-
1
-
-
0036174513
-
Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia
-
S.A. Abdulkadir, J.A. Magee, T.J. Peters, Z. Kaleem, C.K. Naughton, P.A. Humphrey, and J. Milbrandt Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia Mol. Cell. Biol. 22 2002 1495 1503
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1495-1503
-
-
Abdulkadir, S.A.1
Magee, J.A.2
Peters, T.J.3
Kaleem, Z.4
Naughton, C.K.5
Humphrey, P.A.6
Milbrandt, J.7
-
2
-
-
0031670756
-
Specific transcription factors prognostic for prostate cancer progression
-
K. Aoyagi, I. Shima, M. Wang, Y. Hu, F.U. Garcia, and M.E. Stearns Specific transcription factors prognostic for prostate cancer progression Clin. Cancer Res. 4 1998 2153 2160
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 2153-2160
-
-
Aoyagi, K.1
Shima, I.2
Wang, M.3
Hu, Y.4
Garcia, F.U.5
Stearns, M.E.6
-
3
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
S. Artavanis-Tsakonas, M.D. Rand, and R.J. Lake Notch signaling: cell fate control and signal integration in development Science 284 1999 770 776
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
4
-
-
1542357306
-
Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis
-
D.M. Berman, N. Desai, X. Wang, S.S. Karhadkar, M. Reynon, C. Abate-Shen, P.A. Beachy, and M.M. Shen Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis Dev. Biol. 267 2004 387 398
-
(2004)
Dev. Biol.
, vol.267
, pp. 387-398
-
-
Berman, D.M.1
Desai, N.2
Wang, X.3
Karhadkar, S.S.4
Reynon, M.5
Abate-Shen, C.6
Beachy, P.A.7
Shen, M.M.8
-
6
-
-
0033561173
-
Roles for Nkx3.1 in prostate development and cancer
-
R. Bhatia-Gaur, A.A. Donjacour, P.J. Sciavolino, M. Kim, N. Desai, P. Young, C.R. Norton, T. Gridley, R.D. Cardiff, G.R. Cunha, C. Abate-Shen, and M.M. Shen Roles for Nkx3.1 in prostate development and cancer Genes Dev. 13 1999 966 977
-
(1999)
Genes Dev.
, vol.13
, pp. 966-977
-
-
Bhatia-Gaur, R.1
Donjacour, A.A.2
Sciavolino, P.J.3
Kim, M.4
Desai, N.5
Young, P.6
Norton, C.R.7
Gridley, T.8
Cardiff, R.D.9
Cunha, G.R.10
Abate-Shen, C.11
Shen, M.M.12
-
7
-
-
0029819186
-
Role of the basal cells in premalignant changes of the human prostate: A stem cell concept for the development of prostate cancer
-
H. Bonkhoff Role of the basal cells in premalignant changes of the human prostate: a stem cell concept for the development of prostate cancer Eur. Urol. 30 1996 201 205
-
(1996)
Eur. Urol.
, vol.30
, pp. 201-205
-
-
Bonkhoff, H.1
-
8
-
-
0036510745
-
Repression of activator protein-1-mediated transcriptional activation by the Notch-1 intracellular domain
-
J. Chu, S. Jeffries, J.E. Norton, A.J. Capobianco, and E.H. Bresnick Repression of activator protein-1-mediated transcriptional activation by the Notch-1 intracellular domain J. Biol. Chem. 277 2002 7587 7597
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7587-7597
-
-
Chu, J.1
Jeffries, S.2
Norton, J.E.3
Capobianco, A.J.4
Bresnick, E.H.5
-
9
-
-
17144365000
-
Induction of AP-1 activity by androgen activation of the androgen receptor in LNCaP human prostate carcinoma cells
-
D.R. Church, E. Lee, T.A. Thompson, H.S. Basu, M.O. Ripple, E.A. Ariazi, and G. Wilding Induction of AP-1 activity by androgen activation of the androgen receptor in LNCaP human prostate carcinoma cells Prostate 63 2005 155 168
-
(2005)
Prostate
, vol.63
, pp. 155-168
-
-
Church, D.R.1
Lee, E.2
Thompson, T.A.3
Basu, H.S.4
Ripple, M.O.5
Ariazi, E.A.6
Wilding, G.7
-
10
-
-
4344580888
-
Strategies for disease modification in Alzheimer's disease
-
M. Citron Strategies for disease modification in Alzheimer's disease Nat. Rev., Neurosci. 5 2004 677 685
-
(2004)
Nat. Rev., Neurosci.
