-
1
-
-
34249949338
-
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
-
Amador-Ortiz C., Lin W. L., Ahmed Z., Personett D., Davies P., Duara R., Graff-Radford N. R., Hutton M. L., and, Dickson D. W., (2007) TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann. Neurol. 61, 435-445.
-
(2007)
Ann. Neurol.
, vol.61
, pp. 435-445
-
-
Amador-Ortiz, C.1
Lin, W.L.2
Ahmed, Z.3
Personett, D.4
Davies, P.5
Duara, R.6
Graff-Radford, N.R.7
Hutton, M.L.8
Dickson, D.W.9
-
2
-
-
33846794896
-
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
-
Amaravadi R. K., Yu D., Lum J. J., Bui T., Christophorou M. A., Evan G. I., Thomas-Tikhonenko A., and, Thompson C. B., (2007) Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J. Clin. Invest. 117, 326-336.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 326-336
-
-
Amaravadi, R.K.1
Yu, D.2
Lum, J.J.3
Bui, T.4
Christophorou, M.A.5
Evan, G.I.6
Thomas-Tikhonenko, A.7
Thompson, C.B.8
-
3
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Arai T., Hasegawa M., Akiyama H., et al. (2006) TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem. Biophys. Res. Commun. 351, 602-611.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
-
4
-
-
21344463770
-
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation
-
Babu J. R., Geetha T., and, Wooten M. W., (2005) Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation. J. Neurochem. 94, 192-203.
-
(2005)
J. Neurochem.
, vol.94
, pp. 192-203
-
-
Babu, J.R.1
Geetha, T.2
Wooten, M.W.3
-
5
-
-
77952766891
-
Autophagy: Assays and artifacts
-
Barth S., Glick D., and, Macleod K. F., (2010) Autophagy: assays and artifacts. J. Pathol. 221, 117-124.
-
(2010)
J. Pathol.
, vol.221
, pp. 117-124
-
-
Barth, S.1
Glick, D.2
MacLeod, K.F.3
-
6
-
-
77955897545
-
Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations
-
Baumer D., Hilton D., Paine S. M., Turner M. R., Lowe J., Talbot K., and, Ansorge O., (2010) Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations. Neurology 75, 611-618.
-
(2010)
Neurology
, vol.75
, pp. 611-618
-
-
Baumer, D.1
Hilton, D.2
Paine, S.M.3
Turner, M.R.4
Lowe, J.5
Talbot, K.6
Ansorge, O.7
-
7
-
-
38449102667
-
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease
-
Buratti E., and, Baralle F. E., (2008) Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease. Front Biosci. 13, 867-878.
-
(2008)
Front Biosci.
, vol.13
, pp. 867-878
-
-
Buratti, E.1
Baralle, F.E.2
-
8
-
-
27844514227
-
TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: An important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing
-
Buratti E., Brindisi A., Giombi M., Tisminetzky S., Ayala Y. M., and, Baralle F. E., (2005) TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing. J. Biol. Chem. 280, 37572-37584.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37572-37584
-
-
Buratti, E.1
Brindisi, A.2
Giombi, M.3
Tisminetzky, S.4
Ayala, Y.M.5
Baralle, F.E.6
-
9
-
-
79954427132
-
New neuropathological findings in Unverricht-Lundborg disease: Neuronal intranuclear and cytoplasmic inclusions
-
in press.
-
Cohen N. R., Hammans S. R., Macpherson J., and, Nicoll J. A., (2010) New neuropathological findings in Unverricht-Lundborg disease: neuronal intranuclear and cytoplasmic inclusions. Acta Neuropathol. in press.
-
(2010)
Acta Neuropathol.
-
-
Cohen, N.R.1
Hammans, S.R.2
MacPherson, J.3
Nicoll, J.A.4
-
10
-
-
77952932485
-
FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis
-
Deng H. X., Zhai H., Bigio E. H., et al. (2010) FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis. Ann. Neurol. 67, 739-748.
-
(2010)
Ann. Neurol.
