-
1
-
-
23844538993
-
The pathobiology of amyotrophic lateral sclerosis: A proteinopathy
-
Strong MJ, Kesavapany S, Pant HC. The pathobiology of amyotrophic lateral sclerosis: A proteinopathy? J Neuropathol Exp Neurol. 2005; 64: 649-64
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 649-664
-
-
Strong, M.J.1
Kesavapany, S.2
Pant, H.C.3
-
2
-
-
79955774490
-
Rate of familial amyotrophic lateral sclerosis: A systematic review and meta-Analysis
-
Byrne S, Walsh C, Lynch C, Bede P, Elamin M, Kenna K, et al. Rate of familial amyotrophic lateral sclerosis: A systematic review and meta-Analysis. JNeurol Neurosurg Psychiatry. 2011; 82: 623-7
-
(2011)
J Neurol Neurosurg Psychiatry
, vol.82
, pp. 623-627
-
-
Byrne, S.1
Walsh, C.2
Lynch, C.3
Bede, P.4
Elamin, M.5
Kenna, K.6
-
3
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen D R, Siddique T, Patterson D, Figlewicz D A, Sapp P, Hentati A, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 1993; 362: 59-62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
-
4
-
-
42649120983
-
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
-
Kabashi E, Valdmanis PN, Dion P, Spiegelman D, McConkey BJ, Vande Velde C, et al. TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat Genet. 2008; 40: 572-4
-
(2008)
Nat Genet
, vol.40
, pp. 572-574
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
Spiegelman, D.4
McConkey, B.J.5
Vande Velde, C.6
-
5
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
Sreedharan J, Blair IP, Tripathi VB, Hu X, Vance C, Rogelj B, et al. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science. 2008; 319: 1668-72
-
(2008)
Science
, vol.319
, pp. 1668-1672
-
-
Sreedharan, J.1
Blair, I.P.2
Tripathi, V.B.3
Hu, X.4
Vance, C.5
Rogelj, B.6
-
6
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
Kwiatkowski TJ Jr, Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, Russ C, et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science. 2009; 323: 1205-8
-
(2009)
Science
, vol.323
, pp. 1205-1208
-
-
Kwiatkowski Jr., T.J.1
Bosco, D.A.2
Leclerc, A.L.3
Tamrazian, E.4
Vanderburg, C.R.5
Russ, C.6
-
7
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
Vance C, Rogelj B, Hortobagyi T, de Vos K J, Nishimura AL, Sreedharan J, et al. Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science. 2009; 323: 1208-11
-
(2009)
Science
, vol.323
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobagyi, T.3
De Vos, K.J.4
Nishimura, A.L.5
Sreedharan, J.6
-
8
-
-
80052580969
-
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
-
Deng HX, Chen W, Hong ST, Boycott KM, Gorrie GH, Siddique N, et al. Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature. 2011; 477: 211-5
-
(2011)
Nature
, vol.477
, pp. 211-215
-
-
Deng, H.X.1
Chen, W.2
Hong, S.T.3
Boycott, K.M.4
Gorrie, G.H.5
Siddique, N.6
-
9
-
-
77952419246
-
Mutations of optineurin in amyotrophic lateral sclerosis
-
Maruyama H, Morino H, Ito H, Izumi Y, Kato H, Watanabe Y, et al. Mutations of optineurin in amyotrophic lateral sclerosis. Nature. 2010; 465: 223-6
-
(2010)
Nature
, vol.465
, pp. 223-226
-
-
Maruyama, H.1
Morino, H.2
Ito, H.3
Izumi, Y.4
Kato, H.5
Watanabe, Y.6
-
10
-
-
42049120518
-
Progranulin genetic variability contributes to amyotrophic lateral sclerosis
-
Sleegers K, Brouwers N, Maurer-Stroh S, van Es MA, Van Damme P, Van Vught PW, et al. Progranulin genetic variability contributes to amyotrophic lateral sclerosis. Neurology. 2008; 71: 253-9
-
(2008)
Neurology
, vol.71
, pp. 253-259
-
-
Sleegers, K.1
Brouwers, N.2
Maurer-Stroh, S.3
Van Es, M.A.4
Van Damme, P.5
Van Vught, P.W.6
-
11
-
-
84865235172
-
Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis
-
Wu C H, Fallini C, Ticozzi N, Keagle P J, Sapp P C, Piotrowska K, et al. Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis. Nature. 2012; 488: 499-503
-
(2012)
Nature
, vol.488
, pp. 499-503
-
-
Wu, C.H.1
Fallini, C.2
Ticozzi, N.3
Keagle, P.J.4
Sapp, P.C.5
Piotrowska, K.6
-
12
-
-
62549146705
-
Anovel mutation in the senataxin gene identified in a Chinese patient with sporadic amyotrophic lateral sclerosis
-
Zhao ZH, Chen WZ, Wu ZY, Wang N, Zhao G X, Chen WJ, et al. Anovel mutation in the senataxin gene identified in a Chinese patient with sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2009; 10: 118-22
-
(2009)
Amyotroph Lateral Scler
, vol.10
, pp. 118-122
-
-
Zhao, Z.H.1
Chen, W.Z.2
Wu, Z.Y.3
Wang, N.4
Zhao, G.X.5
Chen, W.J.6
-
13
-
-
78649941297
-
Exome sequencing reveals VCP mutations as a cause of familial ALS
-
Johnson JO, Mandrioli J, Benatar M, Abramzon Y, Van Deerlin VM, Trojanowski JQ, et al. Exome sequencing reveals VCP mutations as a cause of familial ALS. Neuron. 2010; 68: 857-64
-
(2010)
Neuron
, vol.68
, pp. 857-864
-
-
Johnson, J.O.1
Mandrioli, J.2
Benatar, M.3
Abramzon, Y.4
Van Deerlin, V.M.5
Trojanowski, J.Q.6
-
14
-
-
84881364742
-
Detection of a novel frameshift mutation and regions with homozygosis within ARHGEF28 gene in familial amyotrophic lateral sclerosis
-
Droppelmann CA, Wang J, Campos-Melo D, Keller B, Volkening K, Hegele RA, et al. Detection of a novel frameshift mutation and regions with homozygosis within ARHGEF28 gene in familial amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener. 2013; 14: 444-51
-
(2013)
Amyotroph Lateral Scler Frontotemporal Degener
, vol.14
, pp. 444-451
-
-
Droppelmann, C.A.1
Wang, J.2
Campos-Melo, D.3
Keller, B.4
Volkening, K.5
Hegele, R.A.6
-
15
-
-
84875605133
-
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
-
Kim HJ, Kim NC, Wang Y D, Scarborough EA, Moore J, Diaz Z, et al. Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature. 2013; 495: 467-73
-
(2013)
Nature
, vol.495
, pp. 467-473
-
-
Kim, H.J.1
Kim, N.C.2
Wang, Y.D.3
Scarborough, E.A.4
Moore, J.5
Diaz, Z.6
-
16
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in non-coding region of C9orf72 causes chromosome 9p-linked FTD and ALS
-
DeJesus-Hernandez M, Mackenzie IR, Boeve BF, Boxer AL, Baker M, Rutherford NJ, et al. Expanded GGGGCC hexanucleotide repeat in non-coding region of C9orf72 causes chromosome 9p-linked FTD and ALS. Neuron. 2011; 72: 245-56
-
(2011)
Neuron
, vol.72
, pp. 245-256
-
-
DeJesus-Hernandez, M.1
Mackenzie, I.R.2
Boeve, B.F.3
Boxer, A.L.4
Baker, M.5
Rutherford, N.J.6
-
17
-
-
80054837386
-
Ahexanucleotide repeat expansion in C9orf72 is the cause of chromosome 9p21-linked ALS-FTD
-
Renton A E, Majounie E, Waite A, Simon-Sanchez J, Rollinson S, Gibbs JR, et al. Ahexanucleotide repeat expansion in C9orf72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron. 2011; 72: 257-68
-
(2011)
Neuron
, vol.72
, pp. 257-268
-
-
Renton, A.E.1
Majounie, E.2
Waite, A.3
Simon-Sanchez, J.4
Rollinson, S.5
Gibbs, J.R.6
-
18
-
-
84878556716
-
Protein aggregation in amyotrophic lateral sclerosis
-
Blokhuis AM, Groen E J, Koppers M, Van Den Berg L H, Pasterkamp RJ. Protein aggregation in amyotrophic lateral sclerosis. Acta Neuropathol. 2013; 125: 777-94
-
(2013)
Acta Neuropathol
, vol.125
, pp. 777-794
-
-
Blokhuis, A.M.1
Groen, E.J.2
Koppers, M.3
Van Den Berg, L.H.4
Pasterkamp, R.J.5
-
19
-
-
71049166754
-
The evidence for altered RNA metabolism in amyotrophic lateral sclerosis (ALS
-
Strong MJ. The evidence for altered RNA metabolism in amyotrophic lateral sclerosis (ALS). JNeurol Sci. 2010; 288: 1-12
-
(2010)
J Neurol Sci
, vol.288
, pp. 1-12
-
-
Strong, M.J.1
-
20
-
-
84862115153
-
Misregulated RNA processing in amyotrophic lateral sclerosis
-
Polymenidou M, Lagier-Tourenne C, Hutt K R, Bennett CF, Cleveland DW, Yeo GW. Misregulated RNA processing in amyotrophic lateral sclerosis. Brain Res. 2012; 1462: 3-15
-
(2012)
Brain Res
, vol.1462
, pp. 3-15
-
-
Polymenidou, M.1
Lagier-Tourenne, C.2
Hutt, K.R.3
Bennett, C.F.4
Cleveland, D.W.5
Yeo, G.W.6
-
21
-
-
77954690411
-
RNA processing pathways in amyotrophic lateral sclerosis
-
Van Blitterswijk M, Landers J E. RNA processing pathways in amyotrophic lateral sclerosis. Neurogenetics. 2010; 11: 275-90
-
(2010)
Neurogenetics
, vol.11
, pp. 275-290
-
-
Van Blitterswijk, M.1
Landers, J.E.2
-
22
-
-
84862908655
-
Ayeast functional screen predicts new candidate ALS disease genes
-
Couthouis J, Hart MP, Shorter J, DeJesus-Hernandez M, Erion R, Oristano R, et al. Ayeast functional screen predicts new candidate ALS disease genes. Proc Natl Acad Sci U S A. 2011; 108: 20881-90
-
(2011)
Proc Natl Acad Sci U S.A.