, vol.5
, pp. 677-685
-
-
Citron, M.1
-
11
-
-
0028989016
-
Notch1 is required for the coordinate segmentation of somites
-
R.A. Conlon, A.G. Reaume, and J. Rossant Notch1 is required for the coordinate segmentation of somites Development 121 1995 1533 1545
-
(1995)
Development
, vol.121
, pp. 1533-1545
-
-
Conlon, R.A.1
Reaume, A.G.2
Rossant, J.3
-
12
-
-
0347519180
-
Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation
-
C. Dahlqvist, A. Blokzijl, G. Chapman, A. Falk, K. Dannaeus, C.F. Ibanez, and U. Lendahl Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation Development 130 2003 6089 6099
-
(2003)
Development
, vol.130
, pp. 6089-6099
-
-
Dahlqvist, C.1
Blokzijl, A.2
Chapman, G.3
Falk, A.4
Dannaeus, K.5
Ibanez, C.F.6
Lendahl, U.7
-
13
-
-
0033535504
-
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
-
B. De Strooper, W. Annaert, P. Cupers, P. Saftig, K. Craessaerts, J.S. Mumm, E.H. Schroeter, V. Schrijvers, M.S. Wolfe, W.J. Ray, A. Goate, and R. Kopan A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain Nature 398 1999 518 522
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.S.6
Schroeter, E.H.7
Schrijvers, V.8
Wolfe, M.S.9
Ray, W.J.10
Goate, A.11
Kopan, R.12
-
15
-
-
0042162919
-
FGF-10 plays an essential role in the growth of the fetal prostate
-
A.A. Donjacour, A.A. Thomson, and G.R. Cunha FGF-10 plays an essential role in the growth of the fetal prostate Dev. Biol. 261 2003 39 54
-
(2003)
Dev. Biol.
, vol.261
, pp. 39-54
-
-
Donjacour, A.A.1
Thomson, A.A.2
Cunha, G.R.3
-
16
-
-
0025856717
-
TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
-
L.W. Ellisen, J. Bird, D.C. West, A.L. Soreng, T.C. Reynolds, S.D. Smith, and J. Sklar TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms Cell 66 1991 649 661
-
(1991)
Cell
, vol.66
, pp. 649-661
-
-
Ellisen, L.W.1
Bird, J.2
West, D.C.3
Soreng, A.L.4
Reynolds, T.C.5
Smith, S.D.6
Sklar, J.7
-
17
-
-
0037022644
-
Activity-dependent isolation of the presenilin-gamma-secretase complex reveals nicastrin and a gamma substrate
-
W.P. Esler, W.T. Kimberly, B.L. Ostaszewski, W. Ye, T.S. Diehl, D.J. Selkoe, and M.S. Wolfe Activity-dependent isolation of the presenilin-gamma- secretase complex reveals nicastrin and a gamma substrate Proc. Natl. Acad. Sci. U. S. A. 99 2002 2720 2725
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 2720-2725
-
-
Esler, W.P.1
Kimberly, W.T.2
Ostaszewski, B.L.3
Ye, W.4
Diehl, T.S.5
Selkoe, D.J.6
Wolfe, M.S.7
-
18
-
-
0036727125
-
Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling
-
M.E. Fortini Gamma-secretase-mediated proteolysis in cell-surface- receptor signalling Nat. Rev., Mol. Cell Biol. 3 2002 673 684
-
(2002)
Nat. Rev., Mol. Cell Biol.
, vol.3
, pp. 673-684
-
-
Fortini, M.E.1
-
19
-
-
0344925869
-
Sonic hedgehog regulates prostatic growth and epithelial differentiation
-
S.H. Freestone, P. Marker, O.C. Grace, D.C. Tomlinson, G.R. Cunha, P. Harnden, and A.A. Thomson Sonic hedgehog regulates prostatic growth and epithelial differentiation Dev. Biol. 264 2003 352 362
-
(2003)
Dev. Biol.
