Retroviruses and amyotrophic lateral sclerosis

Antiviral Research

Volumn 99, Issue 2, 2013, Pages 180-187

  Alfahad, Tariq ^a   Nath, Avindra ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Amyotropic lateral sclerosis; Human endogenous retrovirus; Human immunodeficiency virus; Reverse transcriptase; Transposons

Indexed keywords

RNA DIRECTED DNA POLYMERASE;

AMYOTROPHIC LATERAL SCLEROSIS; CENTRAL NERVOUS SYSTEM; ENZYME ACTIVITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS 1 INFECTION; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; REVIEW; SIMIAN FOAMY VIRUS; VIRUS INFECTION; VIRUS LOAD;

HUMAN ENDOGENOUS RETROVIRUS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN T-LYMPHOTROPIC VIRUS 1;

EID: 84879232244     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.05.006     Document Type: Review

References (68)

1. Almeida V., Mestre T., De Carvalho M. Pseudobulbar syndrome in two patients with human immunodeficiency virus infection. Amyotrophic Lateral Scler. 2010, 11(1-2):220-222.
2. Andrews W.D., Al-Chalabi A., Garson J.A. Lack of evidence for HTLV tax-rex DNA in motor neurone disease. J. Neurol. Sci. 1997, 153(1):86-90.
3. Andrews W.D., Tuke P.W., Al-Chalabi A., Gaudin P., Ijaz S., Parton M.J., Garson J.A. Detection of reverse transcriptase activity in the serum of patients with motor neurone disease. J. med. virol. 2000, 61(4):527-532.
4. Arimura Hashiguchi K., Higuchi I., Osame M. HTLV-I-associated myelopathy (HAM) presenting with ALS-like features 1989, HTLV-I and the nervous system. Alan R. Liss, New York, 367-370.
5. Balada E., Vilardell-Tarrés M., Ordi-Ros J. Implication of human endogenous retroviruses in the development of autoimmune diseases. Int. Rev. Immunol. 2010, 29(4):351-370.
6. Berger J.R., Espinosa P.S., Kissel J. Brachial amyotrophic diplegia in a patient with human immunodeficiency virus infection: widening the spectrum of motor neuron diseases occurring with the human immunodeficiency virus. Arch. Neurol. 2005, 62(5):817.
7. Brooks B.R., Miller R.G., Swash M., Munsat T.L. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2000, 1(5):293-299.
8. Calza L., Manfredi R., Freo E., Farneti B., Tampellini L., Chiodo F. Transient reversal of HIV-associated motor neuron disease following the introduction of highly active antiretroviral therapy. J. chemother. 2004, 16(1):98-101.
9. Casado I., Gomez M., Carmona C., Garcia-Castanon I., Martin C., Sanchez J.F. Motor neuron disease and HIV. Rev. Neurol. 1997, 25:552-554.
10. Castro N.M., Rodrigues W., Freitas D.M., Muniz A., Oliveira P., Carvalho E.M. Urinary symptoms associated with human T-cell lymphotropic virus type I infection: evidence of urinary manifestations in large group of HTLV-I carriers. Urology 2007, 69(5):813-818.
11. Christensen T. Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses. Rev. Med. Virol. 2005, 15(3):179-211.
12. Cosenza M.A., Zhao M., Si Q., Lee S.C. Human brain parenchymal microglia express CD14 and CD45 and are productively infected by HIV-1 in HIV-1 encephalitis. Brain Pathol. 2002, 12(4):442-455.
13. DeJesus-Hernandez M., Mackenzie I.R., Boeve B.F., Boxer A.L., Baker M., Rutherford N.J., Rademakers R. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011, 72(2):245-256.
14. Delelis O., Lehmann-Che J., Saïb A. Foamy viruses-a world apart. Curr. Opin. Microbiol. 2004, 7(4):400-406.
15. Douville R., Liu J., Rothstein J., Nath A. Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis. Ann. Neurol. 2011, 69(1):141-151.
