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Volumn 7, Issue 9, 2012, Pages

Gene Expression Responses to FUS, EWS, and TAF15 Reduction and Stress Granule Sequestration Analyses Identifies FET-Protein Non-Redundant Functions

Author keywords

[No Author keywords available]

Indexed keywords

FUSED IN SARCOMA PROTEIN; MESSENGER RNA; NUCLEIC ACID BINDING PROTEIN; PROTEIN FET; PROTEIN TAF15; RNA BINDING PROTEIN EWS; TATA BINDING PROTEIN ASSOCIATED FACTOR; UNCLASSIFIED DRUG;

EID: 84866671948     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046251     Document Type: Article
Times cited : (36)

References (60)
  • 1
    • 0029812470 scopus 로고    scopus 로고
    • hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II
    • Bertolotti A, Lutz Y, Heard DJ, Chambon P, Tora L, (1996) hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II. EMBO J 15: 5022-5031.
    • (1996) EMBO J , vol.15 , pp. 5022-5031
    • Bertolotti, A.1    Lutz, Y.2    Heard, D.J.3    Chambon, P.4    Tora, L.5
  • 2
    • 0032561520 scopus 로고    scopus 로고
    • Genomic structure of the human RBP56/hTAFII68 and FUS/TLS genes
    • Morohoshi F, Ootsuka Y, Arai K, Ichikawa H, Mitani S, et al. (1998) Genomic structure of the human RBP56/hTAFII68 and FUS/TLS genes. Gene 221: 191-198.
    • (1998) Gene , vol.221 , pp. 191-198
    • Morohoshi, F.1    Ootsuka, Y.2    Arai, K.3    Ichikawa, H.4    Mitani, S.5
  • 3
    • 0033598946 scopus 로고    scopus 로고
    • The N-terminal domain of human TAFII68 displays transactivation and oncogenic properties
    • Bertolotti A, Bell B, Tora L, (1999) The N-terminal domain of human TAFII68 displays transactivation and oncogenic properties. Oncogene 18: 8000-8010.
    • (1999) Oncogene , vol.18 , pp. 8000-8010
    • Bertolotti, A.1    Bell, B.2    Tora, L.3
  • 4
    • 0035794162 scopus 로고    scopus 로고
    • Identification of an RNA binding specificity for the potential splicing factor TLS
    • Lerga A, Hallier M, Delva L, Orvain C, Gallais I, et al. (2001) Identification of an RNA binding specificity for the potential splicing factor TLS. J Biol Chem 276: 6807-6816.
    • (2001) J Biol Chem , vol.276 , pp. 6807-6816
    • Lerga, A.1    Hallier, M.2    Delva, L.3    Orvain, C.4    Gallais, I.5
  • 5
    • 79952317624 scopus 로고    scopus 로고
    • Characterization of a Family of RanBP2-Type Zinc Fingers that Can Recognize Single-Stranded RNA
    • Nguyen CD, Mansfield RE, Leung W, Vaz PM, Loughlin FE, et al. (2011) Characterization of a Family of RanBP2-Type Zinc Fingers that Can Recognize Single-Stranded RNA. J Mol Biol 407: 273-283.
    • (2011) J Mol Biol , vol.407 , pp. 273-283
    • Nguyen, C.D.1    Mansfield, R.E.2    Leung, W.3    Vaz, P.M.4    Loughlin, F.E.5
  • 6
    • 0030746523 scopus 로고    scopus 로고
    • TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling
    • Zinszner H, Sok J, Immanuel D, Yin Y, Ron D, (1997) TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling. J Cell Sci 110 (Pt 15): 1741-1750.
    • (1997) J Cell Sci , vol.110 , Issue.Pt 15 , pp. 1741-1750
    • Zinszner, H.1    Sok, J.2    Immanuel, D.3    Yin, Y.4    Ron, D.5
  • 7
    • 0028074607 scopus 로고
    • The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains
    • Ohno T, Ouchida M, Lee L, Gatalica Z, Rao VN, et al. (1994) The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains. Oncogene 9: 3087-3097.