, vol.67
, pp. 739-748
-
-
Deng, H.X.1
Zhai, H.2
Bigio, E.H.3
-
11
-
-
67650432367
-
Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin
-
Dormann D., Capell A., Carlson A. M., et al. (2009) Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin. J. Neurochem. 110, 1082-1094.
-
(2009)
J. Neurochem.
, vol.110
, pp. 1082-1094
-
-
Dormann, D.1
Capell, A.2
Carlson, A.M.3
-
12
-
-
14844342815
-
The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins
-
Dosztanyi Z., Csizmok V., Tompa P., and, Simon I., (2005) The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins. J. Mol. Biol. 347, 827-839.
-
(2005)
J. Mol. Biol.
, vol.347
, pp. 827-839
-
-
Dosztanyi, Z.1
Csizmok, V.2
Tompa, P.3
Simon, I.4
-
13
-
-
35948983328
-
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
-
Filimonenko M., Stuffers S., Raiborg C., Yamamoto A., Malerod L., Fisher E. M., Isaacs A., Brech A., Stenmark H., and, Simonsen A., (2007) Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J. Cell Biol. 179, 485-500.
-
(2007)
J. Cell Biol.
, vol.179
, pp. 485-500
-
-
Filimonenko, M.1
Stuffers, S.2
Raiborg, C.3
Yamamoto, A.4
Malerod, L.5
Fisher, E.M.6
Isaacs, A.7
Brech, A.8
Stenmark, H.9
Simonsen, A.10
-
14
-
-
47949108734
-
TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration
-
Foulds P., McAuley E., Gibbons L., Davidson Y., Pickering-Brown S. M., Neary D., Snowden J. S., Allsop D., and, Mann D. M., (2008) TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration. Acta Neuropathol. 116, 141-146.
-
(2008)
Acta Neuropathol.
, vol.116
, pp. 141-146
-
-
Foulds, P.1
McAuley, E.2
Gibbons, L.3
Davidson, Y.4
Pickering-Brown, S.M.5
Neary, D.6
Snowden, J.S.7
Allsop, D.8
Mann, D.M.9
-
15
-
-
78650707221
-
Numerous FUS-positive inclusions in an elderly woman with motor neuron disease
-
[Epub ahead of print].
-
Fujita Y., Fujita S., Takatama M., Ikeda M., and, Okamoto K., (2010) Numerous FUS-positive inclusions in an elderly woman with motor neuron disease. Neuropathology [Epub ahead of print].
-
(2010)
Neuropathology
-
-
Fujita, Y.1
Fujita, S.2
Takatama, M.3
Ikeda, M.4
Okamoto, K.5
-
16
-
-
70350131893
-
Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism
-
Gal J., Strom A. L., Kwinter D. M., Kilty R., Zhang J., Shi P., Fu W., Wooten M. W., and, Zhu H., (2009) Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism. J. Neurochem. 111, 1062-1073.
-
(2009)
J. Neurochem.
, vol.111
, pp. 1062-1073
-
-
Gal, J.1
Strom, A.L.2
Kwinter, D.M.3
Kilty, R.4
Zhang, J.5
Shi, P.6
Fu, W.7
Wooten, M.W.8
Zhu, H.9
-
17
-
-
77956106755
-
Autophagy, a guardian against neurodegeneration
-
Garcia-Arencibia M., Hochfeld W. E., Toh P. P., and, Rubinsztein D. C., (2010) Autophagy, a guardian against neurodegeneration. Semin. Cell Dev. Biol. 21, 691-698.
-
(2010)
Semin. Cell Dev. Biol.
, vol.21
, pp. 691-698
-
-
Garcia-Arencibia, M.1
Hochfeld, W.E.2
Toh, P.P.3
Rubinsztein, D.C.4
-
18
-
-
51049118332
-
The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: Beyond the usual suspects' review series
-
Geng J., and, Klionsky D. J., (2008) The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series. EMBO Rep. 9, 859-864.
-
(2008)
EMBO Rep.
, vol.9
, pp. 859-864
-
-
Geng, J.1
Klionsky, D.J.2
-
19
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T., Nakamura K., Matsui M., et al. (2006) Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441, 885-889.