, vol.108
, pp. 20881-20890
-
-
Couthouis, J.1
Hart, M.P.2
Shorter, J.3
DeJesus-Hernandez, M.4
Erion, R.5
Oristano, R.6
-
23
-
-
84870993605
-
The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients
-
Collins M, Riascos D, Kovalik T, An J, Krupa K, Hood BL, et al. The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients. Acta Neuropathol. 2012; 124: 717-32
-
(2012)
Acta Neuropathol
, vol.124
, pp. 717-732
-
-
Collins, M.1
Riascos, D.2
Kovalik, T.3
An, J.4
Krupa, K.5
Hood, B.L.6
-
24
-
-
84868137686
-
Rho guanine nucleotide exchange factor is an NFLmRNA destabilizing factor that forms cytoplasmic inclusions in amyotrophic lateral sclerosis
-
Droppelmann CA, Keller BA, Campos-Melo D, Volkening K, Strong MJ. Rho guanine nucleotide exchange factor is an NFLmRNA destabilizing factor that forms cytoplasmic inclusions in amyotrophic lateral sclerosis. Neurobiol Aging. 2013; 34: 248-62
-
(2013)
Neurobiol Aging
, vol.34
, pp. 248-262
-
-
Droppelmann, C.A.1
Keller, B.A.2
Campos-Melo, D.3
Volkening, K.4
Strong, M.J.5
-
25
-
-
84870994113
-
Co-Aggregation of RNA binding proteins in ALS spinal motor neurons: Evidence of a common pathogenic mechanism
-
Keller BA, Volkening K, Droppelmann CA, Ang LC, Rademakers R, Strong MJ. Co-Aggregation of RNA binding proteins in ALS spinal motor neurons: Evidence of a common pathogenic mechanism. Acta Neuropathol. 2012; 124: 733-47
-
(2012)
Acta Neuropathol
, vol.124
, pp. 733-747
-
-
Keller, B.A.1
Volkening, K.2
Droppelmann, C.A.3
Ang, L.C.4
Rademakers, R.5
Strong, M.J.6
-
26
-
-
84885808774
-
RNA toxicity from the ALS/ FTD C9orf72 expansion is mitigated by antisense intervention
-
Donnelly CJ, Zhang PW, Pham JT, Heusler AR, Mistry NA, Vidensky S, et al. RNA toxicity from the ALS/ FTD C9orf72 expansion is mitigated by antisense intervention. Neuron. 2013; 80: 415-28
-
(2013)
Neuron
, vol.80
, pp. 415-428
-
-
Donnelly, C.J.1
Zhang, P.W.2
Pham, J.T.3
Heusler, A.R.4
Mistry, N.A.5
Vidensky, S.6
-
27
-
-
84890233174
-
Hexanucleotide repeats in als/ftd form length-dependent rna foci, sequester rna binding proteins, and are neurotoxic
-
Lee Y B, Chen HJ, Peres JN, Gomez-Deza J, Attig J, Stalekar M, et al. Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic. Cell Rep. 2013; 12: 1178-86
-
(2013)
Cell Rep
, vol.12
, pp. 1178-1186
-
-
Lee, Y.B.1
Chen, H.J.2
Peres, J.N.3
Gomez-Deza, J.4
Attig, J.5
Stalekar, M.6
-
28
-
-
0036512117
-
Messenger-RNAbinding proteins and the messages they carry
-
Dreyfuss G, Kim V N, Kataoka N. Messenger-RNAbinding proteins and the messages they carry. Nat Rev Mol Cell Biol. 2002; 3: 195-205
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 195-205
-
-
Dreyfuss, G.1
Kim, V.N.2
Kataoka, N.3
-
29
-
-
38449102667
-
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease
-
Buratti E, Baralle FE. Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease. Front Biosci. 2008; 13: 867-78
-
(2008)
Front Biosci
, vol.13
, pp. 867-878
-
-
Buratti, E.1
Baralle, F.E.2
-
30
-
-
84860863883
-
TDP-43 and FUS RNAbinding proteins bind distinct sets of cytoplasmic messenger RNAs and differently regulate their post-Transcriptional fate in motoneuron-like cells
-
Colombrita C, Onesto E, Megiorni F, Pizzuti A, Baralle FE, Buratti E, et al. TDP-43 and FUS RNAbinding proteins bind distinct sets of cytoplasmic messenger RNAs and differently regulate their post-Transcriptional fate in motoneuron-like cells. JBiol Chem. 2012; 287: 15635-47
-
(2012)
J Biol Chem
, vol.287
, pp. 15635-15647
-
-
Colombrita, C.1
Onesto, E.2
Megiorni, F.3
Pizzuti, A.4
Baralle, F.E.5
Buratti, E.6
-
31
-
-
84857772495
-
TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes
-
Kawahara Y, Mieda-Sato A. TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes. Proc Natl Acad Sci U S A. 2012; 109: 3347-52
-
(2012)
Proc Natl Acad Sci U S.A.
, vol.109
, pp. 3347-3352
-
-
Kawahara, Y.1
Mieda-Sato, A.2
-
32
-
-
84871002507
-
FUS stimulates microRNA biogenesis by facilitating cotranscriptional Drosha recruitment
-
Morlando M, Dini Modigliani S, Torrelli G, Rosa A, Di Carlo V, Caffarelli E, et al. FUS stimulates microRNA biogenesis by facilitating cotranscriptional Drosha recruitment. EMBO J. 2012; 31: 4502-10
-
(2012)
EMBO J.
, vol.31
, pp. 4502-4510
-
-
Morlando, M.1
Dini Modigliani, S.2
Torrelli, G.3
Rosa, A.4
Di Carlo, V.5
Caffarelli, E.6
-
33
-
-
33745945163
-
Tls ews and taf15: A model for transcriptional integration of gene expression
-
Law W J, Cann K L, Hicks G G. TLS, EWS and TAF15: A model for transcriptional integration of gene expression. Brief Funct Genomic Proteomic. 2006; 5: 8-14
-
(2006)
Brief Funct Genomic Proteomic
, vol.5
, pp. 8-14
-
-
Law, W.J.1
Cann, K.L.2
Hicks, G.G.3
-
34
-
-
80055038803
-
Afraction of the transcription factor TAF15 participates in interactions with a subset of the spliceosomal U1 snRNP complex
-
Leichter M, Marko M, Ganou V, Patrinou-Georgoula M, Tora L, Guialis A. Afraction of the transcription factor TAF15 participates in interactions with a subset of the spliceosomal U1 snRNP complex. Biochim Biophys Acta. 2011; 1814: 1812-24
-
(2011)
Biochim Biophys Acta
, vol.1814
, pp. 1812-1824
-
-
Leichter, M.1
Marko, M.2
Ganou, V.3
Patrinou-Georgoula, M.4
Tora, L.5
Guialis, A.6
-
35
-
-
84884907673
-
Taf15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through mirnas
-
Ballarino M, Jobert L, Dembele D, de la G range P, Auboeuf D, Tora L. TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs. Oncogene. 2013; 32: 4646-55
-
(2013)
Oncogene
, vol.32
, pp. 4646-4655
-
-
Ballarino, M.1
Jobert, L.2
Dembele, D.3
De La Grange, P.4
Auboeuf, D.5
Tora, L.6
-
36
-
-
70350135049
-
TDP-43 is recruited to stress granules in conditions of oxidative insult
-
Colombrita C, Zennaro E, Fallini C, Weber M, Sommacal A, Buratti E, et al. TDP-43 is recruited to stress granules in conditions of oxidative insult. JNeurochem. 2009; 111: 1051-61
-
(2009)
J Neurochem
, vol.111
, pp. 1051-1061
-
-
Colombrita, C.1
Zennaro, E.2
Fallini, C.3
Weber, M.4
Sommacal, A.5
Buratti, E.6
-
37
-
-
84866671948
-
Gene expression responses to fus ews and taf15 reduction and stress granule sequestration analyses identifies fet-protein non-redundant functions
-
Blechingberg J, Luo Y, Bolund L, Damgaard CK, Nielsen AL. Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions. PLoS One. 2012; 7: E46251
-
(2012)
PLoS One
, vol.7
-
-
Blechingberg, J.1
Luo, Y.2
Bolund, L.3
Damgaard, C.K.4
Nielsen, A.L.5
-
38
-
-
55549130760
-
Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways
-
Arimoto K, Fukuda H, Imajoh-Ohmi S, Saito H, Takekawa M. Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways. Nat Cell Biol. 2008; 10: 1324-32
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1324-1332
-
-
Arimoto, K.1
Fukuda, H.2
Imajoh-Ohmi, S.3
Saito, H.4
Takekawa, M.5
-
39
-
-
77950686223
-
Ogfod1, anovel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress
-
Wehner KA, Schutz S, Sarnow P. OGFOD1, anovel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress. Mol Cell Biol. 2010; 30: 2006-16
-
(2010)
Mol Cell Biol
, vol.30
, pp. 2006-2016
-
-
Wehner, K.A.1
Schutz, S.2
Sarnow, P.3
-
40
-
-
84885441032
-
Ribonuclease/angiogenin inhibitor 1 regulates stress-induced subcellular localization of angiogenin to control growth and survival
-
Pizzo E, Sarcinelli C, Sheng J, Fusco S, Formiggini F, Netti P, et al. Ribonuclease/angiogenin inhibitor 1 regulates stress-induced subcellular localization of angiogenin to control growth and survival. JCell Sci. 2013; 126: 4308-19
-
(2013)
J Cell Sci
, vol.126
, pp. 4308-4319
-
-
Pizzo, E.1
Sarcinelli, C.2
Sheng, J.3
Fusco, S.4
Formiggini, F.5
Netti, P.6
-
41
-
-
33947210861
-
Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2-Alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs
-
Solomon S, Xu Y, Wang B, David MD, Schubert P, Kennedy D, et al. Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2-Alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs. Mol Cell Biol. 2007; 27: 2324-42
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2324-2342
-
-
Solomon, S.1
Xu, Y.2
Wang, B.3
David, M.D.4
Schubert, P.5
Kennedy, D.6
-
42
-
-
33847417585
-
P-bodies and the control of mRNA translation and degradation
-
Parker R, Sheth U. P-bodies and the control of mRNA translation and degradation. Mol Cell. 2007; 25: 635-46
-
(2007)
Mol Cell
, vol.25
, pp. 635-646
-
-
Parker, R.1
Sheth, U.2
-
43
-
-
22344455246
-
Stress granules and processing bodies are dynamically linked sites of mrnp remodelling
-
Kedersha N, Stoecklin G, Ayodele M, Yacono P, Lykke-Andersen J, Fritzler MJ, et al. Stress granules and processing bodies are dynamically linked sites of mRNP remodelling. JCell Biol. 2005; 169: 871-84
-
(2005)
J Cell Biol
, vol.169
, pp. 871-884
-
-
Kedersha, N.1
Stoecklin, G.2
Ayodele, M.3
Yacono, P.4
Lykke-Andersen, J.5
Fritzler, M.J.6
-
44
-
-
39949085583
-
Stress granules: The Tao of RNA triage
-
Anderson P, Kedersha N. Stress granules: The Tao of RNA triage. Trends Biochem Sci. 2008; 33: 141-50
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 141-150
-
-
Anderson, P.1
Kedersha, N.2
-
45
-
-
0036154218
-
Evidence that ternary complex (eif2-gtp-Trna(i) (met))-deficient preinitiation complexes are core constituents of mammalian stress granules
-
Kedersha N, Chen S, Gilks N, Li W, Miller I J, Stahl J, et a l. Evidence that ternary complex (eIF2-GTP-TRNA(i) (Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell. 2002; 13: 195-210
-
(2002)
Mol Biol Cell
, vol.13
, pp. 195-210
-
-
Kedersha, N.1
Chen, S.2
Gilks, N.3
Li, W.4
Miller, I.J.5
Stahl, J.6
-
46
-
-
0033611157
-
RNAbinding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules
-
Kedersha NL, Gupta M, Li W, Miller I, Anderson P. RNAbinding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules. JCell Biol. 1999; 147: 1431-42
-
(1999)
J Cell Biol
, vol.147
, pp. 1431-1442
-
-
Kedersha, N.L.1
Gupta, M.2
Li, W.3
Miller, I.4
Anderson, P.5
-
47
-
-
16844365216
-
The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules
-
Wilczynska A, Aigueperse C, Kress M, Dautry F, Weil D. The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules. JCell Sci. 2005; 118: 981-92
-
(2005)
J Cell Sci
, vol.118
, pp. 981-992
-
-
Wilczynska, A.1
Aigueperse, C.2
Kress, M.3
Dautry, F.4
Weil, D.5
-
48
-
-
34247229733
-
Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules
-
Nonhoff U, Ralser M, Welzel F, Piccini I, Balzereit D, Yaspo ML, et al. Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules. Mol Biol Cell. 2007; 18: 1385-96
-
(2007)
Mol Biol Cell
, vol.18
, pp. 1385-1396
-
-
Nonhoff, U.1
Ralser, M.2
Welzel, F.3
Piccini, I.4
Balzereit, D.5
Yaspo, M.L.6
-
49
-
-
1942471656
-
MK2-induced tristetraprolin: 14-3-3 complexes prevent stress granule association and AREmRNA decay
-
Stoecklin G, Stubbs T, Kedersha N, Wax S, Rigby WF, Blackwell TK, et al. MK2-induced tristetraprolin: 14-3-3 complexes prevent stress granule association and AREmRNA decay. EMBO J. 2004; 23: 1313-24
-
(2004)
EMBO J.
, vol.23
, pp. 1313-1324
-
-
Stoecklin, G.1
Stubbs, T.2
Kedersha, N.3
Wax, S.4
Rigby, W.F.5
Blackwell, T.K.6
-
50
-
-
33751256265
-
ZBP1 regulates mRNA stability during cellular stress
-
Stohr N, Lederer M, Reinke C, Meyer S, Hatzfeld M, Singer RH, et al. ZBP1 regulates mRNA stability during cellular stress. JCell Biol. 2006; 175: 527-34
-
(2006)
J Cell Biol
, vol.175
, pp. 527-534
-
-
Stohr, N.1
Lederer, M.2
Reinke, C.3
Meyer, S.4
Hatzfeld, M.5
Singer, R.H.6
-
51
-
-
33845295461
-
Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules
-
Leung AK, Calabrese J M, Sharp P A. Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc Natl Acad Sci U S A. 2006; 103: 18125-30
-
(2006)
Proc Natl Acad Sci U S.A.
, vol.103
, pp. 18125-18130
-
-
Leung, A.K.1
Calabrese, J.M.2
Sharp, P.A.3
-
52
-
-
0037451173
-
The RasGAP-Associated endoribonuclease G3BP assembles stress granules
-
Tourriere H, Chebli K, Zekri L, Courselaud B, Blanchard JM, Bertrand E, et al. The RasGAP-Associated endoribonuclease G3BP assembles stress granules. JCell Biol. 2003; 160: 823-31
-
(2003)
J Cell Biol
, vol.160
, pp. 823-831
-
-
Tourriere, H.1
Chebli, K.2
Zekri, L.3
Courselaud, B.4
Blanchard, J.M.5
Bertrand, E.6
-
53
-
-
34548550361
-
The exon-junction-complex-component metastatic lymph node 51 functions in stress-granule assembly
-
Baguet A, Degot S, Cougot N, Bertrand E, Chenard MP, Wendling C, et al. The exon-junction-complex-component metastatic lymph node 51 functions in stress-granule assembly. JCell Sci. 2007; 120: 2774-84
-
(2007)
J Cell Sci
, vol.120
, pp. 2774-2784
-
-
Baguet, A.1
Degot, S.2
Cougot, N.3
Bertrand, E.4
Chenard, M.P.5
Wendling, C.6
-
54
-
-
33847352972
-
An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response
-
Yu C, York B, Wang S, Feng Q, Xu J, O'Malley BW. An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Mol Cell. 2007; 25: 765-78
-
(2007)
Mol Cell
, vol.25
, pp. 765-778
-
-
Yu, C.1
York, B.2
Wang, S.3
Feng, Q.4
Xu, J.5
O'Malley, B.W.6
-
55
-
-
33845231583
-
Polysome-bound endonuclease PMR1 is targeted to stress granules via stress-specific binding to TIA-1
-
Yang F, Peng Y, Murray E L, Otsuka Y, Kedersha N, Schoenberg DR. Polysome-bound endonuclease PMR1 is targeted to stress granules via stress-specific binding to TIA-1. Mol Cell Biol. 2006; 26: 8803-13
-
(2006)
Mol Cell Biol
, vol.26
, pp. 8803-8813
-
-
Yang, F.1
Peng, Y.2
Murray, E.L.3
Otsuka, Y.4
Kedersha, N.5
Schoenberg, D.R.6
-
56
-
-
70350367745
-
Unravelling the ultrastructure of stress granules and associated P-bodies in human cells
-
Souquere S, Mollet S, Kress M, Dautry F, Pierron G, Weil D. Unravelling the ultrastructure of stress granules and associated P-bodies in human cells. JCell Sci. 2009; 122: 3619-26
-
(2009)
J Cell Sci
, vol.122
, pp. 3619-3626
-
-
Souquere, S.1
Mollet, S.2
Kress, M.3
Dautry, F.4
Pierron, G.5
Weil, D.6
-
57
-
-
34547883878
-
Mouse hepatitis coronavirus replication induces host translational shut-off and mRNA decay, with concomitant formation of stress granules and processing bodies
-
Raaben M, Groot Koerkamp MJ, Rottier PJ, de Haan CA. Mouse hepatitis coronavirus replication induces host translational shut-off and mRNA decay, with concomitant formation of stress granules and processing bodies. Cell Microbiol. 2007; 9: 2218-29
-
(2007)
Cell Microbiol
, vol.9
, pp. 2218-2229
-
-
Raaben, M.1
Groot Koerkamp, M.J.2
Rottier, P.J.3
De Haan, C.A.4
-
59
-
-
0034638837
-
Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules
-
Kedersha N, Cho M R, Li W, Yacono P W, Chen S, Gilks N, et al. Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules. JCell Biol. 2000; 151: 1257-68
-
(2000)
J Cell Biol
, vol.151
, pp. 1257-1268
-
-
Kedersha, N.1
Cho, M.R.2
Li, W.3
Yacono, P.W.4
Chen, S.5
Gilks, N.6
-
60
-
-
2442566370
-
Cytoplasmic foci are sites of mRNA decay in human cells
-
Cougot N, Babajko S, Seraphin B. Cytoplasmic foci are sites of mRNA decay in human cells. JCell Biol. 2004; 165: 31-40
-
(2004)
J Cell Biol
, vol.165
, pp. 31-40
-
-
Cougot, N.1
Babajko, S.2
Seraphin, B.3
-
61
-
-
17844371700
-
Arole for eIF4E and eIF4E-Transporter in targeting mRNPs to mammalian processing bodies
-
Andrei MA, Ingelfinger D, Heintzmann R, Achsel T, Rivera-Pomar R, Luhrmann R. Arole for eIF4E and eIF4E-Transporter in targeting mRNPs to mammalian processing bodies. RNA. 2005; 11: 717-27
-
(2005)
RNA
, vol.11
, pp. 717-727
-
-
Andrei, M.A.1
Ingelfinger, D.2
Heintzmann, R.3
Achsel, T.4
Rivera-Pomar, R.5
Luhrmann, R.6
-
62
-
-
0031030491
-
Amouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates
-
Bashkirov VI, Scherthan H, Solinger JA, Buerstedde JM, Heyer WD. Amouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates. JCell Biol. 1997; 136: 761-73
-
(1997)
J Cell Biol
, vol.136
, pp. 761-773
-
-
Bashkirov, V.I.1
Scherthan, H.2
Solinger, J.A.3
Buerstedde, J.M.4
Heyer, W.D.5
-
63
-
-
0037121926
-
Human Dcp2 a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures
-
Van Dijk E, Cougot N, Meyer S, Babajko S, Wahle E, Seraphin B. Human Dcp2: A catalytically active mRNA decapping enzyme located in specific cytoplasmic structures. EMBO J. 2002; 21: 6915-24
-
(2002)
EMBO J.
, vol.21
, pp. 6915-6924
-
-
Van Dijk, E.1
Cougot, N.2
Meyer, S.3
Babajko, S.4
Wahle, E.5
Seraphin, B.6
-
64
-
-
47549087539
-
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
-
Zheng D, Ezzeddine N, Chen CY, Zhu W, He X, Shyu A B. Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells. JCell Biol. 2008; 182: 89-101
-
(2008)
J Cell Biol
, vol.182
, pp. 89-101
-
-
Zheng, D.1
Ezzeddine, N.2
Chen, C.Y.3
Zhu, W.4
He, X.5
Shyu, A.B.6
-
65
-
-
84873537120
-
Relationship of GW/P-bodies with stress granules
-
Stoecklin G, Kedersha N. Relationship of GW/P-bodies with stress granules. Adv Exp Med Biol. 2013; 768: 197-211
-
(2013)
Adv Exp Med Biol
, vol.768
, pp. 197-211
-
-
Stoecklin, G.1
Kedersha, N.2
-
67
-
-
56149086182
-
P-bodies promote stress granule assembly in Saccharomyces cerevisiae
-
Buchan JR, Muhlrad D, Parker R. P-bodies promote stress granule assembly in Saccharomyces cerevisiae. JCell Biol. 2008; 183: 441-55
-
(2008)
J Cell Biol
, vol.183
, pp. 441-455
-
-
Buchan, J.R.1
Muhlrad, D.2
Parker, R.3
-
68
-
-
34547860022
-
GW body disassembly triggered by siRNAs independently of their silencing activity
-
Serman A, Le Roy F, Aigueperse C, Kress M, Dautry F, Weil D. GW body disassembly triggered by siRNAs independently of their silencing activity. Nucleic Acids Res. 2007; 35: 4715-27
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 4715-4727
-
-
Serman, A.1
Le Roy, F.2
Aigueperse, C.3
Kress, M.4
Dautry, F.5
Weil, D.6
-
69
-
-
59549094064
-
Structural determinants of the cellular localization and shuttling of TDP-43
-
Ayala Y M, Zago P, D'Ambrogio A, Xu Y F, Petrucelli L, Buratti E, et al. Structural determinants of the cellular localization and shuttling of TDP-43. JCell Sci. 2008; 121: 3778-85
-
(2008)
J Cell Sci
, vol.121
, pp. 3778-3785
-
-
Ayala, Y.M.1
Zago, P.2
D'Ambrogio, A.3
Xu, Y.F.4
Petrucelli, L.5
Buratti, E.6
-
70
-
-
0030746523
-
TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling
-
Zinszner H, Sok J, Immanuel D, Yin Y, Ron D. TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling. JCell Sci. 1997; 110: 1741-50
-
(1997)
J Cell Sci
, vol.110
, pp. 1741-1750
-
-
Zinszner, H.1
Sok, J.2
Immanuel, D.3
Yin, Y.4
Ron, D.5
-
71
-
-
78149461229
-
Tar DNA binding protein-43 (TDP-43) associates with stress granules: Analysis of cultured cells and pathological brain tissue
-
Liu-Yesucevitz L, Bilgutay A, Zhang YJ, Vanderweyde T, Citro A, Mehta T, et al. Tar DNA binding protein-43 (TDP-43) associates with stress granules: Analysis of cultured cells and pathological brain tissue. PLoS One. 2010; 5: E13250
-
(2010)
PLoS One
, vol.5
-
-
Liu-Yesucevitz, L.1
Bilgutay, A.2
Zhang, Y.J.3
Vanderweyde, T.4
Citro, A.5
Mehta, T.6
-
72
-
-
76149120427
-
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery
-
Freibaum BD, Chitta RK, High A A, Taylor JP. Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. JProteome Res. 2010; 9: 1104-20
-
(2010)
J Proteome Res
, vol.9
, pp. 1104-1120
-
-
Freibaum, B.D.1
Chitta, R.K.2
High, A.A.3
Taylor, J.P.4
-
73
-
-
79952268025
-
TDP-43 is directed to stress granules by sorbitol, anovel physiological osmotic and oxidative stressor
-
Dewey CM, Cenik B, Sephton CF, Dries DR, Mayer P 3rd, Good SK, et al. TDP-43 is directed to stress granules by sorbitol, anovel physiological osmotic and oxidative stressor. Mol Cell Biol. 2011; 31: 1098-108
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1098-1108
-
-
Dewey, C.M.1
Cenik, B.2
Sephton, C.F.3
Dries, D.R.4
Mayer III, P.5
Good, S.K.6
-
74
-
-
79961117695
-
C-Jun N-Terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress
-
Meyerowitz J, Parker S J, Vella L J, Ng D, Price KA, Liddell JR, et al. C-Jun N-Terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress. Mol Neurodegener. 2011; 6: 57
-
(2011)
Mol Neurodegener
, vol.6
, pp. 57
-
-
Meyerowitz, J.1
Parker, S.J.2
Vella, L.J.3
Ng, D.4
Price, K.A.5
Liddell, J.R.6
-
75
-
-
79952589652
-
TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1
-
McDonald KK, Aulas A, Destroismaisons L, Pickles S, Beleac E, Camu W, et al. TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1. Hum Mol Genet. 2011; 20: 1400-10
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1400-1410
-
-
McDonald, K.K.1
Aulas, A.2
Destroismaisons, L.3
Pickles, S.4
Beleac, E.5
Camu, W.6
-
76
-
-
84867686875
-
Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP
-
Aulas A, Stabile S, VandeVelde C. Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP. Mol Neurodegener. 2012; 7: 54
-
(2012)
Mol Neurodegener
, vol.7
, pp. 54
-
-
Aulas, A.1
Stabile, S.2
VandeVelde, C.3
-
77
-
-
84863309952
-
Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNAbinding protein of 43 kDa (TDP-43
-
Bentmann E, Neumann M, Tahirovic S, Rodde R, Dormann D, Haass C. Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNAbinding protein of 43 kDa (TDP-43). JBiol Chem. 2012; 287: 23079-94
-
(2012)
J Biol Chem
, vol.287
, pp. 23079-23094
-
-
Bentmann, E.1
Neumann, M.2
Tahirovic, S.3
Rodde, R.4
Dormann, D.5
Haass, C.6
-
78
-
-
73649148708
-
Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43
-
Nishimoto Y, Ito D, Yagi T, Nihei Y, Tsunoda Y, Suzuki N. Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43. JBiol Chem. 2010; 285: 608-19
-
(2010)
J Biol Chem
, vol.285
, pp. 608-619
-
-
Nishimoto, Y.1
Ito, D.2
Yagi, T.3
Nihei, Y.4
Tsunoda, Y.5
Suzuki, N.6
-
79
-
-
84869005887
-
The effect of PRMT1-mediated arginine methylation on the subcellular localization, stress granules, and detergent-insoluble aggregates of FUS/TLS
-
Yamaguchi A, Kitajo K. The effect of PRMT1-mediated arginine methylation on the subcellular localization, stress granules, and detergent-insoluble aggregates of FUS/TLS. PLoS One. 2012; 7: E49267
-
(2012)
PLoS One
, vol.7
-
-
Yamaguchi, A.1
Kitajo, K.2
-
80
-
-
84881220788
-
FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress
-
Sama RR, Ward CL, Kaushansky LJ, Lemay N, Ishigaki S, Urano F, et al. FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress. JCell Physiol. 2013; 228: 2222-31
-
(2013)
J Cell Physiol
, vol.228
, pp. 2222-2231
-
-
Sama, R.R.1
Ward, C.L.2
Kaushansky, L.J.3
Lemay, N.4
Ishigaki, S.5
Urano, F.6
-
81
-
-
80053646130
-
Nuclear localization sequence of FUS and induction of stress granules by ALS mutants
-
e27-40
-
Gal J, Zhang J, Kwinter D M, Zhai J, Jia H, Jia J, et a l. Nuclear localization sequence of FUS and induction of stress granules by ALS mutants. Neurobiol Aging. 2011; 32: 2323, e27-40
-
(2011)
Neurobiol Aging
, vol.32
, pp. 2323
-
-
Gal, J.1
Zhang, J.2
Kwinter, D.M.3
Zhai, J.4
Jia, H.5
Jia, J.6
-
82
-
-
77957867303
-
Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules
-
Bosco D A, Lemay N, Ko H K, Zhou H, Burke C, Kwiatkowski TJ Jr, et al. Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules. Hum Mol Genet. 2010; 19: 4160-75
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4160-4175
-
-
Bosco, D.A.1
Lemay, N.2
Ko, H.K.3
Zhou, H.4
Burke, C.5
Kwiatkowski Jr., T.J.6
-
83
-
-
77955792022
-
ALS-Associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
-
Dormann D, Rodde R, Edbauer D, Bentmann E, Fischer I, Hruscha A, et al. ALS-Associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import. EMBO J. 2010; 29: 2841-57
-
(2010)
EMBO J.
, vol.29
, pp. 2841-2857
-
-
Dormann, D.1
Rodde, R.2
Edbauer, D.3
Bentmann, E.4
Fischer, I.5
Hruscha, A.6
-
84
-
-
84883149037
-
Amyotrophic lateral sclerosis-linked FUS/ TLS alters stress granule assembly and dynamics
-
Baron DM, Kaushansky L J, Ward C L, Sama R R, Chian RJ, Boggio KJ, et al. Amyotrophic lateral sclerosis-linked FUS/ TLS alters stress granule assembly and dynamics. Mol Neurodegener. 2013; 8: 30
-
(2013)
Mol Neurodegener
, vol.8
, pp. 30
-
-
Baron, D.M.1
Kaushansky, L.J.2
Ward, C.L.3
Sama, R.R.4
Chian, R.J.5
Boggio, K.J.6
-
85
-
-
48249083430
-
The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
-
Andersson MK, Stahlberg A, Arvidsson Y, Olofsson A, Semb H, Stenman G, et al. The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response. BMC Cell Biol. 2008; 9: 37
-
(2008)
BMC Cell Biol
, vol.9
, pp. 37
-
-
Andersson, M.K.1
Stahlberg, A.2
Arvidsson, Y.3
Olofsson, A.4
Semb, H.5
Stenman, G.6
-
86
-
-
84864547364
-
Domains involved in TAF15 subcellular localization: Dependence on cell type and ongoing transcription
-
Marko M, Vlassis A, Guialis A, Leichter M. Domains involved in TAF15 subcellular localization: Dependence on cell type and ongoing transcription. Gene. 2012; 506: 331-8
-
(2012)
Gene
, vol.506
, pp. 331-338
-
-
Marko, M.1
Vlassis, A.2
Guialis, A.3
Leichter, M.4
-
87
-
-
12344317072
-
An integrative approach to gain insights into the cellular function of human Ataxin-2
-
Ralser M, Albrecht M, Nonhoff U, Lengauer T, Lehrach H, Krobitsch S. An integrative approach to gain insights into the cellular function of human Ataxin-2. J Mol Biol. 2005; 346: 203-14
-
(2005)
J Mol Biol
, vol.346
, pp. 203-214
-
-
Ralser, M.1
Albrecht, M.2
Nonhoff, U.3
Lengauer, T.4
Lehrach, H.5
Krobitsch, S.6
-
89
-
-
77956155218
-
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
-
Elden A C, Kim HJ, Hart MP, Chen-Plotkin AS, Johnson BS, Fang X, et al. Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. Nature. 2010; 466: 1069-75
-
(2010)
Nature
, vol.466
, pp. 1069-1075
-
-
Elden, A.C.1
Kim, H.J.2
Hart, M.P.3
Chen-Plotkin, A.S.4
Johnson, B.S.5
Fang, X.6
-
90
-
-
0026470789
-
Aputative atp-dependent rna helicase involved in saccharomyces cerevisiae ribosome assembly
-
Ripmaster TL, Vaughn G P, Woolford J L J r. Aputative ATP-dependent RNA helicase involved in Saccharomyces cerevisiae ribosome assembly. Proc Natl Acad Sci USA. 1992; 89: 11131-5
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11131-11135
-
-
Ripmaster, T.L.1
Vaughn, G.P.2
Woolford Jr., J.L.3
-
91
-
-
33749493493
-
Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2-Alpha phosphorylation
-
Mazroui R, Sukarieh R, Bordeleau ME, Kaufman RJ, Northcote P, Tanaka J, et al. Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2-Alpha phosphorylation. Mol Biol Cell. 2006; 17: 4212-9
-
(2006)
Mol Biol Cell
, vol.17
, pp. 4212-4219
-
-
Mazroui, R.1
Sukarieh, R.2
Bordeleau, M.E.3
Kaufman, R.J.4
Northcote, P.5
Tanaka, J.6
-
92
-
-
84857124994
-
Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates
-
Parker SJ, Meyerowitz J, James JL, Liddell JR, Crouch PJ, Kanninen KM, et al. Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates. Neurochem Int. 2012; 60: 415-24
-
(2012)
Neurochem Int
, vol.60
, pp. 415-424
-
-
Parker, S.J.1
Meyerowitz, J.2
James, J.L.3
Liddell, J.R.4
Crouch, P.J.5
Kanninen, K.M.6
-
93
-
-
73949134014
-
Tar dna binding protein of 43 kda (tdp-43), 14-3-3 proteins and copper/zinc superoxide dismutase (sod1) interact to modulate nflmrna stability implications for altered rna processing in amyotrophic lateral sclerosis (als
-
Volkening K, Leystra-Lantz C, Yang W, Jaffee H, Strong MJ. TAR DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFLmRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS). Brain Res. 2009; 1305: 168-82
-
(2009)
Brain Res
, vol.1305
, pp. 168-182
-
-
Volkening, K.1
Leystra-Lantz, C.2
Yang, W.3
Jaffee, H.4
Strong, M.J.5
-
94
-
-
0032568793
-
Acritical role for amino-Terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion
-
DePace AH, Santoso A, Hillner P, Weissman JS. Acritical role for amino-Terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion. Cell. 1998; 93: 1241-52
-
(1998)
Cell
, vol.93
, pp. 1241-1252
-
-
DePace, A.H.1
Santoso, A.2
Hillner, P.3
Weissman, J.S.4
-
95
-
-
80155157847
-
The seeds of neurodegeneration: Prion-like spreading in ALS
-
Polymenidou M, Cleveland DW. The seeds of neurodegeneration: Prion-like spreading in ALS. Cell. 2011; 147: 498-508
-
(2011)
Cell
, vol.147
, pp. 498-508
-
-
Polymenidou, M.1
Cleveland, D.W.2
-
96
-
-
84862151933
-
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
-
King O D, Gitler AD, Shorter J. The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease. Brain Res. 2012; 1462: 61-80
-
(2012)
Brain Res
, vol.1462
, pp. 61-80
-
-
King, O.D.1
Gitler, A.D.2
Shorter, J.3
-
97
-
-
84890331414
-
Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones
-
Udan-Johns M, Bengoechea R, Bell S, Shao J, Diamond MI, True HL, et al. Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones. Hum Mol Genet. 2013; 23: 157-70
-
(2013)
Hum Mol Genet
, vol.23
, pp. 157-170
-
-
Udan-Johns, M.1
Bengoechea, R.2
Bell, S.3
Shao, J.4
Diamond, M.I.5
True, H.L.6
-
98
-
-
67749133873
-
TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity
-
Johnson B S, Snead D, Lee J J, McCaffery J M, Shorter J, Gitler AD. TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity. JBiol Chem. 2009; 284: 20329-39
-
(2009)
J Biol Chem
, vol.284
, pp. 20329-20339
-
-
Johnson, B.S.1
Snead, D.2
Lee, J.J.3
McCaffery, J.M.4
Shorter, J.5
Gitler, A.D.6
-
99
-
-
79960040173
-
An ALS-Associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity
-
Guo W, Chen Y, Zhou X, Kar A, Ray P, Chen X, et al. An ALS-Associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity. Nat Struct Mol Biol. 2011; 18: 822-30
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 822-830
-
-
Guo, W.1
Chen, Y.2
Zhou, X.3
Kar, A.4
Ray, P.5
Chen, X.6
-
100
-
-
84878565260
-
ALS mutant FUS disrupts nuclear localization and sequesters wild-Type FUS within cytoplasmic stress granules
-
Vance C, Scotter EL, Nishimura AL, Troakes C, Mitchell JC, Kathe C, et al. ALS mutant FUS disrupts nuclear localization and sequesters wild-Type FUS within cytoplasmic stress granules. Hum Mol Genet. 2013; 22: 2676-88
-
(2013)
Hum Mol Genet
, vol.22
, pp. 2676-2688
-
-
Vance, C.1
Scotter, E.L.2
Nishimura, A.L.3
Troakes, C.4
Mitchell, J.C.5
Kathe, C.6
-
101
-
-
84880706463
-
Exposure to environmental toxicants and pathogenesis of amyotrophic lateral sclerosis: State of the art and research perspectives
-
Trojsi F, Monsurro MR, Tedeschi G. Exposure to environmental toxicants and pathogenesis of amyotrophic lateral sclerosis: State of the art and research perspectives. Int J Mol Sci. 2013; 14: 15286-311
-
(2013)
Int J Mol Sci
, vol.14
, pp. 15286-15311
-
-
Trojsi, F.1
Monsurro, M.R.2
Tedeschi, G.3
-
102
-
-
84879232244
-
Retroviruses and amyotrophic lateral sclerosis
-
Alfahad T, Nath A. Retroviruses and amyotrophic lateral sclerosis. Antiviral Res. 2013; 99: 180-7
-
(2013)
Antiviral Res
, vol.99
, pp. 180-187
-
-
Alfahad, T.1
Nath, A.2
-
103
-
-
0029257385
-
Oxidative stress, age-related neurodegeneration, and the potential for neurotrophic treatment
-
Williams LR. Oxidative stress, age-related neurodegeneration, and the potential for neurotrophic treatment. Cerebrovasc Brain Metab Rev. 1995; 7: 55-73
-
(1995)
Cerebrovasc Brain Metab Rev
, vol.7
, pp. 55-73
-
-
Williams, L.R.1
-
104
-
-
84865407887
-
Oxidative damage to RNA in aging and neurodegenerative disorders
-
Nunomura A, Moreira P I, Castellani R J, Lee H G, Zhu X, Smith MA, et al. Oxidative damage to RNA in aging and neurodegenerative disorders. Neurotox Res. 2012; 22: 231-48
-
(2012)
Neurotox Res
, vol.22
, pp. 231-248
-
-
Nunomura, A.1
Moreira, P.I.2
Castellani, R.J.3
Lee, H.G.4
Zhu, X.5
Smith, M.A.6
-
106
-
-
0022724941
-
Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease
-
Ihara Y, Nukina N, Miura R, Ogawara M. Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease. JBiochem. 1986; 99: 1807-10
-
(1986)
J Biochem
, vol.99
, pp. 1807-1810
-
-
Ihara, Y.1
Nukina, N.2
Miura, R.3
Ogawara, M.4
-
107
-
-
0025273951
-
Immunocytochemical and ultrastructural studies of Pick's disease
-
Murayama S, Mori H, Ihara Y, Tomonaga M. Immunocytochemical and ultrastructural studies of Pick's disease. Ann Neurol. 1990; 27: 394-405
-
(1990)
Ann Neurol
, vol.27
, pp. 394-405
-
-
Murayama, S.1
Mori, H.2
Ihara, Y.3
Tomonaga, M.4
-
108
-
-
0028120382
-
Senile dementia of lewy body type and alzheimer type are biochemically distinct in terms of paired helical filaments and hyperphosphorylated tau protein
-
Harrington C R, Perry R H, Perry E K, Hurt J, McKeith I G, Roth M, et al. Senile dementia of Lewy body type and Alzheimer type are biochemically distinct in terms of paired helical filaments and hyperphosphorylated tau protein. Dementia. 1994; 5: 215-28
-
(1994)
Dementia
, vol.5
, pp. 215-228
-
-
Harrington, C.R.1
Perry, R.H.2
Perry, E.K.3
Hurt, J.4
McKeith, I.G.5
Roth, M.6
-
109
-
-
0028305261
-
Argyrophilic thread-like structure in corticobasal degeneration and supranuclear palsy
-
Ikeda K, Akiyama H, Haga C, Kondo H, Arima K, Oda T. Argyrophilic thread-like structure in corticobasal degeneration and supranuclear palsy. Neurosci Lett. 1994; 174: 157-9
-
(1994)
Neurosci Lett
, vol.174
, pp. 157-159
-
-
Ikeda, K.1
Akiyama, H.2
Haga, C.3
Kondo, H.4
Arima, K.5
Oda, T.6
-
110
-
-
33745654119
-
Tau protein hyperphosphorylation in sporadic ALS with cognitive impairment
-
Strong MJ, Yang W, Strong WL, Leystra-Lantz C, Jaffe H, Pant HC. Tau protein hyperphosphorylation in sporadic ALS with cognitive impairment. Neurology. 2006; 66: 1770-1
-
(2006)
Neurology
, vol.66
, pp. 1770-1771
-
-
Strong, M.J.1
Yang, W.2
Strong, W.L.3
Leystra-Lantz, C.4
Jaffe, H.5
Pant, H.C.6
-
111
-
-
0035811050
-
Hyperphosphorylation induces self-Assembly of tau into tangles of paired helical filaments/straight filaments
-
Alonso A, Zaidi T, Novak M, Grundke-Iqbal I, Iqbal K. Hyperphosphorylation induces self-Assembly of tau into tangles of paired helical filaments/straight filaments. Proc Natl Acad Sci U S A. 2001; 98: 6923-8
-
(2001)
Proc Natl Acad Sci U S.A.
, vol.98
, pp. 6923-6928
-
-
Alonso, A.1
Zaidi, T.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
112
-
-
19944429806
-
Phosphorylation modulates the alpha-helical structure and polymerization of a peptide from the third tau microtubule-binding repeat
-
Mendieta J, Fuertes MA, Kunjishapatham R, Santa-Maria I, Moreno FJ, Alonso C, et al. Phosphorylation modulates the alpha-helical structure and polymerization of a peptide from the third tau microtubule-binding repeat. Biochim Biophys Acta. 2005; 1721: 16-26
-
(2005)
Biochim Biophys Acta
, vol.1721
, pp. 16-26
-
-
Mendieta, J.1
Fuertes, M.A.2
Kunjishapatham, R.3
Santa-Maria, I.4
Moreno, F.J.5
Alonso, C.6
-
113
-
-
67649622427
-
Pseudohyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization
-
Sun Q, Gamblin TC. Pseudohyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization. Biochemistry. 2009; 48: 6002-11
-
(2009)
Biochemistry
, vol.48
, pp. 6002-6011
-
-
Sun, Q.1
Gamblin, T.C.2
-
114
-
-
80155166000
-
Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms
-
Combs B, Voss K, Gamblin T C. Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms. Biochemistry. 2011; 50: 9446-56
-
(2011)
Biochemistry
, vol.50
, pp. 9446-9456
-
-
Combs, B.1
Voss, K.2
Gamblin, T.C.3
-
115
-
-
48749088629
-
Abnormal phosphorylation of ser409/410 of tdp-43 in ftld-u and als
-
Inukai Y, Nonaka T, Arai T, Yoshida M, Hashizume Y, Beach TG, et al. Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS. FEBS Lett. 2008; 582: 2899-904
-
(2008)
FEBS Lett
, vol.582
, pp. 2899-2904
-
-
Inukai, Y.1
Nonaka, T.2
Arai, T.3
Yoshida, M.4
Hashizume, Y.5
Beach, T.G.6
-
116
-
-
47949086625
-
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Hasegawa M, Arai T, Nonaka T, Kametani F, Yoshida M, Hashizume Y, et al. Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Ann Neurol. 2008; 64: 60-70
-
(2008)
Ann Neurol
, vol.64
, pp. 60-70
-
-
Hasegawa, M.1
Arai, T.2
Nonaka, T.3
Kametani, F.4
Yoshida, M.5
Hashizume, Y.6
-
117
-
-
59249085091
-
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies
-
Neumann M, Kwong L K, Lee E B, Kremmer E, Flatley A, Xu Y, et al. Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathol. 2009; 117: 137-49
-
(2009)
Acta Neuropathol
, vol.117
, pp. 137-149
-
-
Neumann, M.1
Kwong, L.K.2
Lee, E.B.3
Kremmer, E.4
Flatley, A.5
Xu, Y.6
-
118
-
-
78649750391
-
Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy
-
Liachko N F, Guthrie C R, Kraemer B C. Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy. JNeurosci. 2010; 30: 16208-19
-
(2010)
J Neurosci
, vol.30
, pp. 16208-16219
-
-
Liachko, N.F.1
Guthrie, C.R.2
Kraemer, B.C.3
-
119
-
-
85040709233
-
Phosphorylation regulates proteasomalmediated degradation and solubility of TAR DNA binding protein-43 C-Terminal fragments
-
Zhang YJ, Gendron TF, Xu YF, Ko L W, Yen S H, Petrucelli L. Phosphorylation regulates proteasomalmediated degradation and solubility of TAR DNA binding protein-43 C-Terminal fragments. Mol Neurodegener. 2010; 5: 33
-
(2010)
Mol Neurodegener
, vol.5
, pp. 33
-
-
Zhang, Y.J.1
Gendron, T.F.2
Xu, Y.F.3
Ko, L.W.4
Yen, S.H.5
Petrucelli, L.6
-
120
-
-
78650680776
-
Regulation of TDP-43 aggregation by phosphorylation and p62/ SQSTM1
-
Brady OA, Meng P, Zheng Y, Mao Y, Hu F. Regulation of TDP-43 aggregation by phosphorylation and p62/ SQSTM1. JNeurochem. 2011; 116: 248-59
-
(2011)
J Neurochem
, vol.116
, pp. 248-259
-
-
Brady, O.A.1
Meng, P.2
Zheng, Y.3
Mao, Y.4
Hu, F.5
-
121
-
-
77953870938
-
Amyotrophic lateral sclerosis: Dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord
-
Braak H, Ludolph A, Thal DR, del Tredici K. Amyotrophic lateral sclerosis: Dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord. Acta Neuropathol. 2010; 120: 67-74
-
(2010)
Acta Neuropathol
, vol.120
, pp. 67-74
-
-
Braak, H.1
Ludolph, A.2
Thal, D.R.3
Del Tredici, K.4
-
122
-
-
79961148135
-
Hyperphosphorylation as a defence mechanism to reduce TDP-43 aggregation
-
Li H Y, Yeh P A, Chiu H C, Tang C Y, Tu B P. Hyperphosphorylation as a defence mechanism to reduce TDP-43 aggregation. PLoS One. 2011; 6: E23075
-
(2011)
PLoS One
, vol.6
-
-
Li, H.Y.1
Yeh, P.A.2
Chiu, H.C.3
Tang, C.Y.4
Tu, B.P.5
-
123
-
-
84893012138
-
TDP-43 Phosphorylation by casein kinase I{epsilon} promotes oligomerization and enhances toxicity in vivo
-
Choksi DK, Roy B, Chatterjee S, Yusuff T, Bakhoum MF, Sengupta U, et al. TDP-43 Phosphorylation by casein kinase I{epsilon} promotes oligomerization and enhances toxicity in vivo. Hum Mol Genet. 2014; 23: 1025-35
-
(2014)
Hum Mol Genet
, vol.23
, pp. 1025-1035
-
-
Choksi, D.K.1
Roy, B.2
Chatterjee, S.3
Yusuff, T.4
Bakhoum, M.F.5
Sengupta, U.6
-
124
-
-
0033579464
-
Sequence and structure-based prediction of eukaryotic protein phosphorylation sites
-
Blom N, Gammeltoft S, Brunak S. Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. JMol Biol. 1999; 294: 135-62
-
(1999)
J Mol Biol
, vol.294
, pp. 135-162
-
-
Blom, N.1
Gammeltoft, S.2
Brunak, S.3
-
125
-
-
84860149496
-
De novo design of synthetic prion domains
-
Toombs J A, Petri M, Paul K R, Kan G Y, Ben-Hur A, Ross ED. De novo design of synthetic prion domains. Proc Natl Acad Sci U S A. 2012; 109: 6519-24
-
(2012)
Proc Natl Acad Sci U S.A.
, vol.109
, pp. 6519-6524
-
-
Toombs, J.A.1
Petri, M.2
Paul, K.R.3
Kan, G.Y.4
Ben-Hur, A.5
Ross, E.D.6
-
126
-
-
24044515001
-
FoldIndex: A simple tool to predict whether a given protein sequence is intrinsically unfolded
-
Prilusky J, Felder CE, Zeev-Ben-Mordehai T, Rydberg EH, Man O, Beckmann JS, et al. FoldIndex: A simple tool to predict whether a given protein sequence is intrinsically unfolded. Bioinformatics. 2005; 21: 3435-8
-
(2005)
Bioinformatics
, vol.21
, pp. 3435-3438
-
-
Prilusky, J.1
Felder, C.E.2
Zeev-Ben-Mordehai, T.3
Rydberg, E.H.4
Man, O.5
Beckmann, J.S.6
-
127
-
-
15944406765
-
Sumo: A history of modification
-
Hay RT. SUMO: A history of modification. Mol Cell. 2005; 18: 1-12
-
(2005)
Mol Cell
, vol.18
, pp. 1-12
-
-
Hay, R.T.1
-
128
-
-
3943099375
-
Protein modification by SUMO
-
Johnson ES. Protein modification by SUMO. Annu Rev Biochem. 2004; 73: 355-82
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 355-382
-
-
Johnson, E.S.1
-
129
-
-
36349022018
-
Emerging extranuclear roles of protein SUMOylation in neuronal function and dysfunction
-
Martin S, Wilkinson KA, Nishimune A, Henley JM. Emerging extranuclear roles of protein SUMOylation in neuronal function and dysfunction. Nat Rev Neurosci. 2007; 8: 948-59
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 948-959
-
-
Martin, S.1
Wilkinson, K.A.2
Nishimune, A.3
Henley, J.M.4
-
130
-
-
80455155035
-
SUMO2/3 conjugation is an endogenous neuroprotective mechanism
-
Datwyler AL, Lattig-Tunnemann G, Yang W, Paschen W, Lee SL, Dirnagl U, et al. SUMO2/3 conjugation is an endogenous neuroprotective mechanism. JCereb Blood Flow Metab. 2011; 31: 2152-9
-
(2011)
J Cereb Blood Flow Metab
, vol.31
, pp. 2152-2159
-
-
Datwyler, A.L.1
Lattig-Tunnemann, G.2
Yang, W.3
Paschen, W.4
Lee, S.L.5
Dirnagl, U.6
-
131
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu/Zn superoxide dismutase
-
Deng HX, Hentati A, Tainer JA, Iqbal Z, Cayabyab A, Hung WY, et al. Amyotrophic lateral sclerosis and structural defects in Cu/Zn superoxide dismutase. Science. 1993; 261: 1047-51
-
(1993)
Science
, vol.261
, pp. 1047-1051
-
-
Deng, H.X.1
Hentati, A.2
Tainer, J.A.3
Iqbal, Z.4
Cayabyab, A.5
Hung, W.Y.6
-
132
-
-
0034662807
-
Aggregates of mutant protein appear progressively in dendrites, in periaxonal processes of oligodendrocytes, and in neuronal and astrocytic perikarya of mice expressing the SOD1-G93A mutation of familial amyotrophic lateral sclerosis
-
Stieber A, Gonatas JO, Gonatas NK. Aggregates of mutant protein appear progressively in dendrites, in periaxonal processes of oligodendrocytes, and in neuronal and astrocytic perikarya of mice expressing the SOD1-G93A mutation of familial amyotrophic lateral sclerosis. JNeurol Sci. 2000; 177: 114-23
-
(2000)
J Neurol Sci
, vol.177
, pp. 114-123
-
-
Stieber, A.1
Gonatas, J.O.2
Gonatas, N.K.3
-
133
-
-
43749109844
-
Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1
-
Shaw BF, Lelie HL, Durazo A, Nersissian A M, Xu G, Chan PK, et al. Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1. JBiol Chem. 2008; 283: 8340-50
-
(2008)
J Biol Chem
, vol.283
, pp. 8340-8350
-
-
Shaw, B.F.1
Lelie, H.L.2
Durazo, A.3
Nersissian, A.M.4
Xu, G.5
Chan, P.K.6
-
134
-
-
33745924415
-
SUMO-1 modification increases human SOD1 stability and aggregation
-
Fei E, Jia N, Yan M, Ying Z, Sun Q, Wang H, et al. SUMO-1 modification increases human SOD1 stability and aggregation. Biochem Biophys Res Commun. 2006; 347: 406-12
-
(2006)
Biochem Biophys Res Commun
, vol.347
, pp. 406-412
-
-
Fei, E.1
Jia, N.2
Yan, M.3
Ying, Z.4
Sun, Q.5
Wang, H.6
-
135
-
-
77950658888
-
Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyubiquitin chains
-
Seyfried N T, Gozal Y M, Dammer E B, Xia Q, Duong D M, Cheng D, et al. Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyubiquitin chains. Mol Cell Proteomics. 2010; 9: 705-18
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 705-718
-
-
Seyfried, N.T.1
Gozal, Y.M.2
Dammer, E.B.3
Xia, Q.4
Duong, D.M.5
Cheng, D.6
-
136
-
-
67649173012
-
System-wide changes to SUMO modifications in response to heat shock
-
Golebiowski F, Matic I, Tatham MH, Cole C, Yin Y, Nakamura A, et al. System-wide changes to SUMO modifications in response to heat shock. Sci Signal. 2009; 2: Ra24
-
(2009)
Sci Signal
, vol.2
-
-
Golebiowski, F.1
Matic, I.2
Tatham, M.H.3
Cole, C.4
Yin, Y.5
Nakamura, A.6
-
137
-
-
77149134314
-
Ebp1 sumoylation, regulated by TLS/FUS E3 ligase, is required for its anti-proliferative activity
-
Oh S M, Liu Z, Okada M, Jang S W, Liu X, Chan C B, et a l. Ebp1 sumoylation, regulated by TLS/FUS E3 ligase, is required for its anti-proliferative activity. Oncogene. 2010; 29: 1017-30
-
(2010)
Oncogene
, vol.29
, pp. 1017-1030
-
-
Oh, S.M.1
Liu, Z.2
Okada, M.3
Jang, S.W.4
Liu, X.5
Chan, C.B.6
-
138
-
-
0034607653
-
C-Jun and p53 activity is modulated by SUMO-1 modification
-
Muller S, Berger M, Lehembre F, Seeler JS, Haupt Y, Dejean A. c-Jun and p53 activity is modulated by SUMO-1 modification. JBiol Chem. 2000; 275: 13321-9
-
(2000)
J Biol Chem
, vol.275
, pp. 13321-13329
-
-
Muller, S.1
Berger, M.2
Lehembre, F.3
Seeler, J.S.4
Haupt, Y.5
Dejean, A.6
-
139
-
-
0033380850
-
Cell cycle regulation of PML modification and ND10 composition
-
Everett R D, Lomonte P, Sternsdorf T, Van Driel R, Orr A. Cell cycle regulation of PML modification and ND10 composition. JCell Sci. 1999; 112: 4581-8
-
(1999)
J Cell Sci
, vol.112
, pp. 4581-4588
-
-
Everett, R.D.1
Lomonte, P.2
Sternsdorf, T.3
Van Driel, R.4
Orr, A.5
-
140
-
-
0032135131
-
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation
-
Desterro JM, Rodriguez MS, Hay RT. SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. Mol Cell. 1998; 2: 233-9
-
(1998)
Mol Cell
, vol.2
, pp. 233-239
-
-
Desterro, J.M.1
Rodriguez, M.S.2
Hay, R.T.3
-
141
-
-
33747838835
-
SUMOsp: A web server for sumoylation site prediction
-
Xue Y, Zhou F, Fu C, Xu Y, Yao X. SUMOsp: A web server for sumoylation site prediction. Nucleic Acids Res. 2006; 34: W254-7
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Xue, Y.1
Zhou, F.2
Fu, C.3
Xu, Y.4
Yao, X.5
-
142
-
-
0031603283
-
RNA and protein interactions modulated by protein arginine methylation
-
Gary J D, Clarke S. RNA and protein interactions modulated by protein arginine methylation. Prog Nucleic Acid Res Mol Biol. 1998; 61: 65-131
-
(1998)
Prog Nucleic Acid Res Mol Biol
, vol.61
, pp. 65-131
-
-
Gary, J.D.1
Clarke, S.2
-
143
-
-
67649968054
-
The protein arginine methyltransferase family: An update about function, new perspectives and the physiological role in humans
-
Wolf SS. The protein arginine methyltransferase family: An update about function, new perspectives and the physiological role in humans. Cell Mol Life Sci. 2009; 66: 2109-21
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2109-2121
-
-
Wolf, S.S.1
-
144
-
-
0034677814
-
PRMT1 is the predominant type I protein arginine methyltransferase in mammalian cells
-
J, Frankel A, Cook R J, Kim S, Paik W K, Williams KR, et al. PRMT1 is the predominant type I protein arginine methyltransferase in mammalian cells. JBiol Chem. 2000; 275: 7723-30
-
(2000)
J Biol Chem
, vol.275
, pp. 7723-7730
-
-
Tang, J.1
Frankel, A.2
Cook, R.J.3
Kim, S.4
Paik, W.K.5
Williams, K.R.6
-
145
-
-
0027156138
-
Peptides with sequences similar to glycine, arginine-rich motifs in proteins interacting with RNA are efficiently recognized by methyltransferase(s) modifying arginine in numerous proteins
-
Najbauer J, Johnson BA, Young A L, Aswad DW. Peptides with sequences similar to glycine, arginine-rich motifs in proteins interacting with RNA are efficiently recognized by methyltransferase(s) modifying arginine in numerous proteins. JBiol Chem. 1993; 268: 10501-9
-
(1993)
J Biol Chem
, vol.268
, pp. 10501-10509
-
-
Najbauer, J.1
Johnson, B.A.2
Young, A.L.3
Aswad, D.W.4
-
146
-
-
0028957320
-
In vivo and in vitro arginine methylation of RNA-binding proteins
-
Liu Q, Dreyfuss G. In vivo and in vitro arginine methylation of RNA-binding proteins. Mol Cell Biol. 1995; 15: 2800-8
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2800-2808
-
-
Liu, Q.1
Dreyfuss, G.2
-
147
-
-
0033603396
-
Regulation of transcription by a protein methyltransferase
-
Chen D, Ma H, Hong H, Koh SS, Huang SM, Schurter BT, et al. Regulation of transcription by a protein methyltransferase. Science. 1999; 284: 2174-7
-
(1999)
Science
, vol.284
, pp. 2174-2177
-
-
Chen, D.1
Ma, H.2
Hong, H.3
Koh, S.S.4
Huang, S.M.5
Schurter, B.T.6
-
148
-
-
83455162720
-
Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations
-
Tradewell ML, Yu Z, Tibshirani M, Boulanger MC, Durham HD, Richard S. Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations. Hum Mol Genet. 2012; 21: 136-49
-
(2012)
Hum Mol Genet
, vol.21
, pp. 136-149
-
-
Tradewell, M.L.1
Yu, Z.2
Tibshirani, M.3
Boulanger, M.C.4
Durham, H.D.5
Richard, S.6
-
149
-
-
84869237956
-
Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS
-
Dormann D, Madl T, Valori C F, Bentmann E, Tahirovic S, Abou-Ajram C, et al. Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS. EMBO J. 2012; 31: 4258-75
-
(2012)
EMBO J.
, vol.31
, pp. 4258-4275
-
-
Dormann, D.1
Madl, T.2
Valori, C.F.3
Bentmann, E.4
Tahirovic, S.5
Abou-Ajram, C.6
-
150
-
-
63049100536
-
PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function
-
Jobert L, Argentini M, Tora L. PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function. Exp Cell Res. 2009; 315: 1273-86
-
(2009)
Exp Cell Res
, vol.315
, pp. 1273-1286
-
-
Jobert, L.1
Argentini, M.2
Tora, L.3
-
152
-
-
77951700391
-
Nuclear factor TDP-43 can affect selected micro-RNA levels
-
Buratti E, de Conti L, Stuani C, Romano M, Baralle M, Baralle F. Nuclear factor TDP-43 can affect selected micro-RNA levels. FEBS J. 2010; 277: 2268-81
-
(2010)
FEBS J.
, vol.277
, pp. 2268-2281
-
-
Buratti, E.1
De Conti, L.2
Stuani, C.3
Romano, M.4
Baralle, M.5
Baralle, F.6
-
154
-
-
34249946434
-
The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells
-
Laneve P, di Marcotullio L, Gioia U, Fiori ME, Ferretti E, Gulino A, et al. The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells. Proc Natl Acad Sci U S A. 2007; 104: 7957-62
-
(2007)
Proc Natl Acad Sci U S.A.
, vol.104
, pp. 7957-7962
-
-
Laneve, P.1
Di Marcotullio, L.2
Gioia, U.3
Fiori, M.E.4
Ferretti, E.5
Gulino, A.6
-
155
-
-
58149375393
-
The bifunctional microRNA miR-9/miR-9 regulates REST and CoREST and is down-regulated in Huntington's disease
-
Packer A N, Xing Y, Harper SQ, Jones L, Davidson BL. The bifunctional microRNA miR-9/miR-9 regulates REST and CoREST and is down-regulated in Huntington's disease. JNeurosci. 2008; 28: 14341-6
-
(2008)
J Neurosci
, vol.28
, pp. 14341-14346
-
-
Packer, A.N.1
Xing, Y.2
Harper, S.Q.3
Jones, L.4
Davidson, B.L.5
-
156
-
-
84861653416
-
MiR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons
-
Pathania M, Torres-Reveron J, Yan L, Kimura T, Lin TV, Gordon V, et al. miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons. PLoS One. 2012; 7: E38174
-
(2012)
PLoS One
, vol.7
-
-
Pathania, M.1
Torres-Reveron, J.2
Yan, L.3
Kimura, T.4
Lin, T.V.5
Gordon, V.6
-
157
-
-
75949101467
-
Regulation of synaptic structure and function by FMRP-Associated microRNAs miR-125b and miR-132
-
Edbauer D, Neilson JR, Foster KA, Wang CF, Seeburg DP, Batterton MN, et al. Regulation of synaptic structure and function by FMRP-Associated microRNAs miR-125b and miR-132. Neuron. 2010; 65: 373-84
-
(2010)
Neuron
, vol.65
, pp. 373-384
-
-
Edbauer, D.1
Neilson, J.R.2
Foster, K.A.3
Wang, C.F.4
Seeburg, D.P.5
Batterton, M.N.6
-
158
-
-
84871590013
-
The FTD/ALS-Associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila
-
Li Z, Lu Y, Xu XL, Gao FB. The FTD/ALS-Associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila. Hum Mol Genet. 2013; 22: 218-25
-
(2013)
Hum Mol Genet
, vol.22
, pp. 218-225
-
-
Li, Z.1
Lu, Y.2
Xu, X.L.3
Gao, F.B.4
-
159
-
-
77953183812
-
ADicer-independent miRNA biogenesis pathway that requires Ago catalysis
-
Cheloufi S, Dos Santos C O, Chong M M, Hannon G J. ADicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature. 2010; 465: 584-9
-
(2010)
Nature
, vol.465
, pp. 584-589
-
-
Cheloufi, S.1
Dos Santos, C.O.2
Chong, M.M.3
Hannon, G.J.4
-
160
-
-
77953897182
-
Anovel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity
-
Cifuentes D, Xue H, Taylor D W, Patnode H, Mishima Y, CheloufiS, et al. Anovel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science. 2010; 328: 1694-8
-
(2010)
Science
, vol.328
, pp. 1694-1698
-
-
Cifuentes, D.1
Xue, H.2
Taylor, D.W.3
Patnode, H.4
Mishima, Y.5
Cheloufi, S.6
-
161
-
-
79958020894
-
Deletion of astroglial Dicer causes non-cell-Autonomous neuronal dysfunction and degeneration
-
Tao J, Wu H, Lin Q, Wei W, Lu X H, Cantle J P, et a l. Deletion of astroglial Dicer causes non-cell-Autonomous neuronal dysfunction and degeneration. JNeurosci. 2011; 31: 8306-19
-
(2011)
JNeurosci
, vol.31
, pp. 8306-8319
-
-
Tao, J.1
Wu, H.2
Lin, Q.3
Wei, W.4
Lu, X.H.5
Cantle, J.P.6
-
162
-
-
73549104488
-
Dicer ablation in oligodendrocytes provokes neuronal impairment in mice
-
Shin D, Shin J Y, McManus MT, Ptacek LJ, Fu YH. Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Ann Neurol. 2009; 66: 843-57
-
(2009)
Ann Neurol
, vol.66
, pp. 843-857
-
-
Shin, D.1
Shin, J.Y.2
McManus, M.T.3
Ptacek, L.J.4
Fu, Y.H.5
-
163
-
-
84856214569
-
Dicer-microRNA pathway is critical for peripheral nerve regeneration and functional recovery in vivo and regenerative axonogenesis in vitro
-
Wu D, Raafat A, Pak E, Clemens S, Murashov AK. Dicer-microRNA pathway is critical for peripheral nerve regeneration and functional recovery in vivo and regenerative axonogenesis in vitro. Exp Neurol. 2012; 233: 555-65
-
(2012)
Exp Neurol
, vol.233
, pp. 555-565
-
-
Wu, D.1
Raafat, A.2
Pak, E.3
Clemens, S.4
Murashov, A.K.5
-
164
-
-
84878005741
-
Altered microrna expression profile in amyotrophic lateral sclerosis: A role in the regulation of nflmrna levels
-
Campos-Melo D, Droppelmann C A, He Z, Volkening K, Strong MJ. Altered microRNA expression profile in amyotrophic lateral sclerosis: A role in the regulation of NFLmRNA levels. Mol Brain. 2013; 6: 26
-
(2013)
Mol Brain
, vol.6
, pp. 26
-
-
Campos-Melo, D.1
Droppelmann, C.A.2
He, Z.3
Volkening, K.4
Strong, M.J.5
-
165
-
-
84865536102
-
AmiRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis
-
de Felice B, Guida M, Coppola C, de Mieri G, Cotrufo R. AmiRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis. Gene. 2012; 508: 35-40
-
(2012)
Gene
, vol.508
, pp. 35-40
-
-
De Felice, B.1
Guida, M.2
Coppola, C.3
De Mieri, G.4
Cotrufo, R.5
-
166
-
-
84865987121
-
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
-
Butovsky O, Siddiqui S, Gabriely G, Lanser AJ, Dake B, Murugaiyan G, et al. Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS. JClin Invest. 2012; 122: 3063-87
-
(2012)
J Clin Invest
, vol.122
, pp. 3063-3087
-
-
Butovsky, O.1
Siddiqui, S.2
Gabriely, G.3
Lanser, A.J.4
Dake, B.5
Murugaiyan, G.6
-
167
-
-
77952336221
-
Aberrant microRNA expression in the brains of neurodegenerative diseases: MiR-29a decreased in Alzheimer's disease brains targets neurone navigator 3
-
Shioya M, Obayashi S, Tabunoki H, Arima K, Saito Y, Ishida T, et al. Aberrant microRNA expression in the brains of neurodegenerative diseases: MiR-29a decreased in Alzheimer's disease brains targets neurone navigator 3. Neuropathol Appl Neurobiol. 2010; 36: 320-30
-
(2010)
Neuropathol Appl Neurobiol
, vol.36
, pp. 320-330
-
-
Shioya, M.1
Obayashi, S.2
Tabunoki, H.3
Arima, K.4
Saito, Y.5
Ishida, T.6
-
169
-
-
72149131804
-
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice
-
Williams AH, Valdez G, Moresi V, Qi X, McAnally J, Elliott JL, et al. MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular
-
(2009)
Science
, vol.326
, pp. 1549-1554
-
-
Williams, A.H.1
Valdez, G.2
Moresi, V.3
Qi, X.4
McAnally, J.5
Elliott, J.L.6
-
170
-
-
84885357213
-
MiRNA-9 expression is up-regulated in the spinal cord of G93A-SOD1 transgenic mice
-
Zhou F, Guan Y, Chen Y, Zhang C, Yu L, Gao H, et al. miRNA-9 expression is up-regulated in the spinal cord of G93A-SOD1 transgenic mice. Int J Clin Exp Pathol. 2013; 6: 1826-38
-
(2013)
Int J Clin Exp Pathol
, vol.6
, pp. 1826-1838
-
-
Zhou, F.1
Guan, Y.2
Chen, Y.3
Zhang, C.4
Yu, L.5
Gao, H.6
-
171
-
-
84884712642
-
Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice
-
Koval ED, Shaner C, Zhang P, du Maine X, Fischer K, Tay J, et al. Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice. Hum Mol Genet. 2013; 22: 4127-35
-
(2013)
Hum Mol Genet
, vol.22
, pp. 4127-4135
-
-
Koval, E.D.1
Shaner, C.2
Zhang, P.3
Du Maine, X.4
Fischer, K.5
Tay, J.6
-
172
-
-
79953185674
-
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
-
Polymenidou M, Lagier-Tourenne C, Hutt K R, Huelga SC, Moran J, Liang TY, et al. Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nat Neurosci. 2011; 14: 459-68
-
(2011)
Nat Neurosci
, vol.14
, pp. 459-468
-
-
Polymenidou, M.1
Lagier-Tourenne, C.2
Hutt, K.R.3
Huelga, S.C.4
Moran, J.5
Liang, T.Y.6
-
173
-
-
79953180492
-
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
-
Tollervey JR, Curk T, Rogelj B, Briese M, Cereda M, Kayikci M, et al. Characterizing the RNA targets and position-dependent splicing regulation by TDP-43. Nat Neurosci. 2011; 14: 452-8
-
(2011)
Nat Neurosci
, vol.14
, pp. 452-458
-
-
Tollervey, J.R.1
Curk, T.2
Rogelj, B.3
Briese, M.4
Cereda, M.5
Kayikci, M.6
-
174
-
-
84881518613
-
Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis
-
Ishihara T, Ariizumi Y, Shiga A, Kato T, Tan C F, Sato T, et al. Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis. Hum Mol Genet. 2013; 22: 4136-47
-
(2013)
Hum Mol Genet
, vol.22
, pp. 4136-4147
-
-
Ishihara, T.1
Ariizumi, Y.2
Shiga, A.3
Kato, T.4
Tan, C.F.5
Sato, T.6
-
175
-
-
84873314088
-
Spliceosome integrity is defective in the motor neuron diseases ALS and SMA
-
Tsuiji H, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, et al. Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. EMBO Mol Med. 2013; 5: 221-34
-
(2013)
EMBO Mol Med
, vol.5
, pp. 221-234
-
-
Tsuiji, H.1
Iguchi, Y.2
Furuya, A.3
Kataoka, A.4
Hatsuta, H.5
Atsuta, N.6
-
176
-
-
0037108967
-
Higher order arrangement of the eukaryotic nuclear bodies
-
Wang IF, Reddy NM, Shen CK. Higher order arrangement of the eukaryotic nuclear bodies. Proc Natl Acad Sci USA. 2002; 99: 13583-8
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13583-13588
-
-
Wang, I.F.1
Reddy, N.M.2
Shen, C.K.3
-
177
-
-
84857997227
-
Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking
-
Cohen TJ, Hwang AW, Unger T, Trojanowski J Q, Lee V M. Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking. EMBO J. 2012; 31: 1241-52
-
(2012)
EMBO J.
, vol.31
, pp. 1241-1252
-
-
Cohen, T.J.1
Hwang, A.W.2
Unger, T.3
Trojanowski, J.Q.4
Lee, V.M.5
-
178
-
-
84863513494
-
Evolutionary origin of RNA editing
-
Gray M W. Evolutionary origin of RNA editing. Biochemistry. 2012; 51: 5235-42
-
(2012)
Biochemistry
, vol.51
, pp. 5235-5242
-
-
Gray, M.W.1
-
179
-
-
84867537101
-
A-To-I editing of protein coding and non-coding RNAs
-
Mallela A, Nishikura K. A-To-I editing of protein coding and non-coding RNAs. Crit Rev Biochem Mol Biol. 2012; 47: 493-501
-
(2012)
Crit Rev Biochem Mol Biol
, vol.47
, pp. 493-501
-
-
Mallela, A.1
Nishikura, K.2
-
180
-
-
0029775644
-
RED2, abrain-specific member of the RNA-specific adenosine deaminase family
-
Melcher T, Maas S, Herb A, Sprengel R, Higuchi M, Seeburg PH. RED2, abrain-specific member of the RNA-specific adenosine deaminase family. JBiol Chem. 1996; 271: 31795-8
-
(1996)
J Biol Chem
, vol.271
, pp. 31795-31798
-
-
Melcher, T.1
Maas, S.2
Herb, A.3
Sprengel, R.4
Higuchi, M.5
Seeburg, P.H.6
-
181
-
-
0029053578
-
Distribution of Tenr, an RNA-binding protein, in a lattice-like network within the spermatid nucleus in the mouse
-
Schumacher JM, Lee K, Edelhoff S, Braun RE. Distribution of Tenr, an RNA-binding protein, in a lattice-like network within the spermatid nucleus in the mouse. Biol Reprod. 1995; 52: 1274-83
-
(1995)
Biol Reprod
, vol.52
, pp. 1274-1283
-
-
Schumacher, J.M.1
Lee, K.2
Edelhoff, S.3
Braun, R.E.4
-
183
-
-
0025995296
-
RNA editing in brain controls a determinant of ion flow in glutamate-gated channels
-
Sommer B, Kohler M, Sprengel R, Seeburg P H. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell. 1991; 67: 11-9
-
(1991)
Cell
, vol.67
, pp. 11-19
-
-
Sommer, B.1
Kohler, M.2
Sprengel, R.3
Seeburg, P.H.4
-
184
-
-
84856580212
-
Profound down-regulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons
-
Hideyama T, Yamashita T, Aizawa H, Tsuji S, Kakita A, Takahashi H, et al. Profound down-regulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons. Neurobiol Dis. 2012; 45: 1121-8
-
(2012)
Neurobiol Dis
, vol.45
, pp. 1121-1128
-
-
Hideyama, T.1
Yamashita, T.2
Aizawa, H.3
Tsuji, S.4
Kakita, A.5
Takahashi, H.6
-
185
-
-
0028843647
-
Editing for an ampa receptor subunit rna in prefrontal cortex and striatum in alzheimer's disease huntington's disease and schizophrenia
-
Akbarian S, Smith MA, Jones EG. Editing for an AMPA receptor subunit RNA in prefrontal cortex and striatum in Alzheimer's disease, Huntington's disease and schizophrenia. Brain Res. 1995; 699: 297-304
-
(1995)
Brain Res
, vol.699
, pp. 297-304
-
-
Akbarian, S.1
Smith, M.A.2
Jones, E.G.3
-
186
-
-
15044346521
-
Deficient rna editing of glur2 and neuronal death in amyotropic lateral sclerosis
-
Kwak S, Kawahara Y. Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis. JMol Med (Berl). 2005; 83: 110-20
-
(2005)
J Mol Med (Berl
, vol.83
, pp. 110-120
-
-
Kwak, S.1
Kawahara, Y.2
-
187
-
-
77953870821
-
TDP-43 pathology in sporadic ALS occurs in motor neurons lacking the RNA editing enzyme ADAR2
-
Aizawa H, Sawada J, Hideyama T, Yamashita T, Katayama T, Hasebe N, et al. TDP-43 pathology in sporadic ALS occurs in motor neurons lacking the RNA editing enzyme ADAR2. Acta Neuropathol. 2010; 120: 75-84
-
(2010)
Acta Neuropathol
, vol.120
, pp. 75-84
-
-
Aizawa, H.1
Sawada, J.2
Hideyama, T.3
Yamashita, T.4
Katayama, T.5
Hasebe, N.6
-
188
-
-
84865190331
-
Co-occurrence of TDP-43 mislocalization with reduced activity of an RNA editing enzyme, ADAR2, in aged mouse motor neurons
-
Hideyama T, Teramoto S, Hachiga K, Yamashita T, Kwak S. Co-occurrence of TDP-43 mislocalization with reduced activity of an RNA editing enzyme, ADAR2, in aged mouse motor neurons. PLoS One. 2012; 7: E43469
-
(2012)
PLoS One
, vol.7
-
-
Hideyama, T.1
Teramoto, S.2
Hachiga, K.3
Yamashita, T.4
Kwak, S.5
-
189
-
-
78651408754
-
Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes
-
Sephton C F, Cenik C, Kucukural A, Dammer E B, Cenik B, Han Y, et al. Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes. JBiol Chem. 2011; 286: 1204-15
-
(2011)
J Biol Chem
, vol.286
, pp. 1204-1215
-
-
Sephton, C.F.1
Cenik, C.2
Kucukural, A.3
Dammer, E.B.4
Cenik, B.5
Han, Y.6
-
190
-
-
84860320548
-
The abnormal processing of TDP-43 is not an upstream event of reduced ADAR2 activity in ALS motor neurons
-
Yamashita T, Hideyama T, Teramoto S, Kwak S. The abnormal processing of TDP-43 is not an upstream event of reduced ADAR2 activity in ALS motor neurons. Neurosci Res. 2012; 73: 153-60
-
(2012)
Neurosci Res
, vol.73
, pp. 153-160
-
-
Yamashita, T.1
Hideyama, T.2
Teramoto, S.3
Kwak, S.4
-
191
-
-
33847317017
-
Redirection of silencing targets by adenosine-To-inosine editing of miRNAs
-
Kawahara Y, Zinshteyn B, Sethupathy P, Iizasa H, Hatzigeorgiou AG, Nishikura K. Redirection of silencing targets by adenosine-To-inosine editing of miRNAs. Science. 2007; 315: 1137-40
-
(2007)
Science
, vol.315
, pp. 1137-1140
-
-
Kawahara, Y.1
Zinshteyn, B.2
Sethupathy, P.3
Iizasa, H.4
Hatzigeorgiou, A.G.5
Nishikura, K.6
-
192
-
-
84863229628
-
Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome
-
Peng Z, Cheng Y, Tan BC, Kang L, Tian Z, Zhu Y, et al. Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol. 2012; 30: 253-60
-
(2012)
Nat Biotechnol
, vol.30
, pp. 253-260
-
-
Peng, Z.1
Cheng, Y.2
Tan, B.C.3
Kang, L.4
Tian, Z.5
Zhu, Y.6
-
193
-
-
84864591239
-
Systematic identification of edited microRNAs in the human brain
-
Alon S, Mor E, Vigneault F, Church GM, Locatelli F, Galeano F, et al. Systematic identification of edited microRNAs in the human brain. Genome Res. 2012; 22: 1533-40
-
(2012)
Genome Res
, vol.22
, pp. 1533-1540
-
-
Alon, S.1
Mor, E.2
Vigneault, F.3
Church, G.M.4
Locatelli, F.5
Galeano, F.6
-
194
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee J J, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007; 9: 654-9
-
(2007)
Nat Cell Biol
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekstrom, K.2
Bossios, A.3
Sjostrand, M.4
Lee, J.J.5
Lotvall, J.O.6
-
195
-
-
66549122028
-
Cell-To-cell signalling via exosomes through esRNA
-
Lotvall J, Valadi H. Cell-To-cell signalling via exosomes through esRNA. Cell Adh Migr. 2007; 1: 156-8
-
(2007)
Cell Adh Migr
, vol.1
, pp. 156-158
-
-
Lotvall, J.1
Valadi, H.2
-
196
-
-
0022894641
-
Accumulation of neurofilaments in a sporadic case of amyotrophic lateral sclerosis
-
Kondo A, Iwaki T, Tateishi J, Kirimoto K, Morimoto T, Oomura I. Accumulation of neurofilaments in a sporadic case of amyotrophic lateral sclerosis. Jpn J Psychiatry Neurol. 1986; 40: 677-84
-
(1986)
J pn J Psychiatry Neurol
, vol.40
, pp. 677-684
-
-
Kondo, A.1
Iwaki, T.2
Tateishi, J.3
Kirimoto, K.4
Morimoto, T.5
Oomura, I.6
-
197
-
-
58049192812
-
Deleterious variants of FIG4, aphosphoinositide phosphatase, in patients with ALS
-
Chow C Y, Landers J E, Bergren S K, Sapp P C, Grant AE, Jones JM, et al. Deleterious variants of FIG4, aphosphoinositide phosphatase, in patients with ALS. Am J Hum Genet. 2009; 84: 85-8
-
(2009)
Am J Hum Genet
, vol.84
, pp. 85-88
-
-
Chow, C.Y.1
Landers, J.E.2
Bergren, S.K.3
Sapp, P.C.4
Grant, A.E.5
Jones, J.M.6
-
198
-
-
33645422711
-
ANG mutations segregate with familial and ' sporadic'amyotrophic lateral sclerosis
-
Greenway M J, Andersen P M, Russ C, Ennis S, Cashman S, Donaghy C, et al. ANG mutations segregate with familial and ' sporadic' amyotrophic lateral sclerosis. Nat Genet. 2006; 38: 411-3
-
(2006)
Nat Genet
, vol.38
, pp. 411-413
-
-
Greenway, M.J.1
Andersen, P.M.2
Russ, C.3
Ennis, S.4
Cashman, S.5
Donaghy, C.6
-
199
-
-
84863507711
-
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
-
Couthouis J, Hart MP, Erion R, King OD, Diaz Z, Nakaya T, et al. Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Hum Mol Genet. 2012; 21: 2899-911
-
(2012)
Hum Mol Genet
, vol.21
, pp. 2899-2911
-
-
Couthouis, J.1
Hart, M.P.2
Erion, R.3
King, O.D.4
Diaz, Z.5
Nakaya, T.6
-
200
-
-
2442658908
-
DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4
-
Chen YZ, Bennett CL, Huynh HM, Blair IP, Puls I, Irobi J, et al. DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4). Am J Hum Genet. 2004; 74: 1128-35
-
(2004)
Am J Hum Genet
, vol.74
, pp. 1128-1135
-
-
Chen, Y.Z.1
Bennett, C.L.2
Huynh, H.M.3
Blair, I.P.4
Puls, I.5
Irobi, J.6
-
201
-
-
52949094629
-
Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis
-
Rutherford N J, Zhang YJ, Baker M, Gass J M, Finch N A, Xu YF, et al. Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis. PLoS Genet. 2008; 4: E1000193
-
(2008)
PLoS Genet
, vol.4
-
-
Rutherford, N.J.1
Zhang, Y.J.2
Baker, M.3
Gass, J.M.4
Finch, N.A.5
Xu, Y.F.6
-
202
-
-
0028001606
-
Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
-
Figlewicz D A, Krizus A, Martinoli M G, Meininger V, Dib M, Rouleau GA, et al. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum Mol Genet. 1994; 3: 1757-61
-
(1994)
Hum Mol Genet
, vol.3
, pp. 1757-1761
-
-
Figlewicz, D.A.1
Krizus, A.2
Martinoli, M.G.3
Meininger, V.4
Dib, M.5
Rouleau, G.A.6
-
203
-
-
8544222694
-
Aframeshift deletion in peripherin gene associated with amyotrophic lateral sclerosis
-
Gros-Louis F, Lariviere R, Gowing G, Laurent S, Camu W, Bouchard JP, et al. Aframeshift deletion in peripherin gene associated with amyotrophic lateral sclerosis. JBiol Chem. 2004; 279: 45951-6
-
(2004)
J Biol Chem
, vol.279
, pp. 45951-45956
-
-
Gros-Louis, F.1
Lariviere, R.2
Gowing, G.3
Laurent, S.4
Camu, W.5
Bouchard, J.P.6
-
204
-
-
33749006845
-
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B
-
Parkinson N, Ince PG, Smith MO, Highley R, Skibinski G, Andersen PM, et al. ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B). Neurology. 2006; 67: 1074-7
-
(2006)
Neurology
, vol.67
, pp. 1074-1077
-
-
Parkinson, N.1
Ince, P.G.2
Smith, M.O.3
Highley, R.4
Skibinski, G.5
Andersen, P.M.6
-
205
-
-
4143084861
-
Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS
-
Munch C, Sedlmeier R, Meyer T, Homberg V, Sperfeld AD, Kurt A, et al. Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS. Neurology. 2004; 63: 724-6
-
(2004)
Neurology
, vol.63
, pp. 724-726
-
-
Munch, C.1
Sedlmeier, R.2
Meyer, T.3
Homberg, V.4
Sperfeld, A.D.5
Kurt, A.6
-
206
-
-
6344257200
-
Amutation in the vesicletrafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
-
Nishimura AL, Mitne-Neto M, Silva H C, Richieri-Costa A, Middleton S, Cascio D, et al. Amutation in the vesicletrafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. Am J Hum Genet. 2004; 75: 822-31
-
(2004)
Am J Hum Genet
, vol.75
, pp. 822-831
-
-
Nishimura, A.L.1
Mitne-Neto, M.2
Silva, H.C.3
Richieri-Costa, A.4
Middleton, S.5
Cascio, D.6
-
207
-
-
80855150639
-
SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis
-
Fecto F, Yan J, Vemula SP, Liu E, Yang Y, Chen W, et al. SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis. Arch Neurol. 2011; 68: 1440-6
-
(2011)
Arch Neurol
, vol.68
, pp. 1440-1446
-
-
Fecto, F.1
Yan, J.2
Vemula, S.P.3
Liu, E.4
Yang, Y.5
Chen, W.6
-
208
-
-
0034785509
-
The gene encoding alsin, aprotein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
-
Yang Y, Hentati A, Deng H X, Dabbagh O, Sasaki T, Hirano M, et al. The gene encoding alsin, aprotein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nat Genet. 2001; 29: 160-5
-
(2001)
Nat Genet
, vol.29
, pp. 160-165
-
-
Yang, Y.1
Hentati, A.2
Deng, H.X.3
Dabbagh, O.4
Sasaki, T.5
Hirano, M.6
-
209
-
-
0034785483
-
Agene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
Hadano S, Hand CK, Osuga H, Yanagisawa Y, Otomo A, Devon RS, et al. Agene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet. 2001; 29: 166-73
-
(2001)
Nat Genet
, vol.29
, pp. 166-173
-
-
Hadano, S.1
Hand, C.K.2
Osuga, H.3
Yanagisawa, Y.4
Otomo, A.5
Devon, R.S.6
-
210
-
-
77952194773
-
Familial amyotrophic lateral sclerosis is associated with a mutation in D-Amino acid oxidase
-
Mitchell J, Paul P, Chen H J, Morris A, Payling M, Falchi M, et al. Familial amyotrophic lateral sclerosis is associated with a mutation in D-Amino acid oxidase. Proc Natl Acad Sci U S A. 2010; 107: 7556-61
-
(2010)
Proc Natl Acad Sci U S.A.
, vol.107
, pp. 7556-7561
-
-
Mitchell, J.1
Paul, P.2
Chen, H.J.3
Morris, A.4
Payling, M.5
Falchi, M.6
-
211
-
-
84868656581
-
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
-
Van Hoecke A, Schoonaert L, Lemmens R, Timmers M, Staats KA, Laird AS, et al. EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nat Med. 2012; 18: 1418-22
-
(2012)
Nat Med
, vol.18
, pp. 1418-1422
-
-
Van Hoecke, A.1
Schoonaert, L.2
Lemmens, R.3
Timmers, M.4
Staats, K.A.5
Laird, A.S.6
-
212
-
-
77249126425
-
Spatacsin mutations cause autosomal recessive juvenile amyotrophic lateral sclerosis
-
Orlacchio A, Babalini C, Borreca A, Patrono C, Massa R, Basaran S, et al. SPATACSIN mutations cause autosomal recessive juvenile amyotrophic lateral sclerosis. Brain. 2010; 133: 591-8
-
(2010)
Brain
, vol.133
, pp. 591-598
-
-
Orlacchio, A.1
Babalini, C.2
Borreca, A.3
Patrono, C.4
Massa, R.5
Basaran, S.6
-
213
-
-
18244393223
-
Anovel locus for familial amyotrophic lateral sclerosis, on chromosome 18q
-
Hand CK, Khoris J, Salachas F, Gros-Louis F, Lopes AA, Mayeux-Portas V, et al. Anovel locus for familial amyotrophic lateral sclerosis, on chromosome 18q. Am J Hum Genet. 2002; 70: 251-6
-
(2002)
Am J Hum Genet
, vol.70
, pp. 251-256
-
-
Hand, C.K.1
Khoris, J.2
Salachas, F.3
Gros-Louis, F.4
Lopes, A.A.5
Mayeux-Portas, V.6
-
214
-
-
0032414948
-
Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers
-
Hentati A, Ouahchi K, Pericak-Vance MA, Nijhawan D, Ahmad A, Yang Y, et al. Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers. Neurogenetics. 1998; 2: 55-60
-
(1998)
Neurogenetics
, vol.2
, pp. 55-60
-
-
Hentati, A.1
Ouahchi, K.2
Pericak-Vance, M.A.3
Nijhawan, D.4
Ahmad, A.5
Yang, Y.6
-
215
-
-
0041664059
-
Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis
-
Sapp P C, Hosler B A, McKenna-Yasek D, Chin W, Gann A, Genise H, et al. Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis. Am J Hum Genet. 2003; 73: 397-403
-
(2003)
Am J Hum Genet
, vol.73
, pp. 397-403
-
-
Sapp, P.C.1
Hosler, B.A.2
McKenna-Yasek, D.3
Chin, W.4
Gann, A.5
Genise, H.6
|