-
1
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen, D.R. et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62 (1993).
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
-
2
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
-
DeJesus-Hernandez, M. et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 72, 245-256 (2011).
-
(2011)
Neuron
, vol.72
, pp. 245-256
-
-
Dejesus-Hernandez, M.1
-
3
-
-
80054837386
-
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
-
Renton, A.E. et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 72, 257-268 (2011).
-
(2011)
Neuron
, vol.72
, pp. 257-268
-
-
Renton, A.E.1
-
4
-
-
79955913593
-
Phenotypic heterogeneity in a SOD1 G93D Italian ALS family: An example of human model to study a complex disease
-
Penco, S. et al. Phenotypic heterogeneity in a SOD1 G93D Italian ALS family: an example of human model to study a complex disease. J. Mol. Neurosci. 44, 25-30 (2011).
-
(2011)
J. Mol. Neurosci
, vol.44
, pp. 25-30
-
-
Penco, S.1
-
5
-
-
78650438932
-
Anticipation and phenotypic heterogeneity in Korean familial amyotrophic lateral sclerosis with superoxide dismutase 1 gene mutation
-
Kim, W. et al. Anticipation and phenotypic heterogeneity in Korean familial amyotrophic lateral sclerosis with superoxide dismutase 1 gene mutation. J. Clin. Neurol. 3, 38-44 (2007).
-
(2007)
J. Clin. Neurol
, vol.3
, pp. 38-44
-
-
Kim, W.1
-
6
-
-
34447306605
-
Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality
-
Fogh, I. et al. Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality. Neurogenetics 8, 235-236 (2007).
-
(2007)
Neurogenetics
, vol.8
, pp. 235-236
-
-
Fogh, I.1
-
7
-
-
34548740744
-
Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish
-
Lemmens, R. et al. Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish. Hum. Mol. Genet. 16, 2359-2365 (2007).
-
(2007)
Hum. Mol. Genet
, vol.16
, pp. 2359-2365
-
-
Lemmens, R.1
-
8
-
-
78149429744
-
Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy
-
Laird, A.S. et al. Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy. PLoS ONE 5, e13368 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Laird, A.S.1
-
9
-
-
15744397834
-
EphA4 is required for cell adhesion and rhombomere-boundary formation in the zebrafish
-
Cooke, J.E., Kemp, H.A. & Moens, C.B. EphA4 is required for cell adhesion and rhombomere-boundary formation in the zebrafish. Curr. Biol. 15, 536-542 (2005).
-
(2005)
Curr. Biol
, vol.15
, pp. 536-542
-
-
Cooke, J.E.1
Kemp, H.A.2
Moens, C.B.3
-
10
-
-
13344261393
-
Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain
-
Xu, Q., Alldus, G., Holder, N. & Wilkinson, D.G. Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain. Development 121, 4005-4016 (1995).
-
(1995)
Development
, vol.121
, pp. 4005-4016
-
-
Xu, Q.1
Alldus, G.2
Holder, N.3
Wilkinson, D.G.4
-
11
-
-
58149138860
-
Bidirectional modulation of synaptic functions by Eph/ephrin signaling
-
Klein, R. Bidirectional modulation of synaptic functions by Eph/ephrin signaling. Nat. Neurosci. 12, 15-20 (2009).
-
(2009)
Nat. Neurosci
, vol.12
, pp. 15-20
-
-
Klein, R.1
-
12
-
-
13144259630
-
EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract
-
Dottori, M. et al. EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract. Proc. Natl. Acad. Sci. USA 95, 13248-13253 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13248-13253
-
-
Dottori, M.1
-
13
-
-
0037459382
-
Role of EphA4 and EphrinB3 in local neuronal circuits that control walking
-
Kullander, K. et al. Role of EphA4 and EphrinB3 in local neuronal circuits that control walking. Science 299, 1889-1892 (2003).