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
-
20
-
-
47949086625
-
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Hasegawa M., Arai T., Nonaka T., et al. (2008) Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Ann. Neurol. 64, 60-70.
-
(2008)
Ann. Neurol.
, vol.64
, pp. 60-70
-
-
Hasegawa, M.1
Arai, T.2
Nonaka, T.3
-
21
-
-
36348972414
-
Concurrence of TDP-43, tau and alpha-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies
-
Higashi S., Iseki E., Yamamoto R., et al. (2007) Concurrence of TDP-43, tau and alpha-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies. Brain Res. 1184, 284-294.
-
(2007)
Brain Res.
, vol.1184
, pp. 284-294
-
-
Higashi, S.1
Iseki, E.2
Yamamoto, R.3
-
22
-
-
67649797399
-
Expression of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 proteinopathies
-
Igaz L. M., Kwong L. K., Chen-Plotkin A., Winton M. J., Unger T. L., Xu Y., Neumann M., Trojanowski J. Q., and, Lee V. M., (2009) Expression of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 proteinopathies. J. Biol. Chem. 284, 8516-8524.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 8516-8524
-
-
Igaz, L.M.1
Kwong, L.K.2
Chen-Plotkin, A.3
Winton, M.J.4
Unger, T.L.5
Xu, Y.6
Neumann, M.7
Trojanowski, J.Q.8
Lee, V.M.9
-
23
-
-
48749088629
-
Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS
-
Inukai Y., Nonaka T., Arai T., et al. (2008) Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS. FEBS Lett. 582, 2899-2904.
-
(2008)
FEBS Lett.
, vol.582
, pp. 2899-2904
-
-
Inukai, Y.1
Nonaka, T.2
Arai, T.3
-
24
-
-
40449127705
-
Neuropathological aspects of Alzheimer disease, Parkinson disease and frontotemporal dementia
-
Jellinger K. A., (2008) Neuropathological aspects of Alzheimer disease, Parkinson disease and frontotemporal dementia. Neurodegener. Dis. 5, 118-121.
-
(2008)
Neurodegener. Dis.
, vol.5
, pp. 118-121
-
-
Jellinger, K.A.1
-
25
-
-
74049124412
-
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
-
Ju J. S., Fuentealba R. A., Miller S. E., Jackson E., Piwnica-Worms D., Baloh R. H., and, Weihl C. C., (2009) Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease. J. Cell Biol. 187, 875-888.
-
(2009)
J. Cell Biol.
, vol.187
, pp. 875-888
-
-
Ju, J.S.1
Fuentealba, R.A.2
Miller, S.E.3
Jackson, E.4
Piwnica-Worms, D.5
Baloh, R.H.6
Weihl, C.C.7
-
26
-
-
42649120983
-
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
-
Kabashi E., Valdmanis P. N., Dion P., et al. (2008) TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat. Genet. 40, 572-574.
-
(2008)
Nat. Genet.
, vol.40
, pp. 572-574
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
-
27
-
-
68149159190
-
Phosphorylation-dependent TDP-43 antibody detects intraneuronal dot-like structures showing morphological characters of granulovacuolar degeneration
-
Kadokura A., Yamazaki T., Kakuda S., Makioka K., Lemere C. A., Fujita Y., Takatama M., and, Okamoto K., (2009) Phosphorylation-dependent TDP-43 antibody detects intraneuronal dot-like structures showing morphological characters of granulovacuolar degeneration. Neurosci. Lett. 463, 87-92.
-
(2009)
Neurosci. Lett.