, vol.264
, pp. 352-362
-
-
Freestone, S.H.1
Marker, P.2
Grace, O.C.3
Tomlinson, D.C.4
Cunha, G.R.5
Harnden, P.6
Thomson, A.A.7
-
20
-
-
0033610866
-
CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1
-
K. Fronsdal, N. Engedal, T. Slagsvold, and F. Saatcioglu CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1 J. Biol. Chem. 273 1998 31853 31859
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 31853-31859
-
-
Fronsdal, K.1
Engedal, N.2
Slagsvold, T.3
Saatcioglu, F.4
-
21
-
-
0023226698
-
A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17
-
D. Gallahan, C. Kozak, and R. Callahan A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17 J. Virol. 61 1987 218 220
-
(1987)
J. Virol.
, vol.61
, pp. 218-220
-
-
Gallahan, D.1
Kozak, C.2
Callahan, R.3
-
22
-
-
0029871104
-
Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis
-
D. Gallahan, C. Jhappan, G. Robinson, L. Hennighausen, R. Sharp, E. Kordon, R. Callahan, G. Merlino, and G.H. Smith Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis Cancer Res. 56 1996 1775 1785
-
(1996)
Cancer Res.
, vol.56
, pp. 1775-1785
-
-
Gallahan, D.1
Jhappan, C.2
Robinson, G.3
Hennighausen, L.4
Sharp, R.5
Kordon, E.6
Callahan, R.7
Merlino, G.8
Smith, G.H.9
-
23
-
-
0036023971
-
A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish
-
A. Geling, H. Steiner, M. Willem, L. Bally-Cuif, and C. Haass A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish EMBO Rep. 3 2002 688 694
-
(2002)
EMBO Rep.
, vol.3
, pp. 688-694
-
-
Geling, A.1
Steiner, H.2
Willem, M.3
Bally-Cuif, L.4
Haass, C.5
-
24
-
-
0027070519
-
The function of the neurogenic genes during epithelial development in the Drosophila embryo
-
A.Y. Hartenstein, A. Rugendorff, U. Tepass, and V. Hartenstein The function of the neurogenic genes during epithelial development in the Drosophila embryo Development 116 1992 1203 1220
-
(1992)
Development
, vol.116
, pp. 1203-1220
-
-
Hartenstein, A.Y.1
Rugendorff, A.2
Tepass, U.3
Hartenstein, V.4
-
25
-
-
0029885887
-
Normal development and carcinogenesis of the prostate. a unifying hypothesis
-
S.W. Hayward, G.R. Cunha, and R. Dahiya Normal development and carcinogenesis of the prostate. A unifying hypothesis Ann. N. Y. Acad. Sci. 784 1996 50 62
-
(1996)
Ann. N. Y. Acad. Sci.
, vol.784
, pp. 50-62
-
-
Hayward, S.W.1
Cunha, G.R.2
Dahiya, R.3
-
26
-
-
9744241715
-
Fibroblast growth factor 17 is over-expressed in human prostate cancer
-
R. Heer, D. Douglas, M.E. Mathers, C.N. Robson, and H.Y. Leung Fibroblast growth factor 17 is over-expressed in human prostate cancer J. Pathol. 204 2004 578 586
-
(2004)
J. Pathol.
, vol.204
, pp. 578-586
-
-
Heer, R.1
Douglas, D.2
Mathers, M.E.3
Robson, C.N.4
Leung, H.Y.5
-
27
-
-
11344265202
-
Epithelial stem cells in human prostate growth and disease
-
D.L. Hudson Epithelial stem cells in human prostate growth and disease Prostate Cancer Prostatic Dis. 7 2004 188 194
-
(2004)
Prostate Cancer Prostatic Dis.
, vol.7
, pp. 188-194
-
-
Hudson, D.L.1
-
28
-
-
0024832529
-
Etiology and disease process of benign prostatic hyperplasia
-
J.T. Isaacs, and D.S. Coffey Etiology and disease process of benign prostatic hyperplasia Prostate, Suppl. 2 1989 33 50
-
(1989)
Prostate, Suppl.
, vol.2
, pp. 33-50
-
-
Isaacs, J.T.1
Coffey, D.S.2
-
29
-
-
0037363922
-
HES and HERP families: Multiple effectors of the Notch signaling pathway
-
T. Iso, L. Kedes, and Y. Hamamori HES and HERP families: multiple effectors of the Notch signaling pathway J. Cell. Physiol. 194 2003 237 255
-
(2003)
J. Cell. Physiol.
, vol.194
, pp. 237-255
-
-
Iso, T.1
Kedes, L.2
Hamamori, Y.3
-
30
-
-
0026517312
-
Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands
-
C. Jhappan, D. Gallahan, C. Stahle, E. Chu, G.H. Smith, G. Merlino, and R. Callahan Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands Genes Dev. 6 1992 345 355
-
(1992)
Genes Dev.