-
(2003)
Science
, vol.299
, pp. 1889-1892
-
-
Kullander, K.1
-
14
-
-
57649178194
-
Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors
-
Noberini, R. et al. Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors. J. Biol. Chem. 283, 29461-29472 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 29461-29472
-
-
Noberini, R.1
-
15
-
-
8544237780
-
Axonal regeneration and lack of astrocytic gliosis in EphA4-deficient mice
-
Goldshmit, Y., Galea, M.P., Wise, G., Bartlett, P.F. & Turnley, A.M. Axonal regeneration and lack of astrocytic gliosis in EphA4-deficient mice. J. Neurosci. 24, 10064-10073 (2004).
-
(2004)
J. Neurosci
, vol.24
, pp. 10064-10073
-
-
Goldshmit, Y.1
Galea, M.P.2
Wise, G.3
Bartlett, P.F.4
Turnley, A.M.5
-
16
-
-
35949001327
-
Regeneration-enhancing effects of EphA4 blocking peptide following corticospinal tract injury in adult rat spinal cord
-
Fabes, J., Anderson, P., Brennan, C. & Bolsover, S. Regeneration-enhancing effects of EphA4 blocking peptide following corticospinal tract injury in adult rat spinal cord. Eur. J. Neurosci. 26, 2496-2505 (2007).
-
(2007)
Eur. J. Neurosci
, vol.26
, pp. 2496-2505
-
-
Fabes, J.1
Anderson, P.2
Brennan, C.3
Bolsover, S.4
-
17
-
-
80052774673
-
EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice
-
Goldshmit, Y. et al. EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice. PLoS ONE 6, e24636 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Goldshmit, Y.1
-
18
-
-
70349559398
-
Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport
-
Filosa, A. et al. Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport. Nat. Neurosci. 12, 1285-1292 (2009).
-
(2009)
Nat. Neurosci
, vol.12
, pp. 1285-1292
-
-
Filosa, A.1
-
19
-
-
0026597010
-
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
-
Rothstein, J.D., Martin, L.J. & Kuncl, R.W. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N. Engl. J. Med. 326, 1464-1468 (1992).
-
(1992)
N. Engl. J. Med
, vol.326
, pp. 1464-1468
-
-
Rothstein, J.D.1
Martin, L.J.2
Kuncl, R.W.3
-
20
-
-
0029030610
-
Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
-
Rothstein, J.D., Van Kammen, M., Levey, A.I., Martin, L.J. & Kuncl, R.W. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann. Neurol. 38, 73-84 (1995).
-
(1995)
Ann. Neurol
, vol.38
, pp. 73-84
-
-
Rothstein, J.D.1
Van Kammen, M.2
Levey, A.I.3
Martin, L.J.4
Kuncl, R.W.5
-
21
-
-
19944428649
-
β-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
-
Rothstein, J.D. et al. β-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression. Nature 433, 73-77 (2005).
-
(2005)
Nature
, vol.433
, pp. 73-77
-
-
Rothstein, J.D.1
-
22
-
-
0027414379
-
Matching between motoneurone and muscle unit properties in rat medial gastrocnemius
-
Bakels, R. & Kernell, D. Matching between motoneurone and muscle unit properties in rat medial gastrocnemius. J. Physiol. (Lond.) 463, 307-324 (1993).
-
(1993)
J. Physiol. (Lond.)
, vol.463
, pp. 307-324
-
-
Bakels, R.1
Kernell, D.2
-
23
-
-
0027535315
-
Physiological properties of motoneurons innervating different muscle unit types in rat gastrocnemius
-
Gardiner, P.F. Physiological properties of motoneurons innervating different muscle unit types in rat gastrocnemius. J. Neurophysiol. 69, 1160-1170 (1993).
-
(1993)
J. Neurophysiol
, vol.69
, pp. 1160-1170
-
-
Gardiner, P.F.1
-
24
-
-
0034175513
-
Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases
-
Frey, D. et al. Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases. J. Neurosci. 20, 2534-2542 (2000).
-
(2000)
J. Neurosci
, vol.20
, pp. 2534-2542
-
-
Frey, D.1
-
25
-
-
33344462702
-
Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF
-
Pun, S., Santos, A.F., Saxena, S., Xu, L. & Caroni, P. Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF. Nat. Neurosci. 9, 408-419 (2006).