, vol.463
, pp. 87-92
-
-
Kadokura, A.1
Yamazaki, T.2
Kakuda, S.3
Makioka, K.4
Lemere, C.A.5
Fujita, Y.6
Takatama, M.7
Okamoto, K.8
-
28
-
-
63349083295
-
Identification of casein kinase-1 phosphorylation sites on TDP-43
-
Kametani F., Nonaka T., Suzuki T., Arai T., Dohmae N., Akiyama H., and, Hasegawa M., (2009) Identification of casein kinase-1 phosphorylation sites on TDP-43. Biochem. Biophys. Res. Commun. 382, 405-409.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.382
, pp. 405-409
-
-
Kametani, F.1
Nonaka, T.2
Suzuki, T.3
Arai, T.4
Dohmae, N.5
Akiyama, H.6
Hasegawa, M.7
-
29
-
-
77958604956
-
ALS-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to coregulate HDAC6 mRNA
-
Kim S. H., Shanware N., Bowler M. J., and, Tibbetts R. S., (2010) ALS-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to coregulate HDAC6 mRNA. J. Biol. Chem. 285, 34097-34105.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34097-34105
-
-
Kim, S.H.1
Shanware, N.2
Bowler, M.J.3
Tibbetts, R.S.4
-
30
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
Kwiatkowski T. J., Jr, Bosco D. A., Leclerc A. L., et al. (2009) Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 323, 1205-1208.
-
(2009)
Science
, vol.323
, pp. 1205-1208
-
-
Kwiatkowski, Jr.T.J.1
Bosco, D.A.2
Leclerc, A.L.3
-
31
-
-
77955784599
-
ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS
-
Ling S. C., Albuquerque C. P., Han J. S., Lagier-Tourenne C., Tokunaga S., Zhou H., and, Cleveland D. W., (2010) ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS. Proc. Natl Acad. Sci. USA 107, 13318-13323.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 13318-13323
-
-
Ling, S.C.1
Albuquerque, C.P.2
Han, J.S.3
Lagier-Tourenne, C.4
Tokunaga, S.5
Zhou, H.6
Cleveland, D.W.7
-
32
-
-
34547733547
-
Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases
-
Nakashima-Yasuda H., Uryu K., Robinson J., et al. (2007) Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases. Acta Neuropathol. 114, 221-229.
-
(2007)
Acta Neuropathol.
, vol.114
, pp. 221-229
-
-
Nakashima-Yasuda, H.1
Uryu, K.2
Robinson, J.3
-
33
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M., Sampathu D. M., Kwong L. K., et al. (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314, 130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
-
34
-
-
59249085091
-
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies
-
Neumann M., Kwong L. K., Lee E. B., et al. (2009) Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathol. 117, 137-149.
-
(2009)
Acta Neuropathol.
, vol.117
, pp. 137-149
-
-
Neumann, M.1
Kwong, L.K.2
Lee, E.B.3
-
35
-
-
67650113333
-
Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43
-
Nonaka T., Kametani F., Arai T., Akiyama H., and, Hasegawa M., (2009) Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43. Hum. Mol. Genet. 18, 3353-3364.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 3353-3364
-
-
Nonaka, T.1
Kametani, F.2
Arai, T.3
Akiyama, H.4
Hasegawa, M.5
-
36
-
-
34548259958
-
P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
Pankiv S., Clausen T. H., Lamark T., Brech A., Bruun J. A., Outzen H., Overvatn A., Bjorkoy G., and, Johansen T., (2007) p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J. Biol. Chem. 282, 24131-24145.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.A.5
Outzen, H.6
Overvatn, A.7
Bjorkoy, G.8
Johansen, T.9
-
37
-
-
3142514201
-
Protein aggregation and neurodegenerative disease
-
Ross C. A., and, Poirier M. A., (2004) Protein aggregation and neurodegenerative disease. Nat. Med. 10 (Suppl.), S10-S17.
-
(2004)
Nat. Med.
, vol.10
, Issue.SUPPL.
-
-
Ross, C.A.1
Poirier, M.A.2
-
38
-
-
52949094629
-
Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis
-
Rutherford N. J., Zhang Y. J., Baker M., et al. (2008) Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis. PLoS Genet. 4, e1000193.
-
(2008)
PLoS Genet.
, vol.4
-
-
Rutherford, N.J.1
Zhang, Y.J.2
Baker, M.3
-
39
-
-
58149398638
-
Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of huntington disease
-
Schwab C., Arai T., Hasegawa M., Yu S., and, McGeer P. L., (2008) Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of huntington disease. J. Neuropathol. Exp. Neurol. 67, 1159-1165.
-
(2008)
J. Neuropathol. Exp. Neurol.
, vol.67
, pp. 1159-1165
-
-
Schwab, C.1
Arai, T.2
Hasegawa, M.3
Yu, S.4
McGeer, P.L.5
-
40
-
-
4444220680
-
Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation
-
Seibenhener M. L., Babu J. R., Geetha T., Wong H. C., Krishna N. R., and, Wooten M. W., (2004) Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. Mol. Cell. Biol. 24, 8055-8068.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8055-8068
-
-
Seibenhener, M.L.1
Babu, J.R.2
Geetha, T.3
Wong, H.C.4
Krishna, N.R.5
Wooten, M.W.6
-
41
-
-
33846240526
-
Sequestosome 1/p62 - More than just a scaffold
-
Seibenhener M. L., Geetha T., and, Wooten M. W., (2007) Sequestosome 1/p62-more than just a scaffold. FEBS Lett. 581, 175-179.
-
(2007)
FEBS Lett.
, vol.581
, pp. 175-179
-
-
Seibenhener, M.L.1
Geetha, T.2
Wooten, M.W.3
-
42
-
-
77958022745
-
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
-
Shan X., Chiang P. M., Price D. L., and, Wong P. C., (2010) Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proc. Natl Acad. Sci. USA 107, 16325-16330.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 16325-16330
-
-
Shan, X.1
Chiang, P.M.2
Price, D.L.3
Wong, P.C.4
-
43
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
Sreedharan J., Blair I. P., Tripathi V. B., et al. (2008) TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science 319, 1668-1672.
-
(2008)
Science
, vol.319
, pp. 1668-1672
-
-
Sreedharan, J.1
Blair, I.P.2
Tripathi, V.B.3
-
44
-
-
68949221689
-
Ubiquitin-like and ubiquitin-associated domain proteins: Significance in proteasomal degradation
-
Su V., and, Lau A. F., (2009) Ubiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradation. Cell. Mol. Life Sci. 66, 2819-2833.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 2819-2833
-
-
Su, V.1
Lau, A.F.2
-
45
-
-
44649137415
-
Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies
-
Uryu K., Nakashima-Yasuda H., Forman M. S., et al. (2008) Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies. J. Neuropathol. Exp. Neurol. 67, 555-564.
-
(2008)
J. Neuropathol. Exp. Neurol.
, vol.67
, pp. 555-564
-
-
Uryu, K.1
Nakashima-Yasuda, H.2
Forman, M.S.3
-
46
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
Vance C., Rogelj B., Hortobagyi T., et al. (2009) Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science 323, 1208-1211.
-
(2009)
Science
, vol.323
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobagyi, T.3
-
47
-
-
13244291416
-
Use of polyethyleneimine polymer in cell culture as attachment factor and lipofection enhancer
-
Vancha A. R., Govindaraju S., Parsa K. V., Jasti M., Gonzalez-Garcia M., and, Ballestero R. P., (2004) Use of polyethyleneimine polymer in cell culture as attachment factor and lipofection enhancer. BMC Biotechnol. 4, 23.
-
(2004)
BMC Biotechnol.
, vol.4
, pp. 23
-
-
Vancha, A.R.1
Govindaraju, S.2
Parsa, K.V.3
Jasti, M.4
Gonzalez-Garcia, M.5
Ballestero, R.P.6
-
48
-
-
54249100481
-
TDP-43: An emerging new player in neurodegenerative diseases
-
Wang I. F., Wu L. S., and, Shen C. K., (2008) TDP-43: an emerging new player in neurodegenerative diseases. Trends Mol. Med. 14, 479-485.
-
(2008)
Trends Mol. Med.