, vol.6
, pp. 345-355
-
-
Jhappan, C.1
Gallahan, D.2
Stahle, C.3
Chu, E.4
Smith, G.H.5
Merlino, G.6
Callahan, R.7
-
31
-
-
6044243650
-
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
-
S.S. Karhadkar, G.S. Bova, N. Abdallah, S. Dhara, D. Gardner, A. Maitra, J.T. Isaacs, D.M. Berman, and P.A. Beachy Hedgehog signalling in prostate regeneration, neoplasia and metastasis Nature 431 2004 707 712
-
(2004)
Nature
, vol.431
, pp. 707-712
-
-
Karhadkar, S.S.1
Bova, G.S.2
Abdallah, N.3
Dhara, S.4
Gardner, D.5
Maitra, A.6
Isaacs, J.T.7
Berman, D.M.8
Beachy, P.A.9
-
32
-
-
0036605972
-
Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis
-
M.J. Kim, R. Bhatia-Gaur, W.A. Banach-Petrosky, N. Desai, Y. Wang, S.W. Hayward, G.R. Cunha, R.D. Cardiff, M.M. Shen, and C. Abate-Shen Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis Cancer Res. 62 2002 2999 3004
-
(2002)
Cancer Res.
, vol.62
, pp. 2999-3004
-
-
Kim, M.J.1
Bhatia-Gaur, R.2
Banach-Petrosky, W.A.3
Desai, N.4
Wang, Y.5
Hayward, S.W.6
Cunha, G.R.7
Cardiff, R.D.8
Shen, M.M.9
Abate-Shen, C.10
-
34
-
-
11244283209
-
The role of fibroblast growth factors and their receptors in prostate cancer
-
B. Kwabi-Addo, M. Ozen, and M. Ittmann The role of fibroblast growth factors and their receptors in prostate cancer Endocr.-Relat. Cancer 11 2004 709 724
-
(2004)
Endocr.-Relat. Cancer
, vol.11
, pp. 709-724
-
-
Kwabi-Addo, B.1
Ozen, M.2
Ittmann, M.3
-
35
-
-
1642382833
-
Notch signaling: Control of cell communication and cell fate
-
E.C. Lai Notch signaling: control of cell communication and cell fate Development 131 2004 965 973
-
(2004)
Development
, vol.131
, pp. 965-973
-
-
Lai, E.C.1
-
36
-
-
0036385832
-
Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation
-
M.L. Lamm, W.S. Catbagan, R.J. Laciak, D.H. Barnett, C.M. Hebner, W. Gaffield, D. Walterhouse, P. Iannaccone, and W. Bushman Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation Dev. Biol. 249 2002 349 366
-
(2002)
Dev. Biol.
, vol.249
, pp. 349-366
-
-
Lamm, M.L.1
Catbagan, W.S.2
Laciak, R.J.3
Barnett, D.H.4
Hebner, C.M.5
Gaffield, W.6
Walterhouse, D.7
Iannaccone, P.8
Bushman, W.9
-
37
-
-
4344661366
-
Hath1, down-regulated in colon adenocarcinomas, inhibits proliferation and tumorigenesis of colon cancer cells
-
C.C. Leow, M.S. Romero, S. Ross, P. Polakis, and W.Q. Gao Hath1, down-regulated in colon adenocarcinomas, inhibits proliferation and tumorigenesis of colon cancer cells Cancer Res. 64 2004 6050 6057
-
(2004)
Cancer Res.
, vol.64
, pp. 6050-6057
-
-
Leow, C.C.1
Romero, M.S.2
Ross, S.3
Polakis, P.4
Gao, W.Q.5
-
38
-
-
0034621824
-
Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1
-
Y.M. Li, M. Xu, M.T. Lai, Q. Huang, J.L. Castro, J. DiMuzio-Mower, T. Harrison, C. Lellis, A. Nadin, J.G. Neduvelil, R.B. Register, M.K. Sardana, M.S. Shearman, A.L. Smith, X.P. Shi, K.C. Yin, J.A. Shafer, and S.J. Gardell Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1 Nature 405 2000 689 694
-
(2000)
Nature
, vol.405
, pp. 689-694
-
-
Li, Y.M.1
Xu, M.2
Lai, M.T.3
Huang, Q.4
Castro, J.L.5
Dimuzio-Mower, J.6
Harrison, T.7
Lellis, C.8
Nadin, A.9
Neduvelil, J.G.10
Register, R.B.11
Sardana, M.K.12
Shearman, M.S.13
Smith, A.L.14
Shi, X.P.15
Yin, K.C.16
Shafer, J.A.17
Gardell, S.J.18
-
40
-
-
0037271081
-
Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila
-
C.A. Micchelli, W.P. Esler, W.T. Kimberly, C. Jack, O. Berezovska, A. Kornilova, B.T. Hyman, N. Perrimon, and M.S. Wolfe Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila FASEB J. 17 2003 79 81
-
(2003)
FASEB J.
, vol.17
, pp. 79-81
-
-
Micchelli, C.A.1
Esler, W.P.2
Kimberly, W.T.3
Jack, C.4
Berezovska, O.5
Kornilova, A.6
Hyman, B.T.7
Perrimon, N.8
Wolfe, M.S.9
-
41
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
M. Nicolas, A. Wolfer, K. Raj, J.A. Kummer, P. Mill, M. van Noort, C.C. Hui, H. Clevers, G.P. Dotto, and F. Radtke Notch1 functions as a tumor suppressor in mouse skin Nat. Genet. 33 2003 416 421
-
(2003)
Nat. Genet.
, vol.33
, pp. 416-421
-
-
Nicolas, M.1
Wolfer, A.2
Raj, K.3
Kummer, J.A.4
Mill, P.5
Van Noort, M.6
Hui, C.C.7
Clevers, H.8
Dotto, G.P.9
Radtke, F.10
-
42
-
-
0032915458
-
Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
-
D. Nofziger, A. Miyamoto, K.M. Lyons, and G. Weinmaster Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts Development 126 1999 1689 1702
-
(1999)
Development
, vol.126
, pp. 1689-1702
-
-
Nofziger, D.1
Miyamoto, A.2
Lyons, K.M.3
Weinmaster, G.4
-
43
-
-
18644367748
-
Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1
-
M. Okochi, H. Steiner, A. Fukumori, H. Tanii, T. Tomita, T. Tanaka, T. Iwatsubo, T. Kudo, M. Takeda, and C. Haass Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1 EMBO J. 21 2002 5408 5416
-
(2002)
EMBO J.
, vol.21
, pp. 5408-5416
-
-
Okochi, M.1
Steiner, H.2
Fukumori, A.3
Tanii, H.4
Tomita, T.5
Tanaka, T.6
Iwatsubo, T.7
Kudo, T.8
Takeda, M.9
Haass, C.10
-
44
-
-
0029942842
-
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
-
W.S. Pear, J.C. Aster, M.L. Scott, R.P. Hasserjian, B. Soffer, J. Sklar, and D. Baltimore Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles J. Exp. Med. 183 1996 2283 2291
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2283-2291
-
-
Pear, W.S.1
Aster, J.C.2
Scott, M.L.3
Hasserjian, R.P.4
Soffer, B.5
Sklar, J.6
Baltimore, D.7
-
45
-
-
0033136040
-
Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium
-
C.A. Podlasek, D.H. Barnett, J.Q. Clemens, P.M. Bak, and W. Bushman Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium Dev. Biol. 209 1999 28 39
-
(1999)
Dev. Biol.
, vol.209
, pp. 28-39
-
-
Podlasek, C.A.1
Barnett, D.H.2
Clemens, J.Q.3
Bak, P.M.4
Bushman, W.5
-
46
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumour suppressor?
-
F. Radtke, and K. Raj The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat. Rev., Cancer. 3 2003 756 767
-
(2003)
Nat. Rev., Cancer.
, vol.3
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
47
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
F. Radtke, A. Wilson, G. Stark, M. Bauer, J. van Meerwijk, H.R. MacDonald, and M. Aguet Deficient T cell fate specification in mice with an induced inactivation of Notch1 Immunity 10 1999 547 558
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, F.1
Wilson, A.2
Stark, G.3
Bauer, M.4
Van Meerwijk, J.5
MacDonald, H.R.6
Aguet, M.7
-
48
-
-
0023909745
-
Fos-associated protein p39 is the product of the jun proto-oncogene
-
F.J. Rauscher III, D.R. Cohen, T. Curran, T.J. Bos, P.K. Vogt, D. Bohmann, R. Tjian, and B.R. Franza Jr. Fos-associated protein p39 is the product of the jun proto-oncogene Science 240 1988 1010 1016
-
(1988)
Science
, vol.240
, pp. 1010-1016
-
-
Rauscher III, F.J.1
Cohen, D.R.2
Curran, T.3
Bos, T.J.4
Vogt, P.K.5
Bohmann, D.6
Tjian, R.7
Franza Jr., B.R.8
-
49
-
-
13144250150
-
Prostate stem cell antigen: A cell surface marker overexpressed in prostate cancer
-
R.E. Reiter, Z. Gu, T. Watabe, G. Thomas, K. Szigeti, E. Davis, M. Wahl, S. Nisitani, J. Yamashiro, M.M. Le Beau, M. Loda, and O.N. Witte Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer Proc. Natl. Acad. Sci. U. S. A. 95 1998 1735 1740
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 1735-1740
-
-
Reiter, R.E.1
Gu, Z.2
Watabe, T.3
Thomas, G.4
Szigeti, K.5
Davis, E.6
Wahl, M.7
Nisitani, S.8
Yamashiro, J.9
Le Beau, M.M.10
Loda, M.11
Witte, O.N.12
-
50
-
-
4944241544
-
JAGGED1 expression is associated with prostate cancer metastasis and recurrence
-
S. Santagata, F. Demichelis, A. Riva, S. Varambally, M.D. Hofer, J.L. Kutok, R. Kim, J. Tang, J.E. Montie, A.M. Chinnaiyan, M.A. Rubin, and J.C. Aster JAGGED1 expression is associated with prostate cancer metastasis and recurrence Cancer Res. 64 2004 6854 6857
-
(2004)
Cancer Res.
, vol.64
, pp. 6854-6857
-
-
Santagata, S.1
Demichelis, F.2
Riva, A.3
Varambally, S.4
Hofer, M.D.5
Kutok, J.L.6
Kim, R.7
Tang, J.8
Montie, J.E.9
Chinnaiyan, A.M.10
Rubin, M.A.11
Aster, J.C.12
-
51
-
-
0030841919
-
Androgenic induction of prostate-specific antigen gene is repressed by protein-protein interaction between the androgen receptor and AP-1/c-Jun in the human prostate cancer cell line LNCaP
-
N. Sato, M.D. Sadar, N. Bruchovsky, F. Saatcioglu, P.S. Rennie, S. Sato, P.H. Lange, and M.E. Gleave Androgenic induction of prostate-specific antigen gene is repressed by protein-protein interaction between the androgen receptor and AP-1/c-Jun in the human prostate cancer cell line LNCaP J. Biol. Chem. 272 1997 17485 17494
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17485-17494
-
-
Sato, N.1
Sadar, M.D.2
Bruchovsky, N.3
Saatcioglu, F.4
Rennie, P.S.5
Sato, S.6
Lange, P.H.7
Gleave, M.E.8
-
52
-
-
12144290810
-
Prostate pathology of genetically engineered mice: Definitions and classification. the consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee
-
S.B. Shappell, G.V. Thomas, R.L. Roberts, R. Herbert, M.M. Ittmann, M.A. Rubin, P.A. Humphrey, J.P. Sundberg, N. Rozengurt, R. Barrios, J.M. Ward, and R.D. Cardiff Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee Cancer Res. 64 2004 2270 2305
-
(2004)
Cancer Res.
, vol.64
, pp. 2270-2305
-
-
Shappell, S.B.1
Thomas, G.V.2
Roberts, R.L.3
Herbert, R.4
Ittmann, M.M.5
Rubin, M.A.6
Humphrey, P.A.7
Sundberg, J.P.8
Rozengurt, N.9
Barrios, R.10
Ward, J.M.11
Cardiff, R.D.12
-
53
-
-
0034254585
-
L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity
-
M.S. Shearman, D. Beher, E.E. Clarke, H.D. Lewis, T. Harrison, P. Hunt, A. Nadin, A.L. Smith, G. Stevenson, and J.L. Castro L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity Biochemistry 39 2000 8698 8704
-
(2000)
Biochemistry
, vol.39
, pp. 8698-8704
-
-
Shearman, M.S.1
Beher, D.2
Clarke, E.E.3
Lewis, H.D.4
Harrison, T.5
Hunt, P.6
Nadin, A.7
Smith, A.L.8
Stevenson, G.9
Castro, J.L.10
-
54
-
-
0035476048
-
Dynamics of notch expression during murine prostate development and tumorigenesis
-
J. Shou, S. Ross, H. Koeppen, F. de Sauvage, and W.-Q. Gao Dynamics of notch expression during murine prostate development and tumorigenesis Cancer Res. 61 2001 7291 7297
-
(2001)
Cancer Res.
, vol.61
, pp. 7291-7297
-
-
Shou, J.1
Ross, S.2
Koeppen, H.3
De Sauvage, F.4
Gao, W.-Q.5
-
55
-
-
0028216808
-
Notch1 is essential for postimplantation development in mice
-
P.J. Swiatek, C.E. Lindsell, F.F. del Amo, G. Weinmaster, and T. Gridley Notch1 is essential for postimplantation development in mice Genes Dev. 8 1994 707 719
-
(1994)
Genes Dev.
, vol.8
, pp. 707-719
-
-
Swiatek, P.J.1
Lindsell, C.E.2
Del Amo, F.F.3
Weinmaster, G.4
Gridley, T.5
-
56
-
-
0036713311
-
Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation
-
C. Talora, D.C. Sgroi, C.P. Crum, and G.P. Dotto Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation Genes Dev. 16 2002 2252 2263
-
(2002)
Genes Dev.
, vol.16
, pp. 2252-2263
-
-
Talora, C.1
Sgroi, D.C.2
Crum, C.P.3
Dotto, G.P.4
-
57
-
-
15444349656
-
High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralizing monoclonal antibody against FGF 8
-
A. Tanaka, A. Furuya, M. Yamasaki, N. Hanai, K. Kuriki, T. Kamiakito, Y. Kobayashi, H. Yoshida, M. Koike, and M. Fukayama High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralizing monoclonal antibody against FGF 8 Cancer Res 58 1998 2053 2056
-
(1998)
Cancer Res
, vol.58
, pp. 2053-2056
-
-
Tanaka, A.1
Furuya, A.2
Yamasaki, M.3
Hanai, N.4
Kuriki, K.5
Kamiakito, T.6
Kobayashi, Y.7
Yoshida, H.8
Koike, M.9
Fukayama, M.10
-
58
-
-
0032825023
-
Prostatic growth and development are regulated by FGF10
-
A.A. Thomson, and G.R. Cunha Prostatic growth and development are regulated by FGF10 Development 126 1999 3693 3701
-
(1999)
Development
, vol.126
, pp. 3693-3701
-
-
Thomson, A.A.1
Cunha, G.R.2
-
59
-
-
0036928732
-
Prostate stem cell antigen is a marker of late intermediate prostate epithelial cells
-
C.P. Tran, C. Lin, J. Yamashiro, and R.E. Reiter Prostate stem cell antigen is a marker of late intermediate prostate epithelial cells Mol. Cancer Res. 1 2002 113 121
-
(2002)
Mol. Cancer Res.
, vol.1
, pp. 113-121
-
-
Tran, C.P.1
Lin, C.2
Yamashiro, J.3
Reiter, R.E.4
-
60
-
-
0034983287
-
Increased expression of FGF-8 isoforms and FGF receptors in human premalignant prostatic intraepithelial neoplasia lesions and prostate cancer
-
E.M. Valve, M.T. Nevalainen, M.J. Nurmi, M.K. Laato, P.M. Martikainen, and P.L. Harkonen Increased expression of FGF-8 isoforms and FGF receptors in human premalignant prostatic intraepithelial neoplasia lesions and prostate cancer Lab. Invest. 81 2001 815 826
-
(2001)
Lab. Invest.
, vol.81
, pp. 815-826
-
-
Valve, E.M.1
Nevalainen, M.T.2
Nurmi, M.J.3
Laato, M.K.4
Martikainen, P.M.5
Harkonen, P.L.6
-
61
-
-
20544460148
-
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
J.H. van Es, M.E. van Gijn, O. Riccio, M. van den Born, M. Vooijs, H. Begthel, M. Cozijnsen, S. Robine, D.J. Winton, F. Radtke, and H. Clevers Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells Nature 435 2005 959 963
-
(2005)
Nature
, vol.435
, pp. 959-963
-
-
Van Es, J.H.1
Van Gijn, M.E.2
Riccio, O.3
Van Den Born, M.4
Vooijs, M.5
Begthel, H.6
Cozijnsen, M.7
Robine, S.8
Winton, D.J.9
Radtke, F.10
Clevers, H.11
-
62
-
-
0026464555
-
Colocalization of basal and luminal cell-type cytokeratins in human prostate cancer
-
A.P. Verhagen, F.C. Ramaekers, T.W. Aalders, H.E. Schaafsma, F.M. Debruyne, and J.A. Schalken Colocalization of basal and luminal cell-type cytokeratins in human prostate cancer Cancer Res. 52 1992 6182 6187
-
(1992)
Cancer Res.