16. Evans B.K., Gore I., Harrell L.E., Arnold T., Oh S.J. HTLV-I-associated myelopathy and polymyositis in a US native. Neurology 1989, 39(12):1572.
17. Ferraiuolo L., Kirby J., Grierson A.J., Sendtner M., Shaw P.J. Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis. Nat. Rev. Neurol. 2011, 7(11):616-630.
18. Galassi G., Gentilini M., Ferrari S., Ficarra G., Zonari P., Mongiardo N., Di Rienzo B. Motor neuron disease and HIV-1 infection in a 30-year-old HIV-positive heroin abuser: a causal relationship?. Clin. Neuropathol. 1998, 17(3):131.
19. Hadlock K.G., Miller R.G., Jin X., Yu S., Reis J., Mass J., Gelinas D.F., Zhang J., McGrath M.S. Elevated rates of antibody reactivity to HML-2/HERV-K but not other endogenous retroviruses in ALS. Amyotroph Lateral Scler. Other Motor Neuron Disord. 2004, 5(Suppl. 2):63.
20. Hoffman P.M., Festoff B.W., Giron L.T., Hollenbeck L.C., Garruto R.M., Ruscetti F.W. Isolation of LAV/HTLV-III from a patient with amyotrophic lateral sclerosis. N. Engl. J. Med. 1985, 313(5):324.
21. Huang P.P., Chin R., Song S., Lasoff S. Lower motor neuron dysfunction associated with human immunodeficiency virus infection. Arch. Neurol. 1993, 50(12):1328.
22. Jubelt B., Berger J.R. Does viral disease underlie ALS? Lessons from the AIDS pandemic. Neurology 2001, 57(6):945-946.
23. Karlsson H., Schröder J., Bachmann S., Bottmer C., Yolken R.H. HERV-W-related RNA detected in plasma from individuals with recent-onset schizophrenia or schizoaffective disorder. Mol. Psychiatry 2003, 9(1):12-13.
24. Kuroda Y., Sugihara H. Autopsy report of HTLV-I-associated myelopathy presenting with ALS-like manifestations. J. Neurol. Sci. 1991, 106(2):199-205.
25. Lander E.S., Linton L.M., Birren B., Nusbaum C., Zody M.C., Baldwin J., Grafham D. Initial sequencing and analysis of the human genome. Nature 2001, 409(6822):860-921.
26. Lattante S., Conte A., Zollino M., Luigetti M., Del Grande A., Marangi G., Sabatelli M. Contribution of major amyotrophic lateral sclerosis genes to the etiology of sporadic disease. Neurology 2012, 79(1):66-72.
27. Li W., Jin Y., Prazak L., Hammell M., Dubnau J. Transposable elements in TDP-43-mediated neurodegenerative disorders. PLoS ONE 2012, 7(9):e44099.
28. Logroscino G., Traynor B.J., Hardiman O., Chiò A., Mitchell D., Swingler R.J., Beghi E. Incidence of amyotrophic lateral sclerosis in Europe. J. Neurol. Neurosurg. Psychiatry 2010, 81(4):385-390.
29. MacGowan D.J.L., Scelsa S.N., Waldron M. An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy. Neurology 2001, 57(6):1094-1097.
30. Matsuzaki T., Nakagawa M., Nagai M., Nobuhara Y., Usuku K., Higuchi I., Takahashi K., Moritoyo T., Arimura K., Izumo S., Akiba S., Osame M. HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) with amyotrophic lateral sclerosis-like manifestations. J. neurovirol. 2000, 6(6):544-548.
31. McCormick A.L., Brown R.H., Cudkowicz M.E., Al-Chalabi A., Garson J.A. Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate. Neurology 2008, 70(4):278-283.
32. Moulignier A., Moulonguet A., Pialoux G., Rozenbaum W. Reversible ALS-like disorder in HIV infection. Neurology 2001, 57(6):995-1001.
33. Mueller N. The epidemiology of HTLV-I infection. Cancer Causes Control 1991, 2(1):37-52.
34. Nishio M., Koizumi K., Moriwaka F., Koike T., Sawada K. Reversal of HIV-associated motor neuron syndrome after highly active antiretroviral therapy. J. Neurol. 2001, 248(3):233-234.
35. Norris F.J. Current status of the search for virus in amyotrophic lateral sclerosis (ALS). Neuro. Neurocir. Psiquiatr. 1977, 18(2-3 Suppl.):443-454.
36. Oluwole O.S.A., Conradi S., Kristensson K., Karlsson H. Human endogenous retrovirus W and motor neurone disease. Ann. of tbadan Postgrad. Med. 2004, 2(2):39-42.
37. Oluwole O.S.A., Yao Y., Conradi S., Kristensson K., Karlsson H. Elevated levels of transcripts encoding a human retroviral envelope protein (syncytin) in muscles from patients with motor neuron disease. Amyotroph Lateral Scler. 2007, 8(2):67-72.
38. Orsini, M., RG. de Freitas, M., G Silva, J., P Sohler, M., T., Nakagawa, M., Nagai, M., Nobuhara, Y., Usuku, k., Higuchi, I., Takahashi, K., Moritoyo, T., Arimura, K., Izumo, S., Akiba, S., Osame, M., HM Reis, C., M da Silva Catharino, A., B Oliveira, A., Machado, S., E Nardi, A., Salem, P., Sztajnbok, F., AA Leite, M., Nascimento, C., Davidovich, E., H de Gobbi Porto, F., W Cruz, M., L.S de Menezes, S., Arias-Carrion, O., 2012. Motor Neuron Disease and Acquired Axonal Neuropathy Association in HIV Infection: Case Report and Update. Curr. HIV Res. 10 (8), 694-699.
39. Pearl D., Noursadeghi M., Manji H., Edwards S., Miller R. Lower motor neuron syndrome and HIV infection. Sex. Transm. Infect. 2003, 79(4):351.
40. Reed D., Labarthe D., Chen K.M., Stallones R. A cohort study of amyotrophic lateral sclerosis and parkinsonism-dementia on Guam and Rota. Am. J. Epidemiol. 1987, 125(1):92-100.
41. Renton A.E., Majounie E., Waite A., Simón-Sánchez J., Rollinson S., Gibbs J.R., Sulkava R. A Hexanucleotide Repeat Expansion in C9ORF72 is the cause of chromosome 9p21-Linked ALS-FTD. Neuron 2011, 72(2):257-268.
42. Romanish M.T., Cohen C.J., Mager D.L. Potential mechanisms of endogenous retroviral-mediated genomic instability in human cancer. Seminars in Cancer Biology 2010, vol. 20:246-253. Academic Press, (No. 4).
43. Rösener M., Hahn H., Kranz M., Heeney J., Rethwilm A. Absence of serological evidence for foamy virus infection in patients with amyotrophic lateral sclerosis. J. Med. Virol. 1998, 48(3):222-226.
44. Sahashi, K., Ibi, T., Tuchiya, I., Morishima, T., Takahashi, A., 1989. HTLV-I associated encephalo-myelopathy resembling ALS with concurrence of acute promyelocytic leukemia in a member of the relatives. Rinshō shinkeigaku 29 (1), 98.
45. Sastre-Garriga J., Tintoré M., Raguer N., Ruiz I., Montalban X., Codina A. Lower motor neuron disease in a HIV-2 infected woman. J. Neurol. 2000, 2000(247):718-719.
46. Scelsa S.N., MacGowan D.J.L., Mitsumoto H., Imperato T., LeValley A.J., Liu M.H., Kim M.Y. A pilot, double-blind, placebo-controlled trial of indinavir in patients with ALS. Neurology 2005, 64(7):1298-1300.
47. Sher J.H., Wrzolek M.A., Shmuter Z.B. Motor neuron disease associated with AIDS. J. Neuropathol. Exp. Neurol. 1988, 47:303.
48. Silva M.T.T., Leite A.C.C., Alamy A.H., Chimelli L., Andrada-Serpa M.J., Araújo A.Q.C. ALS syndrome in HTLV-I infection. Neurology 2005, 65(8):1332-1333.
49. Simpson D.M., Morgello S., Citak K., Corbo M., Latov N. Motor neuron disease associated with HIV-1 and anti-asialo GM1 antibody. Muscle Nerve 1994, 17:1091.
50. Simpson D., Estanislao L., Evans S., McArthur J., Marcus K., Truffa M., Clifford D. HIV-associated neuromuscular weakness syndrome. AIDS 2004, 18(10):1403-1412.
51. Sinha S., Mathews T., Arunodaya G.R., Siddappa N.B., Ranga U., Desai A., Taly A.B. HIV-1 clade-C-associated "ALS"-like disorder: first report from India. J. Neurol. Sci. 2004, 224(1):97-100.
52. Steele A.J., Al-Chalabi A., Ferrante K., Cudkowicz M.E., Brown R.H., Garson J.A. Detection of serum reverse transcriptase activity in patients with ALS and unaffected blood relatives. Neurology 2005, 64(3):454-458.
53. Temin H.M., Mizutani S. A DNA-depenent DNA polymerase and a DNA endonuclease in virions of Rous sarcoma virus. Nature 1970, 226(5252):1211-1213.
54. Urnovitz H.B., Murphy W.H. Human endogenous retroviruses: nature, occurrence, and clinical implications in human disease. Clin. Microbiol. Rev. 1996, 9(1):72-99.
55. Verma A., Berger J.R. ALS syndrome in patients with HIV-1 infection. J. Neurol. Sci. 2006, 240(1):59-64.
56. Verma A., Mishra S. Spectrum of motor neuron diseases with HIV-1 infection. Ann. Indian Acad. Neurol. 2006, 9(2):103-109.
57. Verma R.K., Ziegler D.K., Kepes J.J. HIV-related neuromuscular syndrome simulating motor neuron disease. Neurology 1990, 40(3 Part 1):544-545.
58. Vernant J.C., Buisson G., Bellance R., Francois M.A., Madkaud O., Zavaro O. Pseudo-amyotrophic lateral sclerosis, peripheral neuropathy and chronic polyradiculoneuritis in patients with HTLV-I-associated paraplegias 1989, HTLV-I and the nervous system. Alan R. Liss, New York, 361-365.
59. Viola M.V., Frazier M., White L., Brody J., Spiegelman S. RNA-instructed DNA polymerase activity in a cytoplasmic particulate fraction in brains from Guamanian patients. J. Exp. Med. 1975, 142(2):483-494.
60. von Giesen H.J., Kaiser R., Koller H., Wetzel K., Arendt G. Reversible ALS-like disorder in HIV infection. An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy. Neurology 2002, 59:474.
61. Westarp M.E., Kornhuber H., Rossler J. Human spumaretrovirus antibodies in amyotrophic lateral sclerosis. Neurol. Psychiatry Brain Res. 1992, 1:1-4.
62. Westarp M.E., Westphal K.P., Clausen J., Rasmussen H.B., Hoff-Jorgensen R., Föhring B., Kornhuber H.H. Retroviral interference with neuronotrophic signaling in human motor neuron disease?. Clin. Physiol. Biochem. 1993, 10(1):1.
63. Westarp M.E., Bartmann P., Hoff-Jorgensen R., Clausen J., Rasmussen R., Kornhuber H.H. Amyotrophe Lateralsklerose-Hinweise fur eine erhohte antiretrovirale Seroreaktivitat ohne augenfdlige Epidemiologie. Nervenarzt 1993, 64:384-389.
64. Westarp M.E., Bartmann P., Rössler J., Geiger E., Westphal K.P., Schreiber H., Kornhuber H.H. Antiretroviral therapy in sporadic adult amyotrophic lateral sclerosis. Neuroreport 1993, 4(6):819.
65. Westarp M.E., Fuchs D., Bartmann P., Hoff-Jörgensen R., Clausen J., Wachter H., Kornhuber H.H. Amyotrophic lateral sclerosis an enigmatic disease with B-cellular and anti-retroviral immune responses. Eur. J. Med. 1993, 2(6):327.
66. Westarp M.E., Föhring B., Rasmussen H., Schraff S., Mertens T., Kornhuber H.H. Retroviral synthetic peptide serum antibodies in human sporadic amyotrophic lateral sclerosis. Peptides 1994, 15(2):207-214.
67. Yamamoto S., Folks T.M., Heneine W. Highly sensitive qualitative and quantitative detection of reverse transcriptase activity: optimization, validation, and comparative analysis with other detection systems. J. Virol. Methods 1996, 61(1):135-143.
68. Zoccolella S., Carbonara S., Minerva D., Palagano G., Bruno F., Ferrannini E., Lamberti P. A case of concomitant amyotrophic lateral sclerosis and HIV infection. Eur. J. Neurol. 2002, 9(2):180-182.