FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment

EMBO Journal

Volumn 31, Issue 24, 2012, Pages 4502-4510

  Morlando, Mariangela ^a   Dini Modigliani, Stefano ^a   Torrelli, Giulia ^a   Rosa, Alessandro ^a   Di Carlo, Valerio ^a   Caffarelli, Elisa ^b   Bozzoni, Irene ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

ALS; chromatin immunoprecipitation; Drosha; FUS TLS; microRNA

Indexed keywords

DROSHA PROTEIN; FUSED IN SARCOMA PROTEIN; MICRORNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BIOGENESIS; CELL ACTIVITY; CELL DIFFERENTIATION; CELL FUNCTION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; NERVE CELL; PRIORITY JOURNAL; PROTEIN BINDING; RNA TRANSCRIPTION; SYNAPTOGENESIS; TRANSCRIPTION INITIATION SITE;

BLOTTING, WESTERN; CELL LINE, TUMOR; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; IMMUNOPRECIPITATION; MICRORNAS; NEURONS; OLIGONUCLEOTIDES; PLASMIDS; REAL-TIME POLYMERASE CHAIN REACTION; RIBONUCLEASE III; RNA-BINDING PROTEIN FUS; SYNAPSES;

EID: 84871002507     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.319     Document Type: Article

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