Kuzbanian-mediated cleavage of Drosophila Notch

Genes and Development

Volumn 16, Issue 2, 2002, Pages 209-221

  Lieber, Toby ^a   Kidd, Simon ^a   Young, Michael W ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Drosophila; Kuzbanian; Notch; Processing

Indexed keywords

DNA; METALLOPROTEINASE; NOTCH RECEPTOR; RNA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ARTICLE; DROSOPHILA; IMMUNOPRECIPITATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; CELL NUCLEUS; DISINTEGRINS; DNA PRIMERS; DROSOPHILA; DROSOPHILA PROTEINS; HYDROLYSIS; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; PHENOTYPE; PRECIPITIN TESTS; RECEPTORS, NOTCH; RNA;

EID: 0037080699     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.942302     Document Type: Article

References (36)

1. Notch signaling: Cell fate control and signal integration in development
2. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane
3. Cloning and characterization of the Drosophila presenilin homologue
4. The Abruptex mutations of Notch disrupt the establishment of proneural clusters in Drosophila
5. A novel proteolytic cleavage involved in Notch signaling: The role of the disintegrin-metalloprotease TACE
6. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
7. A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
8. Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila
9. FlyBase - A Drosophila database
10. LIN-12/Notch signaling: Lessons from worms and flies
11. Regulated cleavage of a contact-mediated axon repellent
12. Delta-1 activation of Notch-1 signaling results in HES-1 transactivation
13. Structure and distribution of the Notch protein in developing Drosophila
14. Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos
15. Structural requirements for Notch signalling with delta and serrate during the development and patterning of the wing disc of Drosophila
16. Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos
17. Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei
18. The Notch1 receptor is cleaved constitutively by a furin-like convertase
19. Delta signaling from the germ line controls the proliferation and differentiation of the somatic follicle cells during Drosophila oogenesis
20. Notch signaling: From the outside in
21. A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1
22. Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis
23. The ADAM gene family: Surface proteins with adhesion and protease activity
24. Processing of the Notch ligand Delta by the metalloprotease Kuzbanian
25. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor
26. Identification and immunochemical analysis of biologically active Drosophila P element transposase
27. KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis
28. Uncoupling cadherin-based adhesion from wingless signalling in Drosophila
29. Metalloprotease-disintegrins: Modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding
30. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
31. The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs
32. Nuclear access and action of Notch in vivo
33. Presenilin is required for activity and nuclear access of Notch in Drosophila
34. SUP-17, a Caenorhabditis elegans ADAM protein related to Drosophila Kuzbanian, and its role in LIN-12/NOTCH signalling
35. Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila
36. Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants