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Volumn 284, Issue 5423, 1999, Pages 2174-2177

Regulation of transcription by a protein methyltransferase

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; HORMONE RECEPTOR; PROTEIN KINASE P60; PROTEIN METHYLTRANSFERASE;

EID: 0033603396     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.284.5423.2174     Document Type: Article
Times cited : (1035)

References (35)
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    • 1121-1462) in vector pGBT9 (Clontech), which has a trp 1 marker gene. Further screening of a lambda phage library of mouse 11-day embryo cDNA clones (Stratagene) identified additional 5′ sequences and allowed construction of a putative full-length coding region (608 codons) for CARM1 (GenBank accession number AF117887).
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    • C (amino acids 1122 to 1462) an Eco Rl-Sal I fragment was inserted. The CARM1 VLD-to-AAA mutation was engineered with the Promega Gene Editor Kit
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    • note
    • We thank the following investigators for providing cDNA clones: H. R. Herschman (University of California, Los Angeles) for PRMT1, R. M. Evans (Salk institute, La Jolla, CA) for ACTR, M.-J. Tsai and B. W. O'Malley (Baylor College of Medicine, Houston, TX) for SRC-1a, and A. O. Brinkmann (Erasmus University, Rotterdam, Netherlands) for androgen receptor. We thank S. Subramanian, L Yang, and R. Widelitz for technical assistance and D. Johnson and R Maxson (University of Southern California) for critical comments on the manuscript. Supported by USPHS grants DK43093 (M.R.S.) and NS17269 (D.W.A.) from the NIH and by a predoctoral traineeship from the University of California Breast Cancer Research Program (H.M.) and a predoctoral traineeship from grant AG00093 (S.S.K.) from the National Institutes of Health.


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