TDP-43 and FUS RNA-binding proteins bind distinct sets of cytoplasmic messenger RNAs and differently regulate their post-transcriptional fate in motoneuron-like cells

Journal of Biological Chemistry

Volumn 287, Issue 19, 2012, Pages 15635-15647

  Colombrita, Claudia ^a   Onesto, Elisa ^a   Megiorni, Francesca ^b   Pizzuti, Antonio ^b   Baralle, Francisco E ^c   Buratti, Emanuele ^c   Silani, Vincenzo ^a,d   Ratti, Antonia ^a,d  

^a ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; BINDING AFFINITIES; BINDING MOTIF; BIOINFORMATICS ANALYSIS; CELLULAR PATHWAY; CONSENSUS MOTIF; IMMUNOPRECIPITATIONS; IN-VITRO ASSAYS; MESSENGER RNA; NEURODEGENERATION; POINT MUTATIONS; POST-TRANSCRIPTIONAL; PRE-MRNA; PROTEIN CONTENTS; PROTEIN LEVEL; RIBONUCLEOPROTEIN COMPLEX; RNA METABOLISMS; RNA-BINDING PROTEIN;

BINDING ENERGY; BIOINFORMATICS; CYTOLOGY; NEURODEGENERATIVE DISEASES; NEURONS; PROTEINS; TISSUE;

RNA;

FUS RNA BINDING PROTEIN; MESSENGER RNA; PROGRANULIN; PROTEIN GRN; PROTEIN NVL; PROTEIN TAF15; PROTEIN VEGFA; PROTEIN VPS54; RIBONUCLEOPROTEIN; RNA BINDING PROTEIN; TDP 43 RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOINFORMATICS; CELL COMPARTMENTALIZATION; CELL FATE; CELL FUNCTION; CONTROLLED STUDY; CYTOPLASM; IMMUNOPRECIPITATION; IN VITRO STUDY; MOTONEURON; MOUSE; NERVE DEGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MICROARRAY; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN TARGETING; RNA METABOLISM; RNA STABILITY; RNA TRANSLATION; RNA TRANSPORT;

3' UNTRANSLATED REGIONS; ANIMALS; BLOTTING, WESTERN; CELL LINE; CYTOPLASM; DNA-BINDING PROTEINS; HUMANS; IMMUNOPRECIPITATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MOTOR NEURONS; MUTATION; NUCLEOTIDE MOTIFS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEIN FUS; TATA-BINDING PROTEIN ASSOCIATED FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VESICULAR TRANSPORT PROTEINS;

EID: 84860863883     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.333450     Document Type: Article

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