    • (1994) Oncogene , vol.9 , pp. 3087-3097
    • Ohno, T.1    Ouchida, M.2    Lee, L.3    Gatalica, Z.4    Rao, V.N.5
  • 8
    • 0031935157 scopus 로고    scopus 로고
    • EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes
    • Bertolotti A, Melot T, Acker J, Vigneron M, Delattre O, et al. (1998) EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes. Mol Cell Biol 18: 1489-1497.
    • (1998) Mol Cell Biol , vol.18 , pp. 1489-1497
    • Bertolotti, A.1    Melot, T.2    Acker, J.3    Vigneron, M.4    Delattre, O.5
  • 9
    • 0344407006 scopus 로고    scopus 로고
    • Proto-oncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins
    • Meissner M, Lopato S, Gotzmann J, Sauermann G, Barta A, (2003) Proto-oncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins. Exp Cell Res 283: 184-195.
    • (2003) Exp Cell Res , vol.283 , pp. 184-195
    • Meissner, M.1    Lopato, S.2    Gotzmann, J.3    Sauermann, G.4    Barta, A.5
  • 10
    • 0027970712 scopus 로고
    • A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP
    • Zinszner H, Albalat R, Ron D, (1994) A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP. Genes Dev 8: 2513-2526.
    • (1994) Genes Dev , vol.8 , pp. 2513-2526
    • Zinszner, H.1    Albalat, R.2    Ron, D.3
  • 12
    • 36048958883 scopus 로고    scopus 로고
    • Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins
    • Shiohama A, Sasaki T, Noda S, Minoshima S, Shimizu N, (2007) Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins. Exp Cell Res 313: 4196-4207.
    • (2007) Exp Cell Res , vol.313 , pp. 4196-4207
    • Shiohama, A.1    Sasaki, T.2    Noda, S.3    Minoshima, S.4    Shimizu, N.5
  • 13
    • 46649093597 scopus 로고    scopus 로고
    • Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription
    • Wang X, Arai S, Song X, Reichart D, Du K, et al. (2008) Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature 454: 126-130.
    • (2008) Nature , vol.454 , pp. 126-130
    • Wang, X.1    Arai, S.2    Song, X.3    Reichart, D.4    Du, K.5
  • 14
    • 48249083430 scopus 로고    scopus 로고
    • The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
    • Andersson MK, Stahlberg A, Arvidsson Y, Olofsson A, Semb H, et al. (2008) The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response. BMC Cell Biol 9: 37.
    • (2008) BMC Cell Biol , vol.9 , pp. 37
    • Andersson, M.K.1    Stahlberg, A.2    Arvidsson, Y.3    Olofsson, A.4    Semb, H.5
  • 15
    • 63049100536 scopus 로고    scopus 로고
    • PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function
    • Jobert L, Argentini M, Tora L, (2009) PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function. Exp Cell Res 315: 1273-1286.
    • (2009) Exp Cell Res , vol.315 , pp. 1273-1286
    • Jobert, L.1    Argentini, M.2    Tora, L.3
  • 16
    • 0035378344 scopus 로고    scopus 로고
    • Exposure on cell surface and extensive arginine methylation of ewing sarcoma (EWS) protein
    • Belyanskaya LL, Gehrig PM, Gehring H, (2001) Exposure on cell surface and extensive arginine methylation of ewing sarcoma (EWS) protein. J Biol Chem 276: 18681-18687.
    • (2001) J Biol Chem , vol.276 , pp. 18681-18687
    • Belyanskaya, L.L.1    Gehrig, P.M.2    Gehring, H.3
  • 17
    • 80053646130 scopus 로고    scopus 로고
    • Nuclear localization sequence of FUS and induction of stress granules by ALS mutants
    • Gal J, Zhang J, Kwinter DM, Zhai J, Jia H, et al. (2011) Nuclear localization sequence of FUS and induction of stress granules by ALS mutants. Neurobiol Aging 32: e27-40.