-
(2006)
Nat. Neurosci
, vol.9
, pp. 408-419
-
-
Pun, S.1
Santos, A.F.2
Saxena, S.3
Xu, L.4
Caroni, P.5
-
26
-
-
35148814074
-
Transcriptional profiling of Alzheimer blood mononuclear cells by microarray
-
Maes, O.C. et al. Transcriptional profiling of Alzheimer blood mononuclear cells by microarray. Neurobiol. Aging 28, 1795-1809 (2007).
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 1795-1809
-
-
Maes, O.C.1
-
27
-
-
23344448837
-
Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease
-
Borovecki, F. et al. Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease. Proc. Natl. Acad. Sci. USA 102, 11023-11028 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 11023-11028
-
-
Borovecki, F.1
-
28
-
-
1842839794
-
Lymphocytes as a neural probe: Potential for studying psychiatric disorders. Prog. Neuropsychopharmacol
-
Gladkevich, A., Kauffman, H.F. & Korf, J. Lymphocytes as a neural probe: potential for studying psychiatric disorders. Prog. Neuropsychopharmacol. Biol. Psychiatry 28, 559-576 (2004).
-
(2004)
Biol. Psychiatry
, vol.28
, pp. 559-576
-
-
Gladkevich, A.1
Kauffman, H.F.2
Korf, J.3
-
29
-
-
27344436234
-
Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia
-
Glatt, S.J. et al. Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia. Proc. Natl. Acad. Sci. USA 102, 15533-15538 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 15533-15538
-
-
Glatt, S.J.1
-
30
-
-
48749114218
-
Fibroblast and lymphoblast gene expression profiles in schizophrenia: Are non-neural cells informative?
-
Matigian, N.A. et al. Fibroblast and lymphoblast gene expression profiles in schizophrenia: are non-neural cells informative? PLoS ONE 3, e2412 (2008).
-
(2008)
PLoS ONE
, vol.3
-
-
Matigian, N.A.1
-
31
-
-
12944277034
-
Assessing the validity of blood-based gene expression profiles for the classification of schizophrenia and bipolar disorder: A preliminary report
-
Tsuang, M.T. et al. Assessing the validity of blood-based gene expression profiles for the classification of schizophrenia and bipolar disorder: a preliminary report. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 133B, 1-5 (2005).
-
(2005)
Am. J. Med. Genet. B. Neuropsychiatr. Genet
, vol.133 B
, pp. 1-5
-
-
Tsuang, M.T.1
-
32
-
-
84857487802
-
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression
-
Fu, J. et al. Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet. 8, e1002431 (2012).
-
(2012)
PLoS Genet
, vol.8
-
-
Fu, J.1
-
33
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
Sreedharan, J. et al. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science 319, 1668-1672 (2008).
-
(2008)
Science
, vol.319
, pp. 1668-1672
-
-
Sreedharan, J.1
-
34
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann, M. et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314, 130-133 (2006).
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
-
35
-
-
41949119043
-
TDP-43 A315T mutation in familial motor neuron disease
-
Gitcho, M.A. et al. TDP-43 A315T mutation in familial motor neuron disease. Ann. Neurol. 63, 535-538 (2008).
-
(2008)
Ann. Neurol
, vol.63
, pp. 535-538
-
-
Gitcho, M.A.1
-
36
-
-
0042887389
-
Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding
-
McWhorter, M.L., Monani, U.R., Burghes, A.H. & Beattie, C.E. Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding. J. Cell Biol. 162, 919-931 (2003).
-
(2003)
J. Cell Biol
, vol.162
, pp. 919-931
-
-
McWhorter, M.L.1
Monani, U.R.2
Burghes, A.H.3
Beattie, C.E.4
-
37
-
-
16644382257
-
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
-
Storkebaum, E. et al. Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS. Nat. Neurosci. 8, 85-92 (2005).
-
(2005)
Nat. Neurosci
, vol.8
, pp. 85-92
-
-
Storkebaum, E.1
-
38
-
-
0026465350
-
Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons
-
Cashman, N.R. et al. Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons. Dev. Dyn. 194, 209-221 (1992).
-
(1992)
Dev. Dyn
, vol.194
, pp. 209-221
-
-
Cashman, N.R.1
|