Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms

Biochemistry

Volumn 50, Issue 44, 2011, Pages 9446-9456

  Combs, Benjamin ^a   Voss, Kellen ^a   Gamblin, T Chris ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATION PROPERTY; ALZHEIMERS DISEASE; CONFORMATIONAL EFFECT; DIFFERENTIAL EFFECT; HYPERPHOSPHORYLATED; HYPERPHOSPHORYLATION; IN-VITRO; ISOFORMS; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULES; N-TERMINALS; TAUOPATHIES;

ELECTROPHORETIC MOBILITY; PHOSPHORYLATION;

NEURODEGENERATIVE DISEASES;

ISOPROTEIN; MICROTUBULE PROTEIN; MUTANT PROTEIN; TAU PROTEIN; THIOFLAVINE; TUBULIN;

AMINO TERMINAL SEQUENCE; ARTICLE; ELECTROPHORESIS; IN VITRO STUDY; LIGHT SCATTERING; MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PSEUDOHYPERPHOSPHORYLATION; TAUOPATHY; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID SUBSTITUTION; ARACHIDONIC ACID; ASPARTIC ACID; BIOPOLYMERS; GLUTAMIC ACID; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN ISOFORMS; SERINE; TAU PROTEINS; TAUOPATHIES; THREONINE;

PHOS;

EID: 80155166000     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2010569     Document Type: Article

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