    • (2011) Neurobiol Aging , vol.32
    • Gal, J.1    Zhang, J.2    Kwinter, D.M.3    Zhai, J.4    Jia, H.5
  • 18
    • 77955792022 scopus 로고    scopus 로고
    • ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
    • Dormann D, Rodde R, Edbauer D, Bentmann E, Fischer I, et al. (2010) ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import. EMBO J 29: 2841-2857.
    • (2010) EMBO J , vol.29 , pp. 2841-2857
    • Dormann, D.1    Rodde, R.2    Edbauer, D.3    Bentmann, E.4    Fischer, I.5
  • 19
    • 4143088149 scopus 로고    scopus 로고
    • Kinesin transports RNA: isolation and characterization of an RNA-transporting granule
    • Kanai Y, Dohmae N, Hirokawa N, (2004) Kinesin transports RNA: isolation and characterization of an RNA-transporting granule. Neuron 43: 513-525.
    • (2004) Neuron , vol.43 , pp. 513-525
    • Kanai, Y.1    Dohmae, N.2    Hirokawa, N.3
  • 20
    • 30544448358 scopus 로고    scopus 로고
    • TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines
    • Fujii R, Takumi T, (2005) TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines. J Cell Sci 118: 5755-5765.
    • (2005) J Cell Sci , vol.118 , pp. 5755-5765
    • Fujii, R.1    Takumi, T.2
  • 21
    • 15744378126 scopus 로고    scopus 로고
    • The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology
    • Fujii R, Okabe S, Urushido T, Inoue K, Yoshimura A, et al. (2005) The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology. Curr Biol 15: 587-593.
    • (2005) Curr Biol , vol.15 , pp. 587-593
    • Fujii, R.1    Okabe, S.2    Urushido, T.3    Inoue, K.4    Yoshimura, A.5
  • 22
    • 84655167803 scopus 로고    scopus 로고
    • Characterization and expression analysis in the developing embryonic brain of the porcine FET family: FUS, EWS, and TAF15
    • Blechingberg J, Holm IE, Nielsen AL, (2012) Characterization and expression analysis in the developing embryonic brain of the porcine FET family: FUS, EWS, and TAF15. Gene 493: 27-35.
    • (2012) Gene , vol.493 , pp. 27-35
    • Blechingberg, J.1    Holm, I.E.2    Nielsen, A.L.3
  • 23
    • 34548446433 scopus 로고    scopus 로고
    • Sarcomas: genetics, signalling, and cellular origins. Part 1: The fellowship of TET
    • Riggi N, Cironi L, Suva ML, Stamenkovic I, (2007) Sarcomas: genetics, signalling, and cellular origins. Part 1: The fellowship of TET. J Pathol 213: 4-20.
    • (2007) J Pathol , vol.213 , pp. 4-20
    • Riggi, N.1    Cironi, L.2    Suva, M.L.3    Stamenkovic, I.4
  • 24
    • 77449136874 scopus 로고    scopus 로고
    • The TET family of proteins: functions and roles in disease
    • Tan AY, Manley JL, (2009) The TET family of proteins: functions and roles in disease. J Mol Cell Biol 1: 82-92.
    • (2009) J Mol Cell Biol , vol.1 , pp. 82-92
    • Tan, A.Y.1    Manley, J.L.2
  • 26
    • 79551547450 scopus 로고    scopus 로고
    • FUS/TLS Is a Novel Mediator of Androgen-Dependent Cell-Cycle Progression and Prostate Cancer Growth
    • Brooke GN, Culley RL, Dart DA, Mann DJ, Gaughan L, et al. (2011) FUS/TLS Is a Novel Mediator of Androgen-Dependent Cell-Cycle Progression and Prostate Cancer Growth. Cancer Res 71: 914-924.
    • (2011) Cancer Res , vol.71 , pp. 914-924
    • Brooke, G.N.1    Culley, R.L.2    Dart, D.A.3    Mann, D.J.4    Gaughan, L.5
  • 27
    • 61349162349 scopus 로고    scopus 로고
    • Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
    • Vance C, Rogelj B, Hortobagyi T, De Vos KJ, Nishimura AL, et al. (2009) Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science 323: 1208-1211.
    • (2009) Science , vol.323 , pp. 1208-1211
    • Vance, C.1    Rogelj, B.2    Hortobagyi, T.3    de Vos, K.J.4    Nishimura, A.L.5
  • 29
    • 61349156118 scopus 로고    scopus 로고
    • Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
    • Kwiatkowski TJ Jr, Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, et al. (2009) Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 323: 1205-1208.
    • (2009) Science , vol.323 , pp. 1205-1208
    • Kwiatkowski Jr., T.J.1    Bosco, D.A.2    Leclerc, A.L.3    Tamrazian, E.4    Vanderburg, C.R.5
  • 30
    • 84863507711 scopus 로고    scopus 로고
    • Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
    • Couthouis J, Hart MP, Erion R, King OD, Diaz Z, et al. (2012) Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Hum Mol Genet 21: 2899-2911.
    • (2012) Hum Mol Genet , vol.21 , pp. 2899-2911
    • Couthouis, J.1    Hart, M.P.2    Erion, R.3    King, O.D.4    Diaz, Z.5
  • 31
    • 69549103145 scopus 로고    scopus 로고
    • Recent advances in our understanding of neurodegeneration
    • Jellinger KA, (2009) Recent advances in our understanding of neurodegeneration. J Neural Transm 116: 1111-1162.
    • (2009) J Neural Transm , vol.116 , pp. 1111-1162
    • Jellinger, K.A.1
  • 34
    • 77957867303 scopus 로고    scopus 로고
    • Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules
    • Bosco DA, Lemay N, Ko HK, Zhou H, Burke C, et al. (2010) Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules. Hum Mol Genet 19: 4160-4175.
    • (2010) Hum Mol Genet , vol.19 , pp. 4160-4175
    • Bosco, D.A.1    Lemay, N.2    Ko, H.K.3    Zhou, H.4    Burke, C.5
  • 35
    • 77952932485 scopus 로고    scopus 로고
    • FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis
    • Deng HX, Zhai H, Bigio EH, Yan J, Fecto F, et al. (2010) FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis. Ann Neurol 67: 739-748.
    • (2010) Ann Neurol , vol.67 , pp. 739-748
    • Deng, H.X.1    Zhai, H.2    Bigio, E.H.3    Yan, J.4    Fecto, F.5
  • 36
    • 70350673956 scopus 로고    scopus 로고
    • A new subtype of frontotemporal lobar degeneration with FUS pathology
    • Neumann M, Rademakers R, Roeber S, Baker M, Kretzschmar HA, et al. (2009) A new subtype of frontotemporal lobar degeneration with FUS pathology. Brain 132: 2922-2931.
    • (2009) Brain , vol.132 , pp. 2922-2931
    • Neumann, M.1    Rademakers, R.2    Roeber, S.3    Baker, M.4    Kretzschmar, H.A.5
  • 37
    • 80052959701 scopus 로고    scopus 로고
    • FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations
    • Neumann M, Bentmann E, Dormann D, Jawaid A, DeJesus-Hernandez M, et al. (2011) FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations. Brain 134: 2595-2609.
    • (2011) Brain , vol.134 , pp. 2595-2609
    • Neumann, M.1    Bentmann, E.2    Dormann, D.3    Jawaid, A.4    DeJesus-Hernandez, M.5
  • 38
    • 77950788517 scopus 로고    scopus 로고
    • FUS-immunoreactive intranuclear inclusions in neurodegenerative disease
    • Woulfe J, Gray DA, Mackenzie IR, (2010) FUS-immunoreactive intranuclear inclusions in neurodegenerative disease. Brain Pathol 20: 589-597.