, vol.14
, pp. 479-485
-
-
Wang, I.F.1
Wu, L.S.2
Shen, C.K.3
-
49
-
-
73249152831
-
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
-
Wegorzewska I., Bell S., Cairns N. J., Miller T. M., and, Baloh R. H., (2009) TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Proc. Natl Acad. Sci. USA 106, 18809-18814.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 18809-18814
-
-
Wegorzewska, I.1
Bell, S.2
Cairns, N.J.3
Miller, T.M.4
Baloh, R.H.5
-
50
-
-
77649269011
-
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
-
Wils H., Kleinberger G., Janssens J., Pereson S., Joris G., Cuijt I., Smits V., Ceuterick-de Groote C., Van Broeckhoven C., and, Kumar-Singh S., (2010) TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration. Proc. Natl Acad. Sci. USA 107, 3858-3863.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 3858-3863
-
-
Wils, H.1
Kleinberger, G.2
Janssens, J.3
Pereson, S.4
Joris, G.5
Cuijt, I.6
Smits, V.7
Ceuterick-De Groote, C.8
Van Broeckhoven, C.9
Kumar-Singh, S.10
-
51
-
-
44749091997
-
Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
-
Winton M. J., Igaz L. M., Wong M. M., Kwong L. K., Trojanowski J. Q., and, Lee V. M., (2008) Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J. Biol. Chem. 283, 13302-13309.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13302-13309
-
-
Winton, M.J.1
Igaz, L.M.2
Wong, M.M.3
Kwong, L.K.4
Trojanowski, J.Q.5
Lee, V.M.6
-
52
-
-
77951214016
-
Mammalian autophagy: Core molecular machinery and signaling regulation
-
Yang Z., and, Klionsky D. J., (2009) Mammalian autophagy: core molecular machinery and signaling regulation. Curr. Opin. Cell Biol. 22, 124-131.
-
(2009)
Curr. Opin. Cell Biol.
, vol.22
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
53
-
-
55849133733
-
Identification of SCF ubiquitin ligase substrates by global protein stability profiling
-
Yen H. C., and, Elledge S. J., (2008) Identification of SCF ubiquitin ligase substrates by global protein stability profiling. Science 322, 923-929.
-
(2008)
Science
, vol.322
, pp. 923-929
-
-
Yen, H.C.1
Elledge, S.J.2
-
54
-
-
42949094584
-
TDP-43 mutation in familial amyotrophic lateral sclerosis
-
Yokoseki A., Shiga A., Tan C. F., et al. (2008) TDP-43 mutation in familial amyotrophic lateral sclerosis. Ann. Neurol. 63, 538-542.
-
(2008)
Ann. Neurol.
, vol.63
, pp. 538-542
-
-
Yokoseki, A.1
Shiga, A.2
Tan, C.F.3
-
55
-
-
34848921202
-
Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43
-
Zhang Y. J., Xu Y. F., Dickey C. A., Buratti E., Baralle F., Bailey R., Pickering-Brown S., Dickson D., and, Petrucelli L., (2007) Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. J. Neurosci. 27, 10530-10534.
-
(2007)
J. Neurosci.
, vol.27
, pp. 10530-10534
-
-
Zhang, Y.J.1
Xu, Y.F.2
Dickey, C.A.3
Buratti, E.4
Baralle, F.5
Bailey, R.6
Pickering-Brown, S.7
Dickson, D.8
Petrucelli, L.9
-
56
-
-
66149114101
-
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
-
Zhang Y. J., Xu Y. F., Cook C., et al. (2009) Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc. Natl Acad. Sci. USA 106, 7607-7612.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 7607-7612
-
-
Zhang, Y.J.1
Xu, Y.F.2
Cook, C.3
-
57
-
-
85040709233
-
Phosphorylation regulates proteasomal-mediated degradation and solubility of TAR DNA binding protein-43 C-terminal fragments
-
Zhang Y. J., Gendron T. F., Xu Y. F., Ko L. W., Yen S. H., and, Petrucelli L., (2010) Phosphorylation regulates proteasomal-mediated degradation and solubility of TAR DNA binding protein-43 C-terminal fragments. Mol. Neurodegener. 5, 33.
-
(2010)
Mol. Neurodegener.
, vol.5
, pp. 33
-
-
Zhang, Y.J.1
Gendron, T.F.2
Xu, Y.F.3
Ko, L.W.4
Yen, S.H.5
Petrucelli, L.6
|