, vol.52
, pp. 6182-6187
-
-
Verhagen, A.P.1
Ramaekers, F.C.2
Aalders, T.W.3
Schaafsma, H.E.4
Debruyne, F.M.5
Schalken, J.A.6
-
63
-
-
0035495974
-
Cell differentiation lineage in the prostate
-
Y. Wang, S. Hayward, M. Cao, K. Thayer, and G. Cunha Cell differentiation lineage in the prostate Differentiation 68 2001 270 279
-
(2001)
Differentiation
, vol.68
, pp. 270-279
-
-
Wang, Y.1
Hayward, S.2
Cao, M.3
Thayer, K.4
Cunha, G.5
-
64
-
-
0038381478
-
Inhibition of epithelial ductal branching in the prostate by sonic hedgehog is indirectly mediated by stromal cells
-
B.E. Wang, J. Shou, S. Ross, H. Koeppen, F.J. De Sauvage, and W.Q. Gao Inhibition of epithelial ductal branching in the prostate by sonic hedgehog is indirectly mediated by stromal cells J. Biol. Chem. 278 2003 18506 18513
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 18506-18513
-
-
Wang, B.E.1
Shou, J.2
Ross, S.3
Koeppen, H.4
De Sauvage, F.J.5
Gao, W.Q.6
-
65
-
-
2642533802
-
Notch1-expressing cells are indispensable for prostatic branching morphogenesis during development and re-growth following castration and androgen replacement
-
X.D. Wang, J. Shou, P. Wong, D.M. French, and W.Q. Gao Notch1-expressing cells are indispensable for prostatic branching morphogenesis during development and re-growth following castration and androgen replacement J. Biol. Chem. 279 2004 24733 24744
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24733-24744
-
-
Wang, X.D.1
Shou, J.2
Wong, P.3
French, D.M.4
Gao, W.Q.5
-
66
-
-
0037039316
-
Growth, regeneration, and tumorigenesis of the prostate activates the PSCA promoter
-
T. Watabe, M. Lin, H. Ide, A.A. Donjacour, G.R. Cunha, O.N. Witte, and R.E. Reiter Growth, regeneration, and tumorigenesis of the prostate activates the PSCA promoter Proc. Natl. Acad. Sci. U. S. A. 99 2002 401 406
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 401-406
-
-
Watabe, T.1
Lin, M.2
Ide, H.3
Donjacour, A.A.4
Cunha, G.R.5
Witte, O.N.6
Reiter, R.E.7
-
67
-
-
0842324623
-
Multiple niches for Notch in cancer: Context is everything
-
A.P. Weng, and J.C. Aster Multiple niches for Notch in cancer: context is everything Curr. Opin. Genet. Dev. 14 2004 48 54
-
(2004)
Curr. Opin. Genet. Dev.
, vol.14
, pp. 48-54
-
-
Weng, A.P.1
Aster, J.C.2
-
68
-
-
0017759258
-
Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle
-
D. Yaffe, and O. Saxel Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle Nature 270 1977 725 727
-
(1977)
Nature
, vol.270
, pp. 725-727
-
-
Yaffe, D.1
Saxel, O.2
-
69
-
-
0033535555
-
Neurogenic phenotypes and altered Notch processing in Drosophila presenilin mutants
-
Y. Ye, N. Lukinova, and M.E. Fortini Neurogenic phenotypes and altered Notch processing in Drosophila presenilin mutants Nature 398 1999 525 529
-
(1999)
Nature
, vol.398
, pp. 525-529
-
-
Ye, Y.1
Lukinova, N.2
Fortini, M.E.3
-
70
-
-
6044257251
-
Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues: Implications for prostate carcinogenesis and progression of prostate cancer
-
Z. Zhigang, and S. Wenlv Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues: implications for prostate carcinogenesis and progression of prostate cancer Jpn. J. Clin. Oncol. 34 2004 414 419
-
(2004)
Jpn. J. Clin. Oncol.
, vol.34
, pp. 414-419
-
-
Zhigang, Z.1
Wenlv, S.2
|