    • (2010) Brain Pathol , vol.20 , pp. 589-597
    • Woulfe, J.1    Gray, D.A.2    Mackenzie, I.R.3
  • 39
    • 44449177217 scopus 로고    scopus 로고
    • RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells
    • Doi H, Okamura K, Bauer PO, Furukawa Y, Shimizu H, et al. (2008) RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells. J Biol Chem 283: 6489-6500.
    • (2008) J Biol Chem , vol.283 , pp. 6489-6500
    • Doi, H.1    Okamura, K.2    Bauer, P.O.3    Furukawa, Y.4    Shimizu, H.5
  • 40
    • 73249135817 scopus 로고    scopus 로고
    • The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases
    • Doi H, Koyano S, Suzuki Y, Nukina N, Kuroiwa Y, (2010) The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases. Neurosci Res 66: 131-133.
    • (2010) Neurosci Res , vol.66 , pp. 131-133
    • Doi, H.1    Koyano, S.2    Suzuki, Y.3    Nukina, N.4    Kuroiwa, Y.5
  • 41
    • 0017710978 scopus 로고
    • Characteristics of a human cell line transformed by DNA from human adenovirus type 5
    • Graham FL, Smiley J, Russell WC, Nairn R, (1977) Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 36: 59-74.
    • (1977) J Gen Virol , vol.36 , pp. 59-74
    • Graham, F.L.1    Smiley, J.2    Russell, W.C.3    Nairn, R.4
  • 42
    • 0036618178 scopus 로고    scopus 로고
    • Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells
    • Shaw G, Morse S, Ararat M, Graham FL, (2002) Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J 16: 869-871.
    • (2002) FASEB J , vol.16 , pp. 869-871
    • Shaw, G.1    Morse, S.2    Ararat, M.3    Graham, F.L.4
  • 44
    • 0018121341 scopus 로고
    • Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones
    • Biedler JL, Roffler-Tarlov S, Schachner M, Freedman LS, (1978) Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res 38: 3751-3757.
    • (1978) Cancer Res , vol.38 , pp. 3751-3757
    • Biedler, J.L.1    Roffler-Tarlov, S.2    Schachner, M.3    Freedman, L.S.4
  • 46
    • 77955268518 scopus 로고    scopus 로고
    • The NSD3L histone methyltransferase regulates cell cycle and cell invasion in breast cancer cells
    • Zhou Z, Thomsen R, Kahns S, Nielsen AL, (2010) The NSD3L histone methyltransferase regulates cell cycle and cell invasion in breast cancer cells. Biochem Biophys Res Commun 398: 565-570.
    • (2010) Biochem Biophys Res Commun , vol.398 , pp. 565-570
    • Zhou, Z.1    Thomsen, R.2    Kahns, S.3    Nielsen, A.L.4
  • 47
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE, (2002) Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 30: 207-210.
    • (2002) Nucleic Acids Res , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 48
    • 33745612095 scopus 로고    scopus 로고
    • Pvclust: an R package for assessing the uncertainty in hierarchical clustering
    • Suzuki R, Shimodaira H, (2006) Pvclust: an R package for assessing the uncertainty in hierarchical clustering. Bioinformatics 22: 1540-1542.
    • (2006) Bioinformatics , vol.22 , pp. 1540-1542
    • Suzuki, R.1    Shimodaira, H.2
  • 49
    • 78149461229 scopus 로고    scopus 로고
    • Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue
    • Liu-Yesucevitz L, Bilgutay A, Zhang YJ, Vanderwyde T, Citro A, et al. (2010) Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue. PLoS One 5: e13250.
