nie, J., M.A. McGill, M. Dermer, S.E. Dho, C.D. Wolting, and C.J. McGlade. 2002. LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation. EMBO J. 21:93-102.
-
(2002)
EMBO J.
, vol.21
, pp. 93-102
-
-
Nie, J.1
McGill, M.A.2
Dermer, M.3
Dho, S.E.4
Wolting, C.D.5
McGlade, C.J.6
-
15
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart, CM. 2001. Mechanisms underlying ubiquitination. Arum. Rev. Biochem. 70:503-533.
-
(2001)
Arum. Rev. Biochem.
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
16
-
-
0027947609
-
Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
-
Rhyu, M.S., L.Y. Jan, and Y.N. Jan. 1994. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell. 76:477-491.
-
(1994)
Cell
, vol.76
, pp. 477-491
-
-
Rhyu, M.S.1
Jan, L.Y.2
Jan, Y.N.3
-
17
-
-
0026554890
-
Mouse mammary tumor gene int-3: A member of the notch gene family transforms mammary epithelial cells
-
Robbins, J., B.J. Blondel, D. Gallahan, and R. Callahan. 1992. Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells. J. Virol. 66:2594-2599.
-
(1992)
J. Virol.
, vol.66
, pp. 2594-2599
-
-
Robbins, J.1
Blondel, B.J.2
Gallahan, D.3
Callahan, R.4
-
18
-
-
0034638843
-
Numb is an endocytic protein
-
Santolini, E., C. Puri, A.E. Salcini, M.C. Gagliani, P.G. Pelicci, C. Tacchetti, and P.P. Di Fiore. 2000. Numb is an endocytic protein. J. Cell Biol. 151:1345-1352.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1345-1352
-
-
Santolini, E.1
Puri, C.2
Salcini, A.E.3
Gagliani, M.C.4
Pelicci, P.G.5
Tacchetti, C.6
Di Fiore, P.P.7
-
19
-
-
0027083415
-
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split
-
Sasai, Y., R. Kageyama, Y. Tagawa, R. Shigemoto, and S. Nakanishi. 1992. Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev. 6:2620-2634.
-
(1992)
Genes Dev.
, vol.6
, pp. 2620-2634
-
-
Sasai, Y.1
Kageyama, R.2
Tagawa, Y.3
Shigemoto, R.4
Nakanishi, S.5
-
20
-
-
0032574993
-
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
-
Schroeter, E.H., J.A. Kisslinger, and R. Kopan. 1998. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature. 393:382-386.
-
(1998)
Nature
, vol.393
, pp. 382-386
-
-
Schroeter, E.H.1
Kisslinger, J.A.2
Kopan, R.3
-
21
-
-
0031739920
-
Short-term primary culture of epithelial cells derived from human breast tumours
-
Speirs, V., A.R. Green, D.S. Walton, M.J. Kerin, J.N. Fox, P.J. Carleton, S.B. Desai, and S.L. Atkin. 1998. Short-term primary culture of epithelial cells derived from human breast tumours. Br. J. Cancer. 78:1421-1429.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1421-1429
-
-
Speirs, V.1
Green, A.R.2
Walton, D.S.3
Kerin, M.J.4
Fox, J.N.5
Carleton, P.J.6
Desai, S.B.7
Atkin, S.L.8
-
22
-
-
0033639117
-
Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins
-
Struhl, G., and A. Adachi. 2000. Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins. Mol. Cell. 6:625-636.
-
(2000)
Mol. Cell.
, vol.6
, pp. 625-636
-
-
Struhl, G.1
Adachi, A.2
-
23
-
-
0035909894
-
Siah-1 binds and regulates the function of Numb
-
Susini, L., B.J. Passer, N. Amzallag-Elbaz, T. Juven-Gershon, S. Prieur, N. Privat, M. Tuynder, M.C. Gendron, A. Israel, R. Amson, et al. 2001. Siah-1 binds and regulates the function of Numb. Proc. Natl. Acad. Sci. USA. 98:15067-15072.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 15067-15072
-
-
Susini, L.1
Passer, B.J.2
Amzallag-Elbaz, N.3
Juven-Gershon, T.4
Prieur, S.5
Privat, N.6
Tuynder, M.7
Gendron, M.C.8
Israel, A.9
Amson, R.10
-
24
-
-
0036734148
-
Activation of Notch-l signaling maintains the neoplastic phenotype in human Rastransformed cells
-
Weijzen, S., P. Rizzo, M. Braid, R. Vaishnav, S.M. Jonkheer, A. Zlobin, B.A. Osborne, S. Gottipati, J.C. Aster, W.C. Hahn, et al. 2002. Activation of Notch-l signaling maintains the neoplastic phenotype in human Rastransformed cells. Nat. Med. 8:979-986.
-
(2002)
Nat. Med.
, vol.8
, pp. 979-986
-
-
Weijzen, S.1
Rizzo, P.2
Braid, M.3
Vaishnav, R.4
Jonkheer, S.M.5
Zlobin, A.6
Osborne, B.A.7
Gottipati, S.8
Aster, J.C.9
Hahn, W.C.10
-
25
-
-
0037218811
-
Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling
-
Weng, A.P., Y. Nam, M.S. Wolfe, W.S. Pear, I.D. Griffin, S.C. Blacklow, and J.C. Aster. 2003. Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling. Mol. Cell. Biol. 23:655-664.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 655-664
-
-
Weng, A.P.1
Nam, Y.2
Wolfe, M.S.3
Pear, W.S.4
Griffin, I.D.5
Blacklow, S.C.6
Aster, J.C.7
-
26
-
-
0030200217
-
Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis
-
Zhong, W., J.N. Feder, M.M. Jiang, L.Y. Jan, and Y.N. Jan. 1996. Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis. Neuron. 17:43-53.
-
(1996)
Neuron
, vol.17
, pp. 43-53
-
-
Zhong, W.1
Feder, J.N.2
Jiang, M.M.3
Jan, L.Y.4
Jan, Y.N.5
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