    • (2010) PLoS One , vol.5
    • Liu-Yesucevitz, L.1    Bilgutay, A.2    Zhang, Y.J.3    Vanderwyde, T.4    Citro, A.5
  • 50
    • 79952589652 scopus 로고    scopus 로고
    • TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1
    • McDonald KK, Aulas A, Destroismaisons L, Pickles S, Beleac E, et al. (2011) TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1. Hum Mol Genet 20: 1400-1410.
    • (2011) Hum Mol Genet , vol.20 , pp. 1400-1410
    • McDonald, K.K.1    Aulas, A.2    Destroismaisons, L.3    Pickles, S.4    Beleac, E.5
  • 51
    • 42649120983 scopus 로고    scopus 로고
    • TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
    • Kabashi E, Valdmanis PN, Dion P, Spiegelman D, McConkey BJ, et al. (2008) TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat Genet 40: 572-574.
    • (2008) Nat Genet , vol.40 , pp. 572-574
    • Kabashi, E.1    Valdmanis, P.N.2    Dion, P.3    Spiegelman, D.4    McConkey, B.J.5
  • 52
    • 84872746545 scopus 로고    scopus 로고
    • King's College London, The Institute of Psychiatry website
    • ALS online genetics database, King's College London, The Institute of Psychiatry website. Available: http://alsod.iop.kcl.ac.uk/Accessed 2012 Aug 31.
    • ALS online genetics database
  • 53
    • 0030935567 scopus 로고    scopus 로고
    • Cytochrome P-4502E1: its physiological and pathological role
    • Lieber CS, (1997) Cytochrome P-4502E1: its physiological and pathological role. Physiol Rev 77: 517-544.
    • (1997) Physiol Rev , vol.77 , pp. 517-544
    • Lieber, C.S.1
  • 54
    • 41349117373 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 in the substantia nigra: relevance for dopaminergic neurotransmission and free radical production
    • Shahabi HN, Andersson DR, Nissbrandt H, (2008) Cytochrome P450 2E1 in the substantia nigra: relevance for dopaminergic neurotransmission and free radical production. Synapse 62: 379-388.
    • (2008) Synapse , vol.62 , pp. 379-388
    • Shahabi, H.N.1    Andersson, D.R.2    Nissbrandt, H.3
  • 55
    • 67349285751 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 gene polymorphisms/haplotypes and Parkinson's disease in a Swedish population
    • Shahabi HN, Westberg L, Melke J, Hakansson A, Belin AC, et al. (2009) Cytochrome P450 2E1 gene polymorphisms/haplotypes and Parkinson's disease in a Swedish population. J Neural Transm 116: 567-573.
    • (2009) J Neural Transm , vol.116 , pp. 567-573
    • Shahabi, H.N.1    Westberg, L.2    Melke, J.3    Hakansson, A.4    Belin, A.C.5
  • 56
    • 0033588164 scopus 로고    scopus 로고
    • Kinetics of cytochrome P450 2E1-catalyzed oxidation of ethanol to acetic acid via acetaldehyde
    • Bell-Parikh LC, Guengerich FP, (1999) Kinetics of cytochrome P450 2E1-catalyzed oxidation of ethanol to acetic acid via acetaldehyde. J Biol Chem 274: 23833-23840.
    • (1999) J Biol Chem , vol.274 , pp. 23833-23840
    • Bell-Parikh, L.C.1    Guengerich, F.P.2
  • 58
    • 79951533960 scopus 로고    scopus 로고
    • Smoking and risk of amyotrophic lateral sclerosis: a pooled analysis of 5 prospective cohorts
    • Wang H, O'Reilly EJ, Weisskopf MG, Logroscino G, McCullough ML, et al. (2011) Smoking and risk of amyotrophic lateral sclerosis: a pooled analysis of 5 prospective cohorts. Arch Neurol 68: 207-213.
    • (2011) Arch Neurol , vol.68 , pp. 207-213
    • Wang, H.1    O'Reilly, E.J.2    Weisskopf, M.G.3    Logroscino, G.4    McCullough, M.L.5
  